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I Domain Integrins [[electronic resource] /] / edited by Donald Gullberg
| I Domain Integrins [[electronic resource] /] / edited by Donald Gullberg |
| Edizione | [1st ed. 2014.] |
| Pubbl/distr/stampa | Dordrecht : , : Springer Netherlands : , : Imprint : Springer, , 2014 |
| Descrizione fisica | 1 online resource (188 p.) |
| Disciplina | 572.68 |
| Collana | Advances in Experimental Medicine and Biology |
| Soggetto topico |
Medicine
Life sciences Medical genetics Medical biochemistry Biomedicine, general Life Sciences, general Gene Function Medical Biochemistry |
| ISBN | 94-017-9153-8 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Preface -- 1 Evolution of integrin I domains -- 2 Integrin a1b1 -- 3 Integrin a2b1 -- 4 Integrin a10b1- a collagen receptor critical in skeletal development -- 5 Integrin a11b1 – a major collagen receptor on fibroblastic cells -- 6 Regulation of integrin activity by phosphorylation -- 7 Integrin aEb7:molecular features and functional significance in the immune system -- 8 Structural aspects of integrins -- 9 Integrin recognition motifs in the human collagens -- 10 Cellular signalling by collagen-binding integrins -- 11 The therapeutic potential of I-domain integrins -- Index. |
| Record Nr. | UNINA-9910298351203321 |
| Dordrecht : , : Springer Netherlands : , : Imprint : Springer, , 2014 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Introduction to Biomolecular Structure and Biophysics [[electronic resource] ] : Basics of Biophysics / / edited by Gauri Misra
| Introduction to Biomolecular Structure and Biophysics [[electronic resource] ] : Basics of Biophysics / / edited by Gauri Misra |
| Edizione | [1st ed. 2017.] |
| Pubbl/distr/stampa | Singapore : , : Springer Singapore : , : Imprint : Springer, , 2017 |
| Descrizione fisica | 1 online resource (XVII, 274 p. 133 illus., 78 illus. in color.) |
| Disciplina | 610.28 |
| Soggetto topico |
Biomedical engineering
Biophysics Biological physics Nucleic acids Proteins Medical genetics Biomedical Engineering/Biotechnology Biological and Medical Physics, Biophysics Nucleic Acid Chemistry Protein Science Gene Function Protein-Ligand Interactions |
| ISBN | 981-10-4968-8 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Principles of protein structure and function -- Protein folding -- Nucleic acid structure and functions -- Higher order nucleic acid structures -- Molecular Interactions -- Lipid and membrane structures -- Chapter 7. Membrane biophysics -- Techniques in Biophysics -- Advance techniques in Biophysics. |
| Record Nr. | UNINA-9910253938003321 |
| Singapore : , : Springer Singapore : , : Imprint : Springer, , 2017 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Limits of Patentability [[electronic resource] ] : Plant Sciences, Stem Cells and Nucleic Acids / / by Andreas Hübel, Ulrich Storz, Aloys Hüttermann
| Limits of Patentability [[electronic resource] ] : Plant Sciences, Stem Cells and Nucleic Acids / / by Andreas Hübel, Ulrich Storz, Aloys Hüttermann |
| Autore | Hübel Andreas |
| Edizione | [1st ed. 2013.] |
| Pubbl/distr/stampa | Berlin, Heidelberg : , : Springer Berlin Heidelberg : , : Imprint : Springer, , 2013 |
| Descrizione fisica | 1 online resource (53 p.) |
| Disciplina | 346.0486 |
| Collana | SpringerBriefs in Biotech Patents |
| Soggetto topico |
Stem cells
Medical genetics Plant breeding Nucleic acids Genetic engineering Commercial law Stem Cells Gene Function Plant Breeding/Biotechnology Nucleic Acid Chemistry Genetic Engineering Commercial Law |
| ISBN |
1-283-69765-3
3-642-32841-5 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Preface -- Andreas Hübel: The Boundaries of Limits - Plant Biosciences -- Ulrich Storz: The Limits of Patentability - Stem Cells -- Aloys Hüttermann: The LImits of Patentability - Genes and Nucleic Acids -- About the Authors. |
| Record Nr. | UNINA-9910437854903321 |
Hübel Andreas
