JACC : Basic to translational science |
Pubbl/distr/stampa | [New York] : , : Elsevier on behalf of the American College of Cardiology Foundation, , [2016]- |
Descrizione fisica | 1 online resource |
Disciplina | 610.72 |
Soggetto topico |
Clinical medicine - Research
Medicine, Experimental Translational Research, Biomedical |
Soggetto genere / forma | Periodical |
Formato | Materiale a stampa ![]() |
Livello bibliografico | Periodico |
Lingua di pubblicazione | eng |
Nota di contenuto | Introducing JACC: Basic to Translational Science: Why Now? -- Kinetics and Signal Activation Properties of Circulating Factor(s) From Healthy Volunteers Undergoing Remote Ischemic Pre-Conditioning -- Cardiosphere-Derived Cells Reverse Heart Failure With Preserved Ejection Fraction in Rats by Decreasing Fibrosis and Inflammation -- Extracellular Matrix Hydrogel Promotes Tissue Remodeling, Arteriogenesis, and Perfusion in a Rat Hindlimb Ischemia Model -- Telomerase Inhibition by Everolimus Suppresses Smooth Muscle Cell Proliferation and Neointima Formation Through Epigenetic Gene Silencing -- The Role of the L-Type Ca2+ Channel in Altered Metabolic Activity in a Murine Model of Hypertrophic CardiomyopathyCell Therapy for Heart Failure With Preserved Ejection Fraction -- Better Blood Flow Delivered: Extracellular Matrix-Derived Hydrogels for the Induction of Arteriogenesis in Peripheral Artery Disease? -- Point-of-Care Technologies for Precision Cardiovascular Care and Clinical Research: National Heart, Lung, and Blood Institute Working Group -- Broadview Ventures: Investing in the Future of Cardiovascular Technology. |
Record Nr. | UNINA-9910210142803321 |
[New York] : , : Elsevier on behalf of the American College of Cardiology Foundation, , [2016]- | ||
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Lo trovi qui: Univ. Federico II | ||
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JACC : Basic to translational science |
Pubbl/distr/stampa | [New York] : , : Elsevier on behalf of the American College of Cardiology Foundation, , [2016]- |
Descrizione fisica | 1 online resource |
Disciplina | 610.72 |
Soggetto topico |
Clinical medicine - Research
Medicine, Experimental Translational Research, Biomedical |
Soggetto genere / forma | Periodical |
Formato | Materiale a stampa ![]() |
Livello bibliografico | Periodico |
Lingua di pubblicazione | eng |
Nota di contenuto | Introducing JACC: Basic to Translational Science: Why Now? -- Kinetics and Signal Activation Properties of Circulating Factor(s) From Healthy Volunteers Undergoing Remote Ischemic Pre-Conditioning -- Cardiosphere-Derived Cells Reverse Heart Failure With Preserved Ejection Fraction in Rats by Decreasing Fibrosis and Inflammation -- Extracellular Matrix Hydrogel Promotes Tissue Remodeling, Arteriogenesis, and Perfusion in a Rat Hindlimb Ischemia Model -- Telomerase Inhibition by Everolimus Suppresses Smooth Muscle Cell Proliferation and Neointima Formation Through Epigenetic Gene Silencing -- The Role of the L-Type Ca2+ Channel in Altered Metabolic Activity in a Murine Model of Hypertrophic CardiomyopathyCell Therapy for Heart Failure With Preserved Ejection Fraction -- Better Blood Flow Delivered: Extracellular Matrix-Derived Hydrogels for the Induction of Arteriogenesis in Peripheral Artery Disease? -- Point-of-Care Technologies for Precision Cardiovascular Care and Clinical Research: National Heart, Lung, and Blood Institute Working Group -- Broadview Ventures: Investing in the Future of Cardiovascular Technology. |
Record Nr. | UNISA-996267048603316 |
[New York] : , : Elsevier on behalf of the American College of Cardiology Foundation, , [2016]- | ||
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Lo trovi qui: Univ. di Salerno | ||
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JDR clinical and translational research |
Pubbl/distr/stampa | Thousand Oaks, CA : , : Sage Publications, , [2016]- |
Descrizione fisica | 1 online resource |
Disciplina | 617 |
Soggetto topico |
Clinical medicine - Research
Medicine, Experimental Dental Research Translational Medical Research |
Soggetto genere / forma |
Periodicals.
