Applied Physics of External Radiation Exposure : Dosimetry and Radiation Protection / / by Rodolphe Antoni, Laurent Bourgois |
Autore | Antoni Rodolphe |
Edizione | [1st ed. 2017.] |
Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2017 |
Descrizione fisica | 1 online resource (XV, 470 p. 277 illus., 21 illus. in color.) |
Disciplina | 612.01448 |
Collana | Biological and Medical Physics, Biomedical Engineering |
Soggetto topico |
Medical physics
Radiation Radiology Biomedical engineering Particle acceleration Physics Medical and Radiation Physics Diagnostic Radiology Biomedical Engineering and Bioengineering Particle Acceleration and Detection, Beam Physics Numerical and Computational Physics, Simulation |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto | Basic Physical Quantities Used in Radiation Protection for External Exposure -- Interaction of Ionizing Radiation in Tissue : Assessment of Kerma and Absorbed Dose -- Protection and Operational Quantities, Dosimeter Calibration -- Assessment of External Exposure Sources -- Principles of Protection against External Radiation Exposure -- Monte Carlo Method Applied to Dosimetry and Radiation Protection. |
Record Nr. | UNINA-9910156337103321 |
Antoni Rodolphe | ||
Cham : , : Springer International Publishing : , : Imprint : Springer, , 2017 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
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Applied tissue engineering / / edited by Minoru Ueda |
Pubbl/distr/stampa | [Place of publication not identified] : , : InTech, , [2011] |
Descrizione fisica | 1 online resource (98 pages) |
Disciplina | 610.28 |
Soggetto topico | Biomedical engineering |
ISBN | 953-51-6433-3 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Record Nr. | UNINA-9910138299703321 |
[Place of publication not identified] : , : InTech, , [2011] | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
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Applying Machine Learning for Automated Classification of Biomedical Data in Subject-Independent Settings / / by Thuy T. Pham |
Autore | Pham Thuy T |
Edizione | [1st ed. 2019.] |
Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2019 |
Descrizione fisica | 1 online resource (114 pages) |
Disciplina | 658 |
Collana | Springer Theses, Recognizing Outstanding Ph.D. Research |
Soggetto topico |
Biomedical engineering
Data mining Computational intelligence Bioinformatics Biomedical Engineering and Bioengineering Data Mining and Knowledge Discovery Computational Intelligence |
ISBN | 3-319-98675-9 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto | Introduction -- Background -- Algorithms -- Point Anomaly Detection: Application to Freezing of Gait Monitoring -- Collective Anomaly Detection: Application to Respiratory Artefact Removals -- Spike Sorting: Application to Motor Unit Action Potential Discrimination -- Conclusion . |
Record Nr. | UNINA-9910337657403321 |
Pham Thuy T | ||
Cham : , : Springer International Publishing : , : Imprint : Springer, , 2019 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
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Aptamers : Biotechnological Applications of a Next Generation Tool / / edited by Gulab Singh Yadav, Vikas Kumar, Neeraj K. Aggarwal |
Edizione | [1st ed. 2019.] |
Pubbl/distr/stampa | Singapore : , : Springer Singapore : , : Imprint : Springer, , 2019 |
Descrizione fisica | 1 online resource (XXI, 186 p. 53 illus., 51 illus. in color.) |
Disciplina | 611.01816 |
Soggetto topico |
Molecular biology
Nucleic acids Biomedical engineering Genetics Gene therapy Biotecnologia Molecular Medicine Nucleic Acid Chemistry Biomedical Engineering/Biotechnology Genetics and Genomics Gene Therapy |
Soggetto genere / forma | Llibres electrònics |
