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Introduction to Biomolecular Structure and Biophysics : Basics of Biophysics / / edited by Gauri Misra
| Introduction to Biomolecular Structure and Biophysics : Basics of Biophysics / / edited by Gauri Misra |
| Edizione | [1st ed. 2017.] |
| Pubbl/distr/stampa | Singapore : , : Springer Singapore : , : Imprint : Springer, , 2017 |
| Descrizione fisica | 1 online resource (XVII, 274 p. 133 illus., 78 illus. in color.) |
| Disciplina | 610.28 |
| Soggetto topico |
Biomedical engineering
Biophysics Biological physics Nucleic acids Proteins Medical genetics Biomedical Engineering/Biotechnology Biological and Medical Physics, Biophysics Nucleic Acid Chemistry Protein Science Gene Function Protein-Ligand Interactions |
| ISBN | 981-10-4968-8 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Principles of protein structure and function -- Protein folding -- Nucleic acid structure and functions -- Higher order nucleic acid structures -- Molecular Interactions -- Lipid and membrane structures -- Chapter 7. Membrane biophysics -- Techniques in Biophysics -- Advance techniques in Biophysics. |
| Record Nr. | UNINA-9910253938003321 |
| Singapore : , : Springer Singapore : , : Imprint : Springer, , 2017 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Iron Acquisition by the Genus Mycobacterium : History, Mechanisms, Role of Siderocalin, Anti-Tuberculosis Drug Development / / edited by B. Rowe Byers
| Iron Acquisition by the Genus Mycobacterium : History, Mechanisms, Role of Siderocalin, Anti-Tuberculosis Drug Development / / edited by B. Rowe Byers |
| Edizione | [1st ed. 2013.] |
| Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2013 |
| Descrizione fisica | 1 online resource (96 p.) |
| Disciplina | 572.517 |
| Collana | SpringerBriefs in Biometals |
| Soggetto topico |
Microbiology
Proteins Inorganic chemistry Bioorganic chemistry Infectious diseases Protein-Ligand Interactions Inorganic Chemistry Bioorganic Chemistry Infectious Diseases |
| ISBN | 3-319-00303-8 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | A History of Iron Metabolism in the Mycobacteria -- Mycobacterial Iron Uptake Mechanisms -- Siderocalin Combats Mycobacterial Infections -- Design of Anti-TB Drugs Using the Iron Uptake Platform. |
| Record Nr. | UNINA-9910741183103321 |
| Cham : , : Springer International Publishing : , : Imprint : Springer, , 2013 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Kinesins and Cancer / / edited by Frank Kozielski, FSB
| Kinesins and Cancer / / edited by Frank Kozielski, FSB |
| Edizione | [1st ed. 2015.] |
| Pubbl/distr/stampa | Dordrecht : , : Springer Netherlands : , : Imprint : Springer, , 2015 |
| Descrizione fisica | 1 online resource (276 p.) |
| Disciplina | 572/.6 |
| Soggetto topico |
Cancer research
Cell biology Medicinal chemistry Proteins Oncology Cancer Research Cell Biology Medicinal Chemistry Protein-Ligand Interactions Oncology |
| ISBN | 94-017-9732-3 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Preface -- The kinesin superfamily -- The discovery and development of Eg5 inhibitors for the clinic -- Mechanism of action of Eg5 inhibitors -- Clinical trials of mitotic kinesin inhibitors -- Kif15; a useful target for anti-cancer therapy?.- Down-regulating CENP-E activity: for better or for worse -- The human kinesin-14 motor KifC1/HSET is an attractive anti-cancer drug target.-Kinesin-13 Microtubule Depolymerizing Proteins as targets for cancer therapy -- Chromokinesins in genome maintenance and cancer -- Kif14: a clinically relevant kinesin and potential target for cancer therapy -- Kinesin-8 members and their potential as biomarker or therapeutic target -- The kinesin-6 members MKLP1, MKLP2 and MPP -- Non-motor spindle proteins as cancer chemotherapy targets -- Inhibitors of mitotic kinesins for cancer treatment: consequences for neurons -- Index. |
| Record Nr. | UNINA-9910298272403321 |
