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Biomedical applications of mass spectrometry [[electronic resource] /] / edited by Clarence H. Suelter, J. Throck Watson
| Biomedical applications of mass spectrometry [[electronic resource] /] / edited by Clarence H. Suelter, J. Throck Watson |
| Pubbl/distr/stampa | New York, : Wiley, c1990 |
| Descrizione fisica | 1 online resource (412 p.) |
| Disciplina |
543.65
543.8 |
| Altri autori (Persone) |
SuelterClarence H. <1928->
WatsonJ. Throck |
| Collana | Methods of biochemical analysis |
| Soggetto topico |
Biochemistry
Mass spectrometry |
| ISBN |
1-282-30758-4
9786612307584 0-470-11055-4 0-470-11096-1 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | BIOMEDICAL APPLICATIONS OF MASS SPECTROMETRY; CONTENTS; Abbreviations; Mass Spectrometry: An Introduction; Mass Spectrometry of Carbohydrates; Peptide Sequencing by Mass Spectrometry; Mass spectrometry of Nucleic Acid Components; Mass spectrometry in Pharmacology; Author Index; Subject Index; Cumulative Author Index; Cumulative Subject Index |
| Record Nr. | UNINA-9910830067403321 |
| New York, : Wiley, c1990 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Biomedical applications of mass spectrometry [[electronic resource] /] / edited by Clarence H. Suelter, J. Throck Watson
| Biomedical applications of mass spectrometry [[electronic resource] /] / edited by Clarence H. Suelter, J. Throck Watson |
| Pubbl/distr/stampa | New York, : Wiley, c1990 |
| Descrizione fisica | 1 online resource (412 p.) |
| Disciplina |
543.65
543.8 |
| Altri autori (Persone) |
SuelterClarence H. <1928->
WatsonJ. Throck |
| Collana | Methods of biochemical analysis |
| Soggetto topico |
Biochemistry
Mass spectrometry |
| ISBN |
1-282-30758-4
9786612307584 0-470-11055-4 0-470-11096-1 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | BIOMEDICAL APPLICATIONS OF MASS SPECTROMETRY; CONTENTS; Abbreviations; Mass Spectrometry: An Introduction; Mass Spectrometry of Carbohydrates; Peptide Sequencing by Mass Spectrometry; Mass spectrometry of Nucleic Acid Components; Mass spectrometry in Pharmacology; Author Index; Subject Index; Cumulative Author Index; Cumulative Subject Index |
| Record Nr. | UNINA-9910840580703321 |
| New York, : Wiley, c1990 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Capillary electrophoresis - mass spectrometry (CE-MS) : principles and applications / / edited by Gerhardus de Jong
| Capillary electrophoresis - mass spectrometry (CE-MS) : principles and applications / / edited by Gerhardus de Jong |
| Pubbl/distr/stampa | Weinheim, Germany : , : Wiley-VCH Verlag GmbH & Co. KGaA, , 2016 |
| Descrizione fisica | 1 online resource (421 p.) |
| Disciplina | 543.0871 |
| Soggetto topico |
Capillary electrophoresis
Mass spectrometry |
| ISBN |
3-527-69383-1
3-527-69381-5 3-527-69380-7 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910134854103321 |
| Weinheim, Germany : , : Wiley-VCH Verlag GmbH & Co. KGaA, , 2016 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Capillary Electrophoresis-Mass Spectrometry : Therapeutic Protein Characterization / / edited by James Q. Xia, Lichao Zhang
| Capillary Electrophoresis-Mass Spectrometry : Therapeutic Protein Characterization / / edited by James Q. Xia, Lichao Zhang |
| Edizione | [1st ed. 2016.] |
| Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2016 |
| Descrizione fisica | 1 online resource (IX, 74 p. 28 illus., 21 illus. in color.) |
| Disciplina | 572.6 |
| Soggetto topico |
Proteins
Mass spectrometry Spectroscopy Microscopy Protein Science Mass Spectrometry Spectroscopy and Microscopy |
| ISBN | 3-319-46240-7 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Introduction to Capillary Electrophoresis—Mass Spectrometry -- Coated Capillaries for CE-MS of Therapeutic Protein -- Intact Mass Analysis of Monoclonal Antibodies by Capillary Electrophoresis–Mass Spectrometry -- Separation and Characterization of Proteins and Peptides in Biological Fluids using CE-MS -- Host Cell Protein Analysis using CE-MS -- Antibody PTM Analysis using CE-MS -- Characterization of Intact Therapeutic Proteins and Protein Subunits using CE-MS Platform. |
