GM3 Signaling [[electronic resource] /] / by Cheorl-Ho Kim |
Autore | Kim Cheorl-Ho |
Edizione | [1st ed. 2020.] |
Pubbl/distr/stampa | Singapore : , : Springer Singapore : , : Imprint : Springer, , 2020 |
Descrizione fisica | 1 online resource (VII, 138 p. 32 illus., 26 illus. in color.) |
Disciplina | 378.1662 |
Soggetto topico |
Gene expression
Cancer research Genetics Biochemistry Cell membranes Gene Expression Cancer Research Genetics and Genomics Biochemistry, general Membrane Biology Expressió gènica Càncer Bioquímica Membranes (Biologia) |
Soggetto genere / forma | Llibres electrònics |
ISBN | 981-15-5652-0 |
Formato | Materiale a stampa ![]() |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto | 1. History of sialic acids, gangliosides and GM3 -- 2. Synthesis of GM3 -- 3. Molecular localization of GM3 in cells -- 4. Basic function of GM3 as an interacting molecule -- 5. GD3 mimetics with a neurite forming capacity -- 6. GM3 as a pathogenic infection receptor -- 7. GM3 and related gangliosides prevent inflammation and atherosclerosis -- 8. GM3 has an anti-tumor capacity -- 9. GM3 suppresses tumor angiogenesis -- 10. Interaction between EGFR and GM3 -- 11. Membrane ganglioside-specific neuraminidase 3 (NEU3) regulates GM3 signaling -- 12. Regulation of GM3-mediated EGFR signaling by NEU3 sialidase -- 13. VEGFR-GM3 interaction in angiogenesis -- 14. GM3, competing with GM1, interaction with urokinase plasminogen activator receptor (uPAR) in endothelial caveolar-lipid rafts inhibits angiogenesis -- 15. GM3 interacts with TGFβ Rs in the epithelial-mesenchymal transition (EMT) during posterior capsular opacification (PCO) formation -- 16. Galectin-1 promotes tumor growth and escapes immune surveillance -- 17. GM3-HGFR, FGFR and PDGFR cancer cell behavior, and IGF-1R in diabetic wound healing -- 18. GM3, caveolin-1 and insulin receptor in insulin resistance -- 19. GM3 suppresses arthritis -- 20. GM3 protects cochlear hair cells and hearing from corti degeneration -- 21. GM3 increases osteoclast differentiation via direct GM3 cooperation with RANKL and IGF-1 -- 22. GM3 in leukemic cells into terminal differentiation -- 23. α2,3-Sialyllactose (3SL) or α2,6-sialyllactose (6SL) of GM3 glycan in innate immunity. . |
Record Nr. | UNINA-9910416108503321 |
Kim Cheorl-Ho
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Singapore : , : Springer Singapore : , : Imprint : Springer, , 2020 | ||
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Lo trovi qui: Univ. Federico II | ||
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Handbook of Oxidative Stress in Cancer: Mechanistic Aspects [[electronic resource] /] / edited by Sajal Chakraborti, Bimal K Ray, Sushanta Roychowdhury |
Pubbl/distr/stampa | Singapore : , : Springer Singapore : , : Imprint : Springer, , 2020 |
Descrizione fisica | 1 online resource (X, 1690 p. 20 illus., 10 illus. in color.) |
Disciplina | 614.5999 |
Soggetto topico |
Cancer research
Genetics Cancer Research Genetics and Genomics Estrès oxidatiu Càncer Oxigen actiu |
Soggetto genere / forma | Llibres electrònics |
ISBN | 981-15-4501-4 |
Formato | Materiale a stampa ![]() |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Record Nr. | UNINA-9910444254903321 |
Singapore : , : Springer Singapore : , : Imprint : Springer, , 2020 | ||
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Lo trovi qui: Univ. Federico II | ||
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Hidden Treasures in Contemporary RNA Sequencing / / by Serghei Mangul, Harry Taegyun Yang, Eleazar Eskin, Noah Zaitlen |
Autore | Mangul Serghei |
Edizione | [1st ed. 2019.] |
Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2019 |
Descrizione fisica | 1 online resource (99 pages) |
Disciplina |
547.79
572.8633 |
Collana | SpringerBriefs in Computer Science |
Soggetto topico |
Bioinformatics
Genetics Computational Biology/Bioinformatics Genetics and Genomics |
ISBN | 3-030-13973-5 |
Formato | Materiale a stampa ![]() |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto | Abstract -- Main Text -- Acknowledgement -- Disclosure -- References. |
Record Nr. | UNINA-9910337570903321 |
Mangul Serghei
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Cham : , : Springer International Publishing : , : Imprint : Springer, , 2019 | ||
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Lo trovi qui: Univ. Federico II | ||
