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Links between Fibrogenesis and Cancer: Mechanistic and Therapeutic Challenges: Mechanistic and Therapeutic Challenges
| Links between Fibrogenesis and Cancer: Mechanistic and Therapeutic Challenges: Mechanistic and Therapeutic Challenges |
| Autore | Gabazza Esteban C |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (348 p.) |
| Soggetto non controllato |
bleomycin
regeneration antitumor efficacy lung cancer SOX2 leiomyosarcoma lung cancer (LC) nanoparticles cytokines hepatocellular carcinoma metabolic reprogramming hepatic stellate cells angiogenesis transforming growth factor-? anaplastic lymphoma kinase idiopathic pulmonary fibrosis growth factor pathogenesis cancer-associated fibroblasts fibrosis lipopolysaccharide DHA lncRNA SREBP-1 YAP protein S non-small cell lung cancer (NSCLC) omega-3 fatty acid inflammation metastasis clinical symptoms miRNA smooth muscle tumor of uncertain malignant potential Wnt interstitial fluid pressure heterogeneity hepatocytes myometrium tumor necrosis factor ? tumor tumor microenvironment extracellular matrix TAZ carcinogenesis cystic formation pulmonary fibrosis HBV cytokine genetic instability diagnosis EMT crizotinib Hippo pathway GPR120 marker HCV non-alcoholic steatohepatitis pathology common pathways apoptosis type I collagen GPR40 acute lung injury uterine fibroid renal injury pathophysiology reactive oxygen species immunohistochemistry SMAD butylidenephthalide leiomyoma cirrhosis Erk1/2 targeted therapy TGF-? mechanotransduction therapy breast cancer hepatocellular carcinoma (HCC) hepatic stellate cells (HSCs) idiopathic pulmonary fibrosis (IPF) cancer-associated fibroblasts (CAFs) cancer signal pathway tumor stiffness |
| ISBN | 3-03921-707-0 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Links between Fibrogenesis and Cancer |
| Record Nr. | UNINA-9910367745903321 |
Gabazza Esteban C
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Marine Compounds and Cancer 2020
| Marine Compounds and Cancer 2020 |
| Autore | Honecker Friedemann |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (480 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
apoptosis
fucoidan hepatocellular carcinoma reactive oxygen species 3-alkylpyridinium polymers nicotine nicotinic acetylcholine receptor non-small cell lung carcinoma melanoma sinulariolide proteomic mitochondria caspase cascade marine fungus sediment anthranilic acid Penicillium paneum cytotoxicity dibromotyrosine mitochondrial dysfunction oxidative stress topoisomerase epigonal organ bonnethead shark Jurkat tumor cell line hippuristanol PEL AP-1 STAT3 Akt colorectal cancer marine mollusc brominated indoles shrimp chemoprevention fatty acids carotenoids cancer nanoparticle osteosarcoma lung metastasis elisidepsin lipid rafts hydroxylated lipids fatty acid 2-hydroxylase cooperative binding membrane permeabilization marine organisms polysaccharides anticancer anticarcinogenic mechanisms of action fumigaclavine C anti-proliferation mitochondrial pathway anti-cancer anti-proliferative carotenoid cell cycle arrest fucoxanthin azoxymethane bioactive natural product isatin in vivo model Marthasterias glacialis L. palmitic acid ER-stress CHOP Antibody Drug Conjugates (ADCs) marine antitumor agents clinical trials approved antitumor agents AD0157 angiogenesis marine drug pyrrolidinedione secondary metabolites cancer preventive chemopreventive trabectedin plitidepsin tumor-associated macrophages tumor microenvironment preclinical anticancer immunity antiangiogenesis fascaplysin cyclin-dependent kinase small cell lung cancer camptothecin poly(ADP-ribose)-polymerase inhibitor breast cancer seaweed therapeutic compounds autophagy marine drugs autophagy inhibitors autophagy inducers macrolide programmed cell death energy stress araguspongine C c-Met HER2 gemcitabine pazopanib phase I safety soft tissue sarcoma pachastrissamine jaspine B carbocyclic analogue sphingosine kinase inhibitor molecular modeling ET-743 DNA minor groove binder soft tissue sarcoma chemotherapy bis (2,3-dibromo-4,5-dihydroxy-phenyl)-methane (BDDPM) anti-metastatic activity cell adhesion β1-integrin FAK BEL-7402 cell triterpene glycosides sea cucumbers antitumor activities arrest of cell cycle antibacterial marangucyclines deep-sea Streptomyces sp. SCSIO 11594 LS-1 SNU-C5/5-FU TGF-β signaling carcinoembryonic antigen kalkitoxin Moorea producens mitochondria toxin VEGF angiogenesis inhibitor hypoxia-inducible factor-1 HIF-1 Lyngbya majuscula marine metabolites SZ-685C nonfunctioning pituitary adenomas Ecklonia cava phlorotannins dieckol migration sipholenol A ABC transporter multidrug resistance P-gp/ABCB1 BCRP/ABCG2 MRP1/ABCC1 marine natural products glioblastoma xyloketal B proliferation TRPM7 marine compound ribosomal protein genes snoRNA FAU RPS30 SNORA62 evolution Porifera Penicillium brevicompactum Brevianamide Mycochromenic acid derivative antifouling Caribbean sponge plakortide endoperoxide leukemia multi-drug resistant leukemia Sarcophyton ehrenbergi soft coral terpenes cembranoids cytotoxic activity molecular docking uveal melanoma oxidative stress virtual screening Topo I inhibitor low toxic natural product Ulva fasciata selenium-containing polysaccharide-protein complex pseudopterosin NF-κB p65 inflammation cytokine release IL-6 TNFα MCP-1 glucocorticoid receptor paulomycins Micromonospora antitumor Cantabrian Sea-derived actinobacteria puupehenones sponges antiangiogenic antitumoral porifera/sponge cancer genes molecular oncology bromophenol molecular mechanisms cell cycle PI3K/Akt p38/ERK ROS human lung cancer glycosaminoglycans antiproliferative heparan sulphate gliotoxin NSCLC adriamycin resistance Sepia ink polysaccharides antitumour chemosensitization anticoagulation sea anemone drug discovery endothelial cells RGD motif kunitz type inhibitor prostate cancer antioxidant natural marine compounds marine biotechnology microalgae marine sponges Aeroplysinin Isofistularin pheochromocytoma and paraganglioma metastasis cancer progression cell adhesion molecules integrin β1 hypoxia phycocyanin non-small cell lung cancer NF-κB signaling marine-derived drugs bioanalysis chromatography manzamine A epithelial-mesenchymal transition lung cancer circulating tumor cells signal transduction cisplatin Lampetra morii buccal gland cystatin F anti-angiogenesis cystatin superfamily Antimicrobial peptide (AMP) Tilapia piscidin 4 (TP4) non-small cell lung cancer (NSCLC) itampolin A FBDD p38α novel inhibitor tetracenomycin X cyclin D1 proteasomal degradation p38 c-JUN λ-carrageenan heparanase anticoagulant depolymerisation cell migration Aspergillus naphthopyrones endophytic fungus Leathesia nana mangrove-derived actinomycete ansamycins divergolides apoptosis-inducing activity actinomycin EMT invasion low molecular weight fucoidan extract N-Ras neuroblastoma-rat sarcoma Cancer programmed cell death-ligand 1 programmed cell death-ligand 2 human sarcoma cell line (HT1080 cells) human normal diploid fibroblast (TIG-1 cells) chimera chemical conjugation anticancer agent hybridization α9-nicotinic acetylcholine receptors (nAChRs) breast cancer cells αO-conotoxin GeXIVA targeted therapy gorgonian Leptogorgia humulane sesquiterpenoids anticancer activity 12-deacetyl-12-epi-scalaradial HeLa cells Nur77 MAPK/ERK pathway Mycalin A C15 acetogenins synthetic analogues antiproliferative activity A375 and HeLa cell lines polyoxygenated steroids sponge Haliclona gracilis Thalassia testudinum thalassiolin B polyphenols CYP1A1 benzo[a]pyrene JNK1/2 natural products synergism A549 cells cytoskeleton P2X7 receptor pollution anti-angiogenic gene expression HSP90 inhibitor |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557339303321 |
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Honecker Friedemann
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Marine Natural Products as Anticancer Agents
| Marine Natural Products as Anticancer Agents |
| Autore | Alves Celso |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (150 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
alga
