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Mechanisms and Novel Therapeutic Approaches for Gynecologic Cancer
| Mechanisms and Novel Therapeutic Approaches for Gynecologic Cancer |
| Autore | Nakayama Naomi |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (258 p.) |
| Soggetto topico | Public health & preventive medicine |
| Soggetto non controllato |
nucleus accumbens-associated protein 1 (NAC1)
BEN (BANP, E5R and NAC1) domain sequence-specific DNA-binding protein solution NMR structure isothermal titration calorimetry (ITC) human cytomegalovirus ovarian cancer cancer progression inflammation immunosuppression endometrial carcinoma immune micro-environment immune checkpoints inhibitors microsatellite instability mismatch repair deficiency platelet-activating factor acetylhydrolase (PAF-AH PLA2G7) BRCA1 mutant ovarian cancer Wnt signaling pGSK3β β-catenin prognosis vulvar melanoma vaginal melanoma targeted therapy gynecological cancer melanoma treatment gene ontology epithelial ovarian cancers borderline ovarian tumors differentially expressed genes aryl hydrocarbon receptor epithelial-mesenchymal transition integrative analysis testin p16 protein cervical cancer cervical neoplasia immunohistochemistry chimeric antigen receptor CD44 adoptive immunotherapy NK cells epithelial ovarian cancer DNA damage response somatic mutation clear cell carcinoma endometrioid endometrial cancer DNA mismatch repair (MMR) MMR deficient (dMMR) long-term survival exosome miRNA biomarkers liquid biopsy interventional radiotherapy vaginal-cuff brachytherapy HDR brachytherapy in vivo dosimetry endometrial cancer biological planning drug repurposing non-coding RNAs nanocarriers anti-angiogenic therapy |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910580209103321 |
Nakayama Naomi
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Molecular Basis of Inherited Diseases in Companion Animals
| Molecular Basis of Inherited Diseases in Companion Animals |
| Autore | Bannasch Danika |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (232 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
Canis familiaris
dermatology immunology animal model skin TLR7 toll-like receptor syndecan binding protein syntenin-1 systemic lupus erythematosus SLE CLE whole-genome sequencing craniomandibular osteopathy calvarial hyperostotic syndrome Caffey disease infantile cortical hyperostosis rare disease SLC37A2 COL1A1 SLC35D1 Canis lupus familiaris whole-genome sequence genodermatosis keratinocyte SAM syndrome precision medicine dog desmosome acantholysis calcium veterinary medicine feline Felis catus brain malformation BMP12 neurodevelopment genetics genomics mendelian traits genome-wide association study whole genome sequencing mitochondrion phosphoenolpyruvate-carboxykinase inborn error of metabolism encephalopathy SSADHD ALDH5A1 GABA 4-hydroxybutyric acid succinic semialdehyde GWAS inherited whole genome sequence wgs laminin Bardet-Biedl syndrome (BBS) primary cilia ciliopathy BBS8 progressive retinal atrophy (PRA) retinitis pigmentosa canine dystrophinopathy Duchenne immunohistochemistry neurometabolic disorder CHILD syndrome ILVEN epidermal nevus diabetes mellitus Burmese cats susceptibility single-nucleotide polymorphism genetic markers LIPH obesity companion animals metabolic disease comparative genomics dogs cats horses contactin neurological disorder Leonberger Saint Bernard Labrador retriever |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557141403321 |
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Bannasch Danika
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Molecular Psychiatry
| Molecular Psychiatry |
| Autore | Rein Theo |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (288 p.) |
| Soggetto topico |
Medicine
Mental health services |
| Soggetto non controllato |
cardiovascular disease
cell adhesion molecules immunology inflammation nervous system schizophrenia bipolar disorder major depressive disorder DNA methylation response variability antipsychotics drug design multi-target drugs polypharmacology multi-task learning machine learning biomarker discovery psychiatry serotonin 5-HT 4 receptor 5-HT4R depression mood disorder expression Alzheimer's disease cognition Parkinson's disease forced swimming Roman rat lines stress hippocampus BDNF trkB PSA-NCAM western blot immunohistochemistry general cognitive function intelligence GWAS genetic correlation childhood-onset schizophrenia (COS) induced pluripotent stem cell (iPSC) copy number variation (CNV) early neurodevelopment neuronal differentiation synapse dendritic arborization miRNAs stress physiology cytoskeleton actin dynamics DRR1 TU3A FAM107A acid sphingomyelinase alcohol dependence