From genes to genomes [[electronic resource] ] : concepts and applications of DNA technology |
Autore | Dale Jeremy (Jeremy W.) |
Edizione | [2nd ed.] |
Pubbl/distr/stampa | Hoboken, : Wiley, 2008 |
Descrizione fisica | 1 online resource (396 p.) |
Disciplina |
572.8
572.86 660.65 |
Altri autori (Persone) | von SchantzMalcolm |
Soggetto topico |
Cloning, Molecular
DNA, Recombinant DNA Genes Genetic Engineering Genomes Genetic engineering Genome Genetic Structures Genetic Techniques Investigative Techniques Genetic Phenomena Nucleic Acids Analytical, Diagnostic and Therapeutic Techniques and Equipment Phenomena and Processes Nucleic Acids, Nucleotides, and Nucleosides Chemicals and Drugs Genetics Biology Health & Biological Sciences |
Soggetto genere / forma | Electronic books. |
ISBN |
0-470-85690-4
1-282-34827-2 0-470-51870-7 0-470-01734-1 9786612348273 1-280-62202-4 9786610622023 0-470-85691-2 |
Formato | Materiale a stampa ![]() |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto |
""From Genes to Genomes""; ""Contents""; ""Preface""; ""1: Introduction""; ""2: Basic Molecular Biology""; ""2.1 Nucleic acid structure""; ""2.2 What is a gene?""; ""2.3 Information flow: gene expression""; ""2.4 Gene structure and organization""; ""3: How to Clone a Gene""; ""3.1 What is cloning?""; ""3.2 Overview of the procedures""; ""3.3 Gene libraries""; ""3.4 Hybridization""; ""3.5 Polymerase chain reaction""; ""3.6 Extraction and purification of nucleic acids""; ""3.7 Detection and quantitation of nucleic acids""; ""3.8 Gel electrophoresis""; ""4: Cutting and Joining DNA""
""4.1 Restriction endonucleases""""4.2 Ligation""; ""4.3 Modification of restriction fragment ends""; ""4.4 Other ways of joining DNA molecules""; ""5: Vectors""; ""5.1 Plasmid vectors""; ""5.2 Vectors based on the lambda bacteriophage""; ""5.3 Cosmids""; ""5.4 M13 vectors""; ""5.5 Expression vectors""; ""5.6 Vectors for cloning and expression in eukaryotic cells""; ""5.7 Supervectors: YACs and BACs""; ""5.8 Summary""; ""6: Genomic and cDNA Libraries""; ""6.1 Genomic libraries""; ""6.2 Growing and storing libraries""; ""6.3 cDNA libraries""; ""6.4 Random, arrayed and ordered libraries"" ""7: Finding the Right Clone""""7.1 Screening libraries with gene probes""; ""7.2 Screening expression libraries with antibodies""; ""7.3 Subcloning""; ""7.4 Characterization of plasmid clones""; ""8: Polymerase Chain Reaction""; ""8.1 The PCR reaction""; ""8.2 PCR in practice""; ""8.3 Cloning PCR products""; ""8.4 Long-range PCR""; ""8.5 Reverse-transcription PCR""; ""8.6 Rapid amplification of cDNA ends""; ""8.7 Quantitative PCR""; ""8.8 Applications of PCR""; ""9: Characterization of a Cloned Gene""; ""9.1 DNA sequencing""; ""9.2 Databank entries and annotation""; ""9.3 Sequence analysis"" ""9.4 Sequence comparisons""""9.5 Protein structure""; ""9.6 Confirming gene function""; ""10: Analysis of Gene Expression""; ""10.1 Analysing transcription""; ""10.2 Methods for studying the promoter""; ""10.3 Regulatory elements and DNA-binding proteins""; ""10.4 Translational analysis""; ""11: Products from Native and Manipulated Cloned Genes""; ""11.1 Factors affecting expression of cloned genes""; ""11.2 Expression of cloned genes in bacteria""; ""11.3 Expression in eukaryotic host cells""; ""11.4 Adding tags and signals""; ""11.5 In vitro mutagenesis""; ""11.6 Vaccines"" ""12: Genomic Analysis""""12.1 Genome sequencing""; ""12.2 Analysis and annotation""; ""12.3 Comparing genomes""; ""12.4 Genome browsers""; ""12.5 Relating genes and functions: genetic and physical maps""; ""12.6 Transposon mutagenesis and other screening techniques""; ""12.7 Conclusion""; ""13: Analysis of Genetic Variation""; ""13.1 Single nucleotide polymorphisms""; ""13.2 Larger-scale variations""; ""13.3 Other methods for studying variation""; ""13.4 Human genetic diseases""; ""13.5 Molecular phylogeny""; ""14: Post-genomic Analysis""; ""14.1 Analysing transcription; transcriptomes"" ""14.2 Array-based methods"" |
Record Nr. | UNINA-9910143510103321 |
Dale Jeremy (Jeremy W.)
