Clinical Approaches to Hospital Medicine [[electronic resource] ] : Advances, Updates and Controversies / / edited by Kevin Conrad |
Edizione | [1st ed. 2018.] |
Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2018 |
Descrizione fisica | 1 online resource (XV, 314 p. 32 illus., 18 illus. in color.) |
Disciplina | 610.6 |
Soggetto topico |
Practice of medicine
Internal medicine Pharmacy Practice and Hospital Management Internal Medicine Drug Safety and Pharmacovigilance |
ISBN | 3-319-64774-1 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto | Section I – A Clinical Update in Hospital Medicine -- Chapter 1: Diagnosis and Treatment of Heart Failure for Inpatient Providers -- Chapter 2: Hospital Management of Migraine -- Chapter 3: Candidemia: New directions for Management and Treatment -- Chapter 4: Adjunct Corticosteroid Therapy for Patients with Community Acquired Pneumonia -- Chapter 5: Procalcitonin and New Biomarkers -- Chapter 6: New Developments and Treatment Options for Cellulitis in the Hospital -- Chapter 7: An In Depth Look into the Management and Treatment of Delirium -- Chapter 8: Update in the Treatment of Sepsis and Septic Shock; Transitioning from SIRS to SOFA -- Section II - Extended Topics in Hospital Medicine -- Chapter 9: Palliative Medicine -- Chapter 10: Stroke Units and Their Effect on Patient Outcomes -- Chapter 11: An Update in Perioperative Medicine -- Chapter 12: Obstetrics: The Hospitalist’s Approach to the Pregnant Patient -- Section III – The Opiod Epidemic – Tools for the Hospitalist -- Chapter 13: Solving America’s Opiod Epidemic – Pathophysiology and Ethics -- Chapter 14: Solving America’s Opiod Epiedmic – Treatment and Systems Approach -- Chapter 15:The Opioid Risk Tool: Assessing Opioid Risk: Why Is the Sensitive Question Important? -- Chapter 16:Nonopioid and Adjuvant Analgesics for Acute Pain Management -- Chapter 17:Hospitalist Management of Injectable Drugs of Abuse -- Section IV – Perspectives in Hospital Medicine -- Chapter 18:The State of Hospitalist Medicine: Trends in Compensation, Practice Patterns, Advanced Practice Providers, Malpractice and Career Satisfaction -- Chapter 19:The Background and Development of Hospital Medicine Globally: The Challenges of International Hospital Medicine -- Chapter 20: Philosophical Tools for Applying Medical Knowledge. |
Record Nr. | UNINA-9910300306203321 |
Cham : , : Springer International Publishing : , : Imprint : Springer, , 2018 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
|
Clinical Pharmacokinetic and Pharmacodynamic Drug Interactions Associated with Antimalarials [[electronic resource] /] / by Tony K.L. Kiang, Kyle John Wilby, Mary H.H. Ensom |
Autore | Kiang Tony K.L |
Edizione | [1st ed. 2015.] |
Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Adis, , 2015 |
Descrizione fisica | 1 online resource (149 p.) |
Disciplina |
353998
610 613 614.44 |
Soggetto topico |
Tropical medicine
Health promotion Pharmacy Tropical Medicine Health Promotion and Disease Prevention Drug Safety and Pharmacovigilance |
ISBN | 3-319-10527-2 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto | Introduction -- Pharmacology of Recommended Antimalarial Agents -- Drug Interaction Potential of Antimalarial Drugs Based on Known Metabolic Properties of Antimalarials -- Pharmacokinetic Drug Interactions Affecting Antimalarials -- Effects of Antimalarials on the Pharmacokinetics of Co-Administered Drugs -- Effects of Antimalarials on the Pharmacokinetics of Co-Administered Antimalarials -- Pharmacodynamic Interactions: Clinical Evidence for Combination Therapy, In Vitro Interactions, and In Vivo Interactions -- Limitations, Future Directions, and Conclusions. |
Record Nr. | UNINA-9910300188803321 |
