Edizione	[2nd ed.]
Pubbl/distr/stampa	Boca Raton : , : Taylor & Francis, , 2010
Descrizione fisica	XIX, 695 p : il ; 26 cm
Disciplina	543/.84
Altri autori (Persone)	CorradiniDanilo
Collana	Chromatographic science series
Soggetto topico	High performance liquid chromatography Liquid chromatography
Soggetto genere / forma	Electronic books.
ISBN	0-429-11858-9 1-4200-1694-6
Formato	Materiale a stampa
Livello bibliografico	Monografia
Lingua di pubblicazione	eng
Nota di contenuto	part PART I Fundamentals -- chapter 1 Monolithic Stationary Phases in HPLC -- chapter 2 Bonded Stationary Phases -- chapter 3 Micro-HPLC -- chapter 4 Two-DimensionalComprehensive Liquid Chromatography -- chapter 5 Gradient Elution Mode -- chapter 6 Capillary Electromigration Techniques -- chapter 7 HPLC Detectors -- chapter 8 LC-MS Interfaces: State of theArt and Emerging Techniques -- chapter 9 Control and Effectsof Temperature in Analytical HPLC -- chapter 10 Nonlinear Liquid Chromatography -- chapter 11 Displacement Chromatographyin the Separation andCharacterization ofProteins and Peptides -- chapter 12 Field-Flow Fractionation -- chapter 13 Affinity Chromatography -- chapter 14 Ion Chromatography: Modesfor Metal Ions Analysis -- chapter 15 Retention Modelsfor Ions in HPLC -- chapter 16 Polymer HPLC -- part PART II Applications -- chapter 17 HPLC in ChiralPharmaceutical Analysis -- chapter 18 HPLC in Environmental Analysis -- chapter 19 HPLC in Food Analysis -- chapter 20 HPLC in Forensic Sciences.
Record Nr.	UNINA-9910458858003321

Pubbl/distr/stampa	Hoboken, N.J., : John Wiley & Sons, 2013
Descrizione fisica	1 online resource (706 p.)
Disciplina	615.1/901
Altri autori (Persone)	LiWenkui <1964-> ZhangJie <1962-> TseFrancis L. S
Soggetto topico	Drugs - Spectra Drugs - Analysis Mass spectrometry Liquid chromatography
ISBN	1-118-67135-X 1-118-67127-9 1-118-67134-1
Formato	Materiale a stampa
Livello bibliografico	Monografia
Lingua di pubblicazione	eng
Nota di contenuto	pt. I. Overview of LC-MS bioanalysis -- pt. II. Current understanding of LC-MS bioanalysis-related regulations -- pt. III. Best practice in LC-MS bioanalysis -- pt. IV. Representative guidelines and/or experimental protocols of LC-MS bioanalysis.
Record Nr.	UNINA-9910139023203321

Pubbl/distr/stampa	Weinheim, : Wiley-VCH
Descrizione fisica	1 online resource (789 p.)
Disciplina	543.0894 543.84
Altri autori (Persone)	KromidasStavros
Soggetto topico	High performance liquid chromatography - Methodology Liquid chromatography
Soggetto genere / forma	Electronic books.
ISBN	1-281-31169-3 9786611311698 3-527-61197-5 3-527-61199-1
Formato	Materiale a stampa
Livello bibliografico	Monografia
Lingua di pubblicazione	eng
Nota di contenuto	HPLC Made to Measure; Foreword; Preface; Contents; List of Contributors; Structure of the Book; 1 Fundamentals of Optimization; 1.1 Principles of the Optimization of HPLC Illustrated by RP-Chromatography; 1.1.1 Before the First Steps of Optimization; 1.1.2 What Exactly Do We Mean By "Optimization"?; 1.1.3 Improvement of Resolution ("Separate Better"); 1.1.3.1 Principal Possibilities for Improving Resolution; 1.1.3.2 What has the Greatest Effect on Resolution?; 1.1.3.3 Which Sequence of Steps is Most Logical When Attempting an Optimization?; 1.1.3.4 How to Change k, α, and N 1.1.3.4.1 Isocratic Mode1.1.3.4.2 Gradient Mode; 1.1.3.4.3 Acetonitrile or Methanol?; 1.1.4 Testing of the Peak Homogeneity; 1.1.5 Unknown Samples: "How Can I Start?"; Strategies and Concepts; 1.1.5.1 The "Two Days Method"; 1.1.5.2 "The 5-Step Model"; 1.1.6 Shortening of the Run Time ("Faster Separation"); 1.1.7 Improvement of the Sensitivity ("To See More", i.e. Lowering of the Detection Limit); 1.1.8 Economics in HPLC ("Cheaper Separation"); 1.1.9 Final Remarks and Outlook; References; 1.2 Fast Gradient Separations; 1.2.1 Introduction; 1.2.2 Main Part; 1.2.2.1 Theory; 1.2.2.2 Results 1.2.2.2.1 General Relationships1.2.2.2.2 Short Columns, Small Particles; 1.2.2.2.3 An Actual Example; 1.2.2.3 Optimal Operating Conditions and Limits of Currently Available Technology; 1.2.2.4 Problems and Solutions; 1.2.2.4.1 Gradient Delay Volume; 1.2.2.4.2 Detector Sampling Rate and Time Constant; 1.2.2.4.3 Ion Suppression in Mass Spectrometry; References; 1.3 pH and Selectivity in RP-Chromatography; 1.3.1 Introduction; 1.3.2 Main Section; 1.3.2.1 Ionization and pH; 1.3.2.2 Mobile Phase and pH; 1.3.2.2.1 Buffer Capacity 1.3.2.2.2 Changes of pK and pH Value in the Presence of an Organic Solvent1.3.2.3 Buffers; 1.3.2.3.1 Classical HPLC Buffers; 1.3.2.3.2 MS-Compatible pH Control; 1.3.2.4 Influence of the Samples; 1.3.2.4.1 The Sample Type: Acids, Bases, Zwitterions; 1.3.2.4.2 Influence of the Organic Solvent on the Ionization of the Analytes; 1.3.3 Application Example; 1.3.4 Troubleshooting; 1.3.4.1 Reproducibility Problems; 1.3.4.2 Buffer Strength and Solubility; 1.3.4.3 Constant Buffer Concentration; 1.3.5 Summary; References; 1.4 Selecting the Correct pH Value for HPLC; 1.4.1 Introduction 1.4.2 Typical Approaches to pH Selection1.4.3 Initial pH Selection; 1.4.4 Basis of pK(a) Prediction; 1.4.5 Correction of pH Based on Organic Content; 1.4.6 Optimization of Mobile Phase pH Without Chemical Structures; 1.4.7 A Systematic Approach to pH Selection; 1.4.8 An Example - Separation of 1,4-Bis[(2-pyridin-2-ylethyl)thio]butane-2,3-diol from its Impurities; 1.4.9 Troubleshooting Mobile Phase pH; 1.4.10 The Future; 1.4.11 Conclusion; References; 1.5 Optimization of the Evaluation in Chromatography; 1.5.1 Evaluation of Chromatographic Data - An Introduction; 1.5.2 Working Range 1.5.3 Internal Standard
Record Nr.	UNINA-9910146269003321

Autore	Lim, C. K.
Pubbl/distr/stampa	Oxford [Oxfordshire] : IRL Press, c1986
Descrizione fisica	xviii, 333 p. : ill. ; 24 cm
Disciplina	547.1
Collana	The Practical approach series
Soggetto topico	Biochemistry Organic Chemistry High performance liquid chromatography Liquid chromatography
ISBN	0947946772
Formato	Materiale a stampa
Livello bibliografico	Monografia
Lingua di pubblicazione	eng
Record Nr.	UNISALENTO-991003491379707536

Autore	Niessen W. M. A (Wilfried M. A.), <1956->
Pubbl/distr/stampa	Hoboken, New Jersey : , : Wiley, , 2017
Descrizione fisica	1 online resource (412 pages) : illustrations, tables
Disciplina	543/.65
Collana	Wiley Series on Mass Spectrometry
Soggetto topico	Tandem mass spectrometry Liquid chromatography Drugs - Analysis Pesticides - Analysis
ISBN	1-119-29424-X 1-119-29426-6
Formato	Materiale a stampa
Livello bibliografico	Monografia
Lingua di pubblicazione	eng
Nota di contenuto	Introduction to LC-MS technology -- Interpretation of mass spectra -- Fragmentation of even-electron ions -- Fragmentation of drugs and pesticides -- Identification strategies.
Record Nr.	UNINA-9910158598203321