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Touch, heat, and pain [[electronic resource] ] : [proceedings] Ciba Foundation Symposium / / edited by A.V.S. de Reuck and Julie Knight
| Touch, heat, and pain [[electronic resource] ] : [proceedings] Ciba Foundation Symposium / / edited by A.V.S. de Reuck and Julie Knight |
| Pubbl/distr/stampa | London, : Churchill Ltd., 1966 |
| Descrizione fisica | 1 online resource (433 p.) |
| Disciplina |
591.1/8
591.18 |
| Altri autori (Persone) |
De ReuckAnthony V. S
KnightJulie |
| Collana | Novartis Foundation Symposia |
| Soggetto topico |
Sense organs
Senses and sensation |
| Soggetto genere / forma | Electronic books. |
| ISBN |
0-470-71533-2
0-470-71502-2 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
TOUCH, HEAT AND PAIN; Preface; Contents; Chairman's introduction; Section I. Discrimination of quantitative differences in stimuli in man; Transfer functions of the skin and muscle senses; Discussion; Tissue temperature and thermal pain; Discussion; Measurement of responses to chemically induced pain; Discussion; General discussion of Section I; Linearity of transmission along the perceptual pathway; Section II. Structure of receptor organs; Unit design and array patterns in receptor organs; Discussion; Fine structure of the receptor organs and its probable functional significance; Discussion
General discussion of Section IIChemical or physical nature of transduction; Induction of receptor properties; Specificity of first-order fibres; Section III. Basic mechanisms: biophysics of supporting tissues and receptors; The relationship of skin displacement to receptor activation; Discussion; Nerve membrane properties and thermal stimulation; Discussion; Input and output ends ofa transducer process; Discussion; Initiation of impulses by mechanorensory nerve terminals; Discussion; General discussion of Section III; Function of lamellar cells of encapsulated organs Cell membrance junctionsTerminal concentrations of mitochondria; Section IV. Relation of single receptor activity to parameters of stimuli; Cutaneous receptors with a high sensitivity tomechanical displacement; Discussion; Excitation of the dentinal receptor in the tooth of the cat; Discussion; Classes of receptor units predominantly related to thermal stimuli; Discussion; General discussion of Section IV; Central integration over neural space; Sensitivity of temperature detection in man; Existence of sympathetic thermosensitive fibres Section V. Relation of activity of populations of receptors to parameters of stimuliThe representation of information about rapid changes in a posulation of receptor units signaning mechanical events; Discussion; The neural transformation of mechanical stimuli delivered to the monkey's hand; Discussion; General discussion of Section V; Factors affecting sensitivity of cutaneous mechanoreceptors; Minimal cortical input; Concluding Discussion; The neurohistology of touch, heat and pain; Pain and pain receptors; Lines for future research; Chairman's closing remarks; Author index; Subject index |
| Record Nr. | UNINA-9910144666303321 |
| London, : Churchill Ltd., 1966 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Touch, heat, and pain [[electronic resource] ] : [proceedings] Ciba Foundation Symposium / / edited by A.V.S. de Reuck and Julie Knight
| Touch, heat, and pain [[electronic resource] ] : [proceedings] Ciba Foundation Symposium / / edited by A.V.S. de Reuck and Julie Knight |
| Pubbl/distr/stampa | London, : Churchill Ltd., 1966 |
| Descrizione fisica | 1 online resource (433 p.) |
| Disciplina |
591.1/8
591.18 |
| Altri autori (Persone) |
De ReuckAnthony V. S
KnightJulie |
| Collana | Novartis Foundation Symposia |
| Soggetto topico |
Sense organs
Senses and sensation |
| ISBN |
0-470-71533-2
0-470-71502-2 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
