Info
- Utilizzare la checkbox di selezione a fianco di ciascun documento per attivare le funzionalità di stampa, invio email, download nei formati disponibili del (i) record.
Biomedical applications [[electronic resource] /] / edited by Alaa S. Abd-El-Aziz ... [et al.]
| Biomedical applications [[electronic resource] /] / edited by Alaa S. Abd-El-Aziz ... [et al.] |
| Pubbl/distr/stampa | Hoboken, NJ, : Wiley-Interscience, c2004 |
| Descrizione fisica | 1 online resource (234 p.) |
| Disciplina |
547.7
610/.28 |
| Altri autori (Persone) | Abd-El-AzizAlaa S |
| Collana | Macromolecules containing metal and metal-like elements |
| Soggetto topico |
Polymers in medicine
Macromolecules Organometallic compounds |
| Soggetto genere / forma | Electronic books. |
| ISBN |
1-280-54216-0
9786610542161 0-471-68375-2 0-471-68377-9 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Macromolecules Containing Metal and Metal-Like Elements Volume 3; Contributors; Contents; Preface; Series Preface; 1. Organometallic Compounds in Biomedical Applications; I. Introduction; II. Case for Metal-Containing Bioactive Agents; A. Tin-Containing Biocidal Polymers; B. Ferrocene: A Therapeutic Role in Polymeric Systems?; C. Polymeric Moderation of OsO(4) Toxicity; III. Miscellaneous Polymers; A. Metal Chelation Polymers; B. Condensation Polymers; IV. Small-Molecule Analogs; V. Summary; VI. References; 2. Metal-Labeled DNA on Surfaces; I. Introduction; II. Ferrocene Nucleotides
III. Ferrocene-DNA ConjugatesIV. Other Metal-DNA Conjugates; V. Metallated DNA; A. Cu-DNA; B. M-DNA; VI. Summary; VII. Acknowledgments; VIII. References; 3. Artificial DNA through Metal-Mediated Base Pairing: Structural Control and Discrete Metal Assembly; I. Introduction; II. Alternative Hydrogen-Bonding Schemes for DNA Base Pairing; III. Non-Hydrogen-Bonding Basepairs in DNA; IV. Metal-Mediated Base Pairing in DNA; A. Basic Concept; B. Artificial Nucleosides Designed for Metal-Mediated Base Pairs; C. Incorporation of a Metallo-Base Pair in DNA and Its Effect on Thermal Stability D. Discrete Self-Assembled Metal Arrays in DNAV. Future Prospects for Artificial Metallo-DNA; VI. Summary; VII. References; 4. Organotin Macromolecules as Anticancer Drugs; I. General; II. Anticancer Activity of Small Organotin Compounds; III. Molecule-Level Studies on Monomeric Organotin Compounds; IV. Anticancer Activity of Organotin Polymers; V. Future Work; VI. References; 5. Organotin Oligomeric Drugs Containing the Antivirial Agent Acyclovir; I. Early History of Organotin Compounds; II. Mechanisms and Reactions; III. General Structures; IV. Acyclovir; V. Bioactivity of Related Compounds VI. Experimental WorkVII. Results and Discussion; VIII. References; 6. Polymeric Ferrocene Conjugates as Antiproliferative Agents; I. Introduction; II. The Ferrocene-Ferricenium System in the Biological Environment; III. Polymer-Drug Conjugation as a Pharmaceutical Tool for Drug Delivery; IV. Polymer-Ferrocene Conjugates: Synthesis and Structure; A. The Carrier Component: Structural Considerations; B. Conjugates of Amide-Linked Ferrocene; C. Conjugates of Ester-Linked Ferrocene; V. Bioactivity Screening; VI. Summary and Conclusions; VII. Acknowledgments; VIII. References 7. Polymeric Platinum-Containing Drugs in the Treatment of CancerI. Introduction; II. Basic Mechanisms of Pt(II) Complex Formation; III. Nomenclature; IV. Currently Approved Platinum-Containing Compounds; V. Properties of Cisplatin; VI. Structure-Activity Relationships; VII. Polymer-Drug Conjugation Strategy and Possible Benefits; A. Polymers as Carriers; B. Polymers as Drugs; C. General; VIII. Mainchain-Incorporated cis-Diamine-Coordinated Platinum; A. Simple Amine Derivatives; B. Amino Acid Derivatives; C. Other Nitrogen-Platinum Products; D. Solution Stability; E. Thermal Stability F. Antiviral Activity |
| Record Nr. | UNINA-9910146071703321 |
| Hoboken, NJ, : Wiley-Interscience, c2004 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Biomedical applications [[electronic resource] /] / edited by Alaa S. Abd-El-Aziz ... [et al.]
