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International journal of clinical pharmacology and therapeutics
| International journal of clinical pharmacology and therapeutics |
| Pubbl/distr/stampa | München-Deisenhofen, : Dustri-Verlag Dr. Karl Feistle, ©1994- |
| Descrizione fisica | 1 online resource |
| Disciplina | 615/.1/05 |
| Soggetto topico |
Pharmacology
Chemotherapy Toxicology Biopharmaceutics Pharmacologie clinique Farmacologie Toxicologie Drug Therapy Pharmacology, Clinical |
| Soggetto genere / forma |
Periodicals.
Fulltext Internet Resources. Periodical |
| Formato | Materiale a stampa  |
| Livello bibliografico | Periodico |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Clinical pharmacology and therapeutics |
| Record Nr. | UNINA-9910147331503321 |
| München-Deisenhofen, : Dustri-Verlag Dr. Karl Feistle, ©1994- | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
International journal of clinical pharmacology and therapeutics
| International journal of clinical pharmacology and therapeutics |
| Pubbl/distr/stampa | München-Deisenhofen, : Dustri-Verlag Dr. Karl Feistle, ©1994- |
| Descrizione fisica | 1 online resource |
| Disciplina | 615/.1/05 |
| Soggetto topico |
Pharmacology
Chemotherapy Toxicology Biopharmaceutics Pharmacologie clinique Farmacologie Toxicologie Drug Therapy Pharmacology, Clinical |
| Soggetto genere / forma |
Periodicals.
Fulltext Internet Resources. Periodical |
| Formato | Materiale a stampa |
| Livello bibliografico | Periodico |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Clinical pharmacology and therapeutics |
| Record Nr. | UNISA-996335454303316 |
| München-Deisenhofen, : Dustri-Verlag Dr. Karl Feistle, ©1994- | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. di Salerno | ||
| ||
An introduction to bioanalysis of biopharmaceuticals / / Seema Kumar, editor
| An introduction to bioanalysis of biopharmaceuticals / / Seema Kumar, editor |
| Autore | Kumar Seema |
| Pubbl/distr/stampa | Cham : , : Springer International Publishing AG, , 2022 |
| Descrizione fisica | 1 online resource (166 pages) |
| Disciplina | 615.7 |
| Collana | AAPS Advances in the Pharmaceutical Sciences |
| Soggetto topico |
Biopharmaceutics
Pharmaceutical Preparations - analysis |
| ISBN |
9783030971939
9783030971922 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910590081203321 |
Kumar Seema
|
||
| Cham : , : Springer International Publishing AG, , 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Introduction to biological and small molecule drug research and development : theory and case studies / / edited by Robin Ganellin, Stanley Roberts, Roy Jefferis
| Introduction to biological and small molecule drug research and development : theory and case studies / / edited by Robin Ganellin, Stanley Roberts, Roy Jefferis |
| Pubbl/distr/stampa | Waltham, Mass., : Elsevier, 2013 |
| Descrizione fisica | 1 online resource (xx, 425 pages, 21 unnumbered pages of plates) : illustrations (some color) |
| Disciplina | 610.72 |
| Collana | Gale eBooks |
| Soggetto topico |
Drug development
Biopharmaceutics |
| ISBN | 0-12-397770-3 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Front Cover; Introduction to Biological and Small Molecule Drug Research and Development: Theory and Case Studies; Copyright; Contents; Biographies; Preface; Chapter 1 - Introduction to enzymes, receptors and the action of small molecule drugs; 1.1 SECTION I: BACKGROUND INFORMATION; 1.2 SECTION II: MORE ABOUT ENZYMES; 1.3 SECTION III: MORE ABOUT RECEPTORS; 1.4 SECTION IV; Further Reading; Chapter 2 - Protein structure and function; 2.1 INTRODUCTION; 2.2 GENERAL ASPECTS OF PROTEIN STRUCTURE; 2.3 ENZYMES; 2.4 PROTEIN RECEPTORS; 2.5 STRUCTURAL PROTEINS AS DRUG TARGETS; 2.6 PROTEINS AS DRUGS
