Info
- Utilizzare la checkbox di selezione a fianco di ciascun documento per attivare le funzionalità di stampa, invio email, download nei formati disponibili del (i) record.
Antibody Fc : linking adaptive and innate immunity / / Margaret E. Ackerman, Falk Nimmerjahn
| Antibody Fc : linking adaptive and innate immunity / / Margaret E. Ackerman, Falk Nimmerjahn |
| Autore | Ackerman Margaret E |
| Pubbl/distr/stampa | London, : Academic Press, c2014 |
| Descrizione fisica | 1 online resource (xii, 363 pages) : illustrations (some color) |
| Disciplina | 616.07/93 |
| Collana | Gale eBooks |
| Soggetto topico |
Immunoglobulins
Antibody diversity |
| ISBN | 0-12-394818-5 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Front Cover; Antibody Fc: Linking Adaptive and Innate Immunity; Copyright Page; Contents; List of Contributors; 1. EFFECTOR MECHANISMS; 1 Antibody-Dependent Cellular Cytotoxicity (ADCC); Brief History of ADCC; Effector Cells; Receptors Involved; Mechanisms of ADCC; Recognition of the Target Cell and Cross-Linking of the Fc Receptor on the Effector Cell; Downstream Signals in the Effector Cell; Mechanisms of Killing; The Perforin/Granzyme Cell Death Pathway; The FAS-L Pathway; The ROS/ROI Pathway; ADCC Assays in Relation to Killing Mechanisms; ADCC in Monoclonal Antibody Therapy of Cancer
Versatility of Monoclonal Antibodies as Platforms for Cancer TherapyEvidence for ADCC in Cancer Therapy; ADCC in Infectious Disease: A Correlate of Protection?; Studies of Herpes Simplex Virus; Studies of Human and Simian Immunodeficiency Virus; Ongoing Debate and a Possible Consensus; Rational Modification of ADCC Activity; Enhancing the Link between ADCC and Adaptive Immunity; Perspectives: Future Directions; Acknowledgments; References; 2 Antibody-Dependent Cellular Phagocytosis and Its Impact on Pathogen Control; Introduction; Phagocytic Cells and Their Fcγ Receptors Various Receptors for IgGDifferential Expression of Fcγ Receptors on Phagocytic Cells; Fcγ Receptor-Mediated Phagocytosis by Phagocytes; Signaling by Activating FcγRs; Regulation of FcR Signals; Phagosome Maturation; Role of FcγR-Mediated Phagocytosis for Pathogen Uptake, Cellular Localization, and Pathogen Control; Bacteria; Avoiding Uptake into Phagocytes; Establishing an Intracellular Niche; Evasion Strategy of Bacteria: Proteolytic Degradation of Antibodies; Viruses; Targeting of Viruses to FcRs; Antibody-Dependent Enhancement of Infection; FcR-Mediated Uptake of Parasites and Fungi Leishmania-Specific Antibodies Can Shift the Balance between Th1 and Th2 ResponsesToxoplasma is Targeted to Lysosomes in the Presence of Specific Antibody; Antibody-Mediated Phagocytosis of Invasive Fungi; Concluding Remarks; References; 3 Interactions Between the Complement System and Fcγ Receptors; Preliminary Comments; Complement Fragment C3b Mediates Binding of IgG Immune Complexes to Primate Erythrocytes: Immune Adherence; Historical Perspective; Modern Times and Mechanisms: CR1 is Removed from Erythrocytes Complement Fragment C3d Mediates Binding of Substrates to CR2 on B Cells: Antigen Trafficking and Its Significance in HIV D...Similarities and Differences between CR1 and CR2; The Shuttle Mechanism: CR2 and Antigen Presentation; CR1, CR2, and AIDS; A Clue to a Mechanism: Lessons Learned from Dendritic Cells; Cooperation/Synergy between Fcγ Receptors and Complement Receptors on Effector Cells; In Vivo Studies of the Clearance of Opsonized Erythrocytes; In Vitro Evidence for Synergy between Fcγ Receptors and Complement Receptors; Interaction between FcγRIII and CR3; C3b-IgG as a Superopsonin Interaction between FcγR and Complement: Cancer Models |
| Record Nr. | UNINA-9910820381203321 |
Ackerman Margaret E
|
||
| London, : Academic Press, c2014 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Anticorpi e immunità : introduzione alla immunologia / Gus J.V. Nossal
| Anticorpi e immunità : introduzione alla immunologia / Gus J.V. Nossal |
| Autore | Nossal, Gustav J. V. |
| Pubbl/distr/stampa | Torino : Boringhieri, c1971 |
| Descrizione fisica | 259 p. : ill. ; 21 cm |
| Collana | Testi e manuali della scienza contemporanea. Serie di biologia e medicina |
| Soggetto topico |
Antigens
Immunoglobulins Immunology |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | ita |
| Record Nr. | UNISALENTO-991003422729707536 |
|
Nossal, Gustav J. V.
