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Trends in immunology
| Trends in immunology |
| Pubbl/distr/stampa | [Oxford, U. K.], : Elsevier Science Ltd., c2001- |
| Disciplina | 571.96 |
| Soggetto topico |
Immunology
Allergy and Immunology Immunologie - Périodiques |
| ISSN | 1471-4981 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Periodico |
| Lingua di pubblicazione | eng |
| Record Nr. | UNISA-996218692103316 |
| [Oxford, U. K.], : Elsevier Science Ltd., c2001- | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. di Salerno | ||
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Trichloroethylene: Toxicity and Health Risks [[electronic resource] /] / edited by Kathleen M. Gilbert, Sarah J. Blossom
| Trichloroethylene: Toxicity and Health Risks [[electronic resource] /] / edited by Kathleen M. Gilbert, Sarah J. Blossom |
| Autore | Gilbert Kathleen M |
| Edizione | [1st ed. 2014.] |
| Pubbl/distr/stampa | London : , : Springer London : , : Imprint : Springer, , 2014 |
| Descrizione fisica | 1 online resource (249 p.) |
| Disciplina | 615.902 |
| Collana | Molecular and Integrative Toxicology |
| Soggetto topico |
Pharmacology
Epidemiology Molecular biology Immunology Medical biochemistry Environmental health Pharmacology/Toxicology Molecular Medicine Medical Biochemistry Environmental Health |
| ISBN | 1-4471-6311-7 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | History of TCE -- Trichloroethylene and autoimmunity in human and animal.-Hypersensitivity Dermatitis and Hepatitis -- Trichloroethylene-induced oxidative stress and autoimmunity.-Brain and Behavioral Changes in Rodent Models -- Role of Trichloroethylene in Parkinson’s disease -- Neuroimmune effects of developmental TCE exposure -- Environmental sensitivity to trichloroethylene (TCE) in the developing heart -- Trichloroethylene and Cancer -- Epigenetic Alterations Due to Trichloroethylene -- Mathematical Modeling and Trichloroethylene . |
| Record Nr. | UNINA-9910298351803321 |
Gilbert Kathleen M
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| London : , : Springer London : , : Imprint : Springer, , 2014 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Tryptophan Metabolism: Implications for Biological Processes, Health and Disease [[electronic resource] /] / edited by Atilla Engin, Ayse Basak Engin
| Tryptophan Metabolism: Implications for Biological Processes, Health and Disease [[electronic resource] /] / edited by Atilla Engin, Ayse Basak Engin |
| Edizione | [1st ed. 2015.] |
| Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Humana, , 2015 |
| Descrizione fisica | 1 online resource (385 p.) |
| Disciplina |
610
611.01816 615 616.39 616079 |
| Collana | Molecular and Integrative Toxicology |
| Soggetto topico |
Pharmacology
Molecular biology Metabolic diseases Immunology Medicine Pharmacology/Toxicology Molecular Medicine Metabolic Diseases Biomedicine, general |
| ISBN | 3-319-15630-6 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | TRYPTOPHAN RELATED SIGNALING MOLECULES: TARGETS AND FUNCTIONS -- TRYPTOPHAN AND CELL DEATH -- TRYPTOPHAN AND NITRIC OXIDE IN ALLERGY.-Tryptophan metabolites: A microbial perspective -- THE ROLE OF L-TRYPTOPHAN KYNURENINE PATHWAY METABOLISM IN VARIOUS INFECTIOUS DISEASES: FOCUS ON INDOLEAMINE 2,3-DIOXYGENASE 1 -- EVALUATION OF TRYPTOPHAN METABOLISM IN CHRONIC IMMUNE ACTIVATION -- DIABETES AND TRYPTOPHAN METABOLISM -- 3-HYDROXYKYNURENIC ACID AND TYPE 2 DIABETES: IMPLICATIONS FOR AGING, OBESITY, DEPRESSION, PARKINSON’S DISEASE AND SCHIZOPHRENIA -- THERAPEUTICAL IMPLICATIONS OF MELATONIN IN ALZHEIMER´S AND PARKINSON´S DISEASES -- TRYPTOPHAN METABOLISM AND SLEEP -- TRYPTOPHAN IN MOLECULAR HEMATOPOIESIS -- NIGHT-SHIFTS AND MELATONIN: RELEVANCE TO AGE AND BREAST CANCER -- CHEMOTHERAPEUTIC AGENTS IN CANCER TREATMENT AND TRYPTOPHAN METABOLISM.-INDOLEAMINE 2,3-DIOXYGENASE-COMPETENT REGULATORY DENDRITIC CELLS AND THEIR ROLE IN ALLOIMMUNE REGULATION AND TRANSPLANT IMMUNE TOLERANCE -- WINE FLAVOR AND TRYPTOPHAN . |
