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Skin Permeation and Disposition of Therapeutic and Cosmeceutical Compounds / / edited by Kenji Sugibayashi
| Skin Permeation and Disposition of Therapeutic and Cosmeceutical Compounds / / edited by Kenji Sugibayashi |
| Edizione | [1st ed. 2017.] |
| Pubbl/distr/stampa | Tokyo : , : Springer Japan : , : Imprint : Springer, , 2017 |
| Descrizione fisica | 1 online resource (X, 428 p. 153 illus., 78 illus. in color.) |
| Disciplina | 615.19 |
| Soggetto topico |
Pharmaceutical technology
Dermatology Medicinal chemistry Pharmaceutical Sciences/Technology Medicinal Chemistry |
| ISBN | 4-431-56526-4 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Part 1 GENERAL INTRODUCTION -- 1 Skin Morphology And Permeation Pathway Through Skin -- 2 Skin Permeation Of Chemicals -- 3 Skin Disposition Of Chemicals -- 4 Skin Metabolism Of Chemicals -- 5 Systematic Absorption Of Chemicals And Its Kinetics -- 6 Related Topic: Chemical Permeation Through Impaired Skin -- 7 Related Topic: Skin Permeation Of Topical Formulations -- 8 Related Topic: Halal Cosmetics -- Part 2 BASIC FORMULATIONS APPLIED TO SKIN -- 9 Liquid Formulations -- 10 Dermal Patches, Plasters And Cataplasms -- 11 Related Topic: Liposomes: Recent Advances & Future Perspective -- 12 Related Topic: Encapsulation Technologies: Polymeric Micelles In Dermal And Transdermal Delivery -- 13 Related Topic: Liquid Crystals In Dermal And Transdermal Delivery -- Part 3 SKIN PENETRATION ENHANCEMENT -- 14 Iontophoresis And Electroporation -- 15 Microneedle Array -- 16 Drug Delivery To Skin By Needle-Free Injector -- 17 Related Topic: Prodrug Approach -- 18 Related Topic: S/O Technique To Increase Skin Permeation -- 19 Related Topic: Cyclodextrin -- 20 Related Topic: Ion-Pair Strategy -- Part 4 SELECTION OF TOPICALLY APPLIED CHEMICAL CANDIDATES -- 21 Selection Of Topically Applied Chemical Candidates – TDDS -- 22 Drugs In Topical Formulations -- 23 Related Topic: Development Of Transdermal Drug Delivery System Using Self-Dissolving Microneedle Arrays Fabricated Using Hyaluronic Acid -- 24 Related Topic: Vaccines -- Part 5 SAFETY ASSESSMENT OF TOPICALLY APPLIED COMPOUNDS -- 25 Skin Damage Caused By Chemical Application -- 26 In Vitro Evaluation For Skin Toxicity -- 27 Related Topic: Safety Evaluation And Alternatives To Animal Testing -- 28 Related Topic: Safety Evaluation Of Nanomaterials -- Part 6．EXPERIMENTAL METHODS OF SKIN PERMEATION -- 29 In Vitro Methods -- 30 In Vivo Methods -- 31 Development Of Full-Thickness Human Skin Equivalents With Blood And Lymph-Like Capillary Networks By Cell Coating Technology -- 32 In Silico Approach -- 33 Related Topic: Measurement Of Diffusion Coefficient Of Chemicals -- 34 Related Topic: Determination Of Partition Coefficient From Vehicle To Skin -- 35 Related Topic: Use Of Pampa And Artificial Membranes -- 36 Related Topic: Drug Permeation Through Hair Follicle -- Part 7 COMMENTS FROM MEDICAL DOCTORS AND PHARMACISTS -- 37 Comments On The Topical Formulations From Medical Doctor -- 38 Comments On The Functional Cosmetics From Medical Doctor -- 39 Comments From Pharmacist -- 38 Comments On The Functional Cosmetics From Medical Doctor -- 39 Comments From Pharmacist. |
| Record Nr. | UNINA-9910253935403321 |
| Tokyo : , : Springer Japan : , : Imprint : Springer, , 2017 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Small Molecule Therapeutics for Schizophrenia / / edited by Sylvain Celanire, Sonia Poli
| Small Molecule Therapeutics for Schizophrenia / / edited by Sylvain Celanire, Sonia Poli |
| Edizione | [1st ed. 2015.] |
| Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2015 |
| Descrizione fisica | 1 online resource (327 p.) |
| Disciplina | 616.8982 |
| Collana | Topics in Medicinal Chemistry |
| Soggetto topico |
Medicinal chemistry
Psychopharmacology Neurosciences Medicinal Chemistry |
