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Mitochondria as Targets for Phytochemicals in Cancer Prevention and Therapy [[electronic resource] /] / edited by Dhyan Chandra
| Mitochondria as Targets for Phytochemicals in Cancer Prevention and Therapy [[electronic resource] /] / edited by Dhyan Chandra |
| Edizione | [1st ed. 2013.] |
| Pubbl/distr/stampa | New York, NY : , : Springer New York : , : Imprint : Springer, , 2013 |
| Descrizione fisica | 1 online resource (267 p.) |
| Disciplina | 571.6 |
| Soggetto topico |
Cell biology
Cancer research Apoptosis Cell Biology Cancer Research |
| ISBN | 1-4614-9326-9 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | OxPhos Defects and Their Role in Cancer Initiation and Progression -- Estrogen Receptor–Tumor Suppressor Protein p53 Signaling Crosstalk as Potential Targets of Xenoestrogens.- Mitochondrial Regulation of Cell-Death -- Cell Death Inducing Mechanisms of Cancer Chemopreventive Agents -- Dietary Phytochemicals Target Cancer Stem Cells for Cancer Chemoprevention.- Basic and translational research on dietary phytochemicals and cancer prevention -- Mitochondrial Reactive Oxygen Species in Proapoptotic Effect of Promising Cancer Chemopreventive Phytochemicals -- Therapeutic action of phytochemicals on cancer stem cells.- Phytochemicals, microRNAs and cancer: implications for cancer prevention and therapy.- Optical imaging of mitochondria for cancer therapy -- Targeting Cellular Signaling for Cancer Prevention and Therapy by Phytochemicals. |
| Record Nr. | UNINA-9910437849503321 |
| New York, NY : , : Springer New York : , : Imprint : Springer, , 2013 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Molecular Basis for Mitochondrial Signaling [[electronic resource] /] / edited by Tatiana K. Rostovtseva
| Molecular Basis for Mitochondrial Signaling [[electronic resource] /] / edited by Tatiana K. Rostovtseva |
| Edizione | [1st ed. 2017.] |
| Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2017 |
| Descrizione fisica | 1 online resource (XIV, 386 p. 61 illus., 54 illus. in color.) |
| Disciplina | 571.657 |
| Collana | Biological and Medical Physics, Biomedical Engineering |
| Soggetto topico |
Biophysics
Biological physics Cell cycle Apoptosis Biological and Medical Physics, Biophysics Cell Cycle Analysis |
| ISBN | 3-319-55539-1 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | From the Contents: Mitochondrial Calcium Signaling -- Systems approaches to mitochondrial calcium signaling -- The mitochondrial Calcium Uniporter: Molecular Composition And Physiological Role -- Molecular Mechanisms of Mitochondrial Ca2+ Uptake -- Ca2+ uniporter and male fertility. |
| Record Nr. | UNINA-9910254582603321 |
| Cham : , : Springer International Publishing : , : Imprint : Springer, , 2017 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Molecular exploitation of apoptosis pathways in prostate cancer [[electronic resource] /] / Natasha Kyprianou
| Molecular exploitation of apoptosis pathways in prostate cancer [[electronic resource] /] / Natasha Kyprianou |
| Autore | Kyprianou Natasha |
| Pubbl/distr/stampa | London, : Imperial College Press, 2012 |
| Descrizione fisica | 1 online resource (230 p.) |
| Disciplina | 616.99463 |
| Collana | Molecular medicine and medicinal chemistry |
| Soggetto topico |
Apoptosis
Prostate - Cancer - Treatment |
| Soggetto genere / forma | Electronic books. |
| ISBN |
1-280-66895-4
9786613645883 1-84816-450-5 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Contents; Preface; Chapter 1 Introduction: Prostate Cancer; Chapter 2 The Prostate Gland Dynamics; Chapter 3 Apoptosis Pathways Signaling Execution of Cancer Cells; 3.1 Cell Choices of Life and Death; 3.1.1 "Classic" apoptosis; 3.1.2 Anoikis; 3.2 Caspases: The Apoptosis Executioners in a Therapeutic Setting; 3.3 The Mitochondrion: A Convenient Cell-Killing Platform; 3.4 Cell Surface Death Receptors and the FAS Ligand; 3.5 Meet the BCL-2 Family: Governors of Cell Survival and Death; 3.6 The Transcriptional Controllers; 3.7 The p53 Tumor Suppressor
