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Degradable polymers for skeletal implants [[electronic resource] /] / Paul I.J.M. Wuisman and Theo H. Smit, editors
| Degradable polymers for skeletal implants [[electronic resource] /] / Paul I.J.M. Wuisman and Theo H. Smit, editors |
| Autore | Wuisman Paul I. J. M |
| Pubbl/distr/stampa | New York, : Nova Science Publishers, c2009 |
| Descrizione fisica | 1 online resource (407 p.) |
| Disciplina | 610.28/4 |
| Altri autori (Persone) |
WuismanPaul I. J. M
SmitTheo M |
| Soggetto topico |
Polymers in medicine
Polyesters - Biocompatibility Orthopedic implants |
| ISBN | 1-61728-357-6 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
""DEGRADABLE POLYMERS FOR SKELETAL IMPLANTS""; ""DEDICATION""; ""CONTENTS""; ""PREFACE""; ""ABOUT THE EDITORS""; ""PART I: BASIC SCIENCE AND ENGINEERING""; ""THE MOLECULAR STRUCTURE OF DEGRADABLE POLYMERS""; ""ABSTRACT""; ""INTRODUCTION""; ""BIODEGRADABLE POLYMERS""; ""THE CHEMISTRY OF ESTERS""; ""THE CHEMISTRY OF POLYESTERS""; ""POLYMER TERMINOLOGY""; ""BIOCOMPATIBILITY OF BIODEGRADABLE POLYMERS""; ""POLYESTERS AS BIOMEDICAL MATERIALS""; ""1. Poly(lactic acid), PLA""; ""2. Poly(glycolic acid), PGA""; ""3. Copolymers of PGA and PLA, Poly(lactide-co-glycolide), PLGA""
""4. Bacterial Polyesters""""5. Other Polyesters""; ""6. Polyurethanes""; ""BIODEGRADATION""; ""REFERENCES""; ""TIME-DEPENDENT FAILURE IN LOAD-BEARING POLYMERS. A POTENTIAL HAZARD IN STRUCTURAL APPLICATIONS OF POLYLACTIDES""; ""ABSTRACT""; ""INTRODUCTION""; ""DELAYED FAILURE IN POLYMERS""; ""Phenomenology""; ""Origin""; ""Intrinsic Deformation Behavior""; ""Predictability of Failure""; ""Delayed Failure of Polylactides""; ""Materials""; ""Mechanical Evaluation""; ""Long-Term Performance of PLA's Vs other Glassy Polymers""; ""Influence of Molecular Degradation""; ""CONCLUDING REMARKS"" ""REFERENCES""""POLY(LACTIDE)S AND THEIR COPOLYMERS: PHYSICAL PROPERTIES AND HYDROLYTIC DEGRADATION""; ""ABSTRACT""; ""INTRODUCTION""; ""1. SYNTHESIS""; ""2. MECHANICAL PROPERTIES""; ""2.1. Effect of Molecular Characteristics""; ""2.2. Effect of Highly Ordered Structures""; ""2.3. Effect of Polymer Blending""; ""2.4. Effects of Material Morphology""; ""2. SURFACE PROPERTIES""; ""3. HYDROLYTIC DEGRADATION""; ""5.1. Effects of Molecular Structures""; ""5.2. Effects of Highly Ordered Structures""; ""5.3. Effects of Blending and Additives""; ""5.4. Effects of Material Morphology""; ""CONCLUSION"" ""REFERENCES""""COMPOSITES BASED ON DEGRADABLE POLYMERS""; ""ABSTRACT""; ""INTRODUCTION""; ""MATRIX MATERIALS""; ""MECHANICAL PROPERTIES OF COMPOSITES""; ""IN VITRO AND IN VIVO TESTING OF COMPOSITES""; ""MANUFACTURE OF COMPOSITES PHB/PHV BASED COMPOSITES""; ""POLYGLYCOLIC ACID (PGA) AND POLYLACTIC ACID (PLA) BASED COMPOSITES""; ""POLYCAPROLACTONE (PCL) BASED COMPOSITES""; ""PEO BASED COMPOSITES""; ""HYDROGEL BASED POLYMER COMPOSITES""; ""COMPOSITES USED FOR SCAFFOLDS""; ""IN VITRO TESTING OF DEGRADATION BEHAVIOUR""; ""IN VITRO TESTING OF BIOCOMPATIBILITY""; ""IN VIVO TESTING OF COMPOSITES"" ""CLINICAL APPLICATIONS OF DEGRADABLE COMPOSITES""""CONCLUSION""; ""REFERENCES""; ""PRODUCT REALIZATION: THE PROCESSING OF BIOABSORBABLE POLYMERS""; ""ABSTRACT""; ""THE PROCESS OF PRODUCT REALIZATION""; ""CRITICAL PERFORMANCE CRITERIA""; ""Material Physical Properties Directly Affected by ""; ""Device Delivery""; ""Healing Response""; ""Wound Environment Issues""; ""Bioabsorbable Material Availability""; ""Manufacturability""; ""RAW MATERIAL""; ""POLYMER BLENDS AND COMPOSITES""; ""QUALITY ASSURANCE PROTOCOLS""; ""MELT PROCESSING""; ""MOLDED THREAD FORMS""; ""MACHINING"" ""CONCLUSION"" |