| ISBN | 3-319-11502-2 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Antipsychotics and the Dopamine–Serotonin Connection -- GLYT1 Inhibitors: From Hits to Clinical Candidates -- Metabotropic Glutamate Receptor 2 Activators -- Activation of the mGlu5 Receptor for the Treatment of Schizophrenia and Cognitive-Deficit-Associated Disorders -- Muscarinic Acetylcholine Receptor Activators -- Nicotinic Acetylcholine Receptor Modulators -- The Use of PDE10A and PDE9 Inhibitors for Treating Schizophrenia. |
| Record Nr. | UNINA-9910298626103321 |
| Cham : , : Springer International Publishing : , : Imprint : Springer, , 2015 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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The Smoothened Receptor in Cancer and Regenerative Medicine / / edited by Martial Ruat
| The Smoothened Receptor in Cancer and Regenerative Medicine / / edited by Martial Ruat |
| Edizione | [1st ed. 2015.] |
| Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2015 |
| Descrizione fisica | 1 online resource (213 p.) |
| Disciplina | 571.889 |
| Collana | Topics in Medicinal Chemistry |
| Soggetto topico |
Medicinal chemistry
Proteins Cancer research Medicinal Chemistry Receptors Cancer Research |
| ISBN | 3-319-19755-X |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Canonical and non canonical Hedgehog signaling pathways, coupling to G-proteins -- Pharmacochemistry of the Smoothened receptor: Agonists, antagonists, allosteric modulators -- Receptor modifications in Hedgehog regulation -- Smoothened, stem cell maintenance and brain diseases -- Medulloblastoma, pediatric brain tumors and Smoothened blockade -- Role of Smoothened and Hedgehog signaling in angiogenesis, neovascularization -- Implications in stem cell maintenance -- Comparison of the crystal structure of Smoothened to known GPCRs structure. |
| Record Nr. | UNINA-9910298609303321 |
| Cham : , : Springer International Publishing : , : Imprint : Springer, , 2015 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Solar Energy for Fuels / / edited by Harun Tüysüz, Candace K. Chan
| Solar Energy for Fuels / / edited by Harun Tüysüz, Candace K. Chan |
| Edizione | [1st ed. 2016.] |
| Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2016 |
| Descrizione fisica | 1 online resource (VII, 327 p. 165 illus., 126 illus. in color.) |
| Disciplina | 662.6 |
| Collana | Topics in Current Chemistry |
| Soggetto topico |
Catalysis
Ceramics Glass Composites (Materials) Composite materials Renewable energy resources Nanochemistry Medicinal chemistry Physical chemistry Ceramics, Glass, Composites, Natural Materials Renewable and Green Energy Medicinal Chemistry Physical Chemistry |
| ISBN | 3-319-23099-9 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910254052303321 |
| Cham : , : Springer International Publishing : , : Imprint : Springer, , 2016 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Solving a 3D Structural Puzzle / / by Casper Rønn Hoeck
| Solving a 3D Structural Puzzle / / by Casper Rønn Hoeck |
| Autore | Hoeck Casper Rønn |
| Edizione | [1st ed. 2018.] |
| Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2018 |
| Descrizione fisica | 1 online resource (xli, 238 pages) : illustrations |
| Disciplina | 543.0877 |
| Collana | Springer Theses, Recognizing Outstanding Ph.D. Research |
| Soggetto topico |
Spectroscopy
Microscopy Chemistry, Physical and theoretical Medicinal chemistry Spectroscopy/Spectrometry Spectroscopy and Microscopy Theoretical and Computational Chemistry Medicinal Chemistry |
| ISBN | 3-319-96172-1 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | NMR spectroscopy: Past to present -- Theory – 3D structural information from NMR, part 1 -- Application of NOEs and 3JHH-couplings in 3D structure determination -- Development of NMR experiments for determination of long-range J-coupling constants -- Theory – 3D structural information from NMR, part 2 -- Determination of long-range residual dipolar coupling constants -- Chiral alignment media for enantiodiscrimination -- Tensor free RDC calculations -- Overall perspective and conclusions. |
