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Journal of peptide science
Journal of peptide science
Pubbl/distr/stampa [Chichester, West Sussex, UK], : European Peptide Society, : John Wiley & Sons, c1995-
Disciplina 616
Soggetto topico Peptides
Peptides - Périodiques
Soggetto genere / forma Periodical
ISSN 1099-1387
Formato Materiale a stampa
Livello bibliografico Periodico
Lingua di pubblicazione eng
Record Nr. UNISA-996209149303316
[Chichester, West Sussex, UK], : European Peptide Society, : John Wiley & Sons, c1995-
Materiale a stampa
Lo trovi qui: Univ. di Salerno
Opac: Controlla la disponibilità qui
Journal of peptide science
Journal of peptide science
Pubbl/distr/stampa [Chichester, West Sussex, UK], : European Peptide Society, : John Wiley & Sons, c1995-
Disciplina 616
Soggetto topico Peptides
Peptides - Périodiques
Soggetto genere / forma Periodical
ISSN 1099-1387
Formato Materiale a stampa
Livello bibliografico Periodico
Lingua di pubblicazione eng
Record Nr. UNINA-9910144574303321
[Chichester, West Sussex, UK], : European Peptide Society, : John Wiley & Sons, c1995-
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Molecular orbital calculations for biological systems [[electronic resource] /] / edited by Anne-Marie Sapse
Molecular orbital calculations for biological systems [[electronic resource] /] / edited by Anne-Marie Sapse
Pubbl/distr/stampa New York, : Oxford University Press, 1998
Descrizione fisica 1 online resource (248 p.)
Disciplina 541.280285
547.70448
547/.70448
Altri autori (Persone) SapseAnne-Marie
Collana Topics in physical chemistry
Soggetto topico Molecular orbitals
Biomolecules
Peptides
Amino acids
Antineoplastic agents
Soggetto genere / forma Electronic books.
ISBN 0-19-756089-X
1-280-52822-2
9786610528226
0-19-535684-5
1-4294-0426-4
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Contents; Contributors; Introduction; 1 Ab Initio Calculations; 2 An Introduction to the Theoretical Basis of Semi-Empirical Quantum-Mechanical Methods for Biological Chemists; 3 The Molecular Electrostatic Potential: A Tool for Understanding and Predicting Molecular Interactions; 4 Applications of Density Functional Theory to Biological Systems; 5 On Comparing Experimental and Calculated Structural Parameters; 6 Ab Initio Studies of Anti-Cancer Drugs; 7 Ab Initio Calculations of Amino Acids and Peptides; Index; A; B; C; D; E; F; G; H; I; K; L; M; N; O; P; R; S; T; U; V; W; X; Z
Record Nr. UNINA-9910450829303321
New York, : Oxford University Press, 1998
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Molecular orbital calculations for biological systems [[electronic resource] /] / edited by Anne-Marie Sapse
Molecular orbital calculations for biological systems [[electronic resource] /] / edited by Anne-Marie Sapse
Pubbl/distr/stampa New York, : Oxford University Press, 1998
Descrizione fisica 1 online resource (248 p.)
Disciplina 541.280285
547.70448
547/.70448
Altri autori (Persone) SapseAnne-Marie
Collana Topics in physical chemistry
Soggetto topico Molecular orbitals
Biomolecules
Peptides
Amino acids
Antineoplastic agents
ISBN 0-19-756089-X
1-280-52822-2
9786610528226
0-19-535684-5
1-4294-0426-4
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Contents; Contributors; Introduction; 1 Ab Initio Calculations; 2 An Introduction to the Theoretical Basis of Semi-Empirical Quantum-Mechanical Methods for Biological Chemists; 3 The Molecular Electrostatic Potential: A Tool for Understanding and Predicting Molecular Interactions; 4 Applications of Density Functional Theory to Biological Systems; 5 On Comparing Experimental and Calculated Structural Parameters; 6 Ab Initio Studies of Anti-Cancer Drugs; 7 Ab Initio Calculations of Amino Acids and Peptides; Index; A; B; C; D; E; F; G; H; I; K; L; M; N; O; P; R; S; T; U; V; W; X; Z
Record Nr. UNINA-9910784807203321
New York, : Oxford University Press, 1998
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Molecular orbital calculations for biological systems [[electronic resource] /] / edited by Anne-Marie Sapse
Molecular orbital calculations for biological systems [[electronic resource] /] / edited by Anne-Marie Sapse
Edizione [1st ed.]
