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Nutraceuticals and natural product derivatives : disease prevention & drug discovery / / edited by Mohammad Fahad Ullah, Aamir Ahmad
| Nutraceuticals and natural product derivatives : disease prevention & drug discovery / / edited by Mohammad Fahad Ullah, Aamir Ahmad |
| Pubbl/distr/stampa | Hoboken, NJ : , : Wiley Blackwell, , 2019 |
| Descrizione fisica | 1 online resource (453 pages) |
| Disciplina | 615.19 |
| Soggetto topico |
Drugs - Design
Natural products |
| ISBN |
1-119-43673-7
1-119-43671-0 1-119-43669-9 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Natural food sources for the control of glycemia and the prevention of diabetic complications / Carlo Pesce, Carla Iacobini, Stefano Menini -- Anti-aging effects of sulfur containing amino acids and nutraceuticals / Geetika Garg, Abhishek Kumar Singh, Sandeep Singh, Syed Ibrahim Rizvi -- Garcinia fruits : their potential to combat metabolic syndrome / Oliver John, Lindsay Brown, Sunil K. Panchal -- Pro-angiogenic and anti-angiogenic effects of small molecules from natural products / Jingyi Ma, Xuelin Zhou -- Nutraceuticals & natural product derivatives in the premises of disease prevention / Mohammad Fahad Ullah, Showket Hussain Bhat, Faisel M. Abu-duhier -- Honey and propolis mediated regulation of protein network in cancer cells / Ammad Ahmad Farooqi, Mirna Azalea Romero, Aliye Aras, Muhammad Zahid Qureshi, Lara Hanna Wakim -- Anti-proliferative effects and mechanism of action of phytosterols derived from bioactive plant extracts / Gabriel López-garcía, Amparo Alegría, Reyes Barberá, Antonio Cilla -- Yerba mate (Ilex paraguariensis a. st. hil.) : a promising adjuvant in the treatment of diabetes, obesity and metabolic syndrome / Vanesa Gesser Correa, Rúbia Carvalho Gomes Corra, Tatiane Francielli Vieira, Eloá Angelica Koehnlein, Adelar Bracht, Rosane Marina Peralta -- Role of natural antioxidants from selected plants belonging to family Scrophulariaceae and Buddlejaceae in prevention and treatment of neurodegenerative diseases / Cigdem Kahraman, Zeliha S. Akdemir, I. Irem Tatli -- Recent trends in drug discovery against Alzheimer's disease : use of natural products and nutraceuticals from botanicals / Sudatta Maity, Samapika Nandy, Abhijit Dey -- Therapeutic potential of metallo- herbal nanoceuticals : current status & future perspective / Shazia Usmani, Muhammad Arif , Syed Misbah Hasan -- Green tea polyphenols : a putative mechanism for cytotoxic action against cancer cells / Mohd Farhan, Uzma Shamim, Asim Rizvi, Sandesh Chibber, SM Hadi -- Nature's armamentarium against malaria : antimalarials and their semi-synthetic derivatives / Fyaz MD Ismail -- Nutraceutical based pharmacological intervention in the management of liver diseases / Aaliya Shah, Syed Mudassar. |
| Record Nr. | UNINA-9910527340303321 |
| Hoboken, NJ : , : Wiley Blackwell, , 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Nutraceuticals and natural product derivatives : disease prevention & drug discovery / / edited by Mohammad Fahad Ullah, Aamir Ahmad
| Nutraceuticals and natural product derivatives : disease prevention & drug discovery / / edited by Mohammad Fahad Ullah, Aamir Ahmad |
| Pubbl/distr/stampa | Hoboken, NJ : , : Wiley Blackwell, , 2019 |
| Descrizione fisica | 1 online resource (453 pages) |
| Disciplina | 615.19 |
| Soggetto topico |
Drugs - Design
Natural products |
| ISBN |
1-119-43673-7
1-119-43671-0 1-119-43669-9 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Natural food sources for the control of glycemia and the prevention of diabetic complications / Carlo Pesce, Carla Iacobini, Stefano Menini -- Anti-aging effects of sulfur containing amino acids and nutraceuticals / Geetika Garg, Abhishek Kumar Singh, Sandeep Singh, Syed Ibrahim Rizvi -- Garcinia fruits : their potential to combat metabolic syndrome / Oliver John, Lindsay Brown, Sunil K. Panchal -- Pro-angiogenic and anti-angiogenic effects of small molecules from natural products / Jingyi Ma, Xuelin Zhou -- Nutraceuticals & natural product derivatives in the premises of disease prevention / Mohammad Fahad Ullah, Showket Hussain Bhat, Faisel M. Abu-duhier -- Honey and propolis mediated regulation of