| Record Nr. | UNINA-9910785181003321 |
Wuisman Paul I. J. M
|
||
| New York, : Nova Science Publishers, c2009 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Degradable polymers for skeletal implants [[electronic resource] /] / Paul I.J.M. Wuisman and Theo H. Smit, editors
| Degradable polymers for skeletal implants [[electronic resource] /] / Paul I.J.M. Wuisman and Theo H. Smit, editors |
| Autore | Wuisman Paul I. J. M |
| Pubbl/distr/stampa | New York, : Nova Science Publishers, c2009 |
| Descrizione fisica | 1 online resource (407 p.) |
| Disciplina | 610.28/4 |
| Altri autori (Persone) |
WuismanPaul I. J. M
SmitTheo M |
| Soggetto topico |
Polymers in medicine
Polyesters - Biocompatibility Orthopedic implants |
| ISBN | 1-61728-357-6 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
""DEGRADABLE POLYMERS FOR SKELETAL IMPLANTS""; ""DEDICATION""; ""CONTENTS""; ""PREFACE""; ""ABOUT THE EDITORS""; ""PART I: BASIC SCIENCE AND ENGINEERING""; ""THE MOLECULAR STRUCTURE OF DEGRADABLE POLYMERS""; ""ABSTRACT""; ""INTRODUCTION""; ""BIODEGRADABLE POLYMERS""; ""THE CHEMISTRY OF ESTERS""; ""THE CHEMISTRY OF POLYESTERS""; ""POLYMER TERMINOLOGY""; ""BIOCOMPATIBILITY OF BIODEGRADABLE POLYMERS""; ""POLYESTERS AS BIOMEDICAL MATERIALS""; ""1. Poly(lactic acid), PLA""; ""2. Poly(glycolic acid), PGA""; ""3. Copolymers of PGA and PLA, Poly(lactide-co-glycolide), PLGA""
""4. Bacterial Polyesters""""5. Other Polyesters""; ""6. Polyurethanes""; ""BIODEGRADATION""; ""REFERENCES""; ""TIME-DEPENDENT FAILURE IN LOAD-BEARING POLYMERS. A POTENTIAL HAZARD IN STRUCTURAL APPLICATIONS OF POLYLACTIDES""; ""ABSTRACT""; ""INTRODUCTION""; ""DELAYED FAILURE IN POLYMERS""; ""Phenomenology""; ""Origin""; ""Intrinsic Deformation Behavior""; ""Predictability of Failure""; ""Delayed Failure of Polylactides""; ""Materials""; ""Mechanical Evaluation""; ""Long-Term Performance of PLA's Vs other Glassy Polymers""; ""Influence of Molecular Degradation""; ""CONCLUDING REMARKS"" ""REFERENCES""""POLY(LACTIDE)S AND THEIR COPOLYMERS: PHYSICAL PROPERTIES AND HYDROLYTIC DEGRADATION""; ""ABSTRACT""; ""INTRODUCTION""; ""1. SYNTHESIS""; ""2. MECHANICAL PROPERTIES""; ""2.1. Effect of Molecular Characteristics""; ""2.2. Effect of Highly Ordered Structures""; ""2.3. Effect of Polymer Blending""; ""2.4. Effects of Material Morphology""; ""2. SURFACE PROPERTIES""; ""3. HYDROLYTIC DEGRADATION""; ""5.1. Effects of Molecular Structures""; ""5.2. Effects of Highly Ordered Structures""; ""5.3. Effects of Blending and Additives""; ""5.4. Effects of Material Morphology""; ""CONCLUSION"" ""REFERENCES""""COMPOSITES BASED ON DEGRADABLE POLYMERS""; ""ABSTRACT""; ""INTRODUCTION""; ""MATRIX MATERIALS""; ""MECHANICAL PROPERTIES OF COMPOSITES""; ""IN VITRO AND IN VIVO TESTING OF COMPOSITES""; ""MANUFACTURE OF COMPOSITES PHB/PHV BASED COMPOSITES""; ""POLYGLYCOLIC ACID (PGA) AND POLYLACTIC ACID (PLA) BASED COMPOSITES""; ""POLYCAPROLACTONE (PCL) BASED COMPOSITES""; ""PEO BASED COMPOSITES""; ""HYDROGEL BASED POLYMER COMPOSITES""; ""COMPOSITES USED FOR SCAFFOLDS""; ""IN VITRO TESTING OF DEGRADATION BEHAVIOUR""; ""IN VITRO TESTING OF BIOCOMPATIBILITY""; ""IN VIVO TESTING OF COMPOSITES"" ""CLINICAL APPLICATIONS OF DEGRADABLE COMPOSITES""""CONCLUSION""; ""REFERENCES""; ""PRODUCT REALIZATION: THE PROCESSING OF BIOABSORBABLE POLYMERS""; ""ABSTRACT""; ""THE PROCESS OF PRODUCT REALIZATION""; ""CRITICAL PERFORMANCE CRITERIA""; ""Material Physical Properties Directly Affected by ""; ""Device Delivery""; ""Healing Response""; ""Wound Environment Issues""; ""Bioabsorbable Material Availability""; ""Manufacturability""; ""RAW MATERIAL""; ""POLYMER BLENDS AND COMPOSITES""; ""QUALITY ASSURANCE PROTOCOLS""; ""MELT PROCESSING""; ""MOLDED THREAD FORMS""; ""MACHINING"" ""CONCLUSION"" |
