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Neglected tropical diseases : drug discovery and development / / edited by David C. Swinney and Michael P. Pollastri
| Neglected tropical diseases : drug discovery and development / / edited by David C. Swinney and Michael P. Pollastri |
| Pubbl/distr/stampa | Weinheim, Germany : , : Wiley-VCH, , [2019] |
| Descrizione fisica | 1 online resource (xviii, 373 pages) : illustrations |
| Disciplina |
616.9/883
615.19 |
| Collana | Methods and principles in medicinal chemistry |
| Soggetto topico |
Tropical medicine
Drug development Tropical Medicine - methods Neglected Diseases - drug therapy Drug Discovery Drug Development |
| ISBN |
3-527-80864-7
3-527-80865-5 3-527-80862-0 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910555137003321 |
| Weinheim, Germany : , : Wiley-VCH, , [2019] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Neglected tropical diseases : drug discovery and development / / edited by David C. Swinney and Michael P. Pollastri
| Neglected tropical diseases : drug discovery and development / / edited by David C. Swinney and Michael P. Pollastri |
| Pubbl/distr/stampa | Weinheim, Germany : , : Wiley-VCH, , [2019] |
| Descrizione fisica | 1 online resource (xviii, 373 pages) : illustrations |
| Disciplina |
616.9/883
615.19 |
| Collana | Methods and principles in medicinal chemistry |
| Soggetto topico |
Tropical medicine
Drug development Tropical Medicine - methods Neglected Diseases - drug therapy Drug Discovery Drug Development |
| ISBN |
3-527-80864-7
3-527-80865-5 3-527-80862-0 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910831169403321 |
| Weinheim, Germany : , : Wiley-VCH, , [2019] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Neglected Tropical Diseases - East Asia [[electronic resource] /] / edited by Jürg Utzinger, Peiling Yap, Martin Bratschi, Peter Steinmann
| Neglected Tropical Diseases - East Asia [[electronic resource] /] / edited by Jürg Utzinger, Peiling Yap, Martin Bratschi, Peter Steinmann |
| Edizione | [1st ed. 2019.] |
| Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2019 |
| Descrizione fisica | 1 online resource (177 pages) |
| Disciplina | 616.9883 |
| Collana | Neglected Tropical Diseases |
| Soggetto topico |
Parasitology
Infectious diseases Tropical medicine Medical microbiology Public health Neglected Diseases Parasitic Diseases Tropical Medicine Infectious Diseases Medical Microbiology Public Health |
| ISBN | 3-030-12008-2 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | 1. Introduction -- 2. Foodborne trematodiases in East Asia: epidemiology and burden -- 3. Leprosy in East Asia -- 4. Dengue, an expanding neglected tropical disease -- 5. Yaws in South-East Asia: towards global eradication -- 6. Rabies in East and Southeast Asia - a mirror of the global situation -- 7. Coinfection with helminths and HIV-1 in East Asia -- 8. Links between the Epidemiology and Control of Non-Communicable Diseases and Neglected Tropical Diseases in Asia. |
| Record Nr. | UNINA-9910337938803321 |
| Cham : , : Springer International Publishing : , : Imprint : Springer, , 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Neglected Tropical Diseases - Latin America and the Caribbean [[electronic resource] /] / edited by Carlos Franco-Paredes, José Ignacio Santos-Preciado
| Neglected Tropical Diseases - Latin America and the Caribbean [[electronic resource] /] / edited by Carlos Franco-Paredes, José Ignacio Santos-Preciado |
| Edizione | [1st ed. 2015.] |
| Pubbl/distr/stampa | Vienna : , : Springer Vienna : , : Imprint : Springer, , 2015 |
| Descrizione fisica | 1 online resource (247 p.) |
| Disciplina | 616.9883 |
| Collana | Neglected Tropical Diseases |
| Soggetto topico |
Parasitology
Infectious diseases Tropical medicine Medical microbiology Epidemiology Infectious Diseases Tropical Medicine Medical Microbiology |
