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Biblioteca

MARC Lista (tabellare)
Pharmacy and pharmacology communications
Pharmacy and pharmacology communications
Pubbl/distr/stampa London, : Royal Pharmaceutical Society of Great Britain, 1998-©2000
Descrizione fisica 1 online resource
Disciplina 615.105
Soggetto topico Pharmacy
Pharmacology
Communication in pharmacy
Drugs
Clinical pharmacology
Drug Evaluation
Pharmaceutical Preparations
Pharmacology, Clinical
Pharmacie
Pharmacologie
Communication en pharmacie
Médicaments
Pharmacologie clinique
Farmacochemie
Soggetto genere / forma Periodical
Periodicals.
ISSN 2047-9948
Formato Materiale a stampa
Livello bibliografico Periodico
Lingua di pubblicazione eng
Record Nr. UNISA-996214095703316
London, : Royal Pharmaceutical Society of Great Britain, 1998-©2000
Materiale a stampa
Lo trovi qui: Univ. di Salerno
Opac: Controlla la disponibilità qui
Pharmacy and pharmacology communications
Pharmacy and pharmacology communications
Pubbl/distr/stampa London, : Royal Pharmaceutical Society of Great Britain, 1998-©2000
Descrizione fisica 1 online resource
Disciplina 615.105
Soggetto topico Pharmacy
Pharmacology
Communication in pharmacy
Drugs
Clinical pharmacology
Drug Evaluation
Pharmaceutical Preparations
Pharmacology, Clinical
Pharmacie
Pharmacologie
Communication en pharmacie
Médicaments
Pharmacologie clinique
Farmacochemie
Soggetto genere / forma Periodical
Periodicals.
ISSN 2047-9948
Formato Materiale a stampa
Livello bibliografico Periodico
Lingua di pubblicazione eng
Record Nr. UNINA-9910555058903321
London, : Royal Pharmaceutical Society of Great Britain, 1998-©2000
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Post-approval safety data management [[electronic resource] ] : definitions and standards for expedited reporting
Post-approval safety data management [[electronic resource] ] : definitions and standards for expedited reporting
Pubbl/distr/stampa [Rockville, Md.?] : , : [U.S. Dept. of Health and Human Services, Food and Drug Administration], , [2003]
Descrizione fisica 12 : digital, PDF file
Soggetto topico Drugs - Side effects - Reporting
Clinical pharmacology
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Altri titoli varianti Post-approval safety data management
Record Nr. UNINA-9910698975003321
[Rockville, Md.?] : , : [U.S. Dept. of Health and Human Services, Food and Drug Administration], , [2003]
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Principles of clinical pharmacology [[electronic resource] /] / [edited by] Arthur J. Atkinson, Jr. ... [et al.]
Principles of clinical pharmacology [[electronic resource] /] / [edited by] Arthur J. Atkinson, Jr. ... [et al.]
Edizione [3rd ed.]
Pubbl/distr/stampa London, : Elsevier Academic Press, c2012
Descrizione fisica 1 online resource (649 p.)
Disciplina 615.1
615.58
Altri autori (Persone) AtkinsonArthur J
Soggetto topico Clinical pharmacology
Pharmacology
Soggetto genere / forma Electronic books.