Pubbl/distr/stampa New York, : Oxford University Press, 1998
Descrizione fisica 1 online resource (248 p.)
Disciplina 541.280285
547.70448
547/.70448
Altri autori (Persone) SapseAnne-Marie
Collana Topics in physical chemistry
Soggetto topico Molecular orbitals
Biomolecules
Peptides
Amino acids
Antineoplastic agents
ISBN 0-19-756089-X
1-280-52822-2
9786610528226
0-19-535684-5
1-4294-0426-4
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Contents; Contributors; Introduction; 1 Ab Initio Calculations; 2 An Introduction to the Theoretical Basis of Semi-Empirical Quantum-Mechanical Methods for Biological Chemists; 3 The Molecular Electrostatic Potential: A Tool for Understanding and Predicting Molecular Interactions; 4 Applications of Density Functional Theory to Biological Systems; 5 On Comparing Experimental and Calculated Structural Parameters; 6 Ab Initio Studies of Anti-Cancer Drugs; 7 Ab Initio Calculations of Amino Acids and Peptides; Index; A; B; C; D; E; F; G; H; I; K; L; M; N; O; P; R; S; T; U; V; W; X; Z
Record Nr. UNINA-9910824725203321
New York, : Oxford University Press, 1998
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Naturally processed peptides
Naturally processed peptides
Pubbl/distr/stampa [Place of publication not identified], : Karger, 1993
Descrizione fisica 1 online resource (XII + 240 pages) : : 26 figures, 38 tables
Soggetto topico Amino Acids, Peptides, and Proteins
Chemicals and Drugs
Peptides
ISBN 3-318-01493-1
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Record Nr. UNINA-9910155287203321
[Place of publication not identified], : Karger, 1993
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Origins and Synthesis of Amino Acids. Vol. 1
Origins and Synthesis of Amino Acids. Vol. 1
Autore Hughes William
Pubbl/distr/stampa [Place of publication not identified], : Wiley VCH Imprint, 2009
Descrizione fisica 1 online resource (xix, 701 pages)
Disciplina 547.750459
Soggetto topico Amino acids - Synthesis
Amino acids
Peptides
Proteins
ISBN 3-527-63176-3
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto List of Contributors XV 1 Mass Spectrometry of Amino Acids and Proteins 1 Simin D. Maleknia and Richard Johnson 1.1 Introduction 1 1.2 Basic Protein Chemistry and How it Relates to MS 21 1.3 Sample Preparation and Data Acquisition 28 1.4 Data Analysis of LC-MS/MS (or CE-MS/MS) of Mixtures 32 1.5 MS of Protein Structure, Folding, and Interactions 36 1.6 Conclusions and Perspectives 40 References 40 2 X-Ray Structure Determination of Proteins and Peptides 51 Andrew J. Fisher 2.1 Introduction 51 2.2 Growing Crystals 55 2.3 Symmetry and Space Groups 62 2.4 X-Ray Scattering and Diffraction 67 2.5 Collecting and Processing Diffraction Data 82 2.6 Solving the Structure (Determining Phases) 83 2.7 Analyzing and Refining the Structure 90 References 94 3 Nuclear Magnetic Resonance of Amino Acids, Peptides, and Proteins 97 Andrea Bernini and Pierandrea Temussi 3.1 Introduction 97 3.2 Amino Acids 101 3.3 Peptides 113 3.4 Proteins 129 3.5 Conclusions 145 References 146 4 Structure and Activity of N-Methylated Peptides 155 Raymond S. Norton 4.1 Introduction 155 4.2 Conformational Effects of N-Methylation 157 4.3 Effects of N-Methylation on Bioactive Peptides 159 4.4 Concluding Remarks 162 References 163 5 High-Performance Liquid Chromatography of Peptides and Proteins 167 Reinhard I. Boysen and Milton T.W. Hearn 5.1 Introduction 167 5.2 Basic Terms and Concepts in Chromatography 169 5.3 Chemical Structure of Peptides and Proteins 173 5.4 HPLC Separation Modes in Peptide and Protein Analysis 177 5.5 Method Development from Analytical to Preparative Scale Illustrated for HP-RPC 189 5.6 