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The challenges of antibiotic resistance in the development of new therapeutics / / Oliveira Manuela, Isa D. Serrano, editors ; contributors Amelia Fernandes [and twenty five others]
The challenges of antibiotic resistance in the development of new therapeutics / / Oliveira Manuela, Isa D. Serrano, editors ; contributors Amelia Fernandes [and twenty five others]
Pubbl/distr/stampa Sharjah, United Arab Emirates : , : Bentham Science Publishers Ltd., , [2015]
Descrizione fisica 1 online resource (279 p.)
Disciplina 616.9041
Collana Frontiers in Antimicrobial Agents
Soggetto topico Drug resistance in microorganisms
ISBN 1-68108-140-7
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto CONTENTS; FOREWORD ; PREFACE ; List of Contributors ; Introduction ; INTRODUCTION; CONFLICT OF INTEREST; ACKNOWLEDGEMENTS; REFERENCES; Bacteriophages as Antibacterial Agents: Why are We Facing an Antibiotic Crisis and How Could Bacteriophages be of Help? ; 1. INTRODUCTION; 2. WHY ARE WE FACING AN ANTIBIOTIC (AB) CRISIS? ; 3. HOW TO RESOLVE THIS ANTIBIOTIC CRISIS? ; 4. BACTERIOPHAGES OR IN SHORT 'PHAGES'; 5. BACTERIOPHAGE THERAPY OR PHAGE THERAPY; 6. EXPERIMENTAL PHAGE THERAPY; 7. SAFETY ISSUES; 8. IN FACT WE LIVE IN AN "OCEAN" OF BACTERIOPHAGES; 9. SAFETY REQUIREMENTS FOR PHAGE THERAPY
10. THE POTENTIAL ADVANTAGES OF PHAGE THERAPY VERSUS ANTIBIOTICS11. PHAGE THERAPY IN PUBLIC HEALTH; 12. WHY PHAGE THERAPY IS NOT YET IMPLEMENTED?; CONCLUSIONS AND PERSPECTIVES; CONFLICT OF INTEREST; ACKNOWLEDGEMENTS; REFERENCES; Antimicrobial Peptides ; INTRODUCTION; 1. WHAT ARE ANTIMICROBIAL PEPTIDES (AMPS); 1.1. Mode of Action; 1.2. Immune System; 1.3. Resistance; 2. CHRONOLOGY OF AMPS DISCOVERY - A BRIEF HISTORY; 2.1. Classification of AMPs; 2.1.1. Biological Source; 2.1.2. Biological Functions; 2.1.3. Biosynthesis; 2.1.4. Molecular Properties; 2.1.5. Molecular Targets
2.1.6. Three-Dimensional (3D) Structure2.2. Currently Active AMPs Databases; 3. THERAPEUTIC APPLICATIONS OF AMPS; 3.1. Anticancer AMPs; 3.2. Antiviral AMPs; 3.3. Anti-parasitic AMPs; 3.4. New Generation of AMPs; CONCLUDING REMARKS; CONFLICT OF INTEREST; ACKNOWLEDGEMENTS; REFERENCES; Probiotics: Ways of Action and Beneficial Effects ; 1. INTRODUCTION; 2. SELECTION OF PROBIOTICS; 3. COMMERCIALLY IMPORTANT PROBIOTICS; 4. MECHANISMS OF ACTION OF PROBIOTICS; 4.1. Immunomodulation; 4.2. Direct Effects on Other Microorganisms; 5. BENEFICIAL HEALTH EFFECTS OF PROBIOTICS
5.1. Alleviation of Lactose Intolerance5.2. Effect on Helicobacter Pylori Eradication ; 5.3. Anti-carcinogenic Effect; 5.4. Cholesterol-lowering Effects; 5.5. Allergy and Atopic Dermatitis; 5.6. Inflammatory Diseases and Bowel Syndromes ; CONCLUSION; CONFLICT OF INTEREST; ACKNOWLEDGEMENTS; REFERENCES; Immunotherapy ; 1. BACTERIAL INFECTIVITY, IMMUNE RESPONSE AND MULTIRESISTANT INFECTIONS : NEW PERSPECTIVES; 1.1. Introduction; 1.2. Host Resistance; 1.3. Bacterial Strategies for Evading, Surviving Host Defense Systems and Create Infection; 2. IMMUNOTHERAPY; 2.1. Introduction
2.2. Applications of Immunotherapy2.3. Passive Immunotherapy; 2.4. Passive Immunotherapy: Antibodies ; 2.5. Passive Immunotherapy: Adoptive T-cell Transfer; 2.6. Passive Immunotherapy: Immunomodulators; 2.7. Growth Factors; 2.7.1. Filgastrim ; 2.7.2. Sargramostim ; 2.7.3. Erythropoietin (EPO) ; 2.7.4. Insulin-like Growth Factor-1 (IGF-1); 2.8. Interleukins; 2.8.1. Interleukin 2; 2.8.2. Interleukin-8; 2.9. Interferons; 2.9.1. Human Interferon Alpha (HuIFN- α); 2.9.2. Recombinant-Feline Interferon Omega (rFeIFN- ω) ; 2.10. Nonspecific Immunostimulants; 2.10.1. Staphylococcal Protein A (SPA)
