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Applications of high-resolution mass spectrometry in drug discovery and development / / editor, Lekha Sleno
| Applications of high-resolution mass spectrometry in drug discovery and development / / editor, Lekha Sleno |
| Pubbl/distr/stampa | London, England : , : Future Science Ltd, , 2014 |
| Descrizione fisica | 1 online resource (174 pages) : illustrations (some color), graphs |
| Disciplina | 615.1901 |
| Collana | Future Science |
| Soggetto topico |
Drugs - Analysis
Drug development Mass spectrometry |
| ISBN |
1-909453-54-4
1-909453-55-2 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910789326903321 |
| London, England : , : Future Science Ltd, , 2014 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Applications of high-resolution mass spectrometry in drug discovery and development / / editor, Lekha Sleno
| Applications of high-resolution mass spectrometry in drug discovery and development / / editor, Lekha Sleno |
| Pubbl/distr/stampa | London, England : , : Future Science Ltd, , 2014 |
| Descrizione fisica | 1 online resource (174 pages) : illustrations (some color), graphs |
| Disciplina | 615.1901 |
| Collana | Future Science |
| Soggetto topico |
Drugs - Analysis
Drug development Mass spectrometry |
| ISBN |
1-909453-54-4
1-909453-55-2 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910809224603321 |
| London, England : , : Future Science Ltd, , 2014 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Bioanalysis
| Bioanalysis |
| Pubbl/distr/stampa | London, : Future Science, 2009- |
| Descrizione fisica | 1 online resource |
| Disciplina | 615.19005 |
| Soggetto topico |
Drugs - Analysis
Chemistry Techniques, Analytical - methods Pharmaceutical Preparations - analysis Technology, Pharmaceutical |
| Soggetto genere / forma | Periodicals. |
| ISSN | 1757-6199 |
| Formato | Materiale a stampa |
| Livello bibliografico | Periodico |
| Lingua di pubblicazione | eng |
| Record Nr. | UNISA-996204905403316 |
| London, : Future Science, 2009- | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. di Salerno | ||
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Bioanalysis
| Bioanalysis |
| Pubbl/distr/stampa | London, : Future Science, 2009- |
| Descrizione fisica | 1 online resource |
| Disciplina | 615.19005 |
| Soggetto topico |
Drugs - Analysis
Chemistry Techniques, Analytical - methods Pharmaceutical Preparations - analysis Technology, Pharmaceutical |
| Soggetto genere / forma | Periodicals. |
| ISSN | 1757-6199 |
| Formato | Materiale a stampa |
| Livello bibliografico | Periodico |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910146094503321 |
| London, : Future Science, 2009- | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Bioanalysis for service users / / foreword by Anne-Francoise Aubry, Jim X. Shen
| Bioanalysis for service users / / foreword by Anne-Francoise Aubry, Jim X. Shen |
| Pubbl/distr/stampa | London, England : , : Future Science Ltd, , 2013 |
| Descrizione fisica | 1 online resource (117 pages) : illustrations (some color), graphs, tables |
| Disciplina | 615.1901 |
| Collana | Future Science |
| Soggetto topico |
Drugs - Analysis
Biomolecules - Analysis Drug development |
| ISBN | 1-909453-76-5 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | egy |
| Record Nr. | UNINA-9910789328103321 |
| London, England : , : Future Science Ltd, , 2013 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Bioanalysis for service users / / foreword by Anne-Francoise Aubry, Jim X. Shen
| Bioanalysis for service users / / foreword by Anne-Francoise Aubry, Jim X. Shen |
| Pubbl/distr/stampa | London, England : , : Future Science Ltd, , 2013 |
| Descrizione fisica | 1 online resource (117 pages) : illustrations (some color), graphs, tables |
| Disciplina | 615.1901 |
| Collana | Future Science |
| Soggetto topico |
Drugs - Analysis
Biomolecules - Analysis Drug development |
| ISBN | 1-909453-76-5 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | egy |
| Record Nr. | UNINA-9910809224803321 |
| London, England : , : Future Science Ltd, , 2013 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Biomedical chromatography [[electronic resource] /] / John T. Elwood, editor