ISBN | 981-13-8836-9 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto | Aptamer: The Science of Synthetic DNA -- Recent updates for isolation of aptamers for various biothreat agents using different strategies and their role in detection applications -- Aptamer: A Futuristic Approach in Diagnosis Rivaling Antibodies -- Aptamer: Apt System for Target-specific Drug Delivery -- Aptamers: Novel therapeutic and diagnostic molecules -- Different approaches for aptamer conjugated drugs preparation -- Nucleic acid guided molecular tool for in-vivo theranostic applications -- Current development and future prospects of aptamer based protein targeting -- Aptasensor- Possible design and strategy for aptamer based sensor -- Aptamer-based biosensors for detection of environmental pollutants -- Role of aptamers in plant defense mechanism against viral diseases -- Aptamer- a next generation tool for application in agricultural industry for food safety. . |
Record Nr. | UNINA-9910373918203321 |
Singapore : , : Springer Singapore : , : Imprint : Springer, , 2019 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
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Aptamers for medical applications : from diagnosis to therapeutics / / Yiyang Dong, editor |
Pubbl/distr/stampa | Singapore : , : Springer, , [2021] |
Descrizione fisica | 1 online resource (xiii, 462 pages) : illustrations |
Disciplina | 572.85 |
Soggetto topico |
Oligonucleotides - Biotechnology
Oligonucleotides - Therapeutic use Biomedical engineering |
ISBN | 981-334-838-0 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto |
Intro -- Preface -- Introduction -- Contents -- About the Editor -- 1 Introduction of Aptamer, SELEX, and Different SELEX Variants -- 1.1 Introduction -- 1.2 Systematic Evolution of Ligands by EXponential Enrichment (SELEX) -- 1.3 Different SELEX Variants for Selection Rationalization -- 1.3.1 Reducing Screening Rounds -- 1.3.2 Furnishing More Targets Applicability -- 1.3.3 Simplifying Operations -- 1.3.4 Improving the Specificity of the Aptamer -- 1.3.5 Introducing Evaluation into the Selection Process -- 1.3.6 Other Selection Strategies -- 1.4 Perspectives -- References -- 2 Aptamer-Based Probes for Molecular Imaging -- 2.1 Introduction -- 2.2 Nuclear Imaging -- 2.2.1 Single Photon Emission Computed Tomography (SPECT) -- 2.2.2 Positron Emission Tomography (PET) -- 2.3 Magnetic Resonance Imaging -- 2.4 Ultrasound Imaging -- 2.5 Fluorescence Imaging -- 2.6 Multimodal Imaging -- 2.7 Conclusions and Perspectives -- References -- 3 Aptamer-Based Point of Care Testing Schemes -- 3.1 Introduction -- 3.2 Aptamers as Sensing Probes in POCT -- 3.3 Aptasensors-Based POCT -- 3.3.1 Aptamer-Based Lateral Flow POCT Platforms -- 3.3.2 Interferometry -- 3.3.3 DNA Origami Nanobox -- 3.3.4 Capacitive Aptasensors -- 3.3.5 Smartphone Enabled Aptasensors -- 3.3.6 Microchannels/Microfluidics -- 3.3.7 Microbeads and Nanomaterial-Based Aptasensors -- 3.3.8 Multiple Aptasensing Platforms -- 3.4 Conclusion and Future Trends -- References -- 4 Aptamer-Based Drug Delivery Systems -- 4.1 Introduction -- 4.2 Aptamers as Therapeutic Agents -- 4.3 Aptamer-Drug Conjugates -- 4.3.1 Covalent Conjugation -- 4.3.2 Physical Intercalation -- 4.4 Aptamer-Functionalized Nanoparticle Drug Delivery Systems -- 4.4.1 Inorganic Nanomaterials -- 4.4.2 Organic Nanomaterials -- 4.4.3 Biological Nanomaterials -- 4.4.4 Others -- 4.5 Challenges -- 4.6 Future Perspectives -- 4.7 Conclusion.
References -- 5 Aptamer-Based Medical Devices -- 5.1 Introduction -- 5.2 Aptamer-Based Medical Devices for Diagnosis -- 5.2.1 Biomarker Detection -- 5.2.2 Detection of Other Substances -- 5.3 Aptamer-Based Medical Devices for Therapeutics -- 5.4 Perspectives and Insights -- 5.4.1 Strengthen Fundamental Research -- 5.4.2 Learn from Antibodies -- 5.4.3 Seize the Opportunities -- References -- 6 Aptamers for Targeted Therapy -- 6.1 Introduction -- 6.2 Aptamer for Targeted Therapy of Oculopathy -- 6.2.1 Macugen (Pegaptanib) Targeting VEGF -- 6.2.2 Fovista (E10030) Targeting PDGF -- 6.2.3 Zimura (ARC1905) TargetingComplement-5 (C5) -- 6.3 Aptamers for Targeted Therapy of Coagulation -- 6.3.1 REG1 Targeting Coagulation Factor IXa -- 6.3.2 ARC19499 Targeting TFPI -- 6.3.3 ARC1779 Targeting vWF -- 6.3.4 Aptamers