| ISBN | 3-7091-1422-5 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | The Neglected Tropical Diseases in Latin America and the Caribbean: Burden of Disease and Approaches for Elimination and Control -- Schistosomiasis in the Americas -- Chagas Disease -- Hookworm infection in Latin America and the Caribbean region -- Plasmodium vivax malaria in Latin America -- Leishmaniasis in the Americas -- Fascioliasis -- A roadmap followed: The path towards the elimination of onchocerciasis in Latin America -- Leprosy in the Americas: Burden of Disease and approaches for control/elimination -- Carrion’s Disease -- Dengue in Latin America: a persistent and growing public health challenge -- Cysticercosis disease burden in Latin America -- Histopathology of neglected tropical diseases. |
| Record Nr. | UNINA-9910298277803321 |
| Vienna : , : Springer Vienna : , : Imprint : Springer, , 2015 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Neglected Tropical Diseases - Middle East and North Africa [[electronic resource] /] / edited by Mary Ann McDowell, Sima Rafati
| Neglected Tropical Diseases - Middle East and North Africa [[electronic resource] /] / edited by Mary Ann McDowell, Sima Rafati |
| Edizione | [1st ed. 2014.] |
| Pubbl/distr/stampa | Vienna : , : Springer Vienna : , : Imprint : Springer, , 2014 |
| Descrizione fisica | 1 online resource (286 p.) |
| Disciplina | 616.9883 |
| Collana | Neglected Tropical Diseases |
| Soggetto topico |
Parasitology
Infectious diseases Tropical medicine Medical microbiology Public health Infectious Diseases Tropical Medicine Medical Microbiology Public Health |
| ISBN | 3-7091-1613-9 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Soil-transmitted helminths: ascariasis, trichuriasis and hookworms -- Schistosomiasis -- Fascioliasis -- Trachoma -- Cutaneous Leishmaniasis -- Visceral Leishmaniasis -- Leprosy -- Hemorrhagic Fevers -- Brucellosis -- Toxoplasmosis -- Rabies. |
| Record Nr. | UNINA-9910298350703321 |
| Vienna : , : Springer Vienna : , : Imprint : Springer, , 2014 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Neglected Tropical Diseases - Oceania [[electronic resource] /] / edited by Alex Loukas
| Neglected Tropical Diseases - Oceania [[electronic resource] /] / edited by Alex Loukas |
| Edizione | [1st ed. 2016.] |
| Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2016 |
| Descrizione fisica | 1 online resource (V, 294 p. 38 illus.) |
| Disciplina | 610 |
| Collana | Neglected Tropical Diseases |
| Soggetto topico |
Parasitology
Infectious diseases Tropical medicine Medical microbiology Public health Infectious Diseases Tropical Medicine Medical Microbiology Public Health |
| ISBN | 9783319431482 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Cholera in Oceania -- Hookworm Infection in Oceania -- Strongyloidiasis in Oceania -- Lymphatic Filariasis in Oceania -- Yaws in Oceania: new tools for the global eradication campaign -- Plasmodium vivax in Oceania -- Human Leptospirosis in Oceania -- Arboviruses of Oceania -- Dengue: emergence, determinants, and climate change -- Scabies -- Melioidosis: a neglected bacterial infection associated with high mortality. |
| Record Nr. | UNINA-9910155328803321 |
| Cham : , : Springer International Publishing : , : Imprint : Springer, , 2016 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Neglected Tropical Diseases - South Asia [[electronic resource] /] / edited by Sunit K. Singh
| Neglected Tropical Diseases - South Asia [[electronic resource] /] / edited by Sunit K. Singh |
| Edizione | [1st ed. 2017.] |
| Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2017 |
| Descrizione fisica | 1 online resource (408 pages) |
| Disciplina | 616.9883 |
| Collana | Neglected Tropical Diseases |
| Soggetto topico |
Medical microbiology
Infectious diseases Parasitology Tropical medicine Public health Tropical Medicine Neglected Diseases Medical Microbiology Infectious Diseases Public Health |
| ISBN | 3-319-68493-0 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Overview of Leishmaniasis with special emphasis on kala azar in South Asia.- Human Amebiasis: insight into the biology and immunopathogenesis -- Overview on ascariasis in humans in South-Asia.- Overview on Trichuriasis in humans -- Overview on Hookworm infection in humans.- Overview on Lymphatic Filariasis -- Leprosy -- Trachoma -- Overview of Leptospirosis -- Overview on Japanese Encephalitis in South and South-East As -- Dengue Virus -- Human rabies in South Asia -- Kyasanur Forest Disease -- Challenges for Control of Arboviral Infections in South Asia. |
