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Cycloadditions in Bioorthogonal Chemistry [[electronic resource] /] / edited by Milan Vrabel, Thomas Carell
Cycloadditions in Bioorthogonal Chemistry [[electronic resource] /] / edited by Milan Vrabel, Thomas Carell
Edizione [1st ed. 2016.]
Pubbl/distr/stampa Cham : , : Springer International Publishing : , : Imprint : Springer, , 2016
Descrizione fisica 1 online resource (V, 157 p. 88 illus., 42 illus. in color.)
Disciplina 547
Collana Topics in Current Chemistry Collections
Soggetto topico Bioorganic chemistry
Medicinal chemistry
Genetic engineering
Bioorganic Chemistry
Medicinal Chemistry
Genetic Engineering
ISBN 3-319-29686-8
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Bioorthogonal Chemistry: Introduction and Overview -- Transition Metal Catalyzed Bioorthogonal Cycloaddition Reactions -- Strain-Promoted 1,3-Dipolar Cycloaddition of Cycloalkynes and Organic Azides -- Photo-triggered Click Chemistry for Biological Applications -- Inverse Electron-Demand Diels-Alder Bioorthogonal Reactions -- Cycloadditions for Studying Nucleic Acids.
Record Nr. UNINA-9910254026303321
Cham : , : Springer International Publishing : , : Imprint : Springer, , 2016
Materiale a stampa
Lo trovi qui: Univ. Federico II
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Designing Receptors for the Next Generation of Biosensors [[electronic resource] /] / edited by Sergey A. Piletsky, Michael J. Whitcombe
Designing Receptors for the Next Generation of Biosensors [[electronic resource] /] / edited by Sergey A. Piletsky, Michael J. Whitcombe
Edizione [1st ed. 2013.]
Pubbl/distr/stampa Berlin, Heidelberg : , : Springer Berlin Heidelberg : , : Imprint : Springer, , 2013
Descrizione fisica 1 online resource (270 p.)
Disciplina 610/.28
Collana Springer Series on Chemical Sensors and Biosensors, Methods and Applications
Soggetto topico Chemical engineering
Analytical chemistry
Medicinal chemistry
Bioorganic chemistry
Biomedical engineering
Biomaterials
Industrial Chemistry/Chemical Engineering
Analytical Chemistry
Medicinal Chemistry
Bioorganic Chemistry
Biomedical Engineering and Bioengineering
ISBN 1-283-64063-5
3-642-32329-4
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Multichannel Sensors Based on Biphenyl and Cyclohexane Conformational Changes -- Learning from Proteins and Drugs: Receptors that Mimic Biomedically Important Binding Motifs -- Molecular Recognition of Nucleotides -- Molecular Recognition of Oligopeptides and Protein Surfaces -- Antimicrobial Peptides for Detection and Diagnostic Assays -- Plastic Antibodies -- Computational Approaches in the Design of Synthetic Receptors -- MIP Sensors on the Way to Real-World Applications -- Molecularly Imprinted Au Nanoparticle Composites for Selective Sensing Applications -- Design and Development of in vivo Sensor Systems: The Long and Tortured Road to a Self-Contained, Implantable Glucose Sensor for Diabetes Management -- Evolving Trends in Transition Metal-Modified Receptor Design and Function.
Record Nr. UNINA-9910437799503321
Berlin, Heidelberg : , : Springer Berlin Heidelberg : , : Imprint : Springer, , 2013
Materiale a stampa
Lo trovi qui: Univ. Federico II
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Development of Chemistry-Based Screening Platform for Access to Mirror-Image Library of Natural Products [[electronic resource] /] / by Taro Noguchi
Development of Chemistry-Based Screening Platform for Access to Mirror-Image Library of Natural Products [[electronic resource] /] / by Taro Noguchi
Autore Noguchi Taro
Edizione [1st ed. 2018.]
Pubbl/distr/stampa Singapore : , : Springer Singapore : , : Imprint : Springer, , 2018
Descrizione fisica 1 online resource (XIV, 80 p. 46 illus., 18 illus. in color.)
