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The laboratory rat [[electronic resource] /] / edited by Mark A. Suckow, Steven H. Weisbroth, Craig L. Franklin
| The laboratory rat [[electronic resource] /] / edited by Mark A. Suckow, Steven H. Weisbroth, Craig L. Franklin |
| Edizione | [2nd ed.] |
| Pubbl/distr/stampa | Amsterdam ; ; Boston, : Elsevier, c2006 |
| Descrizione fisica | 1 online resource (929 p.) |
| Disciplina | 616/.02733 |
| Altri autori (Persone) |
SuckowMark A
WeisbrothSteven H FranklinCraig L |
| Collana | American College of Laboratory Animal Medicine series |
| Soggetto topico | Rats as laboratory animals |
| ISBN |
1-280-62843-X
9786610628438 0-08-045432-1 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Front cover; Title page; Copyright page; Table of contents; List of Contributors; Preface; Foreword; List of Reviewers for Chapters in This Volume; 1. Historical Foundations; I. ORIGIN OF THE LABORATORY RAT; A. Earliest Records; B. Earliest Experiments; II. THE WISTAR INSTITUTE; A. Background; B. Milton J. Greenman; C. Henry H. Donaldson; D. Contributions of Donaldson's Colleagues; E. The Wistar Rat Colony; F. Wistar under Edmund Farris; G. The Modern Era at Wistar; III. BEHAVIORAL RESEARCH; A. Doctoral Students at Clark University; B. Watson and Meyer; IV. NUTRITION AND BIOCHEMISTRY
A. McCollum and the McCollum-Pratt InstituteB. Osborne and Mendel; C. Henry C. Sherman; V. ENDOCRINOLOGY AND REPRODUCTIVE PHYSIOLOGY; A. Long and Evans; B. Evans and The Institute of Experimental Biology; VI. GENETICS; A. Castle and The Bussey Institution of Harvard; B. Castle's Second Career; VII. CANCER RESEARCH INSTITUTES; A. The Crocker Institute of Cancer Research; B. The Detroit Institute for Cancer Research; C. The University of Miami and Papanicolaou Cancer Research Institute; VIII. OTHER STOCKS OF RATS; A. Sprague-Dawley; B. Albany Strain C. Hunt's Caries-Susceptible and Caries-Resistant StrainsD. The Oldest Rat Stock and the PAR/Lou Strain; IX. GENEALOGY OF MAJOR RAT STOCKS AND STRAINS; X. GNOTOBIOLOGY: RATS WITHOUT MICROFLORA; A. Gustafsson at the University of Lund; B. Reyniers and The Lobund Institute; XI. SECURING THE FOUNDATIONS; A. Funding: Role of The National Institutes of Health; B. Health: Eliminating Pathogens and Nutrients as Variables; C. Genetics: Repositories and Standards; D. Information: Dissemination and Exchange; XII. EPILOGUE; ACKNOWLEDGMENTS; REFERENCES; 2. Ethical and Legal Perspectives; I. INTRODUCTION II. ETHICAL CONSIDERATIONSA. The Principles of Reduction, Replacement, and Refinement; B. Ethical Concepts and Legal Implementation; III. ENVIRONMENTAL ENRICHMENT FOR LABORATORY RATS; A. Contributions of Russell and Burch; B. Enrichment Goals; C. Testing Methods; D. Cage Size, Design and Flooring; E. Bedding, Nesting Material and Nest Boxes; F. Inanimate Objects (Toys andTubes); G. Single versus Group Housing; IV. LEGALAND REGULATORY ISSUES; A. U.S. Legislation, Policies, and Guidelines Governing Laboratory Rats; B. Reduction of Regulatory Burden in Laboratory Animal Welfare C. U.S. Animal WelfareAct ( 1966-1990)D. USDA Regulations Related to Rats, Mice and Birds; REFERENCES; 3. Taxonomy and Stocks and Strains; I. INTRODUCTION; II. TAXONOMY AND GEOGRAPHICAL DISTRIBUTION; III. ADAPTATION TO THE LABORATORY; IV. STOCKS AND STRAINS OF LABORATORY RATS; A. Outbred Stocks; B. Inbred Strains; V. NOMENCLATURE; A. Nomenclature Rules for Outbred Stocks; B. Nomenclature Rules for Inbred Strains; VI. SUMMARY; REFERENCES; 4. Morphophysiology; I. INTRODUCTION; II. GENERAL APPEARANCE; A. Head and Body; B. External Reproductive Genitalia; C. Skeletal Structure; D. Musculature E. Superficial Glands of the Head and Neck |
| Record Nr. | UNINA-9910826101003321 |
| Amsterdam ; ; Boston, : Elsevier, c2006 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Microbial and phenotypic definition of rats and mice [[electronic resource] ] : proceedings of the 1998 US/Japan Conference / / International Committee of the Institute for Laboratory Animal Research, National Research Council
