Autore	Kar Ashutosh
Edizione	[2nd ed.]
Pubbl/distr/stampa	New Delhi, : New Age International (P) Ltd., Publishers, 2005
Descrizione fisica	1 online resource (554 p.)
Disciplina	600
Soggetto topico	Drugs - Analysis Drugs - Testing
Soggetto genere / forma	Electronic books.
ISBN	1-282-12901-5 9786612129018 81-224-2718-9
Formato	Materiale a stampa
Livello bibliografico	Monografia
Lingua di pubblicazione	eng
Nota di contenuto	pt. 1. General aspects -- pt. 2. Chemical methods -- pt. 3. Electrochemical methods -- pt. 4. Optical methods -- pt. 5. Assay methods based on separation techniques -- pt. 6. Miscellaneous methods.
Record Nr.	UNINA-9910454705003321

Pubbl/distr/stampa	Weinheim, : Wiley-VCH, c2005
Descrizione fisica	1 online resource (488 p.)
Disciplina	615.1901
Altri autori (Persone)	Schmidt-TraubH
Soggetto topico	Chromatographic analysis Drugs - Analysis
Soggetto genere / forma	Electronic books.
ISBN	1-280-52078-7 9786610520787 3-527-60348-4 3-527-60590-8
Classificazione	540 CHE 232f CIT 060f CIT 220f VG 7200
Formato	Materiale a stampa
Livello bibliografico	Monografia
Lingua di pubblicazione	eng
Nota di contenuto	Preparative Chromatography; Contents; Preface; List of Contributors; Notation; List of Abbreviations; 1 Introduction; 2 Fundamentals and General Terminology; 3 Columns, Packings and Stationary Phases; 4 Selection of Chromatographic Systems; 5 Process Concepts; 6 Modeling and Determination of Model Parameters; 7 Model Based Design and Optimization; 8 Chromatographic Reactors; 9 Advanced Control of Simulated Moving Bed Processes; Outlook; References; Appendix A; Appendix B: Data of Test Systems; Index
Record Nr.	UNINA-9910144007103321

