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State-of-Art in Innate Immunity
| State-of-Art in Innate Immunity |
| Autore | Fischer Silvia |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (188 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
inflammation
type I interferons interleukin-1β crosstalk hepatic non-parenchymal cells albumin chronic liver diseases bacteria cytomegalovirus endothelin receptor repurposing cell culture Drosophila suzukii hemocytes plasmatocytes extracellular traps HMGB1 RAGE TLR4 DAMP SIRT1 α7-nicotinic acetylcholine receptor nociceptor cancer COVID-19 proteostasis autoinflammation ribosomopathies proteinopathies proteasomopathies extracellular RNA cytokines macrophages endothelial cells toll-like receptors angiogenesis γδ T cells gamma delta T cells proliferation macrophage polarization neutrophils neutrophil extracellular traps NETs ischemia PANoptosis PANoptosome pyroptosis apoptosis necroptosis inflammatory cell death inflammasome innate immunity infection NLR caspase IRF1 ZBP1 RIPK1 RIPK3 MLKL NLRP3 AIM2 Pyrin caspase-1 ASC caspase-8 caspase-3 caspase-7 plasticity redundancy SMOC1 thrombin |
| ISBN | 3-0365-5324-X |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910619465003321 |
Fischer Silvia
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| MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Stem Cell Research on Cardiology
| Stem Cell Research on Cardiology |
| Autore | David Robert |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (356 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
Fabry disease
human embryonic stem cells CRISPR/Cas9 genomic editing Mass spectrometry proteomic analysis hypertrophic cardiomyopathy disease model physical exercise cardiac cellular regeneration microRNA (miR) Akt signaling cardiomyocyte proliferation cardiac hypertrophy cardioprotection myocarditis inflammation leukocytes cardiomyocytes multi-electrode-array micro-electrode-array MEA drug/toxicity screening field potential arrhythmia electrocardiography cardiac regeneration stem cells iPSC PSC ESC cardiovascular disease regeneration cardiac progenitor cells induced pluripotent stem cells transdifferentiation direct reprogramming genetic engineering cardiac tissue engineering biomaterials 18F-FDG PET cardiac induced cells cardiac function non-invasive imaging human pluripotent stem cell ventricular maturation bone marrow stem cells angiogenesis myocardial infarction human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) iPS cells big conductance calcium activated potassium channel (BK) Maxi-K slo1 KCa1.1 iberiotoxin long QT syndrome mesenchymal stromal cells (MSC) mRNA miRNA cardiac reprogramming cardiac differentiation cardiovascular diseases adult stem cells myocardial infraction 3D printing 3D model bioprinting cardiovascular medicine heart myocardium heart valves vascular graft endothelialization tissue engineering decorin fibronectin electrospinning endothelial progenitor cells bioreactor biostable polyurethane MicroRNA Mir-133 coronary heart disease biomarker meta-analysis |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557701803321 |
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David Robert
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Sulfur-Containing Marine Bioactives
| Sulfur-Containing Marine Bioactives |
| Autore | Palumbo Anna |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (140 p.) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
propylene glycol alginate sodium sulfate
angiogenesis invasion FGF2 MMP-2 MMP-9 fucoidan fucan age-related macular degeneration VEGF oxidative stress Laminaria hyperborea brown seaweed extracts proliferation molecular weight retinal pigment epithelium thiopeptide antibiotic screening structure elucidation natural products rare actinobacteria carbohydrate sulfotransferase carrageenan cytochrome P450 galactose-6 sulfurylase red alga reproduction stages WD 40 sulfavants adjuvant immunomodulatory activity colloid aggregates algae antioxidant diatoms light nitric oxide ovothiol biofouling marine coatings anti-settlement chemical synthesis sulfated gallic acid eco-friendly Tetraselmis suecica autotrophic culture heterotrophic culture exopolysaccharides antioxidant capacity cytotoxic effects on tumor cells |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557113603321 |
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Palumbo Anna
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Targeting Angiogenesis to Treat Autoimmune Diseases and Cancer
| Targeting Angiogenesis to Treat Autoimmune Diseases and Cancer |
| Autore | Amit Rahat Michal |
| Pubbl/distr/stampa | Frontiers Media SA, 2020 |
| Descrizione fisica | 1 electronic resource (119 p.) |
| Soggetto topico |
Medicine
Immunology |
| Soggetto non controllato |
angiogenesis
autoimmunity semaphorins MMPs EMMPRIN TRPs YKL-39 VEGF |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557791103321 |
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Amit Rahat Michal
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| Frontiers Media SA, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Targeting Wnt Signaling in Cancer: Opportunities Abound If We Can Avoid the Sword of Damocles
| Targeting Wnt Signaling in Cancer: Opportunities Abound If We Can Avoid the Sword of Damocles |
| Autore | Kahn Michael |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (298 p.) |
| Soggetto topico |
Medicine
Pharmacology |
| Soggetto non controllato |
Wnt signaling
