Autophagy |
Pubbl/distr/stampa | [Georgetown, TX] : , : Landes Bioscience, , [2005]- |
Descrizione fisica | 1 online resource |
Disciplina | 571.9 |
Soggetto topico |
Cell death
Apoptosis Homeostasis Autophagic vacuoles Lysosomes Autophagy Cell Death Autofagie Autofàgia |
Soggetto genere / forma |
Periodical
Periodicals. Revistes electròniques. |
ISSN | 1554-8635 |
Formato | Materiale a stampa ![]() |
Livello bibliografico | Periodico |
Lingua di pubblicazione | eng |
Record Nr. | UNISA-996218148803316 |
[Georgetown, TX] : , : Landes Bioscience, , [2005]- | ||
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Lo trovi qui: Univ. di Salerno | ||
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Autophagy |
Pubbl/distr/stampa | [Georgetown, TX] : , : Landes Bioscience, , [2005]- |
Descrizione fisica | 1 online resource |
Disciplina | 571.9 |
Soggetto topico |
Cell death
Apoptosis Homeostasis Autophagic vacuoles Lysosomes Autophagy Cell Death Autofagie Autofàgia |
Soggetto genere / forma |
Periodical
Periodicals. Revistes electròniques. |
ISSN | 1554-8635 |
Formato | Materiale a stampa ![]() |
Livello bibliografico | Periodico |
Lingua di pubblicazione | eng |
Record Nr. | UNINA-9910145030203321 |
[Georgetown, TX] : , : Landes Bioscience, , [2005]- | ||
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Lo trovi qui: Univ. Federico II | ||
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Cancer and Chemoprevention: An Overview [[electronic resource] /] / by Summya Rashid |
Autore | Rashid Summya |
Edizione | [1st ed. 2017.] |
Pubbl/distr/stampa | Singapore : , : Springer Singapore : , : Imprint : Springer, , 2017 |
Descrizione fisica | 1 online resource (173 pages) : illustrations (some color), tables |
Disciplina | 616.99405 |
Soggetto topico |
Cancer research
Apoptosis Gene expression Cell cycle Immunology Cancer Research Gene Expression Cell Cycle Analysis |
ISBN | 981-10-2579-7 |
Formato | Materiale a stampa ![]() |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto | Introduction -- Hallmarks of Cancer -- Classification of Cancer -- Factors Influencing Cancer Development -- Carcinogenesis -- Molecular Mechanism of Carcinogenesis -- Oxidative Stress Induced Carcinogenesis -- Major Mediators Linking Inflammation and Cancer -- Apoptosis -- Chemoprevention -- Classification of Chemopreventive Agents -- Preclinical Development of Chemo Preventive Agents for Chemoprevention -- Modulation of Wnt/β-Catenin Signaling by Chemo Prevention -- Modulation of Akt/mTOR Pathway Signaling by Chemo Prevention -- Novel Chemopreventive Agents -- Chemoprevention by Resveratrol -- Chemoprevention by Genistein -- Chemoprevention by Apigenin -- Chemoprevention by Curcumin -- Chemoprevention by Fisetin -- Chemoprevention by Epigallocatechin-3-gallate (EGCG) -- Chemoprevention by Graviola -- Cancer Chemoprevention: Hurdles and Future Prospects and Considerations -- Clinical Trials of Chemoprevention -- Future of Chemoprevention. |
Record Nr. | UNINA-9910253920303321 |
Rashid Summya
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Singapore : , : Springer Singapore : , : Imprint : Springer, , 2017 | ||
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Lo trovi qui: Univ. Federico II | ||
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Caspases [[electronic resource] /] / Yuri Lazebnik |
Autore | Lazebnik Yuri |
Pubbl/distr/stampa | London, : Henry Stewart Talks, 2007 |
Descrizione fisica | 1 online resource (1 streaming video file (43 min.) : color, sound) |
Collana | Apoptosis : fundamentals, pathways, clinical applications and role in disease |
Soggetto topico |
Apoptosis
Caspases |
Formato | Videoregistrazioni ![]() |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto | Contents: What makes apoptotic cells alike? -- What are caspases? -- From the worm to humans -- What is special about proteases? -- What do blood clotting and apoptosis have in common? -- How do caspases disassemble a cell? -- How do you find out if caspases are active? -- How are caspases activated? -- What is left to learn?. |