![]() |
||
Hoboken, : Wiley, 2008 | ||
![]() | ||
Lo trovi qui: Univ. Federico II | ||
|
From genes to genomes [[electronic resource] ] : concepts and applications of DNA technology |
Autore | Dale Jeremy (Jeremy W.) |
Edizione | [2nd ed.] |
Pubbl/distr/stampa | Hoboken, : Wiley, 2008 |
Descrizione fisica | 1 online resource (396 p.) |
Disciplina |
572.8
572.86 660.65 |
Altri autori (Persone) | von SchantzMalcolm |
Soggetto topico |
Cloning, Molecular
DNA, Recombinant DNA Genes Genetic Engineering Genomes Genetic engineering Genome Genetic Structures Genetic Techniques Investigative Techniques Genetic Phenomena Nucleic Acids Analytical, Diagnostic and Therapeutic Techniques and Equipment Phenomena and Processes Nucleic Acids, Nucleotides, and Nucleosides Chemicals and Drugs Genetics Biology Health & Biological Sciences |
ISBN |
0-470-85690-4
1-282-34827-2 0-470-51870-7 0-470-01734-1 9786612348273 1-280-62202-4 9786610622023 0-470-85691-2 |
Formato | Materiale a stampa ![]() |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto |
""From Genes to Genomes""; ""Contents""; ""Preface""; ""1: Introduction""; ""2: Basic Molecular Biology""; ""2.1 Nucleic acid structure""; ""2.2 What is a gene?""; ""2.3 Information flow: gene expression""; ""2.4 Gene structure and organization""; ""3: How to Clone a Gene""; ""3.1 What is cloning?""; ""3.2 Overview of the procedures""; ""3.3 Gene libraries""; ""3.4 Hybridization""; ""3.5 Polymerase chain reaction""; ""3.6 Extraction and purification of nucleic acids""; ""3.7 Detection and quantitation of nucleic acids""; ""3.8 Gel electrophoresis""; ""4: Cutting and Joining DNA""
""4.1 Restriction endonucleases""""4.2 Ligation""; ""4.3 Modification of restriction fragment ends""; ""4.4 Other ways of joining DNA molecules""; ""5: Vectors""; ""5.1 Plasmid vectors""; ""5.2 Vectors based on the lambda bacteriophage""; ""5.3 Cosmids""; ""5.4 M13 vectors""; ""5.5 Expression vectors""; ""5.6 Vectors for cloning and expression in eukaryotic cells""; ""5.7 Supervectors: YACs and BACs""; ""5.8 Summary""; ""6: Genomic and cDNA Libraries""; ""6.1 Genomic libraries""; ""6.2 Growing and storing libraries""; ""6.3 cDNA libraries""; ""6.4 Random, arrayed and ordered libraries"" ""7: Finding the Right Clone""""7.1 Screening libraries with gene probes""; ""7.2 Screening expression libraries with antibodies""; ""7.3 Subcloning""; ""7.4 Characterization of plasmid clones""; ""8: Polymerase Chain Reaction""; ""8.1 The PCR reaction""; ""8.2 PCR in practice""; ""8.3 Cloning PCR products""; ""8.4 Long-range PCR""; ""8.5 Reverse-transcription PCR""; ""8.6 Rapid amplification of cDNA ends""; ""8.7 Quantitative PCR""; ""8.8 Applications of PCR""; ""9: Characterization of a Cloned Gene""; ""9.1 DNA sequencing""; ""9.2 Databank entries and annotation""; ""9.3 Sequence analysis"" ""9.4 Sequence comparisons""""9.5 Protein structure""; ""9.6 Confirming gene function""; ""10: Analysis of Gene Expression""; ""10.1 Analysing transcription""; ""10.2 Methods for studying the promoter""; ""10.3 Regulatory elements and DNA-binding proteins""; ""10.4 Translational analysis""; ""11: Products from Native and Manipulated Cloned Genes""; ""11.1 Factors affecting expression of cloned genes""; ""11.2 Expression of cloned genes in bacteria""; ""11.3 Expression in eukaryotic host cells""; ""11.4 Adding tags and signals""; ""11.5 In vitro mutagenesis""; ""11.6 