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QSAR & combinatorial science
| QSAR & combinatorial science |
| Pubbl/distr/stampa | Weinheim, Germany, : Wiley-VCH Verlag, ©2003- |
| Descrizione fisica | 1 online resource |
| Soggetto topico |
QSAR (Biochemistry)
Structure-activity relationships (Biochemistry) Drugs - Structure-activity relationships Quantitative Structure-Activity Relationship Combinatorial Chemistry Techniques Biology Pharmacology Relations structure-activité quantitatives (Biochimie) Relations structure-activité (Biochimie) Médicaments - Relations structure-activité |
| Soggetto genere / forma |
Periodical
Abstracts. Periodicals. |
| Soggetto non controllato | Pharmacy, Therapeutics, & Pharmacology |
| ISSN | 1611-0218 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Periodico |
| Lingua di pubblicazione | eng |
| Altri titoli varianti |
Quantitative structure-activity relationships & combinatorial science
QSAR and combinatorial science QSAR & combinatorial science with abstract service QCS Quantitative structure-activity relationships |
| Record Nr. | UNINA-9910216941503321 |
| Weinheim, Germany, : Wiley-VCH Verlag, ©2003- | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
QSAR : Hansch analysis and related approaches [[electronic resource] /] / by Hugo Kubinyi
| QSAR : Hansch analysis and related approaches [[electronic resource] /] / by Hugo Kubinyi |
| Autore | Kubinyi Hugo |
| Pubbl/distr/stampa | Weinheim ; ; New York, : VCH, c1993 |
| Descrizione fisica | 1 online resource (254 p.) |
| Disciplina |
572.072
615 615.1901 |
| Collana | Methods and principles in medicinal chemistry |
| Soggetto topico |
QSAR (Biochemistry)
Pharmaceutical chemistry |
| Soggetto genere / forma | Electronic books. |
| ISBN |
1-281-75888-4
9786611758882 3-527-61682-9 3-527-61683-7 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
QSAR: Hansch Analysis and Related Approaches; Content; 1. Introduction; 1.1. History and Development of QSAR; 1.2. Drug-Receptor Interactions; 2. Biological Data. The Additivity of Group Contributions; 3. Parameters; 3.1. Lipophilicity Parameters; 3.2. The Measurement of Partition Coefficients and Related Lipophilicity Parameters; 3.3. Lipophilicity Contributions and the Calculation of Partition Coefficients; 3.4. Polarizability Parameters; 3.5. Electronic Parameters; 3.6. Steric Parameters; 3.7. Other Parameters; 3.8. Indicator Variables; 4. Quantitative Models
4.1. The Extrathermodynamic Approach (Hansch Analysis)4.2. The Additivity Model (Free Wilson Analysis); 4.3. The Relationships between Hansch and Free Wilson Analysis (The Mixed Approach); 4.4. Nonlinear Relationships; 4.5. Dissociation and Ionization of Acids and Bases; 4.6. Other QSAR Approaches; 5. Statistical Methods; 5.1. Regression Analysis; 5.2. The Significance and Validity of QSAR Regression Equations; 5.3. Partial Least Squares (PLS) Analysis and Other Multivariate Statistical Methods; 6. Design of Test Series in QSAR; 7. Applications of Hansch Analysis; 7.1. Enzyme Inhibition 7.2. Other in vitro Data7.3. Pharmacokinetic Data; 7.4. Other Biological Data; 7.5. Activity-Activity Relationships; 8. Applications of Free Wilson Analysis and Related Models; 9. 3D QSAR Approaches; 9.1. Stereochemistry and Drug Action; 9.2. Active Site Interaction Models; 9.3. Comparative Molecular Field Analysis (CoMFA); 9.4. Molecular Similarity QSAR Analyses; 10. Summary and Conclusions; References; Index |
| Record Nr. | UNINA-9910144132603321 |
Kubinyi Hugo
|
||
| Weinheim ; ; New York, : VCH, c1993 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
QSAR : Hansch analysis and related approaches [[electronic resource] /] / by Hugo Kubinyi
| QSAR : Hansch analysis and related approaches [[electronic resource] /] / by Hugo Kubinyi |
| Autore | Kubinyi Hugo |
| Pubbl/distr/stampa | Weinheim ; ; New York, : VCH, c1993 |
| Descrizione fisica | 1 online resource (254 p.) |