Disciplina 572.36
Collana Springer Theses, Recognizing Outstanding Ph.D. Research
Soggetto topico Medicinal chemistry
Organic chemistry
Pharmaceutical technology
Medicinal Chemistry
Organic Chemistry
Pharmaceutical Sciences/Technology
ISBN 981-10-6623-X
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Introduction -- Development of a Mirror-image Screening Process by Using Synthetic Proteins -- Synthesis of Grb2 SH2 Domain Proteins for Mirror-image Screening Systems -- Conclusions.
Record Nr. UNINA-9910298588103321
Noguchi Taro  
Singapore : , : Springer Singapore : , : Imprint : Springer, , 2018
Materiale a stampa
Lo trovi qui: Univ. Federico II
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Development of Novel Anti-HIV Pyrimidobenzothiazine Derivatives [[electronic resource] /] / by Tsukasa Mizuhara
Development of Novel Anti-HIV Pyrimidobenzothiazine Derivatives [[electronic resource] /] / by Tsukasa Mizuhara
Autore Mizuhara Tsukasa
Edizione [1st ed. 2013.]
Pubbl/distr/stampa Tokyo : , : Springer Japan : , : Imprint : Springer, , 2013
Descrizione fisica 1 online resource (157 p.)
Disciplina 616.9792
Collana Springer Theses, Recognizing Outstanding Ph.D. Research
Soggetto topico Organic chemistry
Pharmaceutical technology
Medicinal chemistry
Virology
Organic Chemistry
Pharmaceutical Sciences/Technology
Medicinal Chemistry
ISBN 4-431-54445-3
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Introduction -- Development of Divergent Synthetic Methods of Pyrimidobenzothiazine and Related Tricyclic Heterocycles -- Structure–Activity Relationship Study of PD 404182 Derivatives for the Highly Potent Anti-HIV Agents.- Design and Synthesis of Photoaffinity Probes and Their Application to Target Identification Study of PD 404182 -- Conclusion.
Record Nr. UNINA-9910437811403321
Mizuhara Tsukasa  
Tokyo : , : Springer Japan : , : Imprint : Springer, , 2013
Materiale a stampa
Lo trovi qui: Univ. Federico II
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Development of Novel Hydrogen-Bond Donor Catalysts [[electronic resource] /] / by Tsubasa Inokuma
Development of Novel Hydrogen-Bond Donor Catalysts [[electronic resource] /] / by Tsubasa Inokuma
Autore Inokuma Tsubasa
Edizione [1st ed. 2013.]
Pubbl/distr/stampa Tokyo : , : Springer Japan : , : Imprint : Springer, , 2013
Descrizione fisica 1 online resource (118 p.)
Disciplina 547.215
Collana Springer Theses, Recognizing Outstanding Ph.D. Research
Soggetto topico Organic chemistry
Medicinal chemistry
Catalysis
Organic Chemistry
Medicinal Chemistry
ISBN 1-299-19802-3
4-431-54231-0
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Introduction -- Development of HB donor catalysts -- Development and properties of novel HB donor catalysts -- Asymmetric Michael addition to alpha,beta-unsaturated imides catalyzed by HB donors -- Asymmetric Hydrazination of activated methylene compounds catalyzed by HB donors -- Development of hydroxy thiourea catalysts -- Asymmetric Michael addition of gamma-hydroxyenones and alkenylboronic acids -- Asymmetric Petasis Reaction of N-aryl-alpha-iminoamides and Alkenylboronates -- Conclusion.
Record Nr. UNINA-9910437807603321
Inokuma Tsubasa  
Tokyo : , : Springer Japan : , : Imprint : Springer, , 2013
Materiale a stampa
Lo trovi qui: Univ. Federico II
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Dietary Chinese Herbs [[electronic resource] ] : Chemistry, Pharmacology and Clinical Evidence / / edited by Yanze Liu, Zhimin Wang, Junzeng Zhang
Dietary Chinese Herbs [[electronic resource] ] : Chemistry, Pharmacology and Clinical Evidence / / edited by Yanze Liu, Zhimin Wang, Junzeng Zhang
Edizione [1st ed. 2015.]
Pubbl/distr/stampa Vienna : , : Springer Vienna : , : Imprint : Springer, , 2015
Descrizione fisica 1 online resource (776 p.)