| Record Nr. | UNINA-9910150449203321 |
| Cham : , : Springer International Publishing : , : Imprint : Springer, , 2016 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Characterization of impurities and degradants using mass spectrometry / / edited by Birendra N. Pramanik, Mike S. Lee, Guodong Chen
| Characterization of impurities and degradants using mass spectrometry / / edited by Birendra N. Pramanik, Mike S. Lee, Guodong Chen |
| Pubbl/distr/stampa | Hoboken : , : Wiley, , 2011 |
| Descrizione fisica | 1 online resource (xxii, 462 pages) : illustrations |
| Disciplina |
615.1
615/.1 |
| Altri autori (Persone) |
PramanikBirendra N. <1944->
LeeMike S. <1960-> ChenGuodong |
| Collana | Wiley Series on Pharmaceutical Science and Biotechnology: Practices, Applications and Methods |
| Soggetto topico |
Drugs - Analysis
Drugs - Spectra Mass spectrometry Contamination (Technology) Public Health Chemistry Techniques, Analytical Investigative Techniques Environment and Public Health Health Care Pharmaceutical Preparations Mass Spectrometry Drug Contamination Health & Biological Sciences Pharmacy, Therapeutics, & Pharmacology |
| ISBN |
1-283-23943-4
9786613239433 0-470-92136-6 0-470-92137-4 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
CHARACTERIZATION OF IMPURITIES AND DEGRADANTS USING MASS SPECTROMETRY; CONTENTS; PREFACE; CONTRIBUTORS; ACRONYMS; PART I: METHODOLOGY; 1. Introduction to Mass Spectrometry; 1.1. History; 1.1.1. Atomic Physics; 1.1.2. Early Applications; 1.1.3. Organic Structural Analysis; 1.1.4. The Biological Mass Spectrometry Revolution; 1.2. Ionization Methods; 1.3. Mass Spectrometer Types; 1.3.1. Magnetic Sector Mass Spectrometers; 1.3.2. Quadrupole Mass Filter and Quadrupole Ion Trap Mass Spectrometers; 1.3.3. Time-of-Flight Mass Spectrometers
1.3.4. Fourier Transform Ion Cyclotron Resonance Mass Spectrometers; 1.3.5. Orbitrap Mass Spectrometers; 1.4. Tandem Mass Spectrometry; 1.4.1. Ion Isolation; 1.4.2. Ion-Molecule Collisions and Collision-Induced Dissociation; 1.4.3. Electron Capture Dissociation and Electron Transfer Dissociation; 1.5. Separation Techniques Coupled to Mass Spectrometry; 1.5.1. Gas Chromatography-Mass Spectrometry; 1.5.2. Liquid Chromatography-Mass Spectrometry; 1.5.3. Capillary Electrophoresis-Mass Spectrometry; 1.5.4. Ion Mobility Spectrometry-Mass Spectrometry; 1.6. Prospects for Mass Spectrometry; References 2. LC Method Development and Strategies; 2.1. Introduction; 2.2. Column, pH, and Solvent Screening; 2.2.1. Resolution: Goal of Separation; 2.2.2. Screening: Systematic Approach to Seeking Selectivity; 2.2.3. Screening Instrumentation and Controlling Software; 2.3. Gradient and Temperature Optimization; 2.4. Orthogonal Screening; 2.4.1. Method Orthogonality; 2.4.2. Selection of Orthogonal Methods; 2.4.3. Impurity Orthogonal Screening; 2.5. High-Efficiency Separation; 2.6. Conclusions; References 3. Rapid Analysis of Drug-Related Substances using Desorption Electrospray Ionization and Direct Analysis in Real Time Ionization Mass Spectrometry; 3.1. Introduction; 3.2. Ionization Apparatus, Mechanisms, and General Performance; 3.2.1. Desorption Electrospray Ionization (DESI); 3.2.2. Direct Analysis in Real Time (DART); 3.3. Drug Analysis in Biological Matrices using DESI and DART; 3.3.1. DESI Application; 3.3.2. DART Application; 3.4. High-Throughput Analysis; 3.5. Chemical Imaging and Profiling; 3.6. Future Perspectives; References; 4. Orbitrap High-Resolution Applications 4.1. Historical Anecdote; 4.2. General Description of Orbitrap Operating Principles; 4.3. The Orbitrap is a "Fourier Transform" Device; 4.4. Performing Experiments in Trapping Devices; 4.4.1. "Raw" HPLC Data Look Like Infusion Data; 4.4.2. How Much Mass Resolution Should Be Used During HPLC; 4.5. Determining Elemental Compositions of "Unknowns" Using an Orbitrap; 4.6. Orbitrap Figures of Merit in Mass Measurement; 4.6.1. Accuracy; 4.6.2. Precision; 4.6.3. Discussion; 4.7. HPLC Orbitrap MS: Accurate Mass Demonstration and Differentiation of Small Molecule Formulas Very Proximate in Mass/Charge Ratio Space |
| Record Nr. | UNINA-9910132377503321 |
