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Brain-Targeted Drug Delivery
| Brain-Targeted Drug Delivery |
| Autore | Sousa Flávia |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (260 p.) |
| Soggetto topico | Technology: general issues |
| Soggetto non controllato |
drug delivery into the brain
transendothelium based on receptor-mediated transcytosis immunotherapy Alzheimer's disease anti-tau and anti-receptor bispecific monoclonal antibodies Alzheimer's disease-relevant tau species temporal-spatial pathological Aβ and tau distribution interactions between Aβ and tau tau clearance in microglia tau clearance in neurons liposome nanoparticle seizure laser ultrasound naringenin nanostructured lipid carrier intranasal delivery central composite rotatable design depression pomegranate seed oil nasal delivery system memory impairment movement impairment delivery to brain improved memory phospholipid oily gel high-grade glioma diffuse midline glioma glioblastoma IL-13Rα2 IL-13 immunotoxin targeted therapy GB-13 IL13.E13K-PE4E receptor expression acetaminophen blood-brain barrier claudin-5 CNS drug delivery opioids tight junction microdialysis cerebral open flow microperfusion electrochemical biosensors macromolecules tolcapone microparticles nanoparticles PLGA Parkinson's disease nose to brain delivery gene therapy polyplexes hyaluronidase glycol chitosan brain cancer chemoattractant CXCL CXCR glioblastoma multiforme 3D cell culture systems non-human primate convection-enhanced delivery neurosurgery optogenetics brain targeted therapy drug delivery cerebrospinal fluid microcirculation brain biodistribution |
| ISBN | 3-0365-5281-2 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910619467203321 |
Sousa Flávia
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| MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Cancer Biomarkers and Targets in Digestive Organs
| Cancer Biomarkers and Targets in Digestive Organs |
| Autore | Lee Nikki |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (146 p.) |
| Soggetto non controllato |
liver graft injury
HFE neurokinin chemotherapy intestinal tumors therapeutic targets biliary tract carcinoma hepatocellular carcinoma clinical trial cell adhesion molecules colorectal cancer biomarkers phenotypic mosaics gastrointestinal oncology Asian Cancer Research Group (ACRG) biomarker psychosocial support precision therapy pancreatic carcinoma precision medicine Liver transplantation predictive biomarkers CD274 cholecystokinin The Cancer Genome Atlas (TCGA) gastrin pembrolizumab immunotherapy gastrin-releasing peptide stereotactic body radiation therapy immunohistochemistry gastric carcinoma liver transplant CAM invasion assay intragraft gene expression profiles molecular profiling targeted therapy neurotensin intestinal disorder ramucirumab next-generation sequencing colorectal carcinoma tumor progenitor circulating tumor cells gastrointestinal malignancies bombesin trastuzumab somatostatin zebrafish G protein-coupled receptors |
| ISBN | 3-03921-464-0 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910367564003321 |
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Lee Nikki
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Cancer Immunology
| Cancer Immunology |
| Autore | Subramanian Subree |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (316 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
NKG2D
CAR T IL-7 prostate cancer cell therapy CD19-CAR-T B cell aplasia KIR PD-1 inhibitory CAR tumor-infiltrating lymphocytes tumor microenvironment immunotherapy NK cells cancer stem cells (CSCs) antibody-dependent cellular cytotoxicity (ADCC) differentiation cytotoxicity IFN-γ osteoclasts MICA/B mAb DNA methylation RNA methylation S-adenosylmethionine (SAM) cancer innate immunity adaptive immunity T cells m6A PD-L1 resistance immune checkpoints cancer vaccine combination immunotherapy TCR diversity organ transplantation carcinoma epidemiologic studies immunosuppression CTLA-4 Treg cells immune checkpoint inhibitors CD28 antigen-presenting cells IL15 colon cancer melanoma uveal BAP1 anti-PD-1 anti-CTLA-4 TIL classical and endemic Kaposi Sarcoma systemic treatment multi-state modelling treatment free interval chemotherapy interferon triple negative breast cancer immunomodulation bispecific antibody sortase A chemo-enzymatic approach anti-CD20 antibody Fab BiFab colorectal cancer dendritic cells Atypical Chemokine Receptor 4 (ACKR4) T-cell priming immune checkpoint blockade primary liver cancer kynurenine pathway immune evasion indoleamine 2,3 dioxygenase 1 tryptophan 2,3 dioxygenase 2 IDO inhibitor antigen presenting cells |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557349203321 |
