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Biosimilars : design and analysis of follow-on biologics / / Shein-Chung Chow
| Biosimilars : design and analysis of follow-on biologics / / Shein-Chung Chow |
| Autore | Chow Shein-Chung <1955-> |
| Edizione | [1st ed.] |
| Pubbl/distr/stampa | Boca Raton, : Taylor & Francis, 2014 |
| Descrizione fisica | 1 online resource (424 pages ) : illustrations |
| Disciplina | 615.1/9 |
| Collana | Chapman & Hall/CRC biostatistics series |
| Soggetto topico |
Pharmaceutical biotechnology
Pharmaceutical biotechnology industry Drugs - Generic substitution Pharmaceutical policy Biological products |
| ISBN |
0-429-07126-4
1-4665-7969-2 |
| Classificazione | MAT029000MED071000 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Introduction Background Fundamental Differences Regulatory Requirements Biosimilarity Interchangeability of Biological Drug Products Scientific Factors Aim and Scope of the Book Bioequivalence Experience for Small-Molecule Drug Products Background Process for Bioequivalence Assessment Issue of Drug Interchangeability Highly Variable Drugs Practical Issues Frequently Asked Questions Regulatory Requirements for Assessing Follow-On Biologics Background Definitions and Interpretations of Biosimilar Products Regulatory Requirements Review of the FDA Draft Guidances Global Harmonization Criteria for Similarity Introduction Criteria for Bioequivalence Similarity Factor for Dissolution Profile Comparison Measures of Consistency Comparison of Moment-Based and Probability-Based Criteria Alternative Criteria Statistical Methods for Assessing Average Biosimilarity Introduction Classic Methods for Assessing Biosimilarity Bayesian Methods Wilcoxon-Mann-Whitney Two One-Sided Tests Procedure Three-Arm Parallel Design General Approach for Assessing Biosimilarity Background Reproducibility Probability Development of the Biosimilarity Index Relationship of the Biosimilarity Criterion versus Variability Biosimilarity Index Based on the Bayesian Approach Consistency Approach Non-Inferiority versus Equivalence/Similarity Background Testing for Equality Testing for Noninferiority Testing for Superiority Testing for Equivalence Relationship among Testing for Noninferiority, Superiority, and Equivalence Determination of the Noninferiority Margin Sample Size Requirement When There Is a Switch in Hypothesis Testing Statistical Test for Biosimilarity in Variability Introduction Pitman-Morgan's Adjusted Test for Comparing Variabilities F -Type Test under Parallel Design Non-Parametrics Methods Alternative Methods Sample Size for Comparing Variabilities Introduction Comparing Intra-Subject Variability Comparing Inter-Subject Variability Comparing Total Variability Comparing Intra-Subject CVs Impact of Variability on Biosimilarity Limits for Assessing Follow-On Biologics Introduction Relationship between Variability and Biosimilarity Limits Scaled Biosimilarity Margins Simulations Discussions Drug Interchangeability Introduction Population and Individual Bioequivalence Interchangeability for Biosimilar Products Study Designs for Interchangeability Statistical Methods Issues on Immunogenicity Studies Introduction Regulatory Requirements Assay Development/Validation Design for Immunogenicity Studies Sample Size for Immunogenicity Studies CMC Requirements for Biological Products Introduction CMC Development Product Characterization and Specification Manufacture and Process Validation Quality Control/Assurance Reference Standards, Container Closure System, and Stability Test for Comparability in