| Biomedical chromatography [[electronic resource] /] / John T. Elwood, editor |
| Pubbl/distr/stampa | New York, : Nova Science, c2010 |
| Descrizione fisica | 1 online resource (190 p.) |
| Disciplina | 615/.1901 |
| Altri autori (Persone) | ElwoodJohn T |
| Collana | Chemical engineering methods and technology |
| Soggetto topico |
Drugs - Analysis
Chromatographic analysis Pharmaceutical chemistry |
| Soggetto genere / forma | Electronic books. |
| ISBN | 1-61668-470-4 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Bioanalysis in drug discovery and development : focus on pharmacokinetic studies / Gilberto Alves, Ana Fortuna, Amílcar Falcão -- Characterization of drug-plasmatic protein interactions by microseparation techniques / Maria Amparo Martínez-Gómez ... [et al.] -- Statistical approaches for bioequivalence of highly variable drugs and drug products / Alionka Citlali P. Angeles-Moreno, Gabriel Marcelín-Jiménez, Salvador Zamora-Muñoz -- New strategies of sample preparation in the analysis of pharmaceuticals and their determination using high performance liquid chromatography / Zoraida Sosa-Ferrera ... [et al.] -- Analysis of catecholamines with peroxyoxalate chemiluminescence reaction detection / Makoto Tsunoda -- Photoproducts of naproxen in alcoholic solvents / Hsin-Tsung Ho ... [et al.]. |
| Record Nr. | UNINA-9910465675903321 |
| New York, : Nova Science, c2010 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Biomedical chromatography / / John T. Elwood, editor
| Biomedical chromatography / / John T. Elwood, editor |
| Pubbl/distr/stampa | New York : , : Nova Science, , 2010 |
| Descrizione fisica | 1 online resource (190 pages) |
| Disciplina | 615/.1901 |
| Altri autori (Persone) | ElwoodJohn T |
| Collana | Chemical engineering methods and technology |
| Soggetto topico |
Drugs - Analysis
Chromatographic analysis Pharmaceutical chemistry |
| ISBN | 1-61668-470-4 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Bioanalysis in drug discovery and development : focus on pharmacokinetic studies / Gilberto Alves, Ana Fortuna, Amílcar Falcão -- Characterization of drug-plasmatic protein interactions by microseparation techniques / Maria Amparo Martínez-Gómez ... [et al.] -- Statistical approaches for bioequivalence of highly variable drugs and drug products / Alionka Citlali P. Angeles-Moreno, Gabriel Marcelín-Jiménez, Salvador Zamora-Muñoz -- New strategies of sample preparation in the analysis of pharmaceuticals and their determination using high performance liquid chromatography / Zoraida Sosa-Ferrera ... [et al.] -- Analysis of catecholamines with peroxyoxalate chemiluminescence reaction detection / Makoto Tsunoda -- Photoproducts of naproxen in alcoholic solvents / Hsin-Tsung Ho ... [et al.]. |
| Record Nr. | UNINA-9910791768403321 |
| New York : , : Nova Science, , 2010 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Biomedical chromatography / / John T. Elwood, editor
| Biomedical chromatography / / John T. Elwood, editor |
| Edizione | [1st ed.] |
| Pubbl/distr/stampa | New York : , : Nova Science, , 2010 |
| Descrizione fisica | 1 online resource (190 pages) |
| Disciplina | 615/.1901 |
| Altri autori (Persone) | ElwoodJohn T |
| Collana | Chemical engineering methods and technology |
| Soggetto topico |
Drugs - Analysis
Chromatographic analysis Pharmaceutical chemistry |
| ISBN | 1-61668-470-4 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Bioanalysis in drug discovery and development : focus on pharmacokinetic studies / Gilberto Alves, Ana Fortuna, Amílcar Falcão -- Characterization of drug-plasmatic protein interactions by microseparation techniques / Maria Amparo Martínez-Gómez ... [et al.] -- Statistical approaches for bioequivalence of highly variable drugs and drug products / Alionka Citlali P. Angeles-Moreno, Gabriel Marcelín-Jiménez, Salvador Zamora-Muñoz -- New strategies of sample preparation in the analysis of pharmaceuticals and their determination using high performance liquid chromatography / Zoraida Sosa-Ferrera ... [et al.] -- Analysis of catecholamines with peroxyoxalate chemiluminescence reaction detection / Makoto Tsunoda -- Photoproducts of naproxen in alcoholic solvents / Hsin-Tsung Ho ... [et al.]. |