Multidimensional HPLC 198 5.7 Conclusions 206 References 207 6 Local Surface Plasmon Resonance and Electrochemical Biosensing Systems for Analyzing Functional Peptides 211 Masato Saito and Eiichi Tamiya 6.1 Localized Surface Plasmon Resonance (LSPR)-Based Microfluidics Biosensor for the Detection of Insulin Peptide Hormone 211 6.2 Electrochemical LSPR-Based Label-Free Detection of Melittin 215 6.3 Label-Free Electrochemical Monitoring of b-Amyloid (Ab) Peptide Aggregation 218 References 221 7 Surface Plasmon Resonance Spectroscopy in the Biosciences 225 Jing Yuan, Yinqiu Wu, and Marie-Isabel Aguilar 7.1 Introduction 225 7.2 SPR-Based Optical Biosensors 225 7.3 Principle of Operation of SPR Biosensors 226 7.4 Description of a SPR Instrument 228 7.5 Application of SPR in Immunosensor Design 230 7.6 Application of SPR in Membrane Interactions 234 7.7 Data Analysis 240 7.8 Conclusions 243 References 244 8 Atomic Force Microscopy of Proteins 249 Adam Mechler 8.1 Foreword 249 8.2 AFM 250 8.3 Bioimaging Highlights 253 8.4 Issues 261 8.5 Force Measurements 269 8.6 Liquid Imaging 269 8.7 Sample Preparation for Bioimaging 272 8.8 Outlook 274 References 275 9 Solvent Interactions with Proteins and Other Macromolecules 277 Satoshi Ohtake, Yoshiko Kita, Kouhei Tsumoto, and Tsutomu Arakawa 9.1 Introduction 277 9.2 Solvent Applications 280 9.3 Solvent Application for Viruses 300 9.4 Solvent Application for DNA 310 9.5 Mechanism 314 9.6 Protein-Solvent Interactions in Frozen and Freeze-Dried Systems 342 9.7 Conclusions 348 References 349 10 Role of Cysteine 361 Lalla A. Ba, Torsten Burkholz, Thomas Schneider, and Claus Jacob 10.1 Sulfur: A Redox Chameleon with Many Faces 361 10.2 Three Faces of Thiols: Nucleophilicity, Redox Activity, and Metal Binding 365 10.3 Towards a Dynamic Picture of Disulfide Bonds 371 10.4 Chemical Protection and Regulation via S-Thiolation 374 10.5 ''Dormant'' Catalytic Sites 378 10.6 Peroxiredoxin/Sulfiredoxin Catalysis and Control Pathway 379 10.7 Higher Sulfur Oxidation States: From the Shadows to the Heart of Biological Sulfur Chemistry 384 10.8 Cysteine as a Target for Oxidants, Metal Ions, and Drug Molecules 388 10.9 Conclusions and Outlook 390 References 391 11 Role of Disulfide Bonds in Peptide and Protein Conformation 395 Keith K. Khoo and Raymond S. Norton 11.1 Introduction 395 11.2 Probing the Role of Disulfide Bonds 396 11.3 Contribution of Disulfide Bonds to Protein Stability 396 11.4 Role of Disulfide Bonds in Protein Folding 397 11.5 Role of Individual Disulfide Bonds in Protein Structure 399 11.6 Disulfide Bonds in Protein Dynamics 401 11.7 Disulfide Bonding Patterns and Protein Topology 403 11.8 Applications 408 11.9 Conclusions 409 References 410 12 Quantitative Mass Spectrometry-Based Proteomics 419 Shao-En Ong 12.1 Introduction 419 12.2 Quantification in Biological MS 420 12.3 Identifying Proteins Interacting with Small Molecules with Quantitative Proteomics 430 12.4 Conclusions 433 References 434 13 Two-Dimensional Gel Electrophoresis and Protein/Polypeptide Assignment 439 Takashi Manabe and Ya Jin 13.1 Introduction 439 13.2 Aim of Protein Analysis and Development of 2-DE Techniques 439 13.3 Current Status of 2-DE Techniques 441 13.4 Development of Protein Assignment Techniques on 2-DE Gels and Current Status of Mass Spectrometric Techniques 452 13.5 Conclusions 460 References 460 14 Bioinformatics Tools for Detecting Post-Translational Modifications in Mass Spectrometry Data 463 Patricia M. Palagi, Erik Arhné, MarKus Müller, and Frédérique Lisacek 14.1 Introduction 463 14.2 PTM Discovery with MS 465 14.3 Database Resources for PTM Analysis 470 14.4 Conclusions 473 References 473 Index 477.