| Record Nr. | UNINA-9910298582103321 |
Hoeck Casper Rønn
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| Cham : , : Springer International Publishing : , : Imprint : Springer, , 2018 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Stereoselective Desymmetrization Methods in the Assembly of Complex Natural Molecules / / by Robert.J Sharpe
| Stereoselective Desymmetrization Methods in the Assembly of Complex Natural Molecules / / by Robert.J Sharpe |
| Autore | Sharpe Robert.J |
| Edizione | [1st ed. 2016.] |
| Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2016 |
| Descrizione fisica | 1 online resource (XXIX, 266 p. 367 illus., 11 illus. in color.) |
| Disciplina | 547.2 |
| Collana | Springer Theses, Recognizing Outstanding Ph.D. Research |
| Soggetto topico |
Organic chemistry
Medicinal chemistry Chemical engineering Organic Chemistry Medicinal Chemistry Industrial Chemistry/Chemical Engineering |
| ISBN | 3-319-39025-2 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Asymmetric Synthesis Of The Aminocyclitol Pactamycin, A Universal Translocation Inhibitor -- Preparation And Biological Evaluation Of Synthetic and Polymer-Encapsulated Congeners of the Antitumor Agent Pactamycin: Insight Into Functional Group Effects and Biological Activity -- Inception and Development of a Global and Local Desymmetrization Approach to the Synthesis of Steroidal Alkaloids: Stereocontrolled Total Synthesis of Paspaline. |
| Record Nr. | UNINA-9910254049803321 |
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Sharpe Robert.J
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| Cham : , : Springer International Publishing : , : Imprint : Springer, , 2016 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Stereoselective Heterocycle Synthesis via Alkene Difunctionalization : Bulky Phosphine Ligands Enable Pd-Catalyzed Arylhalogenation, Arylcyanation and Diarylation / / by David A. Petrone
| Stereoselective Heterocycle Synthesis via Alkene Difunctionalization : Bulky Phosphine Ligands Enable Pd-Catalyzed Arylhalogenation, Arylcyanation and Diarylation / / by David A. Petrone |
| Autore | Petrone David A |
| Edizione | [1st ed. 2018.] |
| Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2018 |
| Descrizione fisica | 1 online resource (392 pages) |
| Disciplina | 547.2 |
| Collana | Springer Theses, Recognizing Outstanding Ph.D. Research |
| Soggetto topico |
Organometallic chemistry
Catalysis Medicinal chemistry Organometallic Chemistry Medicinal Chemistry |
| ISBN | 3-319-77507-3 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Diastereoselective Synthesis of Heterocycles via Intramolecular Pd-Catalyzed Alkene Aryliodination -- Pd-Catalyzed Diastereoselective Carbocyanation Reactions of Chiral N-Allyl Carboxamides and Indoles -- Development of a Pd-Catalyzed Dearomative 1,2-Diarylation of Indoles using Aryl Boron Reagents -- Harnessing Reversible Oxidative Addition: Application of Diiodinated Aromatic Compounds in Aryliodination. |
| Record Nr. | UNINA-9910298594303321 |
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Petrone David A
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| Cham : , : Springer International Publishing : , : Imprint : Springer, , 2018 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Structural Bioinformatics: Applications in Preclinical Drug Discovery Process / / edited by C. Gopi Mohan
| Structural Bioinformatics: Applications in Preclinical Drug Discovery Process / / edited by C. Gopi Mohan |
| Edizione | [1st ed. 2019.] |
| Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2019 |
| Descrizione fisica | 1 online resource (XII, 406 p. 106 illus., 79 illus. in color.) |
| Disciplina |
