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Precise Genome Editing Techniques and Applications
| Precise Genome Editing Techniques and Applications |
| Autore | Zhang Zhiying |
| Pubbl/distr/stampa | Frontiers Media SA, 2020 |
| Descrizione fisica | 1 electronic resource (135 p.) |
| Soggetto topico |
Science: general issues
Medical genetics |
| Soggetto non controllato |
precise genome editing
CRISPR HDR efficiency biallelic HDR targeting off-target effect animal model base editing |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557218603321 |
Zhang Zhiying
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| Frontiers Media SA, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Preventing Developmental Brain Injury – From Animal Models to Clinical Trials
| Preventing Developmental Brain Injury – From Animal Models to Clinical Trials |
| Autore | Tsuji Masahiro |
| Pubbl/distr/stampa | Frontiers Media SA, 2019 |
| Descrizione fisica | 1 electronic resource (316 p.) |
| Soggetto topico |
Medicine
Neurology & clinical neurophysiology |
| Soggetto non controllato |
neonatal encephalopathy
Brain Injury prematurity and low birth weight animal model clinical study |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557464003321 |
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Tsuji Masahiro
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| Frontiers Media SA, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Radiopharmaceuticals for PET Imaging - Issue A
| Radiopharmaceuticals for PET Imaging - Issue A |
| Autore | Roivainen Anne |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (212 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
kinetic analysis
Siglec-9 gallium-68 vascular adhesion protein VAP-1 infection inflammation osteomyelitis animal model Staphylococcus aureus multiple myeloma positron emission tomography/computed tomography radiopharmaceuticals 18F-fluorodeoxyglucose tetrazine ligation PET SPECT indium-11 fluorine-18 positron emission tomography (PET), defluorination isotopic exchange silicon-based fluoride acceptor bioorthogonal chemistry tetrazine inverse electron-demand Diels-Alder ligation opioid naloxone overdose fentanyl carfentanil [11C]carfentanil positron emission tomography receptor occupancy pharmacokinetics [18F]AlF NOTA NODAGA PODS thiol-reactive linker affibody molecule bioconjugation EGFR tumor imaging vulnerable plaque molecular imaging PET imaging nanobody single-domain antibody sub-millimetre resolution AlF-radiolabelling preclinical radiopharmaceutical dosimetry image-based internal dosimetry OLINDA MCT1/MCT4 lactate transporter inhibitor [18F]FACH radiation safety sigma-1 receptor availability orthotopic xenograft of glioblastoma in mouse small animal Positron Emission Tomography/Magnetic Resonance Imaging (PET/MRI) (S)-(−)-[18F]fluspidine imaging-based biomarker SV2A protein PET radiotracers synaptic loss radiochemistry preclinical development clinical outcomes monocarboxylate transporters (MCTs) FACH 18F-labeled analog of FACH α-CCA blood-brain barrier (BBB) positron emission tomography (PET) imaging peptides proteolysis metabolic stability |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557437003321 |
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Roivainen Anne
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Recent Developments and Applications in Tissue Mechanics and Tissue Engineering
| Recent Developments and Applications in Tissue Mechanics and Tissue Engineering |
| Autore | Boschetti Federica |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (82 p.) |
| Soggetto topico |
Technology: general issues
Chemical engineering |
| Soggetto non controllato |
abdominal aortic aneurysm
biaxial testing mechanical properties in vivo strain wall shear stress inflammation regional variations heterogeneity Goldmann tonometry intraocular pressure glaucoma inflation tests pig eyes corneal stiffness retina tissue engineering retina regeneration biofabrication 3D bioprinting electrospinning ophthalmology hematopoietic CD34 progenitor stem cells microencapsulation chitosan alginate proliferation megakaryocyte animal model dermal regeneration Integra Matriderm skin substitute wound healing |
| ISBN | 3-0365-5318-5 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910619469703321 |
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Boschetti Federica
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| MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Recent Studies of Rodent Ultrasonic Vocalizations and Their Use in Experimental Models
| Recent Studies of Rodent Ultrasonic Vocalizations and Their Use in Experimental Models |
| Autore | Brudzynski Stefan M |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (352 p.) |
| Soggetto topico |
Medicine
Neurosciences |
| Soggetto non controllato |
ultrasonic vocalization
maternal immune activation autism communication rat sex differences social play rats anxiety observational fear learning USV maternal separation pup vasopressin antagonists righting reflex negative geotaxis ACTH corticosterone Brattleboro rat larynx female male 50-khz ultrasonic vocalizations (USVs) individual differences chronic variable stress (CVS) dopamine nucleus accumbens microdialysis evolution of vocalization 22 kHz calls 50 kHz calls infant isolation calls emotional arousal mesolimbic dopaminergic system mesolimbic cholinergic system hedonia ultrasonic vocalizations cognitive development respiration brain oscillations Cav1.2 calcium animal model rough-and-tumble play social approach playback social contact call alarm call social buffering distress emotional contagion fear contagion aversive state automated scoring addiction mental health machine learning drug discovery drug development Parkinson's disease alpha-synuclein 6-OHDA Pink1 DJ1 exercise pharmacology pathology hypervigilance hyperreactivity exaggerated reactivity generalization PTSD depression heart rate Wistar 22-kHz calls 50-kHz calls affect aversion NOR reward working memory Y maze opioids fentanyl self-administration play food dam-pup interaction ethanol pup isolation rat pup 50 kHz vocalizations 22 kHz vocalizations amphetamine chemogenetics clozapine-n-oxide UMAP males females vocalizations fear extinction pain |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557608903321 |
