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Dual Specificity Phosphatases: From Molecular Mechanisms to Biological Function
| Dual Specificity Phosphatases: From Molecular Mechanisms to Biological Function |
| Autore | Pulido Rafael |
| Pubbl/distr/stampa | MDPI - Multidisciplinary Digital Publishing Institute, 2019 |
| Descrizione fisica | 1 electronic resource (240 p.) |
| Soggetto non controllato |
hematopoietic cells
DEPArray neuroblastoma liver steatosis MAPK phosphatase DUSP-4 granule neurons neuronal differentiation DUSP10 cytokines MAPKs single cell analysis macrophage asthma E. coli infection MAPK Cpp1 nucleotide receptors atypical DUSP RSV Pmp1 cannabinoids astrocytes sepsis influenza signaling triple-negative breast cancer (TNBC) differentiation HDAC6 (histone deacetylase isoform 6) atypical dual-specificity phosphatases microtubules respiratory viruses MK-STYX (MAPK (mitogen-activated protein kinase) phosphoserine/threonine/tyrosine-binding protein) dual-specificity phosphatase Msg5 TLR signaling mitogen-activated protein kinase fungal MKPs macrophages MAP Kinase Phosphatase-2 inflammation Sdp1 circulating tumor cells (CTCs) MAP kinases MAP kinase phosphatases P2X7 proliferation BDNF P2Y13 T cell hypertriglyceridemia integrated omics analysis post-translational modification rhinovirus protein stability ubiquitination dual-specificity phosphatases Mkp-1 cancer brain metastasis HER2 COPD pseudophosphatase |
| ISBN | 3-03921-689-9 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Dual Specificity Phosphatases |
| Record Nr. | UNINA-9910367740903321 |
Pulido Rafael
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| MDPI - Multidisciplinary Digital Publishing Institute, 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Matrix Metalloproteinases in Health and Disease
| Matrix Metalloproteinases in Health and Disease |
| Autore | Serra Raffaele |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (196 p.) |
| Soggetto topico |
Humanities
Social interaction |
| Soggetto non controllato |
hypersensitivity pneumonitis
metalloproteinases genetic association autoantibodies MMP1 MMP2 SNPs MMPs TIMPs CKD peripheral vascular disease biomarkers proteinuria eGFR PAD NGAL statins arterial aneurysms patients collagenases Crohn’s disease dental caries mouth periodontitis matrix metalloproteinase-9 dialysis on-line hemodiafiltration high-flux dialysis renal replacement therapy kidney transplantation Mac-1 CD147 leukocytes platelets adhesion integrin αMβ2 matrix metalloproteinases TIMP synthetic inhibitors RECK matrix metalloproteinase MAPKs ischemia/reperfusion eNOS iNOS inflammatory bowel disease inflammation NO MMP-9 cGMP Caco-2 matrix metalloproteinase-7 fibrosis acute kidney injury chronic kidney disease apoptosis health disease |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557409503321 |
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Serra Raffaele
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| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Strategies to Improve Antineoplastic Activity of Drugs in Cancer Progression
| Strategies to Improve Antineoplastic Activity of Drugs in Cancer Progression |
| Autore | Stefanachi Angela |
| Pubbl/distr/stampa | Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
| Descrizione fisica | 1 electronic resource (416 p.) |
| Soggetto topico |
Research & information: general
Biology, life sciences |
| Soggetto non controllato |
EGR-1
flavonoid (E)-5-((4-oxo-4H-chromen-3-yl)methyleneamino)-1-phenyl-1H-pyrazole-4-carbonitrile MDA-MB-231 MMP9 TNFα pancreatic ductal adenocarcinoma cyclodextrin inclusion complex phase solubility studies preformulation studies biphenylnicotinamide derivatives dual inhibitor EGFR VEGFR2 ligand-based pharmacophore molecular docking molecular dynamics leukemias doxorubicin inflammation drug delivery tumor targeting elastin-like polypeptide cell penetrating peptide matrix metalloproteinase doxorubicin resistance photosensitizer delivery system PAMAM dendrimer photodynamic therapy cytotoxicity phototoxicity colorectal adenocarcinoma dicarboximides chemical synthesis apoptosis kinases anticancer gene profiling SAR biomarkers colorectal cancer early detection examination liquid biopsy personalized medicine tumor treatment exosomes ctDNA CTC cytotoxic activity pyrazole derivatives MTT assay ADMET analysis single-crystal diffraction FTIR spectroscopy NMR spectroscopy thermogravimetric analysis acute myelogenous leukemia platelets microparticles γδ T cells immunotherapy tumor resistance combination therapy tumor microenvironment immune checkpoint inhibitor neuroblastoma molecular iodine cyclophosphamide xenografts metronomic therapy tamoxifen CYP2D6 MCF-7 Ishikawa cells SERM TNBC uterotrophic α-mangostin poly(amidoamine) dendrimer targeted drug delivery biotin targeting glioblastoma multiforme squamous cell carcinoma antiparasitic therapy diclofenac indomethacin oleanolic acid derivative conjugates NF-κB Nrf2 MAPKs PSN-1 cells reactive oxygen species glioblastoma brain tumor extracellular vesicles pancreatic cancer paclitaxel clathrin endocytosis sulforaphane nicotine metalloproteinase-9 gastric cancer cell invasion Arylquin 1 colon cancer tumor progression azelastine oxidative stress autophagy mitotic catastrophe chronic myeloid leukemia imatinib tyrosine kinase ketoconazole P-glycoprotein drug efflux transporter non-small-cell lung cancer cisplatin resistance aldehyde dehydrogenase isothiocyanates disulfiram epithelial to mesenchymal transition aminopeptidase N acetamidophenones Schiff bases semicarbazones thiosemicarbazones inhibition of proliferation |
| ISBN | 3-0365-5927-2 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910639990003321 |
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Stefanachi Angela
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| Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Toxicological Effects of Mycotoxins on Target Cells
| Toxicological Effects of Mycotoxins on Target Cells |
| Pubbl/distr/stampa | Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
| Descrizione fisica | 1 electronic resource (218 pages) |
| Soggetto topico | Medicine |
| Soggetto non controllato |
Destruxin A
Bombyx mori binding protein BmTudor-sn Bm12 cell Ochratoxin A (OTA) human Stem Cells mycotoxins cells cytotoxicity cell culture T-2 toxin HT-2 toxin apoptosis autophagy endophyte fungi neurotoxin lolitrems ochratoxin A beauvericin mixtures HepG2 cells genotoxicity cell cycle Fusarium Aspergillus Penicillium Alternaria emerging mycotoxin in vitro IPEC-J2 occurrence data trichothecene biosynthetic pathway acetyltransferase deacetylase deoxynivalenol 3-acetyldeoxynivalenol isotrichodermol isotrichodermin differentiated Caco-2 cells cell apoptosis transcriptome analysis hepatocyte chicken acute toxicity combined toxicity cell protection silibinin in silico prediction co-culture models mycotoxin interaction Loewe additivity combination index isobologram Chou-Talalay method MixLow IPEC-J2 cells RNA-seq inflammation MAPKs |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910557291503321 |
| Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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