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Novel Treatment Strategies for Glioblastoma
| Novel Treatment Strategies for Glioblastoma |
| Autore | Stylli Stanley |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (268 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
glioblastoma
glioma temozolomide radiotherapy immunotherapy novel therapy personalized treatment drug repurposing invasion invadopodia ion channels gene therapy viral vectors brain tumor nanomedicine cancer stem cell targeted therapy brain cancer cell cycle differentiation proliferation RAS SRGAP2 stem cell TP53 glioblastoma multiforme GBM nerve/glial antigen 2 NG2 CK2 CX-4945 migration CRISPR/Cas9 anticancer anti-angiogenesis thyrointegrin αvβ3 PEG triazole tetrac P-bi-TAT P-m-TAT tetrac one-carbon metabolism de novo purine synthesis metabolic reprogramming metabolic treatment vaccine immune checkpoint inhibitors chimeric antigen receptor (CAR) T cells glioblastoma (GB) prolyl-oligopeptidase (POP) vascular endothelial growth factor (VEGF) transforming growth factor-β (TGF-β) angiopoietin (Ang) endothelial nitric oxide synthase (eNOS) newly diagnosed glioblastoma recurrent glioblastoma new trial design drug-inducible gene expression Mardepodect Regorafenib drug targets tumor antigens renin-angiotensin system pluripotent stem cells organoids cancer stem cells cancer stem cell niche tumor microenvironment |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557363703321 |
Stylli Stanley
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Precision Medicine in Solid Tumors
| Precision Medicine in Solid Tumors |
| Autore | Dey Nandini |
| Pubbl/distr/stampa | Basel, : MDPI Books, 2022 |
| Descrizione fisica | 1 electronic resource (304 p.) |
| Soggetto topico |
Medicine
Oncology |
| Soggetto non controllato |
pediatric tumors
tumor mutational burden TMB whole-exome sequencing gene panel sequencing immune checkpoint inhibitors glioblastoma prognosis overall survival extent of resection random forest Decision tree personalized precision oncology circulating free DNA liquid biopsy epidermal growth factor receptor tyrosine kinase inhibitor osimertinib comprehensive genomic profiling molecular genotyping intratumor heterogeneity multiple biopsies tumor evolution clonality classification strategic therapeutic intervention thymoma driver mutation sequencing molecular barcoding EGFR mutation EGFR-TKI cfDNA NGS digital enrichment next-generation sequencing solid cancer universal health-care system precision medicine presumed germline findings clinical guideline non-small cell lung cancer outcome adjuvant chemotherapy anaplastic lymphoma receptor tyrosine kinase HNSCC ctDNA tDNA DDR genes PARP inhibitors new drug development next-generation sequencing (NGS) open data regulatory reform tumor profiling test triple-negative breast cancer (TNBC) breast cancer targeted therapy TNBC subtypes immunotherapy cancer screening smoking electronic records PD-L1 cancer-associated fibroblasts resistance chemotherapy CTC immunocytochemistry parallel double-detection laboratory-friendly |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910595078103321 |
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Dey Nandini
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| Basel, : MDPI Books, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Recent Advances in Antibody Therapeutics
| Recent Advances in Antibody Therapeutics |
| Autore | Heo Yong-Seok |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (238 p.) |
| Soggetto topico |
Research & information: general
Chemistry |
| Soggetto non controllato |
interleukin 33
ST2 receptor scFv C2_2E12 bladder cancer antibodies immune checkpoint inhibitors antibody-drug conjugates sacituzumab govitecan enfortumab vedotin erdafitinib cost-effectiveness G protein-coupled receptor membrane protein antigen therapeutic antibody anti-angiogenesis delta-like ligand irinotecan paclitaxel VEGF SARS-CoV-2 spike protein receptor-binding domain phage display monoclonal antibody cytomegalovirus peptide/major histocompatibility complex class I complex T-cell-receptor-like antibody affinity maturation yeast surface display combinatorial antibody library agonist antibody cell fate bispecific antibodies bioassays mechanisms of action binding assays potency assays atherosclerosis inflammation antibody therapy blood-brain barrier antibody pharmacokinetics disposition biochemical and physicochemical properties Fc binding receptor-mediated transcytosis brain shuttle molecular Trojan horse transferrin anti-cancer antibody antibody engineering biophysical properties computational methods research cell bank antibody therapeutics recombinant antibodies intracellular antibodies single-chain antibody fragment nanobody Human papillomaviruses HPV oncoproteins HPV-associated cancer HPV cancer therapy asthma refractory asthma biomarker |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910580204803321 |
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Heo Yong-Seok
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Recent Developments on Protein–Ligand Interactions : From Structure, Function to Applications
| Recent Developments on Protein–Ligand Interactions : From Structure, Function to Applications |