Periodical |
ISSN | 2380-0852 |
Formato | Materiale a stampa ![]() |
Livello bibliografico | Periodico |
Lingua di pubblicazione | eng |
Altri titoli varianti |
Journal of Dental Research clinical and translational research
JDR CTR JCT |
Record Nr. | UNINA-9910617321403321 |
Thousand Oaks, CA : , : Sage Publications, , [2016]- | ||
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Lo trovi qui: Univ. Federico II | ||
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JDR clinical and translational research |
Pubbl/distr/stampa | Thousand Oaks, CA : , : Sage Publications, , [2016]- |
Descrizione fisica | 1 online resource |
Disciplina | 617 |
Soggetto topico |
Clinical medicine - Research
Medicine, Experimental Dental Research Translational Research, Biomedical |
Soggetto genere / forma |
Periodical
Periodicals. |
ISSN | 2380-0852 |
Formato | Materiale a stampa ![]() |
Livello bibliografico | Periodico |
Lingua di pubblicazione | eng |
Altri titoli varianti |
Journal of Dental Research clinical and translational research
JDR CTR JCT |
Record Nr. | UNISA-996251341303316 |
Thousand Oaks, CA : , : Sage Publications, , [2016]- | ||
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Lo trovi qui: Univ. di Salerno | ||
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Journal of clinical and translational science |
Pubbl/distr/stampa | Cambridge : , : Cambridge University Press, , [2017]- |
Descrizione fisica | 1 online resource |
Disciplina | 616 |
Soggetto topico |
Medicine, Experimental
Human experimentation in medicine Clinical medicine - Research |
Soggetto genere / forma |
Periodical
Fulltext Internet Resources. Periodicals. |
ISSN | 2059-8661 |
Formato | Materiale a stampa ![]() |
Livello bibliografico | Periodico |
Lingua di pubblicazione | eng |
Nota di contenuto | Welcome to your Journal of Clinical and Translational Science -- Certification of clinical and translational researchers: An ill-conceived notion -- Enhancing Clinical Research Professionals' Training and Qualifications (ECRPTQ): Recommendations for Good Clinical Practice (GCP) training for investigators and study coordinators -- Education and training of clinical and translational study investigators and research coordinators: A competency-based approach -- Best practices in social and behavioral research: report from the Enhancing Clinical Research Professional's Training and Qualifications project -- A consult service to support and promote community-based research: Tracking and evaluating a community-based research consult service -- Mapping the evolving definitions of translational research -- Understanding investigators' attitudes through a results-based accountability framework within a single CTSA institution -- From community engagement, to community-engaged research, to broadly engaged team science -- Interdisciplinary dissemination and implementation research to advance translational science: Challenges and opportunities -- The continued evolution of team science -- Patient-Centered Network of Learning Health Systems: Developing a resource for clinical translational research -- Uncertainty quantification in breast cancer risk prediction models using self-reported family health history -- Feasibility of common bibliometrics in evaluating translational science. |
Altri titoli varianti | JCTS |
Record Nr. | UNISA-996321032803316 |
Cambridge : , : Cambridge University Press, , [2017]- | ||
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Lo trovi qui: Univ. di Salerno | ||
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Journal of clinical and translational science |
Pubbl/distr/stampa | Cambridge : , : Cambridge University Press, , [2017]- |
Descrizione fisica | 1 online resource |