marine-derived fungus Penicillium chrysogenum polyketide hydroxyphenylacetic acid cytotoxicity flaccidoxide-13-acetate hepatocellular carcinoma invasion migration epithelial-mesenchymal transition prostate cancer astaxanthin STAT3 proliferation colony formation apoptosis Sarcophyton digitatum biscembranoid-type metabolites inflammatory factor production LPS-stimulated murine macrophage Ehlich's tumor P. purpurogenum antitumor meroterpenoids inflammation T47D BT20 pontin mutp53 cancer stem cells Oct4 Nanog siRNA secondary metabolites epigenome epigenetic signaling bioactive compounds cancer therapy marine species environment total synthesis natural product nannocystin anti-cancer gram-scale aplysinopsin analogs indole alkaloids marine source chronic myeloid leukemia BH3 mimetics |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557595603321 |
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Alves Celso
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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MicroRNA and Cancer
| MicroRNA and Cancer |
| Autore | Tucci Paola |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (298 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
Breast cancer
Hypoxia inducible factor 1-alpha (HIF-1α) MicroRNA (miRNA) miR526b miR655 Oxidative stress Migration Cyclooxygenase-2 (COX-2) Prostaglandin E2 receptor 4 (EP4) PI3K/Akt adipokines endometrial cancer estrogens hyperinsulinemia insulin insulin resistance insulin signaling insulin-like growth factors microRNA miRNA ovarian cancer survival prognostic factor serum LDH blood biomarker circulating microRNA plasma immunotherapy immune checkpoint inhibitors metastatic melanoma hepatocellular carcinoma metastasis exosome bioinformatics analysis renal cancer RCC ccRCC meta-analysis miRNAs normal B-cell development B-CLL miRNA-transcription factor network regulation biomarker therapy prognosis diagnosis progression prediction smoking non-small cell lung cancer methylation miR-584-5p YKT6 snoRNA 2'-O-methylation pseudouridylation malignant melanoma cancer stem cell stemness head and neck squamous cell carcinoma colon cancer cancer stem cells microRNAs deformability PARP replication stress targeted therapy breast cancer circulating biomarkers medulloblastoma brain tumour subgroups stem cells |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910580213503321 |
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Tucci Paola
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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MicroRNA as Biomarkers in Cancer Diagnostics and Therapy
| MicroRNA as Biomarkers in Cancer Diagnostics and Therapy |
| Autore | Sempere Lorenzo F |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (166 p.) |
| Soggetto topico | MicroRNAs |
| Soggetto non controllato |
leukemia
cell lines hepatitis B virus long non coding RNA normalization of miRNA expression in RT-qPCR children colorectal review bevacizumab tumor budding cells oral cancer liquid biopsy hepatocellular carcinoma small t-antigen colorectal cancer protein-miRNA complex biomarkers biomarker interleukin-1? tissue analysis miRNAs T-cell acute lymphoblastic leukemia (T-ALL) leukoplakia inflammation exosomes circulating free DNA hepatitis C virus miRNA miR-21 extracellular microRNA endogenous controls lymphoma confocal slide scanning microscopy early diagnosis reference genes large T-antigen microRNA miRNA (microRNA) cancer TNF-? plasma |
| ISBN | 3-03921-250-8 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910346847003321 |
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Sempere Lorenzo F
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Molecular Pathways in Cancers
| Molecular Pathways in Cancers |
| Autore | Cristóbal Ion |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (284 p.) |
| Soggetto topico |
Medicine
Oncology |
| Soggetto non controllato |
actin cytoskeletal reorganization
