Medical and Biomedical Applications of Shock Waves [[electronic resource] /] / by Achim M. Loske |
Autore | Loske Achim M |
Edizione | [1st ed. 2017.] |
Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2017 |
Descrizione fisica | 1 online resource (XXIII, 378 p. 198 illus., 184 illus. in color.) |
Disciplina | 533.293 |
Collana | Shock Wave and High Pressure Phenomena |
Soggetto topico |
Acoustics
Radiology Biomedical engineering Urology Gene therapy Ultrasound Biomedical Engineering and Bioengineering Gene Therapy |
ISBN | 9783319475707 |
Formato | Materiale a stampa ![]() |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto | Introduction -- Brief Historical Background -- Shock Waves as used in Biomedical Applications -- Shock Wave Interaction with Matter -- Shock Wave Lithotripsy -- Extracorporeal Shock Wave Therapy -- Novel uses and Potential Applicatitions. |
Record Nr. | UNINA-9910155300603321 |
Loske Achim M
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Cham : , : Springer International Publishing : , : Imprint : Springer, , 2017 | ||
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Lo trovi qui: Univ. Federico II | ||
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Metabolomics: From Fundamentals to Clinical Applications [[electronic resource] /] / edited by Alessandra Sussulini |
Edizione | [1st ed. 2017.] |
Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2017 |
Descrizione fisica | 1 online resource (X, 350 p. 56 illus., 54 illus. in color.) |
Disciplina | 570.285 |
Collana | Proteomics, Metabolomics, Interactomics and Systems Biology |
Soggetto topico |
Metabolism
Gene therapy Medical genetics Metabolomics Gene Therapy Gene Function |
ISBN | 3-319-47656-4 |
Formato | Materiale a stampa ![]() |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto | Part I: Fundamentals and analytical methodologies in metabolomics -- 1. Metabolomics: definitions and significance in systems biology -- 2. Collection and preparation of clinical samples for metabolomics -- 3. NMR strategies in metabolomics -- 5. Strategies involving MS combined with chromatography in metabolomics -- 6.MS combined with capillary electrophoresis in metabolomics -- Part II: Statistical analysis and data interpretation -- 7. Data pretreatment: How to prepare a metabolomics dataset for statistical analysis? -- 8. Chemometrics in metabolomics -- Understanding metabolomics data: Metabolite identification and biological relevance -- Part III: Applications and future trends of metabolomics in clinical cases -- 9. Applications of metabolomics in cancer studies -- 10. Chronic diseases and lifestyle biomarkers identification by metabolomics -- 11. Metabolomics in neurological and psychiatric diseases -- 12. Metabolite profiling by MS imaging -- 13. Single cell metabolomics . |
Record Nr. | UNINA-9910163043603321 |
Cham : , : Springer International Publishing : , : Imprint : Springer, , 2017 | ||
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Lo trovi qui: Univ. Federico II | ||
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MicroRNA Detection and Pathological Functions [[electronic resource] /] / by Xueji Zhang, Haifeng Dong, Yaping Tian |
Autore | Zhang Xueji |
Edizione | [1st ed. 2015.] |
Pubbl/distr/stampa | Berlin, Heidelberg : , : Springer Berlin Heidelberg : , : Imprint : Springer, , 2015 |
Descrizione fisica | 1 online resource (108 p.) |
Disciplina | 572.88 |
Collana | SpringerBriefs in Molecular Science |
Soggetto topico |
Analytical chemistry
Cancer research Nucleic acids Gene therapy Analytical Chemistry Cancer Research Nucleic Acid Chemistry Gene Therapy |
ISBN | 3-662-47293-7 |
Formato | Materiale a stampa ![]() |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto | Introduction -- miRNAs Biology in Pathological Processes -- Conventional MiRNA Detection Strategies -- MiRNA Electrochemical Detection -- MiRNA Optical Detection.- Other Emerging MiRNA Detection Strategies -- Intracellular and Organic miRNA in Situ Detection -- Summary and Prospects. |
Record Nr. | UNINA-9910298633903321 |
Zhang Xueji
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Berlin, Heidelberg : , : Springer Berlin Heidelberg : , : Imprint : Springer, , 2015 | ||