Targeting Thrombin -- 6.4 Aptamers for Targeted Therapy of Inflammation -- 6.4.1 Aptamers Targeting Interleukins -- 6.4.2 Aptamers Targeting Tumor Necrosis Factor (TNF) -- 6.4.3 Aptamers Targeting Chemokines -- 6.4.4 Other Inflammatory-Associated Factors -- 6.5 Aptamers for Targeted Therapy of Cancer -- 6.5.1 Aptamer as Agonist -- 6.5.2 Aptamer as Inhibitor -- 6.6 Prospects of Aptamer-Based Targeted Therapy -- References -- 7 Aptamers for Personalized Therapeutics -- 7.1 Introduction -- 7.1.1 Advantages of Aptamer -- 7.1.2 DNA Versus RNA Aptamers -- 7.1.3 Therapeutic Aptamers -- 7.2 Aptamers as Unique Therapeutic Molecules -- 7.2.1 Discovery of Aptamers Against Different Types of Cancer -- 7.2.2 Aptamers for Therapeutic Applications of Infectious Diseases -- 7.3 Aptamer Systems for Targeted Drug Delivery -- 7.3.1 Target-Specific Delivery of siRNAs: Aptamer-siRNA Conjugates -- 7.3.2 Aptamer-Drug Conjugates for Therapies -- 7.3.3 Aptamer Liposome Conjugates -- 7.3.4 Aptamer-Nanoparticles Conjugates -- 7.3.5 Antidote Aptamer for Controlled Therapy. 7.4 Gaps-Issues to be Considered -- 7.5 Future Perspective -- References -- 8 Aptamers for the Diagnosis of Infectious Diseases -- 8.1 Introduction -- 8.2 Bacterial Infectious Diseases -- 8.2.1 Cholera -- 8.2.2 Tuberculosis -- 8.2.3 Anthrax -- 8.3 Viral Infectious Diseases -- 8.3.1 Viral Hepatitis -- 8.3.2 AIDS -- 8.3.3 Viral Encephalitis -- 8.3.4 COVID-19 -- 8.4 Parasitic Infectious Disease -- 8.4.1 Malaria -- 8.4.2 Schistosomiasis -- 8.5 Other Typical Infectious Diseases -- References -- 9 Aptamers for the Diagnosis of Malign Tumors -- 9.1 Introduction -- 9.2 Aptamers in Cancer Biomarkers Discovery -- 9.3 Protein Biomarkers Analysis -- 9.3.1 Electrochemical Aptasensors -- 9.3.2 Aptamer-Based Optical Assays -- 9.4 Tumor Cells Analysis -- 9.4.1 Electrochemical Cytosensors -- 9.4.2 Optical Aptasensors -- 9.4.3 Aptamer-Based Microfluidic Cytosensors -- 9.5 Tissue Section Imaging -- 9.6 In Vivo Molecular Imaging -- 9.6.1 Fluorescence Imaging -- 9.6.2 Magnetic Resonance Imaging (MRI) -- 9.6.3 Single-Photon Emission Computed Tomography (SPECT)/Positron-Emission Tomography (PET) -- 9.6.4 Computed Tomography (CT) -- 9.7 Exosome-Sensing Aptasensors -- 9.8 Conclusion and Perspectives -- References -- 10 Aptamers for Thrombotic Diseases -- 10.1 Introduction -- 10.2 Aptamers Against Thrombin -- 10.2.1 Anti-thrombin DNA Aptamers -- 10.2.2 Anti-thrombin RNA Aptamers -- 10.2.3 Anti-thrombin Bimodular Aptamers -- 10.3 Aptamers Against FVII -- 10.4 Aptamers Against FIX -- 10.4.1 Preclinical Evaluation -- 10.4.2 Clinical Evaluation -- 10.5 Aptamers Against FX -- 10.6 Aptamers Against FXI -- 10.7 Aptamers Against FXII -- 10.8 Aptamers Against Kallikrein -- 10.9 Aptamers Against P-Selectin -- 10.9.1 Aptamers Against vWF -- 10.9.2 Aptamers Against PDGFRβ -- 10.9.3 Conclusion and Perspectives -- References -- 11 Hormone Aptamers in Endocrine-Related Diseases. 11.1 Introduction -- 11.2 Hormone-Related Aptamers -- 11.2.1 Estrogen-Related Aptamers -- 11.2.2 Progesterone-Related Aptamers -- 11.2.3 Insulin-Related Aptamers -- 11.2.4 25-HydroxyvitaminD3 Related Aptamers -- 11.2.5 Cortisol-Related Aptamers -- 11.3 Aptamer Application in Endocrine-Related Disease -- 11.3.1 Application of Aptamer in Medical Diagnosis -- 11.3.2 Application of Aptamer in Real-Time Detection -- 11.3.3 Application of Aptamer in Targeted Therapy -- 11.4 Overcome the Restrictions for Commercial Use of Aptamers -- 11.5 Discussion and Outlook -- Appendix: The Abbreviation in the Paper -- References -- 12 Aptamers for the Diagnosis and Therapy of Neurodegenerative Diseases -- 12.1 Introduction -- 12.2 The Applications of Aptamers in Neurodegenerative Diseases -- 12.2.1 The Applications of Aptamers in AD -- 12.2.2 The Applications of Aptamers in PD -- 12.2.3 The Applications of Aptamers in TSEs -- 12.2.4 The Applications of Aptamers in HD -- 12.3 Conclusions and perspectives -- References -- 13 Some Frontier Technologies for Aptamers in Medical Applications -- 13.1 Introduction -- 13.2 