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Malignant Mesothelioma
| Malignant Mesothelioma |
| Autore | L. Pouliquen Daniel |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (328 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
well-differentiated papillary mesothelioma
WDPM malignant mesothelioma DNA sequencing mutation mesothelioma tumor suppressor targeted therapy immunotherapy biomarkers proteomics macrophage-capping protein fatty acid-binding protein laminin subunit beta-2 selenium-binding protein 1 carcinogenesis malignant pleural mesothelioma asbestos exposure DNA methylation lymphocyte-to-monocyte ratio epigenome-wide analysis survival analysis metabolomics radiotherapy cancers inflammation infiltrating immune cells prognostic biomarker predictive biomarker immune therapy VATS extrapleural pneumonectomy pleurectomy decortication therapy response survival FDG PET-CT mesothelium oxidative stress redox-sensitive factors asbestos carbon nanotubes protein-protein interactions systems biology network analysis drug repurposing pleural mesothelioma gene expression immunogenicity sarcomatoid epithelioid first line meta-analysis systematic review MPM lurbinectedin DNA damage response histotype Hippo pathway NF2 BAP1 CDKN2A PTCH1 SETD2 MTAP liquid biopsies circulating tumor DNA plasma cancer-specific mutations genomics cancer biomarkers tumor microenvironment tumor-associated macrophages dendritic cells immunohistochemistry interaction analysis pleural effusion |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557359303321 |
L. Pouliquen Daniel
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Metastatic Progression and Tumour Heterogeneity
| Metastatic Progression and Tumour Heterogeneity |
| Autore | Hollande Fred |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (312 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
clear cell renal cell carcinoma
tumor evolution tumor ecology intratumor heterogeneity multisite tumor sampling targeted therapy uterine carcinosarcoma endometrial carcinoma metaplastic carcinoma epithelial-to-mesenchymal transition clonality mutation TP53 PI3K/AKT pathway gene expression miRNA expression tumor microenvironment interstitial pH acidosis tumor heterogeneity magnetic resonance imaging hyperpolarized 13C MRI carbonic anhydrase lactic acid positron emission tomography esophageal squamous cell carcinoma precision medicine natural killer cells tumor mutation burden immunotherapy PET heterogeneity radiomics radiopharmaceuticals SUV nuclear medicine colon cancer Wnt signaling phenotypic plasticity EMT hybrid E/M collective and single-cell migration beta-catenin paradox breast cancer immune microenvironment DCIS ADH mammary gland cell fate 3D cultures organoids signaling single-cell RNAseq tumor endothelial cell metastasis angiocrine factor microsatellite instability colorectal cancer immune checkpoints deficient mismatch repair plasticity biomechanics circulating tumor cells (CTCs) extracellular vesicles metastatic niche epigenetics CTC-clusters single-cell analysis cellular heterogeneity circulating tumor cells pancreatic cancer epithelial mesenchymal plasticity target discovery review genomics intra-tumour heterogeneity subclonal diversity treatment resistance |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557105803321 |
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Hollande Fred
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Methods in Computational Biology
| Methods in Computational Biology |
| Autore | Carlson Ross |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (214 p.) |
| Soggetto non controllato |
inosine
immune checkpoint inhibitor geometric singular perturbation theory simulation BioModels Database ADAR calcium current bifurcation analysis bacterial biofilms nonlinear dynamics explanatory model turning point bifurcation oscillator workflow bioreactor integrated modeling modeling methods elementary flux modes visualization multiscale systems biology evolutionary algorithm metabolic model differential evolution reduced-order model computational model gut microbiota dysbiosis canard-induced EADs computational biology metabolic modelling methods SREBP-2 mechanistic model systems modeling biological networks macromolecular composition provenance flux balance analysis immunotherapy compartmental modeling immuno-oncology metabolic network visualization mechanism bistable switch Clostridium difficile infection bioreactor operation optimization microRNA targeting CFD simulation biomass reaction RNA editing ordinary differential equation metabolic modeling mass-action networks hybrid model multiple time scales quantitative systems pharmacology (QSP) mathematical modeling microRNA cancer parameter optimization Hopf bifurcation breast |
| ISBN | 3-03921-164-1 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910346689103321 |
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Carlson Ross
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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MicroRNA and Cancer
| MicroRNA and Cancer |
| Autore | Tucci Paola |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (298 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
Breast cancer
