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Chemical Epigenetics [[electronic resource] /] / edited by Antonello Mai
| Chemical Epigenetics [[electronic resource] /] / edited by Antonello Mai |
| Edizione | [1st ed. 2020.] |
| Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2020 |
| Descrizione fisica | 1 online resource (IX, 567 p. 80 illus., 50 illus. in color.) |
| Disciplina | 572.86 |
| Collana | Topics in Medicinal Chemistry |
| Soggetto topico |
Medicinal chemistry
Genetics Enzymology Chemical engineering Medicinal Chemistry Genetics and Genomics Industrial Chemistry/Chemical Engineering |
| ISBN | 3-030-42982-2 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Targeting the Zinc-Dependent Histone Deacetylases (HDACs) for Drug Discovery -- Hydroxamic Acid-Containing Peptides in the Study of Histone Deacetylases -- Sirtuin Inhibitors and Activators -- Histone Acetyltransferase Enzymes: From Biological Implications to Most Relevant Inhibitors -- Lysine Methyltransferases and Their Inhibitors -- PRMT Inhibitors -- Lysine-Specific Histone Demethylases 1/2 (LSD1/2) and Their Inhibitors -- Inhibitors of JmjC-Containing Histone Demethylases -- Chemical Compounds Targeting DNA Methylation and Hydroxymethylation -- Applied Biophysics for Bromodomain Drug Discovery -- Methyl-Readers and Inhibitors -- Altered Long Non-coding RNA Expression in Cancer: Potential Biomarkers and Therapeutic Targets? - Acetylation and Methylation in Asthma, COPD, and Lung Cancer -- Structure-Based Design ofEpigenetic Inhibitors -- Experimental Methodologies for Detection and Mapping of Epigenetic DNA Marks -- Advanced Assays in Epigenetics. |
| Record Nr. | UNINA-9910410051303321 |
| Cham : , : Springer International Publishing : , : Imprint : Springer, , 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Chemistry in 17th-Century New England [[electronic resource] /] / by Gary Patterson
| Chemistry in 17th-Century New England [[electronic resource] /] / by Gary Patterson |
| Autore | Patterson Gary |
| Edizione | [1st ed. 2020.] |
| Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2020 |
| Descrizione fisica | 1 online resource (VIII, 94 p. 41 illus., 17 illus. in color.) |
| Disciplina | 540.974 |
| Collana | History of Chemistry |
| Soggetto topico |
Chemistry - History
Medicinal chemistry Pharmacology History of Chemistry History of the Americas Medicinal Chemistry Pharmacology/Toxicology |
| ISBN | 3-030-43261-0 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Introduction -- The Puritan Mind in the 17th Century -- The Errand into the Wilderness -- John Winthrop, Jr.: The Making of an Adept -- Ipswich: Founding a Town in New England -- Return to England (1641) and the New England Ironworks -- New London and the Alchemical Plantation -- Obtaining the Charter for Connecticut and Election to the Royal Society of London -- The Winthrop Circle in New England -- Harvard College and 17th Century Chemistry -- Conclusions and Reflections. |
| Record Nr. | UNINA-9910410043503321 |
Patterson Gary
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| Cham : , : Springer International Publishing : , : Imprint : Springer, , 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Chemistry of Antibiotics and Related Drugs [[electronic resource] /] / by Mrinal K. Bhattacharjee
| Chemistry of Antibiotics and Related Drugs [[electronic resource] /] / by Mrinal K. Bhattacharjee |
| Autore | Bhattacharjee Mrinal K |
| Edizione | [1st ed. 2016.] |
| Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2016 |
| Descrizione fisica | 1 online resource (XII, 219 p. 98 illus., 32 illus. in color.) |
| Disciplina | 615.7922 |
| Soggetto topico |
Medicinal chemistry
Medical biochemistry Microbiology Pharmacy Pharmacology Medicinal Chemistry Medical Biochemistry Pharmacology/Toxicology |