| Record Nr. | UNINA-9910279578003321 |
| Cham : , : Springer International Publishing : , : Imprint : Springer, , 2017 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Neglected Tropical Diseases - Sub-Saharan Africa [[electronic resource] /] / edited by John Gyapong, Boakye Boatin
| Neglected Tropical Diseases - Sub-Saharan Africa [[electronic resource] /] / edited by John Gyapong, Boakye Boatin |
| Edizione | [1st ed. 2016.] |
| Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2016 |
| Descrizione fisica | 1 online resource (421 p.) |
| Disciplina | 616.9883 |
| Collana | Neglected Tropical Diseases |
| Soggetto topico |
Parasitology
Infectious diseases Tropical medicine Medical microbiology Public health Infectious Diseases Tropical Medicine Medical Microbiology Public Health |
| ISBN | 3-319-25471-5 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Buruli Ulcer -- Dracunculiasis (guinea-worm disease) -- Human African trypanosomiasis (Sleeping sickness) -- Leishmaniasis -- Leprosy (Hansen disease) -- Lymphatic filariasis -- Onchocerciasis (River blindness) -- Schistosomiasis (Bilharziasis) -- Soil transmitted helminthiases -- Trachoma -- Yaws (Endemic treponematoses) -- Vector Control and NTDs -- Social and economic impact of NTDs -- The role of Health Systems in the control of NTDs. |
| Record Nr. | UNINA-9910253871703321 |
| Cham : , : Springer International Publishing : , : Imprint : Springer, , 2016 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Neglected tropical diseases and phytochemicals in drug discovery / / edited by Chukwuebuka Egbuna, Muhammad Akram, Jonathan Chinenye Ifemeje
| Neglected tropical diseases and phytochemicals in drug discovery / / edited by Chukwuebuka Egbuna, Muhammad Akram, Jonathan Chinenye Ifemeje |
| Pubbl/distr/stampa | Hoboken, New Jersey : , : John Wiley & Sons, Inc., , [2022] |
| Descrizione fisica | 1 online resource (624 pages) |
| Disciplina | 616.9883 |
| Soggetto topico |
Tropical medicine
Phytochemicals - Therapeutic use |
| Soggetto genere / forma | Electronic books. |
| ISBN |
1-119-61715-4
1-119-61714-6 1-119-61711-1 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Cover -- Title Page -- Copyright Page -- Contents -- List of Contributors -- Preface -- Part I Introduction to Neglected Tropical Diseases -- Chapter 1 Epidemiology of Neglected Tropical Diseases -- List of Abbreviations -- 1.1 Introduction -- 1.2 Protozoan Infections -- 1.2.1 Human African Trypanosomiasis -- 1.2.2 Chagas Disease (American Trypanosomiasis) -- 1.2.3 Leishmaniasis -- 1.2.4 Amoebiasis -- 1.3 Helminth Infections -- 1.3.1 Soil-Transmitted Helminthiasis Infections -- 1.3.2 Schistosomiasis -- 1.3.3 Echinococcosis -- 1.3.4 Lymphatic Filariasis -- 1.3.5 Onchocerciasis ("River Blindness") -- 1.3.6 Foodborne Trematodiases -- 1.3.7 Dracunculiasis (Also Called Guinea Worm Disease) -- 1.4 Bacterial Infections -- 1.4.1 Yaws -- 1.4.2 Trachoma -- 1.4.3 Leprosy -- 1.4.4 Buruli Ulcer -- 1.5 Viral Infections -- 1.5.1 Rabies -- 1.5.2 Dengue -- 1.5.3 Chikungunya -- 1.6 Fungal and Ectoparasitic Infections -- 1.6.1 Chromoblastomycosis, Mycetoma/Eumycetoma, and Other Deep Mycoses -- 1.6.2 Scabies -- 1.6.3 Myiasis -- 1.7 Future Direction -- 1.8 Conclusion -- Acknowledgments -- References -- Chapter 2 Neglected Tropical Diseases, Phytochemicals, Protein Targets, and Mechanisms in Drug Discovery -- List of Abbreviations -- 2.1 Introduction -- 2.2 African Trypanosomiasis -- 2.2.1 Phytochemicals Against African Trypanosomiasis -- 2.3 Buruli Ulcer -- 2.3.1 Phytochemicals Against Buruli Ulcer -- 2.4 Chagas Disease -- 2.4.1 Phytochemicals Against Chagas Disease -- 2.5 Chikungunya -- 2.5.1 Phytochemicals Against Chikungunya -- 2.6 Dengue -- 2.6.1 Phytochemicals Against Dengue -- 2.7 Leishmaniasis -- 2.7.1 Phytochemicals Against Leishmaniasis -- 2.8 Leprosy -- 2.8.1 Indeterminate Leprosy -- 2.8.2 Phytochemicals Against Leprosy -- 2.9 Lymphatic Filariasis -- 2.9.1 Phytochemicals Against Lymphatic Filariasis -- 2.10 Mycetoma -- 2.10.1 Phytochemicals Against Mycetoma.