protein network in cancer cells / Ammad Ahmad Farooqi, Mirna Azalea Romero, Aliye Aras, Muhammad Zahid Qureshi, Lara Hanna Wakim -- Anti-proliferative effects and mechanism of action of phytosterols derived from bioactive plant extracts / Gabriel López-garcía, Amparo Alegría, Reyes Barberá, Antonio Cilla -- Yerba mate (Ilex paraguariensis a. st. hil.) : a promising adjuvant in the treatment of diabetes, obesity and metabolic syndrome / Vanesa Gesser Correa, Rúbia Carvalho Gomes Corra, Tatiane Francielli Vieira, Eloá Angelica Koehnlein, Adelar Bracht, Rosane Marina Peralta -- Role of natural antioxidants from selected plants belonging to family Scrophulariaceae and Buddlejaceae in prevention and treatment of neurodegenerative diseases / Cigdem Kahraman, Zeliha S. Akdemir, I. Irem Tatli -- Recent trends in drug discovery against Alzheimer's disease : use of natural products and nutraceuticals from botanicals / Sudatta Maity, Samapika Nandy, Abhijit Dey -- Therapeutic potential of metallo- herbal nanoceuticals : current status & future perspective / Shazia Usmani, Muhammad Arif , Syed Misbah Hasan -- Green tea polyphenols : a putative mechanism for cytotoxic action against cancer cells / Mohd Farhan, Uzma Shamim, Asim Rizvi, Sandesh Chibber, SM Hadi -- Nature's armamentarium against malaria : antimalarials and their semi-synthetic derivatives / Fyaz MD Ismail -- Nutraceutical based pharmacological intervention in the management of liver diseases / Aaliya Shah, Syed Mudassar. |
| Record Nr. | UNINA-9910813548803321 |
| Hoboken, NJ : , : Wiley Blackwell, , 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
The organic chemistry of drug design and drug action / / Richard B. Silverman, Northwestern University, Department of Chemistry, Department of Molecular Biosciences, Chemistry of Life Processes Institute, Center for Molecular Innovation and Drug Discovery, Evanston, Illinois, USA, Mark W. Holladay, Ambit Biosciences Corporation, Departments of Drug Discovery and Medicinal Chemistry, San Diego, California, USA
| The organic chemistry of drug design and drug action / / Richard B. Silverman, Northwestern University, Department of Chemistry, Department of Molecular Biosciences, Chemistry of Life Processes Institute, Center for Molecular Innovation and Drug Discovery, Evanston, Illinois, USA, Mark W. Holladay, Ambit Biosciences Corporation, Departments of Drug Discovery and Medicinal Chemistry, San Diego, California, USA |
| Autore | Silverman Richard B. |
| Edizione | [Third edition.] |
| Pubbl/distr/stampa | Amsterdam : , : Elsevier, , [2014] |
| Descrizione fisica | 1 online resource (xviii, 517 pages ) : illustrations (some color) |
| Disciplina | 615.1/9 |
| Soggetto topico |
Pharmaceutical chemistry
Bioorganic chemistry Molecular pharmacology Drugs - Design |
| Soggetto genere / forma | Electronic books. |
| ISBN | 0-12-382031-6 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Introduction -- Lead discovery and lead modification -- Receptors -- Enzymes -- Enzyme inhibition and inactivation -- Dna-interactive agents -- Drug resistance and drug synergism -- Drug metabolism -- Prodrugs and drug delivery systems. |
| Record Nr. | UNINA-9910464212803321 |
Silverman Richard B.
|
||
| Amsterdam : , : Elsevier, , [2014] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
The organic chemistry of drug design and drug action / / Richard B. Silverman, Mark W. Holladay
| The organic chemistry of drug design and drug action / / Richard B. Silverman, Mark W. Holladay |
| Autore | Silverman Richard B. |
| Edizione | [Third edition.] |
| Pubbl/distr/stampa | Amsterdam : , : Elsevier, , [2014] |
| Descrizione fisica | 1 online resource (xviii, 517 pages ) : illustrations (some color) |
| Disciplina | 615.1/9 |
| Soggetto topico |
Pharmaceutical chemistry
Bioorganic chemistry Molecular pharmacology Drugs - Design |
| ISBN | 0-12-382031-6 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Introduction -- Lead discovery and lead modification -- Receptors -- Enzymes -- Enzyme inhibition and inactivation -- Dna-interactive agents -- Drug resistance and drug synergism -- Drug metabolism -- Prodrugs and drug delivery systems. |
| Record Nr. | UNINA-9910789251703321 |
|
Silverman Richard B.