|
||
| Torino : Boringhieri, c1971 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. del Salento | ||
| ||
Approaches to the purifacation, analysis and characterization of antibody-based therapeutics / / edited by Allan Matte [and seven others]
| Approaches to the purifacation, analysis and characterization of antibody-based therapeutics / / edited by Allan Matte [and seven others] |
| Pubbl/distr/stampa | Amsterdam, Netherlands : , : Elsevier Limited, , [2020] |
| Descrizione fisica | 1 online resource (224 pages) |
| Disciplina | 615.36 |
| Soggetto topico |
Antibody-drug conjugates
Immunoglobulins |
| ISBN | 0-08-103019-3 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | 1. Overview of therapeutic antibodies; 2. Platform purification approaches; 3. Strategies in the context of mAb downstream process development; 4. Process-scale purification of antibody therapeutics; 5. Process analytics for mAb purification and process development; 6. Automation approaches for small-scale mAb purification and assay development; 7. Glycan characterization of therapeutics mAbs; 8. Characterization of therapeutic antibodies using mass spectrometry; 9. Antibody binding studies using surface plasmon resonance and bio-layer interferometry methods; 10. Higher-order structure characterization methods; 11. Conformational and colloidal stability analysis of mAbs; 12. Future trends and opportunities. |
| Record Nr. | UNINA-9910583324403321 |
| Amsterdam, Netherlands : , : Elsevier Limited, , [2020] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Genetica delle immunoglobuline / di A. Carbonara e M. De Marchi
| Genetica delle immunoglobuline / di A. Carbonara e M. De Marchi |
| Autore | Carbonara, Antonio |
| Pubbl/distr/stampa | Padova : Piccin, c1978 |
| Descrizione fisica | 64 p. : ill. ; 24 cm |
| Disciplina | 573 |
| Altri autori (Persone) | De Marchi, Mario |
| Collana | Quaderni di biologia. Serie rossa ; 27 |
| Soggetto topico |
Antibodies
Immunoglobulins |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | ita |
| Record Nr. | UNISALENTO-991003484039707536 |
|
Carbonara, Antonio
|
||
| Padova : Piccin, c1978 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. del Salento | ||
| ||
Guidance for industry in the manufacture and clinical evaluation of in vitro tests to detect nucleic acid sequences of human immunodeficiency viruses types 1 and 2 [[electronic resource]]
| Guidance for industry in the manufacture and clinical evaluation of in vitro tests to detect nucleic acid sequences of human immunodeficiency viruses types 1 and 2 [[electronic resource]] |
| Pubbl/distr/stampa | Rockville, MD : , : U.S. Dept. of Health and Human Services, Food and Drug Administration, Center for Biologics Evaluation and Research, , [1999] |
| Descrizione fisica | i, 22 pages : digital, PDF file |
| Soggetto topico |
HIV (Viruses)
Immunoglobulins Blood - Examination - Government policy - United States |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Manufacture and clinical evaluation of in vitro tests to detect nucleic acid sequences of human immunodeficiency viruses types 1 and 2 |
| Record Nr. | UNINA-9910698806203321 |
