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Label-free biosensors : techniques and applications / / edited by Matthew A. Cooper [[electronic resource]]
Label-free biosensors : techniques and applications / / edited by Matthew A. Cooper [[electronic resource]]
Pubbl/distr/stampa Cambridge : , : Cambridge University Press, , 2009
Descrizione fisica 1 online resource (x, 288 pages) : digital, PDF file(s)
Disciplina 610.28/4
Soggetto topico Biosensors
ISBN 1-107-20037-7
1-283-33018-0
9786613330185
1-139-13469-8
1-139-12964-3
1-139-13357-8
0-511-50474-8
0-511-62653-3
0-511-50688-0
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Label-free optical biosensors : an introduction / Brian T. Cunningham -- Experimental design / Robert Karlsson -- Extracting affinity constants from biosensor binding responses / Rebecca L. Rich and David G. Myszka -- Extracting kinetic rate constants from binding responses / Rebecca L. Rich and David G. Myszka -- Sensor surfaces and receptor deposition / Matthew A. Cooper -- Macromolecular interactions / Francis Markey -- Interactions with membranes and membrane receptors / Matthew A. Cooper -- Application of SPR technology to pharmaceutical relevant drug-receptor interactions / Walter Huber -- High-throughput analysis of biomolecular interactions and cellular responses with resonant waveguide grating biosensors / Ye Fang ... [et al.] -- ITC-derived binding constants : using microgram quantities of protein / Richard K. Brown ... [et al.] -- Electrical impedance technology applied to cell-based assays / Ryan P. McGuinness and Edward Verdonk.
Record Nr. UNINA-9910782614103321
Cambridge : , : Cambridge University Press, , 2009
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Label-free biosensors : techniques and applications / / edited by Matthew A. Cooper [[electronic resource]]
Label-free biosensors : techniques and applications / / edited by Matthew A. Cooper [[electronic resource]]
Pubbl/distr/stampa Cambridge : , : Cambridge University Press, , 2009
Descrizione fisica 1 online resource (x, 288 pages) : digital, PDF file(s)
Disciplina 610.28/4
Soggetto topico Biosensors
ISBN 1-107-20037-7
1-283-33018-0
9786613330185
1-139-13469-8
1-139-12964-3
1-139-13357-8
0-511-50474-8
0-511-62653-3
0-511-50688-0
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Label-free optical biosensors : an introduction / Brian T. Cunningham -- Experimental design / Robert Karlsson -- Extracting affinity constants from biosensor binding responses / Rebecca L. Rich and David G. Myszka -- Extracting kinetic rate constants from binding responses / Rebecca L. Rich and David G. Myszka -- Sensor surfaces and receptor deposition / Matthew A. Cooper -- Macromolecular interactions / Francis Markey -- Interactions with membranes and membrane receptors / Matthew A. Cooper -- Application of SPR technology to pharmaceutical relevant drug-receptor interactions / Walter Huber -- High-throughput analysis of biomolecular interactions and cellular responses with resonant waveguide grating biosensors / Ye Fang ... [et al.] -- ITC-derived binding constants : using microgram quantities of protein / Richard K. Brown ... [et al.] -- Electrical impedance technology applied to cell-based assays / Ryan P. McGuinness and Edward Verdonk.
Record Nr. UNINA-9910826813903321
Cambridge : , : Cambridge University Press, , 2009
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Label-free technologies for drug discovery [[electronic resource] /] / editors, Matthew Cooper, Lorenz Mayr
Label-free technologies for drug discovery [[electronic resource] /] / editors, Matthew Cooper, Lorenz Mayr
Pubbl/distr/stampa Chichester, West Sussex, U.K., : John Wiley & Sons, 2011
Descrizione fisica 1 online resource (350 p.)
Disciplina 615.19
615/.19
Altri autori (Persone) CooperM. A (Matthew A.)