TOUCH, HEAT AND PAIN; Preface; Contents; Chairman's introduction; Section I. Discrimination of quantitative differences in stimuli in man; Transfer functions of the skin and muscle senses; Discussion; Tissue temperature and thermal pain; Discussion; Measurement of responses to chemically induced pain; Discussion; General discussion of Section I; Linearity of transmission along the perceptual pathway; Section II. Structure of receptor organs; Unit design and array patterns in receptor organs; Discussion; Fine structure of the receptor organs and its probable functional significance; Discussion
General discussion of Section IIChemical or physical nature of transduction; Induction of receptor properties; Specificity of first-order fibres; Section III. Basic mechanisms: biophysics of supporting tissues and receptors; The relationship of skin displacement to receptor activation; Discussion; Nerve membrane properties and thermal stimulation; Discussion; Input and output ends ofa transducer process; Discussion; Initiation of impulses by mechanorensory nerve terminals; Discussion; General discussion of Section III; Function of lamellar cells of encapsulated organs Cell membrance junctionsTerminal concentrations of mitochondria; Section IV. Relation of single receptor activity to parameters of stimuli; Cutaneous receptors with a high sensitivity tomechanical displacement; Discussion; Excitation of the dentinal receptor in the tooth of the cat; Discussion; Classes of receptor units predominantly related to thermal stimuli; Discussion; General discussion of Section IV; Central integration over neural space; Sensitivity of temperature detection in man; Existence of sympathetic thermosensitive fibres Section V. Relation of activity of populations of receptors to parameters of stimuliThe representation of information about rapid changes in a posulation of receptor units signaning mechanical events; Discussion; The neural transformation of mechanical stimuli delivered to the monkey's hand; Discussion; General discussion of Section V; Factors affecting sensitivity of cutaneous mechanoreceptors; Minimal cortical input; Concluding Discussion; The neurohistology of touch, heat and pain; Pain and pain receptors; Lines for future research; Chairman's closing remarks; Author index; Subject index |
| Record Nr. | UNINA-9910643784103321 |
| London, : Churchill Ltd., 1966 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Touch, heat, and pain [[electronic resource] ] : [proceedings] Ciba Foundation Symposium / / edited by A.V.S. de Reuck and Julie Knight
| Touch, heat, and pain [[electronic resource] ] : [proceedings] Ciba Foundation Symposium / / edited by A.V.S. de Reuck and Julie Knight |
| Pubbl/distr/stampa | London, : Churchill Ltd., 1966 |
| Descrizione fisica | 1 online resource (433 p.) |
| Disciplina |
591.1/8
591.18 |
| Altri autori (Persone) |
De ReuckAnthony V. S
KnightJulie |
| Collana | Novartis Foundation Symposia |
| Soggetto topico |
Sense organs
Senses and sensation |
| ISBN |
0-470-71533-2
0-470-71502-2 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
TOUCH, HEAT AND PAIN; Preface; Contents; Chairman's introduction; Section I. Discrimination of quantitative differences in stimuli in man; Transfer functions of the skin and muscle senses; Discussion; Tissue temperature and thermal pain; Discussion; Measurement of responses to chemically induced pain; Discussion; General discussion of Section I; Linearity of transmission along the perceptual pathway; Section II. Structure of receptor organs; Unit design and array patterns in receptor organs; Discussion; Fine structure of the receptor organs and its probable functional significance; Discussion
General discussion of Section IIChemical or physical nature of transduction; Induction of receptor properties; Specificity of first-order fibres; Section III. Basic mechanisms: biophysics of supporting tissues and receptors; The relationship of skin displacement to receptor activation; Discussion; Nerve membrane properties and thermal stimulation; Discussion; Input and output ends ofa transducer process; Discussion; Initiation of impulses by mechanorensory nerve terminals; Discussion; General discussion of Section III; Function of lamellar cells of encapsulated organs Cell membrance junctionsTerminal concentrations