|
||
| Amsterdam : , : Elsevier, , [2014] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
The organic chemistry of drug design and drug action / / Richard B. Silverman, Mark W. Holladay
| The organic chemistry of drug design and drug action / / Richard B. Silverman, Mark W. Holladay |
| Autore | Silverman Richard B. |
| Edizione | [Third edition.] |
| Pubbl/distr/stampa | Amsterdam : , : Elsevier, , [2014] |
| Descrizione fisica | 1 online resource (xviii, 517 pages ) : illustrations (some color) |
| Disciplina | 615.1/9 |
| Soggetto topico |
Pharmaceutical chemistry
Bioorganic chemistry Molecular pharmacology Drugs - Design |
| ISBN | 0-12-382031-6 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Introduction -- Lead discovery and lead modification -- Receptors -- Enzymes -- Enzyme inhibition and inactivation -- Dna-interactive agents -- Drug resistance and drug synergism -- Drug metabolism -- Prodrugs and drug delivery systems. |
| Record Nr. | UNINA-9910829292503321 |
|
Silverman Richard B.
|
||
| Amsterdam : , : Elsevier, , [2014] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Peptide chemistry and drug design / / edited by Ben M. Dunn
| Peptide chemistry and drug design / / edited by Ben M. Dunn |
| Pubbl/distr/stampa | Hoboken, New Jersey : , : Wiley, , 2015 |
| Descrizione fisica | 1 online resource (337 pages) : illustrations (some color), charts |
| Disciplina | 615.1/9 |
| Soggetto topico |
Drugs - Design
Peptide drugs Peptides - Synthesis |
| ISBN |
1-118-99641-0
1-118-99530-9 1-118-99528-7 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910140478603321 |
| Hoboken, New Jersey : , : Wiley, , 2015 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Peptide chemistry and drug design / / edited by Ben M. Dunn
| Peptide chemistry and drug design / / edited by Ben M. Dunn |
| Pubbl/distr/stampa | Hoboken, New Jersey : , : Wiley, , 2015 |
| Descrizione fisica | 1 online resource (337 pages) : illustrations (some color), charts |
| Disciplina | 615.1/9 |
| Soggetto topico |
Drugs - Design
Peptide drugs Peptides - Synthesis |
| ISBN |
1-118-99641-0
1-118-99530-9 1-118-99528-7 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910828915703321 |
| Hoboken, New Jersey : , : Wiley, , 2015 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Peptide drug discovery and development [[electronic resource] ] : translational research in academia and industry / / edited by Miguel Castanho and Nuno C. Santos
| Peptide drug discovery and development [[electronic resource] ] : translational research in academia and industry / / edited by Miguel Castanho and Nuno C. Santos |
| Pubbl/distr/stampa | Weinheim, Germany, : Wiley-VCH, 2011 |
| Descrizione fisica | 1 online resource (392 p.) |
| Disciplina |
572.65
615.19 |
| Altri autori (Persone) |
CastanhoMiguel
SantosNuno C |
| Soggetto topico |
Peptide drugs
Drugs - Design Pharmacology |
| ISBN |
3-527-63674-9
1-283-30251-9 9786613302519 3-527-63673-0 3-527-63675-7 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Peptide Drug Discovery and Development: Translational Research in Academia and Industry; Contents; Preface; List of Contributors; Part I: The Academia - Market Bouncing of Peptide Drugs - Challenges and Strategies in Translational Research with Peptide Drugs; 1: Peptides as Leads for Drug Discovery; 1.1: Introduction; 1.2: Overview of Process for Transforming Peptides to Peptidomimetics; 1.3: HCMV Protease; 1.3.1: HCMV Protease: Identification and Characterization of Antiviral Inhibitors Targeting the Serine Protease Domain of the Human Cytomegalovirus (HCMV Protease)
1.3.2: Mapping Essential Elements of the Substrate Peptides and Determining Structures of Ligands Bound to HCMV1.3.3: Improving Peptide Activity to Allow SAR Studies; 1.3.4: Elucidation of the Binding Mode of the Optimized Peptidyl Segment; 1.3.5: Ligand Adaptations upon Binding; 1.3.6: Strategic Summary for HCMV Peptide Mimic Design Process; 1.4: HCV Protease; 1.4.1: HCV Protease as an Antiviral Target; 1.4.2: NS3 Serine Protease Possesses a Chymotrypsin-Like Fold; 1.4.3: Discovery of the Peptide DDIVPC as an Inhibitor of NS3 Protease 1.4.4: ''Sensemaking'' and Knowledge Building: Mapping of the Critical Binding Residues of the Peptide and Creation of an Inhibitor-Protease Model1.4.5: Knowledge Building: Monitoring Ligand Flexibility in the Free-State and Changes Upon Binding - P3 Rigidification; 1.4.6: N-Terminal Truncation and Improved P1, P2 and P5 Substituents; 1.4.7: Macrocyclization: Linking the Flexible P1 Side-Chain to P3; 1.4.8: HCV Protease Inhibitor BI00201335; 1.5: Herpes Simplex Virus; 1.5.1: Herpes Simplex Virus-Encoded Ribonucleotide Reductase Inhibitors; 1.6: Renin 1.6.1: Aspartyl Protease Renin as a Target1.7: HIV; 1.7.1: HIV Protease Inhibitors; 1.8: Conclusions; 2: Marketing Antimicrobial Peptides: A Critical Academic Point of View; 2.1: Introduction; 2.2: Basic Research: Antimicrobial Peptides; 2.3: Patents; 2.4: Potential Applications of AMPs; 2.5: Technology Transfer: Valorization, Licensing, or Spin-Off Creation; 2.6: Spin-Off Creation: An Academic Point of View; 3: Oral Peptide Drug Delivery: Strategies to Overcome Challenges; 3.1: Introduction; 3.2: Challenges Associated with Oral Peptide Delivery 3.2.1: Transport Pathways Across the Intestinal Epithelium3.2.2: Unfavorable Physicochemical Properties of Peptide Drugs; 3.2.2.1: Molecular Size, Hydrophilicity, and Physical Stability; 3.2.3: Physical Barriers of the Gastrointestinal Tract; 3.2.3.1: Transcellular Pathway; 3.2.3.2: Paracellular Pathway; 3.2.4: Biochemical Barriers of the Gastrointestinal Tract; 3.2.4.1: Luminal Enzymes; 3.2.4.2: Brush Border Membrane Bound Enzymes and Intracellular Enzymes; 3.2.5: Efflux Transport Systems; 3.2.6: Gastrointestinal Transit Time and Site-Specific Absorption 3.3: Strategies to Overcome the Barriers of the Gastrointestinal Tract |
| Record Nr. | UNINA-9910139579303321 |
| Weinheim, Germany, : Wiley-VCH, 2011 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Peptide drug discovery and development : translational research in academia and industry / / edited by Miguel Castanho and Nuno C. Santos
| Peptide drug discovery and development : translational research in academia and industry / / edited by Miguel Castanho and Nuno C. Santos |
| Pubbl/distr/stampa | Weinheim, Germany, : Wiley-VCH, 2011 |
| Descrizione fisica | 1 online resource (xix, 370 pages) : illustrations |
| Disciplina |
572.65
615.19 |
| Altri autori (Persone) |
CastanhoMiguel A. R. B
SantosNuno C |
| Soggetto topico |
Peptide drugs
Drugs - Design Pharmacology |
| ISBN |
3-527-63674-9
1-283-30251-9 9786613302519 3-527-63673-0 3-527-63675-7 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Peptide Drug Discovery and Development: Translational Research in Academia and Industry; Contents; Preface; List of Contributors; Part I: The Academia - Market Bouncing of Peptide Drugs - Challenges and Strategies in Translational Research with Peptide Drugs; 1: Peptides as Leads for Drug Discovery; 1.1: Introduction; 1.2: Overview of Process for Transforming Peptides to Peptidomimetics; 1.3: HCMV Protease; 1.3.1: HCMV Protease: Identification and Characterization of Antiviral Inhibitors Targeting the Serine Protease Domain of the Human Cytomegalovirus (HCMV Protease)