Vaccines"" ""12: Genomic Analysis""""12.1 Genome sequencing""; ""12.2 Analysis and annotation""; ""12.3 Comparing genomes""; ""12.4 Genome browsers""; ""12.5 Relating genes and functions: genetic and physical maps""; ""12.6 Transposon mutagenesis and other screening techniques""; ""12.7 Conclusion""; ""13: Analysis of Genetic Variation""; ""13.1 Single nucleotide polymorphisms""; ""13.2 Larger-scale variations""; ""13.3 Other methods for studying variation""; ""13.4 Human genetic diseases""; ""13.5 Molecular phylogeny""; ""14: Post-genomic Analysis""; ""14.1 Analysing transcription; transcriptomes"" ""14.2 Array-based methods"" |
Record Nr. | UNINA-9910830445503321 |
Dale Jeremy (Jeremy W.)
![]() |
||
Hoboken, : Wiley, 2008 | ||
![]() | ||
Lo trovi qui: Univ. Federico II | ||
|
Gene reports |
Pubbl/distr/stampa | [New York, NY] : , : Elsevier Inc., , [2015]- |
Descrizione fisica | 1 online resource |
Soggetto topico |
Genetic engineering
Genetics Genetic Engineering Gene Expression |
Soggetto genere / forma |
Periodical
Periodicals. |
Soggetto non controllato | Genetics |
ISSN | 2452-0144 |
Formato | Materiale a stampa ![]() |
Livello bibliografico | Periodico |
Lingua di pubblicazione | eng |
Record Nr. | UNINA-9910231353003321 |
[New York, NY] : , : Elsevier Inc., , [2015]- | ||
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Lo trovi qui: Univ. Federico II | ||
|
Gene reports |
Pubbl/distr/stampa | [New York, NY] : , : Elsevier Inc., , [2015]- |
Descrizione fisica | 1 online resource |
Soggetto topico |
Genetic engineering
Genetics Genetic Engineering Gene Expression |
Soggetto genere / forma |
Periodical
Periodicals. |
Soggetto non controllato | Genetics |
ISSN | 2452-0144 |
Formato | Materiale a stampa ![]() |
Livello bibliografico | Periodico |
Lingua di pubblicazione | eng |
Record Nr. | UNINA-9910770292103321 |
[New York, NY] : , : Elsevier Inc., , [2015]- | ||
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Lo trovi qui: Univ. Federico II | ||
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Gene Therapy for Cartilage and Bone Tissue Engineering / / by Yu-Chen Hu |
Autore | Hu Yu-Chen |
Edizione | [1st ed. 2014.] |
Pubbl/distr/stampa | Berlin, Heidelberg : , : Springer Berlin Heidelberg : , : Imprint : Springer, , 2014 |
Descrizione fisica | 1 online resource (94 p.) |
Disciplina | 616.042 |
Collana | SpringerBriefs in Bioengineering |
Soggetto topico |
Biomedical engineering
Genetic engineering Gene therapy Regenerative medicine Tissue engineering Stem cells Biomedical Engineering and Bioengineering Genetic Engineering Gene Therapy Regenerative Medicine/Tissue Engineering Stem Cells |
ISBN | 3-642-53923-8 |
Formato | Materiale a stampa ![]() |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto | Bone and Cartilage Tissue Engineering -- Viral Gene Therapy Vectors -- Gene Therapy for Bone Tissue Engineering -- Gene Therapy for Cartilage Tissue Engineering -- Conclusions and Perspectives. |
Record Nr. | UNINA-9910299720703321 |
Hu Yu-Chen
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Berlin, Heidelberg : , : Springer Berlin Heidelberg : , : Imprint : Springer, , 2014 | ||
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Lo trovi qui: Univ. Federico II | ||
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Genetics of the Mouse / / by Jean Louis Guénet, Fernando Benavides, Jean-Jacques Panthier, Xavier Montagutelli |
