Modern drug research : paths to better and safer drugs / edited by Yvonne Connolly Martin, Eberhard Kutter, Volkhard Austel |
Pubbl/distr/stampa | New York : M. Dekker, copyr. 1989 |
Descrizione fisica | XIV, 507 p. ; 23 cm |
Disciplina | 615.1 |
Collana | Medicinal research |
Soggetto topico | Farmacologia |
ISBN | 0-8247-7902-9 |
Formato | Materiale a stampa ![]() |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Record Nr. | UNISA-990001104130203316 |
New York : M. Dekker, copyr. 1989 | ||
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Lo trovi qui: Univ. di Salerno | ||
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Modern phamaceutics / edited by Gilbert S. Banker, Christopher T. Rhodes |
Edizione | [4. ed. revised and expanded] |
Pubbl/distr/stampa | New York etc.] : M. Dekker |
Descrizione fisica | XI, 838 p. ; 30 cm |
Disciplina | 615.1 |
Collana | Drugs and the pharmaceutical sciences |
Soggetto topico | Farmacologia |
ISBN | 0-8247-0674-9 |
Formato | Materiale a stampa ![]() |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Record Nr. | UNISA-990001517390203316 |
New York etc.] : M. Dekker | ||
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Lo trovi qui: Univ. di Salerno | ||
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Molecular Targeted Radiosensitizers [[electronic resource] ] : Opportunities and Challenges / / edited by Henning Willers, Iris Eke |
Edizione | [1st ed. 2020.] |
Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Humana, , 2020 |
Descrizione fisica | 1 online resource (XI, 364 p. 42 illus., 38 illus. in color.) |
Disciplina | 616.9940642 |
Collana | Cancer Drug Discovery and Development |
Soggetto topico |
Cancer research
Radiotherapy Pharmacology Cancer Research Pharmacology/Toxicology Farmacologia Investigació farmacèutica Oncologia Radiologia mèdica |
Soggetto genere / forma | Llibres electrònics |
ISBN | 3-030-49701-1 |
Formato | Materiale a stampa ![]() |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto | Introduction to Molecular Targeted Radiosensitizers: Opportunities and Challenges -- Translating Targeted Radiosensitizers into the Clinic -- Cartography of the Radiogenome of Human Cancers -- Mechanisms and Markers of Clinical Radioresistance -- Preclinical Strategies for Testing of Targeted Radiosensitizers -- 3D Radiation Biology for Identifying Radiosensitizers -- Preclinical in vivo evaluation of novel radiosensitizers by local tumor control experiments -- Genetically Engineered Mouse Models for Studying Radiation Biology and Radiosensitizers -- Targeting the DNA Damage Response for Radiosensitization -- Targeting Tumor Metabolism to Overcome Radioresistance.-Targeting Tumor Hypoxia -- Normalizing the Tumor Microenvironment for Radiosensitization -- Radiosensitizers in the Era of Immuno-Oncology -- Index. |
Record Nr. | UNINA-9910416133603321 |
Cham : , : Springer International Publishing : , : Imprint : Humana, , 2020 | ||
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Lo trovi qui: Univ. Federico II | ||
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Nanoformulations in Human Health [[electronic resource] ] : Challenges and Approaches / / edited by Sushama Talegaonkar, Mahendra Rai |
Edizione | [1st ed. 2020.] |
Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2020 |
Descrizione fisica | 1 online resource (XVIII, 548 p. 106 illus., 91 illus. in color.) |
Disciplina | 615.6 |
Soggetto topico |
Pharmacology
Pharmacotherapy Pharmacology/Toxicology Nanotecnologia Farmacologia Salut |
Soggetto genere / forma | Llibres electrònics |
ISBN | 3-030-41858-8 |
