Genome-based therapeutics : targeted drug discovery and development : workshop summary / / Adam C. Berger and Steve Olson, Rapporteurs ; Roundtable on Translating Genomic-Based Research for Health, Board on Health Sciences Policy, Institute of Medicine of the National Academies |
Pubbl/distr/stampa | Washington, District of Columbia : , : National Academies Press, , [2012] |
Descrizione fisica | 1 online resource (109 p.) |
Disciplina | 615.1 |
Soggetto topico |
Drugs - United States - Design
Pharmaceutical technology - United States Pharmaceutical industry - United States Genomics - United States |
ISBN |
0-309-26027-2
0-309-26025-6 |
Formato | Materiale a stampa ![]() |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto | Introduction -- The current landscape -- Case studies: The development of Crizotinib for treatment of non-small-cell lung cancer; Use of genetics to inform drug development for the treatment of schizophrenia; A genetic approach to the treatment of cystic fibrosis -- Emerging technologies in drug development: Large-scale whole-genome sequencing; The value of clinical next-generation sequencing to drug developers; The uses of genomic information -- Evolving paradigms: Foundations and drug development: an example; Genomics and regulatory science; Pharmacy benefit management and pharmacogenomics; Repurposing of drugs -- Forging collaborative strategies for the development of personalized medicine: The need for collaboration; FDA initiatives; NCATS initiatives; Biospecimens and databases; Reducing health disparities; Patient and physican education; An emphasis on the science. |
Record Nr. | UNINA-9910787308203321 |
Washington, District of Columbia : , : National Academies Press, , [2012] | ||
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Lo trovi qui: Univ. Federico II | ||
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Genome-based therapeutics : targeted drug discovery and development : workshop summary / / Adam C. Berger and Steve Olson, Rapporteurs ; Roundtable on Translating Genomic-Based Research for Health, Board on Health Sciences Policy, Institute of Medicine of the National Academies |
Pubbl/distr/stampa | Washington, District of Columbia : , : National Academies Press, , [2012] |
Descrizione fisica | 1 online resource (109 p.) |
Disciplina | 615.1 |
Soggetto topico |
Drugs - United States - Design
Pharmaceutical technology - United States Pharmaceutical industry - United States Genomics - United States |
ISBN |
0-309-26027-2
0-309-26025-6 |
Formato | Materiale a stampa ![]() |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto | Introduction -- The current landscape -- Case studies: The development of Crizotinib for treatment of non-small-cell lung cancer; Use of genetics to inform drug development for the treatment of schizophrenia; A genetic approach to the treatment of cystic fibrosis -- Emerging technologies in drug development: Large-scale whole-genome sequencing; The value of clinical next-generation sequencing to drug developers; The uses of genomic information -- Evolving paradigms: Foundations and drug development: an example; Genomics and regulatory science; Pharmacy benefit management and pharmacogenomics; Repurposing of drugs -- Forging collaborative strategies for the development of personalized medicine: The need for collaboration; FDA initiatives; NCATS initiatives; Biospecimens and databases; Reducing health disparities; Patient and physican education; An emphasis on the science. |
Record Nr. | UNINA-9910824065303321 |
Washington, District of Columbia : , : National Academies Press, , [2012] | ||
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Lo trovi qui: Univ. Federico II | ||
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Improving drug pricing transparency and lowering prices for American consumers : hearing before the Subcommittee on Health of the Committee on Energy and Commerce, House of Representatives, One Hundred Sixteenth Congress, first session, May 21, 2019 |
Pubbl/distr/stampa | Washington : , : U.S. Government Publishing Office, , 2021 |
Descrizione fisica | 1 online resource (vi, 187 pages) : color illustrations |
Soggetto topico |
Drugs - Prices - United States
Pharmaceutical industry - United States Prescription pricing - United States Prescription pricing - Law and legislation - United States Insurance premiums - Law and legislation - United States |
Soggetto genere / forma | Legislative hearings. |
Formato | Materiale a stampa ![]() |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Altri titoli varianti | Improving drug pricing transparency and lowering prices for American consumers |
Record Nr. | UNINA-9910716543703321 |
Washington : , : U.S. Government Publishing Office, , 2021 | ||
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Lo trovi qui: Univ. Federico II | ||