| Record Nr. | UNINA-9910825713103321 |
|
Wuisman Paul I. J. M
|
||
| New York, : Nova Science Publishers, c2009 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Degradable polymers for skeletal implants [[electronic resource] /] / Paul I.J.M. Wuisman and Theo H. Smit, editors
| Degradable polymers for skeletal implants [[electronic resource] /] / Paul I.J.M. Wuisman and Theo H. Smit, editors |
| Pubbl/distr/stampa | New York, : Nova Science Publishers, c2009 |
| Descrizione fisica | 1 online resource (407 p.) |
| Disciplina | 610.28/4 |
| Altri autori (Persone) |
WuismanPaul I. J. M
SmitTheo M |
| Soggetto topico |
Polymers in medicine
Polyesters - Biocompatibility Orthopedic implants |
| Soggetto genere / forma | Electronic books. |
| ISBN | 1-61728-357-6 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
""DEGRADABLE POLYMERS FOR SKELETAL IMPLANTS""; ""DEDICATION""; ""CONTENTS""; ""PREFACE""; ""ABOUT THE EDITORS""; ""PART I: BASIC SCIENCE AND ENGINEERING""; ""THE MOLECULAR STRUCTURE OF DEGRADABLE POLYMERS""; ""ABSTRACT""; ""INTRODUCTION""; ""BIODEGRADABLE POLYMERS""; ""THE CHEMISTRY OF ESTERS""; ""THE CHEMISTRY OF POLYESTERS""; ""POLYMER TERMINOLOGY""; ""BIOCOMPATIBILITY OF BIODEGRADABLE POLYMERS""; ""POLYESTERS AS BIOMEDICAL MATERIALS""; ""1. Poly(lactic acid), PLA""; ""2. Poly(glycolic acid), PGA""; ""3. Copolymers of PGA and PLA, Poly(lactide-co-glycolide), PLGA""
""4. Bacterial Polyesters""""5. Other Polyesters""; ""6. Polyurethanes""; ""BIODEGRADATION""; ""REFERENCES""; ""TIME-DEPENDENT FAILURE IN LOAD-BEARING POLYMERS. A POTENTIAL HAZARD IN STRUCTURAL APPLICATIONS OF POLYLACTIDES""; ""ABSTRACT""; ""INTRODUCTION""; ""DELAYED FAILURE IN POLYMERS""; ""Phenomenology""; ""Origin""; ""Intrinsic Deformation Behavior""; ""Predictability of Failure""; ""Delayed Failure of Polylactides""; ""Materials""; ""Mechanical Evaluation""; ""Long-Term Performance of PLA's Vs other Glassy Polymers""; ""Influence of Molecular Degradation""; ""CONCLUDING REMARKS"" ""REFERENCES""""POLY(LACTIDE)S AND THEIR COPOLYMERS: PHYSICAL PROPERTIES AND HYDROLYTIC DEGRADATION""; ""ABSTRACT""; ""INTRODUCTION""; ""1. SYNTHESIS""; ""2. MECHANICAL PROPERTIES""; ""2.1. Effect of Molecular Characteristics""; ""2.2. Effect of Highly Ordered Structures""; ""2.3. Effect of Polymer Blending""; ""2.4. Effects of Material Morphology""; ""2. SURFACE PROPERTIES""; ""3. HYDROLYTIC DEGRADATION""; ""5.1. Effects of Molecular Structures""; ""5.2. Effects of Highly Ordered Structures""; ""5.3. Effects of Blending and Additives""; ""5.4. Effects of Material Morphology""; ""CONCLUSION"" ""REFERENCES""""COMPOSITES BASED ON DEGRADABLE POLYMERS""; ""ABSTRACT""; ""INTRODUCTION""; ""MATRIX MATERIALS""; ""MECHANICAL PROPERTIES OF COMPOSITES""; ""IN VITRO AND IN VIVO TESTING OF COMPOSITES""; ""MANUFACTURE OF COMPOSITES PHB/PHV BASED COMPOSITES""; ""POLYGLYCOLIC ACID (PGA) AND POLYLACTIC ACID (PLA) BASED COMPOSITES""; ""POLYCAPROLACTONE (PCL) BASED COMPOSITES""; ""PEO BASED COMPOSITES""; ""HYDROGEL BASED POLYMER COMPOSITES""; ""COMPOSITES USED FOR SCAFFOLDS""; ""IN VITRO TESTING OF DEGRADATION BEHAVIOUR""; ""IN VITRO