Pubbl/distr/stampa	Hoboken, New Jersey : , : Wiley, , [2014]
Descrizione fisica	1 online resource (567 p.)
Disciplina	572/.6
Altri autori (Persone)	OrengoChristine A. <1955-> BatemanAlex <1972->
Collana	Wiley series in protein and peptide science
Soggetto topico	Proteins Proteomics Molecular biology - Data processing Bioinformatics
ISBN	1-118-74281-8 1-118-74308-3 1-118-74285-0
Classificazione	COM082000
Formato	Materiale a stampa
Livello bibliografico	Monografia
Lingua di pubblicazione	eng
Nota di contenuto	Cover; Title Page; Contents; Introduction; Contributors; Part I Concepts Underlying Protein Family Classification; Chapter 1 Automated Sequence-Based Approaches for Identifying Domain Families; 1.1 Introduction; 1.2 Motivation Behind Automated Classification; 1.3 Clustering the Sequence Space Graph; 1.4 Historical Overview of Sequence Clustering Algorithms; 1.5 Related Methods; 1.6 Quality Assessment; 1.7 ADDA-The Automatic Domain Delineation Algorithm; 1.8 Results; 1.9 Conclusions; References; Chapter 2 Sequence Classification of Protein Families: Pfam and other Resources; 2.1 Introduction 2.2 Pfam2.3 Smart, Prosite Profiles, CDD and Tigrfams; 2.4 Philosophy of Pfam; 2.5 HMMER3 and Jackhmmer; 2.6 Sources of New Families; 2.7 Annotation of Families; 2.8 The InterPro Collection; 2.9 The Future of Sequence Classification; References; Chapter 3 Classifying Proteins into Domain Structure Families; 3.1 Introduction; 3.2 The Classification Hierarchies Adopted by Scop and Cath; 3.3 Challenges in Identifying Domains in Proteins; 3.4 Structure-Based Approaches for Identifying Related Folds and Homologs; 3.5 Approaches to Structure Comparison; 3.6 The DALI Algorithm 3.7 The SSAP Algorithm Used for Fold Recognition in CATH3.8 Fast Approximate Methods Used to Recognize Folds in CATH; 3.9 Measuring Structural Similarity; 3.10 Multiple Structure Alignment; 3.11 Classification Protocols; 3.12 Population of the Hierarchy; 3.13 Comparisons Between Scop and CATH; 3.14 Hierarchical Classifications Versus Structural Continuum; 3.15 Websites; References; Chapter 4 Structural Annotations of Genomes with Superfamily and Gene3D; 4.1 Introduction; 4.2 The Importance of Being High Throughput; 4.3 The Use of Structural Information; 4.4 Applications; 4.5 History 4.6 Technology4.7 Hidden Markov Models; 4.8 Building Models; 4.9 Domain Annotations; 4.10 High Throughput Computation; 4.11 Development of New Bioinformatics Algorithms; 4.12 Genomes; 4.13 e-Value Scores; 4.14 Other Sequence Sets; 4.15 Data Access; 4.16 Analysis Tools; 4.17 Conclusion; References; Chapter 5 Phylogenomic Databases and Orthology Prediction; 5.1 The Evolution of Novel Functions and Structures in Gene Families; 5.2 Homologs, Orthologs, Paralogs, and Other Evolutionary Terms; 5.3 The Standard Functional Annotation Protocol; 5.4 Orthology Identification Methods and Databases 5.5 Challenges in Phylogenetic Methods of Ortholog Identification5.6 Evaluating Ortholog Identification Methods; 5.7 Orthology Databases; 5.8 Phylogenomic Databases; 5.9 PhyloFacts; 5.10 Subfamily Classification in Phylofacts; 5.11 PhyloFacts 3.0; 5.12 PhylomeDB; 5.13 Panther; 5.14 Structural Phylogenomics: Improved Functional Annotation Through Integration of Information from Structure and Evolution; 5.15 Specific Issues in Phylogenomic Pipelines; 5.16 Improving Functional Inference using Information from Protein Structure; 5.17 Example Case Studies; 5.18 Review of Key Points; References Part II In-Depth Reviews of Protein Families
Record Nr.	UNINA-9910139014903321