| Record Nr. | UNINA-9910298299403321 |
| Cham : , : Springer International Publishing : , : Imprint : Humana, , 2015 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Tuberculosis Host-Pathogen Interactions [[electronic resource] /] / edited by Jeffrey D. Cirillo, Ying Kong
| Tuberculosis Host-Pathogen Interactions [[electronic resource] /] / edited by Jeffrey D. Cirillo, Ying Kong |
| Edizione | [1st ed. 2019.] |
| Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2019 |
| Descrizione fisica | 1 online resource (VIII, 255 p. 33 illus., 32 illus. in color.) |
| Disciplina | 616.9041 |
| Soggetto topico |
Medical microbiology
Immunology Communicable diseases Medical Microbiology Infectious Diseases |
| ISBN | 3-030-25381-3 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | 1.Cell Wall Biosynthesis and Latency During Tuberculosis Infections -- 2. The Silent Plague: Regulation of Latent Tuberculosis Infections -- 3. Trehalose Dimycolate (Cord Factor) as a Contributing Factor to Tuberculosis Pathogenesis -- 4. Role of Myeloid-derived Suppressor Cells and Regulatory T-cells in the Tuberculous Granuloma -- 5. Interactions of Mycobacterium tuberculosis with Human Mesenchymal Stem Cells -- 6. Role of Mycobacterium tuberculosis PE and PPE proteins in pathogen-host interactions -- 7. Co-Infection with TB and HIV: Converging Epidemics, Clinical Challenges, and Microbial Synergy -- 8. Optical In Vivo Imaging in Tuberculosis Research -- 9. Mycobacteria Infection and Lipid Droplets – Host and Pathogen Stealing, Sharing and Storing Fat -- 10. Potential Immunology, Transcriptomics and Epigenomic Prediction Tools of the Future to Improve Tuberculosis Control. |
| Record Nr. | UNINA-9910349443603321 |
| Cham : , : Springer International Publishing : , : Imprint : Springer, , 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Tumor Ablation [[electronic resource] ] : Effects on Systemic and Local Anti-Tumor Immunity and on Other Tumor-Microenvironment Interactions / / edited by Yona Keisari
| Tumor Ablation [[electronic resource] ] : Effects on Systemic and Local Anti-Tumor Immunity and on Other Tumor-Microenvironment Interactions / / edited by Yona Keisari |
| Edizione | [1st ed. 2013.] |
| Pubbl/distr/stampa | Dordrecht : , : Springer Netherlands : , : Imprint : Springer, , 2013 |
| Descrizione fisica | 1 online resource (160 p.) |
| Disciplina | 616.9940632 |
| Collana | The Tumor Microenvironment |
| Soggetto topico |
Medicine
Cancer research Oncology Immunology Radiotherapy Biomedicine, general Cancer Research Oncology |
| ISBN |
1-283-63399-X
9786613946447 94-007-4694-6 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Preface; Contents; Chapter 1 Effect of Chemotherapy on the Tumor Microenvironment and Anti-tumor Immunity; 1.1 Introduction; 1.2 Mechanisms of Cell Death Induced by Anti-cancer Therapy; 1.2.1 Apoptosis; 1.2.2 Non-apoptotic Cell Death; 1.2.3 Morphological vs Functional Classification of Cell Death; 1.3 Immunogenicity of Cell Death; 1.4 Biochemical Features of Immunogenic Cell Death; 1.4.1 Calreticulin Exposure; 1.4.2 Heat Shock Proteins (HSPs); 1.4.3 HMGB1 and TLR Interactions; 1.4.4 ATP Release and Activation of the NLRP3 Inflammasome; 1.4.5 Autophagy-Dependent Immune Responses
1.5 Effects of Chemotherapy on the Immune System1.5.1 Immune-Suppressive Effects; 1.5.1.1 Lymphopenia; 1.5.1.2 Non-immunogenic Cell Death; 1.5.2 Immune-Stimulatory Effects; 1.5.2.1 Enhanced Antigen Delivery and Presentation; 1.5.2.2 Homeostatic Proliferation; 1.5.2.3 Regulatory T Cells; 1.5.2.4 Myeloid Derived Suppressor Cells (MDSCs); 1.5.2.5 DNA-Damage Response and Activation of the Innate Immune System; 1.5.2.6 Gemcitabine; 1.5.2.7 5-Fluorouracil (5FU); 1.5.3 Immune-Modulatory Effects of Targeted Agents; 1.5.3.1 Imatinib; 1.5.3.2 Sunitinib and Sorafenib; 1.6 Conclusion; References Chapter 2 Hyperthermia, the Tumor Microenvironment and Immunity2.1 Introduction; 2.2 Hyperthermia; 2.2.1 Fever Range Heating (FRH); 2.2.2 Hyperthermia Range Heating; 2.2.3 Ablation Range Hyperthermia; 2.3 Conclusions; References; Chapter 3 Radiofrequency Ablation in Cancer Therapy: Tuning in to in situ Tumor Vaccines; 3.1 Introduction; 3.2 RFA Techniques/Parameters and Tumor Cell Death; 3.2.1 Direct Effects; 3.2.2 Indirect Effects; 3.3 Release of Immune-Mediating Factors and `Immunogenic' Cell Death; 3.3.1 Release of Tumor-Antigens; 3.3.2 Release of Immune Stimulating Mediators 3.4 Induction of Immune Responses by RFA: The Tumor Microenvironment3.4.1 Antigen Presentation after Radio Frequency Ablation; 3.4.2 Immunity after Radiofrequency Ablation; 3.4.3 Regulation after Radiofrequency Ablation; 3.5 RFA Combinational Strategies; 3.5.1 Tumor Cytotoxicity; 3.5.2 Immunotherapy; 3.5.2.1 Stimulation of Antigen Presentation; 3.5.2.2 Stimulation of T Cell Reactivity; 3.6 Conclusions and Future Perspective; References; Chapter 4 High Intensity Focused Ultrasound (HIFU) Ablation; 4.1 History of HIFU Tumor Ablation; 4.2 Physical Principles of HIFU Ablation 4.3 Technical Aspects of HIFU Ablation4.4 Direct Thermal and Non-thermal Effects on the Tumor; 4.5 Thermal Effects on Tumor Vasculature; 4.6 Indirect Effects on the Tumor; 4.7 HIFU-Induced Antitumor Immune Response; 4.8 Conclusions; References; Chapter 5 The Interrelationship Between Cryoablation, the Immune Response and the Tumor Microenvironment: Stimulatory and Suppressive Effects; 5.1 Introduction; 5.2 Clinical Use of Cryoablation in Cancer; 5.3 Anecdotal Evidence of Immune Response to Cryoablation; 5.4 How Does Cryoablation Kill Tumors?; 5.4.1 Direct Cellular Injury 5.4.2 Indirect Cellular Injury |
| Record Nr. | UNINA-9910437616203321 |
| Dordrecht : , : Springer Netherlands : , : Imprint : Springer, , 2013 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Tumor Immune Microenvironment in Cancer Progression and Cancer Therapy [[electronic resource] /] / edited by Pawel Kalinski
| Tumor Immune Microenvironment in Cancer Progression and Cancer Therapy [[electronic resource] /] / edited by Pawel Kalinski |
| Edizione | [1st ed. 2017.] |
| Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2017 |
| Descrizione fisica | 1 online resource (XIV, 264 p. 47 illus., 43 illus. in color.) |
| Disciplina | 616.994079 |
| Collana | Advances in Experimental Medicine and Biology |
| Soggetto topico |
Cancer research
Oncology Immunology Molecular biology Cancer Research Oncology Molecular Medicine |
| ISBN | 3-319-67577-X |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Part 1. Interplay Between Tumor Cells, Stroma and Inflammatory Infiltrate in Regulating Tumor Micro-Environment -- Tumor Immuno-Environment in Cancer Progression and Therapy -- Cancer Immunotherapy Targets Based on Understanding the T Cell-Inflamed Versus Non-T Cell-Inflamed Tumor Microenvironment -- Regulation of CTL Infiltration Within the Tumor Microenvironment -- The Role of Tumor Microenvironment in Cancer Immunotherapy -- Part 2. Mediators of Tumor Microenvironment -- Immunogenic and Non-Immunogenic Cell Death in the Tumor Microenvironment -- Exosomes in Cancer: Another Mechanism of Tumor-Induced Immune Suppression -- Chemo-immunotherapy: Impact of Indoleamine 2,3-dioxygenase in Defining Immunogenic versus Tolerogenic Cell Death in the Tumor Microenvironment -- Targeting Myeloid-Derived Suppressor Cells in Cancer -- Tryptophan catabolism and cancer immunotherapy targeting IDO mediated immune Suppression -- Part 3. Emerging Targets and Technologies of Modulation of Tumor Microenvironment -- Tumor Microenvironment in Cancer Progression and Therapy -- The Role of the Immune System and Immunoregulatory Mechanisms Relevant to Melanoma -- Oncolytic Virotherapy and the Tumor Microenvironment -- The Impact of Housing Temperature Induced Chronic Stress on Preclinical Mouse Tumor Models and Therapeutic Responses: An Important Role for the Nervous Role for the Nervous System -- (Immuno)therapeutic Targeting of Tumor-Associated Blood Vessels -- Adaptive Resistance to Cancer Immunotherapy -- Imaging the Tumor Microenvironment. |
| Record Nr. | UNINA-9910253958003321 |
| Cham : , : Springer International Publishing : , : Imprint : Springer, , 2017 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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The Tumor Immunoenvironment [[electronic resource] /] / edited by Michael R Shurin, Viktor Umansky, Anatoli Malyguine
| The Tumor Immunoenvironment [[electronic resource] /] / edited by Michael R Shurin, Viktor Umansky, Anatoli Malyguine |
| Edizione | [1st ed. 2013.] |
| Pubbl/distr/stampa | Dordrecht : , : Springer Netherlands : , : Imprint : Springer, , 2013 |
| Descrizione fisica | 1 online resource (745 p.) |
| Disciplina |
616.99
616.994079 |
| Soggetto topico |
Cancer research
Oncology Immunology Life sciences Medicine Cancer Research Oncology Life Sciences, general Biomedicine, general |
| ISBN | 94-007-6217-8 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Preface -- Introduction -- Role of the immunological environment in cancer initiation, development and progression -- Part I Tumor Microenvironment and Immunoenvironment -- The metastatic microenvironment -- Tumor infiltration by immune cells: pathologic evaluation and a clinical significance -- Immunologic interpretation of cancer biology: impact on clinical outcome -- Part II Developmental Characteristics of the Tumor ImmunoEnvironment -- Development of antitumor cellular immunity -- The versatile world of inflammatory chemokines in cancer.-Inflammation, Tumor Progression, and Immune Suppression -- Pleiotropic and differential functions of IL-1a and IL-1b shape the tumor microenvironment and affect the outcome of malignancies -- Impact of obesity and aging on the tumor immunoenvironment -- Part III Tumor Escape from Immune Recognition -- MHC class I antigens and the tumor microenvironment -- Tumor-produced immune regulating factors -- Roles of signaling pathways in cancer cells and immune cells in generation of immunosuppressive tumor-associated microenvironments.- T cell malfunction in the tumor environment -- Signaling of tumor-induced immunosuppression of dendritic cells -- Tumor microenvironment may shape the function and phenotype of NK cells through the induction of split anergy and generation of regulatory NK cells -- Part IV Immune Regulators in the Tumor ImmunoEnvironment -- The role of myeloid-derived suppressor cells in cancer -- Macrophage differentiation and activation states in the tumor microenvironment -- Dendritic cells and cancer: development, dysfunction and therapeutic targets -- The role of tumor-associated neutrophils in cancer -- Mast cell modulation of the tumor microenvironment -- Regulatory T cells in patients with cancer -- Tumor-evoked regulatory B cells as important mediators of cancer escape -- Part V Tumor Escape and Cancer Immunotherapy -- Cancer immunotherapy: Overview in brief -- Programming of MDSC: New opportunities for targeted therapy -- Therapeutic targeting regulatory T cells in tumor.-ChemoImmunoModulation: Focus on myeloid regulatory cells -- Combining vaccines with therapies that render tumor cells more susceptible to immune mediated killing -- Prophylactic Cancer Vaccines -- Part VI Analyzing Immune Responses in Cancer -- Approaches to Immunologic Monitoring of Clinical Trials -- Evaluation of the tumor immunoenvironment in clinical trials -- Analysis of Myeloid-derived Suppressor Cells in Patients with Cancer -- When results of T cell immune monitoring match or do not match clinical outcomes of tumor vaccine trials - what more could and should we measure? |
| Record Nr. | UNINA-9910437855403321 |
| Dordrecht : , : Springer Netherlands : , : Imprint : Springer, , 2013 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Tumor Microenvironment [[electronic resource] /] / edited by Peter P. Lee, Francesco M. Marincola
| Tumor Microenvironment [[electronic resource] /] / edited by Peter P. Lee, Francesco M. Marincola |
| Edizione | [1st ed. 2020.] |
| Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2020 |
| Descrizione fisica | 1 online resource (XXIV, 326 p. 61 illus., 56 illus. in color.) |
| Disciplina | 616.994079 |
| Collana | Cancer Treatment and Research |
| Soggetto topico |
Oncology
Immunology Oncology |
| ISBN | 3-030-38862-X |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Preface -- Part I: Imaging of tumor microenvironment, In vivo Imaging -- New technologies to image tumors -- Part II: Immune landscapes and their biology, Systemic correlates of the tumor microenvironment -- Adaptive immunity and the tumor microenvironment -- The biology of immune active cancers and their regulatory mechanisms -- The biology of immune excluded cancers -- Immunoscore -- Part III: The tumor microenvironment and therapy, The Immune Landscape in Women Cancers -- Translational biomarkers, combination therapies and their relationship with immune landscapes -- Effects of radiation on the tumor microenvironment -- Challenges of CAR T cell therapy for solid tumors. |
| Record Nr. | UNINA-9910383832303321 |
| Cham : , : Springer International Publishing : , : Imprint : Springer, , 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Tumor Microenvironment [[electronic resource] ] : The Main Driver of Metabolic Adaptation / / edited by Jacinta Serpa
| Tumor Microenvironment [[electronic resource] ] : The Main Driver of Metabolic Adaptation / / edited by Jacinta Serpa |
| Edizione | [1st ed. 2020.] |
| Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2020 |
| Descrizione fisica | 1 online resource (VII, 443 p. 63 illus., 61 illus. in color.) |
| Disciplina | 616.99407 |
| Collana | Advances in Experimental Medicine and Biology |
| Soggetto topico |
Cancer research
Molecular biology Human genetics Immunology Human physiology Cell biology Cancer Research Molecular Medicine Human Genetics Human Physiology Cell Biology |
| ISBN | 3-030-34025-2 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Preface -- Tumor microenvironment a job of several holders -- Tumor microenvironment- a selective pressure boosting cancer -- Lactate and lactate transporters as key players in the maintenance of the Warburg effect -- Section 1. Adaptive metabolic features are sustained by tumor microenvironment -- Recycling the interspecific relations with epithelial cells: bacteria and cancer metabolic symbiosis -- Gut microbiota and cancer of the host: colliding interests -- Metabolic plasticity of tumor cells: how they do adapt to food deprivation -- Multifaceted oncogenic role of adipocytes in the tumour microenvironment -- Endothelial cells (ECs) metabolism a valuable piece to disentangle cancer biology -- Monocytes and macrophages in cancer: unsuspected roles -- Section 2. Microenvironment and metabolic signalling- the way cancer cells know how to survive.