Disciplina | 616 |
Soggetto topico |
Medicine, Experimental
Human experimentation in medicine Clinical medicine - Research |
Soggetto genere / forma |
Periodical
Fulltext Internet Resources. Periodicals. |
ISSN | 2059-8661 |
Formato | Materiale a stampa ![]() |
Livello bibliografico | Periodico |
Lingua di pubblicazione | eng |
Nota di contenuto | Welcome to your Journal of Clinical and Translational Science -- Certification of clinical and translational researchers: An ill-conceived notion -- Enhancing Clinical Research Professionals' Training and Qualifications (ECRPTQ): Recommendations for Good Clinical Practice (GCP) training for investigators and study coordinators -- Education and training of clinical and translational study investigators and research coordinators: A competency-based approach -- Best practices in social and behavioral research: report from the Enhancing Clinical Research Professional's Training and Qualifications project -- A consult service to support and promote community-based research: Tracking and evaluating a community-based research consult service -- Mapping the evolving definitions of translational research -- Understanding investigators' attitudes through a results-based accountability framework within a single CTSA institution -- From community engagement, to community-engaged research, to broadly engaged team science -- Interdisciplinary dissemination and implementation research to advance translational science: Challenges and opportunities -- The continued evolution of team science -- Patient-Centered Network of Learning Health Systems: Developing a resource for clinical translational research -- Uncertainty quantification in breast cancer risk prediction models using self-reported family health history -- Feasibility of common bibliometrics in evaluating translational science. |
Altri titoli varianti | JCTS |
Record Nr. | UNINA-9910330745403321 |
Cambridge : , : Cambridge University Press, , [2017]- | ||
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Lo trovi qui: Univ. Federico II | ||
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Kernel Ridge Regression in Clinical Research [[electronic resource] /] / by Ton J. Cleophas, Aeilko H. Zwinderman |
Autore | Cleophas Ton J. |
Edizione | [1st ed. 2022.] |
Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2022 |
Descrizione fisica | 1 online resource (292 pages) |
Disciplina | 780 |
Soggetto topico |
Biometry
Clinical medicine - Research Statistics Data mining Big data Biostatistics Clinical Research Applied Statistics Data Mining and Knowledge Discovery Big Data Dades massives Aprenentatge automàtic Investigació mèdica |
Soggetto genere / forma | Llibres electrònics |
ISBN | 3-031-10717-9 |
Formato | Materiale a stampa ![]() |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto | 1. Traditional Kernel Regression -- 2. Kernel Ridge Regression -- 3. Optimal Scaling vs Kernel Ridge Regression -- 4. Examples of Published Kernel Ridge Regression Research So Far -- 5. Some Terminology -- 6. Effect of Being Blind on Age/Sex Adjusted Mortality Rate, 11630 Patients, Traditional Regressions vs Kernel Ridge Regression -- 7. Effect of Old Treatment on New Treatment, 35 patients, Traditional Regression vs Kernel Ridge Regression -- 8. Effect of Gene Expressions on Drug Efficacy, 250 Patients, Traditional Regressions vs Kernel Ridge Regression -- 9. Effect of Gender, Treatment, and Their Interaction on Numbers of Paroxysmal Atrial Fibrillations, 40 Patients, Traditional Regressions vs Kernel Ridge Regression -- 10. Effect of Laboratory Predictors on Septic Mortality, 200 Patients, Traditional Regressions vs Kernel Ridge Regression -- 11. Effect of Times on C-reactive Protein Levels, 