2.7 CONCLUDING REMARKSReferences; Chapter 3 - The small molecule drug discovery process - from target selection to candidate selection; 3.1 INTRODUCTION; 3.2 WHERE DO LEADS COME FROM?; 3.3 LEAD GENERATION: ACTIVE-TO-HIT; 3.4 LEAD GENERATION: HIT-TO-LEAD; 3.5 LO - ESTABLISHING THE SCREENING CASCADE AND CANDIDATE BIOLOGICAL TARGET PROFILE; References and Notes; Further Reading; Chapter 4 - Protein therapeutics (introduction to biopharmaceuticals); 4.1 INTRODUCTION; 4.2 TYPES OF PROTEIN THERAPEUTICS I: REGULATORY AND ENZYMATIC ACTIVITY; 4.3 TYPES OF PROTEIN THERAPEUTICS II: TARGETING ACTIVITY 4.4 CHALLENGES OF PROTEIN THERAPEUTICS4.5 FUTURE DIRECTIONS FOR PROTEIN THERAPEUTICS; 4.6 BIOSIMILAR PROTEIN THERAPEUTICS; 4.7 SUMMARY AND CONCLUSIONS; References; Further Reading; Chapter 5 - Similarities and differences in the discovery and use of biopharmaceuticals and small-molecule chemotherapeutics; 5.1 INTRODUCTION; 5.2 HOW DO SMDS DIFFER FROM BIOMOLECULAR DRUGS?; 5.3 HISTORICAL CHANGES TO THE FDA APPROACH TO HANDLE THE BIOTECH BOOM-THE DIFFERING NOMENCLATURE FOR SMALL MOLECULES VS BIOLOGI ...; 5.4 COMPARISONS OF CLINICAL METRICS-BIOLOGICS VS SMALL MOLECULES 5.5 ARE PEPTIDE DRUGS SMALL MOLECULES OR BIOLOGICS?5.6 THE MANUFACTURE AND SUPPLY OF SMDS VS BIOMOLECULAR DRUGS; 5.7 THE PRICING OF SMDS VS BIOMOLECULAR DRUGS; 5.8 COMPARING SMALL-MOLECULE, PEPTIDE AND BIOMOLECULAR DRUGS IN THE MARKET; 5.9 BIOSIMILAR BIOMOLECULES VS GENERIC SMALL MOLECULES; 5.10 DISCOVERY AND PRECLINICAL STAGES FOR SMDS VS BIOMOLECULAR DRUGS-WHERE THE TECHNOLOGIES DIFFER THE MOST; 5.11 SMALL-MOLECULE AND BIOLOGICS APPROVALS BY THERAPY AREAS; 5.12 MANAGING SMALL-MOLECULE & BIOMOLECULAR DRUG R&D IN THE SAME COMPANY; 5.13 CONCLUSION; References Chapter 6 - Therapies for type 2 diabetes: modulating the incretin pathway using small molecule peptidase inhibitors or pep ...6.1 INTRODUCTION; 6.2 PHARMACOTHERAPY OF TYPE 2 DIABETES; 6.3 THE RATIONALE FOR INCRETIN-BASED THERAPIES FOR TYPE 2 DIABETES; 6.4 DISCOVERY AND PHARMACOKINETICS OF THE INCRETIN-BASED THERAPIES; 6.5 CLINICAL EFFICACY OF THE INCRETIN-BASED THERAPIES; 6.6 EVIDENCE FOR DISEASE MODIFICATION; 6.7 IMPACT ON CARDIOVASCULAR RISK; 6.8 CLINICAL SAFETY AND TOLERABILITY OF INCRETIN-BASED THERAPIES; 6.9 CONCLUSIONS; References Chapter 7 - The structure and business of biopharmaceutical companies including the management of risks and resources |
| Record Nr. | UNINA-9910792478903321 |
| Waltham, Mass., : Elsevier, 2013 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Introduction to biological and small molecule drug research and development : theory and case studies / / edited by Robin Ganellin, Stanley Roberts, Roy Jefferis
| Introduction to biological and small molecule drug research and development : theory and case studies / / edited by Robin Ganellin, Stanley Roberts, Roy Jefferis |
| Pubbl/distr/stampa | Waltham, Mass., : Elsevier, 2013 |
| Descrizione fisica | 1 online resource (xx, 425 pages, 21 unnumbered pages of plates) : illustrations (some color) |
| Disciplina | 610.72 |
| Collana | Gale eBooks |
| Soggetto topico |
Drug development
Biopharmaceutics |
| ISBN | 0-12-397770-3 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Front Cover; Introduction to Biological and Small Molecule Drug Research and Development: Theory and Case Studies; Copyright; Contents; Biographies; Preface; Chapter 1 - Introduction to enzymes, receptors and the action of small molecule drugs; 1.1 SECTION I: BACKGROUND INFORMATION; 1.2 SECTION II: MORE ABOUT ENZYMES; 1.3 SECTION III: MORE ABOUT RECEPTORS; 1.4 SECTION IV; Further Reading; Chapter 2 - Protein structure and function; 2.1 INTRODUCTION; 2.2 GENERAL ASPECTS OF PROTEIN STRUCTURE; 2.3 ENZYMES; 2.4 PROTEIN RECEPTORS; 2.5 STRUCTURAL PROTEINS AS DRUG TARGETS; 2.6 PROTEINS AS DRUGS