| Hoboken : , : Wiley, , 2011 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Characterization of impurities and degradants using mass spectrometry / / edited by Birendra N. Pramanik, Mike S. Lee, Guodong Chen
| Characterization of impurities and degradants using mass spectrometry / / edited by Birendra N. Pramanik, Mike S. Lee, Guodong Chen |
| Pubbl/distr/stampa | Hoboken : , : Wiley, , 2011 |
| Descrizione fisica | 1 online resource (xxii, 462 pages) : illustrations |
| Disciplina |
615.1
615/.1 |
| Altri autori (Persone) |
PramanikBirendra N. <1944->
LeeMike S. <1960-> ChenGuodong |
| Collana | Wiley Series on Pharmaceutical Science and Biotechnology: Practices, Applications and Methods |
| Soggetto topico |
Drugs - Analysis
Drugs - Spectra Mass spectrometry Contamination (Technology) Public Health Chemistry Techniques, Analytical Investigative Techniques Environment and Public Health Health Care Pharmaceutical Preparations Mass Spectrometry Drug Contamination Health & Biological Sciences Pharmacy, Therapeutics, & Pharmacology |
| ISBN |
1-283-23943-4
9786613239433 0-470-92136-6 0-470-92137-4 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
CHARACTERIZATION OF IMPURITIES AND DEGRADANTS USING MASS SPECTROMETRY; CONTENTS; PREFACE; CONTRIBUTORS; ACRONYMS; PART I: METHODOLOGY; 1. Introduction to Mass Spectrometry; 1.1. History; 1.1.1. Atomic Physics; 1.1.2. Early Applications; 1.1.3. Organic Structural Analysis; 1.1.4. The Biological Mass Spectrometry Revolution; 1.2. Ionization Methods; 1.3. Mass Spectrometer Types; 1.3.1. Magnetic Sector Mass Spectrometers; 1.3.2. Quadrupole Mass Filter and Quadrupole Ion Trap Mass Spectrometers; 1.3.3. Time-of-Flight Mass Spectrometers
1.3.4. Fourier Transform Ion Cyclotron Resonance Mass Spectrometers; 1.3.5. Orbitrap Mass Spectrometers; 1.4. Tandem Mass Spectrometry; 1.4.1. Ion Isolation; 1.4.2. Ion-Molecule Collisions and Collision-Induced Dissociation; 1.4.3. Electron Capture Dissociation and Electron Transfer Dissociation; 1.5. Separation Techniques Coupled to Mass Spectrometry; 1.5.1. Gas Chromatography-Mass Spectrometry; 1.5.2. Liquid Chromatography-Mass Spectrometry; 1.5.3. Capillary Electrophoresis-Mass Spectrometry; 1.5.4. Ion Mobility Spectrometry-Mass Spectrometry; 1.6. Prospects for Mass Spectrometry; References 2. LC Method Development and Strategies; 2.1. Introduction; 2.2. Column, pH, and Solvent Screening; 2.2.1. Resolution: Goal of Separation; 2.2.2. Screening: Systematic Approach to Seeking Selectivity; 2.2.3. Screening Instrumentation and Controlling Software; 2.3. Gradient and Temperature Optimization; 2.4. Orthogonal Screening; 2.4.1. Method Orthogonality; 2.4.2. Selection of Orthogonal Methods; 2.4.3. Impurity Orthogonal Screening; 2.5. High-Efficiency Separation; 2.6. Conclusions; References 3. Rapid Analysis of Drug-Related Substances using Desorption Electrospray Ionization and Direct Analysis in Real Time Ionization Mass Spectrometry; 3.1. Introduction; 3.2. Ionization Apparatus, Mechanisms, and General Performance; 3.2.1. Desorption Electrospray Ionization (DESI); 3.2.2. Direct Analysis in Real Time (DART); 3.3. Drug Analysis in Biological Matrices using DESI and DART; 3.3.1. DESI Application; 3.3.2. DART Application; 3.4. High-Throughput Analysis; 3.5. Chemical Imaging and Profiling; 3.6. Future Perspectives; References; 4. Orbitrap High-Resolution Applications 4.1. Historical Anecdote; 4.2. General Description of Orbitrap Operating Principles; 4.3. The Orbitrap is a "Fourier Transform" Device; 4.4. Performing Experiments in Trapping Devices; 4.4.1. "Raw" HPLC Data Look Like Infusion Data; 4.4.2. How Much Mass Resolution Should Be Used During HPLC; 4.5. Determining Elemental Compositions of "Unknowns" Using an Orbitrap; 4.6. Orbitrap Figures of Merit in Mass Measurement; 4.6.1. Accuracy; 4.6.2. Precision; 4.6.3. Discussion; 4.7. HPLC Orbitrap MS: Accurate Mass Demonstration and Differentiation of Small Molecule Formulas Very Proximate in Mass/Charge Ratio Space |
| Record Nr. | UNINA-9910810569103321 |
| Hoboken : , : Wiley, , 2011 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Characterization of Protein Therapeutics using Mass Spectrometry [[electronic resource] /] / edited by Guodong Chen
| Characterization of Protein Therapeutics using Mass Spectrometry [[electronic resource] /] / edited by Guodong Chen |
| Edizione | [1st ed. 2013.] |
| Pubbl/distr/stampa | New York, NY : , : Springer US : , : Imprint : Springer, , 2013 |
| Descrizione fisica | 1 online resource (408 p.) |
| Disciplina |
54
543.65 572.6 599935 |
| Soggetto topico |
Mass spectrometry
Proteins Pharmaceutical technology Biotechnology Human genetics Materials science Mass Spectrometry Protein Science Pharmaceutical Sciences/Technology Human Genetics Characterization and Evaluation of Materials |
| ISBN | 1-4419-7862-3 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Characterization of Protein Therapeutics by Mass Spectrometry: Recent Developments and Future Directions -- The Use of Mass Spectrometry to Characterize the Metabolism of Peptide Therapeutics -- Quantitative Analysis of Biologics Using Mass Spectrometry -- Maximizing Structural Information from Whole Protein Tandem Mass Spectrometry -- Disulfide Linkages of an Albumin Fusion Protein -- Detailed Structural Characterization of Monoclonal Antibodies -- Application of Protein Mass Spectrometry in Impurity and Degradant Characterization -- Mass Spectrometry Methods to Analyze Higher Order Structure of Protein Therapeutics by Chemical Footprinting -- Aglycosylations Alters Protein Conformation in Antibodies Engineered with Specific Effector Functions Using HDX-MS -- Characterizing Biotherapeutic Protein 3D Structures by Electrospray Ion-Mobility Mass Spectrometry -- Oxford University, Characterization of Assemblies of Proteins by Mass Spectrometry. . |
| Record Nr. | UNINA-9910437808403321 |
| New York, NY : , : Springer US : , : Imprint : Springer, , 2013 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Chemical kinetic modeling and mass spectrometric and laser-induced fluorescence measurements of NH₃/N₂O flames [[electronic resource] /] / Demetris T. Venizelos, Rosario C. Sausa
| Chemical kinetic modeling and mass spectrometric and laser-induced fluorescence measurements of NH₃/N₂O flames [[electronic resource] /] / Demetris T. Venizelos, Rosario C. Sausa |
| Autore | Venizelos Demetris T |
| Pubbl/distr/stampa | Aberdeen Proving Ground, MD : , : Army Research Laboratory, , [2002] |
| Descrizione fisica | 1 online resource (x, 18 pages) : illustrations |
| Altri autori (Persone) | SausaRosario C |
| Collana | ARL-TR |
| Soggetto topico |
Reaction mechanisms (Chemistry)
Mass spectrometry Laser spectroscopy |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910699997603321 |
Venizelos Demetris T
|
||
| Aberdeen Proving Ground, MD : , : Army Research Laboratory, , [2002] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Clinical mass spectrometry
| Clinical mass spectrometry |
| Pubbl/distr/stampa | [Amsterdam] : , : Elsevier, , [2016]-[2020] |
| Descrizione fisica | 1 online resource |
| Disciplina | 543.65 |
| Soggetto topico |
Mass spectrometry
Mass Spectrometry Clinical Medicine |
| Soggetto genere / forma |
Periodical
Fulltext Internet Resources. Periodicals. |
| ISSN | 2213-8005 |
| Formato | Materiale a stampa |
| Livello bibliografico | Periodico |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | CMS |
| Record Nr. | UNISA-996284646703316 |
| [Amsterdam] : , : Elsevier, , [2016]-[2020] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. di Salerno | ||
| ||
Clinical mass spectrometry
| Clinical mass spectrometry |
| Pubbl/distr/stampa | [Amsterdam] : , : Elsevier, , [2016]-[2020] |
| Descrizione fisica | 1 online resource |
| Disciplina | 543.65 |
| Soggetto topico |
Mass spectrometry
Mass Spectrometry Clinical Medicine |
| Soggetto genere / forma |
Periodical
Fulltext Internet Resources. Periodicals. |
| ISSN | 2213-8005 |
| Formato | Materiale a stampa |
| Livello bibliografico | Periodico |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | CMS |
| Record Nr. | UNINA-9910249558503321 |
| [Amsterdam] : , : Elsevier, , [2016]-[2020] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Soggetto topico
-
Mass spectrometry
(351)
- Mass Spectrometry (45)
- Gas chromatography (34)
- Drugs - Analysis (20)
- Liquid chromatography (20)