| Rockville, MD : , : U.S. Dept. of Health and Human Services, Food and Drug Administration, Center for Biologics Evaluation and Research, , [1999] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Idiotypes in biology and medicine
| Idiotypes in biology and medicine |
| Pubbl/distr/stampa | [Place of publication not identified], : Karger, 1990 |
| Descrizione fisica | 1 online resource (X + 214 pages) : : 38 figures, 18 tables |
| Soggetto topico |
Immunoglobulin Fragments
Epitopes Immunogenetic Phenomena Immunoglobulins Immune System Phenomena Antigens Peptide Fragments Phenomena and Processes Immunoproteins Serum Globulins Biological Factors Peptides Blood Proteins Chemicals and Drugs Globulins Amino Acids, Peptides, and Proteins Proteins Immunoglobulin Idiotypes |
| ISBN | 3-318-00040-X |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910155289503321 |
| [Place of publication not identified], : Karger, 1990 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Ig superfamily molecules in the nervous system / / edited by Peter Sonderegger
| Ig superfamily molecules in the nervous system / / edited by Peter Sonderegger |
| Pubbl/distr/stampa | Amsterdam : , : Harwood Academic Publishers, , 1998 |
| Descrizione fisica | 1 online resource (326 p.) |
| Disciplina | 616.0793 |
| Altri autori (Persone) | SondereggerPeter <1951-> |
| Collana | Cell adhesion and communication |
| Soggetto topico |
Immunoglobulins
Molecular neurobiology |
| Soggetto genere / forma | Electronic books. |
| ISBN |
0-429-17826-3
1-4822-8347-6 1-280-08019-1 9786610080199 0-203-30369-5 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Book Cover; Title; Contents; Preface to the Series; Foreword by Urs Rutishauser; Contributors; Structural Features of Neural Immunoglobulin Superfamily Adhesion Molecules; Molecular Interactions Involving Immunoglobulin Superfamily Adhesion Proteins; NCAM Polysialic Acid; Signal Transduction, Neurite Growth and Ig Superfamily Adhesion Molecules in the Vertebrate Nervous System; Ig Superfamily Kinases; Ig Superfamily Phosphatases; Molecular Mechanisms of Growth Cone Guidance in the Vertebrate Nervous System
Genetic Analysis of the Fasciclin II Cell Adhesion Molecule Reveals Multiple Roles During the Generation of Neuronal SpecificityNeural Cell Adhesion Molecules in Activity-dependent Plasticity; Ig Superfamily Molecules in Neural Regeneration in the CNS; Ig Superfamily Molecules in Myelination and Regeneration in the Peripheral Nervous System; Medical Genetics of Ig Superfamily Molecules; Index |
| Record Nr. | UNINA-9910451558503321 |
| Amsterdam : , : Harwood Academic Publishers, , 1998 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Ig superfamily molecules in the nervous system / / editor, Peter Sonderegger
| Ig superfamily molecules in the nervous system / / editor, Peter Sonderegger |
| Pubbl/distr/stampa | Amsterdam : , : Harwood Academic Publishers, , 1998 |
| Descrizione fisica | 1 online resource (326 pages) : illustrations |
| Disciplina | 616.0793 |
| Altri autori (Persone) | SondereggerPeter <1951-> |
| Collana | Cell adhesion and communication |
| Soggetto topico |
Immunoglobulins
Molecular neurobiology |
| ISBN |
0-429-17826-3