2.7 CONCLUDING REMARKSReferences; Chapter 3 - The small molecule drug discovery process - from target selection to candidate selection; 3.1 INTRODUCTION; 3.2 WHERE DO LEADS COME FROM?; 3.3 LEAD GENERATION: ACTIVE-TO-HIT; 3.4 LEAD GENERATION: HIT-TO-LEAD; 3.5 LO - ESTABLISHING THE SCREENING CASCADE AND CANDIDATE BIOLOGICAL TARGET PROFILE; References and Notes; Further Reading; Chapter 4 - Protein therapeutics (introduction to biopharmaceuticals); 4.1 INTRODUCTION; 4.2 TYPES OF PROTEIN THERAPEUTICS I: REGULATORY AND ENZYMATIC ACTIVITY; 4.3 TYPES OF PROTEIN THERAPEUTICS II: TARGETING ACTIVITY 4.4 CHALLENGES OF PROTEIN THERAPEUTICS4.5 FUTURE DIRECTIONS FOR PROTEIN THERAPEUTICS; 4.6 BIOSIMILAR PROTEIN THERAPEUTICS; 4.7 SUMMARY AND CONCLUSIONS; References; Further Reading; Chapter 5 - Similarities and differences in the discovery and use of biopharmaceuticals and small-molecule chemotherapeutics; 5.1 INTRODUCTION; 5.2 HOW DO SMDS DIFFER FROM BIOMOLECULAR DRUGS?; 5.3 HISTORICAL CHANGES TO THE FDA APPROACH TO HANDLE THE BIOTECH BOOM-THE DIFFERING NOMENCLATURE FOR SMALL MOLECULES VS BIOLOGI ...; 5.4 COMPARISONS OF CLINICAL METRICS-BIOLOGICS VS SMALL MOLECULES 5.5 ARE PEPTIDE DRUGS SMALL MOLECULES OR BIOLOGICS?5.6 THE MANUFACTURE AND SUPPLY OF SMDS VS BIOMOLECULAR DRUGS; 5.7 THE PRICING OF SMDS VS BIOMOLECULAR DRUGS; 5.8 COMPARING SMALL-MOLECULE, PEPTIDE AND BIOMOLECULAR DRUGS IN THE MARKET; 5.9 BIOSIMILAR BIOMOLECULES VS GENERIC SMALL MOLECULES; 5.10 DISCOVERY AND PRECLINICAL STAGES FOR SMDS VS BIOMOLECULAR DRUGS-WHERE THE TECHNOLOGIES DIFFER THE MOST; 5.11 SMALL-MOLECULE AND BIOLOGICS APPROVALS BY THERAPY AREAS; 5.12 MANAGING SMALL-MOLECULE & BIOMOLECULAR DRUG R&D IN THE SAME COMPANY; 5.13 CONCLUSION; References Chapter 6 - Therapies for type 2 diabetes: modulating the incretin pathway using small molecule peptidase inhibitors or pep ...6.1 INTRODUCTION; 6.2 PHARMACOTHERAPY OF TYPE 2 DIABETES; 6.3 THE RATIONALE FOR INCRETIN-BASED THERAPIES FOR TYPE 2 DIABETES; 6.4 DISCOVERY AND PHARMACOKINETICS OF THE INCRETIN-BASED THERAPIES; 6.5 CLINICAL EFFICACY OF THE INCRETIN-BASED THERAPIES; 6.6 EVIDENCE FOR DISEASE MODIFICATION; 6.7 IMPACT ON CARDIOVASCULAR RISK; 6.8 CLINICAL SAFETY AND TOLERABILITY OF INCRETIN-BASED THERAPIES; 6.9 CONCLUSIONS; References Chapter 7 - The structure and business of biopharmaceutical companies including the management of risks and resources |
| Record Nr. | UNINA-9910808755803321 |
| Waltham, Mass., : Elsevier, 2013 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Journal of advanced pharmaceutical technology & research
| Journal of advanced pharmaceutical technology & research |
| Pubbl/distr/stampa | [Gwalior], : [Medknow Publications and Media on behalf of Society of Pharmaceutical Education & Research], [2010]- |
| Soggetto topico |
Biopharmaceutics
Pharmaceutical technology Drug Design Pharmaceutical Preparations Pharmacology Technology, Pharmaceutical Societies, Pharmaceutical Pharmacy Pharmaceutical Industry |
| Soggetto genere / forma |
Periodical
Periodicals. |
| ISSN | 0976-2094 |
| Formato | Materiale a stampa |
| Livello bibliografico | Periodico |
| Lingua di pubblicazione | eng |
| Altri titoli varianti |
Journal of advanced pharmaceutical technology and research
JAPTR J Adv Pharm Technol Res |
| Record Nr. | UNISA-996199490303316 |
| [Gwalior], : [Medknow Publications and Media on behalf of Society of Pharmaceutical Education & Research], [2010]- | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. di Salerno | ||
| ||
Journal of advanced pharmaceutical technology & research
| Journal of advanced pharmaceutical technology & research |