Manufacturing Process Introduction Biologic Manufacturing Process Consistency Index Test for Comparability Other Comparability Tests Stability Analysis of Biosimilar Products Introduction Regulatory Stability Guidelines on Biologicals Stability Indicating Profile and Expiration Dating Period Stability Designs Statistical Analysis Assessing Biosimilarity Using Biomarker Data Introduction Assessment of Biosimilarity Statistical Test for Biosimilarity Using Biomarker Data Numerical Study Current Issues in Biosimilar Studies Introduction Scientific Factors Current Issues References Index |
| Record Nr. | UNINA-9910822825703321 |
Chow Shein-Chung <1955->
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| Boca Raton, : Taylor & Francis, 2014 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Biosimilars handbook [[electronic resource]]
| Biosimilars handbook [[electronic resource]] |
| Edizione | [2nd ed.] |
| Pubbl/distr/stampa | [London], : SAGE, 2011 |
| Descrizione fisica | 1 online resource (56 p.) |
| Disciplina | 615.19 22 |
| Soggetto topico |
Pharmaceutical biotechnology
Pharmaceutical biotechnology industry Drugs - Generic substitution Pharmaceutical policy Biological products |
| Soggetto genere / forma | Electronic books. |
| ISBN | 1-4462-0896-6 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
""Front Cover ""; ""Contents""; ""Introduction ""; ""What this handbook covers ""; ""Whom this handbook for ""; ""Executive Summary ""; ""The importance of biosimilar medicines""; ""The health economic benefits from biosimilar medicines""; ""Nomenclature of biopharmaceuticals, including biosimilar medicines""; ""List of European Commission-approved biosimilar medicines""; ""The science and technology of biosimilar medicines""; ""Regulation of biosimilar medicines""; ""Introduction of biosimilar medicines into clinical practice""; ""The future and evolving landscape of biosimilar medicines""
""Further information""""Contributors""; ""Glossary""; ""Acronyms and Abbreviations""; ""Appendix""; ""Back Cover"" |
| Record Nr. | UNINA-9910465297803321 |
| [London], : SAGE, 2011 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Biotherapy - history, principles and practice : a practical guide to the diagnosis and treatment of disease using living organisms / / Martin Grassberger ... [et. al.], editors
| Biotherapy - history, principles and practice : a practical guide to the diagnosis and treatment of disease using living organisms / / Martin Grassberger ... [et. al.], editors |
| Edizione | [1st ed. 2013.] |
| Pubbl/distr/stampa | New York, : Springer, 2013 |
| Descrizione fisica | 1 online resource (323 p.) |
| Disciplina | 615.5 |
| Altri autori (Persone) | GrassbergerMartin |
| Soggetto topico |
Biological products
Immunotherapy |
| ISBN | 94-007-6585-1 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Preface -- Biotherapy - an Introduction -- Maggot Therapy -- Hirudotherapy -- Apitherapy - Bee Venom Therapy -- Apitherapy - The Use of Honeybee Products -- Ichthyotherapy -- Helminth Therapy -- Phage Therapy -- Animal Assisted Therapy: Benefits and Challenges -- Equine Assisted Therapy: An Overview -- Canine Olfactory Detection of Human Disease. |
| Record Nr. | UNINA-9910438131203321 |
| New York, : Springer, 2013 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Depolymerization of lignin to produce value added chemicals / / Pratima Bajpai
| Depolymerization of lignin to produce value added chemicals / / Pratima Bajpai |
| Autore | Bajpai P (Pratima) |
| Edizione | [First edition.] |
| Pubbl/distr/stampa | Hoboken, New Jersey : , : John Wiley & Sons, Inc., , [2024] |