Record Nr. | UNINA-9910728790103321 |
Lazebnik Yuri
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London, : Henry Stewart Talks, 2007 | ||
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Lo trovi qui: Univ. Federico II | ||
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Caspases : roles and significance in cell death and disease / / Jeffrey Warren, editor |
Pubbl/distr/stampa | Hauppauge, New York : , : Nova Science Publisher's, Incorporated, , [2016] |
Descrizione fisica | 1 online resource (160 pages) : illustrations |
Disciplina | 571.9/36 |
Collana | Cell biology research progress |
Soggetto topico |
Apoptosis
Cell death |
ISBN | 1-5361-0260-1 |
Formato | Materiale a stampa ![]() |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Record Nr. | UNINA-9910150313603321 |
Hauppauge, New York : , : Nova Science Publisher's, Incorporated, , [2016] | ||
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Lo trovi qui: Univ. Federico II | ||
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Cell Death [[electronic resource] ] : Mechanism and Disease / / edited by Hao Wu |
Edizione | [1st ed. 2014.] |
Pubbl/distr/stampa | New York, NY : , : Springer New York : , : Imprint : Springer, , 2014 |
Descrizione fisica | 1 online resource (280 p.) |
Disciplina |
570
571.6 571.936 572696 |
Soggetto topico |
Cell biology
Cell physiology Proteins Apoptosis Medicine Cell Biology Cell Physiology Receptors Biomedicine, general |
ISBN | 1-4614-9302-1 |
Formato | Materiale a stampa ![]() |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto | 1. Historical Perspective – the Seven Ages of Cell Death Research -- 2. The Intrinsic Apoptotic Pathway -- 3. Molecular Basis of Cell Death Programs in Mature T Cell Homeostasis -- 4. Bcl-2 family and their therapeutic potential -- 5. IAP proteins and their therapeutic potential -- 6. Cell Death and Cancer -- 7. The DNA damage response mediates apoptosis and tumor suppression -- 8. Neuronal Death Mechanisms in Development and Disease -- 9. The Complex Interplay Between Metabolism and Apoptosis -- 10. Programmed Necrosis/Necroptosis: An Inflammatory Form of Cell Death -- 11. Structural Perspectives on BCL-2 Family of Proteins -- 12. Structural basis of death receptor signaling. |
Record Nr. | UNINA-9910298334703321 |
New York, NY : , : Springer New York : , : Imprint : Springer, , 2014 | ||
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Lo trovi qui: Univ. Federico II | ||
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Cell death [[electronic resource] /] / editors, Gerry Melino, David Vaux |
Pubbl/distr/stampa | Chichester, West Sussex ; ; Hoboken, NJ, : John Wiley & Sons, 2010 |
Descrizione fisica | 1 online resource (317 p.) |
Disciplina | 571.9/36 |
Altri autori (Persone) |
MelinoGerry
VauxDavid |
Soggetto topico |
Apoptosis
Cell death |
Soggetto genere / forma | Electronic books. |
ISBN |
1-282-54809-3
9786612548093 0-470-68657-X |
Formato | Materiale a stampa ![]() |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto |
Cover; Cell Death; Copyright Page; Contents; Contributors; Preface; The Siren's Song: This Death That Makes Life Live; References; Further Reading; The Origin and Evolution of Programmed Cell Death; Introduction; Origins: From the Question 'When' to the Question 'How'; From Predator/Prey Coevolution to Symbioses: A 'Red Queen' Hypothesis in the Bacteria World; A Stable Evolutionary Strategy despite High Individual Costs; The 'Original Sin' Hypothesis: Self-destruction as an Unavoidable Consequence of Life; C. elegans Model: From Paradigm to Paradox; Walking Around the Evolutionary Bush