| Biomedical applications [[electronic resource] /] / edited by Alaa S. Abd-El-Aziz ... [et al.] |
| Pubbl/distr/stampa | Hoboken, NJ, : Wiley-Interscience, c2004 |
| Descrizione fisica | 1 online resource (234 p.) |
| Disciplina |
547.7
610/.28 |
| Altri autori (Persone) | Abd-El-AzizAlaa S |
| Collana | Macromolecules containing metal and metal-like elements |
| Soggetto topico |
Polymers in medicine
Macromolecules Organometallic compounds |
| ISBN |
1-280-54216-0
9786610542161 0-471-68375-2 0-471-68377-9 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Macromolecules Containing Metal and Metal-Like Elements Volume 3; Contributors; Contents; Preface; Series Preface; 1. Organometallic Compounds in Biomedical Applications; I. Introduction; II. Case for Metal-Containing Bioactive Agents; A. Tin-Containing Biocidal Polymers; B. Ferrocene: A Therapeutic Role in Polymeric Systems?; C. Polymeric Moderation of OsO(4) Toxicity; III. Miscellaneous Polymers; A. Metal Chelation Polymers; B. Condensation Polymers; IV. Small-Molecule Analogs; V. Summary; VI. References; 2. Metal-Labeled DNA on Surfaces; I. Introduction; II. Ferrocene Nucleotides
III. Ferrocene-DNA ConjugatesIV. Other Metal-DNA Conjugates; V. Metallated DNA; A. Cu-DNA; B. M-DNA; VI. Summary; VII. Acknowledgments; VIII. References; 3. Artificial DNA through Metal-Mediated Base Pairing: Structural Control and Discrete Metal Assembly; I. Introduction; II. Alternative Hydrogen-Bonding Schemes for DNA Base Pairing; III. Non-Hydrogen-Bonding Basepairs in DNA; IV. Metal-Mediated Base Pairing in DNA; A. Basic Concept; B. Artificial Nucleosides Designed for Metal-Mediated Base Pairs; C. Incorporation of a Metallo-Base Pair in DNA and Its Effect on Thermal Stability D. Discrete Self-Assembled Metal Arrays in DNAV. Future Prospects for Artificial Metallo-DNA; VI. Summary; VII. References; 4. Organotin Macromolecules as Anticancer Drugs; I. General; II. Anticancer Activity of Small Organotin Compounds; III. Molecule-Level Studies on Monomeric Organotin Compounds; IV. Anticancer Activity of Organotin Polymers; V. Future Work; VI. References; 5. Organotin Oligomeric Drugs Containing the Antivirial Agent Acyclovir; I. Early History of Organotin Compounds; II. Mechanisms and Reactions; III. General Structures; IV. Acyclovir; V. Bioactivity of Related Compounds VI. Experimental WorkVII. Results and Discussion; VIII. References; 6. Polymeric Ferrocene Conjugates as Antiproliferative Agents; I. Introduction; II. The Ferrocene-Ferricenium System in the Biological Environment; III. Polymer-Drug Conjugation as a Pharmaceutical Tool for Drug Delivery; IV. Polymer-Ferrocene Conjugates: Synthesis and Structure; A. The Carrier Component: Structural Considerations; B. Conjugates of Amide-Linked Ferrocene; C. Conjugates of Ester-Linked Ferrocene; V. Bioactivity Screening; VI. Summary and Conclusions; VII. Acknowledgments; VIII. References 7. Polymeric Platinum-Containing Drugs in the Treatment of CancerI. Introduction; II. Basic Mechanisms of Pt(II) Complex Formation; III. Nomenclature; IV. Currently Approved Platinum-Containing Compounds; V. Properties of Cisplatin; VI. Structure-Activity Relationships; VII. Polymer-Drug Conjugation Strategy and Possible Benefits; A. Polymers as Carriers; B. Polymers as Drugs; C. General; VIII. Mainchain-Incorporated cis-Diamine-Coordinated Platinum; A. Simple Amine Derivatives; B. Amino Acid Derivatives; C. Other Nitrogen-Platinum Products; D. Solution Stability; E. Thermal Stability F. Antiviral Activity |
| Record Nr. | UNINA-9910830634203321 |
| Hoboken, NJ, : Wiley-Interscience, c2004 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Biomedical applications [[electronic resource] /] / edited by Alaa S. Abd-El-Aziz ... [et al.]
| Biomedical applications [[electronic resource] /] / edited by Alaa S. Abd-El-Aziz ... [et al.] |
| Pubbl/distr/stampa | Hoboken, NJ, : Wiley-Interscience, c2004 |
| Descrizione fisica | 1 online resource (234 p.) |
| Disciplina |
547.7
610/.28 |
| Altri autori (Persone) | Abd-El-AzizAlaa S |
| Collana | Macromolecules containing metal and metal-like elements |
| Soggetto topico |
Polymers in medicine
Macromolecules Organometallic compounds |
| ISBN |
1-280-54216-0
9786610542161 0-471-68375-2 0-471-68377-9 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Macromolecules Containing Metal and Metal-Like Elements Volume 3; Contributors; Contents; Preface; Series Preface; 1. Organometallic Compounds in Biomedical Applications; I. Introduction; II. Case for Metal-Containing Bioactive Agents; A. Tin-Containing Biocidal Polymers; B. Ferrocene: A Therapeutic Role in Polymeric Systems?; C. Polymeric Moderation of OsO(4) Toxicity; III. Miscellaneous Polymers; A. Metal Chelation Polymers; B. Condensation Polymers; IV. Small-Molecule Analogs; V. Summary; VI. References; 2. Metal-Labeled DNA on Surfaces; I. Introduction; II. Ferrocene Nucleotides