18 Months, Traditional Regressions vs Kernel Ridge Regression -- 12. Effect of Different Dosages of Prednisone and Beta-agonist on Peakflow, 78 Patients, Traditional Regressions vs Kernel Ridge Regression -- 13. Effect of Race, Age, and Gender on Physical Strength, 60 Patients, Traditional Regressions vs Kernel Ridge Regression -- 14. Effect of Treatment, Age, Gender, and Co-morbidity on Hours of Sleep, 20 Patients, Traditional Regressions vs Kernel Ridge Regression -- 15. Effect of Counseling Frequency and Non-compliance on Monthly Stools, 35 Constipated Patients, Traditional Regressions vs Kernel Ridge Regression -- 16. Effect of Treatment Modality, Counseling, and Satisfaction with Doctor on Quality of Life, 450 Patients, Traditional Regressions vs Kernel Ridge Regression -- 17. Effect of Department and Patient Age Class on Risk of Falling out of Bed, 55 Patients, Traditional Regressions vs Kernel Ridge Regression -- 18. Effect of Diet, Gender, Sport, and Medical Treatment on LDL Cholesterol Reduction, 953 Patients, Traditional Regressions vs Kernel Ridge Regression -- 19. Effect of Gender, Age, Weight, and Height on Measured Body Surface, 90 Patients, Traditional Regressions vs Kernel Ridge Regression -- 20. Effect of General Practitioners' Age, Education, and Type of Practice on Lifestyle Advise Given, 139 Physicians, Traditional Regressions vs Kernel Ridge Regression -- 21. Effect of Treatment, Psychological, and Social Scores on numbers of Paroxysmal Atrial Fibrillations, 50 Patients, Traditional Regressions vs Kernel Ridge Regression -- 22. Effects of Various Predictors on Numbers of Convulsions, 3390 Patients, Traditional vs Kernel Ridge Regression -- 23. Effects of Foods Served on Breakfast Taken, 252 Persons, Traditional Regressions and Multinomial Logistic Regression vs Kernel Ridge Regression -- 24. Effect on Anorexia of Personal Factors, 217 Persons, Traditional Regression vs Kernel Ridge Regression -- 25. Effect of Physical Exercise, Calorie Intake, and Their Interaction, on Weight Loss, 64 Patients, Traditional Regressions vs Kernel Ridge Regression -- 26. Summaries. |
Record Nr. | UNINA-9910595027403321 |
Cleophas Ton J.
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Cham : , : Springer International Publishing : , : Imprint : Springer, , 2022 | ||
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Lo trovi qui: Univ. Federico II | ||
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Kreativität in der medizinischen Forschung : Fakten und Forderungen / / Hans-Harald Sedlacek, Petra Netter |
Autore | Sedlacek H. H. |
Pubbl/distr/stampa | Berlin, [Germany] ; ; Boston, [Massachusetts] : , : De Gruyter, , 2018 |
Descrizione fisica | 1 online resource (324 pages) : illustrations |
Disciplina | 610.72/4 |
Soggetto topico |
Clinical medicine - Research
Medicine, Experimental |
Soggetto genere / forma | Electronic books. |
ISBN | 3-11-047720-3 |
Formato | Materiale a stampa ![]() |
Livello bibliografico | Monografia |
Lingua di pubblicazione | ger |
Nota di contenuto | Frontmatter -- Vorwort -- Inhalt -- 1. Der Innovationsbedarf in der Medizin -- 2. Kreativität und kreative Personen -- 3. Die Innovation -- 4. Ein Rückblick: Kreative Personen als Urheber bedeutender medizinischer Innovationen -- 5. Die wesentlichen Folgerungen aus den aufgeführten kreativen und innovativen Leistungen -- 6. Die kreative Gruppe als Ort der Zusammenarbeit, Kritik und Entscheidung -- 7. Die kreative Organisation zur Schaffung von medizinischen Innovationen -- 8. Die kreative Gesellschaft als Mutterboden für medizinische Innovationen -- 9. Zusammenfassung -- 10. Haftungsausschluss -- Sachregister -- Über die Autoren |
Record Nr. | UNINA-9910467616603321 |
Sedlacek H. H.