TESTING OF BIOCOMPATIBILITY""; ""IN VIVO TESTING OF COMPOSITES"" ""CLINICAL APPLICATIONS OF DEGRADABLE COMPOSITES""""CONCLUSION""; ""REFERENCES""; ""PRODUCT REALIZATION: THE PROCESSING OF BIOABSORBABLE POLYMERS""; ""ABSTRACT""; ""THE PROCESS OF PRODUCT REALIZATION""; ""CRITICAL PERFORMANCE CRITERIA""; ""Material Physical Properties Directly Affected by ""; ""Device Delivery""; ""Healing Response""; ""Wound Environment Issues""; ""Bioabsorbable Material Availability""; ""Manufacturability""; ""RAW MATERIAL""; ""POLYMER BLENDS AND COMPOSITES""; ""QUALITY ASSURANCE PROTOCOLS""; ""MELT PROCESSING""; ""MOLDED THREAD FORMS""; ""MACHINING"" ""CONCLUSION"" |
| Record Nr. | UNINA-9910460008703321 |
| New York, : Nova Science Publishers, c2009 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Engineering polymer systems for improved drug delivery / / edited by Rebecca A. Bader, David A. Putnam
| Engineering polymer systems for improved drug delivery / / edited by Rebecca A. Bader, David A. Putnam |
| Pubbl/distr/stampa | Hoboken, New Jersey : , : John Wiley & Sons, , 2014 |
| Descrizione fisica | 1 online resource (492 p.) |
| Disciplina | 615.1 |
| Altri autori (Persone) |
BaderRebecca A. <1977->
PutnamDavid A. <1966-> |
| Soggetto topico |
Polymeric drug delivery systems
Polymeric drugs Polymers in medicine Drug delivery systems Drug Delivery Systems |
| ISBN |
1-118-74780-1
1-118-74789-5 1-118-74772-0 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Cover; Title Page; Copyright; CONTENTS; FOREWORD; PREFACE; CONTRIBUTORS; PART I INTRODUCTION; 1 FUNDAMENTALS OF DRUG DELIVERY; 1.1 Introduction: History and Future of Drug Delivery; 1.2 Terminology; 1.3 Basic Pharmacokinetics; 1.4 Basic Pharmacodynamics; 1.5 Mass Transfer; 1.6 Key Points; 1.7 Homework Problems; 2 CHALLENGES OF DRUG DELIVERY; 2.1 Introduction; 2.2 History and Challenges of Drug Delivery; 2.3 Physical Barriers; 2.4 Metabolic and Chemical Concerns; 2.5 Physical Properties of Therapeutics; 2.6 Polymer Carriers as a Solution to Challenges; 2.7 Key Points; 2.8 Homework Problems
PART II INJECTABLE POLYMERIC DRUG DELIVERY SYSTEMS3 POLYMER-DRUG CONJUGATES; 3.1 Introduction; 3.2 Historical Perspective; 3.3 Polymer-Drug Conjugates: Biological Rationale; 3.4 Structural Features of Polymer-Drug Conjugates; 3.5 Making a Polymer-Drug Conjugate; 3.6 Current Challenges and Future Perspectives; 3.7 Key Points; 3.8 Worked Example; 3.9 Homework Problems; 4 POLYMERIC MICROPARTICLES; 4.1 Introduction; 4.2 The Rationale for Microparticles; 4.3 Defining the Design Criteria; 4.4 Polymer Selection; 4.5 Microparticle Synthesis; 4.6 Microparticle Characterization Methods 4.7 Drug Release from Microparticles4.8 Microparticle Design Examples; 4.9 Key Points; 4.10 Worked Example; 4.11 Homework Problems; 5 POLYMERIC NANOPARTICLES; 5.1 Introduction; 5.2 PNP Design; 5.3 PNP Formulation Methods and Targeting; 5.4 Nanoparticle Targeting Overview; 5.5 PNP Characterization; 5.6 Major Clinical Achievements; 5.7 Key Points; 5.8 Worked Example; 5.9 Homework Problems; 6 BLOCK COPOLYMER MICELLES AND VESICLES FOR DRUG DELIVERY; 6.1 Introduction; 6.2 Drug Encapsulation and Release; 6.3 Bioavailability and Biodistribution; 6.4 Stimuli Responsiveness; 6.5 The Immune System 6.6 Gene Therapy6.7 Cancer Therapy; 6.8 Conclusions; 6.9 Key Points; 6.10 Homework Problems; PART III IMPLANTABLE POLYMERIC DRUG DELIVERY SYSTEMS; 7 IMPLANTABLE DRUG DELIVERY SYSTEMS; 7.1 Introduction; 7.2 Nondegradable Polymeric Implants; 7.3 Biodegradable Polymeric