Advances in Agri-Food Biotechnology [[electronic resource] /] / edited by Tilak Raj Sharma, Rupesh Deshmukh, Humira Sonah |
Edizione | [1st ed. 2020.] |
Pubbl/distr/stampa | Singapore : , : Springer Singapore : , : Imprint : Springer, , 2020 |
Descrizione fisica | 1 online resource (451 pages) |
Disciplina | 338.16 |
Soggetto topico |
Agriculture
Microbiology Plant physiology Plant breeding Food Microbiology Plant Physiology Plant Breeding/Biotechnology Genètica vegetal Agricultura Nutrició Biotecnologia agrícola |
Soggetto genere / forma | Llibres electrònics |
ISBN | 981-15-2874-8 |
Formato | Materiale a stampa ![]() |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto | Chapter 1. Global Perspective on Agriculture-Food Security and Nutrition -- Chapter 2. Advanced Approaches for Biofortification -- Chapter 3. Biofortification for Nutrient Content and Aroma Enrichment in Rice (Oryza sativa L.) -- Chapter 4. Biofortification in Pulses -- Chapter 5. Biofortification in Vegetables -- Chapter 6. Biofortification in Fruits -- Chapter 7. Transgenic Bio-fortified Crops: Applicability and Challenges -- Chapter 8. Biofortification in Fodder crops -- Chapter 9. Global Scenario of Vitamin Deficiency and Human Health -- Chapter 10. Plant Polyphenols and Gut Bacteria: Role in Obesity-induced Metabolic Endotoxaemia and Inflammation. Chapter 11. Designer Microbes for Nutraceutical Application -- Chapter 12. Nutrigenomics Approaches to Control Metabolic Diseases and Challenges to Personalized Nutritional Intervention -- Chapter 13. Biotechnological Advances for Phytoremediation -- Chapter 14. Diagnostic Tools for Food Safety -- Chapter 15. Nanotechnology for Food: Regulatory Issues and Challenges.Chapter 16. Advances in Edible Fruits Coating Materials -- Chapter 17. Systems Biology Approaches for Food and Health -- Chapter 18. Advances of Next Generation Sequencing (NGS) technologies to enhanced the Biofortifications in crops. |
Record Nr. | UNINA-9910416095603321 |
Singapore : , : Springer Singapore : , : Imprint : Springer, , 2020 | ||
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Lo trovi qui: Univ. Federico II | ||
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Advances in precision nutrition, personalization and health aging / / Alexander G. Haslberger |
Autore | Haslberger Alexander G. |
Pubbl/distr/stampa | Cham, Switzerland : , : Springer, , [2022] |
Descrizione fisica | 1 online resource (302 pages) |
Disciplina | 612.67 |
Soggetto topico |
Aging - Nutritional aspects
Older people - Nutrition Nutrició Vellesa Persones grans |
Soggetto genere / forma | Llibres electrònics |
ISBN |
9783031101533
9783031101526 |
Formato | Materiale a stampa ![]() |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto |
Intro -- Foreword -- Reference -- Contents -- 1 Trends in Personalised Precision Nutrition, Objectives -- 1.1 The Rise of Molecular Nutrition -- 1.2 The Way to Personalisation -- 1.3 Consequences of Personalisation -- References -- 2 Individualization, Precision Nutrition Developments for the 21st Century -- 2.1 Introduction -- 2.2 Evolution of Nutrition Science in the 20th Century Toward Personalization -- 2.2.1 Nutrition in the Post-genomic Era -- 2.2.2 New Horizons in Personalized Nutrition -- 2.3 Individualization and Food Choices Based on Personalized/Precision Nutrition and Involvement of Diet in Chronic Diseases -- 2.4 Translating Personalized Nutrition for Society -- 2.4.1 Social Impact Regarding PN -- 2.4.2 PN-Associated Business and Value Creation Models -- 2.4.3 Social Concerns and Their Impact on PN Development -- 2.4.4 Consumer Attitudes Toward Personalized Nutrition -- 2.5 Future Outlook -- 2.6 Concluding Remarks -- 2.7 Financial Support -- References -- 3 Precision Nutrition from the View of Genetics and Epigenetics -- 3.1 Introduction -- 3.2 Nutrigenetics and Nutrigenomics -- 3.3 Epigenetic Mechanisms -- 3.4 The DOHaD Theory: The Importance of the Maternal Diet in Animal and Human Models -- 3.5 Epigenetic Mechanisms and Nutrients -- 3.6 Epigenetic Mechanisms of Antioxidants -- 3.7 Aging, Epigenetics, Nutrition -- 3.8 The Importance of the Gender in Precision Nutrition Medicine -- 3.9 Concluding Remarks -- References -- 4 Precision Nutrition from the View of the Gut Microbiome -- 4.1 Introduction -- 4.2 The Human Gut Microbiome-(Un)limited Possibilities for Improving Human Health -- 4.3 Exploring the Human Gut Microbiome: Start Low Go Slow-Advances in Microbiome Research -- 4.3.1 Eubiosis versus Dysbiosis -- 4.4 The Microbiome Study in PN Research-Important Aspects (see Figs. 4.3 and 4.4, Box 2).