Kiang Tony K.L | ||
Cham : , : Springer International Publishing : , : Imprint : Adis, , 2015 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
|
Cognitive Errors and Diagnostic Mistakes [[electronic resource] ] : A Case-Based Guide to Critical Thinking in Medicine / / by Jonathan Howard |
Autore | Howard Jonathan |
Edizione | [1st ed. 2019.] |
Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2019 |
Descrizione fisica | 1 online resource (589 pages) |
Disciplina | 616.075 |
Soggetto topico |
General practice (Medicine)
Health promotion Pharmacy Neurology Diagnostic Errors - prevention & control Medical Errors - prevention & control Clinical Decision-Making Clinical Competence Attitude of Health Personnel General Practice / Family Medicine Health Promotion and Disease Prevention Drug Safety and Pharmacovigilance Neurology |
Soggetto genere / forma | Case Reports. |
ISBN | 3-319-93224-1 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto | An introduction to cognitive biases and how they led to errors and impact medical diagnoses -- Aggregate bias -- Anchoring -- Availability -- Base-rate neglect -- Commission bias -- Diagnosis momentum -- Feedback sanction -- Framing effect -- Fundamental attribution error -- Gambler’s fallacy -- Gender bias -- Hindsight bias -- Multiple alternatives bias -- Omission bias -- Order effects -- Outcome bias -- Overconfidence bias -- Playing the odds -- Posterior probability error -- Premature closure -- Psych-out error -- Representativeness restraint -- Search satisfying -- Sutton’s slip -- Triage cueing -- Unpacking principle -- Vertical line failure -- Visceral bias -- Yin Yang -- Strategies to improve critical thinking and minimize cognitive biases/diagnostic errors. . |
Record Nr. | UNINA-9910337477403321 |
Howard Jonathan | ||
Cham : , : Springer International Publishing : , : Imprint : Springer, , 2019 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
|
Communicating about Risks and Safe Use of Medicines [[electronic resource] ] : Real Life and Applied Research / / edited by Priya Bahri |
Edizione | [1st ed. 2020.] |
Pubbl/distr/stampa | Singapore : , : Springer Singapore : , : Imprint : Adis, , 2020 |
Descrizione fisica | 1 online resource (523 pages) |
Disciplina | 615.1 |
Soggetto topico |
Pharmacy
Drug Safety and Pharmacovigilance Medicaments Avaluació del risc per la salut Comunicació en farmàcia |
Soggetto genere / forma | Llibres electrònics |
ISBN | 981-15-3013-0 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto | Foreword (Baruch Fischhoff) -- Preface: Guide for readers (Priya Bahri) -- Authors’ biographical notes -- Overview of contents in chapters -- 1. A multilayered research framework for humanities and epidemiology of medicinal product risk communication (Priya Bahri) -- Part I: Medicines in real life as communication challenges. 2. Hormonal contraceptives - Communication for risk awareness and informed choice, or a public scare? (Barbara Mintzes, Teresa Alves, with a contribution from Priya Bahri) -- 3. COX-2 inhibitors - Communication of accumulating risk evidence and a product withdrawal (Amy Rogers, Kerr Grieve, Thomas M MacDonald, with a contribution from Sérgio Nishioka) -- 4. Isotretinoin - Communication for preventing birth defects and alerting of an uncertain risk of suicide (Ineke (HJMJ) Crijns) -- 5. Pandemic influenza vaccines - Communication of benefits, risks and uncertainties (Glen J Nowak, Emilie Karafillakis, Heidi Larson) -- Part II: Tackling the challenges – Methods for medicinal product risk communication research. 