Info
- Utilizzare la checkbox di selezione a fianco di ciascun documento per attivare le funzionalità di stampa, invio email, download nei formati disponibili del (i) record.
Development of therapeutic agents handbook / / [edited by] Shayne Cox Gad
| Development of therapeutic agents handbook / / [edited by] Shayne Cox Gad |
| Edizione | [1st ed.] |
| Pubbl/distr/stampa | Hoboken, N.J., : John Wiley & Sons, c2012 |
| Descrizione fisica | 1 online resource (1278 p.) |
| Disciplina | 615/.19 |
| Altri autori (Persone) | GadShayne C. <1948-> |
| Collana | Pharmaceutical Development Series |
| Soggetto topico |
Drugs - Research
Drugs - Design Pharmaceutical chemistry Drug development |
| ISBN |
1-118-07711-3
1-283-31590-4 9786613315908 1-118-07710-5 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | pt. 1. Fundamentals and concepts -- pt. 2. Methods and techniques in drug discovery and development -- pt. 3. Therapeutics topics. |
| Record Nr. | UNINA-9910808987003321 |
| Hoboken, N.J., : John Wiley & Sons, c2012 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Discovery DMPK quick guide : guide to data interpretation and integration / / S. Cyrus Khojasteh [and three others]
| Discovery DMPK quick guide : guide to data interpretation and integration / / S. Cyrus Khojasteh [and three others] |
| Pubbl/distr/stampa | Cham, Switzerland : , : Springer International Publishing, , [2022] |
| Descrizione fisica | 1 online resource (241 pages) |
| Disciplina | 615.19 |
| Soggetto topico |
Drug development
Drugs - Design |
| ISBN | 3-031-10691-1 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Goals for DMPK during drug optimizations -- Drug Properties -- DMPK in lead optimization -- Candidate translational characterization -- Q&A of DMPK issues and tools for drug discovery -- ADME assays -- Regulatory documents for IND to Support FIH -- Appendix: Chemical nomenclature. |
| Record Nr. | UNINA-9910634041203321 |
| Cham, Switzerland : , : Springer International Publishing, , [2022] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Dosage form design considerations . Volume I / / edited by Rakesh K. Tekade
| Dosage form design considerations . Volume I / / edited by Rakesh K. Tekade |
| Pubbl/distr/stampa | London, United Kingdom : , : Academic Press, an imprint of Elsevier, , [2018] |
| Descrizione fisica | 1 online resource (881 pages) : illustrations |
| Disciplina | 615.1900285 |
| Collana | Advances in pharmaceutical product development and research series |
| Soggetto topico |
Drugs - Design
Drugs - Dosage forms Drug development |
| ISBN |
9780128144237
0128144238 9780128144244 (electronic bk.) 0128144246 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | 1. Preformulation in Drug Research and Pharmaceutical product development 2. Physicochemical aspects to be considered in pharmaceutical product development 3. Role of physicochemical parameters on drug absorption and their implication in pharmaceutical product development 4. Physiologic factors related to drug absorption 5. Physicochemical, pharmaceutical, and biological considerations in GIT absorption of drugs 6. Influence of drug properties and routes of drug administration on the design of controlled release system 7. Stability and degradation studies for drug and drug product 8. First-pass metabolism considerations in pharmaceutical product development 9. Dissolution profile consideration in pharmaceutical product development 10. Drug disposition considerations in pharmaceutical product 11. Protein and tissue binging: implication on pharmacokinetic parameters 12. Preformulation studies of drug substances, protein, and Peptides: Role in drug discovery and