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Histone Deacetylase Inhibitors — Epidrugs for Neurological Disorders [[electronic resource] /] / by Shabir Ahmad Ganai |
Autore | Ganai Shabir Ahmad |
Edizione | [1st ed. 2019.] |
Pubbl/distr/stampa | Singapore : , : Springer Singapore : , : Imprint : Springer, , 2019 |
Descrizione fisica | 1 online resource (XVII, 93 p. 8 illus., 5 illus. in color.) |
Disciplina | 612.8 |
Soggetto topico |
Neurosciences
Pharmacology Genetics Proteins Posttranslational modification Pharmacology/Toxicology Genetics and Genomics Protein Science Posttranslational Modification |
ISBN | 981-13-8019-8 |
Formato | Materiale a stampa ![]() |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto | Chapter 1. Role of Epigenetics in neurological diseases -- Chapter 2. Epigenetic enzymes and the drawbacks of conventional therapeutic regimens -- Chapter 3. Distinct classes of HDACs -- Chapter 4. HDAC implications in neurological diseases -- Chapter 5. HDAC inhibitors and their structurally distinct groups -- Chapter 6. HDAC inhibitors as novel therapeutic option against therapeutically challenging neurological disorders -- Chapter 7. Current Challenges with HDAC inhibitor based therapeutic intervention against neurological maladies -- Chapter 8. Escalating need of isoform selective inhibitors for enhanced therapeutic efficacy -- Chapter 9. Combinatorial therapeutic regimens using HDAC inhibitors in conjunction with conventional therapeutic agents -- Chapter 10. Future directions of epigenetic research in tackling neurological complications. |
Record Nr. | UNINA-9910350356103321 |
Ganai Shabir Ahmad
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Singapore : , : Springer Singapore : , : Imprint : Springer, , 2019 | ||
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Lo trovi qui: Univ. Federico II | ||
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Horizontal Gene Transfer : Breaking Borders Between Living Kingdoms / / edited by Tomás G. Villa, Miguel Viñas |
Edizione | [1st ed. 2019.] |
Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2019 |
Descrizione fisica | 1 online resource (422 pages) |
Disciplina |
574.873282
572.877 |
Soggetto topico |
Genetics
Drug resistance Evolutionary biology Microbial ecology Medical genetics Genetic engineering Genetics and Genomics Drug Resistance Evolutionary Biology Microbial Ecology Gene Function Genetic Engineering |
ISBN | 3-030-21862-7 |
Formato | Materiale a stampa ![]() |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto | Part 1: Horizontal gene transfer among bacteria and bacteriophages -- Chapter 1: Horizontal gene transfer in bacteria, an overview of the mechanisms involved -- Chapter 2: Alternative ways to exchange DNA: unconventional conjugation among bacteria -- Chapter 3: Horizontal gene transfer between bacteriophages and bacteria: Antibiotic resistances and toxin production -- Chapter 4: Genomic islands and the evolution of multidrug-resistant bacteria Mario Juhas -- Chapter 5: Horizontal gene transfer and genome evolution in the phylum Actinobacteria -- Chapter 6: Photobacterium damselae: How horizontal gene transfer shaped two different pathogenic lifestyles in a marine bacterium -- Part 2: Horizontal gene transfer between bacteria and animals, plants, amoeba and fungi -- chapter 7: Horizontal gene transfer in Metazoa: Examples and Methods -- Chapter 8: Horizontal gene transfer between Wolbachia and animals -- Chapter 9: Horizontal gene transfer in obligate parasites -- Chapter 10: Association between Horizontal gene transfer and Adaptation of gastric human pathogen Helicobacter pylori to host -- Chapter 11: The Rhizobiaceae bacteria transferring genes to higher plants Martha -- Chapter 12: Role of horizontal gene transfer in evolution of plant genome -- Chapter 13: Fungal horizontal gene transfer: a history beyond the Phylogenetic Kingdoms -- Chapter 14: Transfer of secondary metabolite gene clusters: assembly and reorganization ofthe b-lactam gene cluster from bacteria to fungi and arthropods -- Chapter 15: Horizontal gene transfer Among Neisseria species and humans -- Chapter 16: Implications of Lateral or Horizontal Gene Transfer from Bacteria to the Human Gastro-Intestinal System for Cancer Development and Treatment -- Chapter 17: Role of Horizontal Gene Transfer in Cancer Progression. . |
Record Nr. | UNINA-9910349447603321 |
Cham : , : Springer International Publishing : , : Imprint : Springer, , 2019 | ||