1-4822-8347-6 1-280-08019-1 9786610080199 0-203-30369-5 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Book Cover; Title; Contents; Preface to the Series; Foreword by Urs Rutishauser; Contributors; Structural Features of Neural Immunoglobulin Superfamily Adhesion Molecules; Molecular Interactions Involving Immunoglobulin Superfamily Adhesion Proteins; NCAM Polysialic Acid; Signal Transduction, Neurite Growth and Ig Superfamily Adhesion Molecules in the Vertebrate Nervous System; Ig Superfamily Kinases; Ig Superfamily Phosphatases; Molecular Mechanisms of Growth Cone Guidance in the Vertebrate Nervous System
Genetic Analysis of the Fasciclin II Cell Adhesion Molecule Reveals Multiple Roles During the Generation of Neuronal SpecificityNeural Cell Adhesion Molecules in Activity-dependent Plasticity; Ig Superfamily Molecules in Neural Regeneration in the CNS; Ig Superfamily Molecules in Myelination and Regeneration in the Peripheral Nervous System; Medical Genetics of Ig Superfamily Molecules; Index |
| Record Nr. | UNINA-9910784038103321 |
| Amsterdam : , : Harwood Academic Publishers, , 1998 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Ig superfamily molecules in the nervous system / / editor, Peter Sonderegger
| Ig superfamily molecules in the nervous system / / editor, Peter Sonderegger |
| Edizione | [1st ed.] |
| Pubbl/distr/stampa | Amsterdam : , : Harwood Academic Publishers, , 1998 |
| Descrizione fisica | 1 online resource (326 pages) : illustrations |
| Disciplina | 616.0793 |
| Altri autori (Persone) | SondereggerPeter <1951-> |
| Collana | Cell adhesion and communication |
| Soggetto topico |
Immunoglobulins
Molecular neurobiology |
| ISBN |
0-429-17826-3
1-4822-8347-6 1-280-08019-1 9786610080199 0-203-30369-5 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Book Cover; Title; Contents; Preface to the Series; Foreword by Urs Rutishauser; Contributors; Structural Features of Neural Immunoglobulin Superfamily Adhesion Molecules; Molecular Interactions Involving Immunoglobulin Superfamily Adhesion Proteins; NCAM Polysialic Acid; Signal Transduction, Neurite Growth and Ig Superfamily Adhesion Molecules in the Vertebrate Nervous System; Ig Superfamily Kinases; Ig Superfamily Phosphatases; Molecular Mechanisms of Growth Cone Guidance in the Vertebrate Nervous System
Genetic Analysis of the Fasciclin II Cell Adhesion Molecule Reveals Multiple Roles During the Generation of Neuronal SpecificityNeural Cell Adhesion Molecules in Activity-dependent Plasticity; Ig Superfamily Molecules in Neural Regeneration in the CNS; Ig Superfamily Molecules in Myelination and Regeneration in the Peripheral Nervous System; Medical Genetics of Ig Superfamily Molecules; Index |
| Record Nr. | UNINA-9910813465103321 |
| Amsterdam : , : Harwood Academic Publishers, , 1998 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
IgY-technology: production and application of egg yolk antibodies : basic knowledge for a successful practice / / Xiao-Ying Zhang [and three others], editors
| IgY-technology: production and application of egg yolk antibodies : basic knowledge for a successful practice / / Xiao-Ying Zhang [and three others], editors |
| Pubbl/distr/stampa | Cham, Switzerland : , : Springer, , [2021] |
| Descrizione fisica | 1 online resource (315 pages) |
| Disciplina | 616.0798 |