Implants; 7.4 Conclusions and Future Perspectives; 7.5 Key Points; 7.6 Homework Problems; 8 POLYMERIC DRUG DELIVERY SYSTEMS IN TISSUE ENGINEERING; 8.1 Introduction; 8.2 Wound Healing as a Prototype for Adult Tissue Generation; 8.3 Bioactive Factors in Tissue Engineering and Regenerative Medicine 8.4 Delivery of Growth Factors in Tissue Engineering and Regenerative Medicine8.5 Key Points; 8.6 Worked Example; 8.7 Homework Problems; PART IV ORAL POLYMERIC DRUG DELIVERY SYSTEMS; 9 ORAL CONTROLLED-RELEASE POLYMERIC DRUG DELIVERY SYSTEMS; 9.1 Introduction; 9.2 Release Mechanisms of Oral Polymeric Dosage Forms; 9.3 Oral Polymeric Release Modifiers; 9.4 Manufacturing Technologies and Industrial Applications of Controlled Release; 9.5 Worked Example; 9.6 Key Points; 9.7 Homework Problems; 10 MUCOADHESIVE DRUG DELIVERY SYSTEMS; 10.1 Introduction; 10.2 Factors Affecting Mucoadhesion 10.3 Polymer-Mucus Interactions |
| Record Nr. | UNINA-9910138963203321 |
| Hoboken, New Jersey : , : John Wiley & Sons, , 2014 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Engineering polymer systems for improved drug delivery / / edited by Rebecca A. Bader, David A. Putnam
| Engineering polymer systems for improved drug delivery / / edited by Rebecca A. Bader, David A. Putnam |
| Pubbl/distr/stampa | Hoboken, New Jersey : , : John Wiley & Sons, , 2014 |
| Descrizione fisica | 1 online resource (492 p.) |
| Disciplina | 615.1 |
| Altri autori (Persone) |
BaderRebecca A. <1977->
PutnamDavid A. <1966-> |
| Soggetto topico |
Polymeric drug delivery systems
Polymeric drugs Polymers in medicine Drug delivery systems Drug Delivery Systems |
| ISBN |
1-118-74780-1
1-118-74789-5 1-118-74772-0 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Cover; Title Page; Copyright; CONTENTS; FOREWORD; PREFACE; CONTRIBUTORS; PART I INTRODUCTION; 1 FUNDAMENTALS OF DRUG DELIVERY; 1.1 Introduction: History and Future of Drug Delivery; 1.2 Terminology; 1.3 Basic Pharmacokinetics; 1.4 Basic Pharmacodynamics; 1.5 Mass Transfer; 1.6 Key Points; 1.7 Homework Problems; 2 CHALLENGES OF DRUG DELIVERY; 2.1 Introduction; 2.2 History and Challenges of Drug Delivery; 2.3 Physical Barriers; 2.4 Metabolic and Chemical Concerns; 2.5 Physical Properties of Therapeutics; 2.6 Polymer Carriers as a Solution to Challenges; 2.7 Key Points; 2.8 Homework Problems
PART II INJECTABLE POLYMERIC DRUG DELIVERY SYSTEMS3 POLYMER-DRUG CONJUGATES; 3.1 Introduction; 3.2 Historical Perspective; 3.3 Polymer-Drug Conjugates: Biological Rationale; 3.4 Structural Features of Polymer-Drug Conjugates; 3.5 Making a Polymer-Drug Conjugate; 3.6 Current Challenges and Future Perspectives; 3.7 Key Points; 3.8 Worked Example; 3.9 Homework Problems; 4 POLYMERIC MICROPARTICLES; 4.1 Introduction; 4.2 The Rationale for Microparticles; 4.3 Defining the Design Criteria; 4.4 Polymer Selection; 4.5 Microparticle Synthesis; 4.6 Microparticle Characterization Methods 4.7 Drug Release from Microparticles4.8 Microparticle Design Examples; 4.9 Key Points; 4.10 Worked Example; 4.11 Homework Problems; 5 POLYMERIC NANOPARTICLES; 5.1 Introduction; 5.2 PNP Design; 5.3 PNP Formulation Methods and Targeting; 5.4 Nanoparticle Targeting Overview; 5.5 PNP Characterization; 5.6 Major Clinical Achievements; 5.7 Key Points; 5.8 Worked Example; 5.9 Homework Problems; 6 BLOCK COPOLYMER MICELLES AND VESICLES FOR DRUG DELIVERY; 6.1 Introduction; 6.2 Drug Encapsulation and Release; 6.3 Bioavailability and Biodistribution; 6.4 Stimuli Responsiveness; 6.5 The Immune System 