synovial sarcoma TNIK NCB-0846 MYC hepatitis B virus HBV cancer liver cancer β-catenin TCF/LEF pancreatic cancer pancreatic stellate cells CBP p300 pancreatitis fibrosis just-right signaling APC colorectal cancer RNA-binding proteins Musashi drug discovery Notch signaling cancer therapy fungi secondary metabolite derivative microenvironment Wnt AML drug target signaling colorectal porcupine R-spondin serrated immunotherapy wnt vitamin D colon cancer L1 Wnt target genes cell adhesion NF-κB invasion and metastasis cancer stem cells EMT Lgr5 Wnt/beta-catenin signaling angiogenesis anti-angiogenic therapy gastrointestinal cancers therapeutic targeting of Wnt signaling β-catenin paradox molecular targeting urothelial cancer immune checkpoint inhibitor immunotherapy resistance IBD colitis β-catenin mutations tumor metabolism tumor immunology molecular therapeutics precision medicine astrocytic brain tumors DKKs GSK3β |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Targeting Wnt Signaling in Cancer |
| Record Nr. | UNINA-9910566469503321 |
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Kahn Michael
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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The Retina in Health and Disease
| The Retina in Health and Disease |
| Autore | Ptito Maurice |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
| Descrizione fisica | 1 electronic resource (465 p.) |
| Soggetto topico |
Medicine
Neurosciences |
| Soggetto non controllato |
eye
retina development vascularization hypoxia autophagy programmed cell death cellular senescence retinogenesis altricial bird species precocial bird species senescence-associated galactosidase activity diabetes mellitus retinopathy microvascular complication optical coherence tomography angiography black African-American systemic disease biomarker retinal degenerative diseases mesenchymal stem cells stem cell therapy experimental models clinical trials AMD age-related macular degeneration trichostatin A (TSA) HDAC histone deacetylase vascular endothelial growth factor (VEGF) retinal degeneration endoplasmic reticulum stress response unfolded protein response GRP78 retinal glial cell diabetic retinopathy zebrafish neurovascular unit microvascular complications and dysfunction metabolism motor protein myosin 1C photoreceptor rhodopsin outer segments visual function macroglia astrocytes Müller cells optic nerve crush retinal ganglion cells spinal cord injury signal transducer and activator of transcription 3 epidermal growth factor Drp1 apoptosis mitochondria microglia neurodegeneration multiple sclerosis retinal microglia microglia morphotype light damage functional analysis early detection remodeling lactate GPR81 HCAR1 growth cone dLGN axon 3,5-DHBA kallikrein-kinin system kinin receptors GFAP osteopontin retinal detachment diabetes antioxidants bioenergetics respiration ATP glucagon-like peptide-1 exendin-4 catalase immunohistochemistry electron microscopy Charles Bonnet syndrome EEG visual hallucination resting state high-fat diet gut microbiome gut-retina axis RNA sequencing germ-free mice complement cascade angiogenesis retinal inflammation AII amacrine cell Prox1 parvalbumin gap junction eccentricity ON/OFF asymmetry arterioles betulinic acid ischemia-reperfusion injury reactive oxygen species retinal vessels retinal fluorescence imaging amyloid cognitive decline Alzheimer's disease optic neuritis oxidative stress neuroprotection fingolimod iPSC-RPE retinal pigment epithelium immunodeficient RCS rat ultrathin parylene retinal transplantation CD4+CD25+ inflammation iPSC typical cannabinoid receptors atypical cannabinoid receptors electroretinography monkeys visual system eye inflammation lipopolysaccharide natural bioactive extracts Ac2-26 FPR receptor inflammatory mediators retinal light injury LED screen optical filter retinal protection regeneration progenitor cell hyperglycemia photoreceptors neurod Notch |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557336603321 |
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Ptito Maurice
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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The Role of Extracellular Matrix in Cancer Development and Progression
| The Role of Extracellular Matrix in Cancer Development and Progression |
| Autore | Tzanakakis George |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (182 p.) |
| Soggetto topico | Research & information: general |
| Soggetto non controllato |
elastin
ribosomal protein SA tongue carcinoma MMP-2 EGCG pancreatic ductal adenocarcinoma syndecans proteoglycans tumor progression angiogenesis syndecan-4 heparan sulfate cancer prognosis biomarker signal transduction proteoglycan metastasis extracellular matrix fibrosis immune cell modulation neutrophils neutrophil extracellular trap macrophages BCC MMP TIMP invasion lumican cancer cell growth motility hyaluronan RHAMM CD44 wound repair breast cancer malignant pleural mesothelioma pleural effusion extracellular vesicles biomarkers sulfated hyaluronan estrogen receptors epithelial-to-mesenchymal transition matrix metalloproteinases |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910566470803321 |
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Tzanakakis George
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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The Role of PPARs in Disease
| The Role of PPARs in Disease |
| Autore | Wagner Nicole |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (274 p.) |