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Lo trovi qui: Univ. Federico II | ||
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Minicircle and miniplasmid DNA vectors [[electronic resource] ] : the future of nonviral and viral gene transfer / / edited by Martin Schleef |
Pubbl/distr/stampa | Weinheim, Germany, : Wiley-Blackwell, 2013 |
Descrizione fisica | 1 online resource (259 p.) |
Disciplina | 615.895 |
Altri autori (Persone) | SchleefM (Martin) |
Soggetto topico |
Gene therapy
Genetic vectors Plasmids |
ISBN |
3-527-67042-4
1-299-24148-4 3-527-67043-2 |
Formato | Materiale a stampa ![]() |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto |
Minicircle and Miniplasmid DNA Vectors: The Future of Non-Viral and Viral Gene Transfer; Contents; List of Contributors; Preface; 1 Minicircle Patents: A Short IP Overview of Optimizing Nonviral DNA Vectors; 2 Operator-Repressor Titration: Stable Plasmid Maintenance without Selectable Marker Genes; 2.1 Introduction; 2.2 Antibiotics and Metabolic Burden; 2.3 The Mechanism of ORT; 2.4 ORT Strain Development; 2.5 ORT Miniplasmids; 2.6 DNA Vaccine and Gene Therapy Vectors; 2.7 ORT-VAC: Plasmid-Based Vaccine Delivery Using Salmonella enterica; 2.8 Recombinant Protein Expression
2.9 Conclusions and Future DevelopmentsReferences; 3 Selection by RNA-RNA Interaction: Maximally Minimized Antibiotic Resistance-Free Plasmids; 3.1 Gene Therapy and DNA Vaccines: Emerging Technologies; 3.1.1 Therapeutic Plasmids: General Design Principles; 3.2 Therapeutic Plasmids: Novel Design and the Problem of Selection; 3.2.1 Replication Control of ColE1-Type Plasmids as an Alternative Selection Marker; 3.2.2 The MINIback Concept: Selection by RNA-RNA Interaction; 3.2.3 Improved Production Processes by MINIback Plasmids; 3.2.4 Improving Sequence Composition; 3.2.5 Efficient Gene Transfer 3.3 Conclusions Acknowledgments; References; 4 Plasmid-Based Medicinal Products - Focus on pFAR: A Miniplasmid Free of Antibiotic Resistance Markers; 4.1 Introduction: Rationale for the Development of Biosafe DNA Plasmid Vectors; 4.2 Specific Requirements for the Use of DNA Product as Medicines; 4.2.1 Requirements for Plasmid Quality and Purity; 4.2.2 Requirements for the Removal of Antibiotic Resistance Markers from Plasmid DNA; 4.2.2.1 Requirements for Biosafe Plasmids; 4.2.2.2 Positive Impact on the Removal of Antibiotic Resistance Markers 4.2.2.3 Effect of Plasmid Size on Gene Transfer Efficiency In Vitro and In Vivo 4.3 Nonviral Gene Vectors Devoid of Antibiotic Resistance Markers; 4.3.1 Generalities; 4.3.2 Selection Systems Devoid of Antibiotic Resistance Markers; 4.3.2.1 Complementation of Host Auxotrophy by a Function-Encoded Plasmid; 4.3.2.2 The Operator-Repressor Titration (ORT) System; 4.3.2.3 Protein-Based Antidote/Poison Selection Systems; 4.3.2.4 RNA-Based Selection Marker; 4.3.2.5 Suppression of a Nonsense Mutation; 4.4 The pFAR Plasmid Family; 4.4.1 Description of the Antibiotic-Free Selection System 4.4.2 pFAR Vectors Promote Efficient Expression in Several Types of Mammalian Cells 4.4.2.1 In Vitro Transfection Study; 4.4.2.2 In Vivo Transfection Studies; 4.4.3 Concluding Remarks on the pFAR4 Biosafe Miniplasmid; 4.5 Concluding Remarks and Perspectives; Acknowledgments; References; 5 Plasmid DNA Concatemers: Influence of Plasmid Structure on Transfection Efficiency; 5.1 Introduction; 5.2 Plasmid DNA Topology and Size; 5.3 Plasmid DNA Concatemers; 5.4 Conclusions; Acknowledgments; References; 6 Analytical Tools in Minicircle Production; 6.1 Introduction 6.1.1 Gene Transfer for Therapy, Vaccination, and Stem Cells |
Record Nr. | UNINA-9910141646903321 |
Weinheim, Germany, : Wiley-Blackwell, 2013 | ||
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Lo trovi qui: Univ. Federico II | ||
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Minicircle and miniplasmid DNA vectors [[electronic resource] ] : the future of nonviral and viral gene transfer / / edited by Martin Schleef |
Edizione | [1st ed.] |
Pubbl/distr/stampa | Weinheim, Germany, : Wiley-Blackwell, 2013 |
Descrizione fisica | 1 online resource (259 p.) |
Disciplina | 615.895 |
Altri autori (Persone) | SchleefM (Martin) |
Soggetto topico |