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Journal of research in pharmaceutical economics |
Pubbl/distr/stampa | [Binghamton, NY], : Haworth Press, [©1989]-©2001 |
Descrizione fisica | 1 online resource |
Disciplina | 338.4/76151/097305 |
Soggetto topico |
Pharmaceutical industry - United States
Pharmaceutical industry Drug Industry - economics |
Soggetto genere / forma |
Periodicals
Periodicals. |
Formato | Materiale a stampa ![]() |
Livello bibliografico | Periodico |
Lingua di pubblicazione | eng |
Altri titoli varianti | Pharmaceutical economics |
Record Nr. | UNINA-9910219649703321 |
[Binghamton, NY], : Haworth Press, [©1989]-©2001 | ||
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Lo trovi qui: Univ. Federico II | ||
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Legislative proposal to increase funding for medical research : hearing before a subcommittee of the Committee on Appropriations, United States Senate, One Hundred Fifth Congress, first session, special hearing |
Pubbl/distr/stampa | Washington : , : U.S. Government Printing Office, , 1998 |
Descrizione fisica | 1 online resource (iii, 35, pages) |
Collana | S. hrg. |
Soggetto topico |
Drugs - Research - United States - Finance
Medicine - Research - United States Pharmaceutical industry - United States Pharmaceutical policy - United States Science and state - United States |
Soggetto genere / forma | Legislative hearings. |
Formato | Materiale a stampa ![]() |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Record Nr. | UNINA-9910714005503321 |
Washington : , : U.S. Government Printing Office, , 1998 | ||
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Lo trovi qui: Univ. Federico II | ||
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Lowering the cost of prescription drugs : reducing barriers to market competition : hearing before the Subcommittee on Health of the Committee on Energy and Commerce, House of Representatives, One Hundred Sixteenth Congress, first session, March 13, 2019 |
Pubbl/distr/stampa | Washington : , : U.S. Government Publishing Office, , 2021 |
Descrizione fisica | 1 online resource (vi, 246 pages) |
Soggetto topico |
Prescription pricing - United States - Public opinion
Drugs - Generic substitution - Law and legislation - United States Drugs - Law and legislation - United States Drugs - United States - Patents Patent laws and legislation - United States Competition - United States Pharmaceutical industry - United States |
Soggetto genere / forma | Legislative hearings. |
Formato | Materiale a stampa ![]() |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Altri titoli varianti | Lowering the cost of prescription drugs |
Record Nr. | UNINA-9910715471103321 |
Washington : , : U.S. Government Publishing Office, , 2021 | ||
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Lo trovi qui: Univ. Federico II | ||
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Making health care more affordable : lowering drug prices and increasing transparency : hearing before the Subcommittee on Health, Employment, Labor and Pensions, Committee on Education and Labor, U.S. House of Representatives, One Hundred Sixteenth Congress, first session : hearing held in Washington, DC, September 26, 2019 |
Pubbl/distr/stampa | Washington : , : U.S. Government Publishing Office, , 2021 |
Descrizione fisica | 1 online resource (iv, 175 pages) : color illustrations |
Soggetto topico |
Prescription pricing - United States
Drugs - Prices - United States Pharmaceutical industry - United States Social responsibility of business - United States Drugs - Prices Pharmaceutical industry Prescription pricing Social responsibility of business |
Soggetto genere / forma | Legislative hearings. |
Formato | Materiale a stampa ![]() |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Altri titoli varianti | Making health care more affordable |
Record Nr. | UNINA-9910715252803321 |
Washington : , : U.S. Government Publishing Office, , 2021 | ||
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Lo trovi qui: Univ. Federico II | ||
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Manufacturer safeguards may not prevent copayment coupon use for Part D drugs |
Pubbl/distr/stampa | Washington, DC : , : Department of Health and Human Services, Office of Inspector General, , 2014 |
Descrizione fisica | 1 online resource (29 pages) : color illustrations |
Soggetto topico |
Medicare - Claims administration
Pharmaceutical industry - United States Nonprescription drug industry - United States Copayments (Insurance) - Law and legislation - United States Drugs - Prices - United States |
Formato | Materiale a stampa ![]() |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Altri titoli varianti | Manufacturer safeguards may not prevent copayment coupon use for Part D drugs |
Record Nr. | UNINA-9910707259203321 |
