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Medical and Biomedical Applications of Shock Waves [[electronic resource] /] / by Achim M. Loske
Medical and Biomedical Applications of Shock Waves [[electronic resource] /] / by Achim M. Loske
Autore Loske Achim M
Edizione [1st ed. 2017.]
Pubbl/distr/stampa Cham : , : Springer International Publishing : , : Imprint : Springer, , 2017
Descrizione fisica 1 online resource (XXIII, 378 p. 198 illus., 184 illus. in color.)
Disciplina 533.293
Collana Shock Wave and High Pressure Phenomena
Soggetto topico Acoustics
Radiology
Biomedical engineering
Urology
Gene therapy
Ultrasound
Biomedical Engineering and Bioengineering
Gene Therapy
ISBN 9783319475707
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Introduction -- Brief Historical Background -- Shock Waves as used in Biomedical Applications -- Shock Wave Interaction with Matter -- Shock Wave Lithotripsy -- Extracorporeal Shock Wave Therapy -- Novel uses and Potential Applicatitions.
Record Nr. UNINA-9910155300603321
Loske Achim M  
Cham : , : Springer International Publishing : , : Imprint : Springer, , 2017
Materiale a stampa
Lo trovi qui: Univ. Federico II
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Metabolomics: From Fundamentals to Clinical Applications [[electronic resource] /] / edited by Alessandra Sussulini
Metabolomics: From Fundamentals to Clinical Applications [[electronic resource] /] / edited by Alessandra Sussulini
Edizione [1st ed. 2017.]
Pubbl/distr/stampa Cham : , : Springer International Publishing : , : Imprint : Springer, , 2017
Descrizione fisica 1 online resource (X, 350 p. 56 illus., 54 illus. in color.)
Disciplina 570.285
Collana Proteomics, Metabolomics, Interactomics and Systems Biology
Soggetto topico Metabolism
Gene therapy
Medical genetics
Metabolomics
Gene Therapy
Gene Function
ISBN 3-319-47656-4
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Part I: Fundamentals and analytical methodologies in metabolomics -- 1. Metabolomics: definitions and significance in systems biology -- 2. Collection and preparation of clinical samples for metabolomics -- 3. NMR strategies in metabolomics -- 5. Strategies involving MS combined with chromatography in metabolomics -- 6.MS combined with capillary electrophoresis in metabolomics -- Part II: Statistical analysis and data interpretation -- 7. Data pretreatment: How to prepare a metabolomics dataset for statistical analysis? -- 8. Chemometrics in metabolomics -- Understanding metabolomics data: Metabolite identification and biological relevance -- Part III: Applications and future trends of metabolomics in clinical cases -- 9. Applications of metabolomics in cancer studies -- 10. Chronic diseases and lifestyle biomarkers identification by metabolomics -- 11. Metabolomics in neurological and psychiatric diseases -- 12. Metabolite profiling by MS imaging -- 13. Single cell metabolomics .
Record Nr. UNINA-9910163043603321
Cham : , : Springer International Publishing : , : Imprint : Springer, , 2017
Materiale a stampa
Lo trovi qui: Univ. Federico II
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MicroRNA Detection and Pathological Functions [[electronic resource] /] / by Xueji Zhang, Haifeng Dong, Yaping Tian
MicroRNA Detection and Pathological Functions [[electronic resource] /] / by Xueji Zhang, Haifeng Dong, Yaping Tian
Autore Zhang Xueji
Edizione [1st ed. 2015.]
Pubbl/distr/stampa Berlin, Heidelberg : , : Springer Berlin Heidelberg : , : Imprint : Springer, , 2015
Descrizione fisica 1 online resource (108 p.)
Disciplina 572.88
Collana SpringerBriefs in Molecular Science
Soggetto topico Analytical chemistry
Cancer research
Nucleic acids
Gene therapy
Analytical Chemistry
Cancer Research
Nucleic Acid Chemistry
Gene Therapy
ISBN 3-662-47293-7
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Introduction -- miRNAs Biology in Pathological Processes -- Conventional MiRNA Detection Strategies -- MiRNA Electrochemical Detection -- MiRNA Optical Detection.- Other Emerging MiRNA Detection Strategies -- Intracellular and Organic miRNA in Situ Detection -- Summary and Prospects.
Record Nr. UNINA-9910298633903321
Zhang Xueji  
Berlin, Heidelberg : , : Springer Berlin Heidelberg : , : Imprint : Springer, , 2015
Materiale a stampa
Lo trovi qui: Univ. Federico II
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Minicircle and miniplasmid DNA vectors [[electronic resource] ] : the future of nonviral and viral gene transfer / / edited by Martin Schleef
Minicircle and miniplasmid DNA vectors [[electronic resource] ] : the future of nonviral and viral gene transfer / / edited by Martin Schleef
Pubbl/distr/stampa Weinheim, Germany, : Wiley-Blackwell, 2013
Descrizione fisica 1 online resource (259 p.)