3.8 PTEN/PI3K/AKT: The Downstream Intracellular Players3.9 The Antagonists of Death: Inhibitors of Apoptosis Proteins (IAPs); 3.10 Apoptosis Signaling in the Endoplasmic Reticulum: A Death Platform for Stress; 3.11 The Tumor Microenvironment: Extracellular Forces Control Intracellular Death Outcomes; 3.11.1 Role of hypoxia; 3.11.2 The key growth factors; 3.11.3 Inflammation; Chapter 4 Androgen Receptor-Mediated Apoptosis: Significance in Development of Castration-Resistant Prostate Cancer; 4.1 The Androgen Receptor (AR); 4.2 Androgen Ablation: The Glory and the Failures 4.3 AR Status in Castration-Resistant Prostate Cancer4.4 AR Interactions with Growth Factor Signaling Leads to Apoptosis; 4.4.1 AR connects with EGF; 4.4.2 AR and IGF interactions; 4.4.3 AR and TGF-β: partners in life and death (of the cell); 4.4.4 AR and FGF interactions; 4.4.5 AR and VEGF: Vascular exchanges for the "road"; 4.4.6 AR and growth factor interplay in the stroma; Chapter 5 Anoikis in Prostate Cancer Metastasis; 5.1 Anoikis Interrupted: Survival of the Homeless (Cells); 5.2 The Integrin Connection; 5.3 Impairing the Route to Angiogenesis; 5.3.1 Doxazosin; 5.3.2 Suramin 5.3.3 Thalidomide5.3.4 Bevacizumab; 5.3.5 SU5416; 5.4 Anoikis and the Tumor Microenvironment: No "Resting" in the Stroma; 5.5 Signaling the "Homeless" State: Intracellular Anoikis Effectors; 5.6 Significance of Apoptosis in Cytoskeleton and Microtubule Targeting; 5.7 Autophagy: The Cellular Benefits of Starving to Death; Chapter 6 Epithelial-Mesenchymal Transition (EMT) in Prostate Cancer Metastasis; Chapter 7 Novel Molecular Therapeutics for Targeting Castration-Resistant Prostate Cancer; 7.1 Therapeutic Targeting of TGF-β Signaling 7.2 Exploitation of Quinazolines: Lifting Anoikis Resistance to Impair Metastasis7.3 Receptor Tyrosine Kinase Targeting; 7.4 Histone Deacetylase Inhibitors (HDACs): Therapeutic Inhibitors; 7.5 Selective Death Action by Cancer-Specific PAR-4 in Prostate Tumors; 7.6 Death Synergy Between Proteosome and Death Receptor Leads to Tumor Regression; 7.7 The SERCA Pump as a Therapeutic Target; 7.8 Endothelin-Receptor Antagonists; 7.9 The Power of Sex Steroid Targeting; Chapter 8 Apoptotic-Based Molecular Markers of Therapeutic Response; Chapter 9 Role of Apoptosis in Prostate Cancer Prevention 9.1 Aspirin and Non-Aspirin Nonsteroidal Anti-Inflammatory Drugs (NSAIDs) |
| Record Nr. | UNINA-9910451821703321 |
Kyprianou Natasha
|
||
| London, : Imperial College Press, 2012 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Molecular exploitation of apoptosis pathways in prostate cancer [[electronic resource] /] / Natasha Kyprianou
| Molecular exploitation of apoptosis pathways in prostate cancer [[electronic resource] /] / Natasha Kyprianou |
| Autore | Kyprianou Natasha |
| Pubbl/distr/stampa | London, : Imperial College Press, 2012 |
| Descrizione fisica | 1 online resource (230 p.) |
| Disciplina | 616.99463 |
| Collana | Molecular medicine and medicinal chemistry |
| Soggetto topico |
Apoptosis
Prostate - Cancer - Treatment |
| ISBN |
1-280-66895-4
9786613645883 1-84816-450-5 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Contents; Preface; Chapter 1 Introduction: Prostate Cancer; Chapter 2 The Prostate Gland Dynamics; Chapter 3 Apoptosis Pathways Signaling Execution of Cancer Cells; 3.1 Cell Choices of Life and Death; 3.1.1 "Classic" apoptosis; 3.1.2 Anoikis; 3.2 Caspases: The Apoptosis Executioners in a Therapeutic Setting; 3.3 The Mitochondrion: A Convenient Cell-Killing Platform; 3.4 Cell Surface Death Receptors and the FAS Ligand; 3.5 Meet the BCL-2 Family: Governors of Cell Survival and Death; 3.6 The Transcriptional Controllers; 3.7 The p53 Tumor Suppressor