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Brudzynski Stefan M
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Spumaretroviruses
| Spumaretroviruses |
| Autore | Khan Arifa |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (352 p.) |
| Soggetto topico |
Medicine
Neurosciences |
| Soggetto non controllato |
spumavirus
feline illness proviral load neglected virus bovine foamy virus infectious clone particle release cell-free transmission foamy virus spumaretrovirus cross-species virus transmission zoonosis restriction factors immune responses FV vectors virus replication latent infection feline foamy virus epidemiology retrovirus Spumaretrovirus mountain lion Puma concolor ELISA protease reverse transcriptase RNase H reverse transcription antiviral drugs resistance simian foamy virus gibbon lesser apes co-evolution complete viral genome equine foamy virus isolation Japan sero-epidemiology reptile foamy virus endogenous foamy virus endogenous retrovirus ancient retroviruses co-speciation foamy virus-host interactions viral tropism infection kidney cats chronic kidney disease chronic renal disease integrase integration co-infections NHP pathogenesis zoonoses viral prevalence Neotropical primates free-living primates Brazil new world primates simian retrovirus BFV spuma virus model system animal model animal experiment miRNA function gene expression antiviral host restriction gene therapy in-vivo gene therapy hematopoietic stem and progenitor cells foamy virus vector pre-clinical canine model SCID-X1 innate sensing cGAS STING foamy viruses wild ruminants European bison red deer roe deer fallow deer seroreactivity inter-species transmission HSC gene marking FV gene transfer to HSCs gene therapy alternatives serotype high-throughput sequencing replication kinetics cytopathic effect reverse transcriptase activity miRNA expression virus-host-interaction miRNA target gene identification innate immunity ANKRD17 Bif1 (SH3GLB1) replication in vitro |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557409103321 |
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Khan Arifa
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Structural and Functional Analysis of Extracts in Plants
| Structural and Functional Analysis of Extracts in Plants |
| Autore | Lamponi Stefania |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (465 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
hierarchical cluster analysis
principal component analysis ultrasound-assisted extraction triterpenic acid Ziziphus jujuba water-pepper FRAP DPPH polarity-based solvent extraction α-amylase inhibition circular economy green biorefinery polyunsaturated fatty acids phytochemicals amino acids food and feed UHPLC-ESI-ORBITRAP-MS/MS Bergenia emeiensis polysaccharides optimization RSM acrylamide-induced damage Sorbus commixta fruit anti-melanoma activity caspase-3 polyphenolic compounds depression antioxidant cytokines anti-inflammatory cytotoxicity medicinal mushroom Psilocybe natalensis coak oak chlorophyll terpenes lupeol cuticular permeance Suaeda vermiculata halophyte aqueous-ethanolic extract liver toxicity hepatoprotective liver disorders mass spectrometry LC-MS HepG-2 HepG-2/ADR zebrafish toxicity embryotoxicity medicinal plant animal model Crocus sativus in vivo carrageenan analgesic antidepressant anticoagulant adipogenesis AMPK anti-obesity triglycerides UCP1 Anacardiaceae design of experiments (DOEs) flavonoids green extraction HPLC-DAD LC-MS/MS tannins ultrasound assisted-extraction (UAE) compact mass spectrometry cleansing properties detergent plants phytochemical tissue culture Arbutus pavarii antibacterial activity MRSA time-kill curves ultrahigh-performance liquid chromatography mass spectrometry (UHPLC- ESI-MS/MS) Trigonella stellata caffeic acid osteoporosis osteoblast osteoclast BMP Euphorbia cuneata Euphorbiaceae lipopolysaccharide oxidative stress NF-κB lung injury pachycereus weberi escontria chiotilla antioxidant activity phenolic compounds betalains food composition food analysis Scrophularia buergeriana S. koraiensis S. takesimensis harpagoside osteoclast differentiation RANKL Araucaria angustifolia bioactive compounds cysteine protease inhibitor functional food insecticide plant extracts termites tumor cells pine nuts urban pest polyphenols fruit development natural food colorant Sambucus canadensis Japanese knotweed Reynoutria Polygonum Polygonaceae anthraquinones emodin physcion HPTLC HPTLC-MS densitometry carrot juices carotenoids high-speed juicer low-speed juicer food processing extraction glucosinolates kale (Brassica oleracea var. acephala) phenolics candelilla plant antioxidant properties antimicrobial activity candelilla cultivation candelilla wax polysterols saponins therapeutic properties sage stirring and heating extraction mechanochemical extraction antiproliferative activity mutagenicity anticoagulant activity Rosmarinus officinalis hydroalcoholic extract Sam-Myo-Whan traditional medicine gouty arthritis inflammation monosodium urate Underutilized Mexican plants Cactus fruits Antioxidant activities Antiproliferative properties |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557474303321 |
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Lamponi Stefania
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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The Physiological Functions of the Amyloid Precursor Protein Gene Family
| The Physiological Functions of the Amyloid Precursor Protein Gene Family |
| Autore | Ulrike C. Muller |
| Pubbl/distr/stampa | Frontiers Media SA, 2017 |
| Descrizione fisica | 1 electronic resource (275 p.) |
| Collana | Frontiers Research Topics |
| Soggetto non controllato |
Amyloid precursor-like protein
learning and memory neuroprotection spines synaptic plasticity Alzheimers disease animal model synaptogenesis synaptic adhesion Amyloid precursor protein |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910261133303321 |
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Ulrike C. Muller
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| Frontiers Media SA, 2017 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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