| Soggetto topico |
Medicine
Physiology |
| Soggetto non controllato |
peroxisome-proliferator activated receptors
tumor angiogenesis tumor progression metastasis formation endothelial cells RNA sequencing PPARs toxicology pharmacology ligand vascular coronary artery lipidomics eicosanoids inflammation CYP450 peroxisome proliferator-activated receptor angiogenesis proliferation metastasis immortality resistance to cell death growth suppressors immune system cellular metabolism PPAR nuclear receptors addiction alcohol nicotine opioids psychostimulants animal models human studies Alzheimer’s risk factors PPARα lipids fatty acids modulators cognition sex therapy hypertrophic adipocytes PPARG isoforms PPARG splicing dominant-negative isoform in vitro adipocytes adipogenesis hypertrophic obesity insulin-resistance peroxisome proliferator-activated receptors (PPARs) synthetic agonists non-alcoholic fatty liver disease (NAFLD) non-alcoholic steatohepatitis (NASH) fibrosis Sirtuin1 peroxisome proliferator-activated receptor-γ coactivator-1α peroxisome proliferator activated receptors obesity metabolic syndrome vitamin B12 folate fetal programming inherited metabolic disorders PGC-1α, disease kidney cancer AKI CKD nephron PKD cilia cystogenesis ligands Alzheimer’s disease (AD) |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910566482503321 |
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Wagner Nicole
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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The Role of Pregnancy Nutrition in Maternal and Offspring Health
| The Role of Pregnancy Nutrition in Maternal and Offspring Health |
| Autore | Maslova Ekaterina |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (320 p.) |
| Soggetto non controllato |
non-IgE-mediated food reactions
eating disorders foetal programming bulimia nervosa Obesity fatty fish Mediterranean diet angiogenesis pregnancy asthma preeclampsia infant nutrition food clusters placenta maternal nutrition DHA chronic kidney disease Dlx3 pregnancy outcomes neonatal outcomes choline offspring health sirtuin omega-3 inflammation placental insufficiency gestational diabetes docosahexaenoic acid fetal development birth weight binge eating disorder preterm Birth vitamin D food frequency questionnaire eating behavior attention deficit disorder with hyperactivity SGA systematic review weaning hypothalamic inflammation birthweight dietary screening food-related IgG breastfeeding purging preterm birth Rhodiola foetal growth micronutrients gestational age obesity prevention autism spectrum disorder vegan diets pregnancy nutrition Iodine nutritional programing dietary behaviour preterm labor nutrition birth length ghrelin lactation immunomodulators head circumference Echinacea dietary habits brain health probiotics Camellia large for gestational age (LGA) apoptosis vegetarian diets human milk anorexia nervosa neurodevelopmental disorders lifestyle intervention placental transport diet microglia Panax eye function plant-based diets social experiment meta-analysis essential fatty acids etiology small for gestational age (SGA) Insufficiency developmental origins of health and disease fortification |
| ISBN | 3-03921-997-9 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910367740303321 |
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Maslova Ekaterina
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Theme Issue Honoring Prof. Dr. Ludger Wessjohann’s 60th Birthday: Natural Products in Modern Drug Discovery
| Theme Issue Honoring Prof. Dr. Ludger Wessjohann’s 60th Birthday: Natural Products in Modern Drug Discovery |
| Autore | Hussain Hidayat |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (360 p.) |
| Soggetto topico |
Research & information: general
Chemistry Organic chemistry |
| Soggetto non controllato |
multi-component reaction
fusidic acid TEMPO-conjugate electron paramagnetic resonance (EPR) spectroscopy caspase-3 incomptine A sesquiterpene lactone Decachaeta incompta cytotoxic activity iTRAQ apoptosis ROS production violacein hepatocellular carcinoma proliferation stemness natural products tumor microenvironment (TME) lung cancer phytochemicals botanical agents steroidal alkaloids solanidane alkaloids demissidine solanidine flavonoids coronavirus SARS-CoV-2 SARS-CoV MERS-CoV anticancer activity apoptosis resistance ophiobolin A polygodial Wittig reaction melanoma tumor heterogeneity pregnancy anti-tumor peptides in vitro model medicinal herbs cancer treatment cancer stem cells drug resistance metastasis RCE-4 PCD ATG 4B the Bcl-2-Beclin 1 complex Sparticola junci structure elucidation ECD-TDDFT COX inhibitory molecular docking antiproliferative cytotoxic Sepedonium ampullosporum peptaibols ampullosporin glutamic acid methyl ester solid-phase peptide synthesis antifungal anticancer target identification kaempferol docking DARTS Src breast cancer butein frondoside-A STAT3 angiogenesis invasion viability tumor growth marine fungi Cosmospora sp soudanone Magnaporthe oryzae co-culture phytopathogen molecular networking metabolomics bispecific antibody Trypsiligase click chemistry biorthogonal chemistry antibody engineering |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Theme Issue Honoring Prof. Dr. Ludger Wessjohann’s 60th Birthday |
| Record Nr. | UNINA-9910585945403321 |
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Hussain Hidayat
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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