| Descrizione fisica | 1 online resource (313 pages) |
| Disciplina | 676.12 |
| Soggetto topico |
Lignin - Biodegradation
Lignin - Industrial applications Biological products |
| ISBN |
1-394-19166-9
1-394-19165-0 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Intro -- Title Page -- Copyright Page -- List of Figures -- List of Tables -- Preface -- Acknowledgements -- 1 General Background and Introduction -- 1.1 Structural and Chemical Composition of Lignin -- 1.2 Major Backbone Units and Representative Linkages in Lignin Molecules -- 1.3 Types of Lignin -- 2 Isolation of Lignin -- 2.1 Lignosulfonates -- 2.2 Kraft Lignin -- 2.3 Soda Lignin -- 2.4 Steam Explosion Lignin -- 2.5 Organosolv Lignins -- 3 Lignin Depolymerization Technologies -- 3.1 Thermal Depolymerization -- 3.1.1 Pyrolysis -- 3.1.2 Hydrothermal Liquefaction -- 3.2 Biological Depolymerization -- 3.2.1 Lignin Depolymerization by Fungi -- 3.2.2 Lignin Depolymerization by Bacteria -- 3.2.3 Lignin Depolymerization by Enzymes -- 3.2.3.1 Laccase -- 3.2.3.2 Lignin Peroxidase -- 3.2.3.3 Manganese Peroxidase -- 3.2.3.4 Versatile Peroxidase -- 3.2.3.5 β-etherase -- 3.2.3.6 Biphenyl Bond Cleavage Enzyme -- 3.3 Chemical Depolymerization -- 3.3.1 Acid-catalyzed Depolymerization -- 3.3.2 Base-catalyzed Depolymerization -- 3.3.3 Ionic Liquid-assisted Depolymerization -- 3.3.4 Supercritical Fluids-assisted Lignin Depolymerization -- 3.3.5 Metallic Catalysis -- 3.4 Oxidative Depolymerization of Lignin -- 3.5 Microwave-aided Depolymerization -- 3.6 Electrochemical Lignin Depolymerization -- 3.7 Reductive De-polymerization of Lignin -- 4 Lignin-first Biorefining Process -- 4.1 Introduction -- 4.2 The Revolutionary "Lignin-first" Method for Lignocellulosic Catalytic Valorization -- 4.2.1 Reductive Catalytic Fractionation -- 4.2.2 From Phenolic Units to Value-added Products -- 4.3 Future Challenges -- 5 Lignin Production -- 5.1 Introduction -- 5.2 Pilot-scale -- 5.2.1 Ammonia Fiber Explosion Lignin -- 5.2.2 Steam Explosion Process -- 5.2.3 BioFlex Process -- 5.2.4 German Lignocellulose Feedstock Biorefinery Project -- 5.2.5 Proesa® Lignin.
5.2.6 FABIOLATM Lignin -- 5.2.7 Fast Pyrolysis Lignin -- 5.2.8 Sequential Liquid-lignin Recovery and Purification Technology -- 5.3 Commercial scale -- 5.3.1 LignoForceTM Technology -- 5.3.2 LignoBoostTM Technology -- 5.3.3 SunCarbon Lignin -- 5.3.4 Production of Lignosulfonates -- 5.3.5 Kraft Lignin Production -- 5.3.6 Organosolv and Soda Lignin -- 5.3.7 Thermo-mechanical Pulp-bio Lignin -- 5.4 Future Perspectives -- 6 Applications of Lignin -- 6.1 Introduction -- 6.2 Applications -- 6.2.1 Aromatics, Phenolics and Flavoring Compounds -- 6.2.2 Carbon Materials -- 6.2.3 Lignin-based Nanomaterials -- 6.2.4 Biomedical Application -- 6.2.5 Lignin-based Nanocomposites -- 6.2.6 Urethanes and Epoxy Resins -- 6.2.7 Controlled Release Fertilizer -- 6.2.8 Biosensor and Bioimaging -- 6.2.9 Hydrogen Production -- 6.2.10 Battery Material for Energy Storage -- 6.2.11 Dust Control Agent -- 6.2.12 Bitumen Modifier in Road Industry -- 6.2.13 Cement Additives and Building Material -- 6.2.14 Bioplastics -- 6.2.15 Use of Lignin as a Binder -- 6.2.16 Lignin as Dispersant -- 6.2.17 Lignin as Food Additives -- 6.2.18 Lignin as Sequestering Agent -- 6.2.19 Lignin Bio-oil -- 7 Lignin - Business and Market Scenario -- 7.1 Introduction -- 7.2 Lignin Market -- 8 Challenges and Perspectives on Lignin Valorization -- 8.1 Introduction -- 8.2 Challenges and Perspectives on Lignin Utilization -- Index -- End User License Agreement. |