ISBN 0-12-385472-5
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Front Cover; Principles of Clinical Pharmacology; Copyright; Contents; Preface to the First Edition; Contributors; Chapter1 - Introduction to Clinical Pharmacology; BACKGROUND; PHARMACOKINETICS; REFERENCES; PARTI - PHARMACOKINETICS; Chapter2 - Clinical Pharmacokinetics; THE TARGET CONCENTRATION STRATEGY; CONCEPTS UNDERLYING CLINICAL PHARMACOKINETICS; MATHEMATICAL BASIS OF CLINICAL PHARMACOKINETICS; REFERENCES; STUDY PROBLEMS; Chapter3 - Compartmental Analysis of Drug Distribution; FIT-FOR-PURPOSE MODELING OF DRUG DISTRIBUTION; PHYSIOLOGICAL SIGNIFICANCE OF DRUG DISTRIBUTION VOLUMES
PHYSIOLOGICAL BASIS OF MULTICOMPARTMENTAL MODELS OF DRUG DISTRIBUTIONCLINICAL CONSEQUENCES OF DIFFERENT DRUG DISTRIBUTION PATTERNS; ESTIMATING MODEL PARAMETERS FROM EXPERIMENTAL DATA; REFERENCES; STUDY PROBLEMS; COMPUTER-BASED TUTORIALS; Chapter4 - Drug Absorption and Bioavailability; DRUG ABSORPTION; BIOAVAILABILITY; KINETICS OF DRUG ABSORPTION AFTER ORAL ADMINISTRATION; REFERENCES; STUDY PROBLEMS; COMPUTER-BASED TUTORIALS; Chapter5 - Effect of Renal Disease on Pharmacokinetics; DRUG DOSING IN PATIENTS WITH IMPAIRED RENAL FUNCTION; EFFECTS OF RENAL DISEASE ON RENAL DRUG EXCRETION MECHANISMS
EFFECTS OF IMPAIRED RENAL FUNCTION ON NON-RENAL METABOLISMEFFECTS OF RENAL DISEASE ON DRUG DISTRIBUTION; EFFECTS OF RENAL DISEASE ON DRUG ABSORPTION; REFERENCES; STUDY PROBLEM; Chapter6 - Pharmacokinetics in Patients Requiring Renal Replacement Therapy; KINETICS OF INTERMITTENT HEMODIALYSIS; KINETICS OF CONTINUOUS AND SUSTAINED RENAL REPLACEMENT THERAPY; CLINICAL CONSIDERATIONS; REFERENCES; COMPUTER-BASED TUTORIAL; Chapter7 - Effect of Liver Disease on Pharmacokinetics; HEPATIC ELIMINATION OF DRUGS; EFFECTS OF LIVER DISEASE ON PHARMACOKINETICS
USE OF THERAPEUTIC DRUGS IN PATIENTS WITH LIVER DISEASEREFERENCES; Chapter8 - Non-Compartmental and Compartmental Approaches to Pharmacokinetic Data Analysis; INTRODUCTION; KINETICS, PHARMACOKINETICS AND PHARMACOKINETIC PARAMETERS; NON-COMPARTMENTAL ANALYSIS; COMPARTMENTAL ANALYSIS; NON-COMPARTMENTAL VS COMPARTMENTAL MODELS; CONCLUSION; REFERENCES; Chapter9 - Distributed Models of Drug Kinetics; INTRODUCTION; CENTRAL ISSUES; DRUG MODALITY I: DELIVERY ACROSS A PLANAR-TISSUE INTERFACE; DRUG MODALITY II: DELIVERY FROM A POINT SOURCE, DIRECT INTERSTITIAL INFUSION; SUMMARY; REFERENCES
Chapter10 - Population PharmacokineticsINTRODUCTION; ANALYSIS OF PHARMACOKINETIC DATA; POPULATION PHARMACOKINETICS; MODEL APPLICATIONS; CONCLUSIONS; REFERENCES; PARTII - DRUG METABOLISM AND TRANSPORT; Chapter11 - Pathways of Drug Metabolism; INTRODUCTION; PHASE I BIOTRANSFORMATIONS; PHASE II BIOTRANSFORMATIONS (CONJUGATIONS); ADDITIONAL EFFECTS ON DRUG METABOLISM; REFERENCES; Chapter12 - Methods of Analysis of Drugs and Drug Metabolites; INTRODUCTION; CHOICE OF ANALYTICAL METHODOLOGY; PRINCIPLES OF ANALYSIS; EXAMPLES OF CURRENT ASSAY METHODS; ASSAY SELECTION; REFERENCES
Chapter13 - Clinical Pharmacogenetics
Record Nr. UNINA-9910465227903321
London, : Elsevier Academic Press, c2012
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Principles of clinical pharmacology [[electronic resource] /] / [edited by] Arthur J. Atkinson, Jr. ... [et al.]
Principles of clinical pharmacology [[electronic resource] /] / [edited by] Arthur J. Atkinson, Jr. ... [et al.]
Edizione [3rd ed.]
Pubbl/distr/stampa London, : Elsevier Academic Press, c2012
Descrizione fisica 1 online resource (649 p.)