2.11 Onchocerciasis -- 2.11.1 Phytochemicals Against Onchocerciasis -- 2.12 Rabies -- 2.12.1 Phytochemicals Against Rabies -- 2.13 Scabies -- 2.13.1 Phytochemicals Against Scabies -- 2.14 Schistosomiasis -- 2.14.1 Phytochemicals Against Schistosomiasis -- 2.15 Conclusion -- References -- Chapter 3 Novel Bioactive Lead Compounds for Drug Discovery Against Neglected Tropical Diseases, Leishmaniasis, Lymphatic Filariasis, Trypanosomiasis (African Sleeping Sickness and Chagas Disease), and Schistosomiasis -- List of Abbreviations/Definitions -- 3.1 Introduction -- 3.2 Prevalence of Neglected Tropical Diseases -- 3.2.1 Leishmaniasis -- 3.2.2 Lymphatic Filariasis -- 3.2.3 Trypanosomiasis -- 3.2.3.1 African Trypanosomiasis (African Sleeping Sickness) -- 3.2.3.2 American Trypanosomiasis (Chagas Disease) -- 3.2.4 Schistosomiasis -- 3.3 Novel, Economical, and Efficacious Therapeutics from Medicinal Plants Against NTDs -- 3.3.1 Phytochemicals Effective Against Leishmania Parasite -- 3.3.2 Plants and Phytochemicals Effective Against Filarial Parasite -- 3.3.3 Plants and Phytochemicals Effective Against Trypanosomasis -- 3.3.4 Plants and Phytochemicals Effective Against Schistosomiasis -- 3.4 Future Prospects -- 3.5 Conclusion -- References -- Part II Protozoan Infections -- Chapter 4 Herbal, Nutritional, and Traditional Remedies for Giardiasis: Phytochemicals as Drug Candidates -- List of Abbreviations -- 4.1 Introduction -- 4.1.1 Epidemiology and Symptoms of Giardiasis -- 4.1.2 Life Cycle of G. duodenalis -- 4.1.3 Pathophysiology of Giardial Infection -- 4.1.4 Resistance to Allopathic Drug and Relevance of Herbal Medication -- 4.2 Plant-Based Dietary Supplements for Giardiasis Management -- 4.2.1 Oligosaccharide and Disaccharidase Supplementation -- 4.2.2 Dietary Fiber-Enriched Food -- 4.2.3 Agglutinin from Wheat -- 4.2.4 Vitamin and Mineral Supplements. 4.2.4.1 Vitamin A Supplementation -- 4.2.4.2 Compensation of Vitamin B12 -- 4.2.4.3 Zinc Status Management -- 4.2.5 Fermented Vegetables as Probiotic Source -- 4.2.6 Phenolic Compound Enriched Plant Food -- 4.3 Traditional Treatment of Giardiasis with Herbal Ethnomedicine -- 4.3.1 Hints of Antiprotozoal Medicines from Ancient Communities -- 4.3.2 Domestic Remedies and Alternative Medicine for Giardiasis -- 4.3.3 Applied Spectrum of Ethnopharmacology in Different Continents -- 4.3.3.1 Asian Medicinal Extracts -- 4.3.3.2 African Traditional Medicines -- 4.3.3.3 South American Ethnomedicine -- 4.4 Phytochemical Candidates for Advanced Giardicidal Drug Development -- 4.4.1 Terpenoids -- 4.4.2 Aromatic Ether -- 4.4.3 Alkaloids -- 4.4.4 Organo-sulfur Compounds -- 4.4.5 Lipids and Steroids -- 4.4.6 Phenolic Compounds -- 4.5 Future Prospects -- 4.5.1 Extension of Medicinal Compound Screening -- 4.5.2 Methodical Studies on Toxicology and Drug Adversity -- 4.5.3 Correlation of Herbal Drugs with Molecular Targets of Giardia -- 4.6 Summary, Prospects, and Conclusion -- References -- Chapter 5 Antiprotozoal Activity of Phytochemicals Against Entamoeba histolytica, the Causative Agent of Amoebiasis -- List of Abbreviations -- 5.1 Introduction -- 5.2 Life Cycle of Entamoeba histolytica -- 5.3 Diagnostic Techniques for Identification of E. histolytica -- 5.3.1 Intestinal Amoebiasis -- 5.3.1.1 Microscopy -- 5.3.1.2 Culture and Isoenzyme Analysis -- 5.3.1.3 Antigen Detection Test -- 5.3.1.4 Molecular-Based Test -- 5.3.1.5 Point-of-Care (POC) Test -- 5.4 Treatment of Amoebiasis -- 5.5 Alternative Treatment for Amoebiasis -- 5.6 Chemical Structure of Phytochemicals Effective Against E. histolytica -- 5.7 Possible Mechanisms of Phytochemicals as Antiamoebic -- 5.8 Future Projections -- 5.9 Conclusion -- References -- Chapter 6 Antileishmanial Potentials of Phytochemicals. 