MayrLorenz
Soggetto topico Drug development
Biosensors
Pharmaceutical biotechnology
ISBN 1-119-99027-0
1-283-37396-3
9786613373960
0-470-97913-5
0-470-97912-7
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Label-Free TechnologiesFor Drug Discovery; Contents; Preface; List of Contributors; 1 The Revolution of Real-Time, Label-Free Biosensor Applications; 1.1 Introduction; 1.2 SPR Pessimists; 1.3 Setting Up Experiments; 1.4 Data Processing and Analysis; 1.5 The Good News; References; 2 Design and Implementation of Vertically Emitting Distributed Feedback Lasers for Biological Sensing; 2.1 Introduction; 2.2 DFB Laser Biosensor Design; 2.3 Fabrication and Instrumentation; 2.4 Experimental Results; 2.4.1 Vertically Emitting DFB Laser; 2.4.2 Bulk Material Sensing; 2.4.3 Sensitivity Resolution
2.4.4 Small Molecule Binding Detection2.5 Conclusions; Acknowledgements; References; 3 SPR Screening of Chemical Microarrays for Fragment-Based Discovery; 3.1 Introduction; 3.2 Key Features of Fragment Screening; 3.3 SPR Fragment Screening; 3.4 Synthesis of Library Compounds; 3.5 Library Design and Array Content; 3.6 Chemical Microarray Production; 3.7 Surface Plasmon Resonance; 3.8 SPR Imaging; 3.9 Array Visualization and Analysis; 3.10 Follow-up; 3.11 Applications: MMP Case Study; 3.11.1 Search for New Binding Modes; 3.11.2 Selectivity Studies; 3.12 Other Target Classes; 3.13 Conclusion
References4 The CellKey R System: A Label-Free Cell-Based Assay Platform for Early Drug Discovery Applications; 4.1 Introduction; 4.2 Cellular Impedance Technology; 4.3 Target Identification and Validation; 4.4 Screening and Lead Optimization; 4.5 Conclusion; References; 5 Dynamic and Label-Free Cell-Based Assays Using the xCELLigence System; 5.1 Introduction; 5.2 The xCELLigence System; 5.3 Principle of Detection; 5.4 Applications; 5.4.1 Cell Proliferation, Cytotoxicity and Time Dependent Cellular Response Profiling; 5.5 Functional Assays for G-Protein Coupled Receptors; 5.6 Conclusion
References6 Selecting the Best HTS Hits to Move Forward: ITC Ligand Binding Characterization Provides Guidance; 6.1 Introduction; 6.2 Principles of Isothermal Titration Calorimetry (ITC); 6.3 Applications of ITC in Hit Validation; 6.3.1 Assay Design for Hit Confirmation and Affinity Determination; 6.3.2 Identification of Nonspecific Binders, Unstable Protein Targets and Multiple Binding Sites; 6.3.3 High Speed ITC Hit Characterization Assays; 6.4 Applications of ITC in Fragment-Based Drug Discovery; 6.4.1 Measuring Weak Affinities by ITC; 6.5 Applications of ITC in Mechanism of Action Studies
6.6 Applications of ITC in Lead Optimization6.7 ITC as an Enzyme Activity Monitor; 6.8 Conclusion; References; 7 Incorporating Transmitted Light Modalities into High-Content Analysis Assays; 7.1 Introduction; 7.2 Transmitted Light (Bright Field) Imaging; 7.3 Image Analysis of Phase Contrast Images; 7.4 Conclusion; References; 8 Nonradioactive Rubidium Efflux Assay Technology for Screening of Ion Channels; 8.1 Introduction; 8.2 Ion Channels as Drug Targets; 8.3 Ion Channel Assays and Screening; 8.4 Nonradioactive Rubidium Efflux Assay Based on Atomic Absorption Spectrometry
8.5 A Typical Assay Protocol
Record Nr. UNINA-9910133454603321
Chichester, West Sussex, U.K., : John Wiley & Sons, 2011
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Label-free technologies for drug discovery [[electronic resource] /] / editors, Matthew Cooper, Lorenz Mayr
Label-free technologies for drug discovery [[electronic resource] /] / editors, Matthew Cooper, Lorenz Mayr
Pubbl/distr/stampa Chichester, West Sussex, U.K., : John Wiley & Sons, 2011
Descrizione fisica 1 online resource (350 p.)
Disciplina 615.19
615/.19
Altri autori (Persone) CooperM. A (Matthew A.)