III. Ferrocene-DNA ConjugatesIV. Other Metal-DNA Conjugates; V. Metallated DNA; A. Cu-DNA; B. M-DNA; VI. Summary; VII. Acknowledgments; VIII. References; 3. Artificial DNA through Metal-Mediated Base Pairing: Structural Control and Discrete Metal Assembly; I. Introduction; II. Alternative Hydrogen-Bonding Schemes for DNA Base Pairing; III. Non-Hydrogen-Bonding Basepairs in DNA; IV. Metal-Mediated Base Pairing in DNA; A. Basic Concept; B. Artificial Nucleosides Designed for Metal-Mediated Base Pairs; C. Incorporation of a Metallo-Base Pair in DNA and Its Effect on Thermal Stability D. Discrete Self-Assembled Metal Arrays in DNAV. Future Prospects for Artificial Metallo-DNA; VI. Summary; VII. References; 4. Organotin Macromolecules as Anticancer Drugs; I. General; II. Anticancer Activity of Small Organotin Compounds; III. Molecule-Level Studies on Monomeric Organotin Compounds; IV. Anticancer Activity of Organotin Polymers; V. Future Work; VI. References; 5. Organotin Oligomeric Drugs Containing the Antivirial Agent Acyclovir; I. Early History of Organotin Compounds; II. Mechanisms and Reactions; III. General Structures; IV. Acyclovir; V. Bioactivity of Related Compounds VI. Experimental WorkVII. Results and Discussion; VIII. References; 6. Polymeric Ferrocene Conjugates as Antiproliferative Agents; I. Introduction; II. The Ferrocene-Ferricenium System in the Biological Environment; III. Polymer-Drug Conjugation as a Pharmaceutical Tool for Drug Delivery; IV. Polymer-Ferrocene Conjugates: Synthesis and Structure; A. The Carrier Component: Structural Considerations; B. Conjugates of Amide-Linked Ferrocene; C. Conjugates of Ester-Linked Ferrocene; V. Bioactivity Screening; VI. Summary and Conclusions; VII. Acknowledgments; VIII. References 7. Polymeric Platinum-Containing Drugs in the Treatment of CancerI. Introduction; II. Basic Mechanisms of Pt(II) Complex Formation; III. Nomenclature; IV. Currently Approved Platinum-Containing Compounds; V. Properties of Cisplatin; VI. Structure-Activity Relationships; VII. Polymer-Drug Conjugation Strategy and Possible Benefits; A. Polymers as Carriers; B. Polymers as Drugs; C. General; VIII. Mainchain-Incorporated cis-Diamine-Coordinated Platinum; A. Simple Amine Derivatives; B. Amino Acid Derivatives; C. Other Nitrogen-Platinum Products; D. Solution Stability; E. Thermal Stability F. Antiviral Activity |
| Record Nr. | UNINA-9910840948203321 |
| Hoboken, NJ, : Wiley-Interscience, c2004 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Biomedical applications of electroactive polymer actuators [[electronic resource] /] / Federico Carpi, Elisabeth Smela
| Biomedical applications of electroactive polymer actuators [[electronic resource] /] / Federico Carpi, Elisabeth Smela |
| Autore | Carpi Federico <1975-> |
| Pubbl/distr/stampa | Chichester, West Sussex ; ; Hoboken, : John Wiley & Sons, 2009 |
| Descrizione fisica | 1 online resource (506 p.) |
| Disciplina |
610.28/4
610.284 |
| Altri autori (Persone) | SmelaElisabeth |
| Soggetto topico |
Polymers in medicine
Conducting polymers Actuators |
| ISBN |
1-282-34947-3
9786612349478 0-470-74469-3 0-470-74468-5 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Biomedical Applications of Electroactive Polymer Actuators; Contents; Preface; List of Contributors; Introduction; SECTION I POLYMER GELS; 1 Polymer Gel Actuators: Fundamentals; 1.1 Introduction and Historical Overview; 1.2 Properties of Gels; 1.2.1 Biological Gels; 1.2.2 Mechanical Properties of Simple, Single-Phase Gels; 1.2.3 Elastic Moduli; 1.2.4 Strength; 1.2.5 Multi-Phase Gels; 1.2.6 Double Network Gels; 1.2.7 Transport Properties; 1.2.8 Drying; 1.3 Chemical and Physical Formation of Gels; 1.4 Actuation Methods; 1.4.1 Thermally Driven Gel Actuators
1.4.2 Chemically Driven Gel Actuators1.4.3 Gels Driven by Oscillating Reactions; 1.4.4 Light Actuated Gels; 1.4.5 Electrically Driven Gel Actuators; 1.4.6 Electro- and Magneto-Rheological Composites; 1.4.7 LC Elastomers; 1.5 Performance of Gels as Actuators; 1.6 Applications of Electroactive Gels; 1.6.1 Gel Valves and Pumps; 1.6.2 Light Modulators; 1.6.3 Gel Drug Delivery; 1.6.4 Gel Sensors; 1.7 Conclusions; References; 2 Bio-Responsive Hydrogels for Biomedical Applications; 2.1 Introduction; 2.2 Chemical Hydrogels; 2.3 Physical Hydrogels; 2.4 Defining Bio-Responsive Hydrogels 2.5 Bio-Responsive Chemical Hydrogels2.5.1 Actuation Based on Changing the Cross-Linking Density; 2.5.2 Actuation Based on Changes in Electrostatic Interactions; 2.5.3 Actuation Based on Conformational Changes; 2.6 Bio-Responsive Physical Hydrogels; 2.6.1 Enzyme-Responsive Physical Hydrogels; 2.7 Electroactive Chemical Hydrogels; 2.8 Conclusion; References; 3 Stimuli-Responsive and 'Active' Polymers in