liver enzymes sphingolipid metabolism withdrawal Hsp90 GR stress response steroid hormones molecular chaperones psychiatric disease circadian rhythms FKBP51 FKBP52 CyP40 PP5 DISC1 neurodevelopment CRMP-2 proteomics antidepressant treatment HPA axis gene expression FKBP5 sleep sleep EEG biomarkers antidepressants cordance gender sex difference antidepressant rapid-acting Ketamine endocrinology (2R,6R)-Hydroxynorketamine electroconvulsive therapy basic-helix-loop-helix brain coactivator glucocorticoids mineralocorticoid receptor knockout transcription biology dopaminergic gene polymorphisms affective temperament obesity alpha-synuclein SNCA major depression Hamilton Scale of Depression chemokines neuroinflammation social defeat Immune response T cells susceptibility resilience Treg cells Th17 cells behavior PPARγ |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557793503321 |
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Rein Theo
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Molecular Research of Endometrial Pathophysiology
| Molecular Research of Endometrial Pathophysiology |
| Autore | Viganò Paola |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (378 p.) |
| Soggetto non controllato |
endometrial stromal cells
endometrial cell uterine cancer regeneration stem cell markers RANK chronic endometritis small RNA sequencing HOXA10 Vitamin D PPP2R1A molecular marker translational research angiogenesis endometriosis oestradiol mtDNA mutations antioxidant response protein phosphatase SMAP circulating tumour cells (CTCs) circulating tumour DNA (ctDNA) estrogen dependent endometrial regeneration mesenchymal stem cells endometrial cancer niche gene expression phosphoinositide 3-kinase lncRNAs mitochondrial biogenesis inflammation preclinical studies miRNA orthoxenograft tight junction proliferation aromatase testosterone CRISPR/Cas9 endometrium developmental pathway PP2A avatar infertility prognosis gene editing kinase inhibitor implantation haploinsufficiency contrast-enhanced CT scan pathway dehydroepiandrosterone (DHEA) CTCF PIK3CB zinc finger ectopic stroma liquid biopsy type II endometrial carcinoma eutopic and ectopic endometrium preclinical models EDN1 uterine aspirate cell contacts tumour suppressor gene pathogenomics mitochondrial dynamics adult stem cells PIK3CA murine models menstrual cycle immunomodulation decidualisation breakdown bioluminescence imaging protein kinase macrophages adherens junction exosomes immunohistochemistry orthotopic xenograft model decidualization p110? deficit of complex I targeted therapy mesenchymal stem cell sulfatase TRP channels personalized medicine mitophagy miR-375 migration microRNA gap junction cancer LGR5 miR-139-5p |
| ISBN | 3-03921-496-9 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910367752903321 |
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Viganò Paola
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Monitoring of Honey Bee Colony Losses
| Monitoring of Honey Bee Colony Losses |
| Autore | Gregorc Aleš |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (190 p.) |
| Soggetto topico |
Technology: general issues
Biotechnology |
| Soggetto non controllato |
Apis mellifera
honey bee colony losses biotic factors abiotic factors varroa mite detection diagnosis infestation mortality control organic treatment Apis cerana agriculture forests home garden neonicotinoid Tetragonula laeviceps Vespa velutina alien driver honey bee damage pollinator populations under study biological effects stress experimental methods techniques honey bees Varroa destructor experimental apiaries varroacidal efficacy VMP honeybee mortality incidents pesticide survey LC-MS/MS GC-MS/MS hydroxymethylfurfural cell death immunohistochemistry Nosema ceranae corn honeybee colony monitoring hive neonicotinoids oilseed rape sunflower varroa control colony losses forage beekeeping citizen science overwintering monitoring honey bee diseases stressors pathology honey bee mortalities colonies management BPMN hives monitoring IoT modeling & simulation interoperability sensors honeybee behavior Industry 4.0 workflow |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910566468503321 |
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Gregorc Aleš
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Neural Microelectrodes: Design and Applications
| Neural Microelectrodes: Design and Applications |
| Autore | Pancrazio Joseph |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (378 p.) |
| Soggetto non controllato |
closed-loop