| Record Nr. | UNINA-9910829863103321 |
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Bajpai P (Pratima)
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| Hoboken, New Jersey : , : John Wiley & Sons, Inc., , [2024] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Drug efficacy, safety, and biologics discovery : emerging technologies and tools / / [edited by] Sean Ekins, Jinghai J. Xu
| Drug efficacy, safety, and biologics discovery : emerging technologies and tools / / [edited by] Sean Ekins, Jinghai J. Xu |
| Pubbl/distr/stampa | Hoboken, N.J. : , : John Wiley & Sons, , 2009 |
| Descrizione fisica | 1 online resource (xvi, 408 pages, 16 unnumbered pages of plates) : illustrations (some color) |
| Disciplina | 615/.19 |
| Altri autori (Persone) |
EkinsSean
XuJinghai J |
| Collana | Wiley series on technologies for the pharmaceutical industry |
| Soggetto topico |
Drug development - Technological innovations
Pharmaceutical technology Biological products |
| ISBN |
1-282-26780-9
9786612267802 0-470-43181-4 0-470-43180-6 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Focus on the fundamentals : toward better therapeutic index prediction / Jinghai J. Xu and Li J. Yu -- High-throughput protein-based technologies and computational models for drug development, efficacy, and toxicity / Leonidas G. Alexopoulos, Julio Saez Rodriguez, and Christopher W. Espelin -- Cellular systems biology applied to preclinical safety testing : a case study of CellCiphr profiling / Lawrence Vernetti ... [et al.] -- Systems pharmacology, biomarkers, and biomolecular networks / Aram S. Adourian ... [et al.] -- Zebrafish models for human diseases and drug discovery / Hanbing Zhong, Ning-Ai Liu, and Shuo Lin -- Toxicity pathways and models : mining for potential side effects / Sean Ekins and Josef Scheiber -- Computational systems biology modeling of dosimetry and cellular response pathways / Qiang Zhang ... [et al.] --
Stem cell technology for embryotoxicity, cardiotoxicity, and hepatotoxicity evaluation / Julio C. Davila ... [et al.] -- Telemetry technology for preclinical drug discovery and development / Yi Yang --Nanotechnology to improve oral drug delivery / Mayank D. Bhavsar, Shardool Jain, and Mansoor M. Amiji -- Functional glycomics and the future of glycomic drugs / Ram Sasisekharan and Karthik Viswanathan -- Modeling efficacy and safety of engineered biologics / Jeffrey R. Chabot and Bruce Gomes -- Regulation of gene expression by small, non-coding RNAS : practical applications / Roman Herrara and Eric Tien -- Future perspectives of biological engineering in pharmaceutical research : the paradigm of modeling, mining, manipulation, and measurements / Jinghai J. Xu ... [et al.]. |
| Record Nr. | UNINA-9910145817703321 |
| Hoboken, N.J. : , : John Wiley & Sons, , 2009 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Drug efficacy, safety, and biologics discovery : emerging technologies and tools / / [edited by] Sean Ekins, Jinghai J. Xu
| Drug efficacy, safety, and biologics discovery : emerging technologies and tools / / [edited by] Sean Ekins, Jinghai J. Xu |
| Edizione | [1st ed.] |
| Pubbl/distr/stampa | Hoboken, N.J., : John Wiley & Sons, c2009 |
| Descrizione fisica | 1 online resource (xvi, 408 pages, 16 unnumbered pages of plates) : illustrations (some color) |
| Disciplina | 615/.19 |
| Altri autori (Persone) |
EkinsSean
XuJinghai J |
| Collana | Wiley series on technologies for the pharmaceutical industry |
| Soggetto topico |
Drug development - Technological innovations
Pharmaceutical technology Biological products |
| ISBN |