4.4.1 Setting Standards in the Microbiome Field -- 4.4.2 Visualizing Methods in Microbiome Research -- 4.5 From the Clinical Trial to the Personal Recommendation: Putting the Individual Pieces of the Puzzle Together -- 4.6 Conclusion -- References -- 5 Personalized Nutrition for Healthy Aging, A Review -- 5.1 Healthy Aging -- 5.1.1 Genetics and Healthy Aging -- 5.1.2 Epigenetics and Healthy Aging -- 5.1.3 Histones and Healthy Aging -- 5.1.4 Noncoding RNAs (NcRNAs) and Aging -- 5.1.5 Aging of the Immune System (I.S.) and Epigenetics -- 5.1.6 Neurodegenerative Diseases, Aging, and Epigenetics -- 5.1.7 Microbiota and Healthy Aging -- 5.1.8 Individual-Specific Aging -- 5.2 Ways to Personalization -- 5.2.1 Missing Heritability -- 5.2.2 Markers Enable a Personalized Pre- and Intervention -- 5.3 Developments of Precision Medicine -- 5.4 Development of Personalized Precision Nutrition -- 5.4.1 Personalized Nutrition and Nutriepigenetics -- 5.4.2 Personalized Nutrition and Gene Expression -- 5.4.3 Personalized Nutrition and Microbiota-Epigenetic Interactions -- 5.5 Omics Approaches and Data Integration -- 5.5.1 Translation of Personalized Precision Nutrition into Praxis -- 5.5.2 Personalization or Stratification, Metabotypes -- 5.5.3 Personalized Precision Nutrition and Consumer Aspects -- 5.5.4 Consumer Supporting Organizations in Between Multiple Interests, Discussion -- References -- 6 Precise Nutrition and Metabolic Syndrome, Remodeling the Microbiome with Polyphenols, Probiotics, and Postbiotics -- 6.1 Introduction -- 6.2 Metabolic Syndrome-Definition, Prevalence, and Pathophysiology -- 6.3 The Microbiome-Composition, Establishment, and Functions -- 6.4 Role of Microbiome in Development of Metabolic Syndrome -- 6.5 Precision Nutrition-Gut Microbiota as a Target for Metabolic Syndrome Treatment -- 6.5.1 Probiotics -- 6.5.2 Postbiotics -- 6.5.3 Polyphenols. 6.6 Conclusion -- Literatures -- 7 Precision Nutrition and Metabolomics, a Model of Alzheimer's Disease -- 7.1 Introduction -- 7.2 Metabolomics and the -Omics Cascade -- 7.3 How Metabolomics Provides Actionable Insights into Disease Pathophysiology -- 7.4 Western-Style Diet, Metabolism, and the Epidemiology of Chronic Disease -- 7.5 Western-Style Diet, the Association with Intracellular Malnutrition, and Nutritional Interventions in Alzheimer's Disease -- 7.6 A Metabolic Model of Alzheimer's Disease, and Its Relationship with Nutritional and Microbiome-Related Factors -- 7.6.1 Lipid Metabolism -- 7.6.2 Glucose Homeostasis and Alterations in Energy Supply -- 7.6.3 Bile Acid Metabolism -- 7.6.4 The Metabolic Model of Alzheimer's Disease (AD) -- 7.7 Conclusion -- References -- 8 Precision Nutrition and