2.10.2. Propionibacterium Acnes
Record Nr. UNINA-9910812819103321
Sharjah, United Arab Emirates : , : Bentham Science Publishers Ltd., , [2015]
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Ciba Foundation Symposium on Drug Resistance in Micro-Organisms [[electronic resource] ] : mechanisms of development. / / editors for the Ciba Foundation, G.E.W. Wolstenholme and Cecilia M. O'Connor
Ciba Foundation Symposium on Drug Resistance in Micro-Organisms [[electronic resource] ] : mechanisms of development. / / editors for the Ciba Foundation, G.E.W. Wolstenholme and Cecilia M. O'Connor
Pubbl/distr/stampa Boston, : Little, Brown, [1957]
Descrizione fisica 1 online resource (384 p.)
Disciplina 600
Altri autori (Persone) WolstenholmeG. E. W (Gordon Ethelbert Ward)
O'ConnorCecilia M <1927-> (Cecilia Mary)
Collana Ciba Foundation symposium
Soggetto topico Drug resistance in microorganisms
Soggetto genere / forma Electronic books.
ISBN 1-280-76861-4
9786613679383
0-470-71905-2
0-470-71652-5
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto DRUG RESISTANCE IN MICRO-ORGANISMS; CONTENTS; Chairman's opening remarks; Aspects of the problem of drug resistance in bacteria; Discussion; Indirect selection and origin of resistance; Discussion; Genetic aspects of drug resistance; Discussion; Inheritance in single bacterial cells; Discussion; Penicillin-induced resistance to penicillin in cultures of Bacillus cereus; Discussion; Directed hereditary changes of fermentative properties of yeast by a specific substrate; Discussion; Multiple mechanisms of acquired drug resistance; Discussion
Physiological (phenotypic) mechanisms responsible for drug resistanceDiscussion; Genetic and metabolic mechanisms underlying multiple levels of sulphonamide resistance in pneumococci; Discussion; The phenotypic expression of genes determining various types of drug resistance following their inheritance by sensitive bacteria; Discussion; Specific polyhydroxy compounds as cofactors of enzymic adaptation and its inheritance; Discussion; Development of resistance to streptomycin in Serratia marcescens; Discussion
Distribution of drug-resistant individuals in cultures of Mycobacterium tuberculosisDiscussion; Physiological adaptation of bacteria to antibiotics; Discussion; Drug resistance of staphylococci with special reference to penicillinase production; Discussion; On the identification of genetic and non-genetic variation in bacteria; Discussion; The reactions of the mutagenic alkylating agents with proteins and nucleic acids; Discussion; Genetics of two different mechanisms of resistance to colicins: resistance by loss of specific receptors and im- munity by transfer of colicinogenic factors
DiscussionGeneral Discussion; Chairman's closing remarks
Record Nr. UNINA-9910144680603321
Boston, : Little, Brown, [1957]
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Ciba Foundation Symposium on Drug Resistance in Micro-Organisms [[electronic resource] ] : mechanisms of development. / / editors for the Ciba Foundation, G.E.W. Wolstenholme and Cecilia M. O'Connor
Ciba Foundation Symposium on Drug Resistance in Micro-Organisms [[electronic resource] ] : mechanisms of development. / / editors for the Ciba Foundation, G.E.W. Wolstenholme and Cecilia M. O'Connor
Pubbl/distr/stampa Boston, : Little, Brown, [1957]
Descrizione fisica 1 online resource (384 p.)
