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Marine Compounds and Cancer 2020
| Marine Compounds and Cancer 2020 |
| Autore | Honecker Friedemann |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (480 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
apoptosis
fucoidan hepatocellular carcinoma reactive oxygen species 3-alkylpyridinium polymers nicotine nicotinic acetylcholine receptor non-small cell lung carcinoma melanoma sinulariolide proteomic mitochondria caspase cascade marine fungus sediment anthranilic acid Penicillium paneum cytotoxicity dibromotyrosine mitochondrial dysfunction oxidative stress topoisomerase epigonal organ bonnethead shark Jurkat tumor cell line hippuristanol PEL AP-1 STAT3 Akt colorectal cancer marine mollusc brominated indoles shrimp chemoprevention fatty acids carotenoids cancer nanoparticle osteosarcoma lung metastasis elisidepsin lipid rafts hydroxylated lipids fatty acid 2-hydroxylase cooperative binding membrane permeabilization marine organisms polysaccharides anticancer anticarcinogenic mechanisms of action fumigaclavine C anti-proliferation mitochondrial pathway anti-cancer anti-proliferative carotenoid cell cycle arrest fucoxanthin azoxymethane bioactive natural product isatin in vivo model Marthasterias glacialis L. palmitic acid ER-stress CHOP Antibody Drug Conjugates (ADCs) marine antitumor agents clinical trials approved antitumor agents AD0157 angiogenesis marine drug pyrrolidinedione secondary metabolites cancer preventive chemopreventive trabectedin plitidepsin tumor-associated macrophages tumor microenvironment preclinical anticancer immunity antiangiogenesis fascaplysin cyclin-dependent kinase small cell lung cancer camptothecin poly(ADP-ribose)-polymerase inhibitor breast cancer seaweed therapeutic compounds autophagy marine drugs autophagy inhibitors autophagy inducers macrolide programmed cell death energy stress araguspongine C c-Met HER2 gemcitabine pazopanib phase I safety soft tissue sarcoma pachastrissamine jaspine B carbocyclic analogue sphingosine kinase inhibitor molecular modeling ET-743 DNA minor groove binder soft tissue sarcoma chemotherapy bis (2,3-dibromo-4,5-dihydroxy-phenyl)-methane (BDDPM) anti-metastatic activity cell adhesion β1-integrin FAK BEL-7402 cell triterpene glycosides sea cucumbers antitumor activities arrest of cell cycle antibacterial marangucyclines deep-sea Streptomyces sp. SCSIO 11594 LS-1 SNU-C5/5-FU TGF-β signaling carcinoembryonic antigen kalkitoxin Moorea producens mitochondria toxin VEGF angiogenesis inhibitor hypoxia-inducible factor-1 HIF-1 Lyngbya majuscula marine metabolites SZ-685C nonfunctioning pituitary adenomas Ecklonia cava phlorotannins dieckol migration sipholenol A ABC transporter multidrug resistance P-gp/ABCB1 BCRP/ABCG2 MRP1/ABCC1 marine natural products glioblastoma xyloketal B proliferation TRPM7 marine compound ribosomal protein genes snoRNA FAU RPS30 SNORA62 evolution Porifera Penicillium brevicompactum Brevianamide Mycochromenic acid derivative antifouling Caribbean sponge plakortide endoperoxide leukemia multi-drug resistant leukemia Sarcophyton ehrenbergi soft coral terpenes cembranoids cytotoxic activity molecular docking uveal melanoma oxidative stress virtual screening Topo I inhibitor low toxic natural product Ulva fasciata selenium-containing polysaccharide-protein complex pseudopterosin NF-κB p65 inflammation cytokine release IL-6 TNFα MCP-1 glucocorticoid receptor paulomycins Micromonospora antitumor Cantabrian Sea-derived actinobacteria puupehenones sponges antiangiogenic antitumoral porifera/sponge cancer genes molecular oncology bromophenol molecular mechanisms cell cycle PI3K/Akt p38/ERK ROS human lung cancer glycosaminoglycans antiproliferative heparan sulphate gliotoxin NSCLC adriamycin resistance Sepia ink polysaccharides antitumour chemosensitization anticoagulation sea anemone drug discovery endothelial cells RGD motif kunitz type inhibitor prostate cancer antioxidant natural marine compounds marine biotechnology microalgae marine sponges Aeroplysinin Isofistularin pheochromocytoma and paraganglioma metastasis cancer progression cell adhesion molecules integrin β1 hypoxia phycocyanin non-small cell lung cancer NF-κB signaling marine-derived drugs bioanalysis chromatography manzamine A epithelial-mesenchymal transition lung cancer circulating tumor cells signal transduction cisplatin Lampetra morii buccal gland cystatin F anti-angiogenesis cystatin superfamily Antimicrobial peptide (AMP) Tilapia piscidin 4 (TP4) non-small cell lung cancer (NSCLC) itampolin A FBDD p38α novel inhibitor tetracenomycin X cyclin D1 proteasomal degradation p38 c-JUN λ-carrageenan heparanase anticoagulant depolymerisation cell migration Aspergillus naphthopyrones endophytic fungus Leathesia nana mangrove-derived actinomycete ansamycins divergolides apoptosis-inducing activity actinomycin EMT invasion low molecular weight fucoidan extract N-Ras neuroblastoma-rat sarcoma Cancer programmed cell death-ligand 1 programmed cell death-ligand 2 human sarcoma cell line (HT1080 cells) human normal diploid fibroblast (TIG-1 cells) chimera chemical conjugation anticancer agent hybridization α9-nicotinic acetylcholine receptors (nAChRs) breast cancer cells αO-conotoxin GeXIVA targeted therapy gorgonian Leptogorgia humulane sesquiterpenoids anticancer activity 12-deacetyl-12-epi-scalaradial HeLa cells Nur77 MAPK/ERK pathway Mycalin A C15 acetogenins synthetic analogues antiproliferative activity A375 and HeLa cell lines polyoxygenated steroids sponge Haliclona gracilis Thalassia testudinum thalassiolin B polyphenols CYP1A1 benzo[a]pyrene JNK1/2 natural products synergism A549 cells cytoskeleton P2X7 receptor pollution anti-angiogenic gene expression HSP90 inhibitor |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557339303321 |