Drug Delivery; 3.1 Introduction; 3.2 Drug Delivery: Examples, Challenges and Opportunities for Polymers; 3.2.1 Oral Drug Delivery Systems; 3.2.2 Parenteral Drug Delivery 3.2.3 Topical and Transdermal Drug Delivery3.2.4 Delivery Challenges for Biomolecular Drugs and Cell Therapeutics; 3.2.5 Peptides and Proteins; 3.2.6 Nucleic Acids; 3.2.7 Cell Delivery; 3.3 Emerging State-of-the-Art Mechanisms in Polymer Controlled Release Systems; 3.3.1 Technologies for Controlled Drug Release; 3.3.2 Polymer-Drug Conjugates; 3.3.3 Polymer-Protein Conjugates; 3.3.4 Polymer-Nucleic Acid Conjugates; 3.3.5 Polymer-Nucleic Acid Complexes; 3.4 Responsive or 'Smart' Polymers in Drug Delivery; 3.4.1 Soluble Smart Polymers; 3.4.2 Responsive Polymer-Drug Conjugates 3.4.3 Responsive Polymer-Protein Conjugates3.4.4 Responsive Polymers for DNA Delivery; 3.5 Recent Highlights of Actuated Polymers for Drug Delivery Applications; 3.6 Conclusions and Future Outlook; References; 4 Thermally Driven Hydrogel Actuator for Controllable Flow Rate Pump in Long-Term Drug Delivery; 4.1 Introduction; 4.2 Materials and Methods; 4.3 Hydrogel Actuator; 4.3.1 Thermo-Mechanical Gel Dynamics; 4.3.2 Experimental Results; 4.4 Pump Functioning; 4.5 Conclusion; References; SECTION II IONIC POLYMER-METAL COMPOSITES (IPMC); 5 IPMC Actuators: Fundamentals; 5.1 Introduction 5.2 Fabrication |
| Record Nr. | UNINA-9910139963403321 |
Carpi Federico <1975->
|
||
| Chichester, West Sussex ; ; Hoboken, : John Wiley & Sons, 2009 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Biomedical applications of electroactive polymer actuators [[electronic resource] /] / Federico Carpi, Elisabeth Smela
| Biomedical applications of electroactive polymer actuators [[electronic resource] /] / Federico Carpi, Elisabeth Smela |
| Autore | Carpi Federico <1975-> |
| Pubbl/distr/stampa | Chichester, West Sussex ; ; Hoboken, : John Wiley & Sons, 2009 |
| Descrizione fisica | 1 online resource (506 p.) |
| Disciplina |
610.28/4
610.284 |
| Altri autori (Persone) | SmelaElisabeth |
| Soggetto topico |
Polymers in medicine
Conducting polymers Actuators |
| ISBN |
1-282-34947-3
9786612349478 0-470-74469-3 0-470-74468-5 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Biomedical Applications of Electroactive Polymer Actuators; Contents; Preface; List of Contributors; Introduction; SECTION I POLYMER GELS; 1 Polymer Gel Actuators: Fundamentals; 1.1 Introduction and Historical Overview; 1.2 Properties of Gels; 1.2.1 Biological Gels; 1.2.2 Mechanical Properties of Simple, Single-Phase Gels; 1.2.3 Elastic Moduli; 1.2.4 Strength; 1.2.5 Multi-Phase Gels; 1.2.6 Double Network Gels; 1.2.7 Transport Properties; 1.2.8 Drying; 1.3 Chemical and Physical Formation of Gels; 1.4 Actuation Methods; 1.4.1 Thermally Driven Gel Actuators
1.4.2 Chemically Driven Gel Actuators1.4.3 Gels Driven by Oscillating Reactions; 1.4.4 Light Actuated Gels; 1.4.5 Electrically Driven Gel Actuators; 1.4.6 Electro- and Magneto-Rheological Composites; 1.4.7 LC Elastomers; 1.5 Performance of Gels as Actuators; 1.6 Applications of Electroactive Gels; 1.6.1 Gel Valves and Pumps; 1.6.2 Light Modulators; 1.6.3 Gel Drug Delivery; 1.6.4 Gel Sensors; 1.7 Conclusions; References; 2 Bio-Responsive Hydrogels for Biomedical Applications; 2.1 Introduction; 2.2 Chemical Hydrogels; 2.3 Physical Hydrogels; 2.4 Defining Bio-Responsive Hydrogels 2.5 Bio-Responsive Chemical Hydrogels2.5.1 Actuation Based on Changing the Cross-Linking Density; 2.5.2 Actuation Based on Changes in Electrostatic Interactions; 2.5.3 Actuation Based on Conformational Changes; 2.6 Bio-Responsive Physical Hydrogels; 2.6.1 Enzyme-Responsive Physical Hydrogels; 2.7 Electroactive Chemical Hydrogels; 2.8 Conclusion; References; 3 Stimuli-Responsive and 'Active' Polymers in Drug Delivery; 3.1 Introduction; 3.2 Drug Delivery: Examples, Challenges and Opportunities for Polymers; 3.2.1 Oral Drug Delivery Systems; 3.2.2 Parenteral Drug Delivery 3.2.3 Topical and Transdermal Drug Delivery3.2.4 Delivery Challenges for Biomolecular Drugs and Cell Therapeutics; 3.2.5 Peptides and Proteins; 3.2.6 Nucleic Acids; 3.2.7 Cell Delivery; 3.3 Emerging State-of-the-Art Mechanisms in Polymer Controlled Release Systems; 3.3.1 Technologies for Controlled Drug Release; 3.3.2 Polymer-Drug Conjugates; 3.3.3 Polymer-Protein Conjugates; 3.3.4 Polymer-Nucleic Acid Conjugates; 3.3.5 Polymer-Nucleic Acid Complexes; 3.4 Responsive or 'Smart' Polymers in Drug Delivery; 3.4.1 Soluble Smart Polymers; 3.4.2 Responsive Polymer-Drug Conjugates 3.4.3 Responsive Polymer-Protein Conjugates3.4.4 Responsive Polymers for DNA Delivery; 3.5 Recent Highlights of Actuated Polymers for Drug Delivery Applications; 3.6 Conclusions and Future Outlook; References; 4 Thermally Driven Hydrogel Actuator for Controllable Flow Rate Pump in Long-Term Drug Delivery; 4.1 Introduction; 4.2 Materials and Methods; 4.3 Hydrogel Actuator; 4.3.1 Thermo-Mechanical Gel Dynamics; 4.3.2 Experimental Results; 4.4 Pump Functioning; 4.5 Conclusion; References; SECTION II IONIC POLYMER-METAL COMPOSITES (IPMC); 5 IPMC Actuators: Fundamentals; 5.1 Introduction 5.2 Fabrication |