Cognitive Decline -- 8.1 Introduction -- 8.2 Nutrients and Dietary Patterns -- 8.2.1 Antioxidants -- 8.2.2 Vitamins -- 8.2.3 Omega-3 Fatty Acids -- 8.2.4 Dietary Patterns -- 8.3 Individualized Response to Diet -- 8.3.1 Human Genome -- 8.3.2 Epigenome -- 8.3.3 Microbiome -- 8.4 Risk Factors for Dementia -- 8.5 Challenges and Future Directions -- References -- 9 Algorithms for and Challenges in the Analysis of Markers in Personalized Health Care -- 9.1 Introduction -- 9.2 Supervised Learning -- 9.2.1 Basic Definitions and the Learning Task -- 9.2.2 Loss Functions -- 9.2.3 Errors -- 9.2.4 Model Selection, Model Assessment, and Datasets -- 9.2.5 Learnability and Data -- 9.2.6 Bias and Variance -- 9.3 Algorithms -- 9.3.1 KNN -- 9.3.2 Linear Regression -- 9.3.3 Logistic Regression -- 9.3.4 Artificial Neural Networks -- 9.3.5 Naive Bayes Classifiers -- 9.3.6 Decision Trees and Random Forests -- 9.4 The Challenges -- 9.4.1 Overfitting -- 9.4.2 (Epi-)genetic Problems -- 9.4.3 A Numerical Example -- 9.5 Quality Metrics. 9.5.1 True and False Positives and Negatives -- 9.5.2 Positive and Negative Rates -- 9.5.3 Predictive Values Etc. -- 9.5.4 Prevalence, Accuracy, and Informedness -- 9.5.5 Weighted Informedness or Weighted Youden's Index -- 9.5.6 Confusion Matrix -- 9.5.7 A Numerical Example -- 9.6 Probably Approximately Correct -- 9.7 Conclusions -- 10 Precise Nutrition and Functional Foods -- 10.1 Novel Food, Food Supplements, Nutraceuticals, Phytoceuticals, Medicinal Foods -- 10.2 Fasting, Caloric Restriction (CR) -- 10.3 Modulating the Diet-Gut Microbiome Interplay -- 10.4 Probiotics -- 10.5 Prebiotics -- 10.6 Nutraceuticals -- 10.7 Medical Foods -- 10.8 Mechanistic Aspects of Special Foods -- 10.8.1 Epigenetic Active Foods -- 10.8.2 Sirtuin Activation by "Sirtfoods" -- 10.9 Senolytic Foods -- 10.9.1 Fasting Mimetics -- 10.10 Personalization, Discussion -- References -- 11 Precision Nutrition from a Practical Clinical View, Case Study -- 11.1 Introduction -- 11.2 Chances of Diagnostics and Markers -- 11.3 Case Study -- 11.4 Conclusion -- 12 Translational Aspects in Precision Nutrition, Personalization, Biomarkers and Healthy Aging -- 12.1 Boom in Medical Self-tests-Since Corona Pandemic -- 12.2 From One Fits-All Recommendations to Personalized Tests -- 12.3 Nutrigenetics -- 12.4 Impact of Genetic Lifestyle Tests -- 12.5 Compliance of Lifestyle Change -- 12.6 Nutrigeneomics -- 12.7 Personalized Epigenetic Testing -- 12.8 Personalized Microbiota Analysis -- 12.9 Legal Responsibility -- 12.10 Validation of Study Results and Generation of Limit Values -- 12.11 Conclusion -- Appendix -- References. |
Record Nr. | UNINA-9910629286503321 |
Haslberger Alexander G.