MayrLorenz
Soggetto topico Drug development
Biosensors
Pharmaceutical biotechnology
ISBN 1-119-99027-0
1-283-37396-3
9786613373960
0-470-97913-5
0-470-97912-7
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Label-Free TechnologiesFor Drug Discovery; Contents; Preface; List of Contributors; 1 The Revolution of Real-Time, Label-Free Biosensor Applications; 1.1 Introduction; 1.2 SPR Pessimists; 1.3 Setting Up Experiments; 1.4 Data Processing and Analysis; 1.5 The Good News; References; 2 Design and Implementation of Vertically Emitting Distributed Feedback Lasers for Biological Sensing; 2.1 Introduction; 2.2 DFB Laser Biosensor Design; 2.3 Fabrication and Instrumentation; 2.4 Experimental Results; 2.4.1 Vertically Emitting DFB Laser; 2.4.2 Bulk Material Sensing; 2.4.3 Sensitivity Resolution
2.4.4 Small Molecule Binding Detection2.5 Conclusions; Acknowledgements; References; 3 SPR Screening of Chemical Microarrays for Fragment-Based Discovery; 3.1 Introduction; 3.2 Key Features of Fragment Screening; 3.3 SPR Fragment Screening; 3.4 Synthesis of Library Compounds; 3.5 Library Design and Array Content; 3.6 Chemical Microarray Production; 3.7 Surface Plasmon Resonance; 3.8 SPR Imaging; 3.9 Array Visualization and Analysis; 3.10 Follow-up; 3.11 Applications: MMP Case Study; 3.11.1 Search for New Binding Modes; 3.11.2 Selectivity Studies; 3.12 Other Target Classes; 3.13 Conclusion
References4 The CellKey R System: A Label-Free Cell-Based Assay Platform for Early Drug Discovery Applications; 4.1 Introduction; 4.2 Cellular Impedance Technology; 4.3 Target Identification and Validation; 4.4 Screening and Lead Optimization; 4.5 Conclusion; References; 5 Dynamic and Label-Free Cell-Based Assays Using the xCELLigence System; 5.1 Introduction; 5.2 The xCELLigence System; 5.3 Principle of Detection; 5.4 Applications; 5.4.1 Cell Proliferation, Cytotoxicity and Time Dependent Cellular Response Profiling; 5.5 Functional Assays for G-Protein Coupled Receptors; 5.6 Conclusion
References6 Selecting the Best HTS Hits to Move Forward: ITC Ligand Binding Characterization Provides Guidance; 6.1 Introduction; 6.2 Principles of Isothermal Titration Calorimetry (ITC); 6.3 Applications of ITC in Hit Validation; 6.3.1 Assay Design for Hit Confirmation and Affinity Determination; 6.3.2 Identification of Nonspecific Binders, Unstable Protein Targets and Multiple Binding Sites; 6.3.3 High Speed ITC Hit Characterization Assays; 6.4 Applications of ITC in Fragment-Based Drug Discovery; 6.4.1 Measuring Weak Affinities by ITC; 6.5 Applications of ITC in Mechanism of Action Studies
6.6 Applications of ITC in Lead Optimization6.7 ITC as an Enzyme Activity Monitor; 6.8 Conclusion; References; 7 Incorporating Transmitted Light Modalities into High-Content Analysis Assays; 7.1 Introduction; 7.2 Transmitted Light (Bright Field) Imaging; 7.3 Image Analysis of Phase Contrast Images; 7.4 Conclusion; References; 8 Nonradioactive Rubidium Efflux Assay Technology for Screening of Ion Channels; 8.1 Introduction; 8.2 Ion Channels as Drug Targets; 8.3 Ion Channel Assays and Screening; 8.4 Nonradioactive Rubidium Efflux Assay Based on Atomic Absorption Spectrometry
8.5 A Typical Assay Protocol
Record Nr. UNINA-9910830744603321
Chichester, West Sussex, U.K., : John Wiley & Sons, 2011
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Label-free technologies for drug discovery [[electronic resource] /] / editors, Matthew Cooper, Lorenz Mayr
Label-free technologies for drug discovery [[electronic resource] /] / editors, Matthew Cooper, Lorenz Mayr
Pubbl/distr/stampa Chichester, West Sussex, U.K., : John Wiley & Sons, 2011
Descrizione fisica 1 online resource (350 p.)
Disciplina 615.19
615/.19
Altri autori (Persone) CooperM. A (Matthew A.)