Disciplina 615.895
Altri autori (Persone) SchleefM (Martin)
Soggetto topico Gene therapy
Genetic vectors
Plasmids
ISBN 3-527-67042-4
1-299-24148-4
3-527-67043-2
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Minicircle and Miniplasmid DNA Vectors: The Future of Non-Viral and Viral Gene Transfer; Contents; List of Contributors; Preface; 1 Minicircle Patents: A Short IP Overview of Optimizing Nonviral DNA Vectors; 2 Operator-Repressor Titration: Stable Plasmid Maintenance without Selectable Marker Genes; 2.1 Introduction; 2.2 Antibiotics and Metabolic Burden; 2.3 The Mechanism of ORT; 2.4 ORT Strain Development; 2.5 ORT Miniplasmids; 2.6 DNA Vaccine and Gene Therapy Vectors; 2.7 ORT-VAC: Plasmid-Based Vaccine Delivery Using Salmonella enterica; 2.8 Recombinant Protein Expression
2.9 Conclusions and Future DevelopmentsReferences; 3 Selection by RNA-RNA Interaction: Maximally Minimized Antibiotic Resistance-Free Plasmids; 3.1 Gene Therapy and DNA Vaccines: Emerging Technologies; 3.1.1 Therapeutic Plasmids: General Design Principles; 3.2 Therapeutic Plasmids: Novel Design and the Problem of Selection; 3.2.1 Replication Control of ColE1-Type Plasmids as an Alternative Selection Marker; 3.2.2 The MINIback Concept: Selection by RNA-RNA Interaction; 3.2.3 Improved Production Processes by MINIback Plasmids; 3.2.4 Improving Sequence Composition; 3.2.5 Efficient Gene Transfer
3.3 Conclusions Acknowledgments; References; 4 Plasmid-Based Medicinal Products - Focus on pFAR: A Miniplasmid Free of Antibiotic Resistance Markers; 4.1 Introduction: Rationale for the Development of Biosafe DNA Plasmid Vectors; 4.2 Specific Requirements for the Use of DNA Product as Medicines; 4.2.1 Requirements for Plasmid Quality and Purity; 4.2.2 Requirements for the Removal of Antibiotic Resistance Markers from Plasmid DNA; 4.2.2.1 Requirements for Biosafe Plasmids; 4.2.2.2 Positive Impact on the Removal of Antibiotic Resistance Markers
4.2.2.3 Effect of Plasmid Size on Gene Transfer Efficiency In Vitro and In Vivo 4.3 Nonviral Gene Vectors Devoid of Antibiotic Resistance Markers; 4.3.1 Generalities; 4.3.2 Selection Systems Devoid of Antibiotic Resistance Markers; 4.3.2.1 Complementation of Host Auxotrophy by a Function-Encoded Plasmid; 4.3.2.2 The Operator-Repressor Titration (ORT) System; 4.3.2.3 Protein-Based Antidote/Poison Selection Systems; 4.3.2.4 RNA-Based Selection Marker; 4.3.2.5 Suppression of a Nonsense Mutation; 4.4 The pFAR Plasmid Family; 4.4.1 Description of the Antibiotic-Free Selection System
4.4.2 pFAR Vectors Promote Efficient Expression in Several Types of Mammalian Cells 4.4.2.1 In Vitro Transfection Study; 4.4.2.2 In Vivo Transfection Studies; 4.4.3 Concluding Remarks on the pFAR4 Biosafe Miniplasmid; 4.5 Concluding Remarks and Perspectives; Acknowledgments; References; 5 Plasmid DNA Concatemers: Influence of Plasmid Structure on Transfection Efficiency; 5.1 Introduction; 5.2 Plasmid DNA Topology and Size; 5.3 Plasmid DNA Concatemers; 5.4 Conclusions; Acknowledgments; References; 6 Analytical Tools in Minicircle Production; 6.1 Introduction
6.1.1 Gene Transfer for Therapy, Vaccination, and Stem Cells
Record Nr. UNINA-9910141646903321
Weinheim, Germany, : Wiley-Blackwell, 2013
Materiale a stampa
Lo trovi qui: Univ. Federico II
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Minicircle and miniplasmid DNA vectors [[electronic resource] ] : the future of nonviral and viral gene transfer / / edited by Martin Schleef
Minicircle and miniplasmid DNA vectors [[electronic resource] ] : the future of nonviral and viral gene transfer / / edited by Martin Schleef
Edizione [1st ed.]
Pubbl/distr/stampa Weinheim, Germany, : Wiley-Blackwell, 2013
Descrizione fisica 1 online resource (259 p.)