Gene therapy
Genetic vectors Plasmids |
ISBN |
3-527-67042-4
1-299-24148-4 3-527-67043-2 |
Formato | Materiale a stampa ![]() |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto |
Minicircle and Miniplasmid DNA Vectors: The Future of Non-Viral and Viral Gene Transfer; Contents; List of Contributors; Preface; 1 Minicircle Patents: A Short IP Overview of Optimizing Nonviral DNA Vectors; 2 Operator-Repressor Titration: Stable Plasmid Maintenance without Selectable Marker Genes; 2.1 Introduction; 2.2 Antibiotics and Metabolic Burden; 2.3 The Mechanism of ORT; 2.4 ORT Strain Development; 2.5 ORT Miniplasmids; 2.6 DNA Vaccine and Gene Therapy Vectors; 2.7 ORT-VAC: Plasmid-Based Vaccine Delivery Using Salmonella enterica; 2.8 Recombinant Protein Expression
2.9 Conclusions and Future DevelopmentsReferences; 3 Selection by RNA-RNA Interaction: Maximally Minimized Antibiotic Resistance-Free Plasmids; 3.1 Gene Therapy and DNA Vaccines: Emerging Technologies; 3.1.1 Therapeutic Plasmids: General Design Principles; 3.2 Therapeutic Plasmids: Novel Design and the Problem of Selection; 3.2.1 Replication Control of ColE1-Type Plasmids as an Alternative Selection Marker; 3.2.2 The MINIback Concept: Selection by RNA-RNA Interaction; 3.2.3 Improved Production Processes by MINIback Plasmids; 3.2.4 Improving Sequence Composition; 3.2.5 Efficient Gene Transfer 3.3 Conclusions Acknowledgments; References; 4 Plasmid-Based Medicinal Products - Focus on pFAR: A Miniplasmid Free of Antibiotic Resistance Markers; 4.1 Introduction: Rationale for the Development of Biosafe DNA Plasmid Vectors; 4.2 Specific Requirements for the Use of DNA Product as Medicines; 4.2.1 Requirements for Plasmid Quality and Purity; 4.2.2 Requirements for the Removal of Antibiotic Resistance Markers from Plasmid DNA; 4.2.2.1 Requirements for Biosafe Plasmids; 4.2.2.2 Positive Impact on the Removal of Antibiotic Resistance Markers 4.2.2.3 Effect of Plasmid Size on Gene Transfer Efficiency In Vitro and In Vivo 4.3 Nonviral Gene Vectors Devoid of Antibiotic Resistance Markers; 4.3.1 Generalities; 4.3.2 Selection Systems Devoid of Antibiotic Resistance Markers; 4.3.2.1 Complementation of Host Auxotrophy by a Function-Encoded Plasmid; 4.3.2.2 The Operator-Repressor Titration (ORT) System; 4.3.2.3 Protein-Based Antidote/Poison Selection Systems; 4.3.2.4 RNA-Based Selection Marker; 4.3.2.5 Suppression of a Nonsense Mutation; 4.4 The pFAR Plasmid Family; 4.4.1 Description of the Antibiotic-Free Selection System 4.4.2 pFAR Vectors Promote Efficient Expression in Several Types of Mammalian Cells 4.4.2.1 In Vitro Transfection Study; 4.4.2.2 In Vivo Transfection Studies; 4.4.3 Concluding Remarks on the pFAR4 Biosafe Miniplasmid; 4.5 Concluding Remarks and Perspectives; Acknowledgments; References; 5 Plasmid DNA Concatemers: Influence of Plasmid Structure on Transfection Efficiency; 5.1 Introduction; 5.2 Plasmid DNA Topology and Size; 5.3 Plasmid DNA Concatemers; 5.4 Conclusions; Acknowledgments; References; 6 Analytical Tools in Minicircle Production; 6.1 Introduction 6.1.1 Gene Transfer for Therapy, Vaccination, and Stem Cells |
Record Nr. | UNINA-9910813918003321 |
Weinheim, Germany, : Wiley-Blackwell, 2013 | ||
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Lo trovi qui: Univ. Federico II | ||
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Molecular and Cellular Biology of Platelet Formation [[electronic resource] ] : Implications in Health and Disease / / edited by Harald Schulze, Joseph Italiano |
Edizione | [1st ed. 2016.] |
Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2016 |
Descrizione fisica | 1 online resource (456 pages) |
Disciplina | 612.117 |
Soggetto topico |
Human physiology
Hematology Cell biology Gene therapy Molecular biology Blood transfusion Human Physiology Cell Biology Gene Therapy Molecular Medicine Blood Transfusion Medicine |
ISBN | 3-319-39562-9 |