From the Origins of Programmed Cell Death to the Origins of Ageing'There is Grandeur in This View of Life...'; References; Further Reading; Cell Death in C. elegans; ced-3, ced-4, ced-9 and egl-1 are Conserved Genes Essential for Programmed Cell Death in C. elegans; Regulation of Cell Death during Somatic Development; Engulfment of Dying Cells; Germline Apoptosis; DNA Damage-induced Germline Apoptosis; Conclusion; References; Further Reading; Caspases and Cell Death; History and Classification; Structure and Active Site; Substrate Recognition and Mechanism of Action; Sequence of Action Substrates during ApoptosisInhibitors; Caspase Knockouts; Pathological Implications; Therapeutic Outlook; References; Further Reading; The Apoptosome: The Executioner of Mitochondria-mediated Apoptosis; Introduction; The Apoptosome Structure: Its Components and Its Assembly; Apaf1; Apoptosome assembly; Caspase-9; Cytochrome c; Modulation of the Apoptosome Formation; Apoptosome-like Complexes in Evolution. Is the Mitochondrial Pathway of Apoptosis Conserved?; Caenorhabditis elegans; Drosophila melanogaster; The Role of the Apoptosome in Mammalian Development; Caspase-9 knockout; Apaf1 knockout Cytochrome c deficiencyFinal Remarks; References; Further Reading; Caspases, Substrates and Sequential Activation; Introduction; Caspases Classification and Structure; Pathways That Lead to Caspase Activation; Extrinsic pathway; Granzyme B pathway; Intrinsic pathway; Effectors of demolition; Demolition Phase of Apoptosis; Detachment, rounding and blebbing; Nuclear fragmentation, DNA condensation and degradation; Undermining cell physiology; Immune Clearance and Immune Tolerance of Apoptotic Cells; Conclusions; Acknowledgements; References; Further Reading; Dismantling the Apoptotic Cell IntroductionCaspases: Regulators of the Apoptotic Process; Activation of the apoptotic caspases; Effect of caspase-mediated cleavage on target substrates - gain- or loss-of-function; Cleavage of caspase substrates leads to key morphological changes during apoptosis; Cytoskeletal events and membrane blebbing; Nuclear events; Changes in the Golgi apparatus; Caspases alter the transcriptional and translational machinery; Survival pathways are targeted during apoptosis; The apoptotic cell calls for its own disposal; Caspase-independent cell death; Concluding Remarks; References; Further Reading The BCL-2 Family Proteins - Key Regulators and Effectors of Apoptosis |
Record Nr. | UNINA-9910459346203321 |
Chichester, West Sussex ; ; Hoboken, NJ, : John Wiley & Sons, 2010 | ||
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Lo trovi qui: Univ. Federico II | ||
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Cell death [[electronic resource] /] / editors, Gerry Melino, David Vaux |
Pubbl/distr/stampa | Chichester, West Sussex ; ; Hoboken, NJ, : John Wiley & Sons, 2010 |
Descrizione fisica | 1 online resource (317 p.) |
Disciplina | 571.9/36 |
Altri autori (Persone) |
MelinoGerry
VauxDavid |
Soggetto topico |
Apoptosis
Cell death |
ISBN |
1-282-54809-3
9786612548093 0-470-68657-X |
Formato | Materiale a stampa ![]() |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto |
Cover; Cell Death; Copyright Page; Contents; Contributors; Preface; The Siren's Song: This Death That Makes Life Live; References; Further Reading; The Origin and Evolution of Programmed Cell Death; Introduction; Origins: From the Question 'When' to the Question 'How'; From Predator/Prey Coevolution to Symbioses: A 'Red Queen' Hypothesis in the Bacteria World; A Stable Evolutionary Strategy despite High Individual Costs; The 'Original Sin' Hypothesis: Self-destruction as an Unavoidable Consequence of Life; C. elegans Model: From Paradigm to Paradox; Walking Around the Evolutionary Bush