| Pubbl/distr/stampa | [Gwalior], : [Medknow Publications and Media on behalf of Society of Pharmaceutical Education & Research], [2010]- |
| Soggetto topico |
Biopharmaceutics
Pharmaceutical technology Drug Design Pharmaceutical Preparations Pharmacology Technology, Pharmaceutical Societies, Pharmaceutical Pharmacy Pharmaceutical Industry |
| Soggetto genere / forma |
Periodical
Periodicals. |
| ISSN | 0976-2094 |
| Formato | Materiale a stampa |
| Livello bibliografico | Periodico |
| Lingua di pubblicazione | eng |
| Altri titoli varianti |
Journal of advanced pharmaceutical technology and research
JAPTR J Adv Pharm Technol Res |
| Record Nr. | UNINA-9910140599403321 |
| [Gwalior], : [Medknow Publications and Media on behalf of Society of Pharmaceutical Education & Research], [2010]- | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Journal of biopharmaceutical statistics
| Journal of biopharmaceutical statistics |
| Pubbl/distr/stampa | New York, NY, : Marcel Dekker, Inc |
| Disciplina | 615 |
| Soggetto topico |
Pharmacy - Statistical methods
Drugs - Testing - Statistical methods Biometry Biopharmaceutics Pharmacokinetics Pharmacology Biomedicine |
| Soggetto genere / forma |
Periodical
Periodicals. |
| ISSN | 1520-5711 |
| Formato | Materiale a stampa |
| Livello bibliografico | Periodico |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | JBS |
| Record Nr. | UNISA-996213341803316 |
| New York, NY, : Marcel Dekker, Inc | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. di Salerno | ||
| ||
Journal of biopharmaceutical statistics
| Journal of biopharmaceutical statistics |
| Pubbl/distr/stampa | New York, NY, : Marcel Dekker, Inc |
| Disciplina | 615 |
| Soggetto topico |
Pharmacy - Statistical methods
Drugs - Testing - Statistical methods Biometry Biopharmaceutics Pharmacokinetics Pharmacology Biomedicine |
| Soggetto genere / forma |
Periodical
Periodicals. |
| ISSN | 1520-5711 |
| Formato | Materiale a stampa |
| Livello bibliografico | Periodico |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | JBS |
| Record Nr. | UNINA-9910154519903321 |
| New York, NY, : Marcel Dekker, Inc | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Meta-analysis in Clinical Research: Principles and Procedures [[electronic resource] /] / by Anoop Kumar
| Meta-analysis in Clinical Research: Principles and Procedures [[electronic resource] /] / by Anoop Kumar |
| Autore | Kumar Anoop |
| Edizione | [1st ed. 2023.] |
| Pubbl/distr/stampa | Singapore : , : Springer Nature Singapore : , : Imprint : Springer, , 2023 |
| Descrizione fisica | 1 online resource (129 pages) |
| Disciplina | 610.72 |
| Soggetto topico |
Pharmacology
Medical sciences Drug development Biologicals Biopharmaceutics Preclinical Research Biologics |
| ISBN | 981-9923-70-0 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Chapter 1_Introduction -- Chapter2_Systematic literature review (SLR) -- Chapter 3_Registration and software’s -- Chapter 4_Quality Assessment of Studies -- Chapter 5_Extraction and Analysis of data -- Chapter 6_Models in Meta-analysis -- Chapter 7_Heterogeneity and Publications bias -- Chapter 8_Sensitivity and subgroup analysis -- Chapter 9_Meta-regression -- Chapter 10_Plots in Meta-analysis -- Chapter 11_Network Meta-analysis -- Chapter 12_Common mistakes -- Chapter 13_Challenges -- Chapter 14_Future Perspectives -- Chapter 15_Future perspectives. |
| Record Nr. | UNINA-9910739468403321 |
|
Kumar Anoop
|
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| Singapore : , : Springer Nature Singapore : , : Imprint : Springer, , 2023 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Soggetto topico
-
Biopharmaceutics
(106)
- Pharmacology (21)
- Pharmaceutical chemistry (19)
- Drugs - Design (16)
- Drug development (14)