Disciplina 615.1
615.58
Altri autori (Persone) AtkinsonArthur J
Soggetto topico Clinical pharmacology
Pharmacology
ISBN 0-12-385472-5
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Front Cover; Principles of Clinical Pharmacology; Copyright; Contents; Preface to the First Edition; Contributors; Chapter1 - Introduction to Clinical Pharmacology; BACKGROUND; PHARMACOKINETICS; REFERENCES; PARTI - PHARMACOKINETICS; Chapter2 - Clinical Pharmacokinetics; THE TARGET CONCENTRATION STRATEGY; CONCEPTS UNDERLYING CLINICAL PHARMACOKINETICS; MATHEMATICAL BASIS OF CLINICAL PHARMACOKINETICS; REFERENCES; STUDY PROBLEMS; Chapter3 - Compartmental Analysis of Drug Distribution; FIT-FOR-PURPOSE MODELING OF DRUG DISTRIBUTION; PHYSIOLOGICAL SIGNIFICANCE OF DRUG DISTRIBUTION VOLUMES
PHYSIOLOGICAL BASIS OF MULTICOMPARTMENTAL MODELS OF DRUG DISTRIBUTIONCLINICAL CONSEQUENCES OF DIFFERENT DRUG DISTRIBUTION PATTERNS; ESTIMATING MODEL PARAMETERS FROM EXPERIMENTAL DATA; REFERENCES; STUDY PROBLEMS; COMPUTER-BASED TUTORIALS; Chapter4 - Drug Absorption and Bioavailability; DRUG ABSORPTION; BIOAVAILABILITY; KINETICS OF DRUG ABSORPTION AFTER ORAL ADMINISTRATION; REFERENCES; STUDY PROBLEMS; COMPUTER-BASED TUTORIALS; Chapter5 - Effect of Renal Disease on Pharmacokinetics; DRUG DOSING IN PATIENTS WITH IMPAIRED RENAL FUNCTION; EFFECTS OF RENAL DISEASE ON RENAL DRUG EXCRETION MECHANISMS
EFFECTS OF IMPAIRED RENAL FUNCTION ON NON-RENAL METABOLISMEFFECTS OF RENAL DISEASE ON DRUG DISTRIBUTION; EFFECTS OF RENAL DISEASE ON DRUG ABSORPTION; REFERENCES; STUDY PROBLEM; Chapter6 - Pharmacokinetics in Patients Requiring Renal Replacement Therapy; KINETICS OF INTERMITTENT HEMODIALYSIS; KINETICS OF CONTINUOUS AND SUSTAINED RENAL REPLACEMENT THERAPY; CLINICAL CONSIDERATIONS; REFERENCES; COMPUTER-BASED TUTORIAL; Chapter7 - Effect of Liver Disease on Pharmacokinetics; HEPATIC ELIMINATION OF DRUGS; EFFECTS OF LIVER DISEASE ON PHARMACOKINETICS
USE OF THERAPEUTIC DRUGS IN PATIENTS WITH LIVER DISEASEREFERENCES; Chapter8 - Non-Compartmental and Compartmental Approaches to Pharmacokinetic Data Analysis; INTRODUCTION; KINETICS, PHARMACOKINETICS AND PHARMACOKINETIC PARAMETERS; NON-COMPARTMENTAL ANALYSIS; COMPARTMENTAL ANALYSIS; NON-COMPARTMENTAL VS COMPARTMENTAL MODELS; CONCLUSION; REFERENCES; Chapter9 - Distributed Models of Drug Kinetics; INTRODUCTION; CENTRAL ISSUES; DRUG MODALITY I: DELIVERY ACROSS A PLANAR-TISSUE INTERFACE; DRUG MODALITY II: DELIVERY FROM A POINT SOURCE, DIRECT INTERSTITIAL INFUSION; SUMMARY; REFERENCES
Chapter10 - Population PharmacokineticsINTRODUCTION; ANALYSIS OF PHARMACOKINETIC DATA; POPULATION PHARMACOKINETICS; MODEL APPLICATIONS; CONCLUSIONS; REFERENCES; PARTII - DRUG METABOLISM AND TRANSPORT; Chapter11 - Pathways of Drug Metabolism; INTRODUCTION; PHASE I BIOTRANSFORMATIONS; PHASE II BIOTRANSFORMATIONS (CONJUGATIONS); ADDITIONAL EFFECTS ON DRUG METABOLISM; REFERENCES; Chapter12 - Methods of Analysis of Drugs and Drug Metabolites; INTRODUCTION; CHOICE OF ANALYTICAL METHODOLOGY; PRINCIPLES OF ANALYSIS; EXAMPLES OF CURRENT ASSAY METHODS; ASSAY SELECTION; REFERENCES
Chapter13 - Clinical Pharmacogenetics
Record Nr. UNINA-9910791924903321
London, : Elsevier Academic Press, c2012
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Principles of clinical pharmacology [[electronic resource] /] / [edited by] Arthur J. Atkinson, Jr. ... [et al.]
Principles of clinical pharmacology [[electronic resource] /] / [edited by] Arthur J. Atkinson, Jr. ... [et al.]