Disciplina 615.3210951
Soggetto topico Food—Biotechnology
Clinical nutrition
Plant systematics
Plant taxonomy
Medicinal chemistry
Food Science
Clinical Nutrition
Plant Systematics/Taxonomy/Biogeography
Medicinal Chemistry
ISBN 3-211-99448-3
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Introduction -- Root, rhizome, tuber, and bulb materials -- Fruit or seed materials -- Aerial part, stem, stem bark, or leaf materials -- Flower or flower bud materials -- Multiple-part materials -- Fungi, marine algae, and other materials.
Record Nr. UNINA-9910298614603321
Vienna : , : Springer Vienna : , : Imprint : Springer, , 2015
Materiale a stampa
Lo trovi qui: Univ. Federico II
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Drug Delivery Challenges and Novel Therapeutic Approaches for Retinal Diseases [[electronic resource] /] / edited by Christopher L. Cioffi
Drug Delivery Challenges and Novel Therapeutic Approaches for Retinal Diseases [[electronic resource] /] / edited by Christopher L. Cioffi
Edizione [1st ed. 2020.]
Pubbl/distr/stampa Cham : , : Springer International Publishing : , : Imprint : Springer, , 2020
Descrizione fisica 1 online resource (IX, 272 p. 1 illus.)
Disciplina 615.19
Collana Topics in Medicinal Chemistry
Soggetto topico Medicinal chemistry
Ophthalmology
Pharmaceutical chemistry
Medical genetics
Medicinal Chemistry
Pharmaceutics
Clinical Genetics
ISBN 3-030-56619-6
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto An Overview of Retinal Diseases and Current Ocular Drug Discovery -- Ocular Pharmacokinetics and Drug Delivery Challenges -- Models of Pathologies Associated with Age-related Macular Degeneration and Their Utilities in Drug Discovery -- Recent Developments in Agents for the Treatment of Age-Related Macular Degeneration and Stargardt Disease -- Targets and Strategies toward the Development of Therapeutics for Diabetic Retinopathy and Diabetic Macular Edema -- Recent Developments for the Treatment of Glaucoma -- Emerging Gene Therapy Treatments for Retinal Degenerative Diseases. .
Record Nr. UNINA-9910420948603321
Cham : , : Springer International Publishing : , : Imprint : Springer, , 2020
Materiale a stampa
Lo trovi qui: Univ. Federico II
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Drug Delivery Challenges and Novel Therapeutic Approaches for Retinal Diseases / / edited by Christopher L. Cioffi
Drug Delivery Challenges and Novel Therapeutic Approaches for Retinal Diseases / / edited by Christopher L. Cioffi
Edizione [1st ed. 2020.]
Pubbl/distr/stampa Springer International Publishing, 2020
Descrizione fisica 1 online resource (IX, 272 p. 1 illus.)
Disciplina 615.19
Collana Topics in Medicinal Chemistry
Soggetto topico Medicinal chemistry
Ophthalmology
Pharmaceutical chemistry
Medical genetics
Medicinal Chemistry
Pharmaceutics
Clinical Genetics
ISBN 3-030-56619-6
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto An Overview of Retinal Diseases and Current Ocular Drug Discovery -- Ocular Pharmacokinetics and Drug Delivery Challenges -- Models of Pathologies Associated with Age-related Macular Degeneration and Their Utilities in Drug Discovery -- Recent Developments in Agents for the Treatment of Age-Related Macular Degeneration and Stargardt Disease -- Targets and Strategies toward the Development of Therapeutics for Diabetic Retinopathy and Diabetic Macular Edema -- Recent Developments for the Treatment of Glaucoma -- Emerging Gene Therapy Treatments for Retinal Degenerative Diseases. .
Record Nr. UNINA-9910863166203321
Springer International Publishing, 2020
Materiale a stampa
Lo trovi qui: Univ. Federico II
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Drug Delivery Systems: Advanced Technologies Potentially Applicable in Personalised Treatment [[electronic resource] /] / edited by Jorge Coelho
Drug Delivery Systems: Advanced Technologies Potentially Applicable in Personalised Treatment [[electronic resource] /] / edited by Jorge Coelho
Edizione [1st ed. 2013.]
Pubbl/distr/stampa Dordrecht : , : Springer Netherlands : , : Imprint : Springer, , 2013
Descrizione fisica 1 online resource (432 p.)