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Cham, Switzerland : , : Springer, , [2022] | ||
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Lo trovi qui: Univ. Federico II | ||
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Agricultural, Forestry and Bioindustry Biotechnology and Biodiscovery [[electronic resource] /] / edited by Pablo A. Chong, David J. Newman, Douglas A. Steinmacher |
Edizione | [1st ed. 2020.] |
Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2020 |
Descrizione fisica | 1 online resource (460 pages) |
Disciplina | 333.95 |
Soggetto topico |
Biodiversity
Agriculture Forestry Plant breeding Plant pathology Natural resources Plant Breeding/Biotechnology Plant Pathology Natural Resources Biotecnologia agrícola Genètica vegetal Protecció ambiental Nutrició |
Soggetto genere / forma | Llibres electrònics |
ISBN | 3-030-51358-0 |
Formato | Materiale a stampa ![]() |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto | Genetically modified organisms (GMOs) impact and current status in Latin America: technological sovereignty or dependence? -- New biotechnology promising approaches for disease control on bananas and plantains -- Complementation of bananas conventional breeding programs through biotechnological genetic improvement -- The stress as inducer of heritable changes in micropropagated banana: the hypothesis of cytokinin accumulation -- Somatic embryogenesis for clonal propagation and associated molecular studies in cacao (Theobroma cacao L.) -- Use of biotechnology in Forestry breeding programs for natural resources and biodiversity conservation; Creating super trees for the future -- Stress modulation in Pinus spp. Somatic embryogenesis as model for climate change mitigation; Stress is not always a problem -- A Protective Role for Accumulated Dry Matter Reserves in Seeds During Desiccation: Implications for Conservation -- Biodiversity in Ecuador and its immense potential for agricultural pest control -- Native biodiversity: a strategic resource to accelerate bioeconomy development in Latin America and the Caribbean -- Low cost crop waste biosorbent technology for removing toxic and pollutants from wastewater -- The status of plant and plant-microbe interactions related to medicinal agents -- Bringing new function to packaging materials by agricultural byproducts -- Use of banana crop wastes to develop products in the aquaculture and plastic sectors -- Use of agroindustrial biomass for biofuels, enzymes discovery and production -- Temperature Profiles during the Fermentation of Cacao ‘Nacional’ to understand chocolate quality -- Ethno Phytopharmacology. Product validation process based on traditional knowledge of medicinal plants -- Biological control as a key tool for the management of invasive species in Latin America and the Caribbean -- Current research on Andean fruit crop diseases -- Biotechnological tools for the development of Foc TR4-resistant or tolerant Musa spp. Cultivars -- Integrated pest management of whitefly crop-free periods can reduce the Begomovirus transmission in tomato. |
Record Nr. | UNINA-9910416096703321 |
Cham : , : Springer International Publishing : , : Imprint : Springer, , 2020 | ||
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Lo trovi qui: Univ. Federico II | ||
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The American journal of clinical nutrition |
Pubbl/distr/stampa | Bethesda, Md, : American Society for Nutrition, with the assistance of Highwire Press |
Descrizione fisica | 1 online resource |
Disciplina | 612.3 |
Soggetto topico |
Nutrition
Diet in disease Régimes alimentaires Nutrició - Revistes Dietètica - Revistes Dietoteràpia - Revistes Nutrició Dieta Diet Nutritional Physiological Phenomena |
Soggetto genere / forma |
Periodical
Periodicals. Revistes electròniques. |
ISSN | 1938-3207 |
Formato | Materiale a stampa ![]() |
Livello bibliografico | Periodico |
Lingua di pubblicazione | eng |
Record Nr. | UNINA-9910131793103321 |
Bethesda, Md, : American Society for Nutrition, with the assistance of Highwire Press | ||
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Lo trovi qui: Univ. Federico II | ||
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The American journal of clinical nutrition |
Pubbl/distr/stampa | Bethesda, Md, : American Society for Nutrition, with the assistance of Highwire Press |
Descrizione fisica | 1 online resource |
Disciplina | 612.3 |
Soggetto topico |
Nutrition
Diet in disease Régimes alimentaires Nutrició - Revistes Dietètica - Revistes Dietoteràpia - Revistes Nutrició Dieta Diet Nutritional Physiological Phenomena |
Soggetto genere / forma |
Periodical
Periodicals. Revistes electròniques. |
ISSN | 1938-3207 |
Formato | Materiale a stampa ![]() |
Livello bibliografico | Periodico |
Lingua di pubblicazione | eng |
Record Nr. | UNISA-996203646303316 |
Bethesda, Md, : American Society for Nutrition, with the assistance of Highwire Press | ||