| Dordrecht : , : Springer Netherlands : , : Imprint : Springer, , 2015 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Kinetics of Enzyme-Modifier Interactions : Selected Topics in the Theory and Diagnosis of Inhibition and Activation Mechanisms / / by Antonio Baici
| Kinetics of Enzyme-Modifier Interactions : Selected Topics in the Theory and Diagnosis of Inhibition and Activation Mechanisms / / by Antonio Baici |
| Autore | Baici Antonio |
| Edizione | [1st ed. 2015.] |
| Pubbl/distr/stampa | Vienna : , : Springer Vienna : , : Imprint : Springer, , 2015 |
| Descrizione fisica | 1 online resource (503 p.) |
| Disciplina |
570
570285 571.4 572.6 |
| Soggetto topico |
Enzymology
Proteins Bioinformatics Computational biology Biophysics Biological physics Protein-Ligand Interactions Computer Appl. in Life Sciences Biological and Medical Physics, Biophysics |
| ISBN | 3-7091-1402-0 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Basic Knowledge -- The General Modifier Mechanism -- Taxonomy of Enzyme-Modifier Interactions and the Specific Velocity Plot -- Complements to Enzyme-Modifier Interactions -- The Basic Mechanisms of Inhibition and Nonessential Activation -- Multiple Enzyme-Modifier Interactions -- Multiple Interactions: Essential Activation and Liberation -- Slow-Onset Enzyme Inhibition -- Enzyme Inactivation with a Note on the Significance of Slow Modification Processes.- Dichotomous Keys to Enzyme-Modification Mechanisms. . |
| Record Nr. | UNINA-9910298269003321 |
Baici Antonio
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| Vienna : , : Springer Vienna : , : Imprint : Springer, , 2015 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Mechanism of Functional Expression of the Molecular Machines / / by Masahiro Kinoshita
| Mechanism of Functional Expression of the Molecular Machines / / by Masahiro Kinoshita |
| Autore | Kinoshita Masahiro |
| Edizione | [1st ed. 2016.] |
| Pubbl/distr/stampa | Singapore : , : Springer Singapore : , : Imprint : Springer, , 2016 |
| Descrizione fisica | 1 online resource (X, 70 p. 30 illus., 24 illus. in color.) |
| Disciplina | 539.6 |
| Collana | SpringerBriefs in Molecular Science |
| Soggetto topico |
Physical chemistry
Biophysics Biological physics Proteins Statistical physics Dynamical systems Physical Chemistry Biological and Medical Physics, Biophysics Protein-Ligand Interactions Complex Systems Statistical Physics and Dynamical Systems |
| ISBN | 981-10-1486-8 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Introduction -- Importance of Translational, Configurational Entropy of Water -- Molecular Machines -- Concluding Remarks: Mechanism of Functional Expression Common in the Molecular Machines. |
| Record Nr. | UNINA-9910254051003321 |
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Kinoshita Masahiro
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| Singapore : , : Springer Singapore : , : Imprint : Springer, , 2016 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Membrane Biophysics / / by Mohammad Ashrafuzzaman, Jack A. Tuszynski
| Membrane Biophysics / / by Mohammad Ashrafuzzaman, Jack A. Tuszynski |
| Autore | Ashrafuzzaman Mohammad |
| Edizione | [1st ed. 2013.] |
| Pubbl/distr/stampa | Berlin, Heidelberg : , : Springer Berlin Heidelberg : , : Imprint : Springer, , 2013 |
| Descrizione fisica | 1 online resource (189 p.) |
| Disciplina | 571.64 |
| Collana | Biological and Medical Physics, Biomedical Engineering |
| Soggetto topico |
Biophysics
Biological physics Cell membranes Physical chemistry Physics Nanoscale science Nanoscience Nanostructures Proteins Biological and Medical Physics, Biophysics Membrane Biology Physical Chemistry Numerical and Computational Physics, Simulation Nanoscale Science and Technology Membranes cel·lulars Protein-Ligand Interactions |
| ISBN |
1-283-62668-3