Hypoxia inducible factor 1-alpha (HIF-1α) MicroRNA (miRNA) miR526b miR655 Oxidative stress Migration Cyclooxygenase-2 (COX-2) Prostaglandin E2 receptor 4 (EP4) PI3K/Akt adipokines endometrial cancer estrogens hyperinsulinemia insulin insulin resistance insulin signaling insulin-like growth factors microRNA miRNA ovarian cancer survival prognostic factor serum LDH blood biomarker circulating microRNA plasma immunotherapy immune checkpoint inhibitors metastatic melanoma hepatocellular carcinoma metastasis exosome bioinformatics analysis renal cancer RCC ccRCC meta-analysis miRNAs normal B-cell development B-CLL miRNA-transcription factor network regulation biomarker therapy prognosis diagnosis progression prediction smoking non-small cell lung cancer methylation miR-584-5p YKT6 snoRNA 2'-O-methylation pseudouridylation malignant melanoma cancer stem cell stemness head and neck squamous cell carcinoma colon cancer cancer stem cells microRNAs deformability PARP replication stress targeted therapy breast cancer circulating biomarkers medulloblastoma brain tumour subgroups stem cells |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910580213503321 |
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Tucci Paola
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Molecular Pathways in Cancers
| Molecular Pathways in Cancers |
| Autore | Cristóbal Ion |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (284 p.) |
| Soggetto topico |
Medicine
Oncology |
| Soggetto non controllato |
actin cytoskeletal reorganization
breast cancer CD99 agonist EGFR dimerization endocytosis FAK dephosphorylation PTPN12 Rac1 RhoA tripeptide OMD PRELP tumor suppression gene bladder cancer initiation tight junction partial EMT tousled-like kinase (TLK) NIMA-related kinase 1 (NEK1) yes-associated protein 1 (YAP1) thioridazine (THD) MS-determined phosphopeptides human immunodeficiency virus type 1 epithelial cells carcinogenicity oxidative stress reactive oxygen species gp120 Tat Nef matrix protein p17 reverse transcriptase mitochondria metastasis OXPHOS cancer Warburg effect cancer therapeutics myeloproliferative neoplasms signaling pathways JAK2 CALR MPL TPOR DUSP1 MAPK Snail prostate cancer migration and invasion patient survival biomarkers pBRD4 SET PP2A prognosis triple negative breast cancer resistance anti-receptor therapy trastuzumab PI3K mTOR TAK-228 epigenetic methylation acetylation non-coding RNA small-cell lung cancer triple-negative breast cancer pancreatic ductal adenocarcinoma glioblastoma metastatic melanoma advanced ovarian cancer hepatocellular carcinoma immune evasion immunotherapy immune checkpoint inhibitors oncogenic signaling pathway molecular targeted agents genome epigenome tumor immune microenvironment ovarian cancer adaptive immunity innate immunity complement system cancer immunology tumor microenvironment splicing pathway luminal breast cancer BET inhibitors |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910566473703321 |
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Cristóbal Ion
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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mTOR in Human Diseases
| mTOR in Human Diseases |
| Autore | Dormond Olivier |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (480 p.) |
| Soggetto non controllato |
primary cilia
neurodegeneration nutrient sensor PI3K transcriptomics phosphorylation metabolic reprogramming autophagy Alzheimer's disease rapalogs liver angiogenesis mTOR complex MBSCs advanced biliary tract cancers Medulloblastoma epithelial to mesenchymal transition AMPK p70S6K lipid metabolism thyroid cancer sodium iodide symporter (NIS)/SLC5A5 male fertility anesthesia illumina mTOR inhibitor miRNA Hutchinson-Gilford progeria syndrome (HGPS) eIFs Emery-Dreifuss muscular dystrophy (EDMD) glucose AKT oral cavity squamous cell carcinoma (OSCC) glucose and lipid metabolism cellular signaling aging tumor microenvironment rapamycin leukemia chloral hydrate rapalogues schizophrenia T-cell acute lymphoblastic leukemia senescence lamin A/C neurotoxicity neurodevelopment inhibitor methamphetamine pulmonary fibrosis mTOR mTOR inhibitors combination therapy proteolysis fluid shear stress tumour cachexia biomarkers synapse gluconeogenesis mTOR signal pathway Sertoli cells immunosenescence miRNome protein aggregation senolytics metabolism NGS mTORC2 mTORC1 metabolic diseases IonTorrent apoptosis dopamine receptor nocodazole microenvironment everolimus acute myeloid leukemia immunotherapy spermatogenesis bone remodeling signalling targeted therapy ageing therapy NVP-BEZ235 fructose physical activity laminopathies MC3T3-E1 cells cell signaling microRNA cancer lipolysis melatonin Parkinson's disease |
| ISBN | 3-03921-061-0 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910346684303321 |
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Dormond Olivier
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Multimodal Therapy of Upper Gastrointestinal Malignancies
| Multimodal Therapy of Upper Gastrointestinal Malignancies |
| Autore | Ronellenfitsch Ulrich |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (272 p.) |
| Soggetto topico | Public health & preventive medicine |
| Soggetto non controllato |
gastric cancer