of mitochondria; Section IV. Relation of single receptor activity to parameters of stimuli; Cutaneous receptors with a high sensitivity tomechanical displacement; Discussion; Excitation of the dentinal receptor in the tooth of the cat; Discussion; Classes of receptor units predominantly related to thermal stimuli; Discussion; General discussion of Section IV; Central integration over neural space; Sensitivity of temperature detection in man; Existence of sympathetic thermosensitive fibres Section V. Relation of activity of populations of receptors to parameters of stimuliThe representation of information about rapid changes in a posulation of receptor units signaning mechanical events; Discussion; The neural transformation of mechanical stimuli delivered to the monkey's hand; Discussion; General discussion of Section V; Factors affecting sensitivity of cutaneous mechanoreceptors; Minimal cortical input; Concluding Discussion; The neurohistology of touch, heat and pain; Pain and pain receptors; Lines for future research; Chairman's closing remarks; Author index; Subject index |
| Record Nr. | UNISA-996202095603316 |
| London, : Churchill Ltd., 1966 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. di Salerno | ||
| ||
Touch, heat, and pain [[electronic resource] ] : [proceedings] Ciba Foundation Symposium / / edited by A.V.S. de Reuck and Julie Knight
| Touch, heat, and pain [[electronic resource] ] : [proceedings] Ciba Foundation Symposium / / edited by A.V.S. de Reuck and Julie Knight |
| Pubbl/distr/stampa | London, : Churchill Ltd., 1966 |
| Descrizione fisica | 1 online resource (433 p.) |
| Disciplina |
591.1/8
591.18 |
| Altri autori (Persone) |
De ReuckAnthony V. S
KnightJulie |
| Collana | Novartis Foundation Symposia |
| Soggetto topico |
Sense organs
Senses and sensation |
| ISBN |
0-470-71533-2
0-470-71502-2 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
TOUCH, HEAT AND PAIN; Preface; Contents; Chairman's introduction; Section I. Discrimination of quantitative differences in stimuli in man; Transfer functions of the skin and muscle senses; Discussion; Tissue temperature and thermal pain; Discussion; Measurement of responses to chemically induced pain; Discussion; General discussion of Section I; Linearity of transmission along the perceptual pathway; Section II. Structure of receptor organs; Unit design and array patterns in receptor organs; Discussion; Fine structure of the receptor organs and its probable functional significance; Discussion
General discussion of Section IIChemical or physical nature of transduction; Induction of receptor properties; Specificity of first-order fibres; Section III. Basic mechanisms: biophysics of supporting tissues and receptors; The relationship of skin displacement to receptor activation; Discussion; Nerve membrane properties and thermal stimulation; Discussion; Input and output ends ofa transducer process; Discussion; Initiation of impulses by mechanorensory nerve terminals; Discussion; General discussion of Section III; Function of lamellar cells of encapsulated organs Cell membrance junctionsTerminal concentrations of mitochondria; Section IV. Relation of single receptor activity to parameters of stimuli; Cutaneous receptors with a high sensitivity tomechanical displacement; Discussion; Excitation of the dentinal receptor in the tooth of the cat; Discussion; Classes of receptor units predominantly related to thermal stimuli; Discussion; General discussion of Section IV; Central integration over neural space; Sensitivity of temperature detection in man; Existence of sympathetic thermosensitive fibres Section V. Relation of activity of populations of receptors to parameters of stimuliThe representation of information about rapid changes in a posulation of receptor units signaning mechanical events; Discussion; The neural transformation of mechanical stimuli delivered to the monkey's hand; Discussion; General discussion of Section V; Factors affecting sensitivity of cutaneous mechanoreceptors; Minimal cortical input; Concluding Discussion; The neurohistology of touch, heat and pain; Pain and pain receptors; Lines for future research; Chairman's closing remarks; Author index; Subject index |
| Record Nr. | UNINA-9910830592303321 |
| London, : Churchill Ltd., 1966 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Touch, heat, and pain : [proceedings] Ciba Foundation Symposium / / edited by A.V.S. de Reuck and Julie Knight
| Touch, heat, and pain : [proceedings] Ciba Foundation Symposium / / edited by A.V.S. de Reuck and Julie Knight |
| Pubbl/distr/stampa | London, : Churchill Ltd., 1966 |
| Descrizione fisica | 1 online resource (433 p.) |
| Disciplina | 591.1/8 |
| Altri autori (Persone) |
De ReuckAnthony V. S
KnightJulie |
| Collana | Novartis Foundation Symposia |
| Soggetto topico |
Sense organs
Senses and sensation |
| ISBN |
0-470-71533-2
0-470-71502-2 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
TOUCH, HEAT AND PAIN; Preface; Contents; Chairman's introduction; Section I. Discrimination of quantitative differences in stimuli in man; Transfer functions of the skin and muscle senses; Discussion; Tissue temperature and thermal pain; Discussion; Measurement of responses to chemically induced pain; Discussion; General discussion of Section I; Linearity of transmission along the perceptual pathway; Section II. Structure of receptor organs; Unit design and array patterns in receptor organs; Discussion; Fine structure of the receptor organs and its probable functional significance; Discussion
General discussion of Section IIChemical or physical nature of transduction; Induction of receptor properties; Specificity of first-order fibres; Section III. Basic mechanisms: biophysics of supporting tissues and receptors; The relationship of skin displacement to receptor activation; Discussion; Nerve membrane properties and thermal stimulation; Discussion; Input and output ends ofa transducer process; Discussion; Initiation of impulses by mechanorensory nerve terminals; Discussion; General discussion of Section III; Function of lamellar cells of encapsulated organs Cell membrance junctionsTerminal concentrations of mitochondria; Section IV. Relation of single receptor activity to parameters of stimuli; Cutaneous receptors with a high sensitivity tomechanical displacement; Discussion; Excitation of the dentinal receptor in the tooth of the cat; Discussion; Classes of receptor units predominantly related to thermal stimuli; Discussion; General discussion of Section IV; Central integration over neural space; Sensitivity of temperature detection in man; Existence of sympathetic thermosensitive fibres Section V. Relation of activity of populations of receptors to parameters of stimuliThe representation of information about rapid changes in a posulation of receptor units signaning mechanical events; Discussion; The neural transformation of mechanical stimuli delivered to the monkey's hand; Discussion; General discussion of Section V; Factors affecting sensitivity of cutaneous mechanoreceptors; Minimal cortical input; Concluding Discussion; The neurohistology of touch, heat and pain; Pain and pain receptors; Lines for future research; Chairman's closing remarks; Author index; Subject index |
| Record Nr. | UNINA-9910877213003321 |
| London, : Churchill Ltd., 1966 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Transduction channels in sensory cells [[electronic resource] /] / edited by Stephan Frings and Jonathan Bradley
| Transduction channels in sensory cells [[electronic resource] /] / edited by Stephan Frings and Jonathan Bradley |
| Pubbl/distr/stampa | Weinheim, : Wiley-VCH, c2004 |
| Descrizione fisica | 1 online resource (324 p.) |
| Disciplina | 571.74 |
| Altri autori (Persone) |
FringsStephan
BradleyJonathan <1961-> |
| Soggetto topico |
Cellular signal transduction
Senses and sensation Molecular biology |
| Soggetto genere / forma | Electronic books. |
| ISBN |
1-280-52012-4
9786610520121 3-527-60391-3 3-527-60497-9 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Transduction Channels in Sensory Cells; Table of Contents; Preface; List of Contributers; 1 The Molecular Basis of Touch Sensation as Modeled in Caenorhabditis elegans; Abstract; 1.1 Introduction; 1.2 Features of the C. elegans Model System; 1.3 Mechanosensation Is a Major Mechanism by Which C. elegans Senses Its Environment; 1.4 Gentle Body Touch; 1.4.1 The Touch Receptor Neurons; 1.4.2 Ultrastructural Features of the Touch Receptor Neurons; 1.4.2.1 Touch Cell-specific Microtubules; 1.4.2.2 The Extracellular Mantle; 1.4.3 Genetic and Molecular Analysis of Body Touch
1.4.3.1 mec-4 and mec-10 Ion Channel Subunits Form Na(+) Channels1.4.3.2 MEC-4 at the Molecular Level; 1.4.4 The Candidate Mechanotransducing Channel is a Heteromultimeric Complex; 1.4.4.1 MEC-4 and MEC-10 Form a Functional Ion Channel; 1.4.4.2 MEC-2 Is a Stomatin-like Protein That May Help Tether the MEC-4/MEC-10 Channel to the Membrane Bilayer and/or the Cytoskeleton; 1.4.4.3 MEC-6 Is a Transmembrane Paraoxonase-like Protein That Controls MEC Channel Activity; 1.4.5 Intracellular Proteins Needed for Touch Transduction; 1.4.6 Extracellular Proteins Needed for Touch Transduction 1.4.6.1 MEC-11.4.6.2 MEC-5; 1.4.6.3 MEC-9; 1.4.7 The MEC Channel Functions Specifically in Neuronal Responses to Gentle Touch; 1.4.7.1 Test of a Key Hypothesis; 1.4.7.2 Additional Insights Revealed by Imaging In Vivo Ca(2+) Changes in Responding Touch Neurons; 1.4.8 Summary: A Molecular Model for Gentle-touch Sensation; 1.4.8.1 How Touch Is Sensed to Elicit a Specific Behavioral Response; 1.4.8.2 Notes on the Working Model; 1.5 The C. elegans Degenerin Family: A Global Role of Degenerin Channels in Mechanotransduction?; 1.5.1 unc-105; 1.5.2 unc-8 and del-1 1.5.2.1 A Stomatin Partner for the UNC-8 Channel Suggests a Common Composition of Degenerin Channels1.5.2.2 Trp Channels May Also Contribute to Mechanosensory Functions in C. elegans; 1.5.2.3 Fly and Mouse Neuronal DEG/ENaCs Influence Mechanotransduction, Supporting Conserved Roles for This Family of Proteins; 1.6 Concluding Remarks; Acknowledgments; References; 2 Transduction Channels in Hair Cells; 2.1 Introduction; 2.2 Gating Mechanism: Channel Kinetics; 2.2.1 Tip Links and Gating Springs; 2.2.2 Gating Compliance; 2.2.3 Three-state Channel Schemes; 2.3 Ionic Selectivity 2.3.1 Blocking Compounds2.4 MET Channel Adaptation; 2.4.1 Ca(2+) Regulation of Adaptation; 2.4.2 The Function of Adaptation; 2.5 Single-channel Conductance; 2.5.1 Number of MET Channels Per Stereocilium; 2.6 The MET Channel as a Member of the TRP Family; 2.6.1 Properties of TRPV Channels; 2.7 Conclusions; Acknowledgments; References; 3 Acid-sensing Ion Channels; 3.1 Introduction; 3.2 ASICs and the DEG/ENaC Superfamily; 3.3 Amino Acid Structure; 3.4 Assembly Into Channels; 3.5 Pharmacology; 3.6 Gating; 3.7 Proposed Sensory Functions; 3.7.1 Pain/Nociception; 3.7.2 Mechanosensation; 3.7.3 Taste 3.8 CNS ASICs |
| Record Nr. | UNINA-9910144557703321 |
| Weinheim, : Wiley-VCH, c2004 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Transduction channels in sensory cells [[electronic resource] /] / edited by Stephan Frings and Jonathan Bradley
| Transduction channels in sensory cells [[electronic resource] /] / edited by Stephan Frings and Jonathan Bradley |
| Pubbl/distr/stampa | Weinheim, : Wiley-VCH, c2004 |
| Descrizione fisica | 1 online resource (324 p.) |
| Disciplina | 571.74 |
| Altri autori (Persone) |
FringsStephan
BradleyJonathan <1961-> |
| Soggetto topico |
Cellular signal transduction
Senses and sensation Molecular biology |
| ISBN |
1-280-52012-4
9786610520121 3-527-60391-3 3-527-60497-9 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Transduction Channels in Sensory Cells; Table of Contents; Preface; List of Contributers; 1 The Molecular Basis of Touch Sensation as Modeled in Caenorhabditis elegans; Abstract; 1.1 Introduction; 1.2 Features of the C. elegans Model System; 1.3 Mechanosensation Is a Major Mechanism by Which C. elegans Senses Its Environment; 1.4 Gentle Body Touch; 1.4.1 The Touch Receptor Neurons; 1.4.2 Ultrastructural Features of the Touch Receptor Neurons; 1.4.2.1 Touch Cell-specific Microtubules; 1.4.2.2 The Extracellular Mantle; 1.4.3 Genetic and Molecular Analysis of Body Touch
1.4.3.1 mec-4 and mec-10 Ion Channel Subunits Form Na(+) Channels1.4.3.2 MEC-4 at the Molecular Level; 1.4.4 The Candidate Mechanotransducing Channel is a Heteromultimeric Complex; 1.4.4.1 MEC-4 and MEC-10 Form a Functional Ion Channel; 1.4.4.2 MEC-2 Is a Stomatin-like Protein That May Help Tether the MEC-4/MEC-10 Channel to the Membrane Bilayer and/or the Cytoskeleton; 1.4.4.3 MEC-6 Is a Transmembrane Paraoxonase-like Protein That Controls MEC Channel Activity; 1.4.5 Intracellular Proteins Needed for Touch Transduction; 1.4.6 Extracellular Proteins Needed for Touch Transduction 1.4.6.1 MEC-11.4.6.2 MEC-5; 1.4.6.3 MEC-9; 1.4.7 The MEC Channel Functions Specifically in Neuronal Responses to Gentle Touch; 1.4.7.1 Test of a Key Hypothesis; 1.4.7.2 Additional Insights Revealed by Imaging In Vivo Ca(2+) Changes in Responding Touch Neurons; 1.4.8 Summary: A Molecular Model for Gentle-touch Sensation; 1.4.8.1 How Touch Is Sensed to Elicit a Specific Behavioral Response; 1.4.8.2 Notes on the Working Model; 1.5 The C. elegans Degenerin Family: A Global Role of Degenerin Channels in Mechanotransduction?; 1.5.1 unc-105; 1.5.2 unc-8 and del-1 1.5.2.1 A Stomatin Partner for the UNC-8 Channel Suggests a Common Composition of Degenerin Channels1.5.2.2 Trp Channels May Also Contribute to Mechanosensory Functions in C. elegans; 1.5.2.3 Fly and Mouse Neuronal DEG/ENaCs Influence Mechanotransduction, Supporting Conserved Roles for This Family of Proteins; 1.6 Concluding Remarks; Acknowledgments; References; 2 Transduction Channels in Hair Cells; 2.1 Introduction; 2.2 Gating Mechanism: Channel Kinetics; 2.2.1 Tip Links and Gating Springs; 2.2.2 Gating Compliance; 2.2.3 Three-state Channel Schemes; 2.3 Ionic Selectivity 2.3.1 Blocking Compounds2.4 MET Channel Adaptation; 2.4.1 Ca(2+) Regulation of Adaptation; 2.4.2 The Function of Adaptation; 2.5 Single-channel Conductance; 2.5.1 Number of MET Channels Per Stereocilium; 2.6 The MET Channel as a Member of the TRP Family; 2.6.1 Properties of TRPV Channels; 2.7 Conclusions; Acknowledgments; References; 3 Acid-sensing Ion Channels; 3.1 Introduction; 3.2 ASICs and the DEG/ENaC Superfamily; 3.3 Amino Acid Structure; 3.4 Assembly Into Channels; 3.5 Pharmacology; 3.6 Gating; 3.7 Proposed Sensory Functions; 3.7.1 Pain/Nociception; 3.7.2 Mechanosensation; 3.7.3 Taste 3.8 CNS ASICs |
| Record Nr. | UNINA-9910831180603321 |
| Weinheim, : Wiley-VCH, c2004 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Transduction channels in sensory cells / / edited by Stephan Frings and Jonathan Bradley
| Transduction channels in sensory cells / / edited by Stephan Frings and Jonathan Bradley |
| Pubbl/distr/stampa | Weinheim, : Wiley-VCH, c2004 |
| Descrizione fisica | 1 online resource (324 p.) |
| Disciplina | 571.74 |
| Altri autori (Persone) |
FringsStephan
BradleyJonathan <1961-> |
| Soggetto topico |
Cellular signal transduction
Senses and sensation Molecular biology |
| ISBN |
1-280-52012-4
9786610520121 3-527-60391-3 3-527-60497-9 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Transduction Channels in Sensory Cells; Table of Contents; Preface; List of Contributers; 1 The Molecular Basis of Touch Sensation as Modeled in Caenorhabditis elegans; Abstract; 1.1 Introduction; 1.2 Features of the C. elegans Model System; 1.3 Mechanosensation Is a Major Mechanism by Which C. elegans Senses Its Environment; 1.4 Gentle Body Touch; 1.4.1 The Touch Receptor Neurons; 1.4.2 Ultrastructural Features of the Touch Receptor Neurons; 1.4.2.1 Touch Cell-specific Microtubules; 1.4.2.2 The Extracellular Mantle; 1.4.3 Genetic and Molecular Analysis of Body Touch