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| Berlin, Heidelberg : , : Springer Berlin Heidelberg : , : Imprint : Springer, , 2013 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Long Non Coding RNA Biology [[electronic resource] /] / edited by M.R.S. Rao
| Long Non Coding RNA Biology [[electronic resource] /] / edited by M.R.S. Rao |
| Edizione | [1st ed. 2017.] |
| Pubbl/distr/stampa | Singapore : , : Springer Singapore : , : Imprint : Springer, , 2017 |
| Descrizione fisica | 1 online resource (336 pages) : illustrations |
| Disciplina | 572.88 |
| Collana | Advances in Experimental Medicine and Biology |
| Soggetto topico |
Gene expression
Developmental biology Medical genetics Nucleic acids Gene Expression Developmental Biology Gene Function Nucleic Acid Chemistry |
| ISBN | 981-10-5203-4 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Chapter 1. Non coding RNA: History, Discovery and Classification of non coding RNA -- Chapter 2. Long non coding RNA: Genome organization and mechanism of action -- 3. Long non coding RNAs in Invertebrates: Drosophila -- Chapter 4. Long non coding RNAs in unicellular organisms: Yeast -- Chapter 5. Long non coding RNAs in Plants -- Chapter 6. Long non coding RNAs in mammalian development and disorders -- Chapter 7. Long non coding RNAs in Cancer and therapeutic potential -- Chapter 8. Long non coding RNAs in Stem cell and Differentiation -- Chapter 9. Long non coding RNAs in Brain development -- Chapter 10. Technological developments in lncRNA Biology. |
| Record Nr. | UNINA-9910253949403321 |
| Singapore : , : Springer Singapore : , : Imprint : Springer, , 2017 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Long Noncoding RNAs [[electronic resource] ] : Structures and Functions / / edited by Riki Kurokawa
| Long Noncoding RNAs [[electronic resource] ] : Structures and Functions / / edited by Riki Kurokawa |
| Edizione | [1st ed. 2015.] |
| Pubbl/distr/stampa | Tokyo : , : Springer Japan : , : Imprint : Springer, , 2015 |
| Descrizione fisica | 1 online resource (252 p.) |
| Disciplina | 570 |
| Soggetto topico |
Cell biology
Medical genetics Nucleic acids Cell Biology Gene Function Nucleic Acid Chemistry |
| ISBN | 4-431-55576-5 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Part I Bioinformatics and Other Methodologies for lncRNAs -- 1 Complexity of Mammalian Transcriptome Analyzed by RNA Deep Sequencing -- 2 Synthetic Strategies to Identify and Regulate Noncoding RNAs -- Part II Atomic and Molecular Structures of lncRNAs -- 3 Structure and Interaction with Protein of Noncoding RNA: A Case for an RNA Aptamer Against Prion Protein -- 4 Characterization of G-quadruplex DNA- and RNA-binding Protein -- Part III Molecular Functions of lncRNAs -- 5 Initiation of Transcription Generates Divergence of Long Noncoding RNAs -- 6 Beneath the Veil of Biological Complexity There Lies Long Noncoding RNA: Diverse Utilization of lncRNA in Yeast Genomes -- 7 Long Noncoding RNAs as Structural and Functional Components of Nuclear Bodies -- Part IV Biological Actions of lncRNAs -- 8 Long Noncoding RNA in Epigenetic Gene Regulation -- 9 Mechanisms of Long Noncoding Xist RNA-mediated Chromosome-wide Gene Silencing in X-chromosome Inactivation -- Part V Potential Outcomes for Clinical Medicine -- 10 Regulation of pRB and p53 Pathways by Long Noncoding RNAs, ANRIL, lincRNA-p21, lincRNA-RoR and PANDA -- 11 The Role of Androgen-regulated Long Noncoding RNAs in Prostate Cancer -- 12 Macrophage Activation as a Model System for Understanding Enhancer Transcription and eRNA Function -- 13 Long Noncoding RNA Functions as a Regulator for Steroid Hormone Receptors Related Breast and Prostate Cancers -- BM Index. |
| Record Nr. | UNINA-9910298269103321 |
| Tokyo : , : Springer Japan : , : Imprint : Springer, , 2015 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Lung Cancer and Autoimmune Disorders [[electronic resource] /] / edited by Mieczyslaw Pokorski