Edizione [3rd ed.]
Pubbl/distr/stampa London, : Elsevier Academic Press, c2012
Descrizione fisica 1 online resource (649 p.)
Disciplina 615.1
615.58
Altri autori (Persone) AtkinsonArthur J
Soggetto topico Clinical pharmacology
Pharmacology
ISBN 0-12-385472-5
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Front Cover; Principles of Clinical Pharmacology; Copyright; Contents; Preface to the First Edition; Contributors; Chapter1 - Introduction to Clinical Pharmacology; BACKGROUND; PHARMACOKINETICS; REFERENCES; PARTI - PHARMACOKINETICS; Chapter2 - Clinical Pharmacokinetics; THE TARGET CONCENTRATION STRATEGY; CONCEPTS UNDERLYING CLINICAL PHARMACOKINETICS; MATHEMATICAL BASIS OF CLINICAL PHARMACOKINETICS; REFERENCES; STUDY PROBLEMS; Chapter3 - Compartmental Analysis of Drug Distribution; FIT-FOR-PURPOSE MODELING OF DRUG DISTRIBUTION; PHYSIOLOGICAL SIGNIFICANCE OF DRUG DISTRIBUTION VOLUMES
PHYSIOLOGICAL BASIS OF MULTICOMPARTMENTAL MODELS OF DRUG DISTRIBUTIONCLINICAL CONSEQUENCES OF DIFFERENT DRUG DISTRIBUTION PATTERNS; ESTIMATING MODEL PARAMETERS FROM EXPERIMENTAL DATA; REFERENCES; STUDY PROBLEMS; COMPUTER-BASED TUTORIALS; Chapter4 - Drug Absorption and Bioavailability; DRUG ABSORPTION; BIOAVAILABILITY; KINETICS OF DRUG ABSORPTION AFTER ORAL ADMINISTRATION; REFERENCES; STUDY PROBLEMS; COMPUTER-BASED TUTORIALS; Chapter5 - Effect of Renal Disease on Pharmacokinetics; DRUG DOSING IN PATIENTS WITH IMPAIRED RENAL FUNCTION; EFFECTS OF RENAL DISEASE ON RENAL DRUG EXCRETION MECHANISMS
EFFECTS OF IMPAIRED RENAL FUNCTION ON NON-RENAL METABOLISMEFFECTS OF RENAL DISEASE ON DRUG DISTRIBUTION; EFFECTS OF RENAL DISEASE ON DRUG ABSORPTION; REFERENCES; STUDY PROBLEM; Chapter6 - Pharmacokinetics in Patients Requiring Renal Replacement Therapy; KINETICS OF INTERMITTENT HEMODIALYSIS; KINETICS OF CONTINUOUS AND SUSTAINED RENAL REPLACEMENT THERAPY; CLINICAL CONSIDERATIONS; REFERENCES; COMPUTER-BASED TUTORIAL; Chapter7 - Effect of Liver Disease on Pharmacokinetics; HEPATIC ELIMINATION OF DRUGS; EFFECTS OF LIVER DISEASE ON PHARMACOKINETICS
USE OF THERAPEUTIC DRUGS IN PATIENTS WITH LIVER DISEASEREFERENCES; Chapter8 - Non-Compartmental and Compartmental Approaches to Pharmacokinetic Data Analysis; INTRODUCTION; KINETICS, PHARMACOKINETICS AND PHARMACOKINETIC PARAMETERS; NON-COMPARTMENTAL ANALYSIS; COMPARTMENTAL ANALYSIS; NON-COMPARTMENTAL VS COMPARTMENTAL MODELS; CONCLUSION; REFERENCES; Chapter9 - Distributed Models of Drug Kinetics; INTRODUCTION; CENTRAL ISSUES; DRUG MODALITY I: DELIVERY ACROSS A PLANAR-TISSUE INTERFACE; DRUG MODALITY II: DELIVERY FROM A POINT SOURCE, DIRECT INTERSTITIAL INFUSION; SUMMARY; REFERENCES
Chapter10 - Population PharmacokineticsINTRODUCTION; ANALYSIS OF PHARMACOKINETIC DATA; POPULATION PHARMACOKINETICS; MODEL APPLICATIONS; CONCLUSIONS; REFERENCES; PARTII - DRUG METABOLISM AND TRANSPORT; Chapter11 - Pathways of Drug Metabolism; INTRODUCTION; PHASE I BIOTRANSFORMATIONS; PHASE II BIOTRANSFORMATIONS (CONJUGATIONS); ADDITIONAL EFFECTS ON DRUG METABOLISM; REFERENCES; Chapter12 - Methods of Analysis of Drugs and Drug Metabolites; INTRODUCTION; CHOICE OF ANALYTICAL METHODOLOGY; PRINCIPLES OF ANALYSIS; EXAMPLES OF CURRENT ASSAY METHODS; ASSAY SELECTION; REFERENCES
Chapter13 - Clinical Pharmacogenetics
Record Nr. UNINA-9910812425903321
London, : Elsevier Academic Press, c2012
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Principles of clinical pharmacology [[electronic resource] /] / Arthur J. Atkinson, Jr. ... [et al.]