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Berlin, [Germany] ; ; Boston, [Massachusetts] : , : De Gruyter, , 2018 | ||
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Lo trovi qui: Univ. Federico II | ||
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A manager's guide to the design and conduct of clinical trials [[electronic resource] /] / Phillip I. Good |
Autore | Good Phillip I |
Edizione | [2nd ed.] |
Pubbl/distr/stampa | Hoboken, NJ, : Wiley-Liss, c2006 |
Descrizione fisica | 1 online resource (274 p.) |
Disciplina |
610.72/4
610.724 |
Soggetto topico |
Clinical trials
Clinical medicine - Research |
Soggetto genere / forma | Electronic books. |
ISBN |
1-280-44821-0
9786610448210 0-470-32719-7 0-471-93091-1 0-471-93087-3 |
Formato | Materiale a stampa ![]() |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto |
A MANAGER'S GUIDE TO THE DESIGN AND CONDUCT OF CLINICAL TRIALS; Contents; 1 Cut Costs and Increase Profits; No Excuse for the Wastage; Front-Loaded Solution; Downsizing; Think Transnational; A Final Word; 2 Guidelines; Start with Your Reports; The Wrong Way; Keep It in the Computer; Don't Push the River; KISS; Plug the Holes as They Arise; Pay for Results, Not Intentions; Plan, Do, Then Check; PART I PLAN; 3 Prescription for Success; Plan; A. Predesign Phase; B. Design the Trials; Do; C. Obtain Regulatory Agency Approval for the Trials; D. Form the Implementation Team
E. Line Up Your Panel of PhysiciansF. Develop the Data Entry Software; G. Test the Software; H. Train; I. Recruit Patients; J. Set Up External Review Committees; K. Conduct the Trials; L. Develop Suite of Programs for Use in Data Analysis; M. Analyze and Interpret the Data; Check; N. Complete the Submission; 4 Staffing for Success; The People You Need; Design Team; Obtain Regulatory Approval for the Trials; Track Progress; Implementation Team; Develop Data Entry Software; Test the Software; Line Up Your Panel of Physicians; External Laboratories; Site Coordinators; External Review Committees Recruit and Enroll PatientsTransnational Trials; Conduct the Trials; Programs for Data Analysis; Analyze and Interpret the Data; The People You Don't Need; For Further Information; 5 Design Decisions; Should the Study Be Performed?; Should the Trials Be Transnational?; Study Objectives; End Points; Secondary End Points; Should We Proceed with a Full-Scale Trial?; Tertiary End Points; Baseline Data; Who Will Collect the Data?; Quality Control; Study Population; Timing; Closure; Planned Closure; Unplanned Closure; Be Defensive. Review, Rewrite, Review Again; Checklist for Design Budgets and ExpendituresFor Further Information; 6 Trial Design; Baseline Measurements; Controlled Randomized Clinical Trials; Randomized Trials; Blocked Randomization; Stratified Randomization; Single- vs. Double-Blind Studies; Allocation Concealment; Exceptions to the Rule; Sample Size; Which Formula?; Precision of Estimates; Bounding Type I and Type II Errors; Equivalence; Software; Subsamples; Loss Adjustment; Number of Treatment Sites; Alternate Designs; Taking Cost into Consideration; For Further Information; 7 Exception Handling; Patient Related; Missed Doses; Missed Appointments NoncomplianceAdverse Reactions; Reporting Adverse Events; When Do You Crack the Code?; Investigator Related; Lagging Recruitment; Protocol Deviations; Site-Specific Problems; Closure; Intent to Treat; Is Your Planning Complete?; PART II DO; 8 Documentation; Guidelines; Common Technical Document; Reporting Adverse Events; Initial Submission to the Regulatory Agency; Sponsor Data; Justifying the Study; Objectives; Patient Selection; Treatment Plan; Outcome Measures and Evaluation; Procedures; Clinical Follow-Up; Adverse Events; Data Management, Monitoring, Quality Control; Statistical Analysis Investigator Responsibilities |
Record Nr. | UNINA-9910143422903321 |
Good Phillip I
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Hoboken, NJ, : Wiley-Liss, c2006 | ||