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Subramanian Subree
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Cancer Metabolism: Molecular Targeting and Implications for Therapy
| Cancer Metabolism: Molecular Targeting and Implications for Therapy |
| Autore | Shanmugasundaram Ganapathy-Kanniappan |
| Pubbl/distr/stampa | Frontiers Media SA, 2017 |
| Descrizione fisica | 1 electronic resource (114 p.) |
| Collana | Frontiers Research Topics |
| Soggetto non controllato |
Tumor microenvironment
metastasis Cancer Metabolism glycolysis immunotherapy epigenetic regulation metabolic reprogramming Warburg effect |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Cancer Metabolism |
| Record Nr. | UNINA-9910688412403321 |
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Shanmugasundaram Ganapathy-Kanniappan
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| Frontiers Media SA, 2017 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Cancer Nanomedicine
| Cancer Nanomedicine |
| Autore | Hoskins Clare |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (510 p.) |
| Soggetto topico | Technology: general issues |
| Soggetto non controllato |
antibody drug conjugate (ADC)
PD-L1 tumor spheroid disruption immune modulation doxorubicin graphene oxide adsorption cathepsin D cathepsin L anti-metastatic enzyme cancer therapy nanoparticles targeted delivery system siRNA osteopontin mammary carcinoma mesenchymal stem cells (MSCs) TAT peptide PLGA paclitaxel nano-engineered MSCs orthotopic lung tumor model intracranial glioma immunotherapy CPMV viral nanoparticles in situ vaccine albumin nanoparticles microbubble ultrasound theranostics hepatocellular carcinoma VX2 tumor intra-arterial chemotherapy lung cancer nanomedicine clinical status cancer therapy breast cancer cell signaling active targeting passive targeting EPR effect oncogenes nanoparticle drug delivery ligand tumor targeting biodistribution Mesoporous silica nanoparticle drug delivery system target treatment lanthanide metal hyaluronic acid hyaluronidase drug combination everolimus dual-targeting magnetic nanoparticles monoclonal antibodies nanostructured lipid carrier platelet membrane biomimicry plasmonic photothermal therapy gold nanorods surgery bleeding dogs cats stimuli-responsive DOX SN38 CSCs single-walled carbon nanotubes chirality separation NASH drug-gene delivery near IR hyperspectral imaging plasmonics copper VEGF glioblastoma differentiated neuroblastoma peptidomimetics real-time quantitative polymerase chain reaction (qPCR) actin combinatorial therapy anticancer and antibacterial activity temoporfin drug-in-cyclodextrin-in-liposome hybrid nanoparticles multicellular tumor spheroids cyclodextrins photodynamic therapy article yet reasonably common within the subject discipline antitumor strategy biomimetic core–shell nanoparticles NK cell-derived exosomes folate receptor albumin nanoparticle microfluidic cabazitaxel polydopamine nanoparticles size cytotoxicity iron affinity FA-DABA-SMA self-assembly oncogenic proteins intracellular disruption folic receptor alpha pancreatic cancer parvifloron D albumin erlotinib photodynamic therapy lipid nanoparticles tumor vectorization verteporfin ovarian carcinomatosis spheroids integrin RGD peptide cancer diagnosis radiotherapy hyperthermia therapy biomimetic nanocarrier membrane-wrapped cancer targeted delivery photothermal therapy imaging cancer nanomedicine tumor microenvironment nano–bio interactions clinical translation magnetic nanowires magnetic hyperthermia magnetic actuation magnetic drug targeting titanate nanotubes gold nanoparticles vectorization colloidal stability docetaxel prostate cancer mangiferin anti-topoisomerase activity extracellular vesicles exosomes chemico-physical functionalization loading translational medicine nanotechnology: bioengineering anacardic acid mitoxantrone targeted drug delivery liposomes melanoma apoptosis ascorbic acid angiogenesis epithelial-to-mesenchymal transition hypoxia immunosuppression metabolism nanotherapeutics tumour microenvironment DNA origami liposome remote loading acute toxicity organoids magnetic silica-coated iron oxide nanochains photothermal treatment hyperthermia collagen cellular microenvironment lymphadenectomy magnetometer sentinel lymph node dissection SPION superparamagnetic iron oxide nanoparticles Vδ2 T cells zoledronic acid polymeric nanoconstruct anti-tumor immunity colorectal carcinoma β-cyclodextrin nanosponges BALB-neuT mice brain tumours glioma blood brain barrier polymeric nanoparticles PEGylation dioleoylphosphatidylethanolamine poly(hydroxyethyl acrylate-co-allyl methyl sulfide) copolymer folate oxidation-sensitive release cellular interaction in vitro anti-cancer activity triple negative breast cancer organotin mesoporous silica nanoparticles MDA-MB-231 theranostic nanomaterials nanobiotechnology molecular imaging nanosystems nanomicelles ovarian cancer tumour targeting chemotherapeutics riboflavin vitamin B2 nanomedicines secondary structure mixed micelle pH responsive targeted therapy anti-cancer shear stress flow in vitro therapeutics diagnostics Immunotherapy |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557114703321 |