6.1 Introduction -- 6.2 Antileishmanial Activity of Propolis -- 6.2.1 Propolis from Turkey -- 6.2.2 Propolis from Brazil -- 6.2.3 Propolis from Portugal -- 6.2.4 Propolis from Cuba -- 6.2.5 Propolis from Ecuador -- 6.3 Antileishmanial Activity of Wild Mushrooms -- 6.4 Antileishmanial Activity of Medicinal Plants from Various Flora -- 6.4.1 Peruvian Flora -- 6.4.2 Ecuadorean Flora -- 6.4.3 Mexican Flora -- 6.4.4 Bolivian Flora -- 6.4.5 Iranian Flora -- 6.5 Antileishmanial Activity of Chemical Constituents -- 6.5.1 Alkaloids -- 6.5.2 Flavonoids -- 6.5.3 Terpenes -- 6.5.4 Glycoglycerolipids -- 6.5.5 Guttiferone A as a Lead Compound for Semisynthesis of Antileishmanial Molecules -- 6.6 Conclusion -- References -- Part III Helminth Infections -- Chapter 7 Prospects of Phytochemicals for the Treatment of Helminthiasis -- List of Abbreviations -- 7.1 Introduction -- 7.1.1 History -- 7.1.2 Prevalence -- 7.2 Molecular Characteristics of Soil-transmitted Helminthiasis -- 7.3 Clinical Features and Pathogenesis -- 7.4 Prevention -- 7.5 Treatment -- 7.6 Plants and Phytochemicals with Anthelmintic Activities -- 7.6.1 Modes of Action of Phytochemical Against the Soil-transmitted Helminthiasis -- 7.7 Scientific Reports of Medicinal Plants with Anthelmintic Properties -- 7.7.1 Adhatoda vasica -- 7.7.2 Allium sativum -- 7.7.3 Baliospermum montanum Muell -- 7.7.4 Butea monosperma -- 7.7.5 Calotropis procera -- 7.7.6 Carica papaya -- 7.7.7 Ficus benghalensis -- 7.7.8 Mimosa pudica -- 7.7.9 Punica granatum -- 7.7.10 Verbascum thapsus -- 7.7.11 Zingiber officinale -- 7.8 Future Prospects -- 7.9 Conclusion -- References -- Chapter 8 Efficacy of Phytochemicals of Medicinal Plants for the Treatment of Human Echinococcosis: Echinococcal Disease, Hydatidosis, or Hydatid Disease Drug Discovery -- List of Abbreviations -- 8.1 Introduction -- 8.2 Molecular Analysis. 8.3 Life Cycle of Echinococcosis -- 8.4 Previous Studies on the Positive Effects of Medicinal Plants and Phytochemicals -- 8.4.1 In vitro and in vivo Effect of Phytochemicals Against Echinococcus Infection -- 8.5 Synthetic Drugs Previously Used for Management of Echinococcosis Disease -- 8.6 Conclusion and Future Prospects -- References -- Chapter 9 Filaricidal Activity of Phytochemicals Against Lymphatic Filariasis -- List of Abbreviations -- 9.1 Introduction -- 9.2 Life Cycle of the Parasite -- 9.3 Synthetic Drugs Used for Treatment of Lymphatic Filariasis -- 9.4 Phytochemicals Used for the Treatment of Lymphatic Filariasis -- 9.4.1 Acacia auriculiformis -- 9.4.2 Aegle marmelos -- 9.4.3 Alnus nepalensis -- 9.4.4 Andrographis paniculata -- 9.4.5 Azadirachta indica -- 9.4.6 Bauhinia racemosa -- 9.4.7 Butea monosperma -- 9.4.8 Caesalpinia bonducella -- 9.4.9 Cardiospermum halicacabum -- 9.4.10 Centratherum anthelminticum -- 9.4.11 Excoecaria agallocha -- 9.4.12 Ficus racemosa -- 9.4.13 Glycyrrhiza glabra -- 9.4.14 Hibiscus sabdariffa -- 9.4.15 Lantana camara -- 9.4.16 Leucas cephalotes -- 9.4.17 Mallotus philippensis -- 9.4.18 Morinda citrifolia -- 9.4.19 Moringa