| Record Nr. | UNINA-9910830315503321 |
|
Carpi Federico <1975->
|
||
| Chichester, West Sussex ; ; Hoboken, : John Wiley & Sons, 2009 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Biomedical applications of electroactive polymer actuators [[electronic resource] /] / Federico Carpi, Elisabeth Smela
| Biomedical applications of electroactive polymer actuators [[electronic resource] /] / Federico Carpi, Elisabeth Smela |
| Autore | Carpi Federico <1975-> |
| Pubbl/distr/stampa | Chichester, West Sussex ; ; Hoboken, : John Wiley & Sons, 2009 |
| Descrizione fisica | 1 online resource (506 p.) |
| Disciplina |
610.28/4
610.284 |
| Altri autori (Persone) | SmelaElisabeth |
| Soggetto topico |
Polymers in medicine
Conducting polymers Actuators |
| ISBN |
1-282-34947-3
9786612349478 0-470-74469-3 0-470-74468-5 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Biomedical Applications of Electroactive Polymer Actuators; Contents; Preface; List of Contributors; Introduction; SECTION I POLYMER GELS; 1 Polymer Gel Actuators: Fundamentals; 1.1 Introduction and Historical Overview; 1.2 Properties of Gels; 1.2.1 Biological Gels; 1.2.2 Mechanical Properties of Simple, Single-Phase Gels; 1.2.3 Elastic Moduli; 1.2.4 Strength; 1.2.5 Multi-Phase Gels; 1.2.6 Double Network Gels; 1.2.7 Transport Properties; 1.2.8 Drying; 1.3 Chemical and Physical Formation of Gels; 1.4 Actuation Methods; 1.4.1 Thermally Driven Gel Actuators
1.4.2 Chemically Driven Gel Actuators1.4.3 Gels Driven by Oscillating Reactions; 1.4.4 Light Actuated Gels; 1.4.5 Electrically Driven Gel Actuators; 1.4.6 Electro- and Magneto-Rheological Composites; 1.4.7 LC Elastomers; 1.5 Performance of Gels as Actuators; 1.6 Applications of Electroactive Gels; 1.6.1 Gel Valves and Pumps; 1.6.2 Light Modulators; 1.6.3 Gel Drug Delivery; 1.6.4 Gel Sensors; 1.7 Conclusions; References; 2 Bio-Responsive Hydrogels for Biomedical Applications; 2.1 Introduction; 2.2 Chemical Hydrogels; 2.3 Physical Hydrogels; 2.4 Defining Bio-Responsive Hydrogels 2.5 Bio-Responsive Chemical Hydrogels2.5.1 Actuation Based on Changing the Cross-Linking Density; 2.5.2 Actuation Based on Changes in Electrostatic Interactions; 2.5.3 Actuation Based on Conformational Changes; 2.6 Bio-Responsive Physical Hydrogels; 2.6.1 Enzyme-Responsive Physical Hydrogels; 2.7 Electroactive Chemical Hydrogels; 2.8 Conclusion; References; 3 Stimuli-Responsive and 'Active' Polymers in Drug Delivery; 3.1 Introduction; 3.2 Drug Delivery: Examples, Challenges and Opportunities for Polymers; 3.2.1 Oral Drug Delivery Systems; 3.2.2 Parenteral Drug Delivery 3.2.3 Topical and Transdermal Drug Delivery3.2.4 Delivery Challenges for Biomolecular Drugs and Cell Therapeutics; 3.2.5 Peptides and Proteins; 3.2.6 Nucleic Acids; 3.2.7 Cell Delivery; 3.3 Emerging State-of-the-Art Mechanisms in Polymer Controlled Release Systems; 3.3.1 Technologies for Controlled Drug Release; 3.3.2 Polymer-Drug Conjugates; 3.3.3 Polymer-Protein Conjugates; 3.3.4 Polymer-Nucleic Acid Conjugates; 3.3.5 Polymer-Nucleic Acid Complexes; 3.4 Responsive or 'Smart' Polymers in Drug Delivery; 3.4.1 Soluble Smart Polymers; 3.4.2 Responsive Polymer-Drug Conjugates 3.4.3 Responsive Polymer-Protein Conjugates3.4.4 Responsive Polymers for DNA Delivery; 3.5 Recent Highlights of Actuated Polymers for Drug Delivery Applications; 3.6 Conclusions and Future Outlook; References; 4 Thermally Driven Hydrogel Actuator for Controllable Flow Rate Pump in Long-Term Drug Delivery; 4.1 Introduction; 4.2 Materials and Methods; 4.3 Hydrogel Actuator; 4.3.1 Thermo-Mechanical Gel Dynamics; 4.3.2 Experimental Results; 4.4 Pump Functioning; 4.5 Conclusion; References; SECTION II IONIC POLYMER-METAL COMPOSITES (IPMC); 5 IPMC Actuators: Fundamentals; 5.1 Introduction 5.2 Fabrication |
| Record Nr. | UNINA-9910840796903321 |
|
Carpi Federico <1975->
|
||
| Chichester, West Sussex ; ; Hoboken, : John Wiley & Sons, 2009 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Biomedical applications of polymeric materials and composites / / edited by Raju Francis and D. Sakthi Kumar
| Biomedical applications of polymeric materials and composites / / edited by Raju Francis and D. Sakthi Kumar |
| Pubbl/distr/stampa | Weinheim : , : Wiley-VCH, , [2017] |
| Descrizione fisica | 1 online resource (415 p.) |
| Soggetto topico |
Polymers in medicine
Biomedical materials Biopolymers |
| ISBN |
3-527-69092-1