Autore | Guénet Jean Louis |
Edizione | [1st ed. 2015.] |
Pubbl/distr/stampa | Berlin, Heidelberg : , : Springer Berlin Heidelberg : , : Imprint : Springer, , 2015 |
Descrizione fisica | 1 online resource (417 p.) |
Disciplina |
570
591.35 611.01816 616.027 660.65 |
Soggetto topico |
Animal genetics
Animal models in research Transgenic organisms Gene expression Genetic engineering Animal Genetics and Genomics Animal Models Transgenics Gene Expression Genetic Engineering |
ISBN | 3-662-44287-6 |
Formato | Materiale a stampa ![]() |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto | Origins of the Laboratory Mouse -- Basic Concepts of Reproductive Biology And Genetics -- Cytogenetics -- Gene Mapping -- The Mouse Genome -- Epigenetic Control of Genome Expression -- Mutations and Experimental Mutagenesis -- Transgenesis and Transgenic Animals -- The Different Categories of Genetically Standardized Populations of Laboratory Mice -- Quantitative Traits and Quantitative Genetics. |
Record Nr. | UNINA-9910298288303321 |
Guénet Jean Louis
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Berlin, Heidelberg : , : Springer Berlin Heidelberg : , : Imprint : Springer, , 2015 | ||
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Lo trovi qui: Univ. Federico II | ||
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Horizontal Gene Transfer : Breaking Borders Between Living Kingdoms / / edited by Tomás G. Villa, Miguel Viñas |
Edizione | [1st ed. 2019.] |
Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2019 |
Descrizione fisica | 1 online resource (422 pages) |
Disciplina |
574.873282
572.877 |
Soggetto topico |
Genetics
Drug resistance Evolutionary biology Microbial ecology Medical genetics Genetic engineering Genetics and Genomics Drug Resistance Evolutionary Biology Microbial Ecology Gene Function Genetic Engineering |
ISBN | 3-030-21862-7 |
Formato | Materiale a stampa ![]() |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto | Part 1: Horizontal gene transfer among bacteria and bacteriophages -- Chapter 1: Horizontal gene transfer in bacteria, an overview of the mechanisms involved -- Chapter 2: Alternative ways to exchange DNA: unconventional conjugation among bacteria -- Chapter 3: Horizontal gene transfer between bacteriophages and bacteria: Antibiotic resistances and toxin production -- Chapter 4: Genomic islands and the evolution of multidrug-resistant bacteria Mario Juhas -- Chapter 5: Horizontal gene transfer and genome evolution in the phylum Actinobacteria -- Chapter 6: Photobacterium damselae: How horizontal gene transfer shaped two different pathogenic lifestyles in a marine bacterium -- Part 2: Horizontal gene transfer between bacteria and animals, plants, amoeba and fungi -- chapter 7: Horizontal gene transfer in Metazoa: Examples and Methods -- Chapter 8: Horizontal gene transfer between Wolbachia and animals -- Chapter 9: Horizontal gene transfer in obligate parasites -- Chapter 10: Association between Horizontal gene transfer and Adaptation of gastric human pathogen Helicobacter pylori to host -- Chapter 11: The Rhizobiaceae bacteria transferring genes to higher plants Martha -- Chapter 12: Role of horizontal gene transfer in evolution of plant genome -- Chapter 13: Fungal horizontal gene transfer: a history beyond the Phylogenetic Kingdoms -- Chapter 14: Transfer of secondary metabolite gene clusters: assembly and reorganization ofthe b-lactam gene cluster from bacteria to fungi and arthropods -- Chapter 15: Horizontal gene transfer Among Neisseria species and humans -- Chapter 16: Implications of Lateral or Horizontal Gene Transfer from Bacteria to the Human Gastro-Intestinal System for Cancer Development and Treatment -- Chapter 17: Role of Horizontal Gene Transfer in Cancer Progression. . |