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Lo trovi qui: Univ. di Salerno | ||
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Amino Acids in Nutrition and Health [[electronic resource] ] : Amino acids in systems function and health / / edited by Guoyao Wu |
Edizione | [1st ed. 2020.] |
Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2020 |
Descrizione fisica | 1 online resource (VI, 220 p. 36 illus., 10 illus. in color.) |
Disciplina | 574.192 |
Collana | Advances in Experimental Medicine and Biology |
Soggetto topico |
Immunology
Medicine Cell biology Biochemistry Nutrition Medicine/Public Health, general Cell Biology Biochemistry, general Nutrition Nutrició Salut Aminoàcids Sistema immunitari |
Soggetto genere / forma | Llibres electrònics |
ISBN | 3-030-45328-6 |
Formato | Materiale a stampa ![]() |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto | Preface -- Amino acids in intestinal physiology and health -- Amino acid metabolism in the liver: nutritional and physiological significance -- Amino acids in circulatory function and health -- Epithelial dysfunction in lung diseases: effects of amino acids and potential mechanisms -- Amino acid metabolism in the kidneys: nutritional and physiological significance -- Amino acids in health and endocrine function -- Amino Acids in Reproductive Nutrition and Health -- Impacts of amino acids on the intestinal defensive system -- Maternal nutrient restriction and skeletal muscle development: Consequences for postnatal health -- Metabolism of amino acids in the brain and their roles in regulating food intake -- Metabolism and functions of amino acids in the skin -- Metabolism and functions of amino acids in sense organs. . |
Record Nr. | UNINA-9910416102703321 |
Cham : , : Springer International Publishing : , : Imprint : Springer, , 2020 | ||
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Lo trovi qui: Univ. Federico II | ||
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Aquatic animal nutrition : organic macro- and micro-nutrients / / Christian E. W. Steinberg |
Autore | Steinberg Christian |
Pubbl/distr/stampa | Cham, Switzerland : , : Springer International Publishing, , [2022] |
Descrizione fisica | 1 online resource (1082 pages) |
Disciplina | 591.76 |
Soggetto topico |
Aquatic animals - Behavior
Aquatic animals - Sense organs Fauna aquàtica Nutrició |
Soggetto genere / forma | Llibres electrònics |
ISBN |
9783030872274
9783030872267 |
Formato | Materiale a stampa ![]() |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Record Nr. | UNINA-9910523884303321 |
Steinberg Christian
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Cham, Switzerland : , : Springer International Publishing, , [2022] | ||
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Lo trovi qui: Univ. Federico II | ||
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Biomarkers in nutrition / / Vinood B. Patel and Victor R. Preedy |
Autore | Patel Vinood B. |
Pubbl/distr/stampa | Cham, Switzerland : , : Springer International Publishing, , [2022] |
Descrizione fisica | 1 online resource (1173 pages) |
Disciplina | 610.28 |
Collana | Biomarkers in Disease |
Soggetto topico |
Biochemical markers
Biochemical markers - Evaluation Marcadors bioquímics Nutrició |
Soggetto genere / forma | Llibres electrònics |
ISBN | 3-031-07389-4 |
Formato | Materiale a stampa ![]() |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Record Nr. | UNINA-9910617306803321 |
Patel Vinood B.
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Cham, Switzerland : , : Springer International Publishing, , [2022] | ||
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Lo trovi qui: Univ. Federico II | ||
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Coconut Water [[electronic resource] ] : A Promising Natural Health Drink-Distribution, Processing and Nutritional Benefits / / by P. Rethinam, V. Krishnakumar |
Autore | Rethinam P. |
Edizione | [1st ed. 2022.] |
Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2022 |
Descrizione fisica | 1 online resource (531 pages) |
Disciplina | 615.854 |
Soggetto topico |
Food science
Food - Analysis Chemistry Nutrition Food - Safety measures Food Science Food Chemistry Food Safety Coco Nutrició |
Soggetto genere / forma | Llibres electrònics |
ISBN | 3-031-10713-6 |
Formato | Materiale a stampa ![]() |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto | Chapter 1 Introduction -- Chapter 2.Global Scenario of Coconut and Coconut Water -- Chapter 3 Tender Coconut Varieties -- 4 Composition, Properties and Reactions of Coconut Water -- Chapter 5 Processing of Coconut Water -- Chapter 6 Packing, Storage and Transport of Coconut Water -- Chapter 7 Standards of Coconut Water -- Chapter 8 Value addition in Coconut Water -- Chapter 9 Health Benefits of Coconut Water -- Chapter 10 Contamination and Adulteration of Coconut Water -- Chapter 11 Patents Granted on Coconut Water -- Chapter 12 Coconut Water- The Way Forward. |
Record Nr. | UNINA-9910617306403321 |
Rethinam P.