| ISBN | 3-319-40746-5 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Introduction -- Antibiotic resistance development -- Major classes of antibiotics -- Relevant concepts in Biochemistry -- The cell wall as a target -- Mechanism of resistance to B-lactams -- Antibiotic Vancomycin -- Antibiotics that inhibit nucleotide synthesis -- Antibiotics that inhibit DNA synthesis -- Drugs that cause DNA cleavage -- Antibiotics that inhibit RNA synthesis -- Antibiotics that inhibit RNA synthesis -- Antibiotics that disrupt membrane structure. |
| Record Nr. | UNINA-9910254059403321 |
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Bhattacharjee Mrinal K
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| Cham : , : Springer International Publishing : , : Imprint : Springer, , 2016 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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The Chemistry of Benzotriazole Derivatives [[electronic resource] ] : A Tribute to Alan Roy Katritzky / / edited by Jean-Christophe M. Monbaliu
| The Chemistry of Benzotriazole Derivatives [[electronic resource] ] : A Tribute to Alan Roy Katritzky / / edited by Jean-Christophe M. Monbaliu |
| Edizione | [1st ed. 2016.] |
| Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2016 |
| Descrizione fisica | 1 online resource (XI, 289 p. 431 illus., 19 illus. in color.) |
| Disciplina | 572 |
| Collana | Topics in Heterocyclic Chemistry |
| Soggetto topico |
Bioorganic chemistry
Carbohydrates Medicinal chemistry Bioorganic Chemistry Carbohydrate Chemistry Medicinal Chemistry |
| ISBN | 3-319-31554-4 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Preparation, properties and utility of simple benzotriazole derivatives -- Acylbenzotriazoles: new allies for short linear and cyclic peptide constructs -- Benzotriazole-based strategies towards peptidomimetics, conjugates and other peptide derivatives -- Benzotriazole-mediated synthesis of oxygen containing heterocycles -- Benzotriazole-mediated synthesis of nitrogen containing heterocycles -- Benzotriazole: much more than just synthetic heterocyclic chemistry. |
| Record Nr. | UNINA-9910768162203321 |
| Cham : , : Springer International Publishing : , : Imprint : Springer, , 2016 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Chemistry of Plant Natural Products [[electronic resource] ] : Stereochemistry, Conformation, Synthesis, Biology, and Medicine / / by Sunil Kumar Talapatra, Bani Talapatra
| Chemistry of Plant Natural Products [[electronic resource] ] : Stereochemistry, Conformation, Synthesis, Biology, and Medicine / / by Sunil Kumar Talapatra, Bani Talapatra |
| Autore | Talapatra Sunil Kumar |
| Edizione | [1st ed. 2015.] |
| Pubbl/distr/stampa | Berlin, Heidelberg : , : Springer Berlin Heidelberg : , : Imprint : Springer, , 2015 |
| Descrizione fisica | 1 online resource (1196 p.) |
| Disciplina | 547.7 |
| Soggetto topico |
Organic chemistry
Medicinal chemistry Pharmacology Biochemistry Pharmacy Organic Chemistry Medicinal Chemistry Pharmacology/Toxicology Biochemistry, general |
| ISBN | 3-642-45410-0 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Introduction: enzymes, cofactors/coenzymes, primary and secondary metabolites, natural products and their functions, plant chemical ecology, biosynthesis, metabolic pathways -- Fundamental Stereochemical Concepts and Nomenclatures -- Important Biological Events Occurring in Plants -- Natural Products Chemistry -- Biosynthesis of Terpenoids, The Oldest Natural Products -- Monoterpenoids (C10) -- Sesquiterpenoids (C15) -- Diterpenoids (C20) -- Sesterpenoids (C25) -- Triterpenes -- Steroids: Cholesterol and Other Phytosterols -- Carotenoids-GGPP Derived Polyisoprenoid (C40) Coloring Pigments -- Shikimic Acid Pathway -- Polyketide Pathway, Biosynthesis of Diverse Clases of Aromatic Compounds -- Alkaloids: General Introduction -- Hygrine, Hygroline and Cuscohygrine (Ornithine-Derived Alkaloids) -- Coniine, Conhydrine and Pseudoconhydrine -- Nicotine -- Atropine [(±)-Hyoscyamine] and Cocaine -- Ephedrine and Pseudoephedrine -- Pilocarpine and Isopilocarpine -- Papaverine -- Morphine, Codeine, Thebaine -- Colchicine -- Quinine: Cinchona Alkalods -- Reserpine -- Strychnine, an Alkaloid with Heptacyclic Dense Molecular Scaffold -- Dimeric Indole Alkaloids:Vinblastine (Vincaleukoblastine), Vineristine (Leurocristine) and Their Derivatives -- Some More Alkaloids Having Diverse Skeletal Patterns -- Important Outcomes of Chemical Studies on Natural Products -- Chiral Recognition in Biological Systems and Natural Chiral Auxiliaries -- Natural Products in the Parlor of Pharmaceuticals -- Organic Phytonutrients and Their Functions -- Appendices. . |
| Record Nr. | UNINA-9910298628003321 |
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Talapatra Sunil Kumar
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| Berlin, Heidelberg : , : Springer Berlin Heidelberg : , : Imprint : Springer, , 2015 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Chemistry, Biochemistry and Pharmacology of Hydrogen Sulfide [[electronic resource] /] / edited by Philip K. Moore, Matt Whiteman
| Chemistry, Biochemistry and Pharmacology of Hydrogen Sulfide [[electronic resource] /] / edited by Philip K. Moore, Matt Whiteman |
| Edizione | [1st ed. 2015.] |
| Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2015 |
| Descrizione fisica | 1 online resource (384 p.) |
| Disciplina | 546.723 |
| Collana | Handbook of Experimental Pharmacology |
| Soggetto topico |
Pharmacology
Human physiology Neurosciences Medical biochemistry Medicinal chemistry Pharmacology/Toxicology Human Physiology Medical Biochemistry Medicinal Chemistry |
| ISBN | 3-319-18144-0 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Part I Biochemistry, molecular biology and chemistry -- 1 H2Ssynthesizing enzymes: biochemistry and molecular aspects -- Part II Molecular mechanisms of action -- 2 Sulfhydration and H2S -- 3 Persulfide formation and H2S -- Part III Cardiovascular system -- 4 H2S and blood vessels - an overview -- 5 Hydrogen sulfide and urogenital tract -- 6 H2S - cardiac function and cardiac disease -- 7 H2S and platelets – a possible role in thrombosis? -- Part IV Inflammation and inflammatory disease -- 8 H2S and inflammation - an overview -- 9 H2S and neuroinflammation -- Part V H2S and the nervous system -- 10 Brain, learning and memory: role in neurodegenerative diseases -- 11 H2S and pain – inflammatory and neuropathic -- Part VI H2S, angiogenesis and cancer -- 12 H2S and colon cancer -- 13 The role of H2S in cancer and tumor development -- Part VII H2S and ageing -- 14 H2S – a new approach to lifespan enhancement and healthy aging? -- Part VIII H2S, measurement and possible therapeutics? -- 15 Measurement of H2S – probes comes of age? -- 16 S-propargylcysteine – a novel H2S donor with therapeutic potential -- 17 Mitochondria-targetted sulfide donors -- 18 Medicinal chemistry - insights into the development of novel H2S donors. |
| Record Nr. | UNINA-9910298444303321 |
| Cham : , : Springer International Publishing : , : Imprint : Springer, , 2015 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Chemokines [[electronic resource] ] : Chemokines and Their Receptors in Drug Discovery / / edited by Nuska Tschammer
| Chemokines [[electronic resource] ] : Chemokines and Their Receptors in Drug Discovery / / edited by Nuska Tschammer |
| Edizione | [1st ed. 2015.] |
| Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2015 |
| Descrizione fisica | 1 online resource (248 p.) |
| Disciplina | 616.079 |
| Collana | Topics in Medicinal Chemistry |
| Soggetto topico |
Medicinal chemistry
Proteins Pharmaceutical technology Medicinal Chemistry Receptors Pharmaceutical Sciences/Technology |