1-282-26780-9
9786612267802 0-470-43181-4 0-470-43180-6 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Focus on the fundamentals : toward better therapeutic index prediction / Jinghai J. Xu and Li J. Yu -- High-throughput protein-based technologies and computational models for drug development, efficacy, and toxicity / Leonidas G. Alexopoulos, Julio Saez Rodriguez, and Christopher W. Espelin -- Cellular systems biology applied to preclinical safety testing : a case study of CellCiphr profiling / Lawrence Vernetti ... [et al.] -- Systems pharmacology, biomarkers, and biomolecular networks / Aram S. Adourian ... [et al.] -- Zebrafish models for human diseases and drug discovery / Hanbing Zhong, Ning-Ai Liu, and Shuo Lin -- Toxicity pathways and models : mining for potential side effects / Sean Ekins and Josef Scheiber -- Computational systems biology modeling of dosimetry and cellular response pathways / Qiang Zhang ... [et al.] --
Stem cell technology for embryotoxicity, cardiotoxicity, and hepatotoxicity evaluation / Julio C. Davila ... [et al.] -- Telemetry technology for preclinical drug discovery and development / Yi Yang --Nanotechnology to improve oral drug delivery / Mayank D. Bhavsar, Shardool Jain, and Mansoor M. Amiji -- Functional glycomics and the future of glycomic drugs / Ram Sasisekharan and Karthik Viswanathan -- Modeling efficacy and safety of engineered biologics / Jeffrey R. Chabot and Bruce Gomes -- Regulation of gene expression by small, non-coding RNAS : practical applications / Roman Herrara and Eric Tien -- Future perspectives of biological engineering in pharmaceutical research : the paradigm of modeling, mining, manipulation, and measurements / Jinghai J. Xu ... [et al.]. |
| Record Nr. | UNINA-9910819255903321 |
| Hoboken, N.J., : John Wiley & Sons, c2009 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Food and industrial bioproducts and bioprocessing [[electronic resource] /] / edited by Nurhan Turgut Dunford
| Food and industrial bioproducts and bioprocessing [[electronic resource] /] / edited by Nurhan Turgut Dunford |
| Pubbl/distr/stampa | Ames, Iowa, : Wiley-Blackwell, 2012 |
| Descrizione fisica | 1 online resource (396 p.) |
| Disciplina | 660.6 |
| Altri autori (Persone) | DunfordNurhan Turgut <1953-> |
| Soggetto topico |
Biological products
Biotechnology Biomass |
| ISBN |
1-119-94606-9
1-283-45408-4 9786613454089 1-119-94608-5 1-119-94605-0 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Food and Industrial Bioproducts and Bioprocessing; Contents; Preface; Contributors; Abbreviations; 1 Traditional and Emerging Feedstocks for Food and Industrial Bioproduct Manufacturing; 1.1 Introduction; 1.2 Grain crops; 1.2.1 Wheat; 1.2.2 Corn; 1.2.3 Barley; 1.2.4 Sorghum; 1.3 Oil and oilseeds; 1.3.1 Rapeseed/Canola; 1.3.2 Soybeans; 1.3.3 Other Oilseeds; 1.4 Lignocellulosic biomass; 1.5 Conclusions; References; 2 Recent Processing Methods for Preparing Starch-based Bioproducts; 2.1 Introduction; 2.2 Annealing and heat-moisture treatment; 2.3 High-pressure treatment; 2.4 Microwave processing