Principles of clinical pharmacology [[electronic resource] /] / Arthur J. Atkinson, Jr. ... [et al.]
Edizione [2nd ed.]
Pubbl/distr/stampa Amsterdam ; ; Oxford, : Academic, c2007
Descrizione fisica 1 online resource (567 p.)
Disciplina 615.1
Soggetto topico Clinical pharmacology
Drugs
Soggetto genere / forma Electronic books.
ISBN 1-280-72891-4
9786610728916
0-08-046642-7
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Front cover; Title page; Copyright page; Table of contents; Preface to the First Edition; Preface to the Second Edition; Contributors; CHAPTER 1. Introduction to Clinical Pharmacology; BACKGROUND; PHARMACOKINETICS; PART I: PHARMACOKINETICS; CHAPTER 2. Clinical Pharmacokinetics; THE TARGET CONCENTRATION STRATEGY; CONCEPTS UNDERLYING CLINICAL PHARMACOKINETICS; MATHEMATICAL BASIS OF CLINICAL PHARMACOKINETICS; CHAPTER 3. Compartmental Analysis of Drug Distribution; PHYSIOLOGICAL SIGNIFICANCE OF DRUG DISTRIBUTION VOLUMES; PHYSIOLOGICAL BASIS OF MULTICOMPARTMENTAL MODELS OF DRUG DISTRIBUTION
CLINICAL CONSEQUENCES OF DIFFERENT DRUG DISTRIBUTION PATTERNSANALYSIS OF EXPERIMENTAL DATA; CHAPTER 4. Drug Absorption and Bioavailability; DRUG ABSORPTION; BIOAVAILABILITY; KINETICS OF DRUG ABSORPTION AFTER ORAL ADMINISTRATION; CHAPTER 5. Effects of Renal Disease on Pharmacokinetics; EFFECTS OF RENAL DISEASE ON DRUG ELIMINATION; EFFECTS OF RENAL DISEASE ON DRUG DISTRIBUTION; EFFECTS OF RENAL DISEASE ON DRUG ABSORPTION; CHAPTER 6. Pharmacokinetics in Patients Requiring Renal Replacement Therapy; KINETICS OF INTERMITTENT HEMODIALYSIS; KINETICS OF CONTINUOUS RENAL REPLACEMENT THERAPY
CLINICAL CONSIDERATIONSCHAPTER 7. Effect of Liver Disease on Pharmacokinetics; HEPATIC ELIMINATION OF DRUGS; EFFECTS OF LIVER DISEASE ON PHARMACOKINETICS; USE OF THERAPEUTIC DRUGS IN PATIENTS WITH LIVER DISEASE; CHAPTER 8. Noncompartmental versus Compartmental Approaches to Pharmacokinetic Analysis; INTRODUCTION; KINETICS, PHARMACOKINETICS, AND PHARMACOKINETIC PARAMETERS; NONCOMPARTMENTAL ANALYSIS; COMPARTMENTAL ANALYSIS; NONCOMPARTMENTAL VERSUS COMPARTMENTAL MODELS; CONCLUSION; CHAPTER 9. Distributed Models of Drug Kinetics; INTRODUCTION; CENTRAL ISSUES
DRUG MODALITY I: DELIVERY ACROSS A PLANAR - TISSUE INTERFACEDRUG MODALITY II: DELIVERY FROM A POINT SOURCE - DIRECT INTERSTITIAL INFUSION; SUMMARY; CHAPTER 10. Population Pharmacokinetics; INTRODUCTION; ANALYSIS OF PHARMACOKINETIC DATA; POPULATION PHARMACOKINETICS; MODEL APPLICATIONS; CONCLUSIONS; PART II: DRUG METABOLISM AND TRANSPORT; CHAPTER 11. Pathways of Drug Metabolism; INTRODUCTION; PHASE I BIOTRANSFORMATIONS; PHASE II BIOTRANSFORMATIONS (CONJUGATIONS); ADDITIONAL EFFECTS ON DRUG METABOLISM; CHAPTER 12. Methods of Analysis of Drugs and Drug Metabolites; INTRODUCTION