From the Origins of Programmed Cell Death to the Origins of Ageing'There is Grandeur in This View of Life...'; References; Further Reading; Cell Death in C. elegans; ced-3, ced-4, ced-9 and egl-1 are Conserved Genes Essential for Programmed Cell Death in C. elegans; Regulation of Cell Death during Somatic Development; Engulfment of Dying Cells; Germline Apoptosis; DNA Damage-induced Germline Apoptosis; Conclusion; References; Further Reading; Caspases and Cell Death; History and Classification; Structure and Active Site; Substrate Recognition and Mechanism of Action; Sequence of Action Substrates during ApoptosisInhibitors; Caspase Knockouts; Pathological Implications; Therapeutic Outlook; References; Further Reading; The Apoptosome: The Executioner of Mitochondria-mediated Apoptosis; Introduction; The Apoptosome Structure: Its Components and Its Assembly; Apaf1; Apoptosome assembly; Caspase-9; Cytochrome c; Modulation of the Apoptosome Formation; Apoptosome-like Complexes in Evolution. Is the Mitochondrial Pathway of Apoptosis Conserved?; Caenorhabditis elegans; Drosophila melanogaster; The Role of the Apoptosome in Mammalian Development; Caspase-9 knockout; Apaf1 knockout Cytochrome c deficiencyFinal Remarks; References; Further Reading; Caspases, Substrates and Sequential Activation; Introduction; Caspases Classification and Structure; Pathways That Lead to Caspase Activation; Extrinsic pathway; Granzyme B pathway; Intrinsic pathway; Effectors of demolition; Demolition Phase of Apoptosis; Detachment, rounding and blebbing; Nuclear fragmentation, DNA condensation and degradation; Undermining cell physiology; Immune Clearance and Immune Tolerance of Apoptotic Cells; Conclusions; Acknowledgements; References; Further Reading; Dismantling the Apoptotic Cell IntroductionCaspases: Regulators of the Apoptotic Process; Activation of the apoptotic caspases; Effect of caspase-mediated cleavage on target substrates - gain- or loss-of-function; Cleavage of caspase substrates leads to key morphological changes during apoptosis; Cytoskeletal events and membrane blebbing; Nuclear events; Changes in the Golgi apparatus; Caspases alter the transcriptional and translational machinery; Survival pathways are targeted during apoptosis; The apoptotic cell calls for its own disposal; Caspase-independent cell death; Concluding Remarks; References; Further Reading The BCL-2 Family Proteins - Key Regulators and Effectors of Apoptosis |
Record Nr. | UNINA-9910792418603321 |
Chichester, West Sussex ; ; Hoboken, NJ, : John Wiley & Sons, 2010 | ||
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Lo trovi qui: Univ. Federico II | ||
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Cell death [[electronic resource] /] / editors, Gerry Melino, David Vaux |
Pubbl/distr/stampa | Chichester, West Sussex ; ; Hoboken, NJ, : John Wiley & Sons, 2010 |
Descrizione fisica | 1 online resource (317 p.) |
Disciplina | 571.9/36 |
Altri autori (Persone) |
MelinoGerry
VauxDavid |
Soggetto topico |
Apoptosis
Cell death |
ISBN |
1-282-54809-3
9786612548093 0-470-68657-X |
Formato | Materiale a stampa ![]() |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto |
Cover; Cell Death; Copyright Page; Contents; Contributors; Preface; The Siren's Song: This Death That Makes Life Live; References; Further Reading; The Origin and Evolution of Programmed Cell Death; Introduction; Origins: From the Question 'When' to the Question 'How'; From Predator/Prey Coevolution to Symbioses: A 'Red Queen' Hypothesis in the Bacteria World; A Stable Evolutionary Strategy despite High Individual Costs; The 'Original Sin' Hypothesis: Self-destruction as an Unavoidable Consequence of Life; C. elegans Model: From Paradigm to Paradox; Walking Around the Evolutionary Bush