Formato | Materiale a stampa ![]() |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto | Nano-technological Platforms and Manipulations for the Emerging Ocular Manifestations -- Phytonanomedicines as Topical Alternatives for the Treatment of Skin Cancer -- Nano-sized Labile and Particulate Ingredients in Topical Formulations: A Strategic Approach Against Photoageing and Photocarcinogenisis -- Application of Biocompatible Nanocarriers in Glaucoma: Challenges and Advances -- Nano-carriers for Natural Therapeutics in the Management of Neuropathic Pain -- Advances in the Delivery of Therapeutic Peptides -- Nanoformulations and Their Role in Colon Targeting -- Theranostic Nanoformulations: Merging Diagnostics and Therapeutics -- The Role of Nanoformulations in Nose-To-Brain Drug Delivery -- Cubic Lyotropic Liquid Crystalline Nanostructures: A Versatile Platform for Delivery -- Preformulation Challenges: The Concept Behind the Selection, Design, and Preparation of Nanoformulations -- Nanoethosomes for Topical Fungal Therapeutics -- Comparison of Therapeutic Efficiency of Nanoformulations of Curcumin vs. Tetrahydrocurcumin in Various Disorders -- Nanomedicinal Approaches of Phytotherapeutics to Treat Alzheimers Disease -- Nanoparticulate Approaches to Exploit the Pathophysiology of Rheumatoid and Osteoarthritis -- Emerging Nanotechnology in Chronic Respiratory Diseases -- Conventional and Non-conventional Approaches of Site-specific Targeting of Therapeutics in Some Infectious Diseases and Metabolic Disorders -- Nanoformulations in Human Health Conditions: The Paradigm Shift -- Magnetic Nanoparticles Nanoformulation for Alternative Therapy of Cancer by Super-paramagnetic Hyperthermia -- Nano-weapons Against Tuberculosis -- Drug-Excipient Interactions in Nanoformulations with Special Focus on Impurity Control per ICH guidelines. |
Record Nr. | UNINA-9910416103503321 |
Cham : , : Springer International Publishing : , : Imprint : Springer, , 2020 | ||
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Lo trovi qui: Univ. Federico II | ||
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Network pharmacology / / edited by Shao Li |
Pubbl/distr/stampa | Singapore : , : Springer, , [2021] |
Descrizione fisica | 1 online resource (480 pages) |
Disciplina | 769.563 |
Soggetto topico |
Pharmacy
Bioinformatics Farmacologia Bioinformàtica |
Soggetto genere / forma | Llibres electrònics |
ISBN | 981-16-0753-2 |
Formato | Materiale a stampa ![]() |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto |
Intro -- Foreword -- Foreword -- Foreword -- Preface -- Contents -- Chapter 1: ``Network Target´´ Theory and Network Pharmacology -- 1.1 Network Pharmacology: Next Generation Medicine Research Mode -- 1.2 Key Role of TCM in the Origin and Development of Network Pharmacology -- 1.2.1 Original Method of Network Target Analysis -- 1.2.2 Common Methods of Network Target Analysis -- 1.3 Core Theory of Network Pharmacology: Network Target -- 1.3.1 Proposal and Development of Network Target Theory -- 1.3.2 The Concept of Network Target -- 1.4 Overview of Network Pharmacology Research Methods and Characteristics -- 1.4.1 Characteristics of ``Single Target-Partial Confrontation´´ Research Mode -- 1.4.2 Characteristics of ``Network Target-System Regulation´´ Research Mode -- 1.4.3 Typical Scenarios of Network Pharmacology Analysis -- 1.4.4 Characteristics, Advantages, Challenges, and Developmental Direction of Network Pharmacology Research -- References -- Chapter 2: Application of Network Pharmacology Based on Artificial Intelligence Algorithms in Drug Development -- 2.1 Introduction to Artificial Intelligence Methods in Network Pharmacology -- 2.1.1 Introduction to Artificial Intelligence Algorithms -- 2.1.2 Performance Evaluation Method for Artificial Intelligence Algorithms -- 2.1.3 Applications of Artificial Intelligence -- 2.1.4 Frontiers and Prospects of Artificial Intelligence -- 2.2 Application of Artificial Intelligence in Network Pharmacology Research -- 2.2.1 Prediction and Discovery of Drug Targets -- 2.2.2 Study on the Drug Property Mechanism -- 2.2.3 Discovery of New Drug Uses -- 2.2.4 Traditional Chinese Medicine and Its Therapeutic Theory -- 2.3 Application of Artificial Intelligence -- References -- Chapter 3: Common Network Pharmacology Databases -- 3.1 TCM Databases Commonly Used in Network Pharmacology.