UVMag-SELEX -- 13.2.1 Pool Enrichment and Round Determination for UVMag-SELEX -- 13.2.2 High-Throughput Sequencing for Lead Sequences and Structural Prediction for Aptamer Candidates -- 13.2.3 UV and Microarray-Based Affinity Characterization of Aptamer Candidates for SynOP -- 13.2.4 Class-Specific Binding Ability of Practical Aptamers to Seven Organophosphorus Pesticides -- 13.3 Aptamer Biochip -- 13.3.1 Aptamer Microarray Biochip -- 13.3.2 Aptamer Microfluidic Biochip -- 13.3.3 Nanoarray and Nanofluidic Biochip -- 13.4 Native Mass Spectrometry -- 13.4.1 Native ESI-MS of Aptamer and Tetracycline Complex -- 13.4.2 Calculation of Dissociation Constants of Complexes -- 13.5 Conclusions and Perspectives -- References. 14 Perspectives of Aptamers for Medical Applications -- 14.1 Introduction -- 14.2 Merits and Demerits of Aptamer in Clinical Applications -- 14.2.1 Merits -- 14.2.2 Demerits -- 14.3 The Scenario for Aptamers in Medical Application -- 14.3.1 Point-of-Care Tests -- 14.3.2 Precision Medicine -- 14.3.3 Biomarker -- 14.4 Aptamers Application in Disease -- 14.4.1 Tumor -- 14.4.2 Non-tumor -- 14.5 Challenges for Aptamer in Medical Applications: From Bench to Bedside -- 14.5.1 Stability in Biological Media -- 14.5.2 Safety for Modified Aptamer -- 14.5.3 Adapt to the Homeostasis of the Human Body -- References. |
Record Nr. | UNINA-9910484775403321 |
Singapore : , : Springer, , [2021] | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
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Aptamers in Biotechnology / / edited by Katharina Urmann, Johanna-Gabriela Walter |
Edizione | [1st ed. 2020.] |
Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2020 |
Descrizione fisica | 1 online resource (VII, 215 p. 61 illus., 47 illus. in color.) |
Disciplina | 572.85 |
Collana | Advances in Biochemical Engineering/Biotechnology |
Soggetto topico |
Biotechnology
Immunology Nucleic acids Nanochemistry Chromatography Biomedical engineering Nucleic Acid Chemistry Biomedical Engineering and Bioengineering |
ISBN | 3-030-54061-8 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto | Biophysical Characterization of Aptamer-Target Interactions -- Impedimetric Aptamer-based Biosensors: Principles and Techniques -- Impedimetric Aptamer-based Biosensors: Applications -- Aptamer-based affinity chromatography for protein extraction and purification -- Aptamers in diagnostic and molecular imaging applications -- Aptamer-modified nanoparticles in medical applications -- Defining Target Product Profiles (TPPs) for Aptamer based diagnostics. |
Record Nr. | UNINA-9910412150203321 |
Cham : , : Springer International Publishing : , : Imprint : Springer, , 2020 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
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Architectured Materials in Nature and Engineering : Archimats / / edited by Yuri Estrin, Yves Bréchet, John Dunlop, Peter Fratzl |
Edizione | [1st ed. 2019.] |
Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2019 |
Descrizione fisica | 1 online resource (457 pages) |
Disciplina | 691 |
Collana | Springer Series in Materials Science |
Soggetto topico |
Materials de construcció
Ciència dels materials Structural materials Building materials Semiconductors Biomedical engineering Structural Materials Building Materials Biomedical Engineering and Bioengineering |
Soggetto genere / forma | Llibres electrònics |
ISBN | 3-030-11942-4 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto | Introduction -- Archetypes of Archimats -- Design and Manufacture of Architectured Materials -- Optimization of Architectured Materials -- Examples of Applications -- Architectured Materials in Nature; Toward Biomimetic Approaches. |
Record Nr. | UNINA-9910337935803321 |
Cham : , : Springer International Publishing : , : Imprint : Springer, , 2019 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
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The Art and Science of Machine Intelligence : With An Innovative Application for Alzheimer’s Detection from Speech / / by Walker H. Land Jr., J. David Schaffer |