| ISBN | 3-319-14060-4 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Introduction -- Insights in the chemokine receptor structures and drug design approaches in chemokine receptors -- Therapeutic targeting of CXCR3 chemokine receptor by small molecules -- Allosteric modulation of chemokine receptors -- Chemokines and their receptors in CNS -- Chemokine receptors in allergy and inflammation. |
| Record Nr. | UNINA-9910298621503321 |
| Cham : , : Springer International Publishing : , : Imprint : Springer, , 2015 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Chitin and Chitosan for Regenerative Medicine [[electronic resource] /] / edited by Pradip Kumar Dutta
| Chitin and Chitosan for Regenerative Medicine [[electronic resource] /] / edited by Pradip Kumar Dutta |
| Edizione | [1st ed. 2016.] |
| Pubbl/distr/stampa | New Delhi : , : Springer India : , : Imprint : Springer, , 2016 |
| Descrizione fisica | 1 online resource (387 p.) |
| Disciplina | 571.889 |
| Collana | Springer Series on Polymer and Composite Materials |
| Soggetto topico |
Polymers
Biomaterials Biochemical engineering Medicinal chemistry Polymer Sciences Biochemical Engineering Medicinal Chemistry |
| ISBN | 81-322-2511-2 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Preface; Contents; About the Editor; Part I Focus on Tissue Engineering; Chitosan Hydrogels for Regenerative Engineering ; Abstract ; 1 Introduction; 1.1 Chitosan; 1.2 Hydrogels; 2 Chitosan Hydrogels; 2.1 Physically Crosslinked Chitosan Hydrogels; 2.1.1 Thermogelling Hydrogels; 2.1.2 pH-Mediated Gelation; 2.1.3 Polyelectrolyte Complexes (PECs); 2.2 Chemically Crosslinked Hydrogels; 2.2.1 Chemically Crosslinked Hydrogels Using Exogenous Crosslinkers; 2.2.2 Photocrosslinked Hydrogels; 2.2.3 Enzymatically Crosslinked Hydrogels; 3 Chitosan Hydrogel for Regenerative Engineering Applications
3.1 Orthopedic Regenerative Engineering3.2 Cartilage Regenerative Engineering; 3.3 Neural Regenerative Engineering; 3.4 Corneal Regenerative Engineering; 3.5 Intestinal Regenerative Engineering; 3.6 Adipose Regenerative Engineering; 3.7 Liver Regenerative Engineering; 3.8 Intervertebral Disk Regenerative Engineering; 3.9 Cardiac Regenerative Engineering; 3.10 Skin Regenerative Engineering; 3.11 Ligament Regenerative Engineering; 4 Conclusions; References; Prospects of Bioactive Chitosan-Based Scaffolds in Tissue Engineering and Regenerative Medicine ; Abstract ; 1 Introduction 2 In Bone Tissue Engineering2.1 Chitosan-Synthetic Polymer Hybrid Scaffolds; 2.2 Chitosan-Calcium Phosphate Hybrid Scaffolds; 2.3 Chitosan-Bioactive Glass Hybrid Scaffolds; 2.4 Chitosan-Hydroxyapatite Hybrid Scaffolds; 3 In Cartilage Tissue Engineering; 3.1 Chitosan-Based Fibrous Scaffolds; 3.2 Chitosan-Based Scaffolds; 3.3 Chitosan-Based Composite Scaffolds; 4 In Liver Tissue Engineering; 4.1 Chitosan-Collagen Matrices; 4.2 Alginate-Chitosan Composite Matrices; 4.3 Chitosan-Based Microfibers; 5 In Nerve Tissue Engineering; 5.1 Chitosan-Based Membranes; 5.2 Chitosan-Based Hydrogels 6 In Musculoskeletal Tissue Engineering7 Concluding Remarks; References; Chitosan-Based Scaffolds for Cartilage Regeneration ; Abstract ; 1 Introduction; 2 Characteristics of Cartilage Damage and Reconstruction; 3 Superiorities of Chitosan-Based Scaffolds for Cartilage Regeneration; 4 Chitosan-Based Hydrogels for Cartilage Regeneration; 4.1 Physically Cross-Linked Hydrogels with Chitosan as Matrix; 4.2 Chitosan-Based Chemically Cross-Linked Hydrogels; 5 3D Porous Chitosan-Based Scaffolds; 5.1 Normal 3D Porous Chitosan-Based Scaffolds; 5.2 Fibrous Scaffolds with Chitosan as Matrix 5.3 Chitosan-Silk Scaffolds5.4 3D Printed Chitosan Scaffolds; 5.5 Dynamic Compression Chitosan Scaffolds; 5.6 Aggregated Chitosan-Particle Scaffolds; 6 Other Scaffolds with Chitosan as Matrix; 6.1 Blood Implant in Marrow Stimulation; 6.2 Chitosan-Based Cryogels; 6.3 Chitosan-Coated Scaffolds; 7 Summary and Future Directions; References; Composite Chitosan-Calcium Phosphate Scaffolds for Cartilage Tissue Engineering ; Abstract ; 1 Articular Cartilage; 2 Tissue Engineering; 3 Chitosan-Calcium Phosphate Scaffold; 4 Formation of Biphasic Constructs; 5 Collagen-Coated Scaffold Characteristics 6 Degradation |