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Lo trovi qui: Univ. Federico II | ||
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Labster Virtual Lab Experiments: Basic Biochemistry [[electronic resource] /] / by Aaron Gardner, Wilko Duprez, Sarah Stauffer, Dewi Ayu Kencana Ungu, Frederik Clauson-Kaas |
Autore | Gardner Aaron |
Edizione | [1st ed. 2019.] |
Pubbl/distr/stampa | Berlin, Heidelberg : , : Springer Berlin Heidelberg : , : Imprint : Springer Spektrum, , 2019 |
Descrizione fisica | 1 online resource (IX, 87 p. 47 illus.) |
Disciplina | 574.192 |
Soggetto topico |
Biochemistry
Biology—Technique Medical biochemistry Cell biology Genetics Biochemistry, general Biological Techniques Medical Biochemistry Cell Biology Genetics and Genomics |
ISBN | 3-662-58499-9 |
Formato | Materiale a stampa ![]() |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto | Ionic and Covalent Bonds -- Introduction to Biological Macromolecules -- Carbohydrates -- Enzyme Kinetics. |
Record Nr. | UNINA-9910337957103321 |
Gardner Aaron
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Berlin, Heidelberg : , : Springer Berlin Heidelberg : , : Imprint : Springer Spektrum, , 2019 | ||
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Lo trovi qui: Univ. Federico II | ||
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Labster Virtual Lab Experiments: Basic Genetics [[electronic resource] /] / by Sarah Stauffer, Aaron Gardner, Wilko Duprez, Dewi Ayu Kencana Ungu, Philip Wismer |
Autore | Stauffer Sarah |
Edizione | [1st ed. 2018.] |
Pubbl/distr/stampa | Berlin, Heidelberg : , : Springer Berlin Heidelberg : , : Imprint : Springer Spektrum, , 2018 |
Descrizione fisica | 1 online resource (IX, 64 p. 40 illus. in color. Textbook for German language market.) |
Disciplina | 576.5 |
Soggetto topico |
Genetics
Human genetics Molecular biology Learning Instruction Genetics and Genomics Human Genetics Molecular Medicine Learning & Instruction |
ISBN | 3-662-57999-5 |
Formato | Materiale a stampa ![]() |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto | Mendelian Inheritance Simulation -- Polymerase Chain Reaction -- Animal Genetics -- Gene Expression -- Gene Regulation. |
Record Nr. | UNINA-9910484453803321 |
Stauffer Sarah
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Berlin, Heidelberg : , : Springer Berlin Heidelberg : , : Imprint : Springer Spektrum, , 2018 | ||
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Lo trovi qui: Univ. Federico II | ||
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Labster Virtual Lab Experiments: Genetics of Human Diseases [[electronic resource] /] / by Aaron Gardner, Sarah Stauffer, Lindsay Petley-Ragan, Philip Wismer, Dewi Ayu Kencana Ungu |
Autore | Gardner Aaron |
Edizione | [1st ed. 2019.] |
Pubbl/distr/stampa | Berlin, Heidelberg : , : Springer Berlin Heidelberg : , : Imprint : Springer Spektrum, , 2019 |
Descrizione fisica | 1 online resource (IX, 76 p. 43 illus. in color.) |
Disciplina | 575.1078 |
Soggetto topico |
Genetics
Human genetics Virology Learning Instruction Molecular biology Genetics and Genomics Human Genetics Learning & Instruction Molecular Medicine |
ISBN | 3-662-58744-0 |
Formato | Materiale a stampa ![]() |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto | Monogenic Disorders -- Cytogenetics -- Medical Genetics -- Viral Gene Therapy. |
Record Nr. | UNINA-9910337957003321 |
Gardner Aaron
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Berlin, Heidelberg : , : Springer Berlin Heidelberg : , : Imprint : Springer Spektrum, , 2019 | ||
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Lo trovi qui: Univ. Federico II | ||
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Life Extension : Lessons from Drosophila / / edited by Alexander M. Vaiserman, Alexey A. Moskalev, Elena G. Pasyukova |
Edizione | [1st ed. 2015.] |
Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2015 |
Descrizione fisica | 1 online resource (350 p.) |
Disciplina |
591.35
610 612.67 618.97 |
Collana | Healthy Ageing and Longevity |
Soggetto topico |
Medicine - Research
Biology - Research Genetics Geriatrics Biomedical Research Genetics and Genomics |
ISBN | 3-319-18326-5 |