6.6 Gene Therapy6.7 Cancer Therapy; 6.8 Conclusions; 6.9 Key Points; 6.10 Homework Problems; PART III IMPLANTABLE POLYMERIC DRUG DELIVERY SYSTEMS; 7 IMPLANTABLE DRUG DELIVERY SYSTEMS; 7.1 Introduction; 7.2 Nondegradable Polymeric Implants; 7.3 Biodegradable Polymeric Implants; 7.4 Conclusions and Future Perspectives; 7.5 Key Points; 7.6 Homework Problems; 8 POLYMERIC DRUG DELIVERY SYSTEMS IN TISSUE ENGINEERING; 8.1 Introduction; 8.2 Wound Healing as a Prototype for Adult Tissue Generation; 8.3 Bioactive Factors in Tissue Engineering and Regenerative Medicine 8.4 Delivery of Growth Factors in Tissue Engineering and Regenerative Medicine8.5 Key Points; 8.6 Worked Example; 8.7 Homework Problems; PART IV ORAL POLYMERIC DRUG DELIVERY SYSTEMS; 9 ORAL CONTROLLED-RELEASE POLYMERIC DRUG DELIVERY SYSTEMS; 9.1 Introduction; 9.2 Release Mechanisms of Oral Polymeric Dosage Forms; 9.3 Oral Polymeric Release Modifiers; 9.4 Manufacturing Technologies and Industrial Applications of Controlled Release; 9.5 Worked Example; 9.6 Key Points; 9.7 Homework Problems; 10 MUCOADHESIVE DRUG DELIVERY SYSTEMS; 10.1 Introduction; 10.2 Factors Affecting Mucoadhesion 10.3 Polymer-Mucus Interactions |
| Record Nr. | UNINA-9910807473803321 |
| Hoboken, New Jersey : , : John Wiley & Sons, , 2014 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Frontiers in biomaterials . Volume 1 : the design, synthetic strategies and biocompatibility of polymer scaffolds for biomedical application / / editor, Shungsheng Cao ; co-editor, Huijun Zhu
| Frontiers in biomaterials . Volume 1 : the design, synthetic strategies and biocompatibility of polymer scaffolds for biomedical application / / editor, Shungsheng Cao ; co-editor, Huijun Zhu |
| Pubbl/distr/stampa | Sharjah, U.A.E. : , : Bentham Science Publishers, Ltd., , 2014 |
| Descrizione fisica | 1 online resource (355 p.) |
| Disciplina | 610/.28 |
| Soggetto topico |
Biotechnology
Polymers in medicine Polymers |
| Soggetto genere / forma | Electronic books. |
| ISBN | 1-60805-876-X |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | COVER; Title; EUL; Contents; Foreword; Preface; LOC; CHAPTER 1; CHAPTER 2; CHAPTER 3; CHAPTER 4; CHAPTER 5; CHAPTER 6; CHAPTER 7; CHAPTER 8; CHAPTER 9; CHAPTER 10; CHAPTER 11; Index; Back |
| Record Nr. | UNINA-9910459849503321 |
| Sharjah, U.A.E. : , : Bentham Science Publishers, Ltd., , 2014 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Frontiers in biomaterials . Volume 1 : the design, synthetic strategies and biocompatibility of polymer scaffolds for biomedical application / / editor, Shungsheng Cao ; co-editor, Huijun Zhu
| Frontiers in biomaterials . Volume 1 : the design, synthetic strategies and biocompatibility of polymer scaffolds for biomedical application / / editor, Shungsheng Cao ; co-editor, Huijun Zhu |
| Pubbl/distr/stampa | Sharjah, U.A.E. : , : Bentham Science Publishers, Ltd., , 2014 |
| Descrizione fisica | 1 online resource (355 p.) |
| Disciplina | 610/.28 |
| Soggetto topico |
Biotechnology
Polymers in medicine Polymers |
| ISBN | 1-60805-876-X |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | COVER; Title; EUL; Contents; Foreword; Preface; LOC; CHAPTER 1; CHAPTER 2; CHAPTER 3; CHAPTER 4; CHAPTER 5; CHAPTER 6; CHAPTER 7; CHAPTER 8; CHAPTER 9; CHAPTER 10; CHAPTER 11; Index; Back |
| Record Nr. | UNINA-9910787132003321 |
| Sharjah, U.A.E. : , : Bentham Science Publishers, Ltd., , 2014 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Frontiers in biomaterials . Volume 1 : the design, synthetic strategies and biocompatibility of polymer scaffolds for biomedical application / / editor, Shungsheng Cao ; co-editor, Huijun Zhu
