Cycloadditions in Bioorthogonal Chemistry [[electronic resource] /] / edited by Milan Vrabel, Thomas Carell |
Edizione | [1st ed. 2016.] |
Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2016 |
Descrizione fisica | 1 online resource (V, 157 p. 88 illus., 42 illus. in color.) |
Disciplina | 547 |
Collana | Topics in Current Chemistry Collections |
Soggetto topico |
Bioorganic chemistry
Medicinal chemistry Genetic engineering Bioorganic Chemistry Medicinal Chemistry Genetic Engineering |
ISBN | 3-319-29686-8 |
Formato | Materiale a stampa ![]() |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto | Bioorthogonal Chemistry: Introduction and Overview -- Transition Metal Catalyzed Bioorthogonal Cycloaddition Reactions -- Strain-Promoted 1,3-Dipolar Cycloaddition of Cycloalkynes and Organic Azides -- Photo-triggered Click Chemistry for Biological Applications -- Inverse Electron-Demand Diels-Alder Bioorthogonal Reactions -- Cycloadditions for Studying Nucleic Acids. |
Record Nr. | UNINA-9910254026303321 |
Cham : , : Springer International Publishing : , : Imprint : Springer, , 2016 | ||
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Lo trovi qui: Univ. Federico II | ||
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Designing Receptors for the Next Generation of Biosensors [[electronic resource] /] / edited by Sergey A. Piletsky, Michael J. Whitcombe |
Edizione | [1st ed. 2013.] |
Pubbl/distr/stampa | Berlin, Heidelberg : , : Springer Berlin Heidelberg : , : Imprint : Springer, , 2013 |
Descrizione fisica | 1 online resource (270 p.) |
Disciplina | 610/.28 |
Collana | Springer Series on Chemical Sensors and Biosensors, Methods and Applications |
Soggetto topico |
Chemical engineering
Analytical chemistry Medicinal chemistry Bioorganic chemistry Biomedical engineering Biomaterials Industrial Chemistry/Chemical Engineering Analytical Chemistry Medicinal Chemistry Bioorganic Chemistry Biomedical Engineering and Bioengineering |
ISBN |
1-283-64063-5
3-642-32329-4 |
Formato | Materiale a stampa ![]() |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto | Multichannel Sensors Based on Biphenyl and Cyclohexane Conformational Changes -- Learning from Proteins and Drugs: Receptors that Mimic Biomedically Important Binding Motifs -- Molecular Recognition of Nucleotides -- Molecular Recognition of Oligopeptides and Protein Surfaces -- Antimicrobial Peptides for Detection and Diagnostic Assays -- Plastic Antibodies -- Computational Approaches in the Design of Synthetic Receptors -- MIP Sensors on the Way to Real-World Applications -- Molecularly Imprinted Au Nanoparticle Composites for Selective Sensing Applications -- Design and Development of in vivo Sensor Systems: The Long and Tortured Road to a Self-Contained, Implantable Glucose Sensor for Diabetes Management -- Evolving Trends in Transition Metal-Modified Receptor Design and Function. |
Record Nr. | UNINA-9910437799503321 |
Berlin, Heidelberg : , : Springer Berlin Heidelberg : , : Imprint : Springer, , 2013 | ||
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Lo trovi qui: Univ. Federico II | ||
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Development of Chemistry-Based Screening Platform for Access to Mirror-Image Library of Natural Products [[electronic resource] /] / by Taro Noguchi |
Autore | Noguchi Taro |
Edizione | [1st ed. 2018.] |
Pubbl/distr/stampa | Singapore : , : Springer Singapore : , : Imprint : Springer, , 2018 |
Descrizione fisica | 1 online resource (XIV, 80 p. 46 illus., 18 illus. in color.) |
Disciplina | 572.36 |
Collana | Springer Theses, Recognizing Outstanding Ph.D. Research |
Soggetto topico |
Medicinal chemistry
Organic chemistry Pharmaceutical technology Medicinal Chemistry Organic Chemistry Pharmaceutical Sciences/Technology |
ISBN | 981-10-6623-X |
Formato | Materiale a stampa ![]() |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto | Introduction -- Development of a Mirror-image Screening Process by Using Synthetic Proteins -- Synthesis of Grb2 SH2 Domain Proteins for Mirror-image Screening Systems -- Conclusions. |