6. Ethical frameworks (Ghislaine van Thiel) -- 7. The cognitive and behavioural sciences (Sara Rubinelli, Nicola Diviani, Maddalena Fiordelli) -- 8. The social sciences (Brian Taylor, Anne Moorhead) -- 9. Rhetoric and science & technology studies (Mathias Møllebæk) -- 10. Media science and practice (Glen J Nowak, Michael A Cacciatore) -- 11. Social media research (Nabarun Dasgupta, Carly Winokur, Carrie E Pierce) -- 12. Design science with a focus on user-centred evaluation of written information (Jörg Fuchs) -- 13. Dissemination & implementation science (Elaine Morrato, Meredith Smith) -- 14. Pharmacoepidemiology (Bert (HGM) Leufkens) -- 15. Legal frameworks (Burkhard Sträter) -- 16. From passive to active - Patients as contributors to medicinal product risk communication research (François Houÿez) -- Afterword: The dimension of communicating medicine risks in low- and middle-income countries (Nilima A Kshirsagar). |
Record Nr. | UNINA-9910407725603321 |
Singapore : , : Springer Singapore : , : Imprint : Adis, , 2020 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
|
Comprehensive Healthcare Simulation: Pharmacy Education, Practice and Research [[electronic resource] /] / edited by Yaser Mohammed Al-Worafi |
Autore | Al-Worafi Yaser Mohammed |
Edizione | [1st ed. 2023.] |
Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2023 |
Descrizione fisica | 1 online resource (278 pages) |
Disciplina | 615.10711 |
Collana | Comprehensive Healthcare Simulation |
Soggetto topico |
Pharmacy
Pharmacology Pharmacovigilance Public health administration Drug Safety and Pharmacovigilance Health Administration |
ISBN | 3-031-33761-1 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto | Part I. Simulation in Pharmacy Education -- Overview of Simulation in Pharmacy Education -- Patient simulation in Pharmacy Education -- Fidelity simulation in Pharmacy Education -- Computer-based Simulation in Pharmacy Education -- Simulation for Introductory Pharmacy Practice Experience (IPPE) -- Simulation for Advanced Pharmacy Practice Experience (APPE) -- Simulation for Pharmacotherapy -- Simulation for Clinical Pharmacokinetics -- Simulation for Medication Safety -- Simulation for Pharmacology -- Simulation for Pharmaceutical Chemistry -- Simulation for Pharmaceutics and Pharmaceutical Industry -- Simulation for Drug Information and Poisons Services -- Simulation for Complementary and Alternative Medicines and Nutraceuticals -- Simulation for personalized medicine -- Simulation for Clinical Toxicology and Forensic Medicine -- In situ and mobile simulation in pharmacy education -- Facilitators of Simulation in Pharmacy Education -- Barriers of Simulation in Pharmacy Education -- Assessment, Evaluation and Feedback of Simulation in Pharmacy Education -- Effectiveness of simulation in pharmacy education -- Quality standards and recommendations of the simulation in pharmacy education -- Simulation training -- Part II. Simulation for Pharmacy Practice -- Overview of Simulation in Pharmacy Practice -- Simulation in Community Pharmacy Practice -- Simulation in Hospital Pharmacy Practice -- Simulation for communication skills assessment -- Simulation in patient care -- Simulation in the distance and online pharmacy practice: telepharmacy and telehealth -- Simulation for medication safety and patient safety practice -- Assessment, Evaluation and Feedback of Simulation in Pharmacy Practice -- Facilitators of Simulation in Pharmacy Practice -- Barriers of Simulation in Pharmacy Practice -- Quality standards and recommendations of Simulation in Pharmacy Practice -- Part III. Simulation for Pharmacy Research -- Overview of Simulation in Pharmacy Research -- Simulation for Drug Development -- Design simulation-based research in pharmacy -- Recruiting and train the simulated patients/persons -- Data analysis -- Ethics in simulation research -- Simulation research reports and publication -- Facilitators of simulation research -- Barriers of simulation research. |