Disciplina 600
Altri autori (Persone) WolstenholmeG. E. W (Gordon Ethelbert Ward)
O'ConnorCecilia M <1927-> (Cecilia Mary)
Collana Ciba Foundation symposium
Soggetto topico Drug resistance in microorganisms
ISBN 1-280-76861-4
9786613679383
0-470-71905-2
0-470-71652-5
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto DRUG RESISTANCE IN MICRO-ORGANISMS; CONTENTS; Chairman's opening remarks; Aspects of the problem of drug resistance in bacteria; Discussion; Indirect selection and origin of resistance; Discussion; Genetic aspects of drug resistance; Discussion; Inheritance in single bacterial cells; Discussion; Penicillin-induced resistance to penicillin in cultures of Bacillus cereus; Discussion; Directed hereditary changes of fermentative properties of yeast by a specific substrate; Discussion; Multiple mechanisms of acquired drug resistance; Discussion
Physiological (phenotypic) mechanisms responsible for drug resistanceDiscussion; Genetic and metabolic mechanisms underlying multiple levels of sulphonamide resistance in pneumococci; Discussion; The phenotypic expression of genes determining various types of drug resistance following their inheritance by sensitive bacteria; Discussion; Specific polyhydroxy compounds as cofactors of enzymic adaptation and its inheritance; Discussion; Development of resistance to streptomycin in Serratia marcescens; Discussion
Distribution of drug-resistant individuals in cultures of Mycobacterium tuberculosisDiscussion; Physiological adaptation of bacteria to antibiotics; Discussion; Drug resistance of staphylococci with special reference to penicillinase production; Discussion; On the identification of genetic and non-genetic variation in bacteria; Discussion; The reactions of the mutagenic alkylating agents with proteins and nucleic acids; Discussion; Genetics of two different mechanisms of resistance to colicins: resistance by loss of specific receptors and im- munity by transfer of colicinogenic factors
DiscussionGeneral Discussion; Chairman's closing remarks
Record Nr. UNINA-9910643378903321
Boston, : Little, Brown, [1957]
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Ciba Foundation Symposium on Drug Resistance in Micro-Organisms [[electronic resource] ] : mechanisms of development. / / editors for the Ciba Foundation, G.E.W. Wolstenholme and Cecilia M. O'Connor
Ciba Foundation Symposium on Drug Resistance in Micro-Organisms [[electronic resource] ] : mechanisms of development. / / editors for the Ciba Foundation, G.E.W. Wolstenholme and Cecilia M. O'Connor
Pubbl/distr/stampa Boston, : Little, Brown, [1957]
Descrizione fisica 1 online resource (384 p.)
Disciplina 600
Altri autori (Persone) WolstenholmeG. E. W (Gordon Ethelbert Ward)
O'ConnorCecilia M <1927-> (Cecilia Mary)
Collana Ciba Foundation symposium
Soggetto topico Drug resistance in microorganisms
ISBN 1-280-76861-4
9786613679383
0-470-71905-2
0-470-71652-5
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto DRUG RESISTANCE IN MICRO-ORGANISMS; CONTENTS; Chairman's opening remarks; Aspects of the problem of drug resistance in bacteria; Discussion; Indirect selection and origin of resistance; Discussion; Genetic aspects of drug resistance; Discussion; Inheritance in single bacterial cells; Discussion; Penicillin-induced resistance to penicillin in cultures of Bacillus cereus; Discussion; Directed hereditary changes of fermentative properties of yeast by a specific substrate; Discussion; Multiple mechanisms of acquired drug resistance; Discussion
Physiological (phenotypic) mechanisms responsible for drug resistanceDiscussion; Genetic and metabolic mechanisms underlying multiple levels of sulphonamide resistance in pneumococci; Discussion; The phenotypic expression of genes determining various types of drug resistance following their inheritance by sensitive bacteria; Discussion; Specific polyhydroxy compounds as cofactors of enzymic adaptation and its inheritance; Discussion; Development of resistance to streptomycin in Serratia marcescens; Discussion
Distribution of drug-resistant individuals in cultures of Mycobacterium tuberculosisDiscussion; Physiological adaptation of bacteria to antibiotics; Discussion; Drug resistance of staphylococci with special reference to penicillinase production; Discussion; On the identification of genetic and non-genetic variation in bacteria; Discussion; The reactions of the mutagenic alkylating agents with proteins and nucleic acids; Discussion; Genetics of two different mechanisms of resistance to colicins: resistance by loss of specific receptors and im- munity by transfer of colicinogenic factors
DiscussionGeneral Discussion; Chairman's closing remarks
Record Nr. UNISA-996201245303316
Boston, : Little, Brown, [1957]
Materiale a stampa
Lo trovi qui: Univ. di Salerno
Opac: Controlla la disponibilità qui
Ciba Foundation Symposium on Drug Resistance in Micro-Organisms [[electronic resource] ] : mechanisms of development. / / editors for the Ciba Foundation, G.E.W. Wolstenholme and Cecilia M. O'Connor
Ciba Foundation Symposium on Drug Resistance in Micro-Organisms [[electronic resource] ] : mechanisms of development. / / editors for the Ciba Foundation, G.E.W. Wolstenholme and Cecilia M. O'Connor
Pubbl/distr/stampa Boston, : Little, Brown, [1957]
Descrizione fisica 1 online resource (384 p.)