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Cham : , : Springer International Publishing : , : Imprint : Springer, , 2022 | ||
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Lo trovi qui: Univ. Federico II | ||
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Dietary phytochemicals : a source of novel bioactive compounds for the treatment of obesity, cancer and diabetes / / Chukwuebuka Egbuna, Sadia Hassan, editors |
Pubbl/distr/stampa | Cham, Switzerland : , : Springer, , [2021] |
Descrizione fisica | 1 online resource (262 pages) |
Disciplina | 615.321 |
Soggetto topico |
Phytochemicals - Health aspects
Fitoquímica Nutrició Biotransformació (Metabolisme) Càncer Obesitat Diabetis |
Soggetto genere / forma | Llibres electrònics |
ISBN | 3-030-72999-0 |
Formato | Materiale a stampa ![]() |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto |
Intro -- Preface -- Contents -- Etiology of Obesity, Cancer, and Diabetes -- 1 Introduction -- 2 Obesity -- 2.1 Etiology of Obesity -- 2.2 Biological Factors -- 2.2.1 Genetics -- Monogenic Obesity -- Syndromic Obesity -- Polygenic Obesity -- 2.2.2 Brain-gut Axis -- 2.2.3 Prenatal Determinants -- 2.2.4 Pregnancy -- 2.2.5 Menopause -- 2.2.6 Physical Disability -- 2.2.7 Gut Microbiome -- 2.3 Environmental Factors -- 2.3.1 Obesogenic Environment -- 2.3.2 Socio-Economic Factors -- 2.3.3 Environmental Chemicals and Obesity -- 2.4 Behavioral Factors -- 2.4.1 Increased Calorie Intake and Eating Habits -- 2.4.2 Sedentary Lifestyle and Less Physical Activity -- 2.4.3 Insufficient Sleep -- 2.4.4 Quitting Smoking -- 3 Cancer -- 3.1 Major Types of Cancer -- 3.2 Causes of Cancer -- 3.2.1 Diet and Physical Activity -- 3.2.2 Use of Addictive Substances -- 3.2.3 Sex and Reproductive Health -- 3.2.4 Environmental Factors -- 3.2.5 Genetics -- 4 Diabetes Mellitus -- 4.1 Causes of Type 1 Diabetes Mellitus -- 4.1.1 Genetic Susceptibility Factors -- 4.1.2 Virus-Related Contagions -- 4.1.3 Role of Environment -- 4.2 Etiology of Type 2 Diabetes Mellitus -- 5 Conclusion -- References -- Pathophysiology of Obesity and Diabetes -- 1 Introduction -- 2 Obesity and Body Mass Index -- 3 Pathophysiology of Obesity -- 3.1 Development of Fat Cells -- 3.2 Fat Cell Metabolism -- 3.3 Oxidative Stress -- 3.4 Weight Stigma -- 4 Role of Different Factors in the Pathophysiology of Obesity -- 4.1 Pathophysiology of Obesity and the Role of Autonomic Nervous System -- 4.2 Osteopontin and Obesity -- 4.3 Obesity and Renal Disease -- 5 Maternal Obesity -- 6 Potential Role of Gut Inflammation in Disease Development -- 7 Childhood Obesity -- 8 Pathophysiology of Diabetes -- 8.1 Etiology of Diabetes -- 8.2 Role of Genetics in Development of T2DM.