MayrLorenz
Soggetto topico Drug development
Biosensors
Pharmaceutical biotechnology
ISBN 1-119-99027-0
1-283-37396-3
9786613373960
0-470-97913-5
0-470-97912-7
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Label-Free TechnologiesFor Drug Discovery; Contents; Preface; List of Contributors; 1 The Revolution of Real-Time, Label-Free Biosensor Applications; 1.1 Introduction; 1.2 SPR Pessimists; 1.3 Setting Up Experiments; 1.4 Data Processing and Analysis; 1.5 The Good News; References; 2 Design and Implementation of Vertically Emitting Distributed Feedback Lasers for Biological Sensing; 2.1 Introduction; 2.2 DFB Laser Biosensor Design; 2.3 Fabrication and Instrumentation; 2.4 Experimental Results; 2.4.1 Vertically Emitting DFB Laser; 2.4.2 Bulk Material Sensing; 2.4.3 Sensitivity Resolution
2.4.4 Small Molecule Binding Detection2.5 Conclusions; Acknowledgements; References; 3 SPR Screening of Chemical Microarrays for Fragment-Based Discovery; 3.1 Introduction; 3.2 Key Features of Fragment Screening; 3.3 SPR Fragment Screening; 3.4 Synthesis of Library Compounds; 3.5 Library Design and Array Content; 3.6 Chemical Microarray Production; 3.7 Surface Plasmon Resonance; 3.8 SPR Imaging; 3.9 Array Visualization and Analysis; 3.10 Follow-up; 3.11 Applications: MMP Case Study; 3.11.1 Search for New Binding Modes; 3.11.2 Selectivity Studies; 3.12 Other Target Classes; 3.13 Conclusion
References4 The CellKey R System: A Label-Free Cell-Based Assay Platform for Early Drug Discovery Applications; 4.1 Introduction; 4.2 Cellular Impedance Technology; 4.3 Target Identification and Validation; 4.4 Screening and Lead Optimization; 4.5 Conclusion; References; 5 Dynamic and Label-Free Cell-Based Assays Using the xCELLigence System; 5.1 Introduction; 5.2 The xCELLigence System; 5.3 Principle of Detection; 5.4 Applications; 5.4.1 Cell Proliferation, Cytotoxicity and Time Dependent Cellular Response Profiling; 5.5 Functional Assays for G-Protein Coupled Receptors; 5.6 Conclusion
References6 Selecting the Best HTS Hits to Move Forward: ITC Ligand Binding Characterization Provides Guidance; 6.1 Introduction; 6.2 Principles of Isothermal Titration Calorimetry (ITC); 6.3 Applications of ITC in Hit Validation; 6.3.1 Assay Design for Hit Confirmation and Affinity Determination; 6.3.2 Identification of Nonspecific Binders, Unstable Protein Targets and Multiple Binding Sites; 6.3.3 High Speed ITC Hit Characterization Assays; 6.4 Applications of ITC in Fragment-Based Drug Discovery; 6.4.1 Measuring Weak Affinities by ITC; 6.5 Applications of ITC in Mechanism of Action Studies
6.6 Applications of ITC in Lead Optimization6.7 ITC as an Enzyme Activity Monitor; 6.8 Conclusion; References; 7 Incorporating Transmitted Light Modalities into High-Content Analysis Assays; 7.1 Introduction; 7.2 Transmitted Light (Bright Field) Imaging; 7.3 Image Analysis of Phase Contrast Images; 7.4 Conclusion; References; 8 Nonradioactive Rubidium Efflux Assay Technology for Screening of Ion Channels; 8.1 Introduction; 8.2 Ion Channels as Drug Targets; 8.3 Ion Channel Assays and Screening; 8.4 Nonradioactive Rubidium Efflux Assay Based on Atomic Absorption Spectrometry
8.5 A Typical Assay Protocol
Record Nr. UNINA-9910841044503321
Chichester, West Sussex, U.K., : John Wiley & Sons, 2011
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Macro, micro, and nano-biosensors : potential applications and possible limitations / / Mahendra Rai [and three others] editors
Macro, micro, and nano-biosensors : potential applications and possible limitations / / Mahendra Rai [and three others] editors
Edizione [1st ed. 2021.]
Pubbl/distr/stampa Cham, Switzerland : , : Springer, , [2021]
Descrizione fisica 1 online resource (XVIII, 415 p. 122 illus., 68 illus. in color.)