1.3.2: Mapping Essential Elements of the Substrate Peptides and Determining Structures of Ligands Bound to HCMV1.3.3: Improving Peptide Activity to Allow SAR Studies; 1.3.4: Elucidation of the Binding Mode of the Optimized Peptidyl Segment; 1.3.5: Ligand Adaptations upon Binding; 1.3.6: Strategic Summary for HCMV Peptide Mimic Design Process; 1.4: HCV Protease; 1.4.1: HCV Protease as an Antiviral Target; 1.4.2: NS3 Serine Protease Possesses a Chymotrypsin-Like Fold; 1.4.3: Discovery of the Peptide DDIVPC as an Inhibitor of NS3 Protease 1.4.4: ''Sensemaking'' and Knowledge Building: Mapping of the Critical Binding Residues of the Peptide and Creation of an Inhibitor-Protease Model1.4.5: Knowledge Building: Monitoring Ligand Flexibility in the Free-State and Changes Upon Binding - P3 Rigidification; 1.4.6: N-Terminal Truncation and Improved P1, P2 and P5 Substituents; 1.4.7: Macrocyclization: Linking the Flexible P1 Side-Chain to P3; 1.4.8: HCV Protease Inhibitor BI00201335; 1.5: Herpes Simplex Virus; 1.5.1: Herpes Simplex Virus-Encoded Ribonucleotide Reductase Inhibitors; 1.6: Renin 1.6.1: Aspartyl Protease Renin as a Target1.7: HIV; 1.7.1: HIV Protease Inhibitors; 1.8: Conclusions; 2: Marketing Antimicrobial Peptides: A Critical Academic Point of View; 2.1: Introduction; 2.2: Basic Research: Antimicrobial Peptides; 2.3: Patents; 2.4: Potential Applications of AMPs; 2.5: Technology Transfer: Valorization, Licensing, or Spin-Off Creation; 2.6: Spin-Off Creation: An Academic Point of View; 3: Oral Peptide Drug Delivery: Strategies to Overcome Challenges; 3.1: Introduction; 3.2: Challenges Associated with Oral Peptide Delivery 3.2.1: Transport Pathways Across the Intestinal Epithelium3.2.2: Unfavorable Physicochemical Properties of Peptide Drugs; 3.2.2.1: Molecular Size, Hydrophilicity, and Physical Stability; 3.2.3: Physical Barriers of the Gastrointestinal Tract; 3.2.3.1: Transcellular Pathway; 3.2.3.2: Paracellular Pathway; 3.2.4: Biochemical Barriers of the Gastrointestinal Tract; 3.2.4.1: Luminal Enzymes; 3.2.4.2: Brush Border Membrane Bound Enzymes and Intracellular Enzymes; 3.2.5: Efflux Transport Systems; 3.2.6: Gastrointestinal Transit Time and Site-Specific Absorption; 3.3: Strategies to Overcome the Barriers of the Gastrointestinal Tract |
| Record Nr. | UNINA-9910829074503321 |
| Weinheim, Germany, : Wiley-VCH, 2011 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Peptide Therapeutics : Fundamentals of Design, Development, and Delivery / / edited by Seetharama D. Jois
| Peptide Therapeutics : Fundamentals of Design, Development, and Delivery / / edited by Seetharama D. Jois |
| Edizione | [1st ed. 2022.] |
| Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2022 |
| Descrizione fisica | 1 online resource (321 pages) |
| Disciplina | 615.19 |
| Collana | AAPS Advances in the Pharmaceutical Sciences Series |
| Soggetto topico |
Pharmaceutical chemistry
Drug delivery systems Drugs - Design Pharmacology Pharmacy Proteins - Synthesis Pharmaceutics Drug Delivery Structure-Based Drug Design Protein Synthesis and Translation Medicaments peptídics Química farmacèutica |
| Soggetto genere / forma | Llibres electrònics |
| ISBN |
9783031045448
9783031045431 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Basic Concepts of Design of Peptide based Therapeutics -- Computational Methods in Peptide Based Drug Design -- Synthesis, Purification, and Characterization of Linear and Cyclic Peptides -- Large Scale Synthesis of Peptides, Manufacturing Peptide Therapeutics -- Stability of Peptides -- Peptide Delivery Systems -- Liposomes and Nanoparticle Formulations for Peptide Delivery -- Delivery of Peptides Across the Blood-brain Barrier (BBB) -- Peptide Therapeutics Regulatory Considerations. |
| Record Nr. | UNINA-9910616399103321 |
| Cham : , : Springer International Publishing : , : Imprint : Springer, , 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Soggetto topico
-
Drugs - Design
(283)
- Pharmaceutical chemistry (86)
- Drug development (61)
- Drug Design (35)
- Drug delivery systems (16)