8.3 Role of Environmental Determinants in the Development of T2DM -- 8.4 Insulin Resistance -- 8.5 The Role of Glucagon -- 8.6 Somatostatin -- 9 Conclusion -- References -- Pathophysiology of Obesity and Cancer: Drugs and Signaling Targets -- 1 Introduction -- 2 Pathophysiology of Obesity and Cancer -- 3 History of Anti-obesity Drugs -- 4 How to Treat Obesity? -- 5 Different Targets in Brain to Treat Obesity -- 5.1 Serotoninergic System -- 5.2 Noradrenergic System -- 5.3 Dopaminergic System -- 6 Link Between Obesity and Cancer -- 7 Drugs Targeting Cancer Cells -- 8 Drugs Targeting the Tumor Microenvironment's Cellular and Molecular Components -- 9 Changes in the Pharmacokinetics -- 10 Changes in Microbiota -- 11 Combination Therapy -- 12 Conclusion -- References -- Peptides Involved in Body Weight Regulation -- 1 Introduction -- 2 Appetite, Food Intake, and Obesity -- 3 Peptides and Body Weight -- 3.1 Effects of Hormonal Peptides -- 3.1.1 Orexigenic Peptides -- 3.1.2 Anorexigenic Peptides -- 3.1.3 Effects of Hypothalamic Peptides -- 3.2 Bioactive Peptides and Body Weight -- 4 Conclusion -- References -- Insulin Resistance: A Link Between Obesity and Cancer -- 1 Introduction -- 2 Obesity and Cancer -- 3 Diabetes and Cancer -- 4 Obesity and Diabetes -- 5 Mechanism Linking Insulin Resistance to Obesity and Cancer -- 6 Drugs to Treat Insulin Resistance -- 6.1 Metformin -- 6.2 Thiazolidinediones -- 6.3 Insulin Analogues -- 7 Challenges in Prevention and Treatment -- 8 Conclusion -- References -- Role of Cytoskeletal Protein, Actin in Various Diseases -- 1 Introduction -- 2 Microfilaments or Actin Filaments -- 2.1 Role in Cancer Metastasis and Tumor Angiogenesis -- 2.2 Role in Cytokinesis -- 2.3 Role in Cellular Signaling and Transport -- 2.4 Role in Immunodeficiency -- 2.5 Role in Fertilization of Eggs -- 2.6 Role in Neuronal Plasticity. 2.7 Role in Neurodegenerative Diseases -- 2.8 Role in Epigenetic Control -- 2.9 Role in Muscle Contraction -- 3 Conclusions -- References -- Diabetes Mellitus and it Management with Plant-Based Therapy -- 1 Introduction -- 2 Classification of Diabetes -- 2.1 Type I Diabetes Mellitus (T1DM) -- 2.2 Type II Diabetes Mellitus (T2DM) -- 2.3 Gestational DM (GDM) -- 3 Risk Factors of Diabetes -- 4 Pathophysiology -- 5 Screening and Diagnosis -- 6 Management -- 6.1 Through Lifestyle and Diet Modification -- 6.2 Pharmacological Agents -- 6.3 Plant Based Therapy -- 6.3.1 Mechanisms Underlying Herbal Anti-Diabetic Therapies -- 6.3.2 Classification of Plant-Based Anti-Diabetics -- 7 Conclusion -- References -- Fruits and Vegetables as Sources of Functional Phytochemicals for the Prevention and Management of Obesity, Diabetes, and Cancer -- 1 Introduction -- 2 Classification of Phytochemicals -- 2.1 Polyphenols -- 2.2 Terpenoids -- 2.3 Thiols -- 3 Health Benefits and Nutritional Value of Certain Fruits and Vegetables -- 3.1 Tomatoes -- 3.2 Grapes and Berries -- 3.3 Nuts -- 3.4 Citrus -- 3.5 Brassica Vegetables -- 3.6 Mushrooms -- 3.7 Kiwi -- 3.8 Cladodes -- 3.9 Carrots -- 3.10 Potatoes -- 3.11 Onion and Garlic -- 4 The Effect of Consuming Fruits and Vegetables