| Disciplina |
572.072
615 615.1901 |
| Collana | Methods and principles in medicinal chemistry |
| Soggetto topico |
QSAR (Biochemistry)
Pharmaceutical chemistry |
| ISBN |
1-281-75888-4
9786611758882 3-527-61682-9 3-527-61683-7 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
QSAR: Hansch Analysis and Related Approaches; Content; 1. Introduction; 1.1. History and Development of QSAR; 1.2. Drug-Receptor Interactions; 2. Biological Data. The Additivity of Group Contributions; 3. Parameters; 3.1. Lipophilicity Parameters; 3.2. The Measurement of Partition Coefficients and Related Lipophilicity Parameters; 3.3. Lipophilicity Contributions and the Calculation of Partition Coefficients; 3.4. Polarizability Parameters; 3.5. Electronic Parameters; 3.6. Steric Parameters; 3.7. Other Parameters; 3.8. Indicator Variables; 4. Quantitative Models
4.1. The Extrathermodynamic Approach (Hansch Analysis)4.2. The Additivity Model (Free Wilson Analysis); 4.3. The Relationships between Hansch and Free Wilson Analysis (The Mixed Approach); 4.4. Nonlinear Relationships; 4.5. Dissociation and Ionization of Acids and Bases; 4.6. Other QSAR Approaches; 5. Statistical Methods; 5.1. Regression Analysis; 5.2. The Significance and Validity of QSAR Regression Equations; 5.3. Partial Least Squares (PLS) Analysis and Other Multivariate Statistical Methods; 6. Design of Test Series in QSAR; 7. Applications of Hansch Analysis; 7.1. Enzyme Inhibition 7.2. Other in vitro Data7.3. Pharmacokinetic Data; 7.4. Other Biological Data; 7.5. Activity-Activity Relationships; 8. Applications of Free Wilson Analysis and Related Models; 9. 3D QSAR Approaches; 9.1. Stereochemistry and Drug Action; 9.2. Active Site Interaction Models; 9.3. Comparative Molecular Field Analysis (CoMFA); 9.4. Molecular Similarity QSAR Analyses; 10. Summary and Conclusions; References; Index |
| Record Nr. | UNISA-996218390403316 |
|
Kubinyi Hugo
|
||
| Weinheim ; ; New York, : VCH, c1993 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. di Salerno | ||
| ||
QSAR : Hansch analysis and related approaches [[electronic resource] /] / by Hugo Kubinyi
| QSAR : Hansch analysis and related approaches [[electronic resource] /] / by Hugo Kubinyi |
| Autore | Kubinyi Hugo |
| Pubbl/distr/stampa | Weinheim ; ; New York, : VCH, c1993 |
| Descrizione fisica | 1 online resource (254 p.) |
| Disciplina |
572.072
615 615.1901 |
| Collana | Methods and principles in medicinal chemistry |
| Soggetto topico |
QSAR (Biochemistry)
Pharmaceutical chemistry |
| ISBN |
1-281-75888-4
9786611758882 3-527-61682-9 3-527-61683-7 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
QSAR: Hansch Analysis and Related Approaches; Content; 1. Introduction; 1.1. History and Development of QSAR; 1.2. Drug-Receptor Interactions; 2. Biological Data. The Additivity of Group Contributions; 3. Parameters; 3.1. Lipophilicity Parameters; 3.2. The Measurement of Partition Coefficients and Related Lipophilicity Parameters; 3.3. Lipophilicity Contributions and the Calculation of Partition Coefficients; 3.4. Polarizability Parameters; 3.5. Electronic Parameters; 3.6. Steric Parameters; 3.7. Other Parameters; 3.8. Indicator Variables; 4. Quantitative Models
4.1. The Extrathermodynamic Approach (Hansch Analysis)4.2. The Additivity Model (Free Wilson Analysis); 4.3. The Relationships between Hansch and Free Wilson Analysis (The Mixed Approach); 4.4. Nonlinear Relationships; 4.5. Dissociation and Ionization of Acids and Bases; 4.6. Other QSAR Approaches; 5. Statistical Methods; 5.1. Regression Analysis; 5.2. The Significance and Validity of QSAR Regression Equations; 5.3. Partial Least Squares (PLS) Analysis and Other Multivariate Statistical Methods; 6. Design of Test Series in QSAR; 7. Applications of Hansch Analysis; 7.1. Enzyme Inhibition 7.2. Other in vitro Data7.3. Pharmacokinetic Data; 7.4. Other Biological Data; 7.5. Activity-Activity Relationships; 8. Applications of Free Wilson Analysis and Related Models; 9. 3D QSAR Approaches; 9.1. Stereochemistry and Drug Action; 9.2. Active Site Interaction Models; 9.3. Comparative Molecular Field Analysis (CoMFA); 9.4. Molecular Similarity QSAR Analyses; 10. Summary and Conclusions; References; Index |