3.1.1 ETCM: Encyclopedia of Traditional Chinese Medicine -- 3.1.1.1 Data Structure -- 3.1.1.2 Function Introduction -- 3.1.1.3 Characteristics -- 3.1.2 SymMap: Integrated TCM Database Focusing on the Association of Syndromes -- 3.1.2.1 Data Structure -- 3.1.2.2 Function Introduction -- 3.1.2.3 Characteristics -- 3.1.3 BATMAN-TCM: Bioinformatics Analysis Platform for the Molecular Mechanism of Traditional Chinese Medicine -- 3.1.3.1 Data Structure -- 3.1.3.2 Function Introduction -- 3.1.3.3 Characteristics -- 3.1.4 TCMID: TCM Integrated Database for Molecular Mechanism Analysis of TCM -- 3.1.4.1 Data Structure -- 3.1.4.2 Function Introduction -- 3.1.4.3 Characteristics -- 3.1.5 Other TCM Databases -- 3.2 Biological Databases Commonly Used in Network Pharmacology -- 3.2.1 Online Mendelian Inheritance in Man-OMIM -- 3.2.1.1 Database Content and Its Application in Network Pharmacology Research -- 3.2.1.2 Data Structure -- 3.2.1.3 Function Introduction -- 3.2.1.4 Characteristics -- 3.2.2 Human Phenotypic Ontology Database-HPO -- 3.2.2.1 Database Content and Its Application in Network Pharmacology Research -- 3.2.2.2 Data Structure -- 3.2.2.3 Function Introduction -- 3.2.2.4 Characteristics and Deficiencies -- 3.2.3 Disease Gene Association Database-DisGeNET -- 3.2.3.1 Data Structure -- 3.2.3.2 Function Introduction -- 3.2.3.3 Characteristics -- 3.2.4 Disease Information Data-MalaCards -- 3.2.4.1 Introduction and Usage of the Database -- 3.2.4.2 Characteristics -- 3.3 Related Databases of Commonly Used Gene Targets in Network Pharmacology -- 3.3.1 Therapeutic Target Database-TTD -- 3.3.1.1 Data Structure -- 3.3.1.2 Function Introduction -- 3.3.1.3 Characteristics -- 3.3.2 Protein Data Bank-PDB -- 3.3.2.1 Data Structure -- 3.3.2.2 Function Introduction -- 3.3.2.3 Characteristics and Deficiencies -- 3.3.3 Gene Information Database-GeneCards. 3.3.3.1 Data Structure -- 3.3.3.2 Applications/Functions in the Field of Molecular Biology -- 3.3.3.3 Characteristics and Deficiencies -- 3.3.4 Kyoto Encyclopedia of Genes and Genomes-KEGG -- 3.3.4.1 Data Structure -- 3.3.4.2 Function Introduction -- 3.3.4.3 Characteristics and Deficiencies -- 3.4 Protein Interaction Databases Commonly Used in Network Pharmacology -- 3.4.1 Biological Universal Interaction Database-BioGRID -- 3.4.1.1 Data Structure -- 3.4.1.2 Function Introduction -- 3.4.1.3 Characteristics -- 3.4.2 Database of Interacting Proteins-DIP -- 3.4.2.1 Data Structure -- 3.4.2.2 Function Introduction -- 3.4.2.3 Characteristics -- 3.4.3 Molecular Interaction Database-IntAct -- 3.4.3.1 Data Structure -- 3.4.3.2 Function Introduction -- 3.4.4 Database of Gene/Protein Interactions-STRING -- 3.4.4.1 Data Structure -- 3.4.4.2 Function Introduction -- 3.4.4.3 Characteristics -- References -- Chapter 4: Common Network Pharmacology Software -- 4.1 Software Functional Framework and Classification of Network Pharmacology -- 4.1.1 Overall Software Functional Requirements -- 4.1.2 Software Functional Framework and Classification of Network Pharmacology -- 4.2 Online Software Commonly Used in Network Pharmacology -- 4.2.1 Online Software for Drug-Target Prediction -- 4.2.2 Online Software for Drug Indication Analysis -- 4.2.3 Online Software for Gene Function Enrichment Analysis -- 4.2.4 Online Software for Constructing Protein Interaction Network -- 4.3 Software Based on Graphical Interface Operation -- 4.3.1 Differential Gene Enrichment Analysis Software -- 4.3.1.1 Software Installation -- 4.3.1.2 Data Preparation and Import -- 4.3.1.3 Setting Parameters and Running the Software -- 4.3.1.4 View Results -- 4.3.2 Network Analysis Software -- 4.3.2.1 Cytoscape -- Basic Use -- Exemplary Functional Components -- 4.3.2.2 Gephi Visualization Software. 