| Frontiers in biomaterials . Volume 1 : the design, synthetic strategies and biocompatibility of polymer scaffolds for biomedical application / / editor, Shungsheng Cao ; co-editor, Huijun Zhu |
| Pubbl/distr/stampa | Sharjah, U.A.E. : , : Bentham Science Publishers, Ltd., , 2014 |
| Descrizione fisica | 1 online resource (355 p.) |
| Disciplina | 610/.28 |
| Soggetto topico |
Biotechnology
Polymers in medicine Polymers |
| ISBN | 1-60805-876-X |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | COVER; Title; EUL; Contents; Foreword; Preface; LOC; CHAPTER 1; CHAPTER 2; CHAPTER 3; CHAPTER 4; CHAPTER 5; CHAPTER 6; CHAPTER 7; CHAPTER 8; CHAPTER 9; CHAPTER 10; CHAPTER 11; Index; Back |
| Record Nr. | UNINA-9910827896003321 |
| Sharjah, U.A.E. : , : Bentham Science Publishers, Ltd., , 2014 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Function-oriented bioengineered skin equivalents : continuous development towards complete skin replication / / Tanja Zidarič [and three others]
| Function-oriented bioengineered skin equivalents : continuous development towards complete skin replication / / Tanja Zidarič [and three others] |
| Autore | Zidarič Tanja |
| Pubbl/distr/stampa | Cham, Switzerland : , : Springer, , [2023] |
| Descrizione fisica | 1 online resource (170 pages) |
| Disciplina | 895.134 |
| Collana | SpringerBriefs in Molecular Science |
| Soggetto topico | Polymers in medicine |
| ISBN | 3-031-21298-3 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Intro -- Preface -- Contents -- About the Authors -- Abbreviations -- 1 Introduction -- References -- 2 Skin Physiology and Function -- References -- 3 Bioengineered Skin Substitutes -- 3.1 A Brief History -- 3.2 2D Cell Culture Models -- 3.3 3D Cell Culture Techniques -- 3.3.1 Scaffold-Free 3D Models -- 3.3.2 Conventional Scaffold-Based 3D Models -- 3.3.3 Biofabrication Approaches -- 3.3.4 Skin-On-Chip -- References -- 4 Growing Skin-Like Tissue -- 4.1 Materials -- 4.1.1 Collagen -- 4.1.2 Gelatin -- 4.1.3 Fibrin -- 4.1.4 Hyaluronic Acid -- 4.1.5 Chitosan -- 4.1.6 Alginate -- 4.1.7 Decellularized Extracellular Matrix -- 4.1.8 Synthetic Polymers -- 4.2 Cells -- 4.2.1 Keratinocytes -- 4.2.2 Fibroblasts -- 4.2.3 Stem Cells -- 4.2.4 Specialized Cell Types -- 4.3 Growth Factors -- 4.3.1 Fibroblast Growth Factor -- 4.3.2 Epidermal Growth Factor -- 4.3.3 Vascular Endothelial Growth Factor -- 4.4 Vascularization -- 4.4.1 Scaffold-Based Vascularization Strategies -- 4.4.2 Cell-Based Vascularization Strategies -- 4.4.3 Prevascularized Skin Substitutes -- 4.5 Towards "Authenticity" -- 4.5.1 Hypodermis Layer -- 4.5.2 Appendages -- 4.5.3 Skin Microbiota -- References -- 5 Commercial Skin Equivalents -- 5.1 Acellular Skin Substitutes -- 5.1.1 Alloderm® -- 5.1.2 DermaMatrix™ -- 5.1.3 Permacol® and EZ-DERM® -- 5.1.4 Oasis® -- 5.1.5 Integra® -- 5.1.6 Matriderm® -- 5.1.7 Biobrane® -- 5.1.8 Hyalomatrix® -- 5.2 Cellular Skin Substitutes -- 5.2.1 EpiCel™ -- 5.2.2 EpiSkin™ -- 5.2.3 SkinEthic™ -- 5.2.4 EpiDerm™ -- 5.2.5 Dermagraft® -- 5.2.6 TransCyte™ -- 5.2.7 Hyalograft3D™ -- 5.2.8 Apligraf® -- 5.2.9 EpiDermFT™ -- 5.2.10 StrataTest® -- References -- 6 Applications -- 6.1 Skin Reconstruction -- 6.1.1 "Bioactive" Guides for Skin Regeneration -- 6.1.2 The Regulatory Hurdles -- 6.2 Modeling of Physiological Processes -- 6.2.1 Epithelialization and Barrier Function.
