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Drug Discovery and Design Using Natural Products / / Jorddy Neves Cruz
| Drug Discovery and Design Using Natural Products / / Jorddy Neves Cruz |
| Autore | Cruz Jorddy Neves |
| Edizione | [First edition.] |
| Pubbl/distr/stampa | Cham, Switzerland : , : Springer Nature Switzerland AG, , [2023] |
| Descrizione fisica | 1 online resource (540 pages) |
| Disciplina | 615.19 |
| Soggetto topico |
Drugs - Design
Natural products |
| ISBN | 3-031-35205-X |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Section 1: Genesis of research projects that use natural products to design new drugs -- Chapter title: Drug development projects guided by ethnobotany and ethnopharmacology studies -- Chapter content: In this chapter, the authors will be encouraged to demonstrate how traditional knowledge of local populations can provide vital information for developing projects that seek to validate the pharmacological use of plants scientifically -- Correspondence author: Neelam S Sangwan, School of Interdisciplinary and Applied Sciences, Central University of Haryana, Haryana, India, Email: drneelamsangwan@gmail.com -- Section 2: Initial processes for identifying and extracting compounds; Isolation and identifying these structures -- Chapter title: Natural Deep Eutectic Solvents (NADES) for Extraction and Isolation of Biological Active Natural Products -- Chapter content: The choice and use of solvents are crucial steps in extracting and dissolving natural or synthetic organic compounds. Many of these organic solvents are carcinogenic and harmful to human health. Therefore, there is great interest in studies to develop new green solvents to replace traditionally used solvents. These green solvents have the general characteristics of not being harmful to the environment and having good health and safety. At the forefront of green solvents, natural deep eutectic solvents (NADES) deserve to be highlighted. Nades are products of the interactions of organic acids and sugars through hydrogen bonds and van der Waals-type interactions, offering advantages such as low toxicity, biodegradability, sustainability, and simple preparation. This chapter will address the use of these compounds for extraction and isolation projects of natural products -- Correspondence author: Christophe Hano, Eure et Loir Campus, Université d'Orléans,Chartres, France, Email: hano@univ-orleans.fr -- Chapter title: Secondary metabolites from marine microalgae and their potential for drug development -- Chapter content: There is a great diversity of organisms living in an aquatic environment or fully immersed in it. These microorganisms have a great potential for the production of biomolecules, as well as organisms of plant origin. These marine organisms produce various compounds through their secondary metabolism to protect or attack aggressors and prey. The chemical nature of these compounds is very diverse, and they can be explored as potential molecules for therapeutic use. This chapter will address this topic to provide readers with an overview of drug development based on secondary metabolites of marine microalgae.-Correspondence author: Giovanna Romano, Section Integrated Marine Ecology, Stazione Zoologica Anton Dohrn, Napoli, Italy, Email: giovanna.romano@szn.it -- Chapter title: Chromatographic methods for separation and identification of bioactive compounds -- Chapter content: Chromatographic methods have been used for qualitative and quantitative analysis of plant materials in extracts, essential oils, fixed oils, and isolated molecules. These methods have been of great support for projects investigating the biological properties of these processed plant materials, as they support the interpretation of the biological potential explored from understanding the presence of chemical structures in these processed plant materials. Here, the authors of the chapter will approach, but will not be restricted to, the report of advantages and disadvantages in the use of this equipment and applications of this equipment in research projects of new drugs and drug development -- Correspondence author: Renan Campos, Laboratory of Systematic Investigation in Biotechnology and Molecular Biodiversity, Federal University of Pará, Belém, Brazil, Email: renan.c.silva@outlook.com -- Chapter Title: Methods of Dereplication -- Correspondence author: Dereplication is a technique used to identify known molecules that have been reported in the literature; as compounds are already known, several of their biological properties have already been investigated and reported. Using this technique allows researchers to save time, as already known compounds will not be isolated and identified, thus allowing researchers more time to focus their energies on discovering a new bioactive compound. Therefore, this chapter's central theme will be the use of dereplication techniques and their impact on advances in the frontier of knowledge about novel compounds of natural origin -- Correspondence author: Ignacio Perez-Victoria, Fundación MEDINA, Centro de Excelencia en Investigación de Medicamentos Innovadores en Andalucía, Parque Tecnológico de Ciencias de la Salud, Avda. del Conocimiento, Granada, Spain, Email: ignacio.perez-victoria@medinaandalucia.es -- Section 3: Screening of compounds using molecular modeling approaches; Optimization of natural compounds using in silico methods -- Chapter title: High-throughput virtual screening (HTVS) methods of compounds of natural origin -- Correspondence author: This method is widely used in initial drug discovery projects, being of great importance to investigating the ability of various compounds to interact with a molecular target. Here the authors will discuss ligand-based and structure-based methods for screening compounds -- Correspondence author: Jean-Yves Trosset, Bio-Information Research Laboratory: Numerical Biology & Chem-Informatics, Sup'Biotech Paris, França, Email: jean-yves.trosset@supbiotech.fr -- Chapter title: In silico optimization processes of natural compounds; Chapter content: The chapter will generally address molecular modeling methodologies capable of modifying and/or evaluating molecular modifications in natural compounds. Methods capable of investigating ligand-receptor interaction will also be discussed. Discussions about molecular docking methods, SAR, QSAR, molecular dynamics simulation, and free energy methods will be addressed but not restricted. Correspondence author: Cleydson Breno, Laboratory of Modeling and Computational Chemistry, Department of Biological and Health Sciences, Federal University of Amapá, Macapá, Brazil, Email: breno@unifap.br -- Section 4: Synthesis of compounds of natural origin; Synthesis of new compounds from natural molecules -- Chapter title: Recent advances in the use of Diversity-oriented synthesis (DOS) based on libraries of natural compounds -- Chapter contents: Fragment-based drug discovery (FBDD) project can be aided by diversity-oriented synthesis. Therefore, in this chapter, the authors will be free to discuss DOS designs that use natural fragments or fragments close to natural structures because some scaffolds that serve as inspiration are structurally comparable to molecules of natural origin. Therefore, the authors will be free to discuss the contributions and the main aspects of projects related to FBDD and DOS -- Correspondence author: Francisco Ramon Sarabia Garcia, Department of Organic Chemistry, Faculty of Sciences, University of Malaga, Campus de Teatinos, Malaga, Spain, Email: frsarabia@uma.es -- Chapter title: Eseential oil derived monoterpenes in drug development -- Chapter content: Plant organisms are a great source of bioactive compounds. These molecules are present in several plant organs and can be organized in the form of fixed and volatile compounds. Fixed compounds are extracted and can be isolated, while volatile compounds are obtained from essential oil. Terpenoids are volatile compounds in several plant species with broad economic and medicinal value. The properties of these compounds are investigated through biological evaluations of essential oil rich in monoterpenes; pharmacological investigations of isolated monoterpenes are also carried out. This chapter will discuss how monoterpene-rich essential oils are pharmacologically investigated and evaluate the therapeutic results of isolated monoterpenes -- Correspondence author: Varughese George, Amity Institute of Phytochemistry and Phytomedicine, Kerala, India, Email: georgedrv@yahoo.co.in -- Section 5: Identification of molecular targets of natural molecules -- Chapter title: Trends topics on methods used to elucidate molecular targets of biomolecules -- Chapter content: After a compound has its biological property evaluated, the discovery of its molecular target becomes a vital point of the research project. This challenge needs to be faced with the use of techniques that are fast and economically viable for research groups. Thus, the primary methods capable of elucidating the molecular target of bioactive compounds will be reported here, as well as their advantages and disadvantages in drug discovery projects -- Correspondence author: Cibele dos Santos Borges, Department of Bioscience, Federal Rural University of Semi-Arid Region, Mossoró, Rio Grande do Norte, Brazil, Email: cibele.borges@ufersa.edu.br -- Section 6: Successful new drug projects inspired by natural products -- Chapter title Molecular mechanisms of natural products regulating metabolism and health.-Chapter content: Many diseases are caused by disorders in our metabolisms, such as diabetes, obesity, and dyslipidemias. Some natural compounds can modulate the organism to improve the response to these disorders. These natural compounds, which can be flavonoids, and terpenoids, among others, have a variety of actions. In this chapter, the regulation of metabolic disorders will be addressed, in addition to investigating the function and potential mechanisms of action of certain natural products -- Correspondence author: Ivan Torre Villalvazo, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Departamento de Fisiología de la Nutrición, Mexico, Email: ivan.torrev@incmnsz.mx -- Chapter title: Patent process for natural compounds and their analogs -- Contents of the chapter: Patent processes for natural products are problematic, as the intellectual appropriation of something present in nature is an obstac. |
| Record Nr. | UNINA-9910742498803321 |
Cruz Jorddy Neves
|
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| Cham, Switzerland : , : Springer Nature Switzerland AG, , [2023] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Drug discovery handbook [[electronic resource] /] / edited by Shayne Cox Gad
| Drug discovery handbook [[electronic resource] /] / edited by Shayne Cox Gad |
| Pubbl/distr/stampa | Hoboken, N.J., : Wiley-Interscience, c2005 |
| Descrizione fisica | 1 online resource (1493 p.) |
| Disciplina | 615/.19 |
| Altri autori (Persone) | GadShayne C. <1948-> |
| Collana | Pharmaceutical Development Series |
| Soggetto topico |
Drugs - Research
Drug development Drugs - Design Pharmaceutical chemistry |
| ISBN |
1-280-27707-6
9786610277070 0-470-30589-4 0-471-72877-2 0-471-72878-0 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Drug discovery in the 21st century: an introduction / Shayne C. Gad -- Natural products / Charles B. Spainhour -- Cancer cell proteomics using molecular aptamers / Weihong Tan, Zehui Cao, Dihua Shangguang -- Molecular similarity methods and QSAR models as tools for virtual screening / Jürgen Bajorath -- Systems biology: applications in drug discovery / Sean Ekins ...[et al.] -- High throughput flow cytometry / Larry A. Sklar ... [et al.] -- Combining NMR spectral information with associated structural features to form computationally non-intensive, rugged, and objective models of biological activity / Richard Beger, Dan A. Buzatu, Jon G. Wilkes -- Using Microsoft Excel as a laboratory data management tool / A. Erik Rubin, Mark F. Russo, William Neil -- The age of regulation / Sandy Weinberg, Gerald J. Whartenby -- Simultaneous screening of multiple cell lines using the CellCardtm system / Oren E. Beske -- Protein x-ray crystallography in drug discovery / Peter Nollert ...[et al.] -- Biological and chemistry assays available during drug discovery and developability assessment / Duane B. Lakings -- Strategies and methods in monitoring and targeting protein-protein interactions / Arianna Loregian, Giorgio Palù -- High throughput screening: evolution of technology and methods -- Martyn N. Banks ... [et al.] -- Metal-enhanced fluorescence: application to high-throughput screening and drug discovery / Kadir Aslan .. [et al,] -- Methods for the design and analysis of replicate-experiment studies to establish assay reproducibility and the equivalence of two potency assays / Brian J. Eastwood ... [et al.] -- Coupled luminescent methods in drug discovery: three-minute assays for cytotoxicity and phosphatase activity / Michael J. Corey, Robert J. Kinders -- Design and pharmaceutical applications of prodrugs / Tomi Jarvinen ... [et al.] -- GABA and glutamate receptor ligands and their therapeutic potential in CNS disorders / Ulf Madsen ... [et al.] -- Cardiac sarcolemmal ATP-sensitive potassium channel antagonists: novel ischemia-selective antiarrhythmic agents / George E. Billman -- Factors influencing the efficacy of mediator-specific anti-inflammatory, glucocorticoid and anti-coagulant therapies for sepsis / Peter C. Minneci ... [et al.] -- Combinatorial chemistry in the drug discovery process / Nathan T. Ross, Brian R. McNaughton, Benjamin L. Miller -- Herbal medicines and animal models of gastrointestinal diseases / C.H. Cho, J.K.S. Ko -- Endocrine and metabolic agents / Brian L. Furman -- Respiratory viruses / Paul D. Olivo -- Strategies in the design of antiviral drugs / Erik De Clercq, Piet Herdewijn -- Protein kinase inhibitors in drug discovery / Keykavous Parang, Gongqin Sun -- RNA-based therapies / Ingmar Hoerr, Steve Pascolo -- Novel imaging agents for molecular MR imaging of cancer / Dmitri Artemov, Zaver M. Bhujwalla -- Genomics-based drug discovery / Spyro Mousses -- Cancer drug discovery / Susan Mooberry. |
| Record Nr. | UNINA-9910783437503321 |
| Hoboken, N.J., : Wiley-Interscience, c2005 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Drug discovery handbook [[electronic resource] /] / edited by Shayne Cox Gad
| Drug discovery handbook [[electronic resource] /] / edited by Shayne Cox Gad |
| Edizione | [1st ed.] |
| Pubbl/distr/stampa | Hoboken, N.J., : Wiley-Interscience, c2005 |
| Descrizione fisica | 1 online resource (1493 p.) |
| Disciplina | 615/.19 |
| Altri autori (Persone) | GadShayne C. <1948-> |
| Collana | Pharmaceutical Development Series |
| Soggetto topico |
Drugs - Research
Drug development Drugs - Design Pharmaceutical chemistry |
| ISBN |
1-280-27707-6
9786610277070 0-470-30589-4 0-471-72877-2 0-471-72878-0 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Drug discovery in the 21st century: an introduction / Shayne C. Gad -- Natural products / Charles B. Spainhour -- Cancer cell proteomics using molecular aptamers / Weihong Tan, Zehui Cao, Dihua Shangguang -- Molecular similarity methods and QSAR models as tools for virtual screening / Jürgen Bajorath -- Systems biology: applications in drug discovery / Sean Ekins ...[et al.] -- High throughput flow cytometry / Larry A. Sklar ... [et al.] -- Combining NMR spectral information with associated structural features to form computationally non-intensive, rugged, and objective models of biological activity / Richard Beger, Dan A. Buzatu, Jon G. Wilkes -- Using Microsoft Excel as a laboratory data management tool / A. Erik Rubin, Mark F. Russo, William Neil -- The age of regulation / Sandy Weinberg, Gerald J. Whartenby -- Simultaneous screening of multiple cell lines using the CellCardtm system / Oren E. Beske -- Protein x-ray crystallography in drug discovery / Peter Nollert ...[et al.] -- Biological and chemistry assays available during drug discovery and developability assessment / Duane B. Lakings -- Strategies and methods in monitoring and targeting protein-protein interactions / Arianna Loregian, Giorgio Palù -- High throughput screening: evolution of technology and methods -- Martyn N. Banks ... [et al.] -- Metal-enhanced fluorescence: application to high-throughput screening and drug discovery / Kadir Aslan .. [et al,] -- Methods for the design and analysis of replicate-experiment studies to establish assay reproducibility and the equivalence of two potency assays / Brian J. Eastwood ... [et al.] -- Coupled luminescent methods in drug discovery: three-minute assays for cytotoxicity and phosphatase activity / Michael J. Corey, Robert J. Kinders -- Design and pharmaceutical applications of prodrugs / Tomi Jarvinen ... [et al.] -- GABA and glutamate receptor ligands and their therapeutic potential in CNS disorders / Ulf Madsen ... [et al.] -- Cardiac sarcolemmal ATP-sensitive potassium channel antagonists: novel ischemia-selective antiarrhythmic agents / George E. Billman -- Factors influencing the efficacy of mediator-specific anti-inflammatory, glucocorticoid and anti-coagulant therapies for sepsis / Peter C. Minneci ... [et al.] -- Combinatorial chemistry in the drug discovery process / Nathan T. Ross, Brian R. McNaughton, Benjamin L. Miller -- Herbal medicines and animal models of gastrointestinal diseases / C.H. Cho, J.K.S. Ko -- Endocrine and metabolic agents / Brian L. Furman -- Respiratory viruses / Paul D. Olivo -- Strategies in the design of antiviral drugs / Erik De Clercq, Piet Herdewijn -- Protein kinase inhibitors in drug discovery / Keykavous Parang, Gongqin Sun -- RNA-based therapies / Ingmar Hoerr, Steve Pascolo -- Novel imaging agents for molecular MR imaging of cancer / Dmitri Artemov, Zaver M. Bhujwalla -- Genomics-based drug discovery / Spyro Mousses -- Cancer drug discovery / Susan Mooberry. |
| Record Nr. | UNINA-9910814350203321 |
| Hoboken, N.J., : Wiley-Interscience, c2005 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Drug discovery research [[electronic resource] ] : new frontiers in the post-genomic era / / edited by Ziwei Huang
| Drug discovery research [[electronic resource] ] : new frontiers in the post-genomic era / / edited by Ziwei Huang |
| Pubbl/distr/stampa | Hoboken, N.J., : Wiley-Interscience, c2007 |
| Descrizione fisica | 1 online resource (560 p.) |
| Disciplina |
615.19
615/.19 |
| Altri autori (Persone) | HuangZiwei <1965-> |
| Soggetto topico |
Drugs - Design
Biopharmaceutics Pharmaceutical chemistry |
| ISBN |
1-280-90025-3
9786610900251 0-470-13186-1 0-470-13185-3 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Molecular docking and structure-based design / P. Therese Lang ... [et al.] -- Recent advances in drug discovery research using structure-based virtual screening techniques : examples of success for diverse protein targets / Sutapa Ghosh ... [et al.] -- Virtual screening in drug discovery / Malcolm J. McGregor, Zhaowen Luo, and Xuliang Jiang -- Computer-aided drug design / Grace Shiahuy Chen and Ji-Wang Chern -- Focused library design based on hit and target structures : method and application in drug discovery / Weiliang Zhu ... [et al.] --
Beyond natural products : synthetic analogs of bryostatin 1 / Paul A. Wender ... [et al.] -- The promises and pitfalls of small-molecule inhibition of poly(ADP-ribose) glycohydrolase (PARG) / Amanda C. Nottbohm and Paul J. Hergenrother -- Cyclic ADP-ribose analogues with minimal structure : synthesis and calcium-release activity / Lihe Zhang and Andreas H. Guse -- Evaluation of neuroimmunophilin ligands / Junhai Xiao, Aihua Nie, and Song Li -- Chiral drugs and the associated asymmetric synthesis / Jiange Zhang and Guoqiang Lin -- Alpha-helix mimetics in drug discovery / Hang Yin, Gui-In Lee, and Andrew D. Hamilton -- Basic and translational research of chemokine ligands and receptors and development of novel therapeutics / Won-Tak Choi ... [et al.] -- Research progress in protein post-translational modification / Jia Hu, Yanting Guo, and Yanmei Li -- Controlled release of antibiotics encapsulated in nanoporous sol-gel materials with tunable pore parameters / Houping Yin, Laura Zheng, and Yen Wei -- Retinoic acid and arsenic trioxide treatment in acute promyelocytic leukemia : a model of oncoprotein targeted therapy / Jian-Hua Tong, Sai-Juan Chen, and Zhu Chen. 2-chlorodeoxyadenosine (cladribine) : rational development of a novel chemotherapeutic agent / Howard B. Cottam and Dennis A. Carson -- Apoptosis-based drug discovery for cancer / John C. Reed ... [et al.] -- Mechanism-based development of memantine as a therapeutic agent in treating Alzheimer's disease and other neurologic disorders : low-affinity, uncompetitive antagonism with fast off-rate / Huei-Sheng Vincent Chen and Stuart A. Lipton -- Bridging bench to clinic : roles of animal models for post-genomics drug discovery on metabolic diseases / Chi-Wai Wong and Ling Chen -- Stem cell research and applications for human therapies / Prithi Rajan ... [et al.]. |
| Record Nr. | UNINA-9910143576203321 |
| Hoboken, N.J., : Wiley-Interscience, c2007 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Drug discovery research [[electronic resource] ] : new frontiers in the post-genomic era / / edited by Ziwei Huang
| Drug discovery research [[electronic resource] ] : new frontiers in the post-genomic era / / edited by Ziwei Huang |
| Pubbl/distr/stampa | Hoboken, N.J., : Wiley-Interscience, c2007 |
| Descrizione fisica | 1 online resource (560 p.) |
| Disciplina |
615.19
615/.19 |
| Altri autori (Persone) | HuangZiwei <1965-> |
| Soggetto topico |
Drugs - Design
Biopharmaceutics Pharmaceutical chemistry |
| ISBN |
1-280-90025-3
9786610900251 0-470-13186-1 0-470-13185-3 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Molecular docking and structure-based design / P. Therese Lang ... [et al.] -- Recent advances in drug discovery research using structure-based virtual screening techniques : examples of success for diverse protein targets / Sutapa Ghosh ... [et al.] -- Virtual screening in drug discovery / Malcolm J. McGregor, Zhaowen Luo, and Xuliang Jiang -- Computer-aided drug design / Grace Shiahuy Chen and Ji-Wang Chern -- Focused library design based on hit and target structures : method and application in drug discovery / Weiliang Zhu ... [et al.] --
Beyond natural products : synthetic analogs of bryostatin 1 / Paul A. Wender ... [et al.] -- The promises and pitfalls of small-molecule inhibition of poly(ADP-ribose) glycohydrolase (PARG) / Amanda C. Nottbohm and Paul J. Hergenrother -- Cyclic ADP-ribose analogues with minimal structure : synthesis and calcium-release activity / Lihe Zhang and Andreas H. Guse -- Evaluation of neuroimmunophilin ligands / Junhai Xiao, Aihua Nie, and Song Li -- Chiral drugs and the associated asymmetric synthesis / Jiange Zhang and Guoqiang Lin -- Alpha-helix mimetics in drug discovery / Hang Yin, Gui-In Lee, and Andrew D. Hamilton -- Basic and translational research of chemokine ligands and receptors and development of novel therapeutics / Won-Tak Choi ... [et al.] -- Research progress in protein post-translational modification / Jia Hu, Yanting Guo, and Yanmei Li -- Controlled release of antibiotics encapsulated in nanoporous sol-gel materials with tunable pore parameters / Houping Yin, Laura Zheng, and Yen Wei -- Retinoic acid and arsenic trioxide treatment in acute promyelocytic leukemia : a model of oncoprotein targeted therapy / Jian-Hua Tong, Sai-Juan Chen, and Zhu Chen. 2-chlorodeoxyadenosine (cladribine) : rational development of a novel chemotherapeutic agent / Howard B. Cottam and Dennis A. Carson -- Apoptosis-based drug discovery for cancer / John C. Reed ... [et al.] -- Mechanism-based development of memantine as a therapeutic agent in treating Alzheimer's disease and other neurologic disorders : low-affinity, uncompetitive antagonism with fast off-rate / Huei-Sheng Vincent Chen and Stuart A. Lipton -- Bridging bench to clinic : roles of animal models for post-genomics drug discovery on metabolic diseases / Chi-Wai Wong and Ling Chen -- Stem cell research and applications for human therapies / Prithi Rajan ... [et al.]. |
| Record Nr. | UNINA-9910830812503321 |
| Hoboken, N.J., : Wiley-Interscience, c2007 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Drug discovery today Biosilico
| Drug discovery today Biosilico |
| Pubbl/distr/stampa | [Amsterdam] ; ; [New York], : Elsevier Science, 2004 |
| Descrizione fisica | 1 online resource |
| Soggetto topico |
Drugs - Design
Drugs - Design - Data processing Biochemistry - Data processing Drugs - Computer simulation Drug Design Medical Informatics Simulation par ordinateur Développement de médicaments Informatique médicale |
| Soggetto genere / forma |
Periodical
Periodicals. Périodique électronique (Descripteur de forme) Ressource Internet (Descripteur de forme) |
| Soggetto non controllato | Pharmacy, Therapeutics, & Pharmacology |
| ISSN | 1878-0997 |
| Formato | Materiale a stampa |
| Livello bibliografico | Periodico |
| Lingua di pubblicazione | eng |
| Altri titoli varianti |
Biosilico
DDT. |
| Record Nr. | UNINA-9910143062703321 |
| [Amsterdam] ; ; [New York], : Elsevier Science, 2004 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Drug discovery today Targets
| Drug discovery today Targets |
| Pubbl/distr/stampa | [Amsterdam] ; ; [New York], : Elsevier Science, -2004 |
| Disciplina | 572.86 |
| Soggetto topico |
Drugs - Design
Gene therapy Medical genetics Drug Design Genomics Proteomics Médicament Thérapie génique Génétique médicale |
| Soggetto genere / forma |
Periodical
Periodicals. Périodique électronique (Descripteur de forme) Ressource Internet (Descripteur de forme) |
| Soggetto non controllato | Pharmacy, Therapeutics, & Pharmacology |
| ISSN | 1878-7363 |
| Formato | Materiale a stampa |
| Livello bibliografico | Periodico |
| Lingua di pubblicazione | eng |
| Altri titoli varianti |
Targets
DDT. |
| Record Nr. | UNINA-9910143062503321 |
| [Amsterdam] ; ; [New York], : Elsevier Science, -2004 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Drug discovery today Targets
| Drug discovery today Targets |
| Pubbl/distr/stampa | [Amsterdam] ; ; [New York], : Elsevier Science, -2004 |
| Disciplina | 572.86 |
| Soggetto topico |
Drugs - Design
Gene therapy Medical genetics Drug Design Genomics Proteomics Médicament Thérapie génique Génétique médicale |
| Soggetto genere / forma |
Periodical
Periodicals. Périodique électronique (Descripteur de forme) Ressource Internet (Descripteur de forme) |
| Soggetto non controllato | Pharmacy, Therapeutics, & Pharmacology |
| ISSN | 1878-7363 |
| Formato | Materiale a stampa |
| Livello bibliografico | Periodico |
| Lingua di pubblicazione | eng |
| Altri titoli varianti |
Targets
DDT. |
| Record Nr. | UNISA-996198117603316 |
| [Amsterdam] ; ; [New York], : Elsevier Science, -2004 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. di Salerno | ||
| ||
Drug discovery today Biosilico
| Drug discovery today Biosilico |
| Pubbl/distr/stampa | [Amsterdam] ; ; [New York], : Elsevier Science, 2004 |
| Descrizione fisica | 1 online resource |
| Soggetto topico |
Drugs - Design
Drugs - Design - Data processing Biochemistry - Data processing Drugs - Computer simulation Drug Design Medical Informatics Simulation par ordinateur Développement de médicaments Informatique médicale |
| Soggetto genere / forma |
Periodical
Periodicals. Périodique électronique (Descripteur de forme) Ressource Internet (Descripteur de forme) |
| Soggetto non controllato | Pharmacy, Therapeutics, & Pharmacology |
| ISSN | 1878-0997 |
| Formato | Materiale a stampa |
| Livello bibliografico | Periodico |
| Lingua di pubblicazione | eng |
| Altri titoli varianti |
Biosilico
DDT. |
| Record Nr. | UNISA-996198117903316 |
| [Amsterdam] ; ; [New York], : Elsevier Science, 2004 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. di Salerno | ||
| ||
Drug discovery today Technologies
| Drug discovery today Technologies |
| Pubbl/distr/stampa | [Oxford], : Elsevier, 2004-2021 |
| Descrizione fisica | 1 online resource |
| Soggetto topico |
Drug development
Physiology, Pathological Drugs - Design Technology, Pharmaceutical - trends Drug Design |
| Soggetto genere / forma |
Periodical
Fulltext Internet Resources. Periodicals. |
| Soggetto non controllato | Pharmacy, Therapeutics, & Pharmacology |
| ISSN | 1740-6749 |
| Formato | Materiale a stampa |
| Livello bibliografico | Periodico |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Technologies |
| Record Nr. | UNISA-996216406803316 |
| [Oxford], : Elsevier, 2004-2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. di Salerno | ||
| ||
Soggetto topico
-
Drugs - Design
(283)
- Pharmaceutical chemistry (86)
- Drug development (61)
- Drug Design (35)
- Drug delivery systems (16)