pharmaceutical product development 13. Role of salt selection in drug discovery and development 14. Drug complexation: implications in drug solubilization and oral bioavailability enhancement 15. Solubility and solubilization approaches in pharmaceutical product development 16. Rheology and its implications on performance of liquid dosage forms 17. Micromeritics in pharmaceutical product development 18. Four stages of pharmaceutical product development: preformulation, prototype development and scale-up, biological aspects, and commercialization 19. Scale-up studies in pharmaceutical products development 20. Manipulation of physiological processes for pharmaceutical product development 21. Impact of pharmaceutical product quality on clinical efficacy 22. Formulation additives used in pharmaceutical products: emphasis on regulatory perspectives and GRAS |
| Record Nr. | UNINA-9910583085103321 |
| London, United Kingdom : , : Academic Press, an imprint of Elsevier, , [2018] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Dosage form design parameters . Volume II / / edited by Rakesh K. Tekade
| Dosage form design parameters . Volume II / / edited by Rakesh K. Tekade |
| Pubbl/distr/stampa | London, United Kingdom : , : Academic Press, an imprint of Elsevier, , [2018] |
| Descrizione fisica | 1 online resource (816 pages) |
| Disciplina | 615.4 |
| Collana | Advances in pharmaceutical product development and research series |
| Soggetto topico |
Drugs - Dosage forms
Drugs - Design |
| ISBN |
9780128144220
9780128144213 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910583039303321 |
| London, United Kingdom : , : Academic Press, an imprint of Elsevier, , [2018] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Drug Design : Novel Advances in the Omics Field and Applications / / Arli Aditya Parikesit, editor
| Drug Design : Novel Advances in the Omics Field and Applications / / Arli Aditya Parikesit, editor |
| Pubbl/distr/stampa | London : , : IntechOpen, , [2021] |
| Descrizione fisica | 1 online resource (158 pages) : illustrations |
| Disciplina | 615.19 |
| Soggetto topico |
Drugs - Design
Structural bioinformatics |
| ISBN | 1-78984-753-2 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Drug Design |
| Record Nr. | UNINA-9910490733703321 |
| London : , : IntechOpen, , [2021] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Drug design : novel advances in the omics field and applications / / edited by Arli Aditya Parikesit
| Drug design : novel advances in the omics field and applications / / edited by Arli Aditya Parikesit |
| Pubbl/distr/stampa | London : , : IntechOpen, , 2021 |
| Descrizione fisica | 1 online resource (131 pages) |
| Disciplina | 615.19 |
| Soggetto topico | Drugs - Design |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Drug Design |
| Record Nr. | UNINA-9910688427503321 |
| London : , : IntechOpen, , 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Drug design [[electronic resource] ] : cutting edge approaches / / edited by Darren R. Flower
| Drug design [[electronic resource] ] : cutting edge approaches / / edited by Darren R. Flower |
| Pubbl/distr/stampa | Cambridge, U.K., : Royal Society of Chemistry, c2002 |
| Descrizione fisica | 1 online resource (204 p.) |
| Disciplina | 615.19 |
| Altri autori (Persone) | FlowerDarren R |
| Collana | Special publication |
| Soggetto topico |
Drugs - Design
Drugs - Design - Mathematical models Artificial intelligence - Medical applications Drugs - Research - Methodology |
| Soggetto genere / forma | Electronic books. |
| ISBN |
1-84755-070-3
1-60119-027-1 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | CONTENTS; Molecular Informatics: Sharpening Drug Design's Cutting Edge; High-Throughput X-Ray Crystallography for Drug Discovery; Trawling the Genome for G Protein-coupled Receptors: the Importance of Integrating Bioinformatic Approaches; Virtual Screening of Virtual Libraries - an Efficient Strategy for LeadGeneration; Virtual Techniques for Lead Optimisation; The Impact of Physical Organic Chemistry on the Control of Drug-likeProperties; Mutagenesis and Modelling Highlight the Critical Nature of theTM2-loop-TM3 Region of Biogenic Amine GPCRS; Computational Vaccine Design; Subject Index |
| Record Nr. | UNINA-9910450162003321 |
| Cambridge, U.K., : Royal Society of Chemistry, c2002 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Drug design : cutting edge approaches / / editor, Darren R. Flower
| Drug design : cutting edge approaches / / editor, Darren R. Flower |
| Pubbl/distr/stampa | Cambridge : , : Royal Society of Chemistry, , 2002 |
| Descrizione fisica | 1 online resource (x, 192 pages) : illustrations |
| Disciplina | 615.19 |
| Altri autori (Persone) | FlowerDarren R |
| Collana | Special publication |
| Soggetto topico |
Drugs - Design
Drugs - Design - Mathematical models Artificial intelligence - Medical applications Drugs - Research - Methodology |
| ISBN |
1-84755-070-3
1-60119-027-1 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | CONTENTS; Molecular Informatics: Sharpening Drug Design's Cutting Edge; High-Throughput X-Ray Crystallography for Drug Discovery; Trawling the Genome for G Protein-coupled Receptors: the Importance of Integrating Bioinformatic Approaches; Virtual Screening of Virtual Libraries - an Efficient Strategy for LeadGeneration; Virtual Techniques for Lead Optimisation; The Impact of Physical Organic Chemistry on the Control of Drug-likeProperties; Mutagenesis and Modelling Highlight the Critical Nature of theTM2-loop-TM3 Region of Biogenic Amine GPCRS; Computational Vaccine Design; Subject Index |
| Record Nr. | UNINA-9910783441703321 |
| Cambridge : , : Royal Society of Chemistry, , 2002 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Drug design : cutting edge approaches / / editor, Darren R. Flower
| Drug design : cutting edge approaches / / editor, Darren R. Flower |
| Pubbl/distr/stampa | Cambridge : , : Royal Society of Chemistry, , 2002 |
| Descrizione fisica | 1 online resource (x, 192 pages) : illustrations |
| Disciplina | 615.19 |
| Altri autori (Persone) | FlowerDarren R |
| Collana | Special publication |
| Soggetto topico |
Drugs - Design
Drugs - Design - Mathematical models Artificial intelligence - Medical applications Drugs - Research - Methodology |
| ISBN |
1-84755-070-3
1-60119-027-1 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | CONTENTS; Molecular Informatics: Sharpening Drug Design's Cutting Edge; High-Throughput X-Ray Crystallography for Drug Discovery; Trawling the Genome for G Protein-coupled Receptors: the Importance of Integrating Bioinformatic Approaches; Virtual Screening of Virtual Libraries - an Efficient Strategy for LeadGeneration; Virtual Techniques for Lead Optimisation; The Impact of Physical Organic Chemistry on the Control of Drug-likeProperties; Mutagenesis and Modelling Highlight the Critical Nature of theTM2-loop-TM3 Region of Biogenic Amine GPCRS; Computational Vaccine Design; Subject Index |
| Record Nr. | UNINA-9910814355903321 |
| Cambridge : , : Royal Society of Chemistry, , 2002 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Drug design of zinc-enzyme inhibitors [[electronic resource] ] : functional, structural, and disease applications / / edited by Claudiu T. Supuran, Jean-Yves Winum
| Drug design of zinc-enzyme inhibitors [[electronic resource] ] : functional, structural, and disease applications / / edited by Claudiu T. Supuran, Jean-Yves Winum |
| Pubbl/distr/stampa | Hoboken, NJ, : John Wiley & Sons, c2009 |
| Descrizione fisica | 1 online resource (1072 p.) |
| Disciplina | 615/.19 |
| Altri autori (Persone) |
SupuranClaudiu T. <1962->
WinumJean-Yves |
| Collana | Wiley Series in Drug Discovery and Development |
| Soggetto topico |
Zinc enzymes - Inhibitors - Therapeutic use
Drugs - Design |
| ISBN |
1-282-34608-3
9786612346088 0-470-50816-7 0-470-50815-9 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
DRUG DESIGN OF ZINC-ENZYME INHIBITORS; CONTENTS; PREFACE; CONTRIBUTORS; PART I INTRODUCTION; 1. Introduction to Zinc Enzymes as Drug Targets; PART II DRUG DESIGN OF CARBONIC ANHYDRASE INHIBITORS AND ACTIVATORS; 2. Carbonic Anhydrases as Drug Targets: General Presentation; 3. Zinc Binding Functions in the Design of Carbonic Anhydrase Inhibitors; 4. X-Ray Crystallography of Carbonic Anhydrase Inhibitors and Its Importance in Drug Design; 5. Antiglaucoma Carbonic Anhydrase Inhibitors as Ophthalomologic Drugs
6. Diuretics with Carbonic Anhydrase Inhibitory Activity: Toward Novel Applications for Sulfonamide Drugs7. Drug Design of Carbonic Anhydrase Inhibitors as Anticonvulsant Agents; 8. Carbonic Anhydrase Inhibitors Targeting Cancer: Therapeutic, Immunologic, and Diagnostic Tools Targeting Isoforms IX and XII; 9. Fluorescent- and Spin-Labeled Sulfonamides as Probe for Carbonic Anhydrase IX; 10. Drug Design of Antiobesity Carbonic Anhydrase Inhibitors; 11. Dual Carbonic Anhydrase and Cyclooxygenase-2 Inhibition 12. Advances in the Inhibitory and Structural Investigations on Carbonic Anhydrase Isozymes XIII and XV13. Mechanism and Inhibition of the β-Class and γ-Class Carbonic Anhydrases; 14. Fungal and Nematode Carbonic Anhydrases: Their Inhibition in Drug Design; 15. Crystallographic Studies on Carbonic Anhydrases from Fungal Pathogens for Structure-Assisted Drug Development; 16. Malaria Parasite Carbonic Anhydrase and Its Inhibition in the Development of Novel Therapies of Malaria; 17. Inhibitors of Helicobacter pylori α- and β-Carbonic Anhydrases as Novel Drugs for Gastroduodenal Diseases 18. QSAR of Carbonic Anhydrase Inhibitors and Their Impact on Drug Design19. Selectivity Issues in the Design of CA Inhibitors; 20. Bicarbonate Transport Metabolons; 21. Metal Complexes of Sulfonamides as Dual Carbonic Anhydrase Inhibitors; 22. Drug Design Studies of Carbonic Anhydrase Activators; PART III DRUG DESIGN OF MATRIX METALLOPROTEINASE INHIBITORS; 23. Matrix Metalloproteinases: An Overview; 24. MMP Inhibitors Based on Earlier Succinimide Strategies: From Early to New Approaches; 25. Drug Design of Sulfonylated MMP Inhibitors; 26. ADAMs and ADAMTs Selective Synthetic Inhibitors 27. QSAR Studies of MMP InhibitorsPART IV DRUG DESIGN OF BACTERIAL ZINC PROTEASE INHIBITORS; 28. Bacterial Zinc Proteases as Orphan Targets; 29. Botulinus Toxin, Tetanus Toxin, and Anthrax Lethal Factor Inhibitors; 30. Clostridium histolyticum Collagenase Inhibitors in the Drug Design; 31. Other Bacterial Zinc Peptidases as Potential Drug Targets; PART V DRUG DESIGN STUDIES OF OTHER ZINC-CONTAINING ENZYMES; 32. Angiotensin Converting Enzyme (ACE) Inhibitors; 33. P-III Metalloproteinase (Leucurolysin-B) from Bothrops leucurus Venom: Isolation and Possible Inhibition 34. CaaX-Protein Prenyltransferase Inhibitors |
| Record Nr. | UNINA-9910139879003321 |
| Hoboken, NJ, : John Wiley & Sons, c2009 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Soggetto topico
-
Drugs - Design
(310)
- Pharmaceutical chemistry (91)
- Drug development (68)
- Drug Design (35)
- Biopharmaceutics (16)