breast cancer CD99 agonist EGFR dimerization endocytosis FAK dephosphorylation PTPN12 Rac1 RhoA tripeptide OMD PRELP tumor suppression gene bladder cancer initiation tight junction partial EMT tousled-like kinase (TLK) NIMA-related kinase 1 (NEK1) yes-associated protein 1 (YAP1) thioridazine (THD) MS-determined phosphopeptides human immunodeficiency virus type 1 epithelial cells carcinogenicity oxidative stress reactive oxygen species gp120 Tat Nef matrix protein p17 reverse transcriptase mitochondria metastasis OXPHOS cancer Warburg effect cancer therapeutics myeloproliferative neoplasms signaling pathways JAK2 CALR MPL TPOR DUSP1 MAPK Snail prostate cancer migration and invasion patient survival biomarkers pBRD4 SET PP2A prognosis triple negative breast cancer resistance anti-receptor therapy trastuzumab PI3K mTOR TAK-228 epigenetic methylation acetylation non-coding RNA small-cell lung cancer triple-negative breast cancer pancreatic ductal adenocarcinoma glioblastoma metastatic melanoma advanced ovarian cancer hepatocellular carcinoma immune evasion immunotherapy immune checkpoint inhibitors oncogenic signaling pathway molecular targeted agents genome epigenome tumor immune microenvironment ovarian cancer adaptive immunity innate immunity complement system cancer immunology tumor microenvironment splicing pathway luminal breast cancer BET inhibitors |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910566473703321 |
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Cristóbal Ion
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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New Therapies of Liver Diseases
| New Therapies of Liver Diseases |
| Autore | Toniutto Pierluigi |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (236 p.) |
| Soggetto topico | Public health & preventive medicine |
| Soggetto non controllato |
tolvaptan
cirrhotic ascites survival rate furosemide primary biliary cholangitis autoantibodies ursodeoxycholic acid treatment response second line therapy primary biliary cholangitis (PBC) primary sclerosing cholangitis (PSC) clinical trials ursodeoxycholic acid (UDCA) Farnesoid X Receptor (FXR) agonist Pan-Peroxisome Proliferator-Activated Receptor (PPAR) agonists liver cancer systemic treatment immunotherapy real-world unresectable hepatocellular carcinoma cirrhosis decompensation bleeding varices survival infection alcoholic hepatitis acute-on-chronic liver failure cholangiocarcinoma colorectal cancer metastases hepatocellular carcinoma liver transplantation Milan criteria alpha-fetoprotein solid organ transplantation liver injury immunosuppressant SARS-CoV-2 humoral response vaccination portal-systemic shunt ammonia vigilance HBV HDV antivirals functional cure pharmacology acute-on-chronic liver failure (ACLF) liver transplantation (LT) decompensated cirrhosis portal hypertension ascites non-selective beta-blockers TIPS rifaximin human albumin statins targeted therapy effective hypovolemia anti-mineralocorticoids loop diuretics vaptans |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910566457403321 |
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Toniutto Pierluigi
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Novel Biomarkers of Gastrointestinal Cancer
| Novel Biomarkers of Gastrointestinal Cancer |
| Autore | Shimura Takaya |
| Pubbl/distr/stampa | Basel, : MDPI Books, 2022 |
| Descrizione fisica | 1 electronic resource (248 p.) |
| Soggetto topico |
Medicine
Oncology |
| Soggetto non controllato |
colorectal cancer
advanced adenoma screening stool mRNA cancer screening cirrhosis AFP machine learning MALDI-TOF proteomics CXCR4 prognosis overall survival rectal cancer neoadjuvant chemoradiation mouse model biomarkers urokinase plasminogen activator (uPA) urokinase plasminogen activator receptor (uPAR) plasminogen activator inhibitor type 1 (PAI-1) circulating tumour cell (CTC) gastric cancer oesophageal cancer serine proteases tumour microenvironment serpins biomarker chemoresistance liquid biopsy microRNA long non-coding RNA colorectal neoplasms cancer screening tests early detection of cancer precision medicine unfolded protein hepatocellular cancer GSVA unfolded protein score epigenetic regulation genes somatic mutations molecular genetic markers extracellular vesicles microbiome 16S rRNA amplicon metagenomics liver fibrosis hepatocellular carcinoma recurrence SHG/TPEF microscopy artificial intelligence advanced gastric cancer targeted therapy urinary miRNA miR-129-1-3p miR-566 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910595076103321 |