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Lo trovi qui: Univ. Federico II | ||
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A manager's guide to the design and conduct of clinical trials [[electronic resource] /] / Phillip I. Good |
Autore | Good Phillip I |
Edizione | [2nd ed.] |
Pubbl/distr/stampa | Hoboken, NJ, : Wiley-Liss, c2006 |
Descrizione fisica | 1 online resource (274 p.) |
Disciplina |
610.72/4
610.724 |
Soggetto topico |
Clinical trials
Clinical medicine - Research |
ISBN |
1-280-44821-0
9786610448210 0-470-32719-7 0-471-93091-1 0-471-93087-3 |
Formato | Materiale a stampa ![]() |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto |
A MANAGER'S GUIDE TO THE DESIGN AND CONDUCT OF CLINICAL TRIALS; Contents; 1 Cut Costs and Increase Profits; No Excuse for the Wastage; Front-Loaded Solution; Downsizing; Think Transnational; A Final Word; 2 Guidelines; Start with Your Reports; The Wrong Way; Keep It in the Computer; Don't Push the River; KISS; Plug the Holes as They Arise; Pay for Results, Not Intentions; Plan, Do, Then Check; PART I PLAN; 3 Prescription for Success; Plan; A. Predesign Phase; B. Design the Trials; Do; C. Obtain Regulatory Agency Approval for the Trials; D. Form the Implementation Team
E. Line Up Your Panel of PhysiciansF. Develop the Data Entry Software; G. Test the Software; H. Train; I. Recruit Patients; J. Set Up External Review Committees; K. Conduct the Trials; L. Develop Suite of Programs for Use in Data Analysis; M. Analyze and Interpret the Data; Check; N. Complete the Submission; 4 Staffing for Success; The People You Need; Design Team; Obtain Regulatory Approval for the Trials; Track Progress; Implementation Team; Develop Data Entry Software; Test the Software; Line Up Your Panel of Physicians; External Laboratories; Site Coordinators; External Review Committees Recruit and Enroll PatientsTransnational Trials; Conduct the Trials; Programs for Data Analysis; Analyze and Interpret the Data; The People You Don't Need; For Further Information; 5 Design Decisions; Should the Study Be Performed?; Should the Trials Be Transnational?; Study Objectives; End Points; Secondary End Points; Should We Proceed with a Full-Scale Trial?; Tertiary End Points; Baseline Data; Who Will Collect the Data?; Quality Control; Study Population; Timing; Closure; Planned Closure; Unplanned Closure; Be Defensive. Review, Rewrite, Review Again; Checklist for Design Budgets and ExpendituresFor Further Information; 6 Trial Design; Baseline Measurements; Controlled Randomized Clinical Trials; Randomized Trials; Blocked Randomization; Stratified Randomization; Single- vs. Double-Blind Studies; Allocation Concealment; Exceptions to the Rule; Sample Size; Which Formula?; Precision of Estimates; Bounding Type I and Type II Errors; Equivalence; Software; Subsamples; Loss Adjustment; Number of Treatment Sites; Alternate Designs; Taking Cost into Consideration; For Further Information; 7 Exception Handling; Patient Related; Missed Doses; Missed Appointments NoncomplianceAdverse Reactions; Reporting Adverse Events; When Do You Crack the Code?; Investigator Related; Lagging Recruitment; Protocol Deviations; Site-Specific Problems; Closure; Intent to Treat; Is Your Planning Complete?; PART II DO; 8 Documentation; Guidelines; Common Technical Document; Reporting Adverse Events; Initial Submission to the Regulatory Agency; Sponsor Data; Justifying the Study; Objectives; Patient Selection; Treatment Plan; Outcome Measures and Evaluation; Procedures; Clinical Follow-Up; Adverse Events; Data Management, Monitoring, Quality Control; Statistical Analysis Investigator Responsibilities |
Record Nr. | UNINA-9910830835203321 |
Good Phillip I
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Hoboken, NJ, : Wiley-Liss, c2006 | ||
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Lo trovi qui: Univ. Federico II | ||
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