| Lung Cancer and Autoimmune Disorders [[electronic resource] /] / edited by Mieczyslaw Pokorski |
| Edizione | [1st ed. 2015.] |
| Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2015 |
| Descrizione fisica | 1 online resource (79 p.) |
| Disciplina | 616.978 |
| Collana | Neuroscience and Respiration |
| Soggetto topico |
Medicine
Cancer research Medical genetics Immunology Respiratory organs—Diseases Medical biochemistry Biomedicine, general Cancer Research Gene Function Pneumology/Respiratory System Medical Biochemistry |
| ISBN | 3-319-09752-0 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Polymorphisms of DNA repair genes and lung cancer in chromium exposure -- Circulating thrombospondin-2 and FGF-2 in patients with advanced non-small cell lung cancer: correlation with survival -- Mismatch repair gene polymorphisms and association with lung cancer development -- The potential of Wharton’s jelly derived mesenchymal stem cells in treating patients with cystic fibrosis -- Fatigue in sarcoidosis and exercise tolerance, dyspnea, and quality of life -- The rs1800471 polymorphism of TGFB1 gene, serum TGF-beta1 level and chronic kidney disease progression -- Immunological characteristics of children with Hashimoto’s autoimmune thyroiditis -- Endostatin and cathepsin V in bronchoalveolar lavage fluid of patients with pulmonary sarcoidosis -- Posturography in patients with rheumatoid arthritis and osteoarthritis. |
| Record Nr. | UNINA-9910298288503321 |
| Cham : , : Springer International Publishing : , : Imprint : Springer, , 2015 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Metabolomics: From Fundamentals to Clinical Applications [[electronic resource] /] / edited by Alessandra Sussulini
| Metabolomics: From Fundamentals to Clinical Applications [[electronic resource] /] / edited by Alessandra Sussulini |
| Edizione | [1st ed. 2017.] |
| Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2017 |
| Descrizione fisica | 1 online resource (X, 350 p. 56 illus., 54 illus. in color.) |
| Disciplina | 570.285 |
| Collana | Proteomics, Metabolomics, Interactomics and Systems Biology |
| Soggetto topico |
Metabolism
Gene therapy Medical genetics Metabolomics Gene Therapy Gene Function |
| ISBN | 3-319-47656-4 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Part I: Fundamentals and analytical methodologies in metabolomics -- 1. Metabolomics: definitions and significance in systems biology -- 2. Collection and preparation of clinical samples for metabolomics -- 3. NMR strategies in metabolomics -- 5. Strategies involving MS combined with chromatography in metabolomics -- 6.MS combined with capillary electrophoresis in metabolomics -- Part II: Statistical analysis and data interpretation -- 7. Data pretreatment: How to prepare a metabolomics dataset for statistical analysis? -- 8. Chemometrics in metabolomics -- Understanding metabolomics data: Metabolite identification and biological relevance -- Part III: Applications and future trends of metabolomics in clinical cases -- 9. Applications of metabolomics in cancer studies -- 10. Chronic diseases and lifestyle biomarkers identification by metabolomics -- 11. Metabolomics in neurological and psychiatric diseases -- 12. Metabolite profiling by MS imaging -- 13. Single cell metabolomics . |
| Record Nr. | UNINA-9910163043603321 |
| Cham : , : Springer International Publishing : , : Imprint : Springer, , 2017 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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MicroRNA in Cancer [[electronic resource] /] / edited by Suresh Alahari
| MicroRNA in Cancer [[electronic resource] /] / edited by Suresh Alahari |
| Autore | Alahari Suresh |
| Edizione | [1st ed. 2013.] |
| Pubbl/distr/stampa | Dordrecht : , : Springer Netherlands : , : Imprint : Springer, , 2013 |
| Descrizione fisica | 1 online resource (148 p.) |
| Disciplina | 616.994072 |
| Collana | Advances in Experimental Medicine and Biology |
| Soggetto topico |
Medicine