-: Wnt signaling: paths for cancer progression -- Microenvironment driven metabolic adaptation in melanoma -- Metabolic reprogramming and signaling to chromatin modifications in tumorigenesis -- Inflammatory microenvironment modulation of alternative splicing in cancer: a way to adapt -- The bone marrow niche - the tumor microenvironment that ensures leukemia progression -- Section 3. Metabolic fitness and therapy response in cancer -- Exploiting cancer cells metabolic adaptability to enhance therapy response in cancer -- The metabolic remodelling in lung cancer and its putative consequence in therapy response -- Hydrogen sulfide metabolism and signaling in the tumor microenvironment -- Using metabolic adaptation to design new drugs -- Metabolomics- a new way of screening cancer -- NMR as a tool for metabolomics -- Section 5. Animal models- addressing cancer microenvironment -- Animal models to study cancer and its microenvironment -- Modulating the metabolic phenotype of cancer microenvironment -- Modeling of Solid-tumor Microenvironment in Zebrafish (Danio Rerio) Larvae -- Section 6. In vitro and ex vivo cancer models -- In vitro and ex vivo models- the tumor microenvironment in a flask -- Index. |
| Record Nr. | UNINA-9910409683903321 |
| Cham : , : Springer International Publishing : , : Imprint : Springer, , 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Tumor Microenvironment [[electronic resource] ] : Study Protocols / / edited by Constantinos Koumenis, Lisa M. Coussens, Amato Giaccia, Ester Hammond
| Tumor Microenvironment [[electronic resource] ] : Study Protocols / / edited by Constantinos Koumenis, Lisa M. Coussens, Amato Giaccia, Ester Hammond |
| Edizione | [1st ed. 2016.] |
| Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2016 |
| Descrizione fisica | 1 online resource (VIII, 297 p. 85 illus., 64 illus. in color.) |
| Disciplina | 616.994071 |
| Collana | Advances in Experimental Medicine and Biology |
| Soggetto topico |
Cancer research
Molecular biology Immunology Cancer Research Molecular Medicine |
| ISBN | 3-319-26666-7 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | 1.Staining against phospho-H2AX (γ-H2AX) as a marker for DNA damage and genomic instability in cancer tissues and cells -- 2.Measuring DNA replication rates in hypoxic conditions -- 3.Isolation of Proteins on Nascent DNA in hypoxia and reoxygenation conditions -- 4.In vivo interrogation of the hypoxic transcriptome of solid tumors: optimizing hypoxic probe labelling with Laser-Capture Microdissection for isolation of high-quality RNA for deep sequencing analysis -- 5.Gas chromatography coupled to mass spectrometry (GC-MS) to study metabolism in cultured cells -- 6.Probing Cancer Cell Metabolism using NMR Spectroscopy -- 7.Measuring the Impact of Microenvironmental Conditions on Mitochondrial Dehydrogenases Activity in Cultured Cells -- 8.Measuring Autophagy in the Context of Cancer -- 9.Methods for studying autophagy within the tumor microenvironment -- 10.Using 3 Dimensional Culture (Spheroids) as an in vitro Model of Tumour Hypoxia -- 11.Isolation of Glioma Initiating Cells for Biological Study -- 12.Isolation of mouse and human tumor associated macrophages -- 13.Mouse models of brain metastasis for unravelling tumour progression -- 14.Quantification of lung metastases from in vivo mouse models -- 15.A multimodal data analysis approach for targeted drug discovery involving topological data analysis (TDA) -- 16.Efficient protocol for the identification of hypoxic cell radiosensitisers. |
| Record Nr. | UNINA-9910253873803321 |
| Cham : , : Springer International Publishing : , : Imprint : Springer, , 2016 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Soggetto topico
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Immunology
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