Honecker Friedemann
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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New Trends and Applications in Femtosecond Laser Micromachining
| New Trends and Applications in Femtosecond Laser Micromachining |
| Autore | Vázquez Rebeca Martínez |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (158 p.) |
| Soggetto topico |
Research & information: general
Physics Optical physics |
| Soggetto non controllato |
ultrafast laser microfabrication
microfluidic glass bonding ultrashort laser pulses heat accumulation transparent materials quartz stealth dicing femtosecond fused silica double pulses selective chemical etching cell elasticity endothelial cells optical micromanipulation holographic optical tweezers two-photon polymerization image processing micromodels porous media 3D multi-depth channels laser machining femtosecond laser micromachining femtosecond laser material processing micro/nanotechnology fabrication atomic force microscope laser ablation diameter separation distance (SW) sub-micron bridges YBCO thin film photonic quantum chip femtosecond laser direct writing Hadamard gate CNOT gate path-encoded Bell state femtosecond laser fs-assisted cataract surgery laser-assisted ophthalmic surgery high pulse frequency low energy roughness analysis thermal annealing integrated optics glass micromachining 3D structuring |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910566480803321 |
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Vázquez Rebeca Martínez
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Platelets and Immune Responses during Thromboinflammation
| Platelets and Immune Responses during Thromboinflammation |
| Autore | Schattner Mirta |
| Pubbl/distr/stampa | Frontiers Media SA, 2020 |
| Descrizione fisica | 1 electronic resource (169 p.) |
| Soggetto topico |
Medicine
Immunology |
| Soggetto non controllato |
platelets
thromboinflammation neutrophils endothelial cells inflammation sepsis cancer |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557767203321 |
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Schattner Mirta
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| Frontiers Media SA, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Role of Genomics in the Management of Hypertension
| Role of Genomics in the Management of Hypertension |
| Autore | Mulatero Paolo |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (200 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
atrial natriuretic peptide
T2238C variant endothelial dysfunction smooth muscle cells contraction platelet aggregation epigenetics cardiovascular diseases renin low-renin hypertension mineralocorticoid receptor genetics aldosterone essential hypertension blood pressure genome-wide association studies exome microarray next-generation sequencing rare variants rare-variants association testing burden test sequence kernel association test hypokalemia low renin hypertension monogenic hypertension Liddle syndrome SCNN1A SCNN1B SCNN1G non-coding RNA micro RNA primary aldosteronism aldosterone-producing adenoma transcriptome profiing DNA methylation histone modifications vascular smooth muscle cells endothelial cells Kruppel-like factor 15 left ventricular hypertrophy cardiac hypertrophy heart failure genetics of left ventricular hypertrophy fibromuscular dysplasia non atherosclerotic vascular stenosis PHACTR1 genetic association cervical artery dissection spontaneous coronary arteries dissection CRY1 CRY2 HSD3B1 HSD3B2 cardio-tonic steroids endogenous ouabain adducin renal damage African American ARMC5 GRK4 CACNA1D endocrine hypertension |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557741603321 |
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Mulatero Paolo
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Roles and Functions of ROS and RNS in Cellular Physiology and Pathology
| Roles and Functions of ROS and RNS in Cellular Physiology and Pathology |
| Autore | Zarkovic Neven |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (230 p.) |
| Soggetto non controllato |
toxicity
toll-like receptors acrolein hydroxyapatite-based biomaterials LC-MS/MS blood–brain barrier NADPH-oxidase human neuroblastoma SH-SY5Y cells NRF2-NQO1 axis granulocytes free radicals antioxidant plaque vulnerability bEnd.3 relaxation Ca2+ keratinocytes oxidative metabolism of the cells lipid peroxidation intermittent hypoxia osteoblast growth UV radiation ROS bEnd5 cyclopurines NF?B glucose deprivation antimicrobial endothelial cells 4-hydroxynonenal (4-HNE) histamine glutamine deprivation optical coherence tomography antioxidants DNA damage glutathione NQO1 transcript variants xeroderma pigmentosum cancer cells VAS2870 reactive oxygen species (ROS) TP53 mutation DNA and RNA polymerases viability oxidative burst macrophages inflammation Nrf2 von Willebrand factor reactive oxygen species growth control intracellular signaling MFN2 nuclear factor erythroid 2–related factor 2 fusion/fission IMR-90 calcium proliferation mitochondria pathophysiology of oxidative stress redox balance 4-hydroxynonenal cannabidiol oxidative homeostasis rs1800566 neuronal cell death heme-oxygenase-1 vitamins cell signaling TRPM2 channel aorta cancer growth cancer regression oxidative stress nucleotide excision repair |
| ISBN | 3-03928-783-4 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910404087603321 |
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Zarkovic Neven
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| MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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State-of-Art in Innate Immunity
| State-of-Art in Innate Immunity |
| Autore | Fischer Silvia |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (188 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
inflammation
type I interferons interleukin-1β crosstalk hepatic non-parenchymal cells albumin chronic liver diseases bacteria cytomegalovirus endothelin receptor repurposing cell culture Drosophila suzukii hemocytes plasmatocytes extracellular traps HMGB1 RAGE TLR4 DAMP SIRT1 α7-nicotinic acetylcholine receptor nociceptor cancer COVID-19 proteostasis autoinflammation ribosomopathies proteinopathies proteasomopathies extracellular RNA cytokines macrophages endothelial cells toll-like receptors angiogenesis γδ T cells gamma delta T cells proliferation macrophage polarization neutrophils neutrophil extracellular traps NETs ischemia PANoptosis PANoptosome pyroptosis apoptosis necroptosis inflammatory cell death inflammasome innate immunity infection NLR caspase IRF1 ZBP1 RIPK1 RIPK3 MLKL NLRP3 AIM2 Pyrin caspase-1 ASC caspase-8 caspase-3 caspase-7 plasticity redundancy SMOC1 thrombin |
| ISBN | 3-0365-5324-X |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910619465003321 |
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Fischer Silvia
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| MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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The Pathogenetic Mechanisms at the Basis of Aortopathy Associated with Bicuspid Aortic Valve: Insights from "Omics", Models of Disease and Emergent Technologies
| The Pathogenetic Mechanisms at the Basis of Aortopathy Associated with Bicuspid Aortic Valve: Insights from "Omics", Models of Disease and Emergent Technologies |
| Autore | Alessandro Della Corte |
| Pubbl/distr/stampa | Frontiers Media SA, 2018 |
| Descrizione fisica | 1 electronic resource (170 p.) |
| Collana | Frontiers Research Topics |
| Soggetto non controllato |
smooth muscle cells
microRNAs aortic root endothelial cells aortic surgery bicuspid aortic valve 4DFlow analysis aortopathy |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Pathogenetic Mechanisms at the Basis of Aortopathy Associated with Bicuspid Aortic Valve |
| Record Nr. | UNINA-9910345964103321 |
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Alessandro Della Corte
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| Frontiers Media SA, 2018 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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The Role of PPARs in Disease
| The Role of PPARs in Disease |
| Autore | Wagner Nicole |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (274 p.) |
| Soggetto topico |
Medicine
Physiology |
| Soggetto non controllato |
peroxisome-proliferator activated receptors
tumor angiogenesis tumor progression metastasis formation endothelial cells RNA sequencing PPARs toxicology pharmacology ligand vascular coronary artery lipidomics eicosanoids inflammation CYP450 peroxisome proliferator-activated receptor angiogenesis proliferation metastasis immortality resistance to cell death growth suppressors immune system cellular metabolism PPAR nuclear receptors addiction alcohol nicotine opioids psychostimulants animal models human studies Alzheimer’s risk factors PPARα lipids fatty acids modulators cognition sex therapy hypertrophic adipocytes PPARG isoforms PPARG splicing dominant-negative isoform in vitro adipocytes adipogenesis hypertrophic obesity insulin-resistance peroxisome proliferator-activated receptors (PPARs) synthetic agonists non-alcoholic fatty liver disease (NAFLD) non-alcoholic steatohepatitis (NASH) fibrosis Sirtuin1 peroxisome proliferator-activated receptor-γ coactivator-1α peroxisome proliferator activated receptors obesity metabolic syndrome vitamin B12 folate fetal programming inherited metabolic disorders PGC-1α, disease kidney cancer AKI CKD nephron PKD cilia cystogenesis ligands Alzheimer’s disease (AD) |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910566482503321 |
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Wagner Nicole
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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