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Genome-based therapeutics : targeted drug discovery and development : workshop summary / / Adam C. Berger and Steve Olson, Rapporteurs ; Roundtable on Translating Genomic-Based Research for Health, Board on Health Sciences Policy, Institute of Medicine of the National Academies
Genome-based therapeutics : targeted drug discovery and development : workshop summary / / Adam C. Berger and Steve Olson, Rapporteurs ; Roundtable on Translating Genomic-Based Research for Health, Board on Health Sciences Policy, Institute of Medicine of the National Academies
Pubbl/distr/stampa Washington, District of Columbia : , : National Academies Press, , [2012]
Descrizione fisica 1 online resource (109 p.)
Disciplina 615.1
Soggetto topico Drugs - United States - Design
Pharmaceutical technology - United States
Pharmaceutical industry - United States
Genomics - United States
ISBN 0-309-26027-2
0-309-26025-6
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Introduction -- The current landscape -- Case studies: The development of Crizotinib for treatment of non-small-cell lung cancer; Use of genetics to inform drug development for the treatment of schizophrenia; A genetic approach to the treatment of cystic fibrosis -- Emerging technologies in drug development: Large-scale whole-genome sequencing; The value of clinical next-generation sequencing to drug developers; The uses of genomic information -- Evolving paradigms: Foundations and drug development: an example; Genomics and regulatory science; Pharmacy benefit management and pharmacogenomics; Repurposing of drugs -- Forging collaborative strategies for the development of personalized medicine: The need for collaboration; FDA initiatives; NCATS initiatives; Biospecimens and databases; Reducing health disparities; Patient and physican education; An emphasis on the science.
Record Nr. UNINA-9910787308203321
Washington, District of Columbia : , : National Academies Press, , [2012]
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Genome-based therapeutics : targeted drug discovery and development : workshop summary / / Adam C. Berger and Steve Olson, Rapporteurs ; Roundtable on Translating Genomic-Based Research for Health, Board on Health Sciences Policy, Institute of Medicine of the National Academies
Genome-based therapeutics : targeted drug discovery and development : workshop summary / / Adam C. Berger and Steve Olson, Rapporteurs ; Roundtable on Translating Genomic-Based Research for Health, Board on Health Sciences Policy, Institute of Medicine of the National Academies
Pubbl/distr/stampa Washington, District of Columbia : , : National Academies Press, , [2012]
Descrizione fisica 1 online resource (109 p.)
Disciplina 615.1
Soggetto topico Drugs - United States - Design
Pharmaceutical technology - United States
Pharmaceutical industry - United States
Genomics - United States
ISBN 0-309-26027-2
0-309-26025-6
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Introduction -- The current landscape -- Case studies: The development of Crizotinib for treatment of non-small-cell lung cancer; Use of genetics to inform drug development for the treatment of schizophrenia; A genetic approach to the treatment of cystic fibrosis -- Emerging technologies in drug development: Large-scale whole-genome sequencing; The value of clinical next-generation sequencing to drug developers; The uses of genomic information -- Evolving paradigms: Foundations and drug development: an example; Genomics and regulatory science; Pharmacy benefit management and pharmacogenomics; Repurposing of drugs -- Forging collaborative strategies for the development of personalized medicine: The need for collaboration; FDA initiatives; NCATS initiatives; Biospecimens and databases; Reducing health disparities; Patient and physican education; An emphasis on the science.
Record Nr. UNINA-9910824065303321
Washington, District of Columbia : , : National Academies Press, , [2012]
Materiale a stampa
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Improving drug pricing transparency and lowering prices for American consumers : hearing before the Subcommittee on Health of the Committee on Energy and Commerce, House of Representatives, One Hundred Sixteenth Congress, first session, May 21, 2019
Improving drug pricing transparency and lowering prices for American consumers : hearing before the Subcommittee on Health of the Committee on Energy and Commerce, House of Representatives, One Hundred Sixteenth Congress, first session, May 21, 2019
Pubbl/distr/stampa Washington : , : U.S. Government Publishing Office, , 2021
Descrizione fisica 1 online resource (vi, 187 pages) : color illustrations
Soggetto topico Drugs - Prices - United States
Pharmaceutical industry - United States
Prescription pricing - United States
Prescription pricing - Law and legislation - United States
Insurance premiums - Law and legislation - United States
Soggetto genere / forma Legislative hearings.
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Altri titoli varianti Improving drug pricing transparency and lowering prices for American consumers
Record Nr. UNINA-9910716543703321
Washington : , : U.S. Government Publishing Office, , 2021
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Journal of research in pharmaceutical economics
Journal of research in pharmaceutical economics
Pubbl/distr/stampa [Binghamton, NY], : Haworth Press, [©1989]-©2001
Descrizione fisica 1 online resource
Disciplina 338.4/76151/097305
Soggetto topico Pharmaceutical industry - United States
Pharmaceutical industry
Drug Industry - economics
Soggetto genere / forma Periodicals
Periodicals.
Formato Materiale a stampa
Livello bibliografico Periodico
Lingua di pubblicazione eng
Altri titoli varianti Pharmaceutical economics
Record Nr. UNINA-9910219649703321
[Binghamton, NY], : Haworth Press, [©1989]-©2001
Materiale a stampa
Lo trovi qui: Univ. Federico II
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Legislative proposal to increase funding for medical research : hearing before a subcommittee of the Committee on Appropriations, United States Senate, One Hundred Fifth Congress, first session, special hearing
Legislative proposal to increase funding for medical research : hearing before a subcommittee of the Committee on Appropriations, United States Senate, One Hundred Fifth Congress, first session, special hearing
Pubbl/distr/stampa Washington : , : U.S. Government Printing Office, , 1998
Descrizione fisica 1 online resource (iii, 35, pages)
Collana S. hrg.
Soggetto topico Drugs - Research - United States - Finance
Medicine - Research - United States
Pharmaceutical industry - United States
Pharmaceutical policy - United States
Science and state - United States
Soggetto genere / forma Legislative hearings.
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Record Nr. UNINA-9910714005503321
Washington : , : U.S. Government Printing Office, , 1998
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Lowering the cost of prescription drugs : reducing barriers to market competition : hearing before the Subcommittee on Health of the Committee on Energy and Commerce, House of Representatives, One Hundred Sixteenth Congress, first session, March 13, 2019
Lowering the cost of prescription drugs : reducing barriers to market competition : hearing before the Subcommittee on Health of the Committee on Energy and Commerce, House of Representatives, One Hundred Sixteenth Congress, first session, March 13, 2019
Pubbl/distr/stampa Washington : , : U.S. Government Publishing Office, , 2021
Descrizione fisica 1 online resource (vi, 246 pages)
Soggetto topico Prescription pricing - United States - Public opinion
Drugs - Generic substitution - Law and legislation - United States
Drugs - Law and legislation - United States
Drugs - United States - Patents
Patent laws and legislation - United States
Competition - United States
Pharmaceutical industry - United States
Soggetto genere / forma Legislative hearings.
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Altri titoli varianti Lowering the cost of prescription drugs
Record Nr. UNINA-9910715471103321
Washington : , : U.S. Government Publishing Office, , 2021
Materiale a stampa
Lo trovi qui: Univ. Federico II
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Making health care more affordable : lowering drug prices and increasing transparency : hearing before the Subcommittee on Health, Employment, Labor and Pensions, Committee on Education and Labor, U.S. House of Representatives, One Hundred Sixteenth Congress, first session : hearing held in Washington, DC, September 26, 2019
Making health care more affordable : lowering drug prices and increasing transparency : hearing before the Subcommittee on Health, Employment, Labor and Pensions, Committee on Education and Labor, U.S. House of Representatives, One Hundred Sixteenth Congress, first session : hearing held in Washington, DC, September 26, 2019
Pubbl/distr/stampa Washington : , : U.S. Government Publishing Office, , 2021
Descrizione fisica 1 online resource (iv, 175 pages) : color illustrations
Soggetto topico Prescription pricing - United States
Drugs - Prices - United States
Pharmaceutical industry - United States
Social responsibility of business - United States
Drugs - Prices
Pharmaceutical industry
Prescription pricing
Social responsibility of business
Soggetto genere / forma Legislative hearings.
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Altri titoli varianti Making health care more affordable
Record Nr. UNINA-9910715252803321
Washington : , : U.S. Government Publishing Office, , 2021
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Manufacturer safeguards may not prevent copayment coupon use for Part D drugs
Manufacturer safeguards may not prevent copayment coupon use for Part D drugs
Pubbl/distr/stampa Washington, DC : , : Department of Health and Human Services, Office of Inspector General, , 2014
Descrizione fisica 1 online resource (29 pages) : color illustrations
Soggetto topico Medicare - Claims administration
Pharmaceutical industry - United States
Nonprescription drug industry - United States
Copayments (Insurance) - Law and legislation - United States
Drugs - Prices - United States
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Altri titoli varianti Manufacturer safeguards may not prevent copayment coupon use for Part D drugs
Record Nr. UNINA-9910707259203321
Washington, DC : , : Department of Health and Human Services, Office of Inspector General, , 2014
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National Centers of Excellence in Continuous Pharmaceutical Manufacturing Act of 2020 : report (to accompany H.R. 4866)
National Centers of Excellence in Continuous Pharmaceutical Manufacturing Act of 2020 : report (to accompany H.R. 4866)
Pubbl/distr/stampa [Washington, D.C.] : , : [U.S. Government Publishing Office], , [2020]
Descrizione fisica 1 online resource (16 pages)
Disciplina 1.1/8:116-513
Collana Report / 116th Congress, 2d session, House of Representatives
Soggetto topico Pharmaceutical technology - United States
Pharmaceutical industry - United States
Pharmaceutical industry
Pharmaceutical technology
Soggetto genere / forma Legislative materials.
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Altri titoli varianti National Centers of Excellence in Continuous Pharmaceutical Manufacturing Act of 2020
Record Nr. UNINA-9910715152703321
[Washington, D.C.] : , : [U.S. Government Publishing Office], , [2020]
Materiale a stampa
Lo trovi qui: Univ. Federico II
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Nutraceuticals : efficacy, safety and toxicity / / edited by Ramesh C. Gupta
Nutraceuticals : efficacy, safety and toxicity / / edited by Ramesh C. Gupta
Pubbl/distr/stampa Amsterdam, [Netherlands] : , : Academic Press, , 2016
Descrizione fisica 1 online resource (1042 p.)
Disciplina 381.456646
Soggetto topico Dietary supplements industry - United States
Pharmaceutical industry - United States
Vitamin industry - United States
ISBN 0-12-802165-9
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Front Cover; Nutraceuticals; Copyright Page; Dedication; Contents; List of Contributors; Introduction; Introduction; References; I. Applications of Nutraceuticals in Common Diseases and Disorders; 1 Nutraceuticals in CNS Diseases: Potential Mechanisms of Neuroprotection; Introduction; Polyphenols; Counteracting Oxidative Stress as a Mechanism of Neuroprotection; Direct Antioxidant Action of Quercetin; Potential Role of Hormesis in Neuroprotection; Modulation of the Nrf2-ARE Pathway as a Mechanism of Quercetin Neuroprotection
Modulation of Paraoxonase 2 (PON2) as a Potential Novel Mechanism of Quercetin NeuroprotectionParaoxonase 2; Paraoxonase 2 in the Central Nervous System; Gender Differences in Paraoxonase 2 Expression; Modulation of Paraoxonase 2; Modulation of Paraoxonase 2 by Quercetin; The Issue of Metabolites; Concluding Remarks and Future Directions; Acknowledgments; References; 2 Prevention of Neurodegenerative Disorders by Nutraceuticals; Introduction; Nutraceuticals for the Prevention and Amelioration of AD; Nutraceuticals for the Prevention and Amelioration of PD
Nutraceuticals for the Prevention and Amelioration of ASDConcluding Remarks and Future Directions; References; 3 Cognitive Effects of Nutraceuticals; Introduction; Biological Basis of Cognition; Overview of Cognition; Cellular Basis of Information Storage; Synaptic Plasticity as a Physical Basis for Memory; Biological Basis of Dementia; Nutraceuticals with Potential Cognitive Enhancing Functions; Ginkgo biloba; Positive Effects; Potential Mechanisms; Negative or Null Effects; Bacopa monnieri; Positive Effects; Potential Mechanisms; Negative or Null Effects; Ginseng; Positive Effects
Potential MechanismNegative or Null Effects; Phosphatidylserine; Positive Effects; Potential Mechanisms; Negative or Null Effects; Caffeine; Positive Effects; Potential Mechanisms; Negative or Null Effects; Centella asiatica, Ephedra sinica, and Crocus sativus; Potential Concerns of Cognitive Enhancement; Concluding Remarks and Future Directions; References; 4 Nutraceuticals in Cardiovascular Diseases; Introduction; Cardiac Dysfunction; Features of Cardiac Disease; Hypertension; Coronary Artery Disease (CAD)-Atherosclerosis; Ischemia; Hypertrophy; Oxidative Stress; Vascular Injury
Biomarkers of Heart DiseaseTherapeutic Response to Heart Disease; Phytotherapeutic Strategies; Nutraceuticals; Cruciferous Vegetables; Bulbous Plants; Tea; CoQ10; Turmeric; Grape Skin; Fish Oil/Olive Oil; Vegetables; Carnitine; Soy; Concluding Remarks and Future Directions; References; 5 Antiatherosclerotic Efficacy of Nutraceuticals; Introduction; Pathogenesis of Atherosclerosis and Possible Points of Therapeutic Intervention; Role of LDL; Atherosclerotic Plaque Formation; Existing and Emerging Antiatherosclerotic Therapies; Nutraceuticals with Antiatherosclerotic Activity
Antiatherogenic Natural Agents
Record Nr. UNINA-9910583463203321
Amsterdam, [Netherlands] : , : Academic Press, , 2016
Materiale a stampa
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