3-527-69094-8 3-527-69091-3 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Cover; Title Page; Copyright; Contents; List of Contributors; Preface; Chapter 1 Biomaterials for Biomedical Applications; 1.1 Introduction; 1.2 Polymers as Hydrogels in Cell Encapsulation and Soft Tissue Replacement; 1.3 Biomaterials for Drug Delivery Systems; 1.4 Biomaterials for Heart Valves and Arteries; 1.5 Biomaterials for Bone Repair; 1.6 Conclusion; Abbreviations; References; Chapter 2 Conducting Polymers: An Introduction; 2.1 Introduction; 2.2 Types of Conducting Polymers; 2.2.1 Poly(thiophene); 2.2.2 Poly(para-phenylenevinylene); 2.2.3 Poly(carbazole); 2.2.4 Polyaniline
2.2.5 Polypyrrole2.3 Synthesis of Conducting Polymers; 2.4 Surface Functionalization of Conducting Polymers; 2.4.1 Physical-Chemical Modifications; 2.4.2 Electrical Property Modification; 2.4.3 Mechanical Property Modification; Abbreviations; References; Chapter 3 Conducting Polymers: Biomedical Applications; 3.1 Applications; 3.1.1 Drug Delivery; 3.1.1.1 Release and Diffusion; 3.1.1.2 Targeting and Delivery; 3.1.2 Electrode Coating; 3.1.3 Biological Sensors; 3.1.4 Bioactuators; 3.1.5 Tissue Engineering Applications; 3.1.5.1 Neural Applications; 3.1.5.2 Cardiovascular Applications 3.1.5.3 Applications in Brain Recording3.1.5.4 Applications in Scaffolds; 3.2 Conclusions; Abbreviations; References; Chapter 4 Plasma-Assisted Fabrication and Processing of Biomaterials; 4.1 Introduction; 4.1.1 Plasma in Medicine; 4.1.2 Plasma Sterilization; 4.1.3 Plasma Treatment of Cells; 4.1.4 Plasma-Assisted Surface Modification; 4.1.5 Plasma Functionalization; 4.1.6 Plasma-Enabled Synthesis of Polymers; 4.1.7 Plasma-Enhanced Fabrication of Amorphous and Graphene-Like Carbon; 4.1.7.1 Plasma Polymerized Diamond-Like Carbon (DLC) Films; 4.1.7.2 DLC films as Hemocompatible Coatings 4.1.7.3 DLC Films as Antibacterial Coatings4.1.7.4 DLC Films as Corrosion Resistant and Low Wear Coatings; 4.1.7.5 Efficacy of DLC Films Tested in vivo; 4.1.7.6 Plasma-Enhanced Synthesis of Graphene and Carbon Nanoparticles; 4.2 Conclusion; References; Chapter 5 Smart Electroactive Polymers and Composite Materials; 5.1 Introduction; 5.2 Types of Electroactive Polymers; 5.3 Polymer Gels; 5.4 Conducting Polymers; 5.5 Ionic Polymer-Metal Composites (IPMC); 5.6 Conjugated Polymer; 5.7 Piezoelectric and Electrostrictive Polymers; 5.8 Dielectric Elastomers; 5.9 Summary; References Chapter 6 Synthetic Polymer Hydrogels6.1 Introduction; 6.2 Polymer Hydrogels; 6.3 Synthetic Polymer Hydrogels; 6.3.1 Methods to Synthesis Hydrogels; 6.3.1.1 Physical Cross-Linking; 6.3.1.2 Chemical Cross-Linking; 6.3.1.3 Radiation Cross-Linking; 6.3.2 Examples of Synthetic Polymer Hydrogels; 6.3.2.1 Poly(acrylic acid) and its Derivatives; 6.3.2.2 Poly(ethylene oxide) (PEO) and its Copolymers; 6.3.2.3 Poly(vinyl pyrrolidone) (PVP); 6.3.2.4 Poly(vinyl alcohol) (PVA) Hydrogel; 6.3.2.5 Polypeptide Hydrogels; 6.3.3 Properties of Synthetic Polymer Hydrogels; 6.3.3.1 Smart Polymer Hydrogels 6.3.3.2 Swelling Property |
| Record Nr. | UNINA-9910134854903321 |
| Weinheim : , : Wiley-VCH, , [2017] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Biomedical applications of polymeric materials and composites / / edited by Raju Francis and D. Sakthi Kumar
| Biomedical applications of polymeric materials and composites / / edited by Raju Francis and D. Sakthi Kumar |
| Pubbl/distr/stampa | Weinheim : , : Wiley-VCH, , [2017] |
| Descrizione fisica | 1 online resource (415 p.) |
| Soggetto topico |
Polymers in medicine
Biomedical materials Biopolymers |
| ISBN |
3-527-69092-1
3-527-69094-8 3-527-69091-3 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Cover; Title Page; Copyright; Contents; List of Contributors; Preface; Chapter 1 Biomaterials for Biomedical Applications; 1.1 Introduction; 1.2 Polymers as Hydrogels in Cell Encapsulation and Soft Tissue Replacement; 1.3 Biomaterials for Drug Delivery Systems; 1.4 Biomaterials for Heart Valves and Arteries; 1.5 Biomaterials for Bone Repair; 1.6 Conclusion; Abbreviations; References; Chapter 2 Conducting Polymers: An Introduction; 2.1 Introduction; 2.2 Types of Conducting Polymers; 2.2.1 Poly(thiophene); 2.2.2 Poly(para-phenylenevinylene); 2.2.3 Poly(carbazole); 2.2.4 Polyaniline