Record Nr. | UNINA-9910298588103321 |
Noguchi Taro
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Singapore : , : Springer Singapore : , : Imprint : Springer, , 2018 | ||
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Lo trovi qui: Univ. Federico II | ||
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Development of Novel Anti-HIV Pyrimidobenzothiazine Derivatives [[electronic resource] /] / by Tsukasa Mizuhara |
Autore | Mizuhara Tsukasa |
Edizione | [1st ed. 2013.] |
Pubbl/distr/stampa | Tokyo : , : Springer Japan : , : Imprint : Springer, , 2013 |
Descrizione fisica | 1 online resource (157 p.) |
Disciplina | 616.9792 |
Collana | Springer Theses, Recognizing Outstanding Ph.D. Research |
Soggetto topico |
Organic chemistry
Pharmaceutical technology Medicinal chemistry Virology Organic Chemistry Pharmaceutical Sciences/Technology Medicinal Chemistry |
ISBN | 4-431-54445-3 |
Formato | Materiale a stampa ![]() |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto | Introduction -- Development of Divergent Synthetic Methods of Pyrimidobenzothiazine and Related Tricyclic Heterocycles -- Structure–Activity Relationship Study of PD 404182 Derivatives for the Highly Potent Anti-HIV Agents.- Design and Synthesis of Photoaffinity Probes and Their Application to Target Identification Study of PD 404182 -- Conclusion. |
Record Nr. | UNINA-9910437811403321 |
Mizuhara Tsukasa
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Tokyo : , : Springer Japan : , : Imprint : Springer, , 2013 | ||
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Lo trovi qui: Univ. Federico II | ||
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Development of Novel Hydrogen-Bond Donor Catalysts [[electronic resource] /] / by Tsubasa Inokuma |
Autore | Inokuma Tsubasa |
Edizione | [1st ed. 2013.] |
Pubbl/distr/stampa | Tokyo : , : Springer Japan : , : Imprint : Springer, , 2013 |
Descrizione fisica | 1 online resource (118 p.) |
Disciplina | 547.215 |
Collana | Springer Theses, Recognizing Outstanding Ph.D. Research |
Soggetto topico |
Organic chemistry
Medicinal chemistry Catalysis Organic Chemistry Medicinal Chemistry |
ISBN |
1-299-19802-3
4-431-54231-0 |
Formato | Materiale a stampa ![]() |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto | Introduction -- Development of HB donor catalysts -- Development and properties of novel HB donor catalysts -- Asymmetric Michael addition to alpha,beta-unsaturated imides catalyzed by HB donors -- Asymmetric Hydrazination of activated methylene compounds catalyzed by HB donors -- Development of hydroxy thiourea catalysts -- Asymmetric Michael addition of gamma-hydroxyenones and alkenylboronic acids -- Asymmetric Petasis Reaction of N-aryl-alpha-iminoamides and Alkenylboronates -- Conclusion. |
Record Nr. | UNINA-9910437807603321 |
Inokuma Tsubasa
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Tokyo : , : Springer Japan : , : Imprint : Springer, , 2013 | ||
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Lo trovi qui: Univ. Federico II | ||
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Dietary Chinese Herbs [[electronic resource] ] : Chemistry, Pharmacology and Clinical Evidence / / edited by Yanze Liu, Zhimin Wang, Junzeng Zhang |
Edizione | [1st ed. 2015.] |
Pubbl/distr/stampa | Vienna : , : Springer Vienna : , : Imprint : Springer, , 2015 |
Descrizione fisica | 1 online resource (776 p.) |
Disciplina | 615.3210951 |
Soggetto topico |
Food—Biotechnology
Clinical nutrition Plant systematics Plant taxonomy Medicinal chemistry Food Science Clinical Nutrition Plant Systematics/Taxonomy/Biogeography Medicinal Chemistry |
ISBN | 3-211-99448-3 |