Record Nr. | UNINA-9910736020703321 |
Al-Worafi Yaser Mohammed | ||
Cham : , : Springer International Publishing : , : Imprint : Springer, , 2023 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
|
Cutaneous Drug Hypersensitivity [[electronic resource] ] : Clinical Features, Mechanisms, Diagnosis, and Management / / edited by Andreas J. Bircher, Howard I. Maibach, Knut Brockow, Annick Barbaud |
Edizione | [1st ed. 2022.] |
Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2022 |
Descrizione fisica | 1 online resource (346 pages) |
Disciplina | 615.778 |
Soggetto topico |
Dermatology
Allergy Internal medicine Pharmacovigilance Primary care (Medicine) Family medicine Allergology Internal Medicine Drug Safety and Pharmacovigilance Primary Care Medicine General Practice and Family Medicine |
ISBN | 3-030-82743-7 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto | Part I. General aspects of drug hypersensitivity -- Chapter 1. Terminology, classifications, chronology -- Chapter 2. Epidemiology -- Chapter 3. Clinical manifestations: Cutaneous signs and syndromes -- Chapter 4. Clinical manifestations: Other organs (kidney, gut, heart, brain etc.) -- Chapter 5. Danger signs in drug hypersensitivity and severity SCORES -- Chapter 6. Pathomechanisms in Drug Hypersensitivities -- Part II. Diagnostic methods -- Chapter 7. Skin tests -- Chapter 8. Serological tests -- Chapter 9. T cell tests -- Chapter 10. Basophil activation tests -- Chapter 11. Histopathology of drug induced exanthemas -- Part III. Management -- Chapter 12. Drug desensitization in immediate-type hypersensitivity -- Chapter 13. Documentation allergy card/pass -- Part IV. Drug hypersensitivity in specific populations -- Chapter 14. Children and Adolescents -- Chapter 15. HIV-Infection and AIDS -- Chapter 16. Oncology. immune checkpoint Inhibitors -- Chapter 17. MC releasing syndromes in drug hypersensitivity -- Part V. Eliciting Drugs -- Chapter 18. Penicillins -- Chapter 19. Cephalosporin Allergy -- Chapter 20. Other Antibiotics -- Chapter 21. Other Antiinfectious drugs -- Chapter 22. Analgesics and non-steroidal antiphlogistic drugs -- Chapter 23. Periinterventional hypersensitivity: Anesthetic drugs and materials -- Chapter 24. Muscle relaxants -- Chapter 25. Anticoagulants -- Chapter 26. Biological drugs -- Chapter 27. Hormones (delayed) -- Chapter 28. Vaccines -- Chapter 29. Antiepileptic and psychotropic drugs -- Chapter 30. PROTON PUMP INHIBITORS -- Chapter 31. Diagnostic agents -- Chapter 32. Hypersensitivity to blood pressure agents -- Chapter 33. Iron preparations -- Chapter 34. Vitamins and supplements -- Chapter 35. Anti-tumor drugs / Cytostatics -- Chapter 36. Photosensitizing drugs -- Chapter 37. Topically applied drugs -- Chapter 38. Additives: Preservatives, Antioxidants (sulfites), Colors, dyes and other. |
Record Nr. | UNINA-9910768200103321 |
Cham : , : Springer International Publishing : , : Imprint : Springer, , 2022 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
|
Drug Discovery and Evaluation: Pharmacological Assays [[electronic resource] /] / edited by Franz J. Hock |
Edizione | [4th ed. 2016.] |
Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2016 |
Descrizione fisica | 1 online resource (32 illus., 20 illus. in color. eReference.) |
Disciplina | 610 |
Collana | Springer Reference |
Soggetto topico |
Medicine
Pharmacology Pharmacy Biomedicine, general Pharmacology/Toxicology Drug Safety and Pharmacovigilance |
ISBN | 3-319-05392-2 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto |
Intro -- Preface to the Fourth Edition -- Contents -- About the Editor -- Contributors -- Part I: Cardiovascular Activity -- Studies in Isolated Organs -- α-Sympatholytic Activity in Isolated Vascular Smooth Muscle -- Purpose and Rationale -- Procedure -- Experimental Course -- Evaluation -- Modifications of the Method -- α-Sympatholytic Activity in the Isolated Guinea Pig Seminal Vesicle -- Purpose and Rationale -- Procedure -- Evaluation -- Modification of the Method -- α-Sympatholytic Activity in the Isolated Vas Deferens of the Rat -- Purpose and Rationale -- Procedure -- Evaluation -- Modifications of the Method -- α-Sympatholytic Activity in the Isolated Rat Spleen -- Purpose and Rationale -- Procedure -- Evaluation -- Modifications of the Method -- α-Sympatholytic Activity in the Isolated Rat Anococcygeus Muscle -- Purpose and Rationale -- Procedure -- Evaluation -- Modifications of the Method -- beta1-Sympatholytic Activity in Isolated Guinea Pig Atria -- Purpose and Rationale -- Procedure -- Right Atrium -- Left Atrium -- Evaluation -- Modifications of the Method -- beta2-Sympatholytic Activity in the Isolated Tracheal Chain -- Purpose and Rationale -- Procedure -- Experimental Course -- Evaluation -- Modifications of the Method -- Angiotensin-Converting Enzyme Inhibition in the Isolated Guinea Pig Ileum -- Purpose and Rationale -- Procedure -- Angiotensin I Antagonism -- Bradykinin Potentiation -- Evaluation -- Angiotensin I Antagonism -- Bradykinin Potentiation -- Modification of the Method -- Contractile and Relaxing Activity on Isolated Blood Vessels Including Effects of Potassium-Channel Openers -- Purpose and Rationale -- Procedure -- Evaluation -- Modifications of the Method -- Isolated Guinea Pig Ureter -- Purpose and Rationale -- Procedure -- Evaluation -- Critical Assessment of the Method -- Modifications of the Method.
Isolated Corpus Cavernosum -- Purpose and Rationale -- Procedure -- Evaluation -- Modifications of the Method -- References and Further Reading -- α-Sympatholytic Activity in Isolated Vascular Smooth Muscle -- α-Sympatholytic Activity in the Isolated Guinea Pig Seminal Vesicle -- α-Sympatholytic Activity in the Isolated Vas Deferens of the Rat -- α-Sympatholytic Activity in the Isolated Rat Spleen -- α-Sympatholytic Activity in the Isolated Rat Anococcygeus Muscle -- beta1-Sympatholytic Activity in Isolated Guinea Pig Atria -- beta2-Sympatholytic Activity in the Isolated Tracheal Chain -- Angiotensin Converting Enzyme Inhibition in the Isolated Guinea Pig Ileum -- Contractile and Relaxing Activity on Isolated Blood Vessels Including Effects of Potassium-Channel Openers -- Isolated Guinea Pig Ureter -- Isolated Corpus Cavernosum -- Cardiovascular Analysis In Vivo -- Hemodynamic Screening in Anesthetized Rats -- Purpose and Rationale -- Procedure -- Evaluation -- Critical Assessment of the Method -- Modifications of the Method -- Blood Pressure in Pithed Rats -- Purpose and Rationale -- Procedure -- Evaluation -- Modifications of the Method -- Antihypertensive Vasodilator Activity in Ganglion-Blocked, Angiotensin II-Supported Rats -- Purpose and Rationale -- Procedure -- Evaluation -- Critical Assessment of the Method -- Modifications of the Method -- Blood Pressure in Conscious Hypertensive Rats (Tail-Cuff Method) -- Purpose and Rationale -- Procedure -- Surgical Procedure to Induce Renal Hypertension -- Test Procedure -- Evaluation -- Critical Assessment of the Method -- Modifications of the Method -- Direct Measurement of Blood Pressure in Conscious Rats with Indwelling Catheter -- Purpose and Rationale -- Procedure -- Preparation of Cannulae -- Implantation of Cannulae -- Measurement of Blood Pressure -- Evaluation. Critical Assessment of the Method -- Modifications of the Method -- Cannulation Techniques in Rodents -- Purpose and Rationale -- Permanent Cannulation of the Jugular Vein in Rats -- Purpose and Rationale -- Procedure -- Modifications of the Method -- Permanent Cannulation of the Renal Vein in Rats -- Purpose and Rationale -- Procedure -- Permanent Cannulation of the Portal Vein in Rats -- Purpose and Rationale -- Procedure -- Permanent Cannulation of the Thoracic Duct in Rats -- Purpose and Rationale -- Procedure -- Portacaval Anastomosis in Rats -- Purpose and Rationale -- Procedure -- Cardiovascular Analysis in Anesthetized Mice -- Purpose and Rationale -- Procedure -- Evaluation -- Modifications of the Method -- Blood Pressure in Anesthetized Cats -- Purpose and Rationale -- Procedure -- Evaluation -- Critical Assessment of the Method -- Modifications of the Method -- Cardiovascular Drug Challenging Experiments in Anesthetized Dogs -- Purpose and Rationale -- Procedure -- Evaluation -- Hemodynamic Analysis in Anesthetized Dogs -- Purpose and Rationale -- Procedure -- Preparation for Hemodynamic Measurements -- Experimental Course -- Calculation of Results and Evaluation -- Modifications of the Method -- Hemodynamic Measurements in Conscious Dogs -- Purpose and Rationale -- Procedure -- Experimental Protocol -- Evaluation -- Modifications of the Method -- Hemodynamic Studies in Monkeys -- Purpose and Rationale -- Procedure -- Evaluation -- Modifications of the Method -- Measurement of Cardiac Output and Regional Blood Flow with Microspheres -- Purpose and Rationale -- Procedure -- Evaluation -- Critical Assessment of the Method -- Modifications of the Method -- Carotid Artery Loop Technique -- Purpose and Rationale -- Procedure -- Critical Assessment of the Method -- Modifications of the Method. Measurement of Heart Dimensions in Anesthetized Dogs -- Purpose and Rationale -- Procedure -- Implantation of Ultrasonic Transducers -- Preparation for Hemodynamic Measurements -- Experimental Course -- Evaluation -- Modifications of the Method -- Telemetric Monitoring of Cardiovascular Parameters in Rats -- Purpose and Rationale -- Procedure -- Evaluation -- Modifications of the Method -- Cardiovascular Effects After Intracerebroventricular Administration -- Purpose and Rationale -- Procedure -- Evaluation -- Modifications of the Method -- Influence on Orthostatic Hypotension -- Purpose and Rationale -- Procedure -- Evaluation -- Modifications of the Method -- Bezold-Jarisch Reflex -- Purpose and Rationale -- Procedure -- Evaluation -- Modifications of the Method -- Endotoxin-Induced Shock -- Purpose and Rationale -- Procedure -- Evaluation -- Modifications of the Method -- Hemorrhagic Shock -- Purpose and Rationale -- Procedure -- Evaluation -- Critical Assessment of the Method -- Modifications of the Method -- Tourniquet Shock -- Purpose and Rationale -- Procedure -- Evaluation -- Critical Evaluation of the Method -- Modifications of the Method -- Heatstroke -- Purpose and Rationale -- Procedure -- Evaluation -- Modifications of the Method -- α- and beta-Adrenoreceptors in the Mouse Iris -- Purpose and Rationale -- Procedure -- Evaluation -- Modifications of the Method -- α2-Adrenoreceptor Blockade Measured In Vivo by Clonidine-Induced Sleep in Chicks -- Purpose and Rationale -- Procedure -- Evaluation -- Critical Assessment of the Method -- Activity at beta1- and beta2-Adrenoreceptors in the Rat -- Purpose and Rationale -- Procedure -- Evaluation of Agonists -- Evaluation of Antagonists -- Critical Assessment of the Method -- Modifications of the Method -- beta1- and beta2-Sympatholytic Activity in Dogs -- Purpose and Rationale -- Procedure. Preparation for Hemodynamic Measurements -- Screening for beta-Blocking Effects in Anesthetized Dogs -- Testing for beta1- and beta2-Blocking Effects: Determination