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Hoskins Clare
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Critical Issues in Head and Neck Oncology : Key Concepts from the Seventh THNO Meeting / / edited by Jan B. Vermorken, Volker Budach, C. René Leemans, Jean-Pascal Machiels, Piero Nicolai, Brian O’Sullivan
| Critical Issues in Head and Neck Oncology : Key Concepts from the Seventh THNO Meeting / / edited by Jan B. Vermorken, Volker Budach, C. René Leemans, Jean-Pascal Machiels, Piero Nicolai, Brian O’Sullivan |
| Autore | Vermorken Jan B |
| Edizione | [1st ed. 2021.] |
| Pubbl/distr/stampa | Springer Nature, 2021 |
| Descrizione fisica | 1 online resource (IX, 373 p. 39 illus., 33 illus. in color.) |
| Disciplina | 616.994 |
| Soggetto topico |
Oncology
Radiotherapy Surgical oncology Oncology Surgical Oncology Càncer de coll Càncer de cap Cirurgia oncològica |
| Soggetto genere / forma | Llibres electrònics |
| Soggetto non controllato |
Oncology
Radiotherapy Surgical Oncology Internal Medicine Radiology Surgery Nasopharynx cancer Head and Neck Squamous Cell Cancer non-oropharyngeal head and neck cancer predictive biomarkers liquid biopsies induction chemotherapy immunotherapy precision medicine HNSCC Open Access |
| ISBN | 3-030-63234-2 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Biomarkers in Head and Neck Squamous Cell Cancer (HNSCC) -- Promising biomarkers for early diagnosis and prognosis prediction in HNS -- Biomarkers to predict radiotherapy toxicity -- Biomarkers for hypoxia, HPVness and proliferation from imaging perspective -- Mechanism of cetuximab resistance and how to overcome it -- The role of liquid biopsy for monitoring disease evolution -- NK cells in immunotherapy: how important are they? -- Biomarkers for immune modulatory treatment in HNSCC -- Primary disease (1) -- Novel approaches in surgical management of HNSCC -- The surgical approach to elderly patients with HNSCC -- The nonsurgical approach to locoregionally advanced HNSCC -- High-dose three-weekly or low-dose weekly cisplatin during radiation, what to prefer? -- Primary disease (2) -- Where and when to use induction chemotherapy? -- Prognostic role of p16/HPV in non-oropharyngeal head and neck cancer -- Is there a role for neoadjuvant targeted and immunotherapies? -- Is there a role for adjuvant targeted and immunotherapies? -- Optimal supportive measures during primary treatment -- Precision Medicine in head and neck cancer: myth or reality -- Recurrent and / or metastatic disease -- Salvage surgery: candidates, safe reconstruction, and results? -- Re-irradiation for local relapses or second primaries: when and how? -- New promising targeted agents in first and second-line settings -- Update of immune therapies in recurrent/metastatic HNSCC -- Special Issue -- Patients with rare head neck cancers: do they need a different approach? .-Nasopharynx cancer -- New epidemiological aspects -- New developments in the management of nasopharyngeal carcinoma -- New drugs for recurrent/metastatic nasopharynx cancer. |
| Record Nr. | UNINA-9910484360603321 |
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Vermorken Jan B
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| Springer Nature, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Current Perspectives, Challenges and Advances in Cell Based Therapies
| Current Perspectives, Challenges and Advances in Cell Based Therapies |
| Autore | Trikha Prashant |
| Pubbl/distr/stampa | Frontiers Media SA, 2020 |
| Descrizione fisica | 1 electronic resource (192 p.) |
| Soggetto topico |
Medicine
Oncology |
| Soggetto non controllato |
immunotherapy
NK cell tumor micoenvironment CAR (chimeric antigen receptor) T cells cell based therapy |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557622203321 |
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Trikha Prashant
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| Frontiers Media SA, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Delivery of Molecules Using Nanoscale Systems for Cancer Treatment and/or Diagnosis