| Record Nr. | UNINA-9910809837403321 |
| New York : , : Nova Science, , 2010 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Characterization of impurities and degradants using mass spectrometry / / edited by Birendra N. Pramanik, Mike S. Lee, Guodong Chen
| Characterization of impurities and degradants using mass spectrometry / / edited by Birendra N. Pramanik, Mike S. Lee, Guodong Chen |
| Pubbl/distr/stampa | Hoboken : , : Wiley, , 2011 |
| Descrizione fisica | 1 online resource (xxii, 462 pages) : illustrations |
| Disciplina |
615.1
615/.1 |
| Altri autori (Persone) |
PramanikBirendra N. <1944->
LeeMike S. <1960-> ChenGuodong |
| Collana | Wiley Series on Pharmaceutical Science and Biotechnology: Practices, Applications and Methods |
| Soggetto topico |
Drugs - Analysis
Drugs - Spectra Mass spectrometry Contamination (Technology) Public Health Chemistry Techniques, Analytical Investigative Techniques Environment and Public Health Health Care Pharmaceutical Preparations Mass Spectrometry Drug Contamination Health & Biological Sciences Pharmacy, Therapeutics, & Pharmacology |
| ISBN |
1-283-23943-4
9786613239433 0-470-92136-6 0-470-92137-4 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
CHARACTERIZATION OF IMPURITIES AND DEGRADANTS USING MASS SPECTROMETRY; CONTENTS; PREFACE; CONTRIBUTORS; ACRONYMS; PART I: METHODOLOGY; 1. Introduction to Mass Spectrometry; 1.1. History; 1.1.1. Atomic Physics; 1.1.2. Early Applications; 1.1.3. Organic Structural Analysis; 1.1.4. The Biological Mass Spectrometry Revolution; 1.2. Ionization Methods; 1.3. Mass Spectrometer Types; 1.3.1. Magnetic Sector Mass Spectrometers; 1.3.2. Quadrupole Mass Filter and Quadrupole Ion Trap Mass Spectrometers; 1.3.3. Time-of-Flight Mass Spectrometers
1.3.4. Fourier Transform Ion Cyclotron Resonance Mass Spectrometers; 1.3.5. Orbitrap Mass Spectrometers; 1.4. Tandem Mass Spectrometry; 1.4.1. Ion Isolation; 1.4.2. Ion-Molecule Collisions and Collision-Induced Dissociation; 1.4.3. Electron Capture Dissociation and Electron Transfer Dissociation; 1.5. Separation Techniques Coupled to Mass Spectrometry; 1.5.1. Gas Chromatography-Mass Spectrometry; 1.5.2. Liquid Chromatography-Mass Spectrometry; 1.5.3. Capillary Electrophoresis-Mass Spectrometry; 1.5.4. Ion Mobility Spectrometry-Mass Spectrometry; 1.6. Prospects for Mass Spectrometry; References 2. LC Method Development and Strategies; 2.1. Introduction; 2.2. Column, pH, and Solvent Screening; 2.2.1. Resolution: Goal of Separation; 2.2.2. Screening: Systematic Approach to Seeking Selectivity; 2.2.3. Screening Instrumentation and Controlling Software; 2.3. Gradient and Temperature Optimization; 2.4. Orthogonal Screening; 2.4.1. Method Orthogonality; 2.4.2. Selection of Orthogonal Methods; 2.4.3. Impurity Orthogonal Screening; 2.5. High-Efficiency Separation; 2.6. Conclusions; References 3. Rapid Analysis of Drug-Related Substances using Desorption Electrospray Ionization and Direct Analysis in Real Time Ionization Mass Spectrometry; 3.1. Introduction; 3.2. Ionization Apparatus, Mechanisms, and General Performance; 3.2.1. Desorption Electrospray Ionization (DESI); 3.2.2. Direct Analysis in Real Time (DART); 3.3. Drug Analysis in Biological Matrices using DESI and DART; 3.3.1. DESI Application; 3.3.2. DART Application; 3.4. High-Throughput Analysis; 3.5. Chemical Imaging and Profiling; 3.6. Future Perspectives; References; 4. Orbitrap High-Resolution Applications 4.1. Historical Anecdote; 4.2. General Description of Orbitrap Operating Principles; 4.3. The Orbitrap is a "Fourier Transform" Device; 4.4. Performing Experiments in Trapping Devices; 4.4.1. "Raw" HPLC Data Look Like Infusion Data; 4.4.2. How Much Mass Resolution Should Be Used During HPLC; 4.5. Determining Elemental Compositions of "Unknowns" Using an Orbitrap; 4.6. Orbitrap Figures of Merit in Mass Measurement; 4.6.1. Accuracy; 4.6.2. Precision; 4.6.3. Discussion; 4.7. HPLC Orbitrap MS: Accurate Mass Demonstration and Differentiation of Small Molecule Formulas Very Proximate in Mass/Charge Ratio Space |
| Record Nr. | UNINA-9910132377503321 |
| Hoboken : , : Wiley, , 2011 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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