Autore | Land Jr Walker H |
Edizione | [1st ed. 2020.] |
Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2020 |
Descrizione fisica | 1 online resource (XXII, 269 p. 140 illus., 72 illus. in color.) |
Disciplina | 621.382 |
Soggetto topico |
Electrical engineering
Biomedical engineering Pattern recognition Signal processing Image processing Speech processing systems Computational intelligence Computational linguistics Communications Engineering, Networks Biomedical Engineering and Bioengineering Pattern Recognition Signal, Image and Speech Processing Computational Intelligence Computational Linguistics |
ISBN | 3-030-18496-X |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto | Introduction -- Background for Genetic Algorithms -- Support Vector Machines (SVMs) -- The Generalized Regression Neural Network (GRNN) Oracle -- Alzheimer’s Disease (AD) Background -- Genetic Algorithm (GA)-SVM Paradigm -- GA-SVM Paradigm Applied to Detecting AD from Speech -- Classical Bayesian Networks (BN) MI Developed Bayesian Networks -- Generalization of MI methods -- Selected research studies -- Conclusion. |
Record Nr. | UNINA-9910366584503321 |
Land Jr Walker H | ||
Cham : , : Springer International Publishing : , : Imprint : Springer, , 2020 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
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Articular Cartilage Dynamics [[electronic resource] /] / by David W. Smith, Bruce S. Gardiner, Lihai Zhang, Alan J. Grodzinsky |
Autore | Smith David W |
Edizione | [1st ed. 2019.] |
Pubbl/distr/stampa | Singapore : , : Springer Singapore : , : Imprint : Springer, , 2019 |
Descrizione fisica | 1 online resource (lxiii, 738 pages) |
Disciplina | 611.0183 |
Soggetto topico |
Biomedical engineering
Medical physics Biomedical Engineering and Bioengineering Medical and Radiation Physics Regenerative Medicine/Tissue Engineering |
ISBN | 981-13-1474-8 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto | Introduction to Articular Cartilage -- Cartilage tissue homeostasis -- Cartilage tissue dynamics -- Lubrication, Friction and Wear in Diarthroidal Joints -- A systems approach to articular cartilage -- Theory for modeling articular cartilage -- Computational modeling of articular cartilage. |
Record Nr. | UNINA-9910350309403321 |
Smith David W | ||
Singapore : , : Springer Singapore : , : Imprint : Springer, , 2019 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
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Artificial Hearts [[electronic resource] ] : Technology and Therapy Management / / edited by Ming Yang |
Edizione | [1st ed. 2020.] |
Pubbl/distr/stampa | Singapore : , : Springer Singapore : , : Imprint : Springer, , 2020 |
Descrizione fisica | 1 online resource (220 pages) : illustrations |
Disciplina | 617.4120592 |
Soggetto topico |
Biomedical engineering
Engineering design Cardiac surgery Control engineering Robotics Mechatronics Biomedical Engineering/Biotechnology Engineering Design Cardiac Surgery Control, Robotics, Mechatronics Pròtesis Enginyeria biomèdica Cor artificial |
Soggetto genere / forma | Llibres electrònics |
ISBN | 981-15-4378-X |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto | Chapter 1. Evolution of Artificial Heart Technology -- Chapter 2. Mechanisms of Heart Failure -- Chapter 3. Basis of Artificial Heart Technologies -- Chapter 4. Artificial Heart: Rotary Pump -- Chapter 5. Artificial Heart: Volume-Displacement Pump -- Chapter 6. Total Artificial Heart -- Chapter 7. Evaluation of Artificial Hearts -- Chapter 8. Selection of Artificial Heart Devices -- Chapter 9. Therapy Management of VADs -- Chapter 10. Challenges of Artificial Heart Devices -- Chapter 11. A Primary Study for Biocompatible Ventricular Assist Devices. |
Record Nr. | UNINA-9910416098203321 |
Singapore : , : Springer Singapore : , : Imprint : Springer, , 2020 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
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