1.4.3.1 mec-4 and mec-10 Ion Channel Subunits Form Na(+) Channels1.4.3.2 MEC-4 at the Molecular Level; 1.4.4 The Candidate Mechanotransducing Channel is a Heteromultimeric Complex; 1.4.4.1 MEC-4 and MEC-10 Form a Functional Ion Channel; 1.4.4.2 MEC-2 Is a Stomatin-like Protein That May Help Tether the MEC-4/MEC-10 Channel to the Membrane Bilayer and/or the Cytoskeleton; 1.4.4.3 MEC-6 Is a Transmembrane Paraoxonase-like Protein That Controls MEC Channel Activity; 1.4.5 Intracellular Proteins Needed for Touch Transduction; 1.4.6 Extracellular Proteins Needed for Touch Transduction 1.4.6.1 MEC-11.4.6.2 MEC-5; 1.4.6.3 MEC-9; 1.4.7 The MEC Channel Functions Specifically in Neuronal Responses to Gentle Touch; 1.4.7.1 Test of a Key Hypothesis; 1.4.7.2 Additional Insights Revealed by Imaging In Vivo Ca(2+) Changes in Responding Touch Neurons; 1.4.8 Summary: A Molecular Model for Gentle-touch Sensation; 1.4.8.1 How Touch Is Sensed to Elicit a Specific Behavioral Response; 1.4.8.2 Notes on the Working Model; 1.5 The C. elegans Degenerin Family: A Global Role of Degenerin Channels in Mechanotransduction?; 1.5.1 unc-105; 1.5.2 unc-8 and del-1 1.5.2.1 A Stomatin Partner for the UNC-8 Channel Suggests a Common Composition of Degenerin Channels1.5.2.2 Trp Channels May Also Contribute to Mechanosensory Functions in C. elegans; 1.5.2.3 Fly and Mouse Neuronal DEG/ENaCs Influence Mechanotransduction, Supporting Conserved Roles for This Family of Proteins; 1.6 Concluding Remarks; Acknowledgments; References; 2 Transduction Channels in Hair Cells; 2.1 Introduction; 2.2 Gating Mechanism: Channel Kinetics; 2.2.1 Tip Links and Gating Springs; 2.2.2 Gating Compliance; 2.2.3 Three-state Channel Schemes; 2.3 Ionic Selectivity 2.3.1 Blocking Compounds2.4 MET Channel Adaptation; 2.4.1 Ca(2+) Regulation of Adaptation; 2.4.2 The Function of Adaptation; 2.5 Single-channel Conductance; 2.5.1 Number of MET Channels Per Stereocilium; 2.6 The MET Channel as a Member of the TRP Family; 2.6.1 Properties of TRPV Channels; 2.7 Conclusions; Acknowledgments; References; 3 Acid-sensing Ion Channels; 3.1 Introduction; 3.2 ASICs and the DEG/ENaC Superfamily; 3.3 Amino Acid Structure; 3.4 Assembly Into Channels; 3.5 Pharmacology; 3.6 Gating; 3.7 Proposed Sensory Functions; 3.7.1 Pain/Nociception; 3.7.2 Mechanosensation; 3.7.3 Taste 3.8 CNS ASICs |
| Record Nr. | UNINA-9910877982903321 |
| Weinheim, : Wiley-VCH, c2004 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Visceral sensory neuroscience [[electronic resource] ] : interoception / / Oliver G. Cameron
| Visceral sensory neuroscience [[electronic resource] ] : interoception / / Oliver G. Cameron |
| Autore | Cameron Oliver G |
| Pubbl/distr/stampa | Oxford ; ; New York, : Oxford University Press, 2002 |
| Descrizione fisica | 1 online resource (372 p.) |
| Disciplina |
152
612.8/8 616.8 |
| Soggetto topico |
Nervous system
Neurosciences Senses and sensation Viscera - Innervation |
| Soggetto genere / forma | Electronic books. |
| ISBN |
1-280-83440-4
9786610834402 0-19-803110-6 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Contents; PART I. DEFINITIONS, HISTORY, BACKGROUND; PART II. THE ESSENTIAL RECENT SCIENCE; PART III. RELATED TOPICS AND SUMMARY; References; Name Index; Subject Index |
| Record Nr. | UNINA-9910453699303321 |
Cameron Oliver G
|
||
| Oxford ; ; New York, : Oxford University Press, 2002 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Visceral sensory neuroscience [[electronic resource] ] : interoception / / Oliver G. Cameron
| Visceral sensory neuroscience [[electronic resource] ] : interoception / / Oliver G. Cameron |
| Autore | Cameron Oliver G |
| Pubbl/distr/stampa | Oxford ; ; New York, : Oxford University Press, 2002 |
| Descrizione fisica | 1 online resource (372 p.) |
| Disciplina |
152
612.8/8 616.8 |
| Soggetto topico |
Nervous system
Neurosciences Senses and sensation Viscera - Innervation |
| ISBN |
0-19-770919-2
1-280-83440-4 9786610834402 0-19-803110-6 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Contents; PART I. DEFINITIONS, HISTORY, BACKGROUND; PART II. THE ESSENTIAL RECENT SCIENCE; PART III. RELATED TOPICS AND SUMMARY; References; Name Index; Subject Index |
| Record Nr. | UNINA-9910782309403321 |
|
Cameron Oliver G
|
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| Oxford ; ; New York, : Oxford University Press, 2002 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Soggetto topico
-
Senses and sensation
(213)
- Perception (19)
- Archaeology - Methodology (9)
- Psychophysiology (9)
- Visual perception (9)