Disciplina 610.28
Soggetto topico Biosensors
Microbial fuel cells
Nanostructured materials
ISBN 3-030-55490-2
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Macro-, micro- and nanosensors based on biological / chemical materials -- Bactericidal, fungicidal and immunomodulating activity of nano-surfaces -- Enzymatic Tissue Biotests (MAO and AChE biotests) and Bioindicators -- Is it possible to detect less than one bacterial cell? -- SERS for bacterial, virus and protein bio-sensing -- Biosensors for virus detection -- Specific immobilization of rotaviruses for atomic force microscopy with using Langmuir antibody films based on amphiphilic polyelectrolytes -- Fluorimetric and SERS sensor systems for diagnostics and monitoring of catecholamines-dependent diseases -- Enhanced sensitivity rapid tests for the detection of sepsis marker procalcitonin -- Analytical capabilities of some biosensors for the determination of drugs -- Electrochemical DNA sensors based on nanostructured polymeric materials for determination of antitumor drugs -- Variants of amperometric biosensors in the determination of some micotoxins: analytical capabilities -- New class of diagnostic systems based on polyelectrolyte microcapsules for urea detection -- Bioluminescent nano- and micro-biosensing elements for detection of organophosphorous compounds -- Nano- and microelectrochemical biosensors for determining blood glucose -- Micro-Electrochemical SMBG Biosensor Chip Design Development for Sustainable Mass Production based on the Strategic Platform Patent Map -- Biological Fuel Cells: Applications in Health Service and Ecology -- Recent Trends in Fabrication and Applications of Wearable Bioelectronics for Early-Stage Disease Monitoring and Diagnosis -- Self-powered biosensors in medicine and ecology -- Self-powered implantable biosensors – a review of recent advancements and future perspectives.
Record Nr. UNINA-9910483711603321
Cham, Switzerland : , : Springer, , [2021]
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Metal, metal-oxides and metal sulfides for batteries, fuel cells, solar cells, photocatalysis and health sensors / / Saravanan Rajendran [and three others], editors
Metal, metal-oxides and metal sulfides for batteries, fuel cells, solar cells, photocatalysis and health sensors / / Saravanan Rajendran [and three others], editors
Pubbl/distr/stampa Cham, Switzerland : , : Springer, , [2021]
Descrizione fisica 1 online resource (350 pages)
Disciplina 620.115
Collana Environmental chemistry for a sustainable world
Soggetto topico Nanostructured materials
Fuel cells
Biosensors
Nanoestructures
Òxids metàl·lics
Piles de combustible
Soggetto genere / forma Llibres electrònics
ISBN 3-030-63791-3
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Record Nr. UNINA-9910768442203321
Cham, Switzerland : , : Springer, , [2021]
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Micro- and nanoelectromechanical biosensors / / Liviu Nicu and Thierry Leichlé
Micro- and nanoelectromechanical biosensors / / Liviu Nicu and Thierry Leichlé
Autore Nicu Liviu
Pubbl/distr/stampa London, England ; ; Hoboken, New Jersey : , : ISTE Ltd : , : John Wiley & Sons, , 2014
Descrizione fisica 1 online resource (144 p.)
Disciplina 610.28
Altri autori (Persone) LeichléThierry
Collana FOCUS. Nanoscience and Nanotechnology Series
Soggetto topico Biosensors
Nanotechnology
ISBN 1-118-76085-9
1-118-76084-0
1-118-76098-0
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Cover; Title Page; Contents; Introduction; CHAPTER 1. TRANSDUCTION TECHNIQUES FOR MINIATURIZED BIOSENSORS; 1.1. Definition of bioMEMS; 1.2. Transduction techniques; 1.2.1. Optical transduction; 1.2.2. Electro (chemical) transduction; 1.2.3. Mechanical transduction; 1.3. MEMS transducers; 1.4. One specific application of MEMS biosensors: detection of pathogen agents; 1.5. Bibliography; CHAPTER 2. BIORECEPTORS AND GRAFTING METHODS; 2.1. Types of bioreceptor; 2.1.1. Catalytic receptors; 2.1.2. Affinity receptors; 2.1.3. Nucleic acid-based receptors; 2.1.4. Molecularly imprinted polymers
2.2. Immobilization strategies2.2.1. Adsorption and antifouling strategies; 2.2.2. Entrapment methods; 2.2.3. Covalent coupling; 2.2.4. Other capture systems; 2.2.5. Immobilization strategies: summary; 2.3. Conclusion; 2.4. Bibliography; CHAPTER 3. PATTERNING TECHNIQUES FOR THE BIOFUNCTIONALIZATION OF MEMS; 3.1. What is surface patterning?; 3.2. Direct biopatterning in liquid phase; 3.2.1. Ink delivery by non-contact methods; 3.2.2. Ink delivery by contact methods; 3.3. Replication of patterns; 3.3.1. Photolithography; 3.3.2. Light-induced patterning strategies; 3.3.3. Microcontact printing
3.3.4. In-flux functionalization3.4. Conclusions; 3.5. Bibliography; CHAPTER 4. FROM MEMS TO NEMS BIOSENSORS; 4.1. Importance of downscaling; 4.2. Challenges faced by NEMS for biosensing applications; 4.2.1. Issues related to nanomechanical transducers; 4.2.2. Issues related to the functionalization of NEMS; 4.2.3. On the importance of packaging and sample preparation; 4.3. Economic considerations; 4.4. Bibliography; CHAPTER 5. COMPARING PERFORMANCES OF BIOSENSORS: IMPOSSIBLE MISSION?; 5.1. Bibliography; INDEX
Record Nr. UNINA-9910138963303321
Nicu Liviu  
London, England ; ; Hoboken, New Jersey : , : ISTE Ltd : , : John Wiley & Sons, , 2014
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Micro- and nanoelectromechanical biosensors / / Liviu Nicu and Thierry Leichlé
Micro- and nanoelectromechanical biosensors / / Liviu Nicu and Thierry Leichlé
Autore Nicu Liviu
Pubbl/distr/stampa London, England ; ; Hoboken, New Jersey : , : ISTE Ltd : , : John Wiley & Sons, , 2014
Descrizione fisica 1 online resource (144 p.)