| Record Nr. | UNINA-9910830089003321 |
|
Kubinyi Hugo
|
||
| Weinheim ; ; New York, : VCH, c1993 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
QSAR : Hansch analysis and related approaches [[electronic resource] /] / by Hugo Kubinyi
| QSAR : Hansch analysis and related approaches [[electronic resource] /] / by Hugo Kubinyi |
| Autore | Kubinyi Hugo |
| Pubbl/distr/stampa | Weinheim ; ; New York, : VCH, c1993 |
| Descrizione fisica | 1 online resource (254 p.) |
| Disciplina |
572.072
615 615.1901 |
| Collana | Methods and principles in medicinal chemistry |
| Soggetto topico |
QSAR (Biochemistry)
Pharmaceutical chemistry |
| ISBN |
1-281-75888-4
9786611758882 3-527-61682-9 3-527-61683-7 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
QSAR: Hansch Analysis and Related Approaches; Content; 1. Introduction; 1.1. History and Development of QSAR; 1.2. Drug-Receptor Interactions; 2. Biological Data. The Additivity of Group Contributions; 3. Parameters; 3.1. Lipophilicity Parameters; 3.2. The Measurement of Partition Coefficients and Related Lipophilicity Parameters; 3.3. Lipophilicity Contributions and the Calculation of Partition Coefficients; 3.4. Polarizability Parameters; 3.5. Electronic Parameters; 3.6. Steric Parameters; 3.7. Other Parameters; 3.8. Indicator Variables; 4. Quantitative Models
4.1. The Extrathermodynamic Approach (Hansch Analysis)4.2. The Additivity Model (Free Wilson Analysis); 4.3. The Relationships between Hansch and Free Wilson Analysis (The Mixed Approach); 4.4. Nonlinear Relationships; 4.5. Dissociation and Ionization of Acids and Bases; 4.6. Other QSAR Approaches; 5. Statistical Methods; 5.1. Regression Analysis; 5.2. The Significance and Validity of QSAR Regression Equations; 5.3. Partial Least Squares (PLS) Analysis and Other Multivariate Statistical Methods; 6. Design of Test Series in QSAR; 7. Applications of Hansch Analysis; 7.1. Enzyme Inhibition 7.2. Other in vitro Data7.3. Pharmacokinetic Data; 7.4. Other Biological Data; 7.5. Activity-Activity Relationships; 8. Applications of Free Wilson Analysis and Related Models; 9. 3D QSAR Approaches; 9.1. Stereochemistry and Drug Action; 9.2. Active Site Interaction Models; 9.3. Comparative Molecular Field Analysis (CoMFA); 9.4. Molecular Similarity QSAR Analyses; 10. Summary and Conclusions; References; Index |
| Record Nr. | UNINA-9910841710503321 |
|
Kubinyi Hugo
|
||
| Weinheim ; ; New York, : VCH, c1993 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Quantitative structure-activity relationship / / edited by Fatma Kandemirli
| Quantitative structure-activity relationship / / edited by Fatma Kandemirli |
| Pubbl/distr/stampa | Rijeka, Croatia : , : IntechOpen, , [2017] |
| Descrizione fisica | 1 online resource (88 pages) : illustrations |
| Disciplina | 615.19 |
| Soggetto topico | QSAR (Biochemistry) |
| ISBN |
953-51-4680-7
953-51-3410-8 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910317851803321 |
| Rijeka, Croatia : , : IntechOpen, , [2017] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Quantitative structure-activity relationships
| Quantitative structure-activity relationships |
| Pubbl/distr/stampa | Weinheim, Fed. Rep. of Germany, : Wiley-VCH, -2002 |
| Soggetto topico |
Drugs - Structure-activity relationships
Xenobiotics - Structure-activity relationships QSAR (Biochemistry) Biology Chemistry Computer Graphics Models, Molecular Pharmacology Structure-Activity Relationship Médicaments - Relations structure-activité Xénobiotiques - Relations structure-activité Relations structure-activité quantitatives (Biochimie) |
| Soggetto genere / forma |
Abstracts.