on Some Diseases -- 4.1 Cancer -- 4.2 Obesity -- 4.3 Diabetes -- 5 Conclusion -- References -- Spices for Diabetes, Cancer and Obesity Treatment -- 1 Introduction -- 2 Anti-diabetic Effect of Spices -- 2.1 Fenugreek -- 2.2 Cinnamon -- 2.3 Garlic and Onion -- 2.4 Turmeric -- 2.5 Cumin Seeds -- 2.6 Ginger -- 3 Spices in the Treatment of Cancer -- 3.1 Basil -- 3.2 Caraway -- 3.3 Cardamom -- 3.4 Rosemary -- 3.5 Cumin -- 3.6 Turmeric -- 3.7 Garlic -- 3.8 Black Pepper -- 3.9 Red Chili -- 3.10 Ginger -- 3.11 Saffron -- 4 Spices in the Treatment of Obesity -- 4.1 Ginger -- 4.2 Turmeric -- 4.3 Garlic. 4.4 Red Pepper -- 5 Conclusion -- References -- MicroRNAs as Targets of Dietary Phytochemicals in Obesity and Cancer -- 1 Introduction -- 2 Phytochemical Modulated miRNAs and Its Role in Obesity -- 3 MicroRNAs as Phytochemicals Targets in Carcinogenesis -- 4 Dietary Phytochemicals and miRNA -- 4.1 Resveratrol -- 4.2 Genistein -- 4.3 Conjugated Linoleic Acids -- 4.4 Cinnamic Acid and Cinnamaldehyde -- 4.5 Ajoene -- 4.6 Curcumin -- 4.7 Epigallocatechin-3-Gallate -- 4.8 Quercetin -- 5 Conclusion -- References -- Natural Phenolic Compounds as Anti-obesity and Anti-cardiovascular Disease Agent -- 1 Introduction -- 2 Effects of Natural Phenolic Compounds on Oil and Fat Metabolism -- 3 Binding Bile Salt to Inhibit Emulsification of Lipids -- 3.1 In Vitro Studies -- 4 Pancreatic Lipase Inhibition -- 4.1 In Vitro Studies -- 4.2 In Silico Modeling Studies -- 4.3 Increase Fecal Lipid Excretion -- 4.4 Animal Models -- 4.5 Clinical Research -- 5 Gut Microbiota as Potential Targets -- 6 Reduction of Lipogenesis and Inflammation in Adipose Tissue and Liver -- 6.1 In Vitro Studies by Cell Models -- 6.2 Animal Models -- 7 Suppression of Lipogenic Enzyme Fatty Acid Synthase (FAS) in Cell -- 7.1 Cell Model -- 7.2 Animal Models -- 8 Increase of Lipolysis in Cell -- 9 Inhibition of Adipocyte Differentiation and Growth -- 10 Anti-atherosclerosis by Natural Phenolic Compounds -- 11 Conclusion -- References -- Harnessing the Potential of Phytochemicals for Breast Cancer Treatment -- 1 Introduction -- 2 Statistical Evidence Including the Indian Scenario -- 3 Current Treatments Strategies for Breast Cancer -- 3.1 Chemotherapy -- 3.2 Surgery -- 3.3 Gene Therapy -- 3.4 Oncogenes Inactivation -- 3.5 Augmentation of Tumor Suppresser Genes -- 3.5.1 BRCA1 and BRCA2 -- 3.5.2 Androgen Receptor -- 3.5.3 Immunomodulation -- 3.5.4 Endocrine (Antihormonal) Treatment. 3.5.5 Inclination Towards Phytochemicals -- 4 Phytochemicals for Breast Cancer Therapy -- 4.1 Plumbagin -- 4.2 Apigenin -- 4.3 Isothiocyanate -- 4.4 Quercetin -- 4.5 Curcumin -- 4.6 Catechins -- 4.7 Lycopene -- 4.8 Hesperidin -- 4.9 Anthocyanin -- 4.10 Colchicine Alkaloid -- 4.11 Polyphyllin D -- 4.12 Genistein -- 4.13 Resveratrol -- 4.14 Berberine -- 5 Pharmaceutical Compounding of Phytochemicals -- 6 Conclusion -- References -- Index. |
Record Nr. | UNINA-9910495214003321 |
Cham, Switzerland : , : Springer, , [2021] | ||
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Lo trovi qui: Univ. Federico II | ||
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