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Shimura Takaya
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| Basel, : MDPI Books, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Nutraceutical, Nutrition Supplements and Human Health
| Nutraceutical, Nutrition Supplements and Human Health |
| Autore | Siddiqui Rafat A |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (348 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences Food & society |
| Soggetto non controllato |
Lactobacillus salivarius
otitis probiotic bacteriocin prevention Morus nigra L. black mulberry nutraceutical pharmacological properties coenzyme Q10 (CoQ10) bioavailability intestinal absorption neuroprotection fenugreek protein hydrolysate antiproliferative apoptosis antioxidant Caco2 cells catechins green tea extract herbal dietary supplements hepatotoxicity microbiome Streptococcus agalactiae GBS pregnancy cachexia plum cancer muscle wasting myoblasts protein synthesis graviola weight loss obesity blood glucose food composition metabolic syndrome natural products Carica papaya Bifidobacterium breve M-16V infant health clinical efficacy probiotics gut microbiota Autism spectrum disorder dietary supplements pediatric physician communication frankincense Boswellia boswellic acid lupeolic acid AKBA cytokine breast cancer pentacyclic triterpenic acid triterpenoid chorioallantoic membrane assay Platycodon grandiflorus root BMI body fat mass abdominal fat area wild rice metabolomics atherosclerosis LDL-r-KO mice cytokines 16S rDNA plasma feces proteins carbohydrates functional food curcumin formulated curcumin pharmacokinetics aurora kinase A hepatocellular carcinoma Dietary Supplement Label Database food description food classification FoodEx2 quelites supplementation arsenic vitamin K diet supplement age-related diseases vitamin K-dependent proteins pathological calcification inflammation skeletal muscles Bifidobacterium breve B-3 muscle mass mitochondria |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557507803321 |
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Siddiqui Rafat A
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Phospholipases: From Structure to Biological Function
| Phospholipases: From Structure to Biological Function |
| Autore | Balboa María A |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (348 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
inhibitor
metabolic stability α-methylation oxoesters phospholipase A2 adrenic acid arachidonic acid mass spectrometry lipid signaling inflammation monocytes/macrophages crotoxin snake venom lung impairment inflammatory response lipid mediators neuromuscular blocker lipidomics PAP-2 autotaxin lysophosphatidate G protein-coupled receptor PLA2G6 fatty liver phospholipid remodeling diet-induced obesity morbidly obesity choline and methionine deficiency glioblastoma sphingolipid sphingosine-1-phosphate sphingomyelinase sphingomyelin metastasis phosphatidic acid diacylglycerol lipin signaling cPLA2α psoriasis proliferation anti-inflammatory atherosclerosis phospholipases macrophages T cells lipins pancreatic islets β-cells insulin secretion glucose tolerance insulin resistance group VIA phospholipase A2 fatty acid knockout mouse lipid mediator lysophospholipid membrane phospholipid ceramide acidic sphingomyelinase neutral sphingomyelinase hepatocellular carcinoma alcoholic and nonalcoholic steatohepatitis preadipocytes prostaglandins adipokines cytokines EP receptors Group V phospholipase A2 lipids majeed syndrome LPIN2 LIPIN2 chronic non-bacterial osteomyelitis chronic recurrent multifocal osteomyelitis autoinflammatory inflammasome macrophage osteoclast |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Phospholipases |
| Record Nr. | UNINA-9910576879603321 |
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Balboa María A
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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