3.8 PTEN/PI3K/AKT: The Downstream Intracellular Players3.9 The Antagonists of Death: Inhibitors of Apoptosis Proteins (IAPs); 3.10 Apoptosis Signaling in the Endoplasmic Reticulum: A Death Platform for Stress; 3.11 The Tumor Microenvironment: Extracellular Forces Control Intracellular Death Outcomes; 3.11.1 Role of hypoxia; 3.11.2 The key growth factors; 3.11.3 Inflammation; Chapter 4 Androgen Receptor-Mediated Apoptosis: Significance in Development of Castration-Resistant Prostate Cancer; 4.1 The Androgen Receptor (AR); 4.2 Androgen Ablation: The Glory and the Failures 4.3 AR Status in Castration-Resistant Prostate Cancer4.4 AR Interactions with Growth Factor Signaling Leads to Apoptosis; 4.4.1 AR connects with EGF; 4.4.2 AR and IGF interactions; 4.4.3 AR and TGF-β: partners in life and death (of the cell); 4.4.4 AR and FGF interactions; 4.4.5 AR and VEGF: Vascular exchanges for the "road"; 4.4.6 AR and growth factor interplay in the stroma; Chapter 5 Anoikis in Prostate Cancer Metastasis; 5.1 Anoikis Interrupted: Survival of the Homeless (Cells); 5.2 The Integrin Connection; 5.3 Impairing the Route to Angiogenesis; 5.3.1 Doxazosin; 5.3.2 Suramin 5.3.3 Thalidomide5.3.4 Bevacizumab; 5.3.5 SU5416; 5.4 Anoikis and the Tumor Microenvironment: No "Resting" in the Stroma; 5.5 Signaling the "Homeless" State: Intracellular Anoikis Effectors; 5.6 Significance of Apoptosis in Cytoskeleton and Microtubule Targeting; 5.7 Autophagy: The Cellular Benefits of Starving to Death; Chapter 6 Epithelial-Mesenchymal Transition (EMT) in Prostate Cancer Metastasis; Chapter 7 Novel Molecular Therapeutics for Targeting Castration-Resistant Prostate Cancer; 7.1 Therapeutic Targeting of TGF-β Signaling 7.2 Exploitation of Quinazolines: Lifting Anoikis Resistance to Impair Metastasis7.3 Receptor Tyrosine Kinase Targeting; 7.4 Histone Deacetylase Inhibitors (HDACs): Therapeutic Inhibitors; 7.5 Selective Death Action by Cancer-Specific PAR-4 in Prostate Tumors; 7.6 Death Synergy Between Proteosome and Death Receptor Leads to Tumor Regression; 7.7 The SERCA Pump as a Therapeutic Target; 7.8 Endothelin-Receptor Antagonists; 7.9 The Power of Sex Steroid Targeting; Chapter 8 Apoptotic-Based Molecular Markers of Therapeutic Response; Chapter 9 Role of Apoptosis in Prostate Cancer Prevention 9.1 Aspirin and Non-Aspirin Nonsteroidal Anti-Inflammatory Drugs (NSAIDs) |
| Record Nr. | UNINA-9910779279003321 |
|
Kyprianou Natasha
|
||
| London, : Imperial College Press, 2012 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Molecular exploitation of apoptosis pathways in prostate cancer [[electronic resource] /] / Natasha Kyprianou
| Molecular exploitation of apoptosis pathways in prostate cancer [[electronic resource] /] / Natasha Kyprianou |
| Autore | Kyprianou Natasha |
| Edizione | [1st ed.] |
| Pubbl/distr/stampa | London, : Imperial College Press, 2012 |
| Descrizione fisica | 1 online resource (230 p.) |
| Disciplina | 616.99463 |
| Collana | Molecular medicine and medicinal chemistry |
| Soggetto topico |
Apoptosis
Prostate - Cancer - Treatment |
| ISBN |
1-280-66895-4
9786613645883 1-84816-450-5 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Contents; Preface; Chapter 1 Introduction: Prostate Cancer; Chapter 2 The Prostate Gland Dynamics; Chapter 3 Apoptosis Pathways Signaling Execution of Cancer Cells; 3.1 Cell Choices of Life and Death; 3.1.1 "Classic" apoptosis; 3.1.2 Anoikis; 3.2 Caspases: The Apoptosis Executioners in a Therapeutic Setting; 3.3 The Mitochondrion: A Convenient Cell-Killing Platform; 3.4 Cell Surface Death Receptors and the FAS Ligand; 3.5 Meet the BCL-2 Family: Governors of Cell Survival and Death; 3.6 The Transcriptional Controllers; 3.7 The p53 Tumor Suppressor