| Record Nr. | UNINA-9910254045903321 |
| New Delhi : , : Springer India : , : Imprint : Springer, , 2016 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Circulating Nucleic Acids in Early Diagnosis, Prognosis and Treatment Monitoring [[electronic resource] ] : An Introduction / / edited by Peter B. Gahan
| Circulating Nucleic Acids in Early Diagnosis, Prognosis and Treatment Monitoring [[electronic resource] ] : An Introduction / / edited by Peter B. Gahan |
| Edizione | [1st ed. 2015.] |
| Pubbl/distr/stampa | Dordrecht : , : Springer Netherlands : , : Imprint : Springer, , 2015 |
| Descrizione fisica | 1 online resource (476 p.) |
| Disciplina | 612.0157 |
| Collana | Advances in Predictive, Preventive and Personalised Medicine |
| Soggetto topico |
Medicine
Health promotion Cancer research Nucleic acids Medicinal chemistry Biomedicine, general Health Promotion and Disease Prevention Cancer Research Nucleic Acid Chemistry Medicinal Chemistry |
| ISBN | 94-017-9168-6 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Part I. BACKGROUND -- CHAPTER 1 Introduction - Brief History and the present and future status of CNAPS -- CHAPTER 2 The biology of CNAPS -- Part II. METHODOLOGY -- CHAPTER 3 Pre-analytical requirements for analysing nucleic acids from blood -- CHAPTER 4. Circulating DNA and miRNA isolation -- CHAPTER 5 Detection of genetic alterations by nucleic acid analysis: use of pcr and mass spectroscopy-based methods -- CHAPTER 6 Genomic approaches to the analysis of cell free nucleic acids -- Part III APPLICATIONS -- CHAPTER 7 CNAPS and General Medicine -- CHAPTER 8 Fetal CNAPS – DNA/RNA -- CHAPTER 9 Circulating nucleic acids and Diabetes mellitus -- CHAPTER 10 Extracellular nucleic acids and cancer -- CHAPTER 11 Other bodily fluids as non-invasive sources of Cell-free DNA/RNA -- CHAPTER 12 CNAPS in therapy monitoring -- Part IV OTHER ASPECTCS -- CHAPTER 13 Quality Assurance -- CHAPTER 14 Societal Aspects: Ethics. |
| Record Nr. | UNINA-9910300235703321 |
| Dordrecht : , : Springer Netherlands : , : Imprint : Springer, , 2015 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Co-Evolution of Secondary Metabolites [[electronic resource] /] / edited by Jean-Michel Merillon, Kishan Gopal Ramawat
| Co-Evolution of Secondary Metabolites [[electronic resource] /] / edited by Jean-Michel Merillon, Kishan Gopal Ramawat |
| Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2020 |
| Disciplina | 660.6 |
| Collana | Reference Series in Phytochemistry |
| Soggetto topico |
Biotechnology
Plant biochemistry Bioorganic chemistry Plant pathology Plant ecology Medicinal chemistry Plant Biochemistry Bioorganic Chemistry Plant Pathology Plant Ecology Medicinal Chemistry |
| ISBN | 3-319-76887-5 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Intraspecific Diversity in Plant Secondary Metabolites -- Changes in Secondary Metabolites during adaptation of plants to life on land -- Secondary Metabolites in Pollination -- Allelochemicals -- Abiotic stress signals on secondary metabolites in plants -- Evolution of chemical ecology -- Co-evolution of host-parasite metabolites -- Vertebrates and sensory perception -- Genetics of secondary metabolites -- Secondary Metabolites in Host-parasite interaction -- Secondary metabolites in insect–plant interactions -- Bioactive molecules in plant defence. |
| Record Nr. | UNINA-9910416111803321 |
| Cham : , : Springer International Publishing : , : Imprint : Springer, , 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Soggetto topico
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Medicinal Chemistry
(209)
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- Organic Chemistry (62)
- Organic chemistry (57)
- Pharmaceutical Sciences/Technology (39)