| Delivery of Molecules Using Nanoscale Systems for Cancer Treatment and/or Diagnosis |
| Autore | Franco Marina Santiago |
| Pubbl/distr/stampa | Basel, : MDPI Books, 2022 |
| Descrizione fisica | 1 electronic resource (302 p.) |
| Soggetto topico |
Medicine
Pharmacology |
| Soggetto non controllato |
nanostructured lipid carriers
doxorubicin mucositis cell internalization albumin BSA CPP gold nanorods gold nanoprisms arginine-rich peptide glutathione nanoparticles oxidative stress breast cancer gastric cancer nanoparticle fucoidan d-alpha-tocopherylpoly (ethylene glycol) succinate combination chemotherapy G-quadruplex nucleolin DNA nanocages intracellular localization cancer targeting molecular dynamics simulations mesoporous silica nanoparticles radiotherapy immunotherapy tumor microenvironment abscopal effect magnetofection in vivo magnetic nanoparticles iron oxide gene delivery gene vectors codelivery nanocarriers photodynamic therapy anticancer therapies combination therapy phthalocyanine uterine cervical neoplasms photochemotherapy in vitro in vivo nanocarrier polyplexes siRNA delivery glioblastoma therapy amphiphilic poly(α)glutamate P-selectin prodrug drug delivery targeted therapy chemotherapy prostate cancer prostate-specific membrane antigen targeted delivery encapsulation cabazitaxel nanocarriers nanosystems radiosensitizer hypoxia synergism cancer photothermal therapy combined antitumor effect oxygenation hydrogel hypoxic tumor |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910595074103321 |
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Franco Marina Santiago
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| Basel, : MDPI Books, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Diabetology: Feature Papers 2021
| Diabetology: Feature Papers 2021 |
| Autore | Clifton Peter |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (158 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
carpal tunnel syndrome
ultrasound power doppler signal diabetes FINDRISC prediabetes metabolic syndrome young-adults N-acetyl-β-d-glucosaminidase (NAG) diabetic nephropathy chronic kidney disease (CKD) meta-analysis systematic review focus groups self-management of type 2 diabetes patients' experiences healthcare professionals middle-aged population type 1 diabetes autoimmune diseases pancreatic β-cells tolerance regulatory T cells immunotherapy insulin banting best MacLeod collip limited-resource countries (LRC) insulin pumps blood glucose monitoring continuous blood glucose sensors COVID-19 SARS-CoV-2 ACE2 TMPRSS2 mucormycosis COVID-associated mucormycosis (CAM) mucins Diabetic Keto Acidosis (DKA) Metabolic-Stress-Associated Interactome (MSAI) olfactory neurovascular niche serine proteases ferroptosis redox-iron stress |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Diabetology |
| Record Nr. | UNINA-9910576881103321 |
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Clifton Peter
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Diagnostic, Prognostic and Predictive Biological Markers in Bladder Cancer - Illumination of a Vision 2.0
| Diagnostic, Prognostic and Predictive Biological Markers in Bladder Cancer - Illumination of a Vision 2.0 |
| Autore | Ecke Thorsten |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (240 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
Metallothionein
urothelium urothelial cancer cadmium exposure zinc transporter bladder TAGLN F-actin PTEN p53 tumorigenesis proliferation invasion TERT promoter mutations FGFR3 non muscle invasive bladder cancer BCG therapy bladder cancer JAK-STAT pathway combination therapy oncolytic adenovirus virotherapy STAT3/5 inhibitor JAK inhibitor XVir-N-31 bladder cancer detection urinary biomarkers DNA methylation ECRG4 ITIH5 biomarker cancer grade metabolomics MS NMR biomarkers tumor markers prognosis heparanase syndecan-1 heparan sulfate proteoglycans (HSPGs) urothelial carcinoma miRNA quantitative PCR tumor marker voided urine cytology KDM7A histone demethylase TC-E 5002 androgen receptor drug resistance non-invasive detection telomerase somatic mutations TERT promoter region muscle-invasive bladder cancer chemotherapy immunotherapy personalized medicine predictive biomarker survivin BIRC5 macrophage KRT20 ERBB2 MIBC prediction RT-qPCR adjuvant chemotherapy survival |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557142003321 |
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Ecke Thorsten
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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