Disciplina 615.19
Collana Advances in Predictive, Preventive and Personalised Medicine
Soggetto topico Medicine
Diabetes
Medicinal chemistry
Polymers  
Biomedicine, general
Medicinal Chemistry
Polymer Sciences
ISBN 1-299-40828-1
94-007-6010-8
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Polymers in Drug Delivery: Concepts, Developments and Potential.- Amphiphilic Molecules in Drug Delivery Systems -- Sizing nanoparticles in liquids: an overview of methods -- Nanoparticles for oral delivery of insulin -- Bioartificial pancreas: in the road to clinical application -- Cationic liposome-based systems for nucleic acid delivery: from the formulation development to therapeutic applications -- Biomaterial-based vectors for targeted delivery of nucleic acids to the nervous system -- Three-dimensional (3D) scaffolds as drug delivery devices for Tissue engineering applications -- The Warburg Effect is a Guide to Multipurpose Cancer Therapy Including Trace Element Delivery -- In silico research in drug delivery systems -- The Importance of Controlled/Living Radical Polymerization Techniques in the Design of Tailor Made Nanoparticles for DSS.
Record Nr. UNINA-9910438126103321
Dordrecht : , : Springer Netherlands : , : Imprint : Springer, , 2013
Materiale a stampa
Lo trovi qui: Univ. Federico II
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Drug Design [[electronic resource] ] : Methodology, Concepts, and Mode-of-Action / / by Gerhard Klebe
Drug Design [[electronic resource] ] : Methodology, Concepts, and Mode-of-Action / / by Gerhard Klebe
Autore Klebe Gerhard
Edizione [1st ed. 2013.]
Pubbl/distr/stampa Berlin, Heidelberg : , : Springer Berlin Heidelberg : , : Imprint : Springer, , 2013
Descrizione fisica 1 online resource (496 illus., 333 illus. in color. eReference.)
Disciplina 610
Soggetto topico Medicine
Pharmacology
Pharmaceutical technology
Medicinal chemistry
Pharmacy
Biomedicine, general
Pharmacology/Toxicology
Pharmaceutical Sciences/Technology
Medicinal Chemistry
Medicine/Public Health, general
ISBN 3-642-17907-X
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Part I  Fundamentals in Drug Research -- 1. Drug Research Yesterday, Today and Tomorrow -- 2. The Role of Serendipity in Drug Research -- 3. Classical Drug Research -- 4. Protein–Ligand Interactions as the Basis for Drug Action -- 5. Optical Activity and Biological Effects -- Part II Discovery and Optimization of Lead Compounds --  6. Screening for Lead Structures -- 7.  Screening Technologies for Lead Discovery -- 8. Optimization of Lead Structures -- 9. Designing prodrugs -- 10. Peptidomimetics -- Part III  Experimental and Theoretical Methods -- 11. Combinatorics: Chemistry With Big Numbers -- 12. Gene Technology in drug research --  13. Experimental Methods of Structure Determination -- 14. The Spatial Structure of Biomolecules -- 15. Molecular Modelling -- 16. Conformational Analysis -- Part IV Structure–Activity Relationships and Design Approaches -- 17.Pharmacophore Hypothesis and Molecular Comparisons -- 18. Quantitative Structure–Activity Relationships -- 19.  From in vitro to in vivo: Optimization of ADME-Tox Properties -- 20. Protein Modeling and Structure-Based Drug Design -- 21.  A Case Study: Structure-Based Inhibtor Design for tRNA-Guanine Transglycosylase -- Part V. Drugs and drug action: Successes of structure-based design -- 22. How drugs act: Concepts for therapy -- 23. Inhibitors of hydrolases With an acyl-enzyme intermediate -- 24. Asparticprotease inhibitors -- 25. Inhibitors of hydrolysing metalloenzymes -- 26. Inhibitors of transferases -- 27. Inhibitors of oxidoreductases -- 28.  Agonists and antagonists of nuclear receptors -- 29. Agonists and antagonists of membrane-bound -- 30. Ligands for channels, pores and transporters -- 31. Ligands for surface receptors -- 32. Biologicals: Peptides, proteins, nucleotides and macrolides as drugs.
Record Nr. UNINA-9910437839503321
Klebe Gerhard  
Berlin, Heidelberg : , : Springer Berlin Heidelberg : , : Imprint : Springer, , 2013
Materiale a stampa
Lo trovi qui: Univ. Federico II
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