of ED50 -- Evaluation -- Intrinsic beta-Sympathomimetic Activity in Reserpine-Pretreated Dogs -- Purpose and Rationale -- Procedure -- Preparation for Hemodynamic Measurements -- Experimental Course -- Evaluation -- Cat Nictitating Membrane Preparation (Ganglion-Blocking Activity) -- Purpose and Rationale -- Procedure -- Evaluation -- Critical Assessment of the Method -- Modifications of the Method -- Assessment of Ganglion-Blocking Activity in the Isolated Bovine Retractor Penis Muscle -- Purpose and Rationale -- Procedure -- Evaluation -- Critical Assessment of the Method -- Modifications of the Method -- Angiotensin II Antagonism -- Purpose and Rationale -- Procedure -- Intrinsic Agonistic Activity -- Antagonistic Activity -- Duration of Activity -- Evaluation -- Intrinsic Agonistic Activity -- Antagonistic Activity -- Critical Assessment of the Method -- Modifications of the Method -- ACE Inhibition Measured In Vivo in the Rat -- Purpose and Rationale -- Procedure -- Inhibition of Angiotensin I Cleavage -- Potentiation of Bradykinin-Induced Vasodepression -- Evaluation -- Inhibition of Angiotensin I Cleavage -- Potentiation of Bradykinin-Induced Vasodepression -- Critical Assessment of the Method -- Modifications of the Method -- Evaluation of Renin Inhibitors in Dogs -- Purpose and Rationale -- Procedure -- Animal Experiment -- Analytical Procedures -- Evaluation -- Critical Assessment of the Method -- Modifications of the Method -- Evaluation of Renin Inhibitors in Monkeys -- Purpose and Rationale -- Procedure -- Evaluation -- Modifications of the Method -- Critical Assessment of the Method -- Penile Erection in Rabbits -- Purpose and Rationale -- Procedure -- Evaluation. Modifications of the Method. |
Record Nr. | UNINA-9910253870903321 |
Cham : , : Springer International Publishing : , : Imprint : Springer, , 2016 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
|
Drug Therapy and Interactions in Pediatric Oncology [[electronic resource] ] : A Pocket Guide / / by Carolina Witchmichen Penteado Schmidt, Fabiana Gatti de Menezes |
Autore | Penteado Schmidt Carolina Witchmichen |
Edizione | [1st ed. 2017.] |
Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2017 |
Descrizione fisica | 1 online resource (XXI, 212 p. 15 illus. in color.) |
Disciplina | 618.92 |
Soggetto topico |
Pediatrics
Oncology Hematology Pharmacy Cancer research Oncology Drug Safety and Pharmacovigilance Cancer Research |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto | 1. Introduction -- 2. The main diseases in pediatric oncohematology -- 3. The main protocols in pediatric oncohematology -- 4. Background on drug interactions -- 5. Food - drug interactions -- 6. Body surface -- 7. Carboplatin dosage calculation -- 8. Creatinine clearance estimate. |
Record Nr. | UNINA-9910135952103321 |
Penteado Schmidt Carolina Witchmichen | ||
Cham : , : Springer International Publishing : , : Imprint : Springer, , 2017 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
|
Drug Transporters in Drug Disposition, Effects and Toxicity [[electronic resource] /] / edited by Xiaodong Liu, Guoyu Pan |
Edizione | [1st ed. 2019.] |
Pubbl/distr/stampa | Singapore : , : Springer Singapore : , : Imprint : Springer, , 2019 |
Descrizione fisica | 1 online resource (588 pages) |
Disciplina | 615.1 |
Collana | Advances in Experimental Medicine and Biology |
Soggetto topico |
Pharmacology
Pharmacy Medicinal chemistry Pharmacology/Toxicology Drug Safety and Pharmacovigilance Medicinal Chemistry |