| Microbial and phenotypic definition of rats and mice [[electronic resource] ] : proceedings of the 1998 US/Japan Conference / / International Committee of the Institute for Laboratory Animal Research, National Research Council |
| Pubbl/distr/stampa | Washington, D.C., : National Academy Press, 1999 |
| Descrizione fisica | 1 online resource (110 p.) |
| Disciplina | 599/.35/135 |
| Collana | The compass series |
| Soggetto topico |
Mice - Genetics
Rats - Genetics Mice as laboratory animals Rats as laboratory animals |
| Soggetto genere / forma | Electronic books. |
| ISBN |
0-309-52018-5
0-585-15401-5 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
""Front Matter""; ""Preface""; ""Contents""; ""Opening Remarks""; ""The Need for Defined Rats and Mice in Biomedical Research: Problems, Issues, and the Current State of Affairs""; ""The Need for Defined Rats and Mice in Biomedical Research: Problems, Issues, and the Current State of Affairs""; ""The Biological Integrity of Laboratory Rodents""; ""Quality Testing System for SPF Animals in Japan and Problems in the Management of Such Systems""; ""Definition of Microbiological Status of Rats and Mice / The Need for Methods of Defining Flora / International Standards for Terminology""
""Development of Rodent Pathogen Profiles and Adequacy of Detection Technology""""Current Status of Pathogen Status in Mice and Rats""; ""Genetic Background and Phenotypes in Animal Models of Human Diseases""; ""Genetic and Phenotypic Definition of Laboratory Mice and Rats / What Constitutes an Acceptable Genetic-Phenotypic Definition""; ""Phenotype Assessment Requires More Than a Casual Observation""; ""Genetic and Phenotypic Definition of Laboratory Mice and Rats / What Constitutes an Acceptable Genetic-Phenotypic Definition"" ""Genetic and Phenotypic Definition of Laboratory Mice and Rats / What Constitutes an Acceptable Genetic-Phenotypic Definition""""CIEA/NCRR/NIH Genetic and Microbiological Monitoring of Mouse and Rat Resources: Directions for the Future""; ""CIEA/NCRR/NIH Genetic and Microbiological Monitoring of Mouse and Rat Resources: Directions for the Future""; ""Closing Comments / Summary of Presentations""; ""Summary of Presentations""; ""Summary of Presentations""; ""Summary of Presentations""; ""Summary of Presentations""; ""Appendix A US/Japan Meeting""; ""Appendix B Meeting Participants"" |
| Record Nr. | UNINA-9910456116303321 |
| Washington, D.C., : National Academy Press, 1999 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Microbial and phenotypic definition of rats and mice [[electronic resource] ] : proceedings of the 1998 US/Japan Conference / / International Committee of the Institute for Laboratory Animal Research, National Research Council
| Microbial and phenotypic definition of rats and mice [[electronic resource] ] : proceedings of the 1998 US/Japan Conference / / International Committee of the Institute for Laboratory Animal Research, National Research Council |
| Pubbl/distr/stampa | Washington, D.C., : National Academy Press, 1999 |
| Descrizione fisica | 1 online resource (110 p.) |
| Disciplina | 599/.35/135 |
| Collana | The compass series |
| Soggetto topico |
Mice - Genetics
Rats - Genetics Mice as laboratory animals Rats as laboratory animals |
| ISBN |
0-309-17282-9
0-309-52018-5 0-585-15401-5 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
""Front Matter""; ""Preface""; ""Contents""; ""Opening Remarks""; ""The Need for Defined Rats and Mice in Biomedical Research: Problems, Issues, and the Current State of Affairs""; ""The Need for Defined Rats and Mice in Biomedical Research: Problems, Issues, and the Current State of Affairs""; ""The Biological Integrity of Laboratory Rodents""; ""Quality Testing System for SPF Animals in Japan and Problems in the Management of Such Systems""; ""Definition of Microbiological Status of Rats and Mice / The Need for Methods of Defining Flora / International Standards for Terminology""