oleifera -- 9.4.20 Plumbago indica -- 9.4.21 Pongamia pinnata -- 9.4.22 Psoralea corylifolia -- 9.4.23 Ricinus communis -- 9.4.24 Saxifraga stracheyion -- 9.4.25 Sphaeranthus indicus -- 9.4.26 Streblus asper -- 9.4.27 Trachyspermum ammi -- 9.4.28 Vitex negundo -- 9.4.29 Xylocarpus granatum -- 9.4.30 Zingiber officinale -- 9.5 Future Perspective -- 9.6 Conclusion -- References -- Chapter 10 Dracunculiasis (Guinea Worm Disease) and Phytochemicals in Drug Discovery -- List of Abbreviations -- 10.1 Introduction -- 10.2 Historical Insights of Dracunculiasis -- 10.3 Prevalence, Burden, and Distribution of Disease -- 10.4 Life Cycle, Pathogenesis, and Clinical Manifestations of Dracunculiasis. 10.5 Prevention and Eradication of Disease. |
| Record Nr. | UNINA-9910555163203321 |
| Hoboken, New Jersey : , : John Wiley & Sons, Inc., , [2022] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Neglected tropical diseases and phytochemicals in drug discovery / / edited by Chukwuebuka Egbuna, Muhammad Akram, Jonathan Chinenye Ifemeje
| Neglected tropical diseases and phytochemicals in drug discovery / / edited by Chukwuebuka Egbuna, Muhammad Akram, Jonathan Chinenye Ifemeje |
| Pubbl/distr/stampa | Hoboken, New Jersey : , : John Wiley & Sons, Inc., , [2022] |
| Descrizione fisica | 1 online resource (624 pages) |
| Disciplina | 616.9883 |
| Soggetto topico |
Tropical medicine
Phytochemicals - Therapeutic use |
| ISBN |
1-119-61715-4
1-119-61714-6 1-119-61711-1 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Cover -- Title Page -- Copyright Page -- Contents -- List of Contributors -- Preface -- Part I Introduction to Neglected Tropical Diseases -- Chapter 1 Epidemiology of Neglected Tropical Diseases -- List of Abbreviations -- 1.1 Introduction -- 1.2 Protozoan Infections -- 1.2.1 Human African Trypanosomiasis -- 1.2.2 Chagas Disease (American Trypanosomiasis) -- 1.2.3 Leishmaniasis -- 1.2.4 Amoebiasis -- 1.3 Helminth Infections -- 1.3.1 Soil-Transmitted Helminthiasis Infections -- 1.3.2 Schistosomiasis -- 1.3.3 Echinococcosis -- 1.3.4 Lymphatic Filariasis -- 1.3.5 Onchocerciasis ("River Blindness") -- 1.3.6 Foodborne Trematodiases -- 1.3.7 Dracunculiasis (Also Called Guinea Worm Disease) -- 1.4 Bacterial Infections -- 1.4.1 Yaws -- 1.4.2 Trachoma -- 1.4.3 Leprosy -- 1.4.4 Buruli Ulcer -- 1.5 Viral Infections -- 1.5.1 Rabies -- 1.5.2 Dengue -- 1.5.3 Chikungunya -- 1.6 Fungal and Ectoparasitic Infections -- 1.6.1 Chromoblastomycosis, Mycetoma/Eumycetoma, and Other Deep Mycoses -- 1.6.2 Scabies -- 1.6.3 Myiasis -- 1.7 Future Direction -- 1.8 Conclusion -- Acknowledgments -- References -- Chapter 2 Neglected Tropical Diseases, Phytochemicals, Protein Targets, and Mechanisms in Drug Discovery -- List of Abbreviations -- 2.1 Introduction -- 2.2 African Trypanosomiasis -- 2.2.1 Phytochemicals Against African Trypanosomiasis -- 2.3 Buruli Ulcer -- 2.3.1 Phytochemicals Against Buruli Ulcer -- 2.4 Chagas Disease -- 2.4.1 Phytochemicals Against Chagas Disease -- 2.5 Chikungunya -- 2.5.1 Phytochemicals Against Chikungunya -- 2.6 Dengue -- 2.6.1 Phytochemicals Against Dengue -- 2.7 Leishmaniasis -- 2.7.1 Phytochemicals Against Leishmaniasis -- 2.8 Leprosy -- 2.8.1 Indeterminate Leprosy -- 2.8.2 Phytochemicals Against Leprosy -- 2.9 Lymphatic Filariasis -- 2.9.1 Phytochemicals Against Lymphatic Filariasis -- 2.10 Mycetoma -- 2.10.1 Phytochemicals Against Mycetoma.
2.11 Onchocerciasis -- 2.11.1 Phytochemicals Against Onchocerciasis -- 2.12 Rabies -- 2.12.1 Phytochemicals Against Rabies -- 2.13 Scabies -- 2.13.1 Phytochemicals Against Scabies -- 2.14 Schistosomiasis -- 2.14.1 Phytochemicals Against Schistosomiasis -- 2.15 Conclusion -- References -- Chapter 3 Novel Bioactive Lead Compounds for Drug Discovery Against Neglected Tropical Diseases, Leishmaniasis, Lymphatic Filariasis, Trypanosomiasis (African Sleeping Sickness and Chagas Disease), and Schistosomiasis -- List of Abbreviations/Definitions -- 3.1 Introduction -- 3.2 Prevalence of Neglected Tropical Diseases -- 3.2.1 Leishmaniasis -- 3.2.2 Lymphatic Filariasis -- 3.2.3 Trypanosomiasis -- 3.2.3.1 African Trypanosomiasis (African Sleeping Sickness) -- 3.2.3.2 American Trypanosomiasis (Chagas Disease) -- 3.2.4 Schistosomiasis -- 3.3 Novel, Economical, and Efficacious Therapeutics from Medicinal Plants Against NTDs -- 3.3.1 Phytochemicals Effective Against Leishmania Parasite -- 3.3.2 Plants and Phytochemicals Effective Against Filarial Parasite -- 3.3.3 Plants and Phytochemicals Effective Against Trypanosomasis -- 3.3.4 Plants and Phytochemicals Effective Against Schistosomiasis -- 3.4 Future Prospects -- 3.5 Conclusion -- References -- Part II Protozoan Infections -- Chapter 4 Herbal, Nutritional, and Traditional Remedies for Giardiasis: Phytochemicals as Drug Candidates -- List of Abbreviations -- 4.1 Introduction -- 4.1.1 Epidemiology and Symptoms of Giardiasis -- 4.1.2 Life Cycle of G. duodenalis -- 4.1.3 Pathophysiology of Giardial Infection -- 4.1.4 Resistance to Allopathic Drug and Relevance of Herbal Medication -- 4.2 Plant-Based Dietary Supplements for Giardiasis Management -- 4.2.1 Oligosaccharide and Disaccharidase Supplementation -- 4.2.2 Dietary Fiber-Enriched Food -- 4.2.3 Agglutinin from Wheat -- 4.2.4 Vitamin and Mineral Supplements. 4.2.4.1 Vitamin A Supplementation -- 4.2.4.2 Compensation of Vitamin B12 -- 4.2.4.3 Zinc Status Management -- 4.2.5 Fermented Vegetables as Probiotic Source -- 4.2.6 Phenolic Compound Enriched Plant Food -- 4.3 Traditional Treatment of Giardiasis with Herbal Ethnomedicine -- 4.3.1 Hints of Antiprotozoal Medicines from Ancient Communities -- 4.3.2 Domestic Remedies and Alternative Medicine for Giardiasis -- 4.3.3 Applied Spectrum of Ethnopharmacology in Different Continents -- 4.3.3.1 Asian Medicinal Extracts -- 4.3.3.2 African Traditional Medicines -- 4.3.3.3 South American Ethnomedicine -- 4.4 Phytochemical Candidates for Advanced Giardicidal Drug Development -- 4.4.1 Terpenoids -- 4.4.2 Aromatic Ether -- 4.4.3 Alkaloids -- 4.4.4 Organo-sulfur Compounds -- 4.4.5 Lipids and Steroids -- 4.4.6 Phenolic Compounds -- 4.5 Future Prospects -- 4.5.1 Extension of Medicinal Compound Screening -- 4.5.2 Methodical Studies on Toxicology and Drug Adversity -- 4.5.3 Correlation of Herbal Drugs with Molecular Targets of Giardia -- 4.6 Summary, Prospects, and Conclusion -- References -- Chapter 5 Antiprotozoal Activity of Phytochemicals Against Entamoeba histolytica, the Causative Agent of Amoebiasis -- List of Abbreviations -- 5.1 Introduction -- 5.2 Life Cycle of Entamoeba histolytica -- 5.3 Diagnostic Techniques for Identification of E. histolytica -- 5.3.1 Intestinal Amoebiasis -- 5.3.1.1 Microscopy -- 5.3.1.2 Culture and Isoenzyme Analysis -- 5.3.1.3 Antigen Detection Test -- 5.3.1.4 Molecular-Based Test -- 5.3.1.5 Point-of-Care (POC) Test -- 5.4 Treatment of Amoebiasis -- 5.5 Alternative Treatment for Amoebiasis -- 5.6 Chemical Structure of Phytochemicals Effective Against E. histolytica -- 5.7 Possible Mechanisms of Phytochemicals as Antiamoebic -- 5.8 Future Projections -- 5.9 Conclusion -- References -- Chapter 6 Antileishmanial Potentials of Phytochemicals. 