gastrectomy complications outcome survival lymph node ratio neoadjuvant chemotherapy conversion surgery cancer dormancy nuclear receptor NR2F1 clinical pathways gastric surgery oncological gastrectomy quality of care outcomes standardization adjuvant therapy gastrointestinal tract genetic diagnosis radiosensitivity mortality failure to rescue immunotherapy genetics esophageal cancer multidisciplinary gastric/gastroesophageal cancer perioperative chemotherapy overall survival relapse-free survival skeletal muscle index esophagectomy nutritional status sarcopenia esophageal anastomosis minimally invasive surgery induction chemotherapy chemo-radiotherapy neoadjuvant treatment esophageal squamous cell carcinoma multimodal treatment neoadjuvant chemoradiotherapy definitive chemoradiotherapy Lauren histotype gastrointestinal stromal tumor neuroendocrine tumor MALT lymphoma mucosal resection submucosal dissection GIST stomach neoadjuvant therapy imatinib organ preservation squamous cell esophageal cancer gastro-esophageal reflux disease Barrett's esophagus early adenocarcinoma of esophagus endoscopic submucosal dissection endoscopic mucosal resection |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557781603321 |
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Ronellenfitsch Ulrich
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Multimodality Treatments in Metastatic Gastric Cancer
| Multimodality Treatments in Metastatic Gastric Cancer |
| Autore | Petrillo Angelica |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (162 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
advanced gastric cancer
precision medicine new drug development gastro-oesophageal cancer mutational concordance exome sequencing formalin fixed paraffin embedded biomarkers gastric cancer metastatic body composition sarcopenia visceral fat area subcutaneous fat area outcome toxicity liver metastasis conversion surgery hepatectomy stage iv gastric cancer immune checkpoint inhibitors Epstein Barr Virus tumor mutational burden microsatellite instability predictive biomarkers CAR T cell therapy vaccines nutritional status metastatic gastric cancer target therapy bone flare stage IV treatment RANK-L liquid biopsy circulating tumor cell cfDNA ctDNA epithelial-mesenchymal transition resistance to treatment HER2-inhibition VEGFR-inhibition immunotherapy response monitoring |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557390503321 |
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Petrillo Angelica
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Nanoprobes for Tumor Theranostics
| Nanoprobes for Tumor Theranostics |
| Autore | Shen Zheyu |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (208 p.) |
| Soggetto topico |
Technology: general issues
Chemical engineering |
| Soggetto non controllato |
aptamers
nanomaterials cancer treatment targeting NIR-II fluorescent probes activatable strategy NIR-II fluorescence imaging biomarker biosensing ferritin drug delivery thermally induced drug loading computational analysis iron oxide nanoparticles magnetotheranostics aggregation-induced emission NIR-II emission phototheranostics cancer treatment dendrimers gold nanoparticles CpG-ODN immunotherapy T cells ion interference therapy ions inorganic nanoparticles SERS Raman microbeads multiplex immunoassays circulating tumor cells ovarian cancer folic acid fluorescent-magnetic nanoparticles isolation identification living sample viability measurement atomic force microscopy AFM oscillating sensor method nanomotion |
| ISBN | 3-0365-6160-9 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910639993403321 |
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Shen Zheyu
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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New Therapies of Liver Diseases
| New Therapies of Liver Diseases |
| Autore | Toniutto Pierluigi |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (236 p.) |
| Soggetto topico | Public health & preventive medicine |
| Soggetto non controllato |
tolvaptan
cirrhotic ascites survival rate furosemide primary biliary cholangitis autoantibodies ursodeoxycholic acid treatment response second line therapy primary biliary cholangitis (PBC) primary sclerosing cholangitis (PSC) clinical trials ursodeoxycholic acid (UDCA) Farnesoid X Receptor (FXR) agonist Pan-Peroxisome Proliferator-Activated Receptor (PPAR) agonists liver cancer systemic treatment immunotherapy real-world unresectable hepatocellular carcinoma cirrhosis decompensation bleeding varices survival infection alcoholic hepatitis acute-on-chronic liver failure cholangiocarcinoma colorectal cancer metastases hepatocellular carcinoma liver transplantation Milan criteria alpha-fetoprotein solid organ transplantation liver injury immunosuppressant SARS-CoV-2 humoral response vaccination portal-systemic shunt ammonia vigilance HBV HDV antivirals functional cure pharmacology acute-on-chronic liver failure (ACLF) liver transplantation (LT) decompensated cirrhosis portal hypertension ascites non-selective beta-blockers TIPS rifaximin human albumin statins targeted therapy effective hypovolemia anti-mineralocorticoids loop diuretics vaptans |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910566457403321 |
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Toniutto Pierluigi
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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