Washington, DC : , : Department of Health and Human Services, Office of Inspector General, , 2014 | ||
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Lo trovi qui: Univ. Federico II | ||
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National Centers of Excellence in Continuous Pharmaceutical Manufacturing Act of 2020 : report (to accompany H.R. 4866) |
Pubbl/distr/stampa | [Washington, D.C.] : , : [U.S. Government Publishing Office], , [2020] |
Descrizione fisica | 1 online resource (16 pages) |
Disciplina | 1.1/8:116-513 |
Collana | Report / 116th Congress, 2d session, House of Representatives |
Soggetto topico |
Pharmaceutical technology - United States
Pharmaceutical industry - United States Pharmaceutical industry Pharmaceutical technology |
Soggetto genere / forma | Legislative materials. |
Formato | Materiale a stampa ![]() |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Altri titoli varianti | National Centers of Excellence in Continuous Pharmaceutical Manufacturing Act of 2020 |
Record Nr. | UNINA-9910715152703321 |
[Washington, D.C.] : , : [U.S. Government Publishing Office], , [2020] | ||
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Lo trovi qui: Univ. Federico II | ||
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Nutraceuticals : efficacy, safety and toxicity / / edited by Ramesh C. Gupta |
Pubbl/distr/stampa | Amsterdam, [Netherlands] : , : Academic Press, , 2016 |
Descrizione fisica | 1 online resource (1042 p.) |
Disciplina | 381.456646 |
Soggetto topico |
Dietary supplements industry - United States
Pharmaceutical industry - United States Vitamin industry - United States |
ISBN | 0-12-802165-9 |
Formato | Materiale a stampa ![]() |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto |
Front Cover; Nutraceuticals; Copyright Page; Dedication; Contents; List of Contributors; Introduction; Introduction; References; I. Applications of Nutraceuticals in Common Diseases and Disorders; 1 Nutraceuticals in CNS Diseases: Potential Mechanisms of Neuroprotection; Introduction; Polyphenols; Counteracting Oxidative Stress as a Mechanism of Neuroprotection; Direct Antioxidant Action of Quercetin; Potential Role of Hormesis in Neuroprotection; Modulation of the Nrf2-ARE Pathway as a Mechanism of Quercetin Neuroprotection
Modulation of Paraoxonase 2 (PON2) as a Potential Novel Mechanism of Quercetin NeuroprotectionParaoxonase 2; Paraoxonase 2 in the Central Nervous System; Gender Differences in Paraoxonase 2 Expression; Modulation of Paraoxonase 2; Modulation of Paraoxonase 2 by Quercetin; The Issue of Metabolites; Concluding Remarks and Future Directions; Acknowledgments; References; 2 Prevention of Neurodegenerative Disorders by Nutraceuticals; Introduction; Nutraceuticals for the Prevention and Amelioration of AD; Nutraceuticals for the Prevention and Amelioration of PD Nutraceuticals for the Prevention and Amelioration of ASDConcluding Remarks and Future Directions; References; 3 Cognitive Effects of Nutraceuticals; Introduction; Biological Basis of Cognition; Overview of Cognition; Cellular Basis of Information Storage; Synaptic Plasticity as a Physical Basis for Memory; Biological Basis of Dementia; Nutraceuticals with Potential Cognitive Enhancing Functions; Ginkgo biloba; Positive Effects; Potential Mechanisms; Negative or Null Effects; Bacopa monnieri; Positive Effects; Potential Mechanisms; Negative or Null Effects; Ginseng; Positive Effects Potential MechanismNegative or Null Effects; Phosphatidylserine; Positive Effects; Potential Mechanisms; Negative or Null Effects; Caffeine; Positive Effects; Potential Mechanisms; Negative or Null Effects; Centella asiatica, Ephedra sinica, and Crocus sativus; Potential Concerns of Cognitive Enhancement; Concluding Remarks and Future Directions; References; 4 Nutraceuticals in Cardiovascular Diseases; Introduction; Cardiac Dysfunction; Features of Cardiac Disease; Hypertension; Coronary Artery Disease (CAD)-Atherosclerosis; Ischemia; Hypertrophy; Oxidative Stress; Vascular Injury Biomarkers of Heart DiseaseTherapeutic Response to Heart Disease; Phytotherapeutic Strategies; Nutraceuticals; Cruciferous Vegetables; Bulbous Plants; Tea; CoQ10; Turmeric; Grape Skin; Fish Oil/Olive Oil; Vegetables; Carnitine; Soy; Concluding Remarks and Future Directions; References; 5 Antiatherosclerotic Efficacy of Nutraceuticals; Introduction; Pathogenesis of Atherosclerosis and Possible Points of Therapeutic Intervention; Role of LDL; Atherosclerotic Plaque Formation; Existing and Emerging Antiatherosclerotic Therapies; Nutraceuticals with Antiatherosclerotic Activity Antiatherogenic Natural Agents |
Record Nr. | UNINA-9910583463203321 |
Amsterdam, [Netherlands] : , : Academic Press, , 2016 | ||
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Lo trovi qui: Univ. Federico II | ||
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