| Autore | de Brevern Alexandre G |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (282 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences Biochemistry |
| Soggetto non controllato |
pimaricin thioesterase
protein-substrate interaction macrocyclization molecular dynamics (MD) simulation pre-reaction state folate folate receptor peptide conjugation click reaction biolayer interferometry acetylcholinesterase resistance organophosphorus pesticides molecular modeling lepidopterous insects conserved patterns similarity 3D-patterns epigenetics protein-RNA interaction RRM domain inhibitor NMR fragment-based screening TDP-43 galectin-1 gulopyranosides fluorescence polarization benzamide selective phospholipase C gamma 1 SLP76 virtual screening pharmacophore mapping molecular docking molecular dynamics caspase inhibition protein-ligand binding free energy Monte Carlo sampling docking and scoring molecular conformational sampling procollagen C-proteinase enhancer-1 glycosaminoglycans computational analysis of protein-glycosaminoglycan interactions calcium ions fragment-based docking protein–ligand analysis drug discovery and design structure–activity relationships bioremediation High Energy Molecules HMX protein design nitroreductase flavoprotein substrate specificity pharmacophore secretoglobin odorant-binding protein chemical communication pheromone N-phenyl-1-naphthylamine in silico docking protein–ligand interactions 2D interaction maps ligand-binding assays protein-ligand complexes dataset clustering structural alignment refinement PD-1/PD-L1 immune checkpoint inhibitors biphenyl-conjugated bromotyrosine amino acid conjugation amino-X in silico simulation IC50 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti |
Recent Developments on Protein–Ligand Interactions
Recent Developments on ProteinâLigand Interactions |
| Record Nr. | UNINA-9910566462703321 |
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de Brevern Alexandre G
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Renal Cell Carcinoma
| Renal Cell Carcinoma |
| Autore | López José I |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (500 p.) |
| Soggetto topico |
Renal cell carcinoma
Kidneys - Cancer |
| Soggetto non controllato |
N-glycomapping
SMAD proteins patient survival pro-IL-1? survival prediction inflammation markers tumor migration prognostic factors practical approach circular RNAs in a clinico-genomic predictive model glycomarkers review nephrectomy uric acid VEGF inhibitors metabolic reprogramming collecting duct carcinoma curcumin metabolome profiling identification of circular RNAs IL-2 experimental validation of circular RNA Raf/MEK/ERK HOT PI3K/Akt/mTOR pentose phosphate pathway kidney cancer LOT mutation RCC polybromo-1 pale cell MMP-9 gene expression recurrence free survival chromosomal loss IL-1? chronic kidney disease glutathione transferase omega 2 label-free glutathione transferase omega 1 emerging entity copy number alteration FOXO3 predictive role tumor slice culture tyrosine kinase inhibitors PPP ESC CDKN1A expression metastasis PD-L1 diagnostic and prognostic markers EVI1 copy number loss RNA sequencing NK cells glutathione metabolism clear cell renal cell carcinoma renal cell cancer proliferation eosinophilic variant Xp11 translocation renal cell carcinoma prognosis invasion immune infiltration IL4R? FISH 11) translocation renal cell carcinoma tumor microenvironment metabolome hyperosmolality toxicity ALK drug sensitivity t(6 copy number analysis urine genetic association polymorphism solute carrier proteins kidney metastatic ccRCC molecular genetic features recurrence-free survival chromophobe renal cell carcinoma unclassified renal tumor overall survival mTOR inhibitors mTOR JAK2 von Hippel-Lindau miR-155-5p glycoproteomics PBRM1 miR-133b survival TFE3 TFEB oncocytic renal tumor immune checkpoint inhibitors biomarker MMP10 TCGA ghrelin EMT like checkpoint inhibitors MiT family translocation renal cell carcinoma gene signature sarcomatoid transforming growth factor beta clear cell Renal Cell Carcinoma tumor adhesion renal cancer unclassified renal cell carcinoma Papillary renal cell carcinoma (pRCC) miR-146a-5p renal cell everolimus integrins cytoreductive nephrectomy immunotherapy predictive factors immunohistochemistry MTA2 IL13R?1 targeted therapy intratumour heterogeneity aurora A TCA cycle AMP-activated protein kinases cancer-specific survival programmed death-ligand 1 efficacy renal cell carcinoma anaplastic lymphoma kinase rearrangement TFEB-amplified renal cell carcinoma statins cancer immunotherapy microRNA new entity proteome profiling |
| ISBN | 3-03928-639-0 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910404087003321 |
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López José I
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| MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Role of Medical Imaging in Cancers . Volume 1
| Role of Medical Imaging in Cancers . Volume 1 |
| Autore | Fanti Stefano |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (312 pages) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
positron emission tomography