Disciplina 610.28
Altri autori (Persone) LeichléThierry
Collana FOCUS. Nanoscience and Nanotechnology Series
Soggetto topico Biosensors
Nanotechnology
ISBN 1-118-76085-9
1-118-76084-0
1-118-76098-0
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Cover; Title Page; Contents; Introduction; CHAPTER 1. TRANSDUCTION TECHNIQUES FOR MINIATURIZED BIOSENSORS; 1.1. Definition of bioMEMS; 1.2. Transduction techniques; 1.2.1. Optical transduction; 1.2.2. Electro (chemical) transduction; 1.2.3. Mechanical transduction; 1.3. MEMS transducers; 1.4. One specific application of MEMS biosensors: detection of pathogen agents; 1.5. Bibliography; CHAPTER 2. BIORECEPTORS AND GRAFTING METHODS; 2.1. Types of bioreceptor; 2.1.1. Catalytic receptors; 2.1.2. Affinity receptors; 2.1.3. Nucleic acid-based receptors; 2.1.4. Molecularly imprinted polymers
2.2. Immobilization strategies2.2.1. Adsorption and antifouling strategies; 2.2.2. Entrapment methods; 2.2.3. Covalent coupling; 2.2.4. Other capture systems; 2.2.5. Immobilization strategies: summary; 2.3. Conclusion; 2.4. Bibliography; CHAPTER 3. PATTERNING TECHNIQUES FOR THE BIOFUNCTIONALIZATION OF MEMS; 3.1. What is surface patterning?; 3.2. Direct biopatterning in liquid phase; 3.2.1. Ink delivery by non-contact methods; 3.2.2. Ink delivery by contact methods; 3.3. Replication of patterns; 3.3.1. Photolithography; 3.3.2. Light-induced patterning strategies; 3.3.3. Microcontact printing
3.3.4. In-flux functionalization3.4. Conclusions; 3.5. Bibliography; CHAPTER 4. FROM MEMS TO NEMS BIOSENSORS; 4.1. Importance of downscaling; 4.2. Challenges faced by NEMS for biosensing applications; 4.2.1. Issues related to nanomechanical transducers; 4.2.2. Issues related to the functionalization of NEMS; 4.2.3. On the importance of packaging and sample preparation; 4.3. Economic considerations; 4.4. Bibliography; CHAPTER 5. COMPARING PERFORMANCES OF BIOSENSORS: IMPOSSIBLE MISSION?; 5.1. Bibliography; INDEX
Record Nr. UNINA-9910820544003321
Nicu Liviu  
London, England ; ; Hoboken, New Jersey : , : ISTE Ltd : , : John Wiley & Sons, , 2014
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Microfluidics and biosensors in cancer research : applications in cancer modeling and theranostics / / David Caballero, Subhas C. Kundu, and Rui L. Reis, editors
Microfluidics and biosensors in cancer research : applications in cancer modeling and theranostics / / David Caballero, Subhas C. Kundu, and Rui L. Reis, editors
Pubbl/distr/stampa Cham, Switzerland : , : Springer, , [2022]
Descrizione fisica 1 online resource (598 pages) : illustrations
Disciplina 610.28
Collana Advances in experimental medicine and biology
Soggetto topico Biosensors
Cancer - Research
Microfluidics
ISBN 3-031-04039-2
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Record Nr. UNINA-9910733712203321
Cham, Switzerland : , : Springer, , [2022]
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui