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Tumor Microenvironment [[electronic resource] ] : The Main Driver of Metabolic Adaptation / / edited by Jacinta Serpa
| Tumor Microenvironment [[electronic resource] ] : The Main Driver of Metabolic Adaptation / / edited by Jacinta Serpa |
| Edizione | [1st ed. 2020.] |
| Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2020 |
| Descrizione fisica | 1 online resource (VII, 443 p. 63 illus., 61 illus. in color.) |
| Disciplina | 616.99407 |
| Collana | Advances in Experimental Medicine and Biology |
| Soggetto topico |
Cancer research
Molecular biology Human genetics Immunology Human physiology Cell biology Cancer Research Molecular Medicine Human Genetics Human Physiology Cell Biology |
| ISBN | 3-030-34025-2 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Preface -- Tumor microenvironment a job of several holders -- Tumor microenvironment- a selective pressure boosting cancer -- Lactate and lactate transporters as key players in the maintenance of the Warburg effect -- Section 1. Adaptive metabolic features are sustained by tumor microenvironment -- Recycling the interspecific relations with epithelial cells: bacteria and cancer metabolic symbiosis -- Gut microbiota and cancer of the host: colliding interests -- Metabolic plasticity of tumor cells: how they do adapt to food deprivation -- Multifaceted oncogenic role of adipocytes in the tumour microenvironment -- Endothelial cells (ECs) metabolism a valuable piece to disentangle cancer biology -- Monocytes and macrophages in cancer: unsuspected roles -- Section 2. Microenvironment and metabolic signalling- the way cancer cells know how to survive.-: Wnt signaling: paths for cancer progression -- Microenvironment driven metabolic adaptation in melanoma -- Metabolic reprogramming and signaling to chromatin modifications in tumorigenesis -- Inflammatory microenvironment modulation of alternative splicing in cancer: a way to adapt -- The bone marrow niche - the tumor microenvironment that ensures leukemia progression -- Section 3. Metabolic fitness and therapy response in cancer -- Exploiting cancer cells metabolic adaptability to enhance therapy response in cancer -- The metabolic remodelling in lung cancer and its putative consequence in therapy response -- Hydrogen sulfide metabolism and signaling in the tumor microenvironment -- Using metabolic adaptation to design new drugs -- Metabolomics- a new way of screening cancer -- NMR as a tool for metabolomics -- Section 5. Animal models- addressing cancer microenvironment -- Animal models to study cancer and its microenvironment -- Modulating the metabolic phenotype of cancer microenvironment -- Modeling of Solid-tumor Microenvironment in Zebrafish (Danio Rerio) Larvae -- Section 6. In vitro and ex vivo cancer models -- In vitro and ex vivo models- the tumor microenvironment in a flask -- Index. |
| Record Nr. | UNINA-9910409683903321 |
| Cham : , : Springer International Publishing : , : Imprint : Springer, , 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Tumor Microenvironment [[electronic resource] ] : Study Protocols / / edited by Constantinos Koumenis, Lisa M. Coussens, Amato Giaccia, Ester Hammond
| Tumor Microenvironment [[electronic resource] ] : Study Protocols / / edited by Constantinos Koumenis, Lisa M. Coussens, Amato Giaccia, Ester Hammond |
| Edizione | [1st ed. 2016.] |
| Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2016 |
| Descrizione fisica | 1 online resource (VIII, 297 p. 85 illus., 64 illus. in color.) |
| Disciplina | 616.994071 |
| Collana | Advances in Experimental Medicine and Biology |
| Soggetto topico |
Cancer research
Molecular biology Immunology Cancer Research Molecular Medicine |
| ISBN | 3-319-26666-7 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | 1.Staining against phospho-H2AX (γ-H2AX) as a marker for DNA damage and genomic instability in cancer tissues and cells -- 2.Measuring DNA replication rates in hypoxic conditions -- 3.Isolation of Proteins on Nascent DNA in hypoxia and reoxygenation conditions -- 4.In vivo interrogation of the hypoxic transcriptome of solid tumors: optimizing hypoxic probe labelling with Laser-Capture Microdissection for isolation of high-quality RNA for deep sequencing analysis -- 5.Gas chromatography coupled to mass spectrometry (GC-MS) to study metabolism in cultured cells -- 6.Probing Cancer Cell Metabolism using NMR Spectroscopy -- 7.Measuring the Impact of Microenvironmental Conditions on Mitochondrial Dehydrogenases Activity in Cultured Cells -- 8.Measuring Autophagy in the Context of Cancer -- 9.Methods for studying autophagy within the tumor microenvironment -- 10.Using 3 Dimensional Culture (Spheroids) as an in vitro Model of Tumour Hypoxia -- 11.Isolation of Glioma Initiating Cells for Biological Study -- 12.Isolation of mouse and human tumor associated macrophages -- 13.Mouse models of brain metastasis for unravelling tumour progression -- 14.Quantification of lung metastases from in vivo mouse models -- 15.A multimodal data analysis approach for targeted drug discovery involving topological data analysis (TDA) -- 16.Efficient protocol for the identification of hypoxic cell radiosensitisers. |
| Record Nr. | UNINA-9910253873803321 |
| Cham : , : Springer International Publishing : , : Imprint : Springer, , 2016 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Tumor Microenvironment and Cellular Stress [[electronic resource] ] : Signaling, Metabolism, Imaging, and Therapeutic Targets / / edited by Constantinos Koumenis, Ester Hammond, Amato Giaccia
| Tumor Microenvironment and Cellular Stress [[electronic resource] ] : Signaling, Metabolism, Imaging, and Therapeutic Targets / / edited by Constantinos Koumenis, Ester Hammond, Amato Giaccia |
| Edizione | [1st ed. 2014.] |
| Pubbl/distr/stampa | New York, NY : , : Springer New York : , : Imprint : Springer, , 2014 |
| Descrizione fisica | 1 online resource (293 p.) |
| Disciplina | 616.994 |
| Collana | Advances in Experimental Medicine and Biology |
| Soggetto topico |
Cancer research
Immunology Human physiology Medical microbiology Cancer Research Human Physiology Medical Microbiology |
| ISBN | 1-4614-5915-X |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Introduction -- Hypoxia and metabolism in cancer -- Hypoxia and Regulation of Cancer Cell Stemness -- Hypoxia-mediated metastasis -- Escape Mechanisms from Antiangiogenic Therapy: An Immune Cell’s Perspective -- Hypoxic VDAC1: a potential mitochondrial marker for cancer therapy -- Hypoxia directed drug strategies to target the tumor microenvironment -- Radiotherapy and the Tumor Microenvironment: Mutual Influence and Clinical Implications -- Autophagy and cell death to target cancer cells: exploiting synthetic lethality as cancer therapeutic -- Intratumoral Hypoxia as the Genesis of Genetic Instability and Clinical Prognosis in Prostate Cancer -- miR-210: Fine-Tuning the Hypoxic Response -- The role of complement in tumor growth -- Imaging angiogenesis, inflammation and metastasis in the tumor microenvironment with magnetic resonance imaging -- Index. |
| Record Nr. | UNINA-9910298328603321 |
| New York, NY : , : Springer New York : , : Imprint : Springer, , 2014 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Tumor Necrosis Factor / Cachectin and Related Cytokines : : International Conference on Tumor Necrosis Factor and Related Cytotoxins, Heidelberg, September 1987 / / editors, B. Bonavida, G.E. Gifford, H. Kirchner, L.J. Old
| Tumor Necrosis Factor / Cachectin and Related Cytokines : : International Conference on Tumor Necrosis Factor and Related Cytotoxins, Heidelberg, September 1987 / / editors, B. Bonavida, G.E. Gifford, H. Kirchner, L.J. Old |
| Autore | Bonavida B |