Autore	Moses Alan
Pubbl/distr/stampa	Boca Raton : , : CRC Press, , [2017]
Descrizione fisica	1 online resource
Disciplina	572.8
Collana	Chapman & Hall/CRC mathematical and computational biology series
Soggetto topico	Molecular biology - Statistical methods Molecular biology - Data processing
ISBN	1-4822-5862-5 1-315-37226-6 1-4822-5860-9
Formato	Materiale a stampa
Livello bibliografico	Monografia
Lingua di pubblicazione	eng
Nota di contenuto	section 1. Overview -- section 2. Clustering -- section 3. Regression -- section 4. Classification.
Record Nr.	UNINA-9910162857403321

Edizione	[1st ed. 2005.]
Pubbl/distr/stampa	Berlin, : Springer, c2005
Descrizione fisica	1 online resource (XII, 112 p.)
Disciplina	572.80285
Altri autori (Persone)	PriamiCorrado
Collana	Lecture notes in computer science. Lecture notes in bioinformatics
Soggetto topico	Molecular biology - Data processing Bioinformatics Proteomics
Soggetto non controllato	Bioinformatics Molecular Biology Science
Formato	Materiale a stampa
Livello bibliografico	Monografia
Lingua di pubblicazione	eng
Nota di contenuto	Accessible Protein Interaction Data for Network Modeling. Structure of the Information and Available Repositories -- Early Systems Biology and Prebiotic Networks -- Virtualization in Systems Biology: Metamodels and Modeling Languages for Semantic Data Integration -- Genome Size and Numbers of Biological Functions -- Operational Patterns in Beta-Binders -- Discrete Event Multi-level Models for Systems Biology -- A New Time-Dependent Complexity Reduction Method for Biochemical Systems.
Record Nr.	UNISA-996465972603316

Edizione	[1st ed. 2008.]
Pubbl/distr/stampa	Berlin, Germany : , : Springer, , [2008]
Descrizione fisica	1 online resource (VII, 153 p.)
Disciplina	572.80285
Collana	Transactions on Computational Systems Biology
Soggetto topico	Bioinformatics Proteomics Molecular biology - Data processing
Soggetto non controllato	Molecular Biology Bioinformatics Science
ISBN	3-540-88765-2
Formato	Materiale a stampa
Livello bibliografico	Monografia
Lingua di pubblicazione	eng
Nota di contenuto	A Quantitative bgl Operon Model for E. coli Requires BglF Conformational Change for Sugar Transport -- Punctuated Equilibrium in Statistical Models of Generalized Coevolutionary Resilience: How Sudden Ecosystem Transitions Can Entrain Both Phenotype Expression and Darwinian Selection -- Stochastic Calculus of Looping Sequences for the Modelling and Simulation of Cellular Pathways -- The BlenX Language with Biological Transactions.
Record Nr.	UNINA-9910484356303321

Edizione	[1st ed. 2007.]
Pubbl/distr/stampa	Berlin ; ; Heidelberg : , : Springer-Verlag, , [2007]
Descrizione fisica	1 online resource (VII, 108 p.)
Disciplina	572.8
Collana	Lecture notes in computer science Journal subline
Soggetto topico	Molecular biology - Data processing Bioinformatics Proteomics
ISBN	3-540-76639-1
Formato	Materiale a stampa
Livello bibliografico	Monografia
Lingua di pubblicazione	eng
Nota di contenuto	Bio-inspired Network-Centric Operation and Control for Sensor/Actuator Networks -- A Computationally Fast and Parametric Model to Estimate Protein-Ligand Docking Time for Stochastic Event Based Simulation -- Equation-Based Congestion Control in the Internet Biologic Environment -- Computational Thinking in Biology -- End-to-End Information Management for Systems Biology -- On Differentiation and Homeostatic Behaviours of Boolean Dynamical Systems.
Altri titoli varianti	Transactions on computational systems biology 8 Transactions on computational systems biology eight
Record Nr.	UNINA-9910483995503321