Formato | Materiale a stampa ![]() |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto | Introduction -- Root, rhizome, tuber, and bulb materials -- Fruit or seed materials -- Aerial part, stem, stem bark, or leaf materials -- Flower or flower bud materials -- Multiple-part materials -- Fungi, marine algae, and other materials. |
Record Nr. | UNINA-9910298614603321 |
Vienna : , : Springer Vienna : , : Imprint : Springer, , 2015 | ||
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Lo trovi qui: Univ. Federico II | ||
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Drug Delivery Challenges and Novel Therapeutic Approaches for Retinal Diseases [[electronic resource] /] / edited by Christopher L. Cioffi |
Edizione | [1st ed. 2020.] |
Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2020 |
Descrizione fisica | 1 online resource (IX, 272 p. 1 illus.) |
Disciplina | 615.19 |
Collana | Topics in Medicinal Chemistry |
Soggetto topico |
Medicinal chemistry
Ophthalmology Pharmaceutical chemistry Medical genetics Medicinal Chemistry Pharmaceutics Clinical Genetics |
ISBN | 3-030-56619-6 |
Formato | Materiale a stampa ![]() |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto | An Overview of Retinal Diseases and Current Ocular Drug Discovery -- Ocular Pharmacokinetics and Drug Delivery Challenges -- Models of Pathologies Associated with Age-related Macular Degeneration and Their Utilities in Drug Discovery -- Recent Developments in Agents for the Treatment of Age-Related Macular Degeneration and Stargardt Disease -- Targets and Strategies toward the Development of Therapeutics for Diabetic Retinopathy and Diabetic Macular Edema -- Recent Developments for the Treatment of Glaucoma -- Emerging Gene Therapy Treatments for Retinal Degenerative Diseases. . |
Record Nr. | UNINA-9910420948603321 |
Cham : , : Springer International Publishing : , : Imprint : Springer, , 2020 | ||
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Lo trovi qui: Univ. Federico II | ||
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Drug Delivery Challenges and Novel Therapeutic Approaches for Retinal Diseases / / edited by Christopher L. Cioffi |
Edizione | [1st ed. 2020.] |
Pubbl/distr/stampa | Springer International Publishing, 2020 |
Descrizione fisica | 1 online resource (IX, 272 p. 1 illus.) |
Disciplina | 615.19 |
Collana | Topics in Medicinal Chemistry |
Soggetto topico |
Medicinal chemistry
Ophthalmology Pharmaceutical chemistry Medical genetics Medicinal Chemistry Pharmaceutics Clinical Genetics |
ISBN | 3-030-56619-6 |
Formato | Materiale a stampa ![]() |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto | An Overview of Retinal Diseases and Current Ocular Drug Discovery -- Ocular Pharmacokinetics and Drug Delivery Challenges -- Models of Pathologies Associated with Age-related Macular Degeneration and Their Utilities in Drug Discovery -- Recent Developments in Agents for the Treatment of Age-Related Macular Degeneration and Stargardt Disease -- Targets and Strategies toward the Development of Therapeutics for Diabetic Retinopathy and Diabetic Macular Edema -- Recent Developments for the Treatment of Glaucoma -- Emerging Gene Therapy Treatments for Retinal Degenerative Diseases. . |
Record Nr. | UNINA-9910863166203321 |
Springer International Publishing, 2020 | ||
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Lo trovi qui: Univ. Federico II | ||
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Drug Delivery Systems: Advanced Technologies Potentially Applicable in Personalised Treatment [[electronic resource] /] / edited by Jorge Coelho |
Edizione | [1st ed. 2013.] |
Pubbl/distr/stampa | Dordrecht : , : Springer Netherlands : , : Imprint : Springer, , 2013 |
Descrizione fisica | 1 online resource (432 p.) |
Disciplina | 615.19 |
Collana | Advances in Predictive, Preventive and Personalised Medicine |
Soggetto topico |
Medicine
Diabetes Medicinal chemistry Polymers Biomedicine, general Medicinal Chemistry Polymer Sciences |
ISBN |
1-299-40828-1
94-007-6010-8 |