9786613939135 3-642-16105-7 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Structure of Membranes -- Lipids in Membranes -- The Membrane as a Transporter.- Lipid Bilayer-Membrane Protein Coupling -- Membrane-Based Nanotechnology and Drug Delivery -- Membrane-Related Diseases. |
| Record Nr. | UNINA-9910438106303321 |
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Ashrafuzzaman Mohammad
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| Berlin, Heidelberg : , : Springer Berlin Heidelberg : , : Imprint : Springer, , 2013 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Membrane Dynamics and Calcium Signaling / / edited by Joachim Krebs
| Membrane Dynamics and Calcium Signaling / / edited by Joachim Krebs |
| Edizione | [1st ed. 2017.] |
| Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2017 |
| Descrizione fisica | 1 online resource (409 pages) |
| Disciplina | 572.516 |
| Collana | Advances in Experimental Medicine and Biology |
| Soggetto topico |
Cell membranes
Proteins Biophysics Biological physics Membrane Biology Protein-Ligand Interactions Biological and Medical Physics, Biophysics |
| ISBN | 3-319-55858-7 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | PMCA -- Calcium channel -- Sodium/calcium exchanger -- Endoplasmic Reticulum -- SERCA Pump H -- IP3R -- IP3R -- RyR -- History of the SOCE concept -- STIM/Orai -- TRPC channel -- MCU complex -- VDAC -- Annexins -- Cytokinesis and Ca2+ signaling. |
| Record Nr. | UNINA-9910279578403321 |
| Cham : , : Springer International Publishing : , : Imprint : Springer, , 2017 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Molecular Mechanisms of Notch Signaling / / edited by Tilman Borggrefe, Benedetto Daniele Giaimo
| Molecular Mechanisms of Notch Signaling / / edited by Tilman Borggrefe, Benedetto Daniele Giaimo |
| Edizione | [1st ed. 2018.] |
| Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2018 |
| Descrizione fisica | 1 online resource (XXVII, 398 p. 59 illus., 56 illus. in color.) |
| Disciplina | 572.696 |
| Collana | Advances in Experimental Medicine and Biology |
| Soggetto topico |
Proteins
Receptors Protein-Ligand Interactions Protein Structure |
| ISBN | 3-319-89512-5 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Introduction to Molecular Mechanisms in Notch Signal Transduction and Disease Pathogenesis -- Structural insights into Notch receptor-ligand interactions -- The Molecular Mechanism of Notch Activation -- Regulation of Notch Function by O-Glycosylation -- Modeling the Notch response -- Endocytic trafficking of the Notch receptor -- The Notch Interactome: complexity in signaling circuitry -- Integration of Drosophila and Human Genetics to understand Notch signaling related diseases -- Mechanisms of non-canonical signaling in health and disease: Diversity to take therapy up a Notch? -- The Notch3 receptor and its intracellular signaling-dependent oncogenic mechanisms -- Notch and neurogenesis -- Notch and stem cells -- Oscillatory control of Notch signaling in development -- CSL-associated corepressor and coactivator complexes -- Notch and senescence -- Control of blood vessel formation by Notch signaling -- Notch and T cell function – a complex tale -- Notch in leukemia. |
| Record Nr. | UNINA-9910298403503321 |
| Cham : , : Springer International Publishing : , : Imprint : Springer, , 2018 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Molecular Science of Fluctuations Toward Biological Functions / / edited by Mazahide Terazima, Mikio Kataoka, Ryuichi Ueoka, Yuko Okamoto
| Molecular Science of Fluctuations Toward Biological Functions / / edited by Mazahide Terazima, Mikio Kataoka, Ryuichi Ueoka, Yuko Okamoto |
| Edizione | [1st ed. 2016.] |
| Pubbl/distr/stampa | Tokyo : , : Springer Japan : , : Imprint : Springer, , 2016 |
| Descrizione fisica | 1 online resource (276 p.) |
| Disciplina | 540 |
| Soggetto topico |
Bioorganic chemistry