in vivo imaging education thermoresistance neural probe electroless plating neural stimulation and recording peripheral nerve stimulation shape-memory-polymer artifact sensor interface magnetic coupling neuroprosthetics intracortical implant µECoG neural interfaces implantable electrochemistry shape memory polymer neuroscience micromachine microelectromechanical systems stiffness Parylene C intracranial electrodes chronic implantation neural interfacing microelectrodes multiplexing microstimulators freely-behaving windowed integration sampling system-on-chip brain-machine interfaces insertion force microelectrode array vagus nerve diversity micro-electromechanical systems (MEMS) technologies mixed-signal feedback temperature monitoring foreign body reaction peripheral nerves brain-computer interface multi-disciplinary neurotechnology photolithography micro-electrocorticography robust microelectrode conscious recording electrode array dopamine softening sciatic nerve bio-inspired neural prostheses neuroscientific research bidirectional LED chip microfluidic device electrode-tissue interface impedance intracortical silicon carbide three-dimensional bias micro-electromechanical systems (MEMS) silicon neural probes electrode degradation chronic microelectrode biocompatibility optogenetics fast-scan cyclic voltammetry (FSCV) glial encapsulation deep brain stimulation electrocorticography electrophysiology fast scan cyclic voltammetry precision medicine microfabrication BRAIN Initiative polymer magnetic resonance imaging polymer nanocomposite liquid crystal elastomer silicon probe training tissue response graphene electrode glassy carbon electrode immune response electrode implantation dextran immunohistochemistry neural interface response amorphous silicon carbide Utah electrode arrays neural amplifier neural electrode array neuromodulation in vivo electrophysiology neuronal recordings neural recording ECoG gene modification neural interface wireless enteric nervous system cellulose nanocrystals |
| ISBN | 3-03921-320-2 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Neural Microelectrodes |
| Record Nr. | UNINA-9910367568503321 |
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Pancrazio Joseph
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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New Aspects of Cancer Stem Cell Biology : Implications for Innovative Therapies
| New Aspects of Cancer Stem Cell Biology : Implications for Innovative Therapies |
| Autore | Cavallaro Ugo |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (208 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
Cadherin 11
WNT signaling β-catenin cancer stem cells TNBC early breast cancer bevacizumab neoadjuvant chemotherapy ALDH1 solid cancer chemo-resistance HDAC inhibitors head and neck squamous cell carcinoma SRC dasatinib saracatinib EC-8042 Ovarian cancer Wnt signaling tumor progression therapy resistance exosomes oral cancer risk oral epithelial dysplasia SOX2 immunohistochemistry oral squamous cell carcinoma genome-wide transcriptome lung cancer ATAC-seq RNA-seq CSCs NSCLC B4GALT1 LUAD breast cancer lipid metabolism therapeutic resistance bowel cancer organoid tumoroid colorectal colon stem cell chemotherapy resistance ovarian cancer cancer stem cell genetic heterogeneity SNP array L1CAM chemoresistance epithelial-mesenchymal transition cancer therapy cell adhesion molecule |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | New Aspects of Cancer Stem Cell Biology |
| Record Nr. | UNINA-9910557112003321 |
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Cavallaro Ugo
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Oligodendrocyte Physiology and Pathology Function
| Oligodendrocyte Physiology and Pathology Function |
| Autore | Kipp Markus |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (330 p.) |
| Soggetto topico |
Medicine
Neurosciences |
| Soggetto non controllato |
plasma membrane proteins
liquid chromatography-mass spectrometry murine acute brain slices reproducibility rat cerebellum Nsun5 Williams-Beuren syndrome (WBS) corpus callosum (CC) oligodendrocyte (OL) myelination remyelination EGFR inhibitor smoothened agonist microfibers drug screening multiple sclerosis cuprizone atrophy design-based stereology 18F-FDG macromolecular proton fraction MPF myelin magnetic resonance imaging cuprizone model demyelination oligodendrocyte precursors oligodendrocytes immunohistochemistry oligodendrocyte epigenetics neurodegeneration laquinimod energy drinks caffeine taurine neuron OPC oligodendrocyte progenitor cells screening nanofibers DigiGait™ experimental autoimmune encephalomyelitis gait analysis schizophrenia interneuron pluripotent stem cells cognition treatment cre-recombinase experimental autoimmune encephalomyelitis (EAE) glial progenitor cells tamoxifen down syndrome white matter glial fate transient receptor potential ankyrin 1 astrocyte conditional knockout astrocytes white matter disease cross-talk CNS glial cells age microglia |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557760203321 |