Formato | Materiale a stampa ![]() |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto | Preface -- SECTION I: Genetic regulation of longevity -- Mutations and quantitative genetic variation: lessons from Drosophila -- Modulation of Drosophila lifespan by neuronal genes -- Life span, stress resistance and age-dependent transcriptome dynamics in fruit flies with constitutive and conditional overexpression of GADD45 -- Superoxide dismutase over-expression and the mitochondrial unfolded protein response -- Effect of Wolbachia infection on aging and longevity-associated genes in Drosophila -- SECTION II: Drosophila models for aging-associated diseases -- Skeletal muscle homeostasis and aging -- Drosophila models of cardiac disease -- Genetic modulation of cardiac functional aging -- Functional links between circadian clocks, redox state and aging in Drosophila -- Drosophila models in therapeutic drug discovery -- SECTION III: Life-extending treatments -- Phytochemicals with lifespan extension effect in Drosophila -- Life extension in Drosophila by inhibitors of histone deacetylases -- Drosophila healthspan extension using dietary manipulation -- The effect of the artificial atmosphere on the flies’ longevity -- Effects of several mild stresses applied in adults on aging and longevity -- Life extension via stage-specific drug interventions in Drosophila -- Index. |
Record Nr. | UNINA-9910298262603321 |
Cham : , : Springer International Publishing : , : Imprint : Springer, , 2015 | ||
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Lo trovi qui: Univ. Federico II | ||
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Marine Metagenomics [[electronic resource] ] : Technological Aspects and Applications / / edited by Takashi Gojobori, Tokio Wada, Takanori Kobayashi, Katsuhiko Mineta |
Edizione | [1st ed. 2019.] |
Pubbl/distr/stampa | Singapore : , : Springer Singapore : , : Imprint : Springer, , 2019 |
Descrizione fisica | 1 online resource (271 pages) |
Disciplina | 572.8293 |
Soggetto topico |
Bioinformatics
Marine sciences Freshwater Genetics Bioinformatics Computational biology Aquatic ecology Virology Marine & Freshwater Sciences Genetics and Genomics Computer Appl. in Life Sciences Freshwater & Marine Ecology |
ISBN | 981-13-8134-8 |
Formato | Materiale a stampa ![]() |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto | Part 1: Technological Aspects of Marine Metagenomics: Sample Collection and preparation methods -- Chapter 1: Metagenomic methods: from seawater to the database -- Chapter 2: Collection of microbial DNA from marine sediments -- Chapter 3: Primer design, evaluation of primer universality and estimation of identification power of amplicon sequences in silico -- Chapter 4: High coverage expression profiling (HiCEP) of microbial community genomes in the ocean -- Part 2: Technological Aspects of Marine Metagenomics: Metagenome Data Analysis -- Chapter 5: Introduction and application of Digital DNA Chip Analysis (DDCA) to metagenomic analysis -- Chapter 6: Horizontal gene transfer in marine environment: a technical perspective on metagenomics -- Chapter 7: MAPLE enables functional assessment of microbiota in various environments -- Part 3: Applications in Ocean and Fisheries Sciences: Diversity and Function of Microbial Community -- Chapter 8: Comparison of microscopic and PCR amplicon and shotgun metagenomic approaches applied to marine diatom communities -- Chapter 9: Seasonal dynamics of bacterial community composition in coastal seawater at Sendai Bay, Japan -- Chapter 10: Shotgun metagenome analyses: seasonality monitoring in Sendai Bay and search for red tide marker sequences -- Chapter 11: Distribution and community composition of ammonia-oxidizing archaea and bacteria in coastal sediments in response to sediment material gradients at Sendai Bay, Japan -- Chapter 12: Marine metagenomic sequence counts of reads assigned to taxa consistently proportionate to read counts obtained for per g of sea water sample -- Chapter 13: New aquaculture technology based on host-symbiotic co-metabolism -- Part 4: Applications in Ocean and Fisheries Sciences: Analysis of the Red Tide -- Chapter 14: Influences of diurnal sampling bias on fixed-point monitoring of plankton biodiversity determined using a massively parallel sequencing-based technique -- Chapter 15: Detection of microorganisms which show positive or negative correlations with red tide causing alga using a new time-series network model. |
Record Nr. | UNINA-9910350352003321 |
Singapore : , : Springer Singapore : , : Imprint : Springer, , 2019 | ||
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Lo trovi qui: Univ. Federico II | ||
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