6.1 Introduction -- 6.2 Antileishmanial Activity of Propolis -- 6.2.1 Propolis from Turkey -- 6.2.2 Propolis from Brazil -- 6.2.3 Propolis from Portugal -- 6.2.4 Propolis from Cuba -- 6.2.5 Propolis from Ecuador -- 6.3 Antileishmanial Activity of Wild Mushrooms -- 6.4 Antileishmanial Activity of Medicinal Plants from Various Flora -- 6.4.1 Peruvian Flora -- 6.4.2 Ecuadorean Flora -- 6.4.3 Mexican Flora -- 6.4.4 Bolivian Flora -- 6.4.5 Iranian Flora -- 6.5 Antileishmanial Activity of Chemical Constituents -- 6.5.1 Alkaloids -- 6.5.2 Flavonoids -- 6.5.3 Terpenes -- 6.5.4 Glycoglycerolipids -- 6.5.5 Guttiferone A as a Lead Compound for Semisynthesis of Antileishmanial Molecules -- 6.6 Conclusion -- References -- Part III Helminth Infections -- Chapter 7 Prospects of Phytochemicals for the Treatment of Helminthiasis -- List of Abbreviations -- 7.1 Introduction -- 7.1.1 History -- 7.1.2 Prevalence -- 7.2 Molecular Characteristics of Soil-transmitted Helminthiasis -- 7.3 Clinical Features and Pathogenesis -- 7.4 Prevention -- 7.5 Treatment -- 7.6 Plants and Phytochemicals with Anthelmintic Activities -- 7.6.1 Modes of Action of Phytochemical Against the Soil-transmitted Helminthiasis -- 7.7 Scientific Reports of Medicinal Plants with Anthelmintic Properties -- 7.7.1 Adhatoda vasica -- 7.7.2 Allium sativum -- 7.7.3 Baliospermum montanum Muell -- 7.7.4 Butea monosperma -- 7.7.5 Calotropis procera -- 7.7.6 Carica papaya -- 7.7.7 Ficus benghalensis -- 7.7.8 Mimosa pudica -- 7.7.9 Punica granatum -- 7.7.10 Verbascum thapsus -- 7.7.11 Zingiber officinale -- 7.8 Future Prospects -- 7.9 Conclusion -- References -- Chapter 8 Efficacy of Phytochemicals of Medicinal Plants for the Treatment of Human Echinococcosis: Echinococcal Disease, Hydatidosis, or Hydatid Disease Drug Discovery -- List of Abbreviations -- 8.1 Introduction -- 8.2 Molecular Analysis. 8.3 Life Cycle of Echinococcosis -- 8.4 Previous Studies on the Positive Effects of Medicinal Plants and Phytochemicals -- 8.4.1 In vitro and in vivo Effect of Phytochemicals Against Echinococcus Infection -- 8.5 Synthetic Drugs Previously Used for Management of Echinococcosis Disease -- 8.6 Conclusion and Future Prospects -- References -- Chapter 9 Filaricidal Activity of Phytochemicals Against Lymphatic Filariasis -- List of Abbreviations -- 9.1 Introduction -- 9.2 Life Cycle of the Parasite -- 9.3 Synthetic Drugs Used for Treatment of Lymphatic Filariasis -- 9.4 Phytochemicals Used for the Treatment of Lymphatic Filariasis -- 9.4.1 Acacia auriculiformis -- 9.4.2 Aegle marmelos -- 9.4.3 Alnus nepalensis -- 9.4.4 Andrographis paniculata -- 9.4.5 Azadirachta indica -- 9.4.6 Bauhinia racemosa -- 9.4.7 Butea monosperma -- 9.4.8 Caesalpinia bonducella -- 9.4.9 Cardiospermum halicacabum -- 9.4.10 Centratherum anthelminticum -- 9.4.11 Excoecaria agallocha -- 9.4.12 Ficus racemosa -- 9.4.13 Glycyrrhiza glabra -- 9.4.14 Hibiscus sabdariffa -- 9.4.15 Lantana camara -- 9.4.16 Leucas cephalotes -- 9.4.17 Mallotus philippensis -- 9.4.18 Morinda citrifolia -- 9.4.19 Moringa oleifera -- 9.4.20 Plumbago indica -- 9.4.21 Pongamia pinnata -- 9.4.22 Psoralea corylifolia -- 9.4.23 Ricinus communis -- 9.4.24 Saxifraga stracheyion -- 9.4.25 Sphaeranthus indicus -- 9.4.26 Streblus asper -- 9.4.27 Trachyspermum ammi -- 9.4.28 Vitex negundo -- 9.4.29 Xylocarpus granatum -- 9.4.30 Zingiber officinale -- 9.5 Future Perspective -- 9.6 Conclusion -- References -- Chapter 10 Dracunculiasis (Guinea Worm Disease) and Phytochemicals in Drug Discovery -- List of Abbreviations -- 10.1 Introduction -- 10.2 Historical Insights of Dracunculiasis -- 10.3 Prevalence, Burden, and Distribution of Disease -- 10.4 Life Cycle, Pathogenesis, and Clinical Manifestations of Dracunculiasis. 10.5 Prevention and Eradication of Disease. |
| Record Nr. | UNINA-9910830428403321 |
| Hoboken, New Jersey : , : John Wiley & Sons, Inc., , [2022] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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