head and neck neoplasms neovascularization pathologic PET/CT urothelial carcinoma bladder cancer upper tract urothelial carcinoma survival PET PSMA prostate DCFPyL DCFBC PSMA-1007 ovarian cancer relapse SUVmax targeted therapy prognosis soft tissue sarcoma (STS) pazopanib dynamic 18F-FDG PET/CT SUV two-tissue compartment model magnetic resonance imaging machine learning diffusion perfusion texture analysis squamous cell carcinoma of the head and neck diffusion-weighted imaging malignant pleural mesothelioma pleural dissemination empyema pleural effusion mCRPC SPECT/CT Computer-assisted diagnosis XOFIGO Therapy response assessment circulating miRNAs breast cancer imaging parameters PET/MRI biomarkers triple negative breast cancer VCAM-1 SPECT imaging sdAbs Hounsfield unit computed tomography adipose tissue precision oncology FDG-PET/CT PERCIST metastatic breast cancer prostate cancer 18F-FACBC recurrence meta-analysis review meningioma somatostatin receptor neuroimaging radionuclide therapy breast imaging marker radiomics Yin Yang 1 PDAC Mesothelin noninvasive imaging receptor status molecular imaging nuclear medicine guidelines overutilization epistemology consensus mantle cell lymphoma 18F-FDG PET/CT Deauville criteria Radium-223 FDG castrate resistant prostate cancer programmed cell death 1 receptor diagnostic imaging CTLA-4 Antigen Immunotherapy Adoptive radioactive tracers radionuclide imaging CD8-Positive T-Lymphocytes PI-RADS diffusion kurtosis imaging dynamic contrast-enhanced magnetic resonance imaging 68Gallium-PSMA PET/CT prostate-specific-antigen PSA kinetics thresholds biochemical recurrence optimal cutoff level non-small-cell lung cancer circulating tumor cells immunotherapy response to treatment head and neck cancer HPV EBV p16 Molecular imaging miRNA expression radiogenomics radiomic diagnosis biomarker glioblastoma radiation therapy MRI diffusion tensor imaging Hodgkin lymphoma diffuse large B-cell lymphoma staging response assessment locally advanced cervical cancer concurrent chemoradiotherapy treatment response follow up cystic tumor International Consensus Guidelines intraductal papillary mucinous neoplasms pancreatic neoplasms PD-1 PD-L1 response to therapy NSCLC positron-emission tomography single-photon emission computed tomography immune checkpoint inhibitors gold nanoparticle heat shock protein 70 spectral-CT |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557432103321 |
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Fanti Stefano
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Role of Medical Imaging in Cancers . Volume 2
| Role of Medical Imaging in Cancers . Volume 2 |
| Autore | Fanti Stefano |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (228 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
positron emission tomography
head and neck neoplasms neovascularization pathologic PET/CT urothelial carcinoma bladder cancer upper tract urothelial carcinoma survival PET PSMA prostate DCFPyL DCFBC PSMA-1007 ovarian cancer relapse SUVmax targeted therapy prognosis soft tissue sarcoma (STS) pazopanib dynamic 18F-FDG PET/CT SUV two-tissue compartment model magnetic resonance imaging machine learning diffusion perfusion texture analysis squamous cell carcinoma of the head and neck diffusion-weighted imaging malignant pleural mesothelioma pleural dissemination empyema pleural effusion mCRPC SPECT/CT Computer-assisted diagnosis XOFIGO Therapy response assessment circulating miRNAs breast cancer imaging parameters PET/MRI biomarkers triple negative breast cancer VCAM-1 SPECT imaging sdAbs Hounsfield unit computed tomography adipose tissue precision oncology FDG-PET/CT PERCIST metastatic breast cancer prostate cancer 18F-FACBC recurrence meta-analysis review meningioma somatostatin receptor neuroimaging radionuclide therapy breast imaging marker radiomics Yin Yang 1 PDAC Mesothelin noninvasive imaging receptor status molecular imaging nuclear medicine guidelines overutilization epistemology consensus mantle cell lymphoma 18F-FDG PET/CT Deauville criteria Radium-223 FDG castrate resistant prostate cancer programmed cell death 1 receptor diagnostic imaging CTLA-4 Antigen Immunotherapy Adoptive radioactive tracers radionuclide imaging CD8-Positive T-Lymphocytes PI-RADS diffusion kurtosis imaging dynamic contrast-enhanced magnetic resonance imaging 68Gallium-PSMA PET/CT prostate-specific-antigen PSA kinetics thresholds biochemical recurrence optimal cutoff level non-small-cell lung cancer circulating tumor cells immunotherapy response to treatment head and neck cancer HPV EBV p16 Molecular imaging miRNA expression radiogenomics radiomic diagnosis biomarker glioblastoma radiation therapy MRI diffusion tensor imaging Hodgkin lymphoma diffuse large B-cell lymphoma staging response assessment locally advanced cervical cancer concurrent chemoradiotherapy treatment response follow up cystic tumor International Consensus Guidelines intraductal papillary mucinous neoplasms pancreatic neoplasms PD-1 PD-L1 response to therapy NSCLC positron-emission tomography single-photon emission computed tomography immune checkpoint inhibitors gold nanoparticle heat shock protein 70 spectral-CT |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557309503321 |
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Fanti Stefano
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Small Cell Lung Cancer: A New Era Is Beginning?