4.3.2.3 Pajek Complex Network Visualization Software -- 4.4 Toolkit Based on Programming Languages -- 4.4.1 NetworkX -- 4.4.2 igraph -- References -- Chapter 5: Case Study of Network Pharmacology and Modernization of Traditional Chinese Medicine -- 5.1 Guide to this Chapter -- 5.2 Study of Network Pharmacology and TCM syndromes -- 5.2.1 Case Analysis of Network Pharmacology Research on Cold and Hot Syndromes and Corresponding Prescriptions -- 5.2.1.1 Research Objective -- 5.2.1.2 Data Source -- 5.2.1.3 Network Construction and Visualization -- 5.2.1.4 Analysis Index and Algorithm -- 5.2.1.5 Experimental Verification -- 5.2.1.6 Conclusion -- 5.2.2 Case Study and Analysis of ``Same Disease with Varying Syndromes´´ in Hepatic Fibrosis Caused by Chronic Hepatitis B -- 5.2.2.1 Research Objective -- 5.2.2.2 Data Source -- 5.2.2.3 Network Construction and Visualization -- 5.2.2.4 Analysis Index and Algorithm -- Network Analysis -- Analysis of Clinical Experimental Data -- 5.2.2.5 Main Conclusion -- 5.3 Case Study of Network Pharmacology and TCM Prescriptions -- 5.3.1 Research and Analysis of DMIM: An Interactive Information Model Based on the Spacing of TCM Compound Prescriptions -- 5.3.1.1 Research Objective -- 5.3.1.2 Data Source -- DMIM Analysis-Related Data -- Related LWDH Data -- 5.3.1.3 Network Construction and Visualization -- 5.3.1.4 Analysis Index and Algorithm -- 1) Mathematical Expression of TCM Prescriptions -- Mutual Information Entropy -- Spacing of Chinese Medicine Between Prescriptions -- DMIM Scoring System -- 5.3.1.5 Experimental Verification -- The Angiogenesis Activity of Chinese Medicines Screened by DMIM System was Evaluated Through In Vitro Experiments -- Experiment of Traditional Chinese Drug Pairs Predicted by DMIM -- 5.3.1.6 Main Conclusion -- 5.3.2 Network Pharmacology Analysis of Liuwei Dihuang Prescription. 5.3.2.1 Research Objective -- 5.3.2.2 Data Source -- 5.3.2.3 Network Construction and Visualization -- 5.3.2.4 Experimental Verification -- 5.3.2.5 Main Conclusion -- 5.4 Research Case on Network Pharmacology and TCM Formulation -- 5.4.1 Multi-component Synergy Recognition Method Based on Network Target -- 5.4.1.1 Research Objective -- 5.4.1.2 Data Source -- 5.4.1.3 Network Construction and Visualization -- 5.4.1.4 Analysis Index and Algorithm -- 5.4.1.5 Experimental Verification -- 5.4.1.6 Main Conclusion -- 5.4.2 Study on the Multi-target Mechanism of Artemisinin Against Plasmodium Falciparum -- 5.4.2.1 Research Objective -- 5.4.2.2 Data Source -- 5.4.2.3 Network Construction and Visualization -- 5.4.2.4 Analysis Index and Algorithm -- 5.4.2.5 Experimental Verification -- 5.4.2.6 Main Conclusion -- 5.5 Network Pharmacology and Ethnic Medicine Research Cases -- 5.5.1 Comparative Study and Analysis on Chemical Components and Pharmacological Effects of Three Species of Siegesbeckia -- 5.5.1.1 Research Objective -- 5.5.1.2 Data Source -- 5.5.1.3 Network Construction and Visualization -- 5.5.1.4 Analysis Index and Algorithm -- Compound similarity algorithm -- Network Analysis -- 5.5.1.5 Experimental Verification -- 5.5.1.6 Main Conclusion -- 5.5.2 Study and Analysis on the Mechanism of Hedyotis Diffusa Willd against Non-small Cell Lung Cancer -- 5.5.2.1 Research Objective -- 5.5.2.2 Data Source -- 5.5.2.3 Network Construction and Visualization -- 5.5.2.4 Analysis Index and Algorithm -- 5.5.2.5 Experimental Verification -- Animal Experiments -- Cell Experiments -- 5.5.2.6 Main Conclusion -- 5.6 Network Pharmacology and International Traditional Medicine Research Cases -- 5.6.1 Study and Analysis on Anti-cancer Activity of Calophyllum Brasiliense -- 5.6.1.1 Research Objective -- 5.6.1.2 Data Source -- 5.6.1.3 Network Construction and Visualization. 5.6.1.4 Analysis Index and Algorithm. |