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Kipp Markus
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Pheochromocytoma (PHEO) and Paraganglioma (PGL)
| Pheochromocytoma (PHEO) and Paraganglioma (PGL) |
| Autore | Pacak Karel |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (380 p.) |
| Soggetto non controllato |
polycythemia
peptide receptor radiotherapy vasculogenesis catecholamines neuroendocrine GTV adaptive immunity therapy resistance histology transgenic mice cryoablation spheroids energy metabolism somatostatinoma angiogenesis pheochromocytoma SDHD percutaneous ethanol injection metanephrines SDHB global longitudinal strain mutation normetanephrines catecholamine PASS PGL 177Lu-DOTATATE chromosomal alteration speckle-tracking echocardiography lL-6 dog percutaneous ablation stem-like tumor cells EPAS1 neural crest fluorescence imaging neutrophil xenograft inflammation head and neck weighted standard deviation FGF21 calorimetry HIF average real variability next-generation sequencing adrenocortical carcinoma carotid body hypoxia-inducible factor paraganglioma succinate dehydrogenase blood pressure variability arrhythmia mortality NF1 toll-like receptor GAPP NET subclinical systolic dysfunction pheochromocytoma and paraganglioma PET-CT pan-cancer analysis mouse pheochromocytoma cells innate immunity neurogenesis neuroendocrine tumor obesity hypotension hypoxia CNV detection 18F-FDOPA comparative genomics adrenomedullary function PCC pathogen-associated molecular patterns adrenal tumor radiotherapy 11C-hydroxy-ephedrine radiofrequency ablation PPGL minimally invasive procedure sporadic diabetes mellitus adrenal incidentaloma germline mutation immunotherapy VHL immunohistochemistry metastatic OR malignant pheochromocytoma erythropoietin postoperative targeted therapy PRRT metastatic mitochondria T cell TCA cycle meta-analysis pseudohypoxia ectopic secretion radiosensitization chromogranin A hereditary hypertension PET phosphorylation tyrosine hydroxylase |
| ISBN | 3-03921-655-4 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Pheochromocytoma |
| Record Nr. | UNINA-9910367743903321 |
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Pacak Karel
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Placental Related Disorders of Pregnancy
| Placental Related Disorders of Pregnancy |
| Autore | Mistry Hiten D |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (378 p.) |
| Soggetto topico |
Medicine
Physiology |
| Soggetto non controllato |
low-dose aspirin
preeclampsia placenta eicosanoids sphingolipids thromboxane prostacyclin isoprostanes neutrophils protease-activated receptor 1 cold shock protein intrauterine growth restriction placentation apoptosis NF-κB hypertension in pregnancy angiogenesis endothelial function oxidative stress antioxidants post-maturity senescence pre-eclampsia renin-angiotensin system megalin proton pump inhibitors telomere shortening prenatal depression sex differences flow culture system explant culture under flow placental insufficiency SPINT2/HAI-2 foetal growth restriction small for gestational age placentome pregnancy nutrient restriction gene expression transcriptome spontaneous preterm birth bioenergetic metabolism interactome fetal sex disparity CD24 cytotrophoblast syncytiotrophoblast immunohistochemistry quantitative polymerase chain reaction (qPCR) immune tolerance inflammation cytokines adipokines antimicrobial peptides metabolic stress IGF-I insulin lactotroph hormones decidual reaction fetal membranes placental hormones primates uterine spiral artery uterine NK cell chorionic somatomammotropin blood flow nutrient uptake uterus ERAP2 trophoblast cells RNA sequencing differentially expressed genes congenital heart disease hand1 vascular development intrahepatic cholestasis of pregnancy human placenta bile acids transporters pregnancy complications metabolism glycolysis mitochondrial respiration placental metabolism trophoblast glycolysis trophoblast mitochondrial respiration sexual dimorphism Interleukin-15 CD122 natural killer cells macrophages trophoblast Irisin TRPV6 calcium transport skeletal dysplasia serine proteases subunit assembly transient receptor potential antioxidant capacity decidua fetal growth restriction KEAP1 NRF2 |
| ISBN | 3-0365-5899-3 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910639995303321 |
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Mistry Hiten D
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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