| Soggetto topico |
Immunoglobulins
Immunoglobulines Biotecnologia Avicultura |
| Soggetto genere / forma | Llibres electrònics |
| ISBN | 3-030-72688-6 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Intro -- Preface -- Acknowledgements -- Funding Acknowledgements -- Contents -- Contributors -- Part I: Biological Basis of IgY Technology -- 1: Development of IgY Technology: A Historical Perspective -- 1.1 Introduction -- 1.2 Development of IgY Technology -- 1.3 Application of IgY Products at a Glance -- 1.4 Application of the IgY Technology Driven by Legal Regulations in Favour of Animal Protection -- 1.5 Advantages and Limitations Driving IgY Technology -- References -- 2: The Domestic Hen -- 2.1 Introduction -- 2.2 Genetic Selection for Domestic Breeds of Chicken -- 2.3 Breeds of Chicken -- 2.4 Physiology of Chickens -- 2.4.1 Body Temperature -- 2.4.2 Anatomical Structures -- 2.4.3 Crop -- 2.4.4 Cloacal Chamber -- 2.4.5 Medullary Bone -- 2.5 Immune System of the Hen -- 2.5.1 Immune Tissues -- 2.5.1.1 Thymus and Bursa of Fabricius -- 2.5.1.2 Spleen -- 2.5.1.3 Defence System in the Reproductive Organs -- 2.5.1.4 Immune Response -- 2.6 Development of the Reproductive System and Egg Laying -- 2.6.1 Embryology of the Chicken -- 2.6.2 The Ovary -- 2.6.2.1 Follicular Development and Oocyte Maturation -- 2.6.3 Initiation of Laying -- 2.6.4 Reproductive System of the Hen -- 2.6.4.1 Egg Laying and the Oviduct -- 2.7 The Egg -- 2.7.1 Structure of Eggs -- 2.7.2 Composition of Egg Yolk -- 2.8 Concluding Remarks -- References -- 3: Immune Response in Mammals and Chickens -- 3.1 Evolutionary Context -- 3.2 Innate and Adaptive Immune Response -- 3.3 Innate Immune Response in Mammals and Chickens -- 3.3.1 Toll Like Receptors (TLRs) -- 3.3.2 Cytokine Production and Host Defence Peptides -- 3.4 Adaptive Immune Response -- 3.4.1 Lymphoid Tissues in Mammals and Chickens -- 3.4.2 B Cells, T Cells and MHC Class II Proteins -- 3.4.3 Antibody Secretion by B Cells -- 3.5 Genetic Basis for Diversity in Mammalian TCR and Immunoglobulins.
3.6 Genetic Basis for Diversity in Chicken TCR and Immunoglobulins -- 3.7 Structure of IgG and IgY -- References -- 4: Evolution of Immunoglobulins in Vertebrates -- 4.1 Introduction to Evolution -- 4.2 Immunoglobulin Classes in Vertebrates -- 4.3 Central Position of IgY in Antibody Evolution -- 4.4 Gene Organisation Related to Ig Evolution -- 4.5 Recombination-Activating Gene (RAG)-Mediated Rearrangement -- 4.6 Patterns of V(D)J Rearrangement -- References -- 5: Biology and Molecular Structure of Avian IgY Antibody -- 5.1 The Biology of IgY Production Compared to IgG -- 5.2 Molecular Structure of IgY -- 5.3 Generation of Immunoglobulin Diversity -- 5.4 Differential Expression of IgY Across Species -- 5.5 Generation of IgY(DeltaFc) -- References -- 6: IgY Cell Receptors and Immunity Transfer -- 6.1 Constant Region of Immunoglobulins (Ig) -- 6.2 Transfer of Maternal Immunoglobulins -- 6.3 Transfer of IgY -- 6.3.1 Transfer from the Maternal Circulation to the Yolk of the Oocytes -- 6.3.2 Transfer from the Embryonic Yolk Sac to the Embryonic Blood Stream -- 6.4 IgY Receptor Family -- 6.5 Prospective -- References -- 7: Biorhythms of Hens -- 7.1 Introduction -- 7.2 