Formato | Materiale a stampa ![]() |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto | I. Thrombopoiesis 1. A short history of the platelet (N.N.) -- 2. Megakaryopoiesis and Platelet biogenesis (Italiano) -- 3. Transcription factors in MKs and platelets (Cantor / Tijssen & Ghavaert) -- 4. Platelet biogenesis in vivo and the Vascular Niche (Schulze). II. Platelet biology.- 5. Platelet contents (Hartwig) -- 6. Platelet signal transduction (Yonis / S. Watson) -- 7. Thrombosis (Bergmeier) -- 8. Platelets and coagulation (N.N.) -- 9. The platelet life span (Kile). III. Animal models 10. Platelets in mice and men (N.N) -- 11. Animal models for platelet function (Nieswandt) -- 12. Other animal models /zebrafish (N.N.). IV. Platelets in Health and Disease.- 13. Platelet parameters and function testing in the clinic (Schulze / Dame) -- 14. Atherothrombosis and Coronary Artery Disease (Nieswandt) -- 15. Thrombocytopenias and Thrombocytopathies (Ballmaier) -- 16. Platelets in myeloproliferative disorders and leukemia (N.N.) -- 17. Platelet Apheresis and Transfusions (N.N) -- 18. Platelet Biogenesis following Stem Cell Transplantation (N.N). |
Record Nr. | UNINA-9910163989503321 |
Cham : , : Springer International Publishing : , : Imprint : Springer, , 2016 | ||
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Lo trovi qui: Univ. Federico II | ||
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Molecular diagnosis & therapy |
Pubbl/distr/stampa | Auckland, N.Z., : Adis International, ©2006- |
Descrizione fisica | 1 online resource |
Disciplina | 616.0756 |
Soggetto topico |
Molecular diagnosis
Biochemical markers Gene therapy Pharmacogenetics Molecular Diagnostic Techniques Biomarkers Genetic Therapy |
Soggetto genere / forma |
Periodical
Periodicals. |
ISSN | 1179-2000 |
Formato | Materiale a stampa ![]() |
Livello bibliografico | Periodico |
Lingua di pubblicazione | eng |
Altri titoli varianti | Molecular diagnosis and therapy |
Record Nr. | UNISA-996217475303316 |
Auckland, N.Z., : Adis International, ©2006- | ||
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Lo trovi qui: Univ. di Salerno | ||
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Molecular diagnosis & therapy |
Pubbl/distr/stampa | Auckland, N.Z., : Adis International, ©2006- |
Descrizione fisica | 1 online resource |
Disciplina | 616.0756 |
Soggetto topico |
Molecular diagnosis
Biochemical markers Gene therapy Pharmacogenetics Molecular Diagnostic Techniques Biomarkers Genetic Therapy |
Soggetto genere / forma |
Periodical
Periodicals. |
ISSN | 1179-2000 |
Formato | Materiale a stampa ![]() |
Livello bibliografico | Periodico |
Lingua di pubblicazione | eng |
Altri titoli varianti | Molecular diagnosis and therapy |
Record Nr. | UNINA-9910154513503321 |
Auckland, N.Z., : Adis International, ©2006- | ||
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Lo trovi qui: Univ. Federico II | ||
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Molecular therapy |
Pubbl/distr/stampa | San Diego, CA, : Academic Press, [2000]- |
Disciplina | 619 |
Soggetto topico |
Gene therapy
Molecular genetics Genetic Therapy Molecular Biology Gene Transfer Techniques Thérapie génique |
Soggetto genere / forma |
Fulltext
Internet Resources. Periodicals. |
ISSN | 1525-0024 |
Formato | Materiale a stampa ![]() |
Livello bibliografico | Periodico |
Lingua di pubblicazione | eng |
Altri titoli varianti |
Journal of the American Society of Gene Therapy
Official journal of the American Society of Gene & Cell Therapy |
Record Nr. | UNISA-996210050503316 |
San Diego, CA, : Academic Press, [2000]- | ||
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Lo trovi qui: Univ. di Salerno | ||
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Molecular therapy |
Pubbl/distr/stampa | San Diego, CA, : Academic Press, [2000]- |
Disciplina | 619 |
Soggetto topico |
Gene therapy
Molecular genetics Genetic Therapy Molecular Biology Gene Transfer Techniques Thérapie génique |
Soggetto genere / forma |
Fulltext
Internet Resources. Periodicals. |
ISSN | 1525-0024 |
Formato | Materiale a stampa ![]() |
Livello bibliografico | Periodico |
Lingua di pubblicazione | eng |
Altri titoli varianti |
Journal of the American Society of Gene Therapy
Official journal of the American Society of Gene & Cell Therapy |
Record Nr. | UNINA-9910140147903321 |
San Diego, CA, : Academic Press, [2000]- | ||
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Lo trovi qui: Univ. Federico II | ||
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