Gene expression Medical genetics Cancer research Cancer - Genetic aspects Non-coding RNA Genetic regulation MicroRNA Biomedicine, general Gene Expression Gene Function Cancer Research |
| ISBN |
1-283-93808-1
94-007-4655-5 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Preface; Contents; MicroRNAs and Other Non-Coding RNAs: Implications for Cancer Patients; 1 Introduction; 2 MiRNAs in Selected Malignancies; 2.1 Chronic Lymphocytic Leukemia; 2.2 Multiple Myeloma; 2.3 Cutaneous T-Cell Lymphoma; 2.4 Mantle Cell Lymphoma; 3 Soluble MiRNAs; 4 Other Non-coding RNAs; 4.1 MALAT-1; 4.2 HOTAIR; 4.3 H19; 4.4 XIST; 4.5 SnaR Family Members; 4.6 Other Transcribed Ultraconserved Regions; 5 Implications for the Treatment of Cancer; References; Function of miRNAs in Tumor Cell Proliferation; 1 Introduction; 2 Aberrant miRNA Expression in Cancer
3 miRNA Regulation of Tumor Cell Division3.1 Cell Division Cycle; 3.2 miRNAs Inhibiting Tumor Cell Proliferation; 3.2.1 miR-15a and miR-16-1; 3.2.2 miR-17/20; 3.2.3 miR-221/222; 3.2.4 Let-7; 3.2.5 miR-29; 3.2.6 miR-34, miR-192 and miR-215; 3.3 miRNAs Enhancing Tumor Cell Proliferation; 3.3.1 miR-21; 3.3.2 miR-27a; 3.3.3 miR-155; 4 miRNA Regulation of Cancer Stem Cells; 5 miRNA Regulation of Tumor Microenvironment and Cancer Metastasis; 6 Therapeutic Application of miRNA in Cancer; 6.1 Restoring the Expression of Tumor Suppressor miRNAs; 6.2 Blocking the Function of Oncogenic miRNAs ReferencesMicroRNAs in Cancer Stem Cells; 1 The Cancer Stem Cell Hypothesis; 2 Links between EMT and the CSC phenotype; 3 microRNAs in CSCs; 4 The cell of origin for Cancer Stem Cells; 5 microRNAs in Normal Stem Cells and Development; 6 Regulation of CSC-Associated microRNAs; 7 Conclusions; References; MicroRNAs in the Pathogenesis of Viral Infections and Cancer; 1 Introduction; 2 Viral miRNAs; 3 Viral miRNAs Targeting Viral Messages; 4 Viral miRNAs that Regulate Host Genes; 5 Cancer and miRNAs; 6 Conclusions; References; Oncogenic microRNAs in Cancer; 1 Introduction 2 Role of Oncogenic microRNAs in Normal Cellular Processes3 Oncogenic microRNAs vs Tumor Suppressive microRNAs; 4 Oncogenic microRNA-Mediated Tumor Growth; 5 Oncogenic microRNA-Mediated Invasion and Metastasis; 6 Cell Type Specific Effect of microRNAs; 7 Oncogenic microRNA-Mediated Resistance to Chemotherapy and Radiation Therapy; 8 Oncogenic microRNAs as a Biomarker for Cancer Diagnosis and Prognosis, and as Therapeutic Targets; 9 Summary; References; Regulation of Metastasis by miRNAs; 1 MiRNAs: The Basics; 1.1 Discovery; 1.2 Biogenesis; 1.3 Mechanism of miRNA Gene Regulation 2 MicroRNAs and Metastasis2.1 Function of Specific miRNAs in EMT; 2.2 miRNAs Drive the Cancer Metastasis; 2.2.1 miR-21; 2.2.2 miR-10b; 2.2.3 miR-182, miR-183, miR-380-5p and miR-211; 2.2.4 Others (miR-1, miR-126, let-7, miR-29c and miR-214); 2.3 miRNAs Suppress Tumor Metastasis; 2.3.1 miR-335, miR-206 and miR-126; 2.3.2 miR-31; 2.3.3 miR-146a and miR-146b; 2.3.4 miR-205; 2.3.5 Others (miR-29b, miR-198, miR-34a, let-7f); 3 Conclusion and Future Perspective; References; MicroRNA in Leukemias; 1 Introduction; 1.1 MicroRNAs in ALL; 1.1.1 MicroRNA Expression Profiling ; 1.1.2 MiRNA Regulation, Cellular Function and Prognostic Significance |
| Record Nr. | UNINA-9910437622303321 |
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Alahari Suresh
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| Dordrecht : , : Springer Netherlands : , : Imprint : Springer, , 2013 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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MicroRNAs: Key Regulators of Oncogenesis [[electronic resource] /] / edited by Sadegh Babashah
| MicroRNAs: Key Regulators of Oncogenesis [[electronic resource] /] / edited by Sadegh Babashah |
| Edizione | [1st ed. 2014.] |
| Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2014 |
| Descrizione fisica | 1 online resource (449 p.) |
| Disciplina | 616.994071 |
| Soggetto topico |
Cancer research