""Development of Rodent Pathogen Profiles and Adequacy of Detection Technology""""Current Status of Pathogen Status in Mice and Rats""; ""Genetic Background and Phenotypes in Animal Models of Human Diseases""; ""Genetic and Phenotypic Definition of Laboratory Mice and Rats / What Constitutes an Acceptable Genetic-Phenotypic Definition""; ""Phenotype Assessment Requires More Than a Casual Observation""; ""Genetic and Phenotypic Definition of Laboratory Mice and Rats / What Constitutes an Acceptable Genetic-Phenotypic Definition"" ""Genetic and Phenotypic Definition of Laboratory Mice and Rats / What Constitutes an Acceptable Genetic-Phenotypic Definition""""CIEA/NCRR/NIH Genetic and Microbiological Monitoring of Mouse and Rat Resources: Directions for the Future""; ""CIEA/NCRR/NIH Genetic and Microbiological Monitoring of Mouse and Rat Resources: Directions for the Future""; ""Closing Comments / Summary of Presentations""; ""Summary of Presentations""; ""Summary of Presentations""; ""Summary of Presentations""; ""Summary of Presentations""; ""Appendix A US/Japan Meeting""; ""Appendix B Meeting Participants"" |
| Record Nr. | UNINA-9910778746203321 |
| Washington, D.C., : National Academy Press, 1999 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Microbial and phenotypic definition of rats and mice [[electronic resource] ] : proceedings of the 1998 US/Japan Conference / / International Committee of the Institute for Laboratory Animal Research, National Research Council
| Microbial and phenotypic definition of rats and mice [[electronic resource] ] : proceedings of the 1998 US/Japan Conference / / International Committee of the Institute for Laboratory Animal Research, National Research Council |
| Pubbl/distr/stampa | Washington, D.C., : National Academy Press, 1999 |
| Descrizione fisica | 1 online resource (110 p.) |
| Disciplina | 599/.35/135 |
| Collana | The compass series |
| Soggetto topico |
Mice - Genetics
Rats - Genetics Mice as laboratory animals Rats as laboratory animals |
| ISBN |
0-309-17282-9
0-309-52018-5 0-585-15401-5 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
""Front Matter""; ""Preface""; ""Contents""; ""Opening Remarks""; ""The Need for Defined Rats and Mice in Biomedical Research: Problems, Issues, and the Current State of Affairs""; ""The Need for Defined Rats and Mice in Biomedical Research: Problems, Issues, and the Current State of Affairs""; ""The Biological Integrity of Laboratory Rodents""; ""Quality Testing System for SPF Animals in Japan and Problems in the Management of Such Systems""; ""Definition of Microbiological Status of Rats and Mice / The Need for Methods of Defining Flora / International Standards for Terminology""
""Development of Rodent Pathogen Profiles and Adequacy of Detection Technology""""Current Status of Pathogen Status in Mice and Rats""; ""Genetic Background and Phenotypes in Animal Models of Human Diseases""; ""Genetic and Phenotypic Definition of Laboratory Mice and Rats / What Constitutes an Acceptable Genetic-Phenotypic Definition""; ""Phenotype Assessment Requires More Than a Casual Observation""; ""Genetic and Phenotypic Definition of Laboratory Mice and Rats / What Constitutes an Acceptable Genetic-Phenotypic Definition"" ""Genetic and Phenotypic Definition of Laboratory Mice and Rats / What Constitutes an Acceptable Genetic-Phenotypic Definition""""CIEA/NCRR/NIH Genetic and Microbiological Monitoring of Mouse and Rat Resources: Directions for the Future""; ""CIEA/NCRR/NIH Genetic and Microbiological Monitoring of Mouse and Rat Resources: Directions for the Future""; ""Closing Comments / Summary of Presentations""; ""Summary of Presentations""; ""Summary of Presentations""; ""Summary of Presentations""; ""Summary of Presentations""; ""Appendix A US/Japan Meeting""; ""Appendix B Meeting Participants"" |
| Record Nr. | UNINA-9910816117203321 |
| Washington, D.C., : National Academy Press, 1999 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