541.0285
615.19 |
| Collana | Challenges and Advances in Computational Chemistry and Physics |
| Soggetto topico |
Chemoinformatics
Pharmaceutical technology Proteins Bioinformatics Medicinal chemistry Computer Applications in Chemistry Pharmaceutical Sciences/Technology Protein-Ligand Interactions Computational Biology/Bioinformatics Medicinal Chemistry |
| ISBN | 3-030-05282-6 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Free Energy based methods to understand drug resistant mutations -- Structure-based inhibitor design for some multi-targeted drugs and its ADMET profile -- Structure-based drug design in anti-malarial agent identification -- Epigenome - the guide to genomic expression for different diseases -- Structure-based design towards Anti-Alzheimer agents -- Challenges of Structure-based drug design and discovery. |
| Record Nr. | UNINA-9910337929003321 |
| Cham : , : Springer International Publishing : , : Imprint : Springer, , 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Structure and Function of GPCRs / / edited by Guillaume Lebon
| Structure and Function of GPCRs / / edited by Guillaume Lebon |
| Edizione | [1st ed. 2019.] |
| Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2019 |
| Descrizione fisica | 1 online resource (299 pages) |
| Disciplina | 572.6 |
| Collana | Topics in Medicinal Chemistry |
| Soggetto topico |
Medicinal chemistry
Pharmaceutical technology Spectroscopy Medicinal Chemistry Pharmaceutical Sciences/Technology Spectroscopy/Spectrometry |
| ISBN | 3-030-24591-8 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Structures of Non-rhodopsin GPCRs Elucidated Through X-Ray Crystallography -- NMR Spectroscopy for the Characterization of GPCR Energy Landscapes -- Structure and Activation Mechanism of GPCRs -- Structure-Based Discovery of GPCR Ligands from Crystal Structures and Homology Models -- Integration on Ligand and Structure Based Approaches in GPCRs -- Biased Agonist Pharmacochaperones: Small Molecules in the Toolbox for Selectively Modulating GPCR Activity -- Endosomal PTH Receptor Signaling Through cAMP and Its Consequence for Human Medicine -- Structure and Function Studies of GPCRs by Site-Specific Incorporation of Unnatural Amino Acids -- Fluorescent-Based Strategies to Investigate G Protein-Coupled Receptors: Evolution of the Techniques to a Better Understanding -- Modulation of Metabotropic Glutamate Receptors by Orthosteric, Allosteric, and Light-Operated Ligands. . |
| Record Nr. | UNINA-9910349518103321 |
| Cham : , : Springer International Publishing : , : Imprint : Springer, , 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Sulfur Dioxide Insertion Reactions for Organic Synthesis / / by Danqing Zheng, Jie Wu
| Sulfur Dioxide Insertion Reactions for Organic Synthesis / / by Danqing Zheng, Jie Wu |
| Autore | Zheng Danqing |
| Edizione | [1st ed. 2017.] |
| Pubbl/distr/stampa | Singapore : , : Springer Singapore : , : Imprint : Springer, , 2017 |
| Descrizione fisica | 1 online resource (V, 80 p. 73 illus., 5 illus. in color.) |
| Disciplina | 547.2 |
| Collana | SpringerBriefs in Molecular Science |
| Soggetto topico |
Organometallic chemistry
Medicinal chemistry Chemical engineering Organometallic Chemistry Medicinal Chemistry Industrial Chemistry/Chemical Engineering |
| ISBN | 981-10-4202-0 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Introduction -- Sulfur Dioxide Surrogates -- Sulfur Dioxide Insertion Reactions -- Conclusions and Outlook. |
| Record Nr. | UNINA-9910254140603321 |
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Zheng Danqing
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| Singapore : , : Springer Singapore : , : Imprint : Springer, , 2017 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Soggetto topico
-
Medicinal Chemistry
(210)
- Medicinal chemistry (207)
- Organic Chemistry (66)
- Organic chemistry (45)
- Pharmacology (37)