Disciplina 615.895
Altri autori (Persone) SchleefM (Martin)
Soggetto topico Gene therapy
Genetic vectors
Plasmids
ISBN 3-527-67042-4
1-299-24148-4
3-527-67043-2
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Minicircle and Miniplasmid DNA Vectors: The Future of Non-Viral and Viral Gene Transfer; Contents; List of Contributors; Preface; 1 Minicircle Patents: A Short IP Overview of Optimizing Nonviral DNA Vectors; 2 Operator-Repressor Titration: Stable Plasmid Maintenance without Selectable Marker Genes; 2.1 Introduction; 2.2 Antibiotics and Metabolic Burden; 2.3 The Mechanism of ORT; 2.4 ORT Strain Development; 2.5 ORT Miniplasmids; 2.6 DNA Vaccine and Gene Therapy Vectors; 2.7 ORT-VAC: Plasmid-Based Vaccine Delivery Using Salmonella enterica; 2.8 Recombinant Protein Expression
2.9 Conclusions and Future DevelopmentsReferences; 3 Selection by RNA-RNA Interaction: Maximally Minimized Antibiotic Resistance-Free Plasmids; 3.1 Gene Therapy and DNA Vaccines: Emerging Technologies; 3.1.1 Therapeutic Plasmids: General Design Principles; 3.2 Therapeutic Plasmids: Novel Design and the Problem of Selection; 3.2.1 Replication Control of ColE1-Type Plasmids as an Alternative Selection Marker; 3.2.2 The MINIback Concept: Selection by RNA-RNA Interaction; 3.2.3 Improved Production Processes by MINIback Plasmids; 3.2.4 Improving Sequence Composition; 3.2.5 Efficient Gene Transfer
3.3 Conclusions Acknowledgments; References; 4 Plasmid-Based Medicinal Products - Focus on pFAR: A Miniplasmid Free of Antibiotic Resistance Markers; 4.1 Introduction: Rationale for the Development of Biosafe DNA Plasmid Vectors; 4.2 Specific Requirements for the Use of DNA Product as Medicines; 4.2.1 Requirements for Plasmid Quality and Purity; 4.2.2 Requirements for the Removal of Antibiotic Resistance Markers from Plasmid DNA; 4.2.2.1 Requirements for Biosafe Plasmids; 4.2.2.2 Positive Impact on the Removal of Antibiotic Resistance Markers
4.2.2.3 Effect of Plasmid Size on Gene Transfer Efficiency In Vitro and In Vivo 4.3 Nonviral Gene Vectors Devoid of Antibiotic Resistance Markers; 4.3.1 Generalities; 4.3.2 Selection Systems Devoid of Antibiotic Resistance Markers; 4.3.2.1 Complementation of Host Auxotrophy by a Function-Encoded Plasmid; 4.3.2.2 The Operator-Repressor Titration (ORT) System; 4.3.2.3 Protein-Based Antidote/Poison Selection Systems; 4.3.2.4 RNA-Based Selection Marker; 4.3.2.5 Suppression of a Nonsense Mutation; 4.4 The pFAR Plasmid Family; 4.4.1 Description of the Antibiotic-Free Selection System
4.4.2 pFAR Vectors Promote Efficient Expression in Several Types of Mammalian Cells 4.4.2.1 In Vitro Transfection Study; 4.4.2.2 In Vivo Transfection Studies; 4.4.3 Concluding Remarks on the pFAR4 Biosafe Miniplasmid; 4.5 Concluding Remarks and Perspectives; Acknowledgments; References; 5 Plasmid DNA Concatemers: Influence of Plasmid Structure on Transfection Efficiency; 5.1 Introduction; 5.2 Plasmid DNA Topology and Size; 5.3 Plasmid DNA Concatemers; 5.4 Conclusions; Acknowledgments; References; 6 Analytical Tools in Minicircle Production; 6.1 Introduction
6.1.1 Gene Transfer for Therapy, Vaccination, and Stem Cells
Record Nr. UNINA-9910813918003321
Weinheim, Germany, : Wiley-Blackwell, 2013
Materiale a stampa
Lo trovi qui: Univ. Federico II
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Molecular and Cellular Biology of Platelet Formation [[electronic resource] ] : Implications in Health and Disease / / edited by Harald Schulze, Joseph Italiano
Molecular and Cellular Biology of Platelet Formation [[electronic resource] ] : Implications in Health and Disease / / edited by Harald Schulze, Joseph Italiano
Edizione [1st ed. 2016.]