3.8 PTEN/PI3K/AKT: The Downstream Intracellular Players3.9 The Antagonists of Death: Inhibitors of Apoptosis Proteins (IAPs); 3.10 Apoptosis Signaling in the Endoplasmic Reticulum: A Death Platform for Stress; 3.11 The Tumor Microenvironment: Extracellular Forces Control Intracellular Death Outcomes; 3.11.1 Role of hypoxia; 3.11.2 The key growth factors; 3.11.3 Inflammation; Chapter 4 Androgen Receptor-Mediated Apoptosis: Significance in Development of Castration-Resistant Prostate Cancer; 4.1 The Androgen Receptor (AR); 4.2 Androgen Ablation: The Glory and the Failures 4.3 AR Status in Castration-Resistant Prostate Cancer4.4 AR Interactions with Growth Factor Signaling Leads to Apoptosis; 4.4.1 AR connects with EGF; 4.4.2 AR and IGF interactions; 4.4.3 AR and TGF-β: partners in life and death (of the cell); 4.4.4 AR and FGF interactions; 4.4.5 AR and VEGF: Vascular exchanges for the "road"; 4.4.6 AR and growth factor interplay in the stroma; Chapter 5 Anoikis in Prostate Cancer Metastasis; 5.1 Anoikis Interrupted: Survival of the Homeless (Cells); 5.2 The Integrin Connection; 5.3 Impairing the Route to Angiogenesis; 5.3.1 Doxazosin; 5.3.2 Suramin 5.3.3 Thalidomide5.3.4 Bevacizumab; 5.3.5 SU5416; 5.4 Anoikis and the Tumor Microenvironment: No "Resting" in the Stroma; 5.5 Signaling the "Homeless" State: Intracellular Anoikis Effectors; 5.6 Significance of Apoptosis in Cytoskeleton and Microtubule Targeting; 5.7 Autophagy: The Cellular Benefits of Starving to Death; Chapter 6 Epithelial-Mesenchymal Transition (EMT) in Prostate Cancer Metastasis; Chapter 7 Novel Molecular Therapeutics for Targeting Castration-Resistant Prostate Cancer; 7.1 Therapeutic Targeting of TGF-β Signaling 7.2 Exploitation of Quinazolines: Lifting Anoikis Resistance to Impair Metastasis7.3 Receptor Tyrosine Kinase Targeting; 7.4 Histone Deacetylase Inhibitors (HDACs): Therapeutic Inhibitors; 7.5 Selective Death Action by Cancer-Specific PAR-4 in Prostate Tumors; 7.6 Death Synergy Between Proteosome and Death Receptor Leads to Tumor Regression; 7.7 The SERCA Pump as a Therapeutic Target; 7.8 Endothelin-Receptor Antagonists; 7.9 The Power of Sex Steroid Targeting; Chapter 8 Apoptotic-Based Molecular Markers of Therapeutic Response; Chapter 9 Role of Apoptosis in Prostate Cancer Prevention 9.1 Aspirin and Non-Aspirin Nonsteroidal Anti-Inflammatory Drugs (NSAIDs) |
| Record Nr. | UNINA-9910809645803321 |
|
Kyprianou Natasha
|
||
| London, : Imperial College Press, 2012 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Molecular Mechanisms of Tumor Cell Resistance to Chemotherapy [[electronic resource] ] : Targeted Therapies to Reverse Resistance / / edited by Benjamin Bonavida
| Molecular Mechanisms of Tumor Cell Resistance to Chemotherapy [[electronic resource] ] : Targeted Therapies to Reverse Resistance / / edited by Benjamin Bonavida |
| Edizione | [1st ed. 2013.] |
| Pubbl/distr/stampa | New York, NY : , : Springer New York : , : Imprint : Springer, , 2013 |
| Descrizione fisica | 1 online resource (270 p.) |
| Disciplina | 616.99407 |
| Collana | Resistance to Targeted Anti-Cancer Therapeutics |
| Soggetto topico |
Cancer research
Apoptosis Cell biology Drug resistance Cancer Research Cell Biology Drug Resistance |
| ISBN | 1-4614-7070-6 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Preface -- Multidrug resistance in cancer: a tale of ABC drug transporters -- Multidrug resistance: a role for membrane physics, pH and drug transporters -- Mechanisms and potential therapies for acquired resistance to inhibitors targeting the Raf or MEK kinases in cancer -- Mechanisms of resistance to targeted B-Raf therapies -- Role of β1integrins in the complication and drug resistance against lung cancer: targeting β1integrins to eradicate lung cancer -- Aldo-keto reductases as new therapeutic targets for colon cancer chemoresistance -- Overcoming drug resistance through elevation of ROS in cancer -- Cancer stem cells in resistance to cytotoxic drugs: implications in chemotherapy -- Two birds with a stone: molecular cancer therapy targeting signal transduction and DNA repair pathways -- Collateral sensitivity in drug-resistant tumor cells -- Human cancer resistance to trail-apoptotic pathway-targeted therapies -- The dark side of apoptosis -- Index. |
| Record Nr. | UNINA-9910437855203321 |