ISBN | 981-13-7647-6 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto | Overview: role of drug transporters in drug disposition and its clinical significance -- ABC family transporters -- SLC family transporters -- Current research method in transporter study -- Transporter-mediated drug–drug interactions and their significance -- Roles of hepatic drug transporters in drug disposition and liver toxicity -- Roles of renal drug transporter in drug disposition and renal toxicity -- Intestinal transporter associated toxicity and absorption -- Contributions of drug transporters to blood-brain barriers -- Contributions of drug transporters to blood-retinal barrier(BRB) -- Contributions of drug transporters to blood-placental barrier -- ABC transporter-mediated multidrug-resistant cancer. |
Record Nr. | UNINA-9910350349703321 |
Singapore : , : Springer Singapore : , : Imprint : Springer, , 2019 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
|
Ethical Innovation for Global Health [[electronic resource] ] : Pandemic, Democracy and Ethics in Research / / edited by Chieko Kurihara, Dirceu Greco, Ames Dhai |
Autore | Kurihara Chieko |
Edizione | [1st ed. 2023.] |
Pubbl/distr/stampa | Singapore : , : Springer Nature Singapore : , : Imprint : Springer, , 2023 |
Descrizione fisica | 1 online resource (331 pages) |
Disciplina | 174.2 |
Altri autori (Persone) |
GrecoDirceu
DhaiAmes |
Soggetto topico |
Medical Ethics
Bioethics Pharmacovigilance Medical policy Pharmaceutical chemistry Drug Safety and Pharmacovigilance Health Policy Pharmaceutics |
ISBN | 981-9961-63-7 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto | 1 Introduction to Ethical innovation for global health: pandemic, democracy and ethics in research. Part 1 Relevant constructions from a middle-income country (MIC) and/or non-Western paradigms: Brazil, South Africa, Taiwan, South Korea, and Japan -- 2 Democracy restoration in Brazil, the constitutional guarantee of health as a right for all, giving rise to a universal health system (SUS) and of a National Research Ethics Commission -- 3 Equitable access to COVID-19 vaccines, vaccine research and Vaccine Apartheid on the African continent: challenges and recommendations -- 4 Response to Covid-19 pandemic and Ethical Innovations in Taiwan -- 5 Between truth and profit: Scientific misconduct case of human cloned embryonic stem cell and revisiting cases during COVID-19 pandemic -- 6 Therapeutic misconception as the basis for vaccine nationalism of Japan: a historical reflection and perspectives for global public health -- Part 2 Historical and international perspectives on the development of ethical principles in research involving humans -- 7 The Declaration of Helsinki as a living document: Revisiting its principles in a global pandemic -- 8 Hidden Medical War Crimes and the Emergence of Bioethics in Japan -- 9 From Nuremberg to Helsinki: Historicizing the Codification of Post-War Research Ethics -- 10 CIOMS research guidelines: Considering the needs of developing countries -- 11 Ethics of placebo-controlled trial: historical analysis including the experience of COVID-19 pandemic -- 12 Post-trial access: historical analysis considering the experience of COVID-19 pandemic -- 13 Our “WMA Declaration of Helsinki”: opinions and pro-posals from patient and public for research ethics -- Part 3 Alternative frameworks for innovation and drug development strategies -- 14 Medicines development for global health: Learning from COVID-19 vaccines R&D -- 15 Development of portfolios and pipelines of drugs for the treatment, prevention and control of neglected tropical diseases -- 16 Patient and Public Involvement (PPI) and pharmaceutical development through Open Innovation Processes ~ recent activities. |
Record Nr. | UNINA-9910765490203321 |
Kurihara Chieko | ||
Singapore : , : Springer Nature Singapore : , : Imprint : Springer, , 2023 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
|