Record Nr. UNINA-9910830308003321
Hughes William  
[Place of publication not identified], : Wiley VCH Imprint, 2009
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Origins and Synthesis of Amino Acids. Vol. 1
Origins and Synthesis of Amino Acids. Vol. 1
Autore Hughes William
Pubbl/distr/stampa [Place of publication not identified], : Wiley VCH Imprint, 2009
Descrizione fisica 1 online resource (xix, 701 pages)
Disciplina 547.750459
Soggetto topico Amino acids - Synthesis
Amino acids
Peptides
Proteins
ISBN 3-527-63176-3
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto List of Contributors XV 1 Mass Spectrometry of Amino Acids and Proteins 1 Simin D. Maleknia and Richard Johnson 1.1 Introduction 1 1.2 Basic Protein Chemistry and How it Relates to MS 21 1.3 Sample Preparation and Data Acquisition 28 1.4 Data Analysis of LC-MS/MS (or CE-MS/MS) of Mixtures 32 1.5 MS of Protein Structure, Folding, and Interactions 36 1.6 Conclusions and Perspectives 40 References 40 2 X-Ray Structure Determination of Proteins and Peptides 51 Andrew J. Fisher 2.1 Introduction 51 2.2 Growing Crystals 55 2.3 Symmetry and Space Groups 62 2.4 X-Ray Scattering and Diffraction 67 2.5 Collecting and Processing Diffraction Data 82 2.6 Solving the Structure (Determining Phases) 83 2.7 Analyzing and Refining the Structure 90 References 94 3 Nuclear Magnetic Resonance of Amino Acids, Peptides, and Proteins 97 Andrea Bernini and Pierandrea Temussi 3.1 Introduction 97 3.2 Amino Acids 101 3.3 Peptides 113 3.4 Proteins 129 3.5 Conclusions 145 References 146 4 Structure and Activity of N-Methylated Peptides 155 Raymond S. Norton 4.1 Introduction 155 4.2 Conformational Effects of N-Methylation 157 4.3 Effects of N-Methylation on Bioactive Peptides 159 4.4 Concluding Remarks 162 References 163 5 High-Performance Liquid Chromatography of Peptides and Proteins 167 Reinhard I. Boysen and Milton T.W. Hearn 5.1 Introduction 167 5.2 Basic Terms and Concepts in Chromatography 169 5.3 Chemical Structure of Peptides and Proteins 173 5.4 HPLC Separation Modes in Peptide and Protein Analysis 177 5.5 Method Development from Analytical to Preparative Scale Illustrated for HP-RPC 189 5.6 Multidimensional HPLC 198 5.7 Conclusions 206 References 207 6 Local Surface Plasmon Resonance and Electrochemical Biosensing Systems for Analyzing Functional Peptides 211 Masato Saito and Eiichi Tamiya 6.1 Localized Surface Plasmon Resonance (LSPR)-Based Microfluidics Biosensor for the Detection of Insulin Peptide Hormone 211 6.2 Electrochemical LSPR-Based Label-Free Detection of Melittin 215 6.3 Label-Free Electrochemical Monitoring of b-Amyloid (Ab) Peptide Aggregation 218 References 221 7 Surface Plasmon Resonance Spectroscopy in the Biosciences 225 Jing Yuan, Yinqiu Wu, and Marie-Isabel Aguilar 7.1 Introduction 225 7.2 SPR-Based Optical Biosensors 225 7.3 Principle of Operation of SPR Biosensors 226 7.4 Description of a SPR Instrument 228 7.5 Application of SPR in Immunosensor Design 230 7.6 Application of SPR in Membrane Interactions 234 7.7 Data Analysis 240 7.8 Conclusions 243 References 244 8 Atomic Force Microscopy of Proteins 249 Adam Mechler 8.1 Foreword 249 8.2 AFM 250 8.3 Bioimaging Highlights 253 8.4 Issues 261 8.5 Force Measurements 269 8.6 Liquid Imaging 269 8.7 Sample Preparation for Bioimaging 272 8.8 Outlook 274 References 275 9 Solvent Interactions with Proteins and Other Macromolecules 277 Satoshi Ohtake, Yoshiko Kita, Kouhei Tsumoto, and Tsutomu Arakawa 9.1 Introduction 277 9.2 Solvent Applications 280 9.3 Solvent Application for Viruses 300 9.4 Solvent Application for DNA 310 9.5 Mechanism 314 9.6 Protein-Solvent Interactions in Frozen and Freeze-Dried Systems 342 9.7 Conclusions 348 References 349 10 Role of Cysteine 361 Lalla A. Ba, Torsten Burkholz, Thomas Schneider, and Claus Jacob 10.1 Sulfur: A Redox Chameleon with Many Faces 361 10.2 Three Faces of Thiols: Nucleophilicity, Redox Activity, and Metal Binding 365 10.3 Towards a Dynamic Picture of Disulfide Bonds 371 10.4 Chemical Protection and Regulation via S-Thiolation 374 10.5 ''Dormant'' Catalytic Sites 378 10.6 Peroxiredoxin/Sulfiredoxin Catalysis and Control Pathway 379 10.7 Higher Sulfur Oxidation States: From the Shadows to the Heart of Biological Sulfur Chemistry 384 10.8 Cysteine as a Target for Oxidants, Metal Ions, and Drug Molecules 388 10.9 Conclusions and Outlook 390 References 391 11 Role of Disulfide Bonds in Peptide and Protein Conformation 395 Keith K. Khoo and Raymond S. Norton 11.1 Introduction 395 11.2 Probing the Role of Disulfide Bonds 396 11.3 Contribution of Disulfide Bonds to Protein Stability 396 11.4 Role of Disulfide Bonds in Protein Folding 397 11.5 Role of Individual Disulfide Bonds in Protein Structure 399 11.6 Disulfide Bonds in Protein Dynamics 401 11.7 Disulfide Bonding Patterns and Protein Topology 403 11.8 Applications 408 11.9 Conclusions 409 References 410 12 Quantitative Mass Spectrometry-Based Proteomics 419 Shao-En Ong 12.1 Introduction 419 12.2 Quantification in Biological MS 420 12.3 Identifying Proteins Interacting with Small Molecules with Quantitative Proteomics 430 12.4 Conclusions 433 References 434 13 Two-Dimensional Gel Electrophoresis and Protein/Polypeptide Assignment 439 Takashi Manabe and Ya Jin 13.1 Introduction 439 13.2 Aim of Protein Analysis and Development of 2-DE Techniques 439 13.3 Current Status of 2-DE Techniques 441 13.4 Development of Protein Assignment Techniques on 2-DE Gels and Current Status of Mass Spectrometric Techniques 452 13.5 Conclusions 460 References 460 14 Bioinformatics Tools for Detecting Post-Translational Modifications in Mass Spectrometry Data 463 Patricia M. Palagi, Erik Arhné, MarKus Müller, and Frédérique Lisacek 14.1 Introduction 463 14.2 PTM Discovery with MS 465 14.3 Database Resources for PTM Analysis 470 14.4 Conclusions 473 References 473 Index 477.
Record Nr. UNINA-9910840789903321
Hughes William  
[Place of publication not identified], : Wiley VCH Imprint, 2009
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Peptide applications in biomedicine, biotechnology and bioengineering / / edited by Sotirios Koutsopoulos
Peptide applications in biomedicine, biotechnology and bioengineering / / edited by Sotirios Koutsopoulos
Pubbl/distr/stampa Duxford, England : , : Woodhead Publishing, , 2018
Descrizione fisica 1 online resource (640 pages) : illustrations
Disciplina 612.01575
Collana Woodhead Publishing Series in Biomaterials
Soggetto topico Peptides
ISBN 0-08-100736-1
0-08-100742-6
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Record Nr. UNINA-9910297397603321
Duxford, England : , : Woodhead Publishing, , 2018
Materiale a stampa
Lo trovi qui: Univ. Federico II
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Peptide materials [[electronic resource] ] : from nanostuctures to applications / / edited by Carlos Alemán and Alberto Bianco and Mariano Venanzi
Peptide materials [[electronic resource] ] : from nanostuctures to applications / / edited by Carlos Alemán and Alberto Bianco and Mariano Venanzi
Edizione [First edition.]
Pubbl/distr/stampa Chichester [England], : Wiley, 2013
Descrizione fisica 1 online resource (494 p.)
Disciplina 572.65
Altri autori (Persone) AlemánCarlos
BiancoAlberto
VenanziMariano
Soggetto topico Peptides
ISBN 1-118-59241-7
1-118-59240-9
1-299-44994-8
1-118-59242-5
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto pt. 1. Fundamentals of peptide materials -- pt. 2. Peptide nanostructures -- pt. 3. Peptide conjugates and hybrid materials -- pt. 4. Applications of peptide materials.
Record Nr. UNINA-9910139023303321
Chichester [England], : Wiley, 2013
Materiale a stampa
Lo trovi qui: Univ. Federico II
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