Record Nr. | UNINA-9910502975503321 |
Singapore : , : Springer, , [2021] | ||
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Lo trovi qui: Univ. Federico II | ||
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New taegets for the treatment of hypertension and associated diseases / edited by William B. Campbell , John D. Imig ; series editor S. J. Enna |
Pubbl/distr/stampa | Cambridge, MA, : Elsevier Academic Press, 2022 |
Descrizione fisica | X, 409 p. : ill. ; 24 cm |
Disciplina | 615 |
Collana | Advances in Pharmacology |
Soggetto topico | Farmacologia |
ISBN | 978-0-323-91087-3 |
Formato | Materiale a stampa ![]() |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Record Nr. | UNISA-996577572103316 |
Cambridge, MA, : Elsevier Academic Press, 2022 | ||
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Lo trovi qui: Univ. di Salerno | ||
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Nucleic acid targeted drug desig / edited by C.L. Propst, Thomas J. Perun |
Pubbl/distr/stampa | New York [etc.] : Dekker, copyr. 1992 |
Descrizione fisica | XIII, 619 : ill. ; 24 cm |
Disciplina | 615.19 |
Soggetto topico |
Farmacologia
Acido desossiribonucleico |
ISBN | 0-8427-8662-9 |
Formato | Materiale a stampa ![]() |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Record Nr. | UNISA-990001187880203316 |
New York [etc.] : Dekker, copyr. 1992 | ||
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Lo trovi qui: Univ. di Salerno | ||
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Opinion & evidence : drug treatment / editor: Gordon Mallarkey |
Pubbl/distr/stampa | Auckland [etc.] : Adis intenational, copyr. 1999 |
Descrizione fisica | IV, 205 p. ; 22 cm |
Disciplina | 615.1 |
Soggetto topico | Farmacologia |
ISBN | 0-86471-044-5 |
Formato | Materiale a stampa ![]() |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Record Nr. | UNISA-990000370450203316 |
Auckland [etc.] : Adis intenational, copyr. 1999 | ||
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Lo trovi qui: Univ. di Salerno | ||
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Opinion & evidence : drug treatment / editor: Gordon Mallarkey |
Pubbl/distr/stampa | Auckland [etc.] : Adis intenational, copyr. 1999 |
Descrizione fisica | IV, 205 p. ; 22 cm |
Disciplina | 615.1 |
Soggetto topico | Farmacologia |
ISBN | 0-86471-051-8 |
Formato | Materiale a stampa ![]() |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Record Nr. | UNISA-990000370410203316 |
Auckland [etc.] : Adis intenational, copyr. 1999 | ||
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Lo trovi qui: Univ. di Salerno | ||
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Opinion & evidence : drug safety / editor: Ralph Edwards |
Pubbl/distr/stampa | Auckland [etc.] : Adis intenational, copyr. 1998 |
Descrizione fisica | 1 v. (paginazione varia) ; 22 cm |
Disciplina | 615.1 |
Soggetto topico | Farmacologia |
ISBN | 0-86471-044-5 |
Formato | Materiale a stampa ![]() |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Record Nr. | UNISA-990000370500203316 |
Auckland [etc.] : Adis intenational, copyr. 1998 | ||
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Lo trovi qui: Univ. di Salerno | ||
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