From the Origins of Programmed Cell Death to the Origins of Ageing'There is Grandeur in This View of Life...'; References; Further Reading; Cell Death in C. elegans; ced-3, ced-4, ced-9 and egl-1 are Conserved Genes Essential for Programmed Cell Death in C. elegans; Regulation of Cell Death during Somatic Development; Engulfment of Dying Cells; Germline Apoptosis; DNA Damage-induced Germline Apoptosis; Conclusion; References; Further Reading; Caspases and Cell Death; History and Classification; Structure and Active Site; Substrate Recognition and Mechanism of Action; Sequence of Action Substrates during ApoptosisInhibitors; Caspase Knockouts; Pathological Implications; Therapeutic Outlook; References; Further Reading; The Apoptosome: The Executioner of Mitochondria-mediated Apoptosis; Introduction; The Apoptosome Structure: Its Components and Its Assembly; Apaf1; Apoptosome assembly; Caspase-9; Cytochrome c; Modulation of the Apoptosome Formation; Apoptosome-like Complexes in Evolution. Is the Mitochondrial Pathway of Apoptosis Conserved?; Caenorhabditis elegans; Drosophila melanogaster; The Role of the Apoptosome in Mammalian Development; Caspase-9 knockout; Apaf1 knockout Cytochrome c deficiencyFinal Remarks; References; Further Reading; Caspases, Substrates and Sequential Activation; Introduction; Caspases Classification and Structure; Pathways That Lead to Caspase Activation; Extrinsic pathway; Granzyme B pathway; Intrinsic pathway; Effectors of demolition; Demolition Phase of Apoptosis; Detachment, rounding and blebbing; Nuclear fragmentation, DNA condensation and degradation; Undermining cell physiology; Immune Clearance and Immune Tolerance of Apoptotic Cells; Conclusions; Acknowledgements; References; Further Reading; Dismantling the Apoptotic Cell IntroductionCaspases: Regulators of the Apoptotic Process; Activation of the apoptotic caspases; Effect of caspase-mediated cleavage on target substrates - gain- or loss-of-function; Cleavage of caspase substrates leads to key morphological changes during apoptosis; Cytoskeletal events and membrane blebbing; Nuclear events; Changes in the Golgi apparatus; Caspases alter the transcriptional and translational machinery; Survival pathways are targeted during apoptosis; The apoptotic cell calls for its own disposal; Caspase-independent cell death; Concluding Remarks; References; Further Reading The BCL-2 Family Proteins - Key Regulators and Effectors of Apoptosis |
Record Nr. | UNINA-9910821097203321 |
Chichester, West Sussex ; ; Hoboken, NJ, : John Wiley & Sons, 2010 | ||
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Lo trovi qui: Univ. Federico II | ||
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Cell Death Signaling in Cancer Biology and Treatment [[electronic resource] /] / edited by Daniel Johnson |
Edizione | [1st ed. 2013.] |
Pubbl/distr/stampa | New York, NY : , : Springer New York : , : Imprint : Humana, , 2013 |
Descrizione fisica | 1 online resource (411 p.) |
Disciplina | 616.99406 |
Collana | Cell Death in Biology and Diseases |
Soggetto topico |
Cell biology
Apoptosis Cancer research Cell Biology Cancer Research |
ISBN |
1-283-91194-9
1-4614-5847-1 |
Formato | Materiale a stampa ![]() |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto | Defective Apoptosis Signaling in Cancer -- The Warburg Effect and Beyond: Metabolic Dependencies for Cancer Cells -- Emerging Opportunities for Targeting the Tumor-Stroma Interactions for Increasing the Efficacy of Chemotherapy -- The Role of Autophagy in Drug Resistance and Potential for Therapeutic Targeting -- microRNAs in Cell Death and Cancer -- Targeting DNA Repair Pathways for Cancer Therapy -- Molecular Chaperones and How Addiction Matters in Cancer Therapy -- Sphingolipid Metabolism and Signaling as a Target for Cancer Treatment -- Leading Small Molecule Inhibitors of Anti-apoptotic Bcl-2 Family Members -- SMAC IAP Addiction in Cancer -- Harnessing Death Receptor Signaling for Cancer Treatment -- Proteasome Inhibition as a Novel Strategy for Cancer Treatment -- New Agents and Approaches for Targeting the RAS/RAF/MEK/ERK and PI3K/AKT/mTOR Cell Survival Pathways -- Activation of Immune-Mediated Tumor Cell Death by Chemotherapy. |
Record Nr. | UNINA-9910437833103321 |
New York, NY : , : Springer New York : , : Imprint : Humana, , 2013 | ||
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Lo trovi qui: Univ. Federico II | ||
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