2.5 Processes using ultrasound2.6 Processing using supercritical fluids; 2.7 Extrusion processing; 2.8 Processing by steam jet cooking; 2.9 Conclusions; References; 3 Protein Processing in Food and Bioproduct Manufacturing and Techniques for Analysis; 3.1 Introduction; 3.2 General properties of proteins; 3.3 Protein separation processes in food and bioproduct manufacturing; 3.3.1 Dry processing; 3.3.2 Wet processing; 3.4 Calculating protein yields and recovery; 3.5 Processing effects on yield and protein quality; 3.5.1 Protein characterization; 3.6 Conclusion; References 4 Advancements in Oil and Oilseed Processing4.1 Introduction; 4.2 Oilseed pretreatment; 4.2.1 Handling and storage; 4.2.2 Preparation of seeds for oil extraction; 4.2.3 Size reduction and flaking; 4.2.4 Cooking/Tempering; 4.3 Oil extraction; 4.3.1 Solvent extraction; 4.3.2 Mechanical oil expression; 4.3.3 Aqueous extraction; 4.3.4 Enzyme and surfactant-aided oil extraction; 4.3.5 Supercritical fluid technology; 4.4 Oil refining; 4.4.1 Degumming; 4.4.2 Deacidification/Refining; 4.4.3 Bleaching; 4.4.4 Deodorization; 4.4.5 Winterization; 4.5 Conclusions; References 5 Food-grade Microemulsions As Nano-scale Controlled Delivery Vehicles5.1 Introduction; 5.2 Winsor classification/phase behavior; 5.3 Theories of microemulsion formation; 5.3.1 Mixed film theory; 5.3.2 Solubilization theory; 5.3.3 Thermodynamic theory; 5.4 What makes microemulsions thermodynamically stable?; 5.5 Methods of microemulsion formation; 5.6 Polydispersity; 5.7 Composition; 5.7.1 Organic phase; 5.7.2 Aqueous phase; 5.7.3 Surfactants; 5.7.4 Co-surfactants; 5.8 Factors affecting phase behavior; 5.9 Parameters that modify microemulsion structure; 5.9.1 Critical micelle concentration 5.9.2 Critical packing parameter5.9.3 Hydrophile-lipophile balance; 5.9.4 Ingredient compatibility; 5.10 Characterization techniques; 5.10.1 Ternary phase diagrams; 5.10.2 Small angle scattering techniques; 5.10.3 Cryo-transmission electron microscopy; 5.10.4 Dynamic light scattering; 5.10.5 Nuclear magnetic resonance; 5.11 Applications; 5.11.1 Solubilization of poorly-soluble drugs; 5.11.2 Emulsified microemulsions; 5.11.3 Protection against oxidation/light; 5.11.4 Controlled release delivery systems; 5.11.5 Microemulsions as nano-reactors; 5.12 Conclusions; References 6 Emulsions, Nanoemulsions and Solid Lipid Nanoparticles as Delivery Systems in Foods |
| Record Nr. | UNINA-9910139745503321 |
| Ames, Iowa, : Wiley-Blackwell, 2012 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Food and industrial bioproducts and bioprocessing / / edited by Nurhan Turgut Dunford
| Food and industrial bioproducts and bioprocessing / / edited by Nurhan Turgut Dunford |
| Edizione | [1st ed.] |
| Pubbl/distr/stampa | Ames, Iowa, : Wiley-Blackwell, 2012 |
| Descrizione fisica | 1 online resource (396 p.) |
| Disciplina | 660.6 |
| Altri autori (Persone) | DunfordNurhan Turgut <1953-> |
| Soggetto topico |
Biological products
Biotechnology Biomass |
| ISBN |
1-119-94606-9
1-283-45408-4 9786613454089 1-119-94608-5 1-119-94605-0 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Food and Industrial Bioproducts and Bioprocessing; Contents; Preface; Contributors; Abbreviations; 1 Traditional and Emerging Feedstocks for Food and Industrial Bioproduct Manufacturing; 1.1 Introduction; 1.2 Grain crops; 1.2.1 Wheat; 1.2.2 Corn; 1.2.3 Barley; 1.2.4 Sorghum; 1.3 Oil and oilseeds; 1.3.1 Rapeseed/Canola; 1.3.2 Soybeans; 1.3.3 Other Oilseeds; 1.4 Lignocellulosic biomass; 1.5 Conclusions; References; 2 Recent Processing Methods for Preparing Starch-based Bioproducts; 2.1 Introduction; 2.2 Annealing and heat-moisture treatment; 2.3 High-pressure treatment; 2.4 Microwave processing