Pubbl/distr/stampa	Weinheim, Germany, : Wiley-VCH, 2011
Descrizione fisica	1 online resource (371 p.)
Disciplina	004.3 660.28
Altri autori (Persone)	HousonI. N (Ian N.)
Soggetto topico	Drugs - Design Pharmaceutical microbiology Drugs - Analysis
Soggetto genere / forma	Electronic books.
ISBN	3-527-65036-9 1-283-28330-1 9786613283306 3-527-63715-X 3-527-63716-8 3-527-63714-1
Formato	Materiale a stampa
Livello bibliografico	Monografia
Lingua di pubblicazione	eng
Nota di contenuto	Process Understanding; Contents; Preface; List of Contributors; 1 Quality by Design; 1.1 History; 1.2 Defining Product Design Requirements and Critical Quality Attributes; 1.3 The Role of Quality Risk Management in QbD; 1.4 Design Space and Control Strategy; 1.5 Quality Systems; References; 2 Route and Process Selection; 2.1 Introduction; 2.2 Route Evaluation; 2.3 Factors to Consider; 2.3.1 Timing; 2.3.2 Costs; 2.3.2.1 Removal of a Chromatography Step; 2.3.3 Safety, Health, and Environment (SHE); 2.3.3.1 Safer Processes; 2.3.3.2 Green Chemistry; 2.3.4 Legal; 2.3.5 Other Considerations 2.3.5.1 Throughput2.3.5.2 Solvents; 2.3.5.3 Raw Materials; 2.3.5.4 Intermediates; 2.4 Route Selection; 2.4.1 Sildenafil; 2.5 Process Selection; 2.5.1 Pregabalin; 2.5.2 NK1 Receptor Antagonist; 2.5.3 Data; 2.6 Summary; References; 3 Critical Stages of Safety Assessment in Process Design and Scale-Up; 3.1 Reaction Safety Concepts; 3.1.1 What Is the Hazard?; 3.1.2 The Critical Effects of Scale-Up on Thermal Behavior; 3.1.3 Safety Features of a Reaction; 3.1.4 Stages of Safety Assessment; 3.2 Pre-Laboratory Safety Studies; 3.2.1 Predicting Reaction Safety Characteristics 3.2.2 Selecting Inherently Safer Processing Conditions3.3 The Synergies of Safety and Optimization - Together; 3.3.1 Testing of Potentially Explosive Compounds; 3.3.2 Thermal Stability Assessment; 3.3.3 Reaction Thermodynamic, Kinetic, and Gas-Generation Quantification; 3.3.4 Developing Fault-Tolerant Processes - by Design; 3.4 Establishing a Reliable Basis of Safety for Scale-Up; 3.4.1 Hazardous Scenario Identification; 3.4.2 Determining the Consequences of Hazardous Scenarios; 3.4.3 Experimental Simulation - Adiabatic Calorimetry; 3.4.4 Specify and Implement Safety Measures 3.4.5 Large-Scale Production3.5 Flammability Hazards; 3.5.1 Assessing Pilot-Scale Flammability Hazards; 3.6 Summary; References; 4 Understanding the Reaction; 4.1 Introduction; 4.2 Process Complexity; 4.2.1 Number of Phases; 4.2.2 Physical and Dynamic Complexity; 4.2.2.1 Length Scales; 4.2.2.2 Time; 4.2.2.3 Solubility; 4.2.2.4 Density; 4.2.2.5 Rheology; 4.2.2.6 Heat Transfer; 4.2.2.7 Mass Transfer/Interfacial Area; 4.2.2.8 Mixing Time; 4.2.3 Chemical Complexity; 4.3 Topics for Data Acquisition; 4.4 Reaction Profiles; 4.5 Reaction Pictures; 4.6 Ionic Equilibria and Reaction Selectivity 4.6.1 Nitration4.6.2 Acylation; 4.6.3 Association Equilibria - Lithium Diethylamide (LDA); 4.7 Kinetics; 4.7.1 Order of Reaction; 4.8 Catalyzed Processes; 4.9 The Rate-Determining Step; 4.10 Mixing in Chemical Reactors; 4.11 Mixing Theory; 4.11.1 Mixing Regimes; 4.11.2 Micromixing; 4.11.3 Macromixing; 4.11.4 Mesomixing; 4.11.5 Determining Mixing Sensitivity in the Laboratory; 4.11.6 Comments on Scalability of Mixing; 4.12 Multiphase Processes; 4.13 Mass Transfer Theory; 4.13.1 Effect of Mass Transfer on Chemical Reaction Rates; 4.13.1.1 Chemical Rate-Limited Reaction 4.13.1.2 Mass Transfer Rate-Limited Reaction
Record Nr.	UNINA-9910131029403321

Pubbl/distr/stampa	[S.l.], : Bentham e Books, [2010]
Descrizione fisica	1 online resource (160 p.)
Disciplina	600
Altri autori (Persone)	TzanavarasParaskevas D ZacharisConstantinos K
Soggetto topico	Drugs - Analysis Drug monitoring
Soggetto genere / forma	Electronic books.
ISBN	1-60805-190-0
Formato	Materiale a stampa
Livello bibliografico	Monografia
Lingua di pubblicazione	eng
Nota di contenuto	01 Title.pdf; 02 Cover Page; 03 eBooks End User License Agreement-Website; 05 Forward; 06 Preface; 07 List of contributors; 08 Chapter 1 _Andrade_; 09 Chapter 2 _Loukas_ revised; 10 Chapter 3 _Mauri_ revised; 11 Chapter 4 _Xu_ revised; 12 Chapter 5 _O'Kennedy_; 13 Chapter 6 _Kauffmann_; 14 Chapter 7 _Samanidou_ revised; 15 Chapter 8 _Starek_ revised; 16 Chapter 9 _Tan_ revised; 17 Chapter 10 _Li_; 18 INDEX
Record Nr.	UNINA-9910458887603321