Periodical |
| ISSN | 1521-3838 |
| Formato | Materiale a stampa |
| Livello bibliografico | Periodico |
| Lingua di pubblicazione | eng |
| Altri titoli varianti |
QSAR
Quantitative structure-activity relationships QSAR with abstract service Quantitative Structure Activity Relationships (currently QSAR & Combinatorial Science in 2003) Quantitative Structure Activity Relationships |
| Record Nr. | UNINA-9910216954303321 |
| Weinheim, Fed. Rep. of Germany, : Wiley-VCH, -2002 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Quantitative structure-activity relationships
| Quantitative structure-activity relationships |
| Pubbl/distr/stampa | Weinheim, Fed. Rep. of Germany, : Wiley-VCH, -2002 |
| Soggetto topico |
Drugs - Structure-activity relationships
Xenobiotics - Structure-activity relationships QSAR (Biochemistry) Biology Chemistry Computer Graphics Models, Molecular Pharmacology Structure-Activity Relationship Médicaments - Relations structure-activité Xénobiotiques - Relations structure-activité Relations structure-activité quantitatives (Biochimie) |
| Soggetto genere / forma |
Abstracts.
Periodical |
| ISSN | 1521-3838 |
| Formato | Materiale a stampa |
| Livello bibliografico | Periodico |
| Lingua di pubblicazione | eng |
| Altri titoli varianti |
QSAR
Quantitative structure-activity relationships QSAR with abstract service Quantitative Structure Activity Relationships (currently QSAR & Combinatorial Science in 2003) Quantitative Structure Activity Relationships |
| Record Nr. | UNISA-996205738503316 |
| Weinheim, Fed. Rep. of Germany, : Wiley-VCH, -2002 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. di Salerno | ||
| ||
Recent trends on QSAR in the pharmaeutical perceptions [[electronic resource] /] / edited by Mahmud Tareq Hassan Khan
| Recent trends on QSAR in the pharmaeutical perceptions [[electronic resource] /] / edited by Mahmud Tareq Hassan Khan |
| Pubbl/distr/stampa | [Oak Park, Ill.], : Bentham eBooks, [2012] |
| Descrizione fisica | 1 online resource (407 p.) |
| Disciplina | 614.35 |
| Altri autori (Persone) | KhanMahmud Tareq Hassan |
| Soggetto topico | QSAR (Biochemistry) |
| Soggetto genere / forma | Electronic books. |
| ISBN | 1-60805-379-2 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Cover; TItle; EUL; Contents; Foreword by Alexandru T; Foreword by Roberto Todeschini; Preface; List of Contributors; Chapter 01; Chapter 02; Chapter 03; Chapter 04; Chapter 05; Chapter 06; Chapter 07; Chapter 08; Chapter 09; Chapter 10; Chapter 11; Chapter 12 |
| Record Nr. | UNINA-9910465408403321 |
| [Oak Park, Ill.], : Bentham eBooks, [2012] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Recent trends on QSAR in the pharmaeutical perceptions [[electronic resource] /] / edited by Mahmud Tareq Hassan Khan
| Recent trends on QSAR in the pharmaeutical perceptions [[electronic resource] /] / edited by Mahmud Tareq Hassan Khan |
| Pubbl/distr/stampa | [Oak Park, Ill.], : Bentham eBooks, [2012] |
| Descrizione fisica | 1 online resource (407 p.) |
| Disciplina | 614.35 |
| Altri autori (Persone) | KhanMahmud Tareq Hassan |
| Soggetto topico | QSAR (Biochemistry) |
| ISBN | 1-60805-379-2 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Cover; TItle; EUL; Contents; Foreword by Alexandru T; Foreword by Roberto Todeschini; Preface; List of Contributors; Chapter 01; Chapter 02; Chapter 03; Chapter 04; Chapter 05; Chapter 06; Chapter 07; Chapter 08; Chapter 09; Chapter 10; Chapter 11; Chapter 12 |
| Record Nr. | UNINA-9910792096803321 |
| [Oak Park, Ill.], : Bentham eBooks, [2012] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