CHOICE OF ANALYTICAL METHODOLOGYCHROMATOGRAPHIC SEPARATIONS; ABSORPTION AND EMISSION SPECTROSCOPY; IMMUNOAFFINITY ASSAYS; MASS SPECTROMETRY; EXAMPLES OF CURRENT ASSAY METHODS; CHAPTER 13. Clinical Pharmacogenetics; INTRODUCTION; HIERARCHY OF PHARMACOGENETIC INFORMATION; IDENTIFICATION AND SELECTION OF OUTLIERS IN A POPULATION; EXAMPLES OF IMPORTANT GENETIC POLYMORPHISMS; CONCLUSIONS AND FUTURE DIRECTIONS; CHAPTER 14. Equilibrative and Concentrative Transport Mechanisms; INTRODUCTION; MECHANISMS OF TRANSPORT ACROSS BIOLOGICAL MEMBRANES; DESCRIPTION OF SELECTED MEMBRANE PROTEIN TRANSPORTERS
ROLE OF TRANSPORTERS IN PHARMACOKINETICS AND DRUG ACTION
Record Nr. UNINA-9910458649003321
Amsterdam ; ; Oxford, : Academic, c2007
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Principles of clinical pharmacology [[electronic resource] /] / Arthur J. Atkinson, Jr. ... [et al.]
Principles of clinical pharmacology [[electronic resource] /] / Arthur J. Atkinson, Jr. ... [et al.]
Edizione [2nd ed.]
Pubbl/distr/stampa Amsterdam ; ; Oxford, : Academic, c2007
Descrizione fisica 1 online resource (567 p.)
Disciplina 615.1
Soggetto topico Clinical pharmacology
Drugs
ISBN 1-280-72891-4
9786610728916
0-08-046642-7
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Front cover; Title page; Copyright page; Table of contents; Preface to the First Edition; Preface to the Second Edition; Contributors; CHAPTER 1. Introduction to Clinical Pharmacology; BACKGROUND; PHARMACOKINETICS; PART I: PHARMACOKINETICS; CHAPTER 2. Clinical Pharmacokinetics; THE TARGET CONCENTRATION STRATEGY; CONCEPTS UNDERLYING CLINICAL PHARMACOKINETICS; MATHEMATICAL BASIS OF CLINICAL PHARMACOKINETICS; CHAPTER 3. Compartmental Analysis of Drug Distribution; PHYSIOLOGICAL SIGNIFICANCE OF DRUG DISTRIBUTION VOLUMES; PHYSIOLOGICAL BASIS OF MULTICOMPARTMENTAL MODELS OF DRUG DISTRIBUTION
CLINICAL CONSEQUENCES OF DIFFERENT DRUG DISTRIBUTION PATTERNSANALYSIS OF EXPERIMENTAL DATA; CHAPTER 4. Drug Absorption and Bioavailability; DRUG ABSORPTION; BIOAVAILABILITY; KINETICS OF DRUG ABSORPTION AFTER ORAL ADMINISTRATION; CHAPTER 5. Effects of Renal Disease on Pharmacokinetics; EFFECTS OF RENAL DISEASE ON DRUG ELIMINATION; EFFECTS OF RENAL DISEASE ON DRUG DISTRIBUTION; EFFECTS OF RENAL DISEASE ON DRUG ABSORPTION; CHAPTER 6. Pharmacokinetics in Patients Requiring Renal Replacement Therapy; KINETICS OF INTERMITTENT HEMODIALYSIS; KINETICS OF CONTINUOUS RENAL REPLACEMENT THERAPY
CLINICAL CONSIDERATIONSCHAPTER 7. Effect of Liver Disease on Pharmacokinetics; HEPATIC ELIMINATION OF DRUGS; EFFECTS OF LIVER DISEASE ON PHARMACOKINETICS; USE OF THERAPEUTIC DRUGS IN PATIENTS WITH LIVER DISEASE; CHAPTER 8. Noncompartmental versus Compartmental Approaches to Pharmacokinetic Analysis; INTRODUCTION; KINETICS, PHARMACOKINETICS, AND PHARMACOKINETIC PARAMETERS; NONCOMPARTMENTAL ANALYSIS; COMPARTMENTAL ANALYSIS; NONCOMPARTMENTAL VERSUS COMPARTMENTAL MODELS; CONCLUSION; CHAPTER 9. Distributed Models of Drug Kinetics; INTRODUCTION; CENTRAL ISSUES