Pubbl/distr/stampa Cham : , : Springer International Publishing : , : Imprint : Springer, , 2016
Descrizione fisica 1 online resource (456 pages)
Disciplina 612.117
Soggetto topico Human physiology
Hematology
Cell biology
Gene therapy
Molecular biology
Blood transfusion
Human Physiology
Cell Biology
Gene Therapy
Molecular Medicine
Blood Transfusion Medicine
ISBN 3-319-39562-9
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto I. Thrombopoiesis  1. A short history of the platelet (N.N.) -- 2. Megakaryopoiesis and Platelet biogenesis (Italiano) -- 3. Transcription factors in MKs and platelets (Cantor / Tijssen & Ghavaert) -- 4. Platelet biogenesis in vivo and the Vascular Niche (Schulze). II. Platelet biology.- 5. Platelet contents (Hartwig) -- 6. Platelet signal transduction (Yonis / S. Watson) -- 7. Thrombosis (Bergmeier) -- 8. Platelets and coagulation (N.N.) -- 9. The platelet life span (Kile). III. Animal models   10. Platelets in mice and men (N.N) --   11. Animal models for platelet function (Nieswandt) -- 12. Other animal models /zebrafish (N.N.).     IV. Platelets in Health and Disease.- 13. Platelet parameters and function testing in the clinic (Schulze / Dame) -- 14. Atherothrombosis and Coronary Artery Disease (Nieswandt) -- 15. Thrombocytopenias and Thrombocytopathies (Ballmaier) -- 16. Platelets in myeloproliferative disorders and leukemia (N.N.) -- 17. Platelet Apheresis and Transfusions (N.N) -- 18. Platelet Biogenesis following Stem Cell Transplantation (N.N).
Record Nr. UNINA-9910163989503321
Cham : , : Springer International Publishing : , : Imprint : Springer, , 2016
Materiale a stampa
Lo trovi qui: Univ. Federico II
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Molecular diagnosis & therapy
Molecular diagnosis & therapy
Pubbl/distr/stampa Auckland, N.Z., : Adis International, ©2006-
Descrizione fisica 1 online resource
Disciplina 616.0756
Soggetto topico Molecular diagnosis
Biochemical markers
Gene therapy
Pharmacogenetics
Molecular Diagnostic Techniques
Biomarkers
Genetic Therapy
Soggetto genere / forma Periodical
Periodicals.
ISSN 1179-2000
Formato Materiale a stampa
Livello bibliografico Periodico
Lingua di pubblicazione eng
Altri titoli varianti Molecular diagnosis and therapy
Record Nr. UNISA-996217475303316
Auckland, N.Z., : Adis International, ©2006-
Materiale a stampa
Lo trovi qui: Univ. di Salerno
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Molecular diagnosis & therapy
Molecular diagnosis & therapy
Pubbl/distr/stampa Auckland, N.Z., : Adis International, ©2006-
Descrizione fisica 1 online resource
Disciplina 616.0756
Soggetto topico Molecular diagnosis
Biochemical markers
Gene therapy
Pharmacogenetics
Molecular Diagnostic Techniques
Biomarkers
Genetic Therapy
Soggetto genere / forma Periodical
Periodicals.
ISSN 1179-2000
Formato Materiale a stampa
Livello bibliografico Periodico
Lingua di pubblicazione eng
Altri titoli varianti Molecular diagnosis and therapy
Record Nr. UNINA-9910154513503321
Auckland, N.Z., : Adis International, ©2006-
Materiale a stampa
Lo trovi qui: Univ. Federico II
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Molecular therapy
Molecular therapy
Pubbl/distr/stampa San Diego, CA, : Academic Press, [2000]-
Disciplina 619
Soggetto topico Gene therapy
Molecular genetics
Genetic Therapy
Molecular Biology
Gene Transfer Techniques
Thérapie génique
Soggetto genere / forma Fulltext
Internet Resources.
Periodicals.
ISSN 1525-0024
Formato Materiale a stampa
Livello bibliografico Periodico
Lingua di pubblicazione eng
Altri titoli varianti Journal of the American Society of Gene Therapy
Official journal of the American Society of Gene & Cell Therapy
Record Nr. UNISA-996210050503316
San Diego, CA, : Academic Press, [2000]-
Materiale a stampa
Lo trovi qui: Univ. di Salerno
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Molecular therapy
Molecular therapy
Pubbl/distr/stampa San Diego, CA, : Academic Press, [2000]-
Disciplina 619
Soggetto topico Gene therapy
Molecular genetics
Genetic Therapy
Molecular Biology
Gene Transfer Techniques
Thérapie génique
Soggetto genere / forma Fulltext
Internet Resources.
Periodicals.
ISSN 1525-0024
Formato Materiale a stampa
Livello bibliografico Periodico
Lingua di pubblicazione eng
Altri titoli varianti Journal of the American Society of Gene Therapy
Official journal of the American Society of Gene & Cell Therapy
Record Nr. UNINA-9910140147903321
San Diego, CA, : Academic Press, [2000]-
Materiale a stampa
Lo trovi qui: Univ. Federico II
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