Disciplina 600
Altri autori (Persone) WolstenholmeG. E. W (Gordon Ethelbert Ward)
O'ConnorCecilia M <1927-> (Cecilia Mary)
Collana Ciba Foundation symposium
Soggetto topico Drug resistance in microorganisms
ISBN 1-280-76861-4
9786613679383
0-470-71905-2
0-470-71652-5
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto DRUG RESISTANCE IN MICRO-ORGANISMS; CONTENTS; Chairman's opening remarks; Aspects of the problem of drug resistance in bacteria; Discussion; Indirect selection and origin of resistance; Discussion; Genetic aspects of drug resistance; Discussion; Inheritance in single bacterial cells; Discussion; Penicillin-induced resistance to penicillin in cultures of Bacillus cereus; Discussion; Directed hereditary changes of fermentative properties of yeast by a specific substrate; Discussion; Multiple mechanisms of acquired drug resistance; Discussion
Physiological (phenotypic) mechanisms responsible for drug resistanceDiscussion; Genetic and metabolic mechanisms underlying multiple levels of sulphonamide resistance in pneumococci; Discussion; The phenotypic expression of genes determining various types of drug resistance following their inheritance by sensitive bacteria; Discussion; Specific polyhydroxy compounds as cofactors of enzymic adaptation and its inheritance; Discussion; Development of resistance to streptomycin in Serratia marcescens; Discussion
Distribution of drug-resistant individuals in cultures of Mycobacterium tuberculosisDiscussion; Physiological adaptation of bacteria to antibiotics; Discussion; Drug resistance of staphylococci with special reference to penicillinase production; Discussion; On the identification of genetic and non-genetic variation in bacteria; Discussion; The reactions of the mutagenic alkylating agents with proteins and nucleic acids; Discussion; Genetics of two different mechanisms of resistance to colicins: resistance by loss of specific receptors and im- munity by transfer of colicinogenic factors
DiscussionGeneral Discussion; Chairman's closing remarks
Record Nr. UNINA-9910830591303321
Boston, : Little, Brown, [1957]
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Ciba Foundation Symposium on Drug Resistance in Micro-Organisms [[electronic resource] ] : mechanisms of development. / / editors for the Ciba Foundation, G.E.W. Wolstenholme and Cecilia M. O'Connor
Ciba Foundation Symposium on Drug Resistance in Micro-Organisms [[electronic resource] ] : mechanisms of development. / / editors for the Ciba Foundation, G.E.W. Wolstenholme and Cecilia M. O'Connor
Pubbl/distr/stampa Boston, : Little, Brown, [1957]
Descrizione fisica 1 online resource (384 p.)
