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Molecular Psychiatry
| Molecular Psychiatry |
| Autore | Rein Theo |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (288 p.) |
| Soggetto topico |
Medicine
Mental health services |
| Soggetto non controllato |
cardiovascular disease
cell adhesion molecules immunology inflammation nervous system schizophrenia bipolar disorder major depressive disorder DNA methylation response variability antipsychotics drug design multi-target drugs polypharmacology multi-task learning machine learning biomarker discovery psychiatry serotonin 5-HT 4 receptor 5-HT4R depression mood disorder expression Alzheimer's disease cognition Parkinson's disease forced swimming Roman rat lines stress hippocampus BDNF trkB PSA-NCAM western blot immunohistochemistry general cognitive function intelligence GWAS genetic correlation childhood-onset schizophrenia (COS) induced pluripotent stem cell (iPSC) copy number variation (CNV) early neurodevelopment neuronal differentiation synapse dendritic arborization miRNAs stress physiology cytoskeleton actin dynamics DRR1 TU3A FAM107A acid sphingomyelinase alcohol dependence liver enzymes sphingolipid metabolism withdrawal Hsp90 GR stress response steroid hormones molecular chaperones psychiatric disease circadian rhythms FKBP51 FKBP52 CyP40 PP5 DISC1 neurodevelopment CRMP-2 proteomics antidepressant treatment HPA axis gene expression FKBP5 sleep sleep EEG biomarkers antidepressants cordance gender sex difference antidepressant rapid-acting Ketamine endocrinology (2R,6R)-Hydroxynorketamine electroconvulsive therapy basic-helix-loop-helix brain coactivator glucocorticoids mineralocorticoid receptor knockout transcription biology dopaminergic gene polymorphisms affective temperament obesity alpha-synuclein SNCA major depression Hamilton Scale of Depression chemokines neuroinflammation social defeat Immune response T cells susceptibility resilience Treg cells Th17 cells behavior PPARγ |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557793503321 |
Rein Theo
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Novel Natural-based Biomolecules Discovery for Tackling Chronic Diseases
| Novel Natural-based Biomolecules Discovery for Tackling Chronic Diseases |
| Autore | Kwok Hang Fai |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (180 p.) |
| Soggetto topico |
Humanities
Social interaction |
| Soggetto non controllato |
DAPK1
SUMO SENP protein degradation post-translational modification amphibian Bowman-Birk inhibitor Tat peptide molecular cloning antifungal drug design protease inhibitor natural-based compound anticancer therapy lung cancer survivin apoptosis STAT3 colorectal cancer orientin cell cycle arrest Bcl-2 family proteins Astragalus membranaceus insulin PI3K AKT PPARγ PDX-1 Petasites japonicus Asteraceae lignan anti-inflammation NO PGE2 iNOS COX-2 molecular docking peptides kynurenines binding affinity μ-opioid receptor pharmacophore G-protein activation fucoidan PLGA docetaxel drug delivery system anticancer therapy/cancer treatment hIAPP amyloidogenesis insulin granules endoplasmic reticulum anionic lipids F23R variant β-sheet transitions β-cell cytotoxicity unfolded protein response pomegranate punicalagin tannins gingiva fibroblasts antioxidant wound healing branched-chain fatty acids Conidiobolus heterosporus peroxisome proliferator-activated receptor α lipid metabolism fatty acid oxidation hepatocyte |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557607403321 |
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Kwok Hang Fai
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Novel Strategies in the Development of New Therapies, Drug Substances and Drug Carriers
| Novel Strategies in the Development of New Therapies, Drug Substances and Drug Carriers |
| Autore | Kutner Andrzej |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (450 p.) |
| Soggetto topico |
Research & information: general
Chemistry |
| Soggetto non controllato |
alpha-ketoglutarate