2.2.5 Polypyrrole2.3 Synthesis of Conducting Polymers; 2.4 Surface Functionalization of Conducting Polymers; 2.4.1 Physical-Chemical Modifications; 2.4.2 Electrical Property Modification; 2.4.3 Mechanical Property Modification; Abbreviations; References; Chapter 3 Conducting Polymers: Biomedical Applications; 3.1 Applications; 3.1.1 Drug Delivery; 3.1.1.1 Release and Diffusion; 3.1.1.2 Targeting and Delivery; 3.1.2 Electrode Coating; 3.1.3 Biological Sensors; 3.1.4 Bioactuators; 3.1.5 Tissue Engineering Applications; 3.1.5.1 Neural Applications; 3.1.5.2 Cardiovascular Applications 3.1.5.3 Applications in Brain Recording3.1.5.4 Applications in Scaffolds; 3.2 Conclusions; Abbreviations; References; Chapter 4 Plasma-Assisted Fabrication and Processing of Biomaterials; 4.1 Introduction; 4.1.1 Plasma in Medicine; 4.1.2 Plasma Sterilization; 4.1.3 Plasma Treatment of Cells; 4.1.4 Plasma-Assisted Surface Modification; 4.1.5 Plasma Functionalization; 4.1.6 Plasma-Enabled Synthesis of Polymers; 4.1.7 Plasma-Enhanced Fabrication of Amorphous and Graphene-Like Carbon; 4.1.7.1 Plasma Polymerized Diamond-Like Carbon (DLC) Films; 4.1.7.2 DLC films as Hemocompatible Coatings 4.1.7.3 DLC Films as Antibacterial Coatings4.1.7.4 DLC Films as Corrosion Resistant and Low Wear Coatings; 4.1.7.5 Efficacy of DLC Films Tested in vivo; 4.1.7.6 Plasma-Enhanced Synthesis of Graphene and Carbon Nanoparticles; 4.2 Conclusion; References; Chapter 5 Smart Electroactive Polymers and Composite Materials; 5.1 Introduction; 5.2 Types of Electroactive Polymers; 5.3 Polymer Gels; 5.4 Conducting Polymers; 5.5 Ionic Polymer-Metal Composites (IPMC); 5.6 Conjugated Polymer; 5.7 Piezoelectric and Electrostrictive Polymers; 5.8 Dielectric Elastomers; 5.9 Summary; References Chapter 6 Synthetic Polymer Hydrogels6.1 Introduction; 6.2 Polymer Hydrogels; 6.3 Synthetic Polymer Hydrogels; 6.3.1 Methods to Synthesis Hydrogels; 6.3.1.1 Physical Cross-Linking; 6.3.1.2 Chemical Cross-Linking; 6.3.1.3 Radiation Cross-Linking; 6.3.2 Examples of Synthetic Polymer Hydrogels; 6.3.2.1 Poly(acrylic acid) and its Derivatives; 6.3.2.2 Poly(ethylene oxide) (PEO) and its Copolymers; 6.3.2.3 Poly(vinyl pyrrolidone) (PVP); 6.3.2.4 Poly(vinyl alcohol) (PVA) Hydrogel; 6.3.2.5 Polypeptide Hydrogels; 6.3.3 Properties of Synthetic Polymer Hydrogels; 6.3.3.1 Smart Polymer Hydrogels 6.3.3.2 Swelling Property |
| Record Nr. | UNINA-9910814773303321 |
| Weinheim : , : Wiley-VCH, , [2017] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Biosynthetic polymers for medical applications / / edited by L Poole-Warren, P. Martens and R. Green
| Biosynthetic polymers for medical applications / / edited by L Poole-Warren, P. Martens and R. Green |
| Pubbl/distr/stampa | Waltham, MA : , : Elsevier, , [2016] |
| Descrizione fisica | 1 online resource (360 p.) |
| Collana | Woodhead Publishing series in biomaterials |
| Soggetto topico |
Polymers in medicine
Polymers Biosynthesis Polymerization |
| ISBN | 1-78242-113-0 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Front Cover; Related titles; Biosynthetic Polymers for Medical Applications; Copyright; Contents; List of contributors; Woodhead Publishing Series in Biomaterials; Part One - Introduction and fundamentals; 1 - Introduction to biomedical polymers and biocompatibility; 1.1 Introduction; 1.2 Natural or biological polymers; 1.2.1 Extracellular matrix; 1.2.2 Isolation and processing of natural polymers; 1.2.3 Protein polymers; 1.2.4 Carbohydrate-based polymers; 1.3 Advantages and disadvantages of natural polymers; 1.3.1 Biological polymer benefits; 1.3.2 Limitations of natural polymers
1.4 Biosynthetic polymers1.5 Conclusion; References; 2 - Nondegradable synthetic polymers for medical devices and implants; 2.1 Introduction; 2.1.1 Introduction to various classes of synthetic polymers; 2.2 Ultra-high molecular weight poly(ethylene) (UHMWPE); 2.2.1 Biomedical applications of UHMWPE; 2.2.2 Biocompatibility and stability of UHMWPE; 2.3 Polypropylene (PP); 2.3.1 Biomedical applications of PP; 2.4 Poly(methyl methacrylate) (PMMA); 2.4.1 Biomedical applications of PMMA; 2.4.2 Biocompatibility and stability of PMMA; 2.5 Polyurethane (PU); 2.5.1 Synthesis and properties of PU 2.5.2 Biostability and applications of PU2.6 Poly(dimethyl siloxane) (PDMS); 2.6.1 Chemistry and synthesis of PDMS; 2.6.2 Biomedical applications of PDMS; 2.6.3 Biocompatibility and stability of PDMS; 2.7 Polyether ether ketone (PEEK); 2.7.1 Synthesis and properties of PEEK; 2.7.2 Biocompatibility and implant applications of PEEK; 2.8 Future directions; References; 3 - Biodegradable and bioerodible polymers for medical applications; 3.1 Introduction; 3.2 Concepts and terminology; 3.2.1 Biodegradable and bioerodible; 3.2.2 Natural and synthetic polymers; 3.2.3 Controlled release 3.2.3.1 Temporal control3.2.3.2 Distribution control; 3.2.4 Polymer-drug conjugates; 3.2.5 Polymeric delivery systems; 3.2.5.1 Hydrogels; 3.2.5.2 Self-assembled systems; 3.2.5.3 Complexes; 3.3 Motivating factors for using polymer-drug conjugates; 3.3.1 Passive accumulation: drug targeting via the EPR effect; 3.3.2 Site-specific drug release; 3.3.3 Improved stabilisation; 3.3.4 Multivalent interactions; 3.4 Current and future trends; 3.4.1 Bioactive polymers; 3.4.2 Polymers that degrade into bioactives; Acknowledgments; References; Part Two - Coatings and surface modifications 4 - Bio-inspired antimicrobial polymers4.1 Introduction; 4.2 Naturally occurring AMPs; 4.3 Synthetic polymer mimics of AMPs; 4.3.1 Generation of amphiphilicity; 4.3.1.1 Single pendants: the use of monomers bearing a single hydrophobic or cationic pendant group; 4.3.1.2 Dual pendants: the use of monomers that contain both hydrophilic and cationic pendant groups connected to the same centre; 4.3.1.3 Serial pendants: the use of monomers that contain both hydrophilic and cationic groups joined in series within one monomer unit; 4.3.2 Polymerisation methods; 4.3.3 Cationic to hydrophobic balance 4.3.4 Source and location of charge |