Record Nr. | UNINA-9910349447603321 |
Cham : , : Springer International Publishing : , : Imprint : Springer, , 2019 | ||
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Lo trovi qui: Univ. Federico II | ||
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Human embryonic stem cells / edited by J. Odorico, S.-C. Zhang, R. Pedersen |
Pubbl/distr/stampa | Oxon, UK : BIOS Scientific, 2005 |
Descrizione fisica | xxii, 391 p. : ill. ; 24 cm |
Disciplina | 612.646 |
Altri autori (Persone) |
Odorico, Jon S.
Zhang, Su-Chun Pedersen, Roger A. |
Soggetto topico |
Embryonic stem cells
Human cell culture Embryo Research Stem Cells - Physiology Embryo - Cytology Genetic Engineering |
ISBN | 9781859962787 |
Formato | Materiale a stampa ![]() |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Record Nr. | UNISALENTO-991003053819707536 |
Oxon, UK : BIOS Scientific, 2005 | ||
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Lo trovi qui: Univ. del Salento | ||
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Human Enhancement [[electronic resource]] |
Autore | Bostrom Nick |
Pubbl/distr/stampa | Oxford University Press, UK, 2009 |
Descrizione fisica | 1 online resource (432 p.) |
Disciplina |
174.29
610.1/9 |
Altri autori (Persone) | SavulescuJulian |
Soggetto topico |
Biomedical Enhancement
Genetic engineering Medical innovations Prenatal diagnosis Medical innovations - Social aspects Medical ethics Genetic Engineering Ethics Prenatal Diagnosis Morals Biomedical Technology Diagnostic Techniques, Obstetrical and Gynecological Investigative Techniques Genetic Techniques Psychology, Social Technology Diagnostic Techniques and Procedures Technology, Industry, and Agriculture Diagnosis Behavior and Behavior Mechanisms Psychiatry Social Medicine Public Health Health & Biological Sciences |
Soggetto genere / forma | Electronic books. |
ISBN | 0-19-155960-1 |
Formato | Materiale a stampa ![]() |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto |
Contents; Acknowledgements; Introduction: Human Enhancement Ethics: The State of the Debate; Part I. Human Enhancement in General; 1. Can Anyone Really Be Talking About Ethically Modifying Human Nature?; 2. What's Taxonomy Got to Do with It? ''Species Integrity,'' Human Rights, and Science Policy; 3. Should We Improve Human Nature? An Interrogation from an Asian Perspective; 4. The Case Against Perfection: What's Wrong with Designer Children, Bionic Athletes, and Genetic Engineering; 5. What Is and Is Not Wrong With Enhancement?; 6. Enhancements Are a Moral Obligation; 7. Playing God