cell cycle apoptosis JNK cell migration cell invasion TGF-β VEGF glycoconjugates methotrexate cancer treatment glucose metabolism drug design and discovery anticancer drugs targeted therapy Warburg effect antidepressants pyrido[1,2-c]pyrimidines dual 5-HT1A/SERT activity drug design anticancer activity lung cancer resveratrol PRI-2191 vitamin D active substance delivery systems biomedical hydrogels active substance-controlled release genistein hydrogels for cosmetology hydrogels for dermatology transdermal active substance delivery systems histone deacetylase (HDAC) depression biomarker anti-depressant therapy human DNA topoisomerase cancer drug molecular docking synthesis fluorine vitamin D3 metabolite A-ring CD-ring side-chain nanoparticles molecular modeling oxidation mechanisms electrochemistry MALDI spectroscopic data cytotoxic study self-assembled monolayer gold electrode multimodal activity calcium-sensing receptor enantiomer calcimimetic calcilytic colon cancer stereospecificity HT-29 IL-8 inflammation cyclooxygenase 1,2,4-triazole pyridazinone SAR anti-inflammatory activity antioxidant activity ADME anticancer drug antimicrobial peptide (AMP) dermaseptin frog skin peptides LHRH prostate cancer Phyllomedusa bicolor therapeutic peptides copper (II) complexes thiourea cytotoxic activity proteome analysis antimicrobial activity major latex protein Chelidonium majus greater celandine defense-related proteins alkaloids cancer cells vitamin D receptor split luciferase-based biosensor CYP24A1-dependent metabolism CYP27B1 rickets genome editing vitamin D biology and action transcription ChIP-chip analysis distal enhancers histone H3 acetylation RNA polymerase II analogue actions at genes vitamin D hormone (1,25(OH)2D3) latex antiviral proteins antimicrobial compounds cytotoxicity drug discovery CRISPR/Cas9 tetrahydro-β-carbolines Plasmodium falciparum (P. falciparum) antimalarial antiparasitic agents hemolysis vitamin D analogs 25 vitamin D 24-hydroxylase CYP24A1 proliferation high-grade serous ovarian cancer cells gold Au(III) complex colorectal cancer organometallic cancer therapy metallodrugs |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910585938903321 |
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Kutner Andrzej
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Venom and Toxin as Targeted Therapy
| Venom and Toxin as Targeted Therapy |
| Autore | Kwok Hang Fai (Henry) |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (180 p.) |
| Soggetto non controllato |
cane toad
B cell non-Hodgkin lymphoma Malaysian cobras complement system decay accelerating factor neuroblastoma atopic dermatitis complement dependent cytotoxicity antioxidant enzymes bacterial adhesion cancer therapy N. kaouthia anuran skin secretion frog Apis mellifera syriaca solid phase extraction bee venom phospholipase A2 (bvPLA2) disintegrin toad toxins immunotoxins ribosome-inactivating proteins antimicrobial peptide (AMP) drug design Moxetumomab pasudotox snake venom antiviral activity in vitro effects bombesin-related peptide oxidative stress biomarkers half-life blood vessel formation target therapy 2 MYCN indolealkylamines Huachansu membrane attack complex bouganin bee venom SEM anticancer activity antimicrobial peptide house dust mite extract (DFE) mannose receptor O. hannah bicarinalin gastric cells melittin LC-ESI-MS dermaseptin smooth muscle apoptosis anticancer N. sumatrana Helicobacter pylori inflammation immunotherapy atopic dermatitis (AD) immunotoxin mantle cell lymphoma clearance mass spectrometry Bougainvillea rRNA N-glycosylase activity fungal toxin skin inflammation targeted therapy 4-dinitrochlorobenzene (DNCB) Bee venom VEGF Chansu bufadienolides obsessive-compulsive disorder (OCD) BLF1 antimicrobial activity orellanine VB6-845 acute lymphoblastic leukemia ribosome-inactivating protein CD206 molecular cloning cancer CD22 eIF4A |
| ISBN | 3-03921-190-0 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910367754703321 |
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Kwok Hang Fai (Henry)
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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