| Small Cell Lung Cancer: A New Era Is Beginning? |
| Autore | Morabito Alessandro |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (150 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
immune checkpoint inhibitors
extensive-stage small cell lung cancer nivolumab ipilimumab pembrolizumab atezolizumab durvalumab chemotherapy small-cell lung cancer lobectomy pneumonectomy radiotherapy multimodal treatment immunotherapy SCLC PARP DDR ICB synthetic lethality SLFN11 STING pathology and classification of SCLC biology of SCLC immune-checkpoint inhibitors in SCLC small cell lung cancer Immunotherapy extensive disease lurbinectedin gene pathway pathobiology targeted therapy circulating tumor cells prognostic biomarker targeted agents |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Small Cell Lung Cancer |
| Record Nr. | UNINA-9910557380603321 |
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Morabito Alessandro
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Toxins and Cancer Therapy
| Toxins and Cancer Therapy |
| Autore | Snook Adam E |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (104 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
immunotoxin
ribotoxin α-sarcin RNase T1 furin intracellular trafficking colorectal cancer botulinum toxin botulinum neurotoxin cancer cancer cells neuropathic pain post-surgical pain parotid gland submaxillary gland gustatory hyperhidrosis sialocele parotid fistula immunotherapy vaccine immune checkpoint inhibitors adoptive cell therapy cytokine therapy Coley's Toxins glioblastoma drug discovery cytotoxic necrotizing factor type 1 protein purification recombinant protein production shiga toxins Gb3/CD77 apoptosis ER stress autophagy Burkitt lymphoma |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557123603321 |
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Snook Adam E
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Urological Cancer 2021
| Urological Cancer 2021 |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (328 pages) |
| Soggetto topico |
Research
Chemistry |
| Soggetto non controllato |
bladder cancer
radiotherapy radiosensitisation molecular subtypes preclinical studies bladder cancer cell lines latent cancer prostate cancer autopsy prognostic index prediction model mortality screening trial renal cell carcinoma PD-1 PD-L1 biomarkers immune checkpoint inhibitors prostatic neoplasms positron-emission tomography decision making tumor thrombus metastasectomy postoperative complications oncological outcomes radical cystectomy AHNAK2 prognosis dog comparative oncology inflammation prostatic atrophy preneoplastic lesion biomarker urine machine learning TRIPOD liquid biopsy glutaminase immunohistochemistry in situ methods prostate PSMA-RLT 177Lu-PSMA PSA mCRPC urinary bladder neoplasms Bacillus Calmette-Guérin (BCG) immunotherapy divergent differentiation variant morphology survival stereotactic body radiotherapy frail patients cancer metastasis genomic analysis microenvironment tumor ecology game theory fluorescence confocal microscopy prostate biopsy ablation margins focal therapy sphingosine 1-phosphate receptor 1 bladder carcinoma cell migration epithelial-mesenchymal transition FTY-720 OIP5 papillary renal cell carcinoma PLK1 tumorigenesis therapy image-guided magnetic resonance imaging ultrasonography biopsy abiraterone enzalutamide docetaxel novel hormonal therapies comparative effectiveness real-world treatment pattern metastatic prostate cancer epiplakin diagnosis advanced urothelial carcinoma immune checkpoint inhibitor prognostic tumour mutational board genomic signatures ctDNA inflammatory indices urothelial carcinoma frailty prognostic factor psoas muscle Hounsfield units |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910576872803321 |
| MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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