DRUG MODALITY I: DELIVERY ACROSS A PLANAR - TISSUE INTERFACEDRUG MODALITY II: DELIVERY FROM A POINT SOURCE - DIRECT INTERSTITIAL INFUSION; SUMMARY; CHAPTER 10. Population Pharmacokinetics; INTRODUCTION; ANALYSIS OF PHARMACOKINETIC DATA; POPULATION PHARMACOKINETICS; MODEL APPLICATIONS; CONCLUSIONS; PART II: DRUG METABOLISM AND TRANSPORT; CHAPTER 11. Pathways of Drug Metabolism; INTRODUCTION; PHASE I BIOTRANSFORMATIONS; PHASE II BIOTRANSFORMATIONS (CONJUGATIONS); ADDITIONAL EFFECTS ON DRUG METABOLISM; CHAPTER 12. Methods of Analysis of Drugs and Drug Metabolites; INTRODUCTION
CHOICE OF ANALYTICAL METHODOLOGYCHROMATOGRAPHIC SEPARATIONS; ABSORPTION AND EMISSION SPECTROSCOPY; IMMUNOAFFINITY ASSAYS; MASS SPECTROMETRY; EXAMPLES OF CURRENT ASSAY METHODS; CHAPTER 13. Clinical Pharmacogenetics; INTRODUCTION; HIERARCHY OF PHARMACOGENETIC INFORMATION; IDENTIFICATION AND SELECTION OF OUTLIERS IN A POPULATION; EXAMPLES OF IMPORTANT GENETIC POLYMORPHISMS; CONCLUSIONS AND FUTURE DIRECTIONS; CHAPTER 14. Equilibrative and Concentrative Transport Mechanisms; INTRODUCTION; MECHANISMS OF TRANSPORT ACROSS BIOLOGICAL MEMBRANES; DESCRIPTION OF SELECTED MEMBRANE PROTEIN TRANSPORTERS
ROLE OF TRANSPORTERS IN PHARMACOKINETICS AND DRUG ACTION
Record Nr. UNINA-9910784647603321
Amsterdam ; ; Oxford, : Academic, c2007
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Principles of clinical pharmacology [[electronic resource] /] / Arthur J. Atkinson, Jr. ... [et al.]
Principles of clinical pharmacology [[electronic resource] /] / Arthur J. Atkinson, Jr. ... [et al.]
Edizione [2nd ed.]
Pubbl/distr/stampa Amsterdam ; ; Oxford, : Academic, c2007
Descrizione fisica 1 online resource (567 p.)
Disciplina 615.1
Soggetto topico Clinical pharmacology
Drugs
ISBN 1-280-72891-4
9786610728916
0-08-046642-7
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Front cover; Title page; Copyright page; Table of contents; Preface to the First Edition; Preface to the Second Edition; Contributors; CHAPTER 1. Introduction to Clinical Pharmacology; BACKGROUND; PHARMACOKINETICS; PART I: PHARMACOKINETICS; CHAPTER 2. Clinical Pharmacokinetics; THE TARGET CONCENTRATION STRATEGY; CONCEPTS UNDERLYING CLINICAL PHARMACOKINETICS; MATHEMATICAL BASIS OF CLINICAL PHARMACOKINETICS; CHAPTER 3. Compartmental Analysis of Drug Distribution; PHYSIOLOGICAL SIGNIFICANCE OF DRUG DISTRIBUTION VOLUMES; PHYSIOLOGICAL BASIS OF MULTICOMPARTMENTAL MODELS OF DRUG DISTRIBUTION
CLINICAL CONSEQUENCES OF DIFFERENT DRUG DISTRIBUTION PATTERNSANALYSIS OF EXPERIMENTAL DATA; CHAPTER 4. Drug Absorption and Bioavailability; DRUG ABSORPTION; BIOAVAILABILITY; KINETICS OF DRUG ABSORPTION AFTER ORAL ADMINISTRATION; CHAPTER 5. Effects of Renal Disease on Pharmacokinetics; EFFECTS OF RENAL DISEASE ON DRUG ELIMINATION; EFFECTS OF RENAL DISEASE ON DRUG DISTRIBUTION; EFFECTS OF RENAL DISEASE ON DRUG ABSORPTION; CHAPTER 6. Pharmacokinetics in Patients Requiring Renal Replacement Therapy; KINETICS OF INTERMITTENT HEMODIALYSIS; KINETICS OF CONTINUOUS RENAL REPLACEMENT THERAPY