8. Toward a More Fruitful Debate About Enhancement9. Good, Better, or Best?; 10. The Human Prejudice and the Moral Status of Enhanced Beings: What Do We Owe the Gods?; Part II. Specific Enhancements; 11. Is Selection of Children Wrong?; 12. Parental Choice and Human Improvement; 13. Reasons Against the Selection of Life: From Japan's Experience of Prenatal Genetic Diagnosis; 14. Medical Enhancement and the Ethos of Elite Sport; 15. Life Enhancement Technologies: Significance of Social Category Membership 16. Paternalism in the Age of Cognitive Enhancement: Do Civil Liberties Presuppose Roughly Equal Mental Ability?17. Enhancing Our Truth Orientation; Part III. Enhancement as a Practical Challenge; 18. The Wisdom of Nature: An Evolutionary Heuristic for Human Enhancement; Index; A; B; C; D; E; F; G; H; I; J; K; L; M; N; O; P; R; S; T; U; V; W |
Record Nr. | UNINA-9910461060303321 |
Bostrom Nick
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Oxford University Press, UK, 2009 | ||
![]() | ||
Lo trovi qui: Univ. Federico II | ||
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Human Enhancement [[electronic resource]] |
Autore | Bostrom Nick |
Pubbl/distr/stampa | Oxford University Press, UK, 2009 |
Descrizione fisica | 1 online resource (432 p.) |
Disciplina |
174.29
610.1/9 |
Altri autori (Persone) | SavulescuJulian |
Soggetto topico |
Biomedical Enhancement
Genetic engineering Medical innovations Prenatal diagnosis Medical innovations - Social aspects Medical ethics Genetic Engineering Ethics Prenatal Diagnosis Morals Biomedical Technology Diagnostic Techniques, Obstetrical and Gynecological Investigative Techniques Genetic Techniques Psychology, Social Technology Diagnostic Techniques and Procedures Technology, Industry, and Agriculture Diagnosis Behavior and Behavior Mechanisms Psychiatry Social Medicine Public Health Health & Biological Sciences |
ISBN |
1-383-04439-2
0-19-155960-1 |
Classificazione | 44.02 |
Formato | Materiale a stampa ![]() |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto |
Contents; Acknowledgements; Introduction: Human Enhancement Ethics: The State of the Debate; Part I. Human Enhancement in General; 1. Can Anyone Really Be Talking About Ethically Modifying Human Nature?; 2. What's Taxonomy Got to Do with It? ''Species Integrity,'' Human Rights, and Science Policy; 3. Should We Improve Human Nature? An Interrogation from an Asian Perspective; 4. The Case Against Perfection: What's Wrong with Designer Children, Bionic Athletes, and Genetic Engineering; 5. What Is and Is Not Wrong With Enhancement?; 6. Enhancements Are a Moral Obligation; 7. Playing God
8. Toward a More Fruitful Debate About Enhancement9. Good, Better, or Best?; 10. The Human Prejudice and the Moral Status of Enhanced Beings: What Do We Owe the Gods?; Part II. Specific Enhancements; 11. Is Selection of Children Wrong?; 12. Parental Choice and Human Improvement; 13. Reasons Against the Selection of Life: From Japan's Experience of Prenatal Genetic Diagnosis; 14. Medical Enhancement and the Ethos of Elite Sport; 15. Life Enhancement Technologies: Significance of Social Category Membership 16. Paternalism in the Age of Cognitive Enhancement: Do Civil Liberties Presuppose Roughly Equal Mental Ability?17. Enhancing Our Truth Orientation; Part III. Enhancement as a Practical Challenge; 18. The Wisdom of Nature: An Evolutionary Heuristic for Human Enhancement; Index; A; B; C; D; E; F; G; H; I; J; K; L; M; N; O; P; R; S; T; U; V; W |
Record Nr. | UNINA-9910797762703321 |
Bostrom Nick
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Oxford University Press, UK, 2009 | ||
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Lo trovi qui: Univ. Federico II | ||
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