| Pubbl/distr/stampa | Basel : , : S. Karger, , 1988 |
| Descrizione fisica | 1 online resource (VIII + 276 pages) : : 78 figures, 36 tables |
| Disciplina | 616.99/2061 |
| Altri autori (Persone) | BonavidaBenjamin |
| Soggetto topico |
Oncology
Immunology Biochemistry Biology for Physicians Immunobiology Microbiology Molecular Biology |
| ISBN | 3-318-05219-1 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910149635203321 |
Bonavida B
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| Basel : , : S. Karger, , 1988 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Tumor Necrosis Factor: Molecular and Cellular Biology and Clinical Relevance : : 4th International Conference on Tumor Necrosis Factor and Related Cytokines, Veldhoven, May 1992 / / editors, W. Fiers, W.A. Buurman
| Tumor Necrosis Factor: Molecular and Cellular Biology and Clinical Relevance : : 4th International Conference on Tumor Necrosis Factor and Related Cytokines, Veldhoven, May 1992 / / editors, W. Fiers, W.A. Buurman |
| Autore | Fiers W |
| Pubbl/distr/stampa | Basel : , : S. Karger, , 1993 |
| Descrizione fisica | 1 online resource (X + 256 pages) : : 62 figures, 1 in color, 32 tables |
| Disciplina | 616.07/9 |
| Altri autori (Persone) |
FiersWalter
BuurmanWim A |
| Soggetto topico |
Immunology
Oncology Biochemistry Infectious Diseases Molecular Biology Pathology Pharmacology Toxicology |
| ISBN | 3-318-05220-5 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Tumor Necrosis Factor |
| Record Nr. | UNINA-9910149635103321 |
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Fiers W
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| Basel : , : S. Karger, , 1993 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Tumor Necrosis Factor: Structure, Mechanism of Action, Role in Disease and Therapy : : 2nd International Conference on Tumor Necrosis Factor and Related Cytokines, Napa, Calif., January 1989 / / editors, B. Bonavida, G. Granger
| Tumor Necrosis Factor: Structure, Mechanism of Action, Role in Disease and Therapy : : 2nd International Conference on Tumor Necrosis Factor and Related Cytokines, Napa, Calif., January 1989 / / editors, B. Bonavida, G. Granger |
| Autore | Bonavida B |
| Pubbl/distr/stampa | Basel : , : S. Karger, , 1990 |
| Descrizione fisica | 1 online resource (X + 254 pages) : : 58 figures, 44 tables |
| Disciplina | 616.99/2 |
| Altri autori (Persone) |
BonavidaBenjamin
GrangerGale |
| Soggetto topico |
Oncology
Infectious Diseases Cardiovascular System Immunobiology Immunology Metabolic Diseases Metabolism Microbiology |
| ISBN | 3-318-05221-3 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Tumor Necrosis Factor |
| Record Nr. | UNINA-9910149634903321 |
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Bonavida B
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| Basel : , : S. Karger, , 1990 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Tumor Necrosis Factor: Structure-Function Relationship and Clinical Application : : 3rd International Conference on Tumor Necrosis Factor and Related Cytokines, Makuhari, Chiba, November 1990 / / editors, T. Osawa, B. Bonavida
| Tumor Necrosis Factor: Structure-Function Relationship and Clinical Application : : 3rd International Conference on Tumor Necrosis Factor and Related Cytokines, Makuhari, Chiba, November 1990 / / editors, T. Osawa, B. Bonavida |
| Autore | Osawa T |
| Pubbl/distr/stampa | Basel : , : S. Karger, , 1992 |
| Descrizione fisica | 1 online resource (X + 290 pages) : : 83 figures, 1 in color, 39 tables |
| Disciplina | 616.07/9 |
| Altri autori (Persone) |
OsawaT (Toshiaki)
BonavidaBenjamin |
| Soggetto topico |
Oncology
Immunology Biochemistry Infectious Diseases Microbiology Molecular Biology Pharmacology |
| ISBN | 3-318-05222-1 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Tumor Necrosis Factor |
| Record Nr. | UNINA-9910149635003321 |
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Osawa T
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| Basel : , : S. Karger, , 1992 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Tumor Surgery of the Head and Neck / / R.S. Pollack
| Tumor Surgery of the Head and Neck / / R.S. Pollack |
| Autore | Pollack R.S |
| Pubbl/distr/stampa | Basel : , : S. Karger, , 1975 |
| Descrizione fisica | 1 online resource (X + 206 pages) : : 90 figures |
| Disciplina | 617/.51 |
| Soggetto topico |
Oncology
Anesthesiology Immunology Orthopedics Surgery Otorhinolaryngology |
| ISBN | 3-318-05223-X |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910149634803321 |
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Pollack R.S
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| Basel : , : S. Karger, , 1975 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Tumor Therapy with Tumor Cells and Neuraminidase : : Cell Physiological, Immunological, and Oncological Aspects / / H.H. Sedlacek
| Tumor Therapy with Tumor Cells and Neuraminidase : : Cell Physiological, Immunological, and Oncological Aspects / / H.H. Sedlacek |
| Autore | Sedlacek H.H |
| Pubbl/distr/stampa | Basel : , : S. Karger, , 1987 |
| Descrizione fisica | 1 online resource (VIII + 96 pages) : : 19 tables |
| Soggetto topico |
Oncology
Biochemistry Immunology Internal Medicine Surgery |
| ISBN | 3-318-03410-X |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910156316603321 |
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Sedlacek H.H
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| Basel : , : S. Karger, , 1987 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Tumor-Induced Immune Suppression [[electronic resource] ] : Mechanisms and Therapeutic Reversal / / edited by Dmitry I. Gabrilovich, Arthur Andrew Hurwitz
| Tumor-Induced Immune Suppression [[electronic resource] ] : Mechanisms and Therapeutic Reversal / / edited by Dmitry I. Gabrilovich, Arthur Andrew Hurwitz |
| Edizione | [2nd ed. 2014.] |
| Pubbl/distr/stampa | New York, NY : , : Springer New York : , : Imprint : Springer, , 2014 |
| Descrizione fisica | 1 online resource (471 p.) |
| Disciplina |
571.6
571.8 599935 610 |
| Soggetto topico |
Cancer research
Immunology Medical microbiology Cell biology Human genetics Developmental biology Cancer Research Medical Microbiology Cell Biology Human Genetics Developmental Biology |
| ISBN | 1-4899-8056-3 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Preface.- Regulatory T Cells and Cancer -- Th17 cells in cancer -- Mast cells and immune response in cancer -- Myeloid-Derived Suppressor Cells in Tumor-Induced T-Cell Suppression and Tolerance -- Immunobiology of Dendritic Cells in Cancer -- Macrophages and Tumor Development -- Angiogenesis and Immune Suppression in Cancer -- Tim-3 Regulation of Cancer Immunity.- Transcriptional Regulation of Dendritic Cells in The Tumor Microenvironment -- S100A9, Inflammation, and Regulation of Immune Suppression in Cancer -- IDO in Inflammatory Programming and Immune Suppression in Cancer -- Defining the Fate and Function of Effector T cells through Galectin-1 – Galectin-1 Ligand Binding Interactions: Implications in Tumor Immunity -- Arginine Metabolism, a Major Pathway for the Suppressive Function of Myeloid-derived Suppressor Cells.- The Hypoxia-Adenosinergic Immunosuppression and Redirection of Immune Response in Tumor Microenvironment -- Molecular Pathways in Antigen Presenting Cells Involved in the Induction of Antigen-Specific T-Cell Tolerance -- Overcoming Immune Suppression: Therapeutic Strategies Targeting T-Cell Function in Cancer -- Index. |
| Record Nr. | UNINA-9910298349303321 |
| New York, NY : , : Springer New York : , : Imprint : Springer, , 2014 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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