| New York, NY : , : Springer New York : , : Imprint : Springer, , 2013 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Molecules, Systems and Signaling in Liver Injury [[electronic resource] /] / edited by Wen-Xing Ding, Xiao-Ming Yin
| Molecules, Systems and Signaling in Liver Injury [[electronic resource] /] / edited by Wen-Xing Ding, Xiao-Ming Yin |
| Edizione | [1st ed. 2017.] |
| Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2017 |
| Descrizione fisica | 1 online resource (290 pages) : illustrations (some color) |
| Disciplina | 617.1 |
| Collana | Cell Death in Biology and Diseases |
| Soggetto topico |
Cell cycle
Apoptosis Cell physiology Hepatology Cell membranes Cell Cycle Analysis Cell Physiology Membrane Biology |
| ISBN | 3-319-58106-6 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910253941703321 |
| Cham : , : Springer International Publishing : , : Imprint : Springer, , 2017 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Necrotic Cell Death [[electronic resource] /] / edited by Han-Ming Shen, Peter Vandenabeele
| Necrotic Cell Death [[electronic resource] /] / edited by Han-Ming Shen, Peter Vandenabeele |
| Edizione | [1st ed. 2014.] |
| Pubbl/distr/stampa | New York, NY : , : Springer New York : , : Imprint : Humana, , 2014 |
| Descrizione fisica | 1 online resource (402 p.) |
| Disciplina | 571.936 |
| Collana | Cell Death in Biology and Diseases |
| Soggetto topico |
Cell cycle
Apoptosis Oxidative stress Cell biology Cell Cycle Analysis Oxidative Stress Cell Biology |
| ISBN | 1-4614-8220-8 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Necrotic cell death at a glance: concept, mechanisms and biological functions -- Necroptosis: Alternative death modality under death receptors -- RIP1 and RIP3 in necrotic cell death -- PARP-mediated necrotic cell death -- Autophagic cell death, true or false? -- Oxidative stress and necrotic cell death -- Necrosis and DNA damage -- Lysosomes in necrotic cell death.- Necrotic cell death in development -- Necrotic cell death in immunity -- Necrotic cell death in inflammation -- Necrotic cell death and cancer -- Necrotic cell death in ischemia reperfusion injury -- Necrostatin, a necrosis inhibitor as a therapeutic agent -- Necrotic cell death in model organisms (C. elegan) -- Methodology in studying necrotic cell death. |
| Record Nr. | UNINA-9910298337103321 |
| New York, NY : , : Springer New York : , : Imprint : Humana, , 2014 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Neurotoxicity research
| Neurotoxicity research |
| Pubbl/distr/stampa | [Amsterdam?], : Harwood Academic Publishers |
| Descrizione fisica | 1 online resource |
| Soggetto topico |
Neurotoxicology
Toxicology Neurotoxic agents Nervous system - Degeneration Nervous system - Regeneration Neurosciences Neurons - drug effects Apoptosis Cytoprotection Nerve Degeneration Nerve Regeneration Neurotoxins |
| Soggetto genere / forma | Periodical |
| ISSN | 1476-3524 |
| Formato | Materiale a stampa |
| Livello bibliografico | Periodico |
| Lingua di pubblicazione | eng |
| Record Nr. | UNISA-996207254103316 |
| [Amsterdam?], : Harwood Academic Publishers | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. di Salerno | ||
| ||
Neurotoxicity research
| Neurotoxicity research |
| Pubbl/distr/stampa | [Amsterdam?], : Harwood Academic Publishers |
| Descrizione fisica | 1 online resource |
| Soggetto topico |
Neurotoxicology
Toxicology Neurotoxic agents Nervous system - Degeneration Nervous system - Regeneration Neurosciences Neurons - drug effects Apoptosis Cytoprotection Nerve Degeneration Nerve Regeneration Neurotoxins |
| Soggetto genere / forma | Periodical |
| ISSN | 1476-3524 |
| Formato | Materiale a stampa |
| Livello bibliografico | Periodico |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910154513103321 |
| [Amsterdam?], : Harwood Academic Publishers | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Soggetto topico
-
Apoptosis
(73)
- Cell death (14)
- Cancer Research (10)
- Cancer research (10)
- Oxidative Stress (8)