| Record Nr. | UNISA-996426335303316 |
| Waltham, MA : , : Elsevier, , [2016] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. di Salerno | ||
| ||
Chitosan-based systems for biopharmaceuticals [[electronic resource] ] : delivery, targeting, and polymer therapeutics / / edited by Bruno Sarmento, José das Neves
| Chitosan-based systems for biopharmaceuticals [[electronic resource] ] : delivery, targeting, and polymer therapeutics / / edited by Bruno Sarmento, José das Neves |
| Edizione | [2nd ed.] |
| Pubbl/distr/stampa | Chichester, West Sussex, : John Wiley & Sons, 2012 |
| Descrizione fisica | xxvi, 556 p. : ill |
| Disciplina | 615.1/9 |
| Altri autori (Persone) |
SarmentoBruno
NevesJosé das <1978-> |
| Soggetto topico |
Chitosan - Therapeutic use
Polymers in medicine |
| ISBN |
1-119-96297-8
1-280-59176-5 9786613621597 1-119-96296-X 1-119-96407-5 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Chemical and technological advances in chitins and chitosans useful for the formulation of biopharmaceuticals / Riccardo A.A. Muzzarelli -- Physical properties of chitosan and derivatives in sol and gel states / Marguerite Rinaudo -- Absorption promotion properties of chitosan and derivatives / Akira Yamamoto -- Biocompatibility and biodegradation of chitosan and derivatives / Ahmad Sukari Halim [and others] -- Biological and pharmacological activity of chitosan and derivatives / Teresa Cunha [and others] -- Biological, chemical, and physical compatibility of chitosan and biopharmaceuticals / Masayuki Ishihara [and others] -- Approaches for functional modification or crosslinking of chitosan / A. Anitha [and others] -- Use of chitosan and derivatives in conventional biopharmaceutical dosage forms formulation / Teófilo Vasconcelos, Pedro Barrocas, Rui Cerdeira -- Manufacture techniques of chitosan-based microparticles and nanoparticles for biopharmaceuticals / Franca Ferrari [and others] -- Chitosan and derivatives for biopharmaceutical use : mucoadhesive properties / Katharina Leithner, Andreas Bernkop-Schnürch -- Chitosan-based systems for mucosal delivery of biopharmaceuticals / Sonia Al-Qadi, Ana Grenha, Carmen Remuñán-López -- Chitosan-based delivery systems for mucosal vaccination / Gerrit Borchard, Farnaz Esmaeili, Simon Heuking -- Chitosan-based nanoparticulates for oral delivery of biopharmaceuticals / Filipa Antunes, Fernanda Andrade, Bruno Sarmento.
Chitosan-based systems for ocular delivery of biopharmaceuticals / Suresh P. Vyas, Rishi Paliwal, Shivani Rai Paliwal -- Chemical modification of chitosan for delivery of DNA and siRNA / You-Kyoung Kim [and others] -- Target-specific chitosan-based nanoparticle systems for nucleic acid delivery / Shardool Jain, Mansoor Amiji -- Functional PEGylated chitosan systems for biopharmaceuticals / Hee-Jeong Cho [and others] -- Stimuli-sensitive chitosan-based systems for biopharmaceuticals / Cuiping Zhai, Jinfang Yuan, Qingyu Gao -- Chitosan copolymers for biopharmaceuticals / Ramon Novoa-Carballal, Ricardo Riguera, Eduardo Fernandez-Megia -- Application of chitosan for anti-cancer biopharmaceutical delivery / Claudia Philippi [and others] -- Chitosan-based biopharmaceuticals scaffolds in tissue engineering and regenerative medicine / Tao Jiang [and others] -- Wound healing properties of chitosan and its use in wound dressing biopharmaceuticals / Tyler G. St. Denis [and others] -- Toxicological properties of chitosan and derivatives for biopharmaceutical applications / Thomas J. Kean, Maya Thanou -- Regulatory status of chitosan and derivatives / Michael Dornish, David S. Kaplan, Sambasiva R. Arepalli -- Patentability and intellectual property issues related with chitosan-based biopharmaceutical products / Mafalda Videira, Rogrio Gaspar -- Quality control and good manufacturing practice (GMP) for chitosan-based biopharmaceutical products / Torsten Richter, Maika Gulich, Katja Richter -- Preclinical and clinical use of chitosan and derivatives for biopharmaceuticals : from preclinical research to the bedside / David A. Zaharoff [and others]. |
| Record Nr. | UNINA-9910208840303321 |
| Chichester, West Sussex, : John Wiley & Sons, 2012 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Soggetto topico
-
Polymers in medicine
(59)
- Biomedical materials (13)
- Pharmaceutical technology (8)
- Polymers (7)
- Macromolecules (6)