Human genetics Gene expression Medical genetics Molecular biology Drug resistance Cancer Research Human Genetics Gene Expression Gene Function Molecular Medicine Drug Resistance |
| ISBN | 3-319-03725-0 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Preface -- Part I MicroRNAs: biology and implications in cancer -- MicroRNAs and cancer: an overview -- Epigenetics and microRNA in cancer -- MicroRNA, diet and cancer chemoprevention -- MicroRNAs and energy metabolism in cancer cells -- MicroRNAs and solid tumors -- MicroRNAs and blood cancers -- MicroRNAs and oncogenic human viruses -- MicroRNAs linking cancer and inflammation: focus on liver cancer -- MicroRNAs and regulatory pathways in tumorigenesis -- MicroRNA-modulated apoptotic and autophagic signaling networks in cancer -- MicroRNAs and cancer drug resistance and drug sensitivity -- The biological roles of microRNAs in cancer stem cells -- Part II MicroRNAs and their clinical implications -- MicroRNAs and clinical implications in cancer -- MicroRNA expression profiling and its clinical impact in breast cancer -- MicroRNAs and their clinical impact on resistance to anticancer treatment -- Nanocarriers and microRNA-based scenarios for cancer therapy -- Challenges and strategies for pulmonary delivery of microRNA-based therapeutics -- Abbreviations -- Index. |
| Record Nr. | UNINA-9910298300703321 |
| Cham : , : Springer International Publishing : , : Imprint : Springer, , 2014 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Multiple Sclerosis Immunology [[electronic resource] ] : A Foundation for Current and Future Treatments / / edited by Takashi Yamamura, Bruno Gran
| Multiple Sclerosis Immunology [[electronic resource] ] : A Foundation for Current and Future Treatments / / edited by Takashi Yamamura, Bruno Gran |
| Edizione | [1st ed. 2013.] |
| Pubbl/distr/stampa | New York, NY : , : Springer New York : , : Imprint : Springer, , 2013 |
| Descrizione fisica | 1 online resource (468 p.) |
| Disciplina | 616.834 |
| Soggetto topico |
Immunology
Medical genetics Molecular biology Gene Function Molecular Medicine |
| ISBN | 1-4614-7953-3 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Th17 cells in autoimmune inflammation and demyelination in the central nervous system -- Regulatory T cells in MS -- T-bet: A critical regulator of encephalitogenic T Cells -- Antigen-presenting cells in the Central Nervous System -- The role of B cells in multiple sclerosis -- Diet, gut flora and multiple sclerosis: current research and future perspectives -- GM-CSF in autoimmune inflammation of the central nervous system -- The role of Toll-like receptors in multiple sclerosis and experimental autoimmune encephalomyelitis -- Macrophages and microglia in experimental autoimmune encephalomyelitis and multiple sclerosis -- Genetics of multiple sclerosis -- Gene expression profiling and pathway analysis for identification of molecular targets in MS -- Systems biology for the study of multiple sclerosis -- Checkpoints in the development of pathogenic and regulatory T cells in Experimental Autoimmune Encephalomyelitis—a basis for current future interventions in MS -- Modeling MS in non-human primates -- A novel concept of treatment in MS: targeting both oligodendrocyte death and inflammatory processes by inhibiting poly (ADP-Ribose) polymerase -- Association of MS with other autoimmune diseases -- Current and future treatments of Multiple Sclerosis -- Targeting CD52 for the treatment of Multiple Sclerosis -- Haematopoietic stem cells for the treatment of MS -- Mesenchymal stem cells for the treatment of Multiple Sclerosis. |
| Record Nr. | UNINA-9910437851803321 |
| New York, NY : , : Springer New York : , : Imprint : Springer, , 2013 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Soggetto topico
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Gene Function
(60)
- Medical genetics (60)
- Gene Expression (14)
- Gene expression (14)
- Proteins (12)