CLINICAL CONSIDERATIONSCHAPTER 7. Effect of Liver Disease on Pharmacokinetics; HEPATIC ELIMINATION OF DRUGS; EFFECTS OF LIVER DISEASE ON PHARMACOKINETICS; USE OF THERAPEUTIC DRUGS IN PATIENTS WITH LIVER DISEASE; CHAPTER 8. Noncompartmental versus Compartmental Approaches to Pharmacokinetic Analysis; INTRODUCTION; KINETICS, PHARMACOKINETICS, AND PHARMACOKINETIC PARAMETERS; NONCOMPARTMENTAL ANALYSIS; COMPARTMENTAL ANALYSIS; NONCOMPARTMENTAL VERSUS COMPARTMENTAL MODELS; CONCLUSION; CHAPTER 9. Distributed Models of Drug Kinetics; INTRODUCTION; CENTRAL ISSUES
DRUG MODALITY I: DELIVERY ACROSS A PLANAR - TISSUE INTERFACEDRUG MODALITY II: DELIVERY FROM A POINT SOURCE - DIRECT INTERSTITIAL INFUSION; SUMMARY; CHAPTER 10. Population Pharmacokinetics; INTRODUCTION; ANALYSIS OF PHARMACOKINETIC DATA; POPULATION PHARMACOKINETICS; MODEL APPLICATIONS; CONCLUSIONS; PART II: DRUG METABOLISM AND TRANSPORT; CHAPTER 11. Pathways of Drug Metabolism; INTRODUCTION; PHASE I BIOTRANSFORMATIONS; PHASE II BIOTRANSFORMATIONS (CONJUGATIONS); ADDITIONAL EFFECTS ON DRUG METABOLISM; CHAPTER 12. Methods of Analysis of Drugs and Drug Metabolites; INTRODUCTION
CHOICE OF ANALYTICAL METHODOLOGYCHROMATOGRAPHIC SEPARATIONS; ABSORPTION AND EMISSION SPECTROSCOPY; IMMUNOAFFINITY ASSAYS; MASS SPECTROMETRY; EXAMPLES OF CURRENT ASSAY METHODS; CHAPTER 13. Clinical Pharmacogenetics; INTRODUCTION; HIERARCHY OF PHARMACOGENETIC INFORMATION; IDENTIFICATION AND SELECTION OF OUTLIERS IN A POPULATION; EXAMPLES OF IMPORTANT GENETIC POLYMORPHISMS; CONCLUSIONS AND FUTURE DIRECTIONS; CHAPTER 14. Equilibrative and Concentrative Transport Mechanisms; INTRODUCTION; MECHANISMS OF TRANSPORT ACROSS BIOLOGICAL MEMBRANES; DESCRIPTION OF SELECTED MEMBRANE PROTEIN TRANSPORTERS
ROLE OF TRANSPORTERS IN PHARMACOKINETICS AND DRUG ACTION
Record Nr. UNINA-9910813758003321
Amsterdam ; ; Oxford, : Academic, c2007
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Rapid clinical pharmacology [[electronic resource] ] : a student formulary / / Andrew Batchelder ... [et al.]
Rapid clinical pharmacology [[electronic resource] ] : a student formulary / / Andrew Batchelder ... [et al.]
Edizione [1st ed.]
Pubbl/distr/stampa Chichester, U.K., : Wiley-Blackwell, 2011
Descrizione fisica 1 online resource (146 p.)
Disciplina 615/.1
Altri autori (Persone) BatchelderAndrew
Collana Rapid series
Soggetto topico Clinical pharmacology
Soggetto genere / forma Electronic books.
ISBN 1-119-54846-2
1-118-29306-1
1-283-40429-X
9786613404299
1-118-29307-X
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Basic pharmacokinetic concepts -- Gastro-intestinal system -- Cardiovascular system -- Respiratory system -- Central nervous system infections -- Endocrine system -- Obstetrics, gynaecology, and urinary tract disorders -- Malignant disease and immunosuppression -- Musculoskeletal and joint diseases -- Eye -- Anaesthesia -- Intravenous fluids -- Blood and transfusion medicine.
Record Nr. UNINA-9910461569703321
Chichester, U.K., : Wiley-Blackwell, 2011
Materiale a stampa
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