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Role of Stem Cells in Skeletal Muscle Development, Regeneration, Repair, Aging and Disease
| Role of Stem Cells in Skeletal Muscle Development, Regeneration, Repair, Aging and Disease |
| Autore | Pura Munoz-Canoves |
| Pubbl/distr/stampa | Frontiers Media SA, 2016 |
| Descrizione fisica | 1 electronic resource (220 p.) |
| Collana | Frontiers Research Topics |
| Soggetto non controllato |
ageing
satellite cell pericytes fibrosis myogenesis muscular dystrophies rejuvenation epigenetics muscle wasting sarcopenia |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910166645903321 |
Pura Munoz-Canoves
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| Frontiers Media SA, 2016 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Targeting Wnt Signaling in Cancer: Opportunities Abound If We Can Avoid the Sword of Damocles
| Targeting Wnt Signaling in Cancer: Opportunities Abound If We Can Avoid the Sword of Damocles |
| Autore | Kahn Michael |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (298 p.) |
| Soggetto topico |
Medicine
Pharmacology |
| Soggetto non controllato |
Wnt signaling
synovial sarcoma TNIK NCB-0846 MYC hepatitis B virus HBV cancer liver cancer β-catenin TCF/LEF pancreatic cancer pancreatic stellate cells CBP p300 pancreatitis fibrosis just-right signaling APC colorectal cancer RNA-binding proteins Musashi drug discovery Notch signaling cancer therapy fungi secondary metabolite derivative microenvironment Wnt AML drug target signaling colorectal porcupine R-spondin serrated immunotherapy wnt vitamin D colon cancer L1 Wnt target genes cell adhesion NF-κB invasion and metastasis cancer stem cells EMT Lgr5 Wnt/beta-catenin signaling angiogenesis anti-angiogenic therapy gastrointestinal cancers therapeutic targeting of Wnt signaling β-catenin paradox molecular targeting urothelial cancer immune checkpoint inhibitor immunotherapy resistance IBD colitis β-catenin mutations tumor metabolism tumor immunology molecular therapeutics precision medicine astrocytic brain tumors DKKs GSK3β |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Targeting Wnt Signaling in Cancer |
| Record Nr. | UNINA-9910566469503321 |
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Kahn Michael
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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The Role of Extracellular Matrix in Cancer Development and Progression
| The Role of Extracellular Matrix in Cancer Development and Progression |
| Autore | Tzanakakis George |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (182 p.) |
| Soggetto topico | Research & information: general |
| Soggetto non controllato |
elastin
ribosomal protein SA tongue carcinoma MMP-2 EGCG pancreatic ductal adenocarcinoma syndecans proteoglycans tumor progression angiogenesis syndecan-4 heparan sulfate cancer prognosis biomarker signal transduction proteoglycan metastasis extracellular matrix fibrosis immune cell modulation neutrophils neutrophil extracellular trap macrophages BCC MMP TIMP invasion lumican cancer cell growth motility hyaluronan RHAMM CD44 wound repair breast cancer malignant pleural mesothelioma pleural effusion extracellular vesicles biomarkers sulfated hyaluronan estrogen receptors epithelial-to-mesenchymal transition matrix metalloproteinases |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910566470803321 |
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Tzanakakis George
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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The Role of Fibrinolytic System in Health and Disease
| The Role of Fibrinolytic System in Health and Disease |
| Autore | Kwaan Hau C |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (170 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
COVID-19
fibrinolysis renin-aldosterone-angiotensin-system (RAAS) plasminogen activator inhibitor 1 (PAI-1) urokinase plasminogen activator urokinase plasminogen activator receptor plasminogen activator inhibitor-1 acute lung injury and repair and pleural injury and pleural organization PAI-1 cardiovascular disease cancer inflammation fibrosis aging obstructive sleep apnoea OSA coagulation platelets brown adipose tissue obesity plasminogen activation immune response thrombin activatable fibrinolysis inhibitor TAFI proCPU proCPB proCPR carboxypeptidase uPA uPAR PA system tissue-type plasminogen activator (tPA) urokinase-type plasminogen activator (uPA) neurodegeneration thrombin shear clot retraction Factor XIII clot stability NETs plasmin plasminogen activator PAI-2 antiplasmin |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910580213103321 |
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Kwaan Hau C
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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The Role of PPARs in Disease
| The Role of PPARs in Disease |
| Autore | Wagner Nicole |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (274 p.) |
| Soggetto topico |
Medicine
Physiology |
| Soggetto non controllato |
peroxisome-proliferator activated receptors
tumor angiogenesis tumor progression metastasis formation endothelial cells RNA sequencing PPARs toxicology pharmacology ligand vascular coronary artery lipidomics eicosanoids inflammation CYP450 peroxisome proliferator-activated receptor angiogenesis proliferation metastasis immortality resistance to cell death growth suppressors immune system cellular metabolism PPAR nuclear receptors addiction alcohol nicotine opioids psychostimulants animal models human studies Alzheimer’s risk factors PPARα lipids fatty acids modulators cognition sex therapy hypertrophic adipocytes PPARG isoforms PPARG splicing dominant-negative isoform in vitro adipocytes adipogenesis hypertrophic obesity insulin-resistance peroxisome proliferator-activated receptors (PPARs) synthetic agonists non-alcoholic fatty liver disease (NAFLD) non-alcoholic steatohepatitis (NASH) fibrosis Sirtuin1 peroxisome proliferator-activated receptor-γ coactivator-1α peroxisome proliferator activated receptors obesity metabolic syndrome vitamin B12 folate fetal programming inherited metabolic disorders PGC-1α, disease kidney cancer AKI CKD nephron PKD cilia cystogenesis ligands Alzheimer’s disease (AD) |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910566482503321 |
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Wagner Nicole
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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The Tight Junction and Its Proteins : More Than Just a Barrier
| The Tight Junction and Its Proteins : More Than Just a Barrier |
| Autore | Fromm Michael |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (432 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
tissue barrier
tight junction claudins tricellulin tight junctions organ preservation intestine transplantation ischemia intestinal mucosa lung epithelia interleukin 13 UBE2Z ubiquitin osmolality hydrostatic pressure cancer sensor tricellular tight junctions endometrial cancer epithelial barrier dysfunction Claudin-7 permeability WNK4 epithelial sodium channel (ENaC), collecting duct cells claudin-1 hydrogen peroxide phosphorylation claudin angulin drug development angubindin-1 Clostridium perfringens enterotoxin Clostridium perfringens iota-toxin antibody Mz-ChA-1 cells biliary epithelial cells phosphatidylcholine mucus paracellular transport atopic dermatitis cytokines STAT3 ZO-2 cholestasis gene transcription hypertrophy tumor suppressor NLS NES CaSR RhoA barrier function paracellular permeability antidiuretic hormone Claudin-14 CLDN14 hearing loss vestibular function cochlear implantation Hepatitis C Virus viral entry epidermal barrier reconstructed human epidermis claudin targeting Campylobacter jejuni curcumin apoptosis co-culture mouse colon TNF NFκB lipolysis-stimulated lipoprotein receptor (LSR) epithelial barrier cell–cell contact caspase kidney stones ion reabsorption quercetin brain barriers blood-brain barrier neurovascular unit blood-cerebrospinal fluid barrier arachnoid barrier glia limitans adherens junctions paracellular sodium transport thick ascending limb nephropathy HELIX syndrome hypokalemia hypermagnesemia anhidrosis gland dysfunction aging blood–brain barrier mutations kidney liver skin human mice disease in silico drug discovery membrane proteins protein interactions molecular dynamics antibiotic-associated hemorrhagic colitis Klebsiella oxytoca tight junction assembly monocytes celiac disease claudin-2 epithelium inflammation fibrosis proliferation migration tricellular tight junction paracellular water transport tight epithelium MDCK C7 cells cell growth endothelia adherens junction apical junctional complex AMP-activated protein kinase (AMPK) paracellular barrier protein structure protein domain occludin junctional adhesion molecule zonula occludens MAGUK proteins PDZ domain stem cell chemoresistance retinal pigment epithelium retinopathy barrier formation collecting duct claudin-5 neuropathic pain nerve injury dorsal root ganglion enteropathogenic E. coli (EPEC) tight junctions (TJ) polarity atypical aPKCζ transepithelial electrical resistance (TER) sorting nexin 9 (SNX9) EspF claudin 1 tumor metastasis epithelial to mesenchymal transition cerebral cavernous malformation endothelial barrier Rho ROCK MEKK3 ion transport ion channel super-resolution microscopy structured illumination microscopy stimulated emission depletion single molecule localization microscopy Claudin blood-biliary barrier chronic liver disease hepatocellular carcinoma cholangiocellular carcinoma NISCH syndrome repair NHE2 ClC-2 inflammatory bowel disease mucosal immunology ZO-1 actomyosin aquaporin drinking rate epithelial fluid transport enterocyte osmoregulation paracellular proximal tubule calcium permeability claudin-12 paracellular channels and barriers cell polarity pathogens immune cells environmental sensors |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Tight Junction and Its Proteins |
| Record Nr. | UNINA-9910557404603321 |
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Fromm Michael
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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The Tight Junction and Its Proteins: More Than Just a Barrier : More Than Just a Barrier
| The Tight Junction and Its Proteins: More Than Just a Barrier : More Than Just a Barrier |
| Autore | Fromm Michael |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (412 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
tissue barrier
tight junction claudins tricellulin tight junctions organ preservation intestine transplantation ischemia intestinal mucosa lung epithelia interleukin 13 UBE2Z ubiquitin osmolality hydrostatic pressure cancer sensor tricellular tight junctions endometrial cancer epithelial barrier dysfunction Claudin-7 permeability WNK4 epithelial sodium channel (ENaC), collecting duct cells claudin-1 hydrogen peroxide phosphorylation claudin angulin drug development angubindin-1 Clostridium perfringens enterotoxin Clostridium perfringens iota-toxin antibody Mz-ChA-1 cells biliary epithelial cells phosphatidylcholine mucus paracellular transport atopic dermatitis cytokines STAT3 ZO-2 cholestasis gene transcription hypertrophy tumor suppressor NLS NES CaSR RhoA barrier function paracellular permeability antidiuretic hormone Claudin-14 CLDN14 hearing loss vestibular function cochlear implantation Hepatitis C Virus viral entry epidermal barrier reconstructed human epidermis claudin targeting Campylobacter jejuni curcumin apoptosis co-culture mouse colon TNF NFκB lipolysis-stimulated lipoprotein receptor (LSR) epithelial barrier cell–cell contact caspase kidney stones ion reabsorption quercetin brain barriers blood-brain barrier neurovascular unit blood-cerebrospinal fluid barrier arachnoid barrier glia limitans adherens junctions paracellular sodium transport thick ascending limb nephropathy HELIX syndrome hypokalemia hypermagnesemia anhidrosis gland dysfunction aging blood–brain barrier mutations kidney liver skin human mice disease in silico drug discovery membrane proteins protein interactions molecular dynamics antibiotic-associated hemorrhagic colitis Klebsiella oxytoca tight junction assembly monocytes celiac disease claudin-2 epithelium inflammation fibrosis proliferation migration tricellular tight junction paracellular water transport tight epithelium MDCK C7 cells cell growth endothelia adherens junction apical junctional complex AMP-activated protein kinase (AMPK) paracellular barrier protein structure protein domain occludin junctional adhesion molecule zonula occludens MAGUK proteins PDZ domain stem cell chemoresistance retinal pigment epithelium retinopathy barrier formation collecting duct claudin-5 neuropathic pain nerve injury dorsal root ganglion enteropathogenic E. coli (EPEC) tight junctions (TJ) polarity atypical aPKCζ transepithelial electrical resistance (TER) sorting nexin 9 (SNX9) EspF claudin 1 tumor metastasis epithelial to mesenchymal transition cerebral cavernous malformation endothelial barrier Rho ROCK MEKK3 ion transport ion channel super-resolution microscopy structured illumination microscopy stimulated emission depletion single molecule localization microscopy Claudin blood-biliary barrier chronic liver disease hepatocellular carcinoma cholangiocellular carcinoma NISCH syndrome repair NHE2 ClC-2 inflammatory bowel disease mucosal immunology ZO-1 actomyosin aquaporin drinking rate epithelial fluid transport enterocyte osmoregulation paracellular proximal tubule calcium permeability claudin-12 paracellular channels and barriers cell polarity pathogens immune cells environmental sensors |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Tight Junction and Its Proteins |
| Record Nr. | UNINA-9910674057303321 |
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Fromm Michael
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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