Proteins Biophysics Biological physics Physical chemistry Bioinformatics Computational biology Molecular biology Bioorganic Chemistry Protein-Ligand Interactions Biological and Medical Physics, Biophysics Physical Chemistry Computer Appl. in Life Sciences Molecular Medicine |
| ISBN | 4-431-55840-3 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Time-resolved detection of protein fluctuations during reactions -- Pressure perturbation: A prime tool to study conformational substates and volume fluctuations of biomolecular assemblies -- Watching a signaling protein function in real time via picosecond time-resolved Laue crystallography -- NMR explorations of biomolecular systems with rapid conformational exchanges -- Site-specific incorporation of fluorescent nonnatural amino acids in-to proteins and its application to fluorescence analysis of proteins -- Unfoldomes and unfoldomics: introducing intrinsically disordered proteins -- Structure, dynamics and function of staphylococcal nuclease -- Theory of molecular recognition and structural fluctuation of biomolecules -- Structural fluctuations of proteins in folding and ligand docking studied by replica-exchange simulations -- Spatio-temporal fluctuations of protein folding in living cells -- Membrane-targeted nanotherapy with hybrid liposomes for cancer cells leading to apoptosis -- Anti-tumor complexes formed by oleic acid and molten globule intermediates of proteins. |
| Record Nr. | UNINA-9910254023603321 |
| Tokyo : , : Springer Japan : , : Imprint : Springer, , 2016 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Multifaceted Roles of Crystallography in Modern Drug Discovery / / edited by Giovanna Scapin, Disha Patel, Eddy Arnold
| Multifaceted Roles of Crystallography in Modern Drug Discovery / / edited by Giovanna Scapin, Disha Patel, Eddy Arnold |
| Edizione | [1st ed. 2015.] |
| Pubbl/distr/stampa | Dordrecht : , : Springer Netherlands : , : Imprint : Springer, , 2015 |
| Descrizione fisica | 1 online resource (XI, 240 p. 107 illus., 89 illus. in color.) |
| Disciplina | 530.41 |
| Collana | NATO Science for Peace and Security Series A: Chemistry and Biology |
| Soggetto topico |
Proteins
Medicinal chemistry Molecular biology Chemistry, Physical and theoretical Crystallography Protein-Ligand Interactions Medicinal Chemistry Molecular Medicine Theoretical and Computational Chemistry Crystallography and Scattering Methods |
| ISBN | 94-017-9719-6 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Preface -- List of Contributors -- Engineering G Protein-Coupled Receptors for Drug Design -- Structural Insights into Activation and Allosteric Modulation of G Protein-Coupled Receptors -- Epigenetic Drug Discovery -- Crystallography and Biopharmaceuticals -- Structural Chemistry and Molecular Modeling in the Design of DPP4 Inhibitors -- Considerations for Structure-Based Drug Design Targeting HIV-1 Reverse Transcriptase.-Protein-Ligand Interactions as the Basis for Drug Action -- The Protein Data Bank: Overview and Tools for Drug Discovery -- Small Molecule Crystal Structures in Drug Discovery -- Protein Aggregation and its Prediction -- Importance of Protonation States for the Binding of Ligands to Pharmaceutical Targets -- Protein-Protein Interactions: Structures and Druggability -- Achieving High Quality Ligand Chemistry in Protein-Ligand Crystal Structures for Drug Design -- Molecular Obesity, Potency and Other Addictions in Drug Discovery -- Adventures in Small Molecule Fragment Screening by X-ray Crystallography for Drug Discovery -- Structure-Based Drug Design to Perturb Function of a tRNA-Modifying Enzyme by Active Site and Protein-Protein Interface Inhibition -- Molecular Interaction Analysis for Discovery of Drugs Targeting Enzymes and for Resolving Biological Function. |
| Record Nr. | UNINA-9910298273503321 |
| Dordrecht : , : Springer Netherlands : , : Imprint : Springer, , 2015 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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