Observed Rhythms in Hens -- 7.3 Impact of Ageing -- References -- Part II: Core Methods of IgY Technology -- 8: Keeping Laying Hens to Obtain Antibodies -- 8.1 General Introduction -- 8.2 Legislation -- 8.3 Climate, Air Quality, Light and Noise -- 8.4 Enrichment and Nourishment -- 8.4.1 Nest Box -- 8.4.2 Perches -- 8.4.3 Flooring -- 8.4.4 Food and Water -- 8.5 Factors Impacting on IgY Production -- 8.6 Example of a Conventional Housing System -- 8.7 Specific Pathogen Free (SPF) Hens -- 8.8 Specific Pathogen Free (SPF) Avian Facility -- References -- 9: Other Avian Species: Ostrich, Quail, Turkey, Duck and Goose -- 9.1 Introduction -- 9.2 Ostrich Struthio camelus. 9.3 Japanese Quail Coturnix japonica -- 9.4 Turkey Meleagris gallopavo -- 9.5 Duck Anas platyrhynchos -- 9.6 Goose Anser anser -- 9.7 Summary -- References -- 10: Immunization of Hens -- 10.1 Maintenance of Hens -- 10.2 Source of Antigens -- 10.2.1 Whole Virus or Bacteria -- 10.2.2 Recombinant Proteins -- 10.2.3 Haptens -- 10.2.4 Virus-Like Particles -- 10.2.5 Bacterial Ghosts -- 10.2.6 Virosomes -- 10.2.7 Nucleic Acid Vaccines as Immunogens -- 10.2.8 Vaccine Products as Antigens -- 10.3 Routes of Administration -- 10.4 Amount of Antigen -- 10.5 Adjuvant -- 10.6 Immunization Intervals -- 10.7 Monitoring the IgY Titre -- 10.8 Immunization for the Generation of IgY-scFv -- 10.9 Discussion -- References -- 11: Extraction and Purification of IgY -- 11.1 Introduction -- 11.1.1 Properties of IgY -- 11.1.2 General Considerations for the Extraction of IgY -- 11.2 Egg Collection and Separation of Yolk from Egg White -- 11.3 Delipidation of Egg Yolk -- 11.3.1 Water Dilution -- 11.3.2 Polyethylene Glycol Precipitation -- 11.3.3 Anionic Polysaccharides -- 11.3.4 Organic Solvents -- 11.3.5 Specific Chemicals -- 11.4 Extraction of IgY Following Delipidation -- 11.4.1 Salt Precipitation -- 11.4.2 PEG Precipitation -- 11.4.3 Filtration -- 11.4.4 Aqueous Biphasic Systems (ABS) -- 11.5 Purification of IgY -- 11.5.1 Cation Exchange Chromatography -- 11.5.2 Hydrophobic Charge-Induction Chromatography -- 11.5.3 Affinity Chromatography -- 11.6 Comparison of Methods Used for Delipidation and Extraction of IgY -- 11.7 Commercially Available IgY Extraction Kits -- 11.8 Methods Used to Confirm Purity and Activity of IgY -- 11.8.1 Molecular Weight and Structure -- 11.8.2 Biological Activity of IgY -- 11.9 Purification and Characterization of Monoclonal IgY -- 11.10 The Storage and Stability of IgY Product -- References -- 12: IgY Delivery and Dosage Form -- 12.1 Introduction. 12.2 Oral Administrations -- 12.3 Parenteral Administrations -- 12.4 IgY in Food and Feed Use -- 12.5 Perspective -- References -- 13: Monoclonal IgY Antibodies -- 13.1 Introduction -- 13.1.1 Monoclonal Antibody and Functional Antibody Fragments -- 13.2 Genetically Engineered Chicken Antibodies -- 13.2.1 Recombinant IgY Fragments -- 13.2.2 Chimeric Antibodies -- 13.2.3 Humanized Antibody -- 13.3 Biomolecular Methods for Monoclonal IgY Generation -- 13.3.1 Hybridoma Technology -- 13.3.2 DT40 Cell Line -- 13.3.3 Antibody Display Technologies -- 13.3.3.1 Phage Display -- 13.3.3.2 Yeast Surface Display -- 13.3.3.3 Ribosomal Display -- 13.3.4 Gel Encapsulated Microenvironment (GEM) Screening Technology -- 13.4 Amino-Acid Synthetic for Monoclonal IgY Generation Antibody Mimetics -- 13.5 Conclusion and Future Prospect -- References -- 14: Protein Production in Transgenic Chickens -- 14.1 Introduction -- 14.2 Protein Production Methods -- 14.3 Advantages of Protein Production in Chicken Egg White -- 14.4 Overview of Chicken Transgenesis -- 14.4.1 Evolution of Delivery Methods and Germline Transmission Frequencies -- 14.4.2 The Effects of Promoters in Protein Expression -- 14.5 Closing Remarks -- References -- Part III: Applications of IgY Technology -- 15: Applications of IgY in Veterinary Medicine -- 15.1 Introduction -- 15.2 Cattle -- 15.2.1 Diarrhoea in Calves -- 15.2.2 Bovine Viral Diarrhoea Virus (BVDV): Prevention and Treatment -- 15.2.3 Mastitis -- 15.3 Pigs -- 15.3.1 Diarrhoea in Pigs -- 15.4 Poultry -- 15.4.1 IgY Treatment of Bacterial Infections of Poultry -- 15.4.2 IgY Treatment of Viral Infections of Poultry -- 15.4.3 IgY Treatment of Protozoan Infections of Poultry -- 15.5 Applications of IgY in Aquaculture -- 15.6 Dogs -- 15.6.1 Canine Parvovirus -- 15.6.2 Canine Morbillivirus -- 15.7 Applications of IgY to Treat Other Animals. 15.8 Application of IgY Antibodies in Detection and Immunoassay -- 15.8.1 Igy Based Diagnostics of Animal Diseases -- 15.8.2 IgY for Detection of Microbial Contamination in Sea Food -- 15.9 Conclusion and Perspectives -- References -- 16: Applications of IgY in Human Medicine -- 16.1 Introduction -- 16.2 Human Respiratory Infections -- 16.2.1 Severe Acute Respiratory Syndrome Coronaviruses (SARS-CoV) -- 16.2.2 Influenza -- 16.2.3 Hantavirus Pulmonary Syndrome -- 16.2.4 Pseudomonas aeruginosa -- 16.3 Other Human Viral Infections -- 16.3.1 Rabies Virus -- 16.3.2 Emerging Viral Threats -- 16.4 Helicobacter pylori and Gastric Pathogenesis -- 16.5 Mutans Streptococci and Dental Caries -- 16.5.1 Introduction -- 16.5.2 Vaccination Against Dental Caries -- 16.5.3 Passive Immunization -- 16.6 Antitoxin IgY Therapies and Approaches -- 16.6.1 Introduction -- 16.6.2 Escherichia coli -- 16.6.3 Clostridium tetani -- 16.6.4 Clostridium botulinum -- 16.6.5 Clostridium difficile -- 16.6.6 Clostridium perfringens -- 16.6.7 Staphylococcus aureus -- 16.7 Antivenoms -- 16.7.1 Snake Venom -- 16.7.2 Clinical Manifestations of Envenoming -- 16.7.3 IgY Antivenoms: the Key Therapy for Snakebite Envenoming -- 16.7.4 Pharmacological Characterization and Neutralization of Venoms -- References -- 17: IgY Industries and Markets -- 17.1 Introduction -- 17.2 Case-studies of IgY Companies -- 17.2.1 Gentian AS (Moss, Norway) -- 17.2.2 Immunsystem AB (Uppsala, Sweden) -- 17.2.3 Bioinnovo (Castelar, Argentina) -- 17.2.4 Crystal Biosciences (California, USA) -- 17.2.5 Ovagen Group Ltd. -- 17.2.6 ADBioTech (South Korea) -- 17.3 Brief Profiles of Other IgY Companies -- 17.3.1 EW Nutrition (Visbek, Germany) -- 17.3.2 Avianax (North Dakota, USA) -- 17.3.3 IGY Life Sciences (Ontario, Canada) -- 17.3.4 Ostrich Pharma Corp (Kyoto, Japan) -- 17.4 Intellectual Property of IgY. 17.4.1 IgY: Patenting a Product Already Existing in Nature. |
| Record Nr. | UNINA-9910488722103321 |
| Cham, Switzerland : , : Springer, , [2021] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