Formato | Materiale a stampa ![]() |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto | Polymers in Drug Delivery: Concepts, Developments and Potential.- Amphiphilic Molecules in Drug Delivery Systems -- Sizing nanoparticles in liquids: an overview of methods -- Nanoparticles for oral delivery of insulin -- Bioartificial pancreas: in the road to clinical application -- Cationic liposome-based systems for nucleic acid delivery: from the formulation development to therapeutic applications -- Biomaterial-based vectors for targeted delivery of nucleic acids to the nervous system -- Three-dimensional (3D) scaffolds as drug delivery devices for Tissue engineering applications -- The Warburg Effect is a Guide to Multipurpose Cancer Therapy Including Trace Element Delivery -- In silico research in drug delivery systems -- The Importance of Controlled/Living Radical Polymerization Techniques in the Design of Tailor Made Nanoparticles for DSS. |
Record Nr. | UNINA-9910438126103321 |
Dordrecht : , : Springer Netherlands : , : Imprint : Springer, , 2013 | ||
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Lo trovi qui: Univ. Federico II | ||
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Drug Design [[electronic resource] ] : Methodology, Concepts, and Mode-of-Action / / by Gerhard Klebe |
Autore | Klebe Gerhard |
Edizione | [1st ed. 2013.] |
Pubbl/distr/stampa | Berlin, Heidelberg : , : Springer Berlin Heidelberg : , : Imprint : Springer, , 2013 |
Descrizione fisica | 1 online resource (496 illus., 333 illus. in color. eReference.) |
Disciplina | 610 |
Soggetto topico |
Medicine
Pharmacology Pharmaceutical technology Medicinal chemistry Pharmacy Biomedicine, general Pharmacology/Toxicology Pharmaceutical Sciences/Technology Medicinal Chemistry Medicine/Public Health, general |
ISBN | 3-642-17907-X |
Formato | Materiale a stampa ![]() |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto | Part I Fundamentals in Drug Research -- 1. Drug Research Yesterday, Today and Tomorrow -- 2. The Role of Serendipity in Drug Research -- 3. Classical Drug Research -- 4. Protein–Ligand Interactions as the Basis for Drug Action -- 5. Optical Activity and Biological Effects -- Part II Discovery and Optimization of Lead Compounds -- 6. Screening for Lead Structures -- 7. Screening Technologies for Lead Discovery -- 8. Optimization of Lead Structures -- 9. Designing prodrugs -- 10. Peptidomimetics -- Part III Experimental and Theoretical Methods -- 11. Combinatorics: Chemistry With Big Numbers -- 12. Gene Technology in drug research -- 13. Experimental Methods of Structure Determination -- 14. The Spatial Structure of Biomolecules -- 15. Molecular Modelling -- 16. Conformational Analysis -- Part IV Structure–Activity Relationships and Design Approaches -- 17.Pharmacophore Hypothesis and Molecular Comparisons -- 18. Quantitative Structure–Activity Relationships -- 19. From in vitro to in vivo: Optimization of ADME-Tox Properties -- 20. Protein Modeling and Structure-Based Drug Design -- 21. A Case Study: Structure-Based Inhibtor Design for tRNA-Guanine Transglycosylase -- Part V. Drugs and drug action: Successes of structure-based design -- 22. How drugs act: Concepts for therapy -- 23. Inhibitors of hydrolases With an acyl-enzyme intermediate -- 24. Asparticprotease inhibitors -- 25. Inhibitors of hydrolysing metalloenzymes -- 26. Inhibitors of transferases -- 27. Inhibitors of oxidoreductases -- 28. Agonists and antagonists of nuclear receptors -- 29. Agonists and antagonists of membrane-bound -- 30. Ligands for channels, pores and transporters -- 31. Ligands for surface receptors -- 32. Biologicals: Peptides, proteins, nucleotides and macrolides as drugs. |
Record Nr. | UNINA-9910437839503321 |
Klebe Gerhard
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Berlin, Heidelberg : , : Springer Berlin Heidelberg : , : Imprint : Springer, , 2013 | ||
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Lo trovi qui: Univ. Federico II | ||
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