6.2.2 Skin Ageing -- 6.3 Disease Modelling -- 6.3.1 Atopic Dermatitis -- 6.3.2 Psoriasis -- 6.3.3 Cutaneous Candidosis -- 6.3.4 Bacterial Infection -- 6.3.5 Skin Cancer -- 6.4 Product Testing -- 6.4.1 Percutaneous Penetration -- 6.4.2 Skin Corrosion/irritation -- 6.4.3 Genotoxicity -- References -- 7 Conclusions -- Index. |
| Record Nr. | UNINA-9910637703403321 |
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Zidarič Tanja
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| Cham, Switzerland : , : Springer, , [2023] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Handbook of polymer applications in medicine and medical devices / / edited by Kayvon Modjarrad, MD, PhD, Chief, Respiratory Disease Vaccine Development, United States National Institutes of Health, Sina Ebnesajjad, PhD, President, FluoroConsultants Group, LLC
| Handbook of polymer applications in medicine and medical devices / / edited by Kayvon Modjarrad, MD, PhD, Chief, Respiratory Disease Vaccine Development, United States National Institutes of Health, Sina Ebnesajjad, PhD, President, FluoroConsultants Group, LLC |
| Pubbl/distr/stampa | Oxford : , : William Andrew, , 2014 |
| Descrizione fisica | 1 online resource (365 p.) |
| Disciplina | 365 |
| Altri autori (Persone) |
ModjarradKayvon
EbnesajjadSina |
| Collana | PDL handbook series |
| Soggetto topico | Polymers in medicine |
| Soggetto genere / forma | Electronic books. |
| ISBN | 0-323-22169-6 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Front Cover; Handbook of Polymer Applications in Medicine and Medical Devices; Copyright Page; Contents; Preface; Author Biographies; 1 Introduction; 1.1 History; 1.2 A Historical Example; 1.3 Anthology Architecture; 1.4 Summary; References; 2 Application of Plastics in Medical Devices and Equipment; 2.1 Device Industry Overview; 2.2 Health-care Trends; 2.2.1 Minimally Invasive Surgeries; 2.2.2 Alternate Site Treatment; 2.2.3 Prevention vs. Treatment; 2.3 From Legacy Materials to Advanced Specialty Polymers for Devices; 2.4 Driving Trends Leading to New Material Requirements
2.4.1 Functionality 2.4.2 Compatibility; 2.4.3 Cost; 2.4.3.1 Material Costs or Process Improvements; 2.4.3.2 Light Weighting; 2.4.3.3 Commoditizing Materials of Construction; 2.4.3.4 Technology Innovations; 2.4.4 Ecological and Environmental Concerns and Influence of the Consumer; 2.5 Market Factors Affecting the Industry; 2.5.1 Concerns Over DEHP and Sometimes Even PVC; 2.5.2 Bisphenol A; 2.5.3 The Need for "Green"; 2.5.4 Globalization of Markets; 2.5.5 Globalization of Manufacturing; 2.5.5.1 Energy Costs; 2.5.6 Global Influences; 2.5.6.1 Infectious Diseases (MRSA, SARS, H1N1) 2.5.6.2 Economic Pressures 2.6 Conclusion; 3 Plastics Used in Medical Devices; 3.1 Plastic Compositions; 3.1.1 Polymer Properties; 3.1.1.1 Linear, Branched, and Cross-linked Polymers; 3.1.1.2 Isomers; Structural Isomers; Geometric Isomers; Stereoisomers-Syndiotactic, Isotactic, Atactic; 3.1.1.3 Molecular Weight; 3.1.2 Polymer Blends; 3.1.3 Additives; 3.1.3.1 Fillers, Reinforcement, Composites; 3.1.3.2 Release Agents; 3.1.3.3 Slip Additives/Internal Lubricants; 3.1.3.4 Catalysts; 3.1.3.5 Impact Modifiers and Tougheners; 3.1.3.6 Radiation Stabilizers; 3.1.3.7 Optical Brighteners 3.1.3.8 Plasticizers 3.1.3.9 Pigments, Extenders, Dyes, Mica; 3.1.3.10 Coupling Agents; 3.1.3.11 Thermal Stabilizers; 3.1.3.12 Antistats; 3.2 Medical Devices-Material Selection Process; 3.2.1 Physical and Mechanical Properties; 3.2.2 Thermal Properties; 3.2.3 Electrical Properties; 3.2.4 Chemical Resistance; 3.2.5 Sterilization Capability; 3.2.6 Long-Term Durability; 3.2.7 Leachables and Extractables; 3.2.8 Supplemental Tests; 3.2.9 Shelf Life and Aging; 3.2.10 Joining and Welding; 3.2.11 Medical Grade Plastics; 3.3 Common Medical Device Polymers; 3.3.1 Polyethylene; 3.3.2 Polypropylene 3.3.3 Polystyrene 3.3.4 Polyester; 3.3.5 Polyester (PLA and Other Biosorbable Plastics); 3.3.6 Polycarbonate; 3.3.7 Polyvinyl Chloride; 3.3.8 Polyethersulfone; 3.3.9 Polyacrylate (Acrylic, PMMA); 3.3.10 Hydrogel (Acrylate); 3.3.11 Polysulfone; 3.3.12 Polyetheretherketone; 3.3.13 Thermoplastic Elastomers (TPE, TPU); 3.3.14 Thermoset Elastomers-Silicone; 3.3.15 Poly-p-xylylene (Parylene); 3.3.16 Fluoropolymers; 3.4 Summary; References; 4 Polymeric Biomaterials; 4.1 Introduction; 4.2 Polymeric Biomaterials in Ophthalmology; 4.2.1 Polymeric Contact Lens; 4.2.2 Polymeric Intraocular Lens 4.2.3 Polymeric Artificial Cornea |
| Record Nr. | UNINA-9910463428503321 |
| Oxford : , : William Andrew, , 2014 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Soggetto topico
-
Polymers in medicine
(59)
- Biomedical materials (13)
- Pharmaceutical technology (8)
- Polymers (7)
- Macromolecules (6)