2.5 Processes using ultrasound2.6 Processing using supercritical fluids; 2.7 Extrusion processing; 2.8 Processing by steam jet cooking; 2.9 Conclusions; References; 3 Protein Processing in Food and Bioproduct Manufacturing and Techniques for Analysis; 3.1 Introduction; 3.2 General properties of proteins; 3.3 Protein separation processes in food and bioproduct manufacturing; 3.3.1 Dry processing; 3.3.2 Wet processing; 3.4 Calculating protein yields and recovery; 3.5 Processing effects on yield and protein quality; 3.5.1 Protein characterization; 3.6 Conclusion; References 4 Advancements in Oil and Oilseed Processing4.1 Introduction; 4.2 Oilseed pretreatment; 4.2.1 Handling and storage; 4.2.2 Preparation of seeds for oil extraction; 4.2.3 Size reduction and flaking; 4.2.4 Cooking/Tempering; 4.3 Oil extraction; 4.3.1 Solvent extraction; 4.3.2 Mechanical oil expression; 4.3.3 Aqueous extraction; 4.3.4 Enzyme and surfactant-aided oil extraction; 4.3.5 Supercritical fluid technology; 4.4 Oil refining; 4.4.1 Degumming; 4.4.2 Deacidification/Refining; 4.4.3 Bleaching; 4.4.4 Deodorization; 4.4.5 Winterization; 4.5 Conclusions; References 5 Food-grade Microemulsions As Nano-scale Controlled Delivery Vehicles5.1 Introduction; 5.2 Winsor classification/phase behavior; 5.3 Theories of microemulsion formation; 5.3.1 Mixed film theory; 5.3.2 Solubilization theory; 5.3.3 Thermodynamic theory; 5.4 What makes microemulsions thermodynamically stable?; 5.5 Methods of microemulsion formation; 5.6 Polydispersity; 5.7 Composition; 5.7.1 Organic phase; 5.7.2 Aqueous phase; 5.7.3 Surfactants; 5.7.4 Co-surfactants; 5.8 Factors affecting phase behavior; 5.9 Parameters that modify microemulsion structure; 5.9.1 Critical micelle concentration 5.9.2 Critical packing parameter5.9.3 Hydrophile-lipophile balance; 5.9.4 Ingredient compatibility; 5.10 Characterization techniques; 5.10.1 Ternary phase diagrams; 5.10.2 Small angle scattering techniques; 5.10.3 Cryo-transmission electron microscopy; 5.10.4 Dynamic light scattering; 5.10.5 Nuclear magnetic resonance; 5.11 Applications; 5.11.1 Solubilization of poorly-soluble drugs; 5.11.2 Emulsified microemulsions; 5.11.3 Protection against oxidation/light; 5.11.4 Controlled release delivery systems; 5.11.5 Microemulsions as nano-reactors; 5.12 Conclusions; References 6 Emulsions, Nanoemulsions and Solid Lipid Nanoparticles as Delivery Systems in Foods |
| Record Nr. | UNINA-9910807194003321 |
| Ames, Iowa, : Wiley-Blackwell, 2012 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Food Bioactive Compounds : Chemical Challenges and Opportunities / / edited by Smaoui Slim
| Food Bioactive Compounds : Chemical Challenges and Opportunities / / edited by Smaoui Slim |
| Pubbl/distr/stampa | Basel, Switzerland : , : MDPI - Multidisciplinary Digital Publishing Institute, , 2023 |
| Descrizione fisica | 1 online resource (426 pages) |
| Disciplina | 363.7288 |
| Soggetto topico |
Bioactive compounds
Biological products |
| ISBN | 3-0365-6792-5 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Food Bioactive Compounds |
| Record Nr. | UNINA-9910683385403321 |
| Basel, Switzerland : , : MDPI - Multidisciplinary Digital Publishing Institute, , 2023 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Food Bioconversion . Volume 2 / / edited by Alexandru Mihai Grumezescu, Alina Maria Holban
| Food Bioconversion . Volume 2 / / edited by Alexandru Mihai Grumezescu, Alina Maria Holban |
| Pubbl/distr/stampa | London : , : Academic Press, , 2017 |
| Descrizione fisica | 1 online resource (xxiv, 525 pages). : illustrations |
| Disciplina | 628.445 |
| Collana | Handbook of food bioengineering |
| Soggetto topico |
Biologicals
Biological products Food waste Food - Biotechnology |
| ISBN | 0-12-811413-4 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910583358903321 |
| London : , : Academic Press, , 2017 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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