Disciplina 600
Altri autori (Persone) WolstenholmeG. E. W (Gordon Ethelbert Ward)
O'ConnorCecilia M <1927-> (Cecilia Mary)
Collana Ciba Foundation symposium
Soggetto topico Drug resistance in microorganisms
ISBN 1-280-76861-4
9786613679383
0-470-71905-2
0-470-71652-5
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto DRUG RESISTANCE IN MICRO-ORGANISMS; CONTENTS; Chairman's opening remarks; Aspects of the problem of drug resistance in bacteria; Discussion; Indirect selection and origin of resistance; Discussion; Genetic aspects of drug resistance; Discussion; Inheritance in single bacterial cells; Discussion; Penicillin-induced resistance to penicillin in cultures of Bacillus cereus; Discussion; Directed hereditary changes of fermentative properties of yeast by a specific substrate; Discussion; Multiple mechanisms of acquired drug resistance; Discussion
Physiological (phenotypic) mechanisms responsible for drug resistanceDiscussion; Genetic and metabolic mechanisms underlying multiple levels of sulphonamide resistance in pneumococci; Discussion; The phenotypic expression of genes determining various types of drug resistance following their inheritance by sensitive bacteria; Discussion; Specific polyhydroxy compounds as cofactors of enzymic adaptation and its inheritance; Discussion; Development of resistance to streptomycin in Serratia marcescens; Discussion
Distribution of drug-resistant individuals in cultures of Mycobacterium tuberculosisDiscussion; Physiological adaptation of bacteria to antibiotics; Discussion; Drug resistance of staphylococci with special reference to penicillinase production; Discussion; On the identification of genetic and non-genetic variation in bacteria; Discussion; The reactions of the mutagenic alkylating agents with proteins and nucleic acids; Discussion; Genetics of two different mechanisms of resistance to colicins: resistance by loss of specific receptors and im- munity by transfer of colicinogenic factors
DiscussionGeneral Discussion; Chairman's closing remarks
Record Nr. UNINA-9910840998203321
Boston, : Little, Brown, [1957]
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Cold war resistance : the international struggle over antibiotics / / Marc Landas
Cold war resistance : the international struggle over antibiotics / / Marc Landas
Autore Landas Marc <1972->
Pubbl/distr/stampa Lincoln : , : Potomac Books, an imprint of the University of Nebraska Press, , 2020
Descrizione fisica 1 online resource (363 pages) : illustrations
Disciplina 615.7922
Soggetto topico Cold War - Biological warfare
Antibiotics industry - History
Antibiotics - History
Drug resistance in microorganisms
ISBN 1-64012-366-0
1-64012-105-6
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Record Nr. UNINA-9910795624903321
Landas Marc <1972->  
Lincoln : , : Potomac Books, an imprint of the University of Nebraska Press, , 2020
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Cold war resistance : the international struggle over antibiotics / / Marc Landas
Cold war resistance : the international struggle over antibiotics / / Marc Landas
Autore Landas Marc <1972->
Pubbl/distr/stampa Lincoln : , : Potomac Books, an imprint of the University of Nebraska Press, , 2020
Descrizione fisica 1 online resource (363 pages) : illustrations
Disciplina 615.7922
Soggetto topico Cold War - Biological warfare
Antibiotics industry - History
Antibiotics - History
Drug resistance in microorganisms
ISBN 1-64012-366-0
1-64012-105-6
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Record Nr. UNINA-9910825566003321
Landas Marc <1972->  
Lincoln : , : Potomac Books, an imprint of the University of Nebraska Press, , 2020
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Combating antimicrobial resistance : a one health approach to a global threat : proceedings of a workshop / / Ceci Mundaca-Shah, V. Ayano Ogawa, and Anna Nicholson, rapporteurs ; Forum on Microbial Threats, Board on Global Health, Health and Medicine Division, National Academies of Sciences, Engineering, and Medicine
Combating antimicrobial resistance : a one health approach to a global threat : proceedings of a workshop / / Ceci Mundaca-Shah, V. Ayano Ogawa, and Anna Nicholson, rapporteurs ; Forum on Microbial Threats, Board on Global Health, Health and Medicine Division, National Academies of Sciences, Engineering, and Medicine
Pubbl/distr/stampa Washington, District of Columbia : , : National Academies Press, , 2017
Descrizione fisica 1 online resource (152 pages) : illustrations, maps
Disciplina 616.9041
Soggetto topico Drug resistance in microorganisms
Anti-infective agents
Soggetto genere / forma Electronic books.
ISBN 0-309-46653-9
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Record Nr. UNINA-9910480194603321
Washington, District of Columbia : , : National Academies Press, , 2017
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Combating antimicrobial resistance : a one health approach to a global threat : proceedings of a workshop / / Ceci Mundaca-Shah, V. Ayano Ogawa, and Anna Nicholson, rapporteurs ; Forum on Microbial Threats, Board on Global Health, Health and Medicine Division, National Academies of Sciences, Engineering, and Medicine
Combating antimicrobial resistance : a one health approach to a global threat : proceedings of a workshop / / Ceci Mundaca-Shah, V. Ayano Ogawa, and Anna Nicholson, rapporteurs ; Forum on Microbial Threats, Board on Global Health, Health and Medicine Division, National Academies of Sciences, Engineering, and Medicine
Pubbl/distr/stampa Washington, District of Columbia : , : National Academies Press, , 2017
Descrizione fisica 1 online resource (152 pages) : illustrations, maps
Disciplina 616.9041
Soggetto topico Drug resistance in microorganisms
Anti-infective agents
ISBN 0-309